NAGAOKA Shigetaka 長岡成孝

Researcher Number	10155913
External Links
Affiliation (based on the past Project Information) *help	2007: Kagoshima University, 大学院・医歯学総合研究科, 准教授 2007: Kagoshima University, Graduate School of Medical and Dental Sciences, Associate Professor 2006: Kagoshima University, Graduate School of Medical and Dental Sciences, Associate Professor, 大学院医歯学総合研究科, 助教授 2003 – 2005: Kagoshima university, Graduate School of Medical and Dental Sciences, Associate Professor, 大学院・医歯学総合研究科, 助教授 1998 – 2002: 鹿児島大学, 歯学部, 助教授 1989 – 1996: 鹿児島大学, 歯学部, 助教授
Review Section/Research Field	Principal Investigator Conservative dentistry / Conservative dentistry / Periodontal dentistry Except Principal Investigator Conservative dentistry / Conservative dentistry
Keywords	Principal Investigator 象牙質・歯髄複合体 / vanilloid receptor subtype 1 (VR1) / dentin-pulp complex / S.mitis / サイトカイン / 根管浸出液 / tooth pain / 刺激物質 / 象牙質・歯髄複合体培養系 / 歯髄疼痛 … More / pulp capping agent / restorative material / 覆髄剤 / 修復材 / 象牙質・歯随複合体 / Periodontal tissue regeneration / Enamel protein / 歯周組織再生 / エナメルタンパク / cytokine / dentin-pulp / 歯髄修復機構 / periodontitis / super antigen / 歯周炎 / スーパー抗原 / 遺伝子発現 / 難治性根尖性歯周炎 / 炎症性サイトカイン / 根尖部病変 / 根尖性歯周炎 / インタ-ロイキンー2 / 根光部病変 / 感染根管歯 … More Except Principal Investigator IL-6 / VR-1 / AP-1 / Sp-1 / p38 MAPK / ERK MAPK / PAR-2 / アポトーシス / MAPK / TNF-α / 歯髄細胞 / TNF / 歯髄炎 / substance P / MAPキナーゼ / CB2 / 細胞死 / フローサイトメトリー / MTTアッセイ / アナンダマイド / サブスタンスP / apoptosis / Inflammatory cytokines / Temperature-sensitive receptor / Dental pulp cells / TNF-a / 炎症性サイトカイン / 温度感受性受容体 / Cavity / Dentin / Enamel / Grinding / High-pressure water / 歯髄 / 噴流水 / 窩洞 / 象牙質 / エナメル質 / 研削 / 高圧水 / Roxithromycin / extracellularmatrix / periodontitis / pulpitis / chronic inflammation / vascular endothelial growth factor / LPS / 歯肉線維芽細胞 / アンチセンスオリゴヌクレオチド / 分化 / 遊走 / tenascin / MMP / in vivo / 歯槽骨再生 / 歯髄再生 / 覆罩 / ロキシスロマイシン / 細胞外基質 / 歯周炎 / 歯随炎 / 慢性炎症 / 血管内皮増殖因子 / Oral anaerbers / 根管内細菌 / Pulpitis / Immunohistochemistry / Dentinal tubules / Immunoglobulins / Dentinal caries / 細菌染色 / 酵素抗体法 / 象牙細管 / 免疫グロブリン / 象牙質う蝕 Less

A new culture system for studying in vitro human dental pulp repairPrincipal Investigator
- Principal Investigator
  
  NAGAOKA Shigetaka
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Conservative dentistry
- Research Institution
  Kagoshima University
Identification of switching factor that determinates life and death of human dental pulp cells
- Principal Investigator
  
  TOKUBA Masayuki
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Conservative dentistry
- Research Institution
  Kagoshima University
Expression and characterization of vanilloid receptor subtype 1 in human dental pulp cell cultures.
- Principal Investigator
  
  TOKUDA Masayuki
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Conservative dentistry
- Research Institution
  Kagoshima University
Trial manufacture of the water jet equipment for the cavity formation and the tooth pulp removal.
- Principal Investigator
  
  KANIE Takahito
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Conservative dentistry
- Research Institution
  Kagoshima University
Expression of enamel matrix protein in vitroPrincipal Investigator
- Principal Investigator
  
  NAGAOKA Shigetaka
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Kagoshima University
Development of analyzing system for studying human dental pulp repairPrincipal Investigator
- Principal Investigator
  
  NAGAOKA Shigetaka
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Conservative dentistry
- Research Institution
  Kagoshima University
Application of vascular endothelial growth factor in conservative dentistry
- Principal Investigator
  
  TORII Mitsuo
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Conservative dentistry
- Research Institution
  KagoshimaUniversity
A new culture system for studying in vitro human dental pulp repairPrincipal Investigator
- Principal Investigator
  
  NAGAOKA Shigetaka
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Conservative dentistry
- Research Institution
  Kagoshima University
Possible pathogenic effect of Streptococcus mitis super antigen on oral epithelial cellsPrincipal Investigator
- Principal Investigator
  
  NAGAOKA Shigetaka
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Conservative dentistry
- Research Institution
  Kagoshima University
難治性根尖性歯周尖におけるインターロイキン-1,6,および8遺伝子の発現Principal Investigator
- Principal Investigator
  
  長岡成孝
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Conservative dentistry
- Research Institution
  Kagoshima University
根尖性歯周炎における根管浸出液および根尖部病変組織中の各種サイトカインの動態Principal Investigator
- Principal Investigator
  
  長岡成孝
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Conservative dentistry
- Research Institution
  Kagoshima University
Cytokine induetion in severe periapical pathosis by oral anaerobes
- Principal Investigator
  
  KAWAGOE Masataka
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Conservative dentistry
- Research Institution
  Kagoshima University
感染根管歯における根管浸出液および根尖部病変組織中のインタ-ロイキンー2の動態Principal Investigator
- Principal Investigator
  
  長岡成孝
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Conservative dentistry
- Research Institution
  Kagoshima University
Effects of immunoglobulins on human dentinal caries
- Principal Investigator
  
  KAWAGOE Masataka
- Project Period (FY)
  1989 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Conservative dentistry
- Research Institution
  Kagoshima University

All 2006 2005 2004 Other

All Journal Article

[Journal Article] 培養歯髄細胞におけるサブスタンスPのIL-6誘導に対するMAPキナーゼと転写因子の関与2006
- Author(s)
  徳田雅行, 作田哲也, 小山徹, 達山祥子, 長岡成孝, 鳥居光男
- Journal Title
  
  日本歯科保存学会誌 49・4
  
  Pages: 552-557
- Data Source
  KAKENHI-PROJECT-17591998
[Journal Article] Substance P activates p38 mitogen-activated protein kinase to promote IL-6 induction in human dental pulp fibroblasts2005
- Author(s)
  Masayuki Tokuda, Rie Miyamoto, Tetsuya Sakuta, Shigetaka Nagaoka, Mitsuo Torii
- Journal Title
  
  Connective Tissue Research 46
  
  Pages: 153-158
- NAID
  10018086965
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591998
[Journal Article] Substance P activates p38 mitogen-activated protein kinase to promote IL-6 induction in human dental pulp fibroblasts2005
- Author(s)
  Tokuda M., Miyamoto R., Sakuta T., Nagaoka S., Torii M.
- Journal Title
  
  Connect. Tissue Res. 46
  
  Pages: 153-158
- NAID
  10018086965
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591998
[Journal Article] Substance P enhances expression of lipopolysaccharide-induced inflammatory factors in dental pulp cells2004
- Author(s)
  Tokuda M, Miyamoto R, Nagaoka S, Torii M
- Journal Title
  
  Journal of Endodontics 30
  
  Pages: 770-774
- Data Source
  KAKENHI-PROJECT-15592024
[Journal Article] Expression and characterization of vanilloid receptor subtype 1 in human dental pulp cell cultures.
- Author(s)
  Miyamoto R, Tokuda M, Sakuta T, Nagaoka S, Tori M
- Journal Title
  
  Journal of Endodontics (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15592024
[Journal Article] Expression and characterization of vanilloid receptor subtype 1 in human dental pulp cell cultures.
- Author(s)
  R.Miyamoto, M.Tokuda, T.Sakuta, S.Nagaoka, M.Torii
- Journal Title
  
  Journal of Endodontics (in press)
- Data Source
  KAKENHI-PROJECT-15592024
[Journal Article] Expression and characterization of vanilloid receptor subtype 1 in human dental pulp cell cultures.
- Author(s)
  R.Miyamoto, M.Tokuda, T.Sakuta, S.Nagaoka, M.Tori
- Journal Title
  
  Journal of Endodontics (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15592024

1. TOKUDA Masayuki (20253891)

# of Collaborated Projects: 6 results

# of Collaborated Products: 7 results
2. MATSUSHITA Kenji (90253898)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. IWAMOTO Yuko (10191454)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. KITANO Motoo (10142118)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. TORII Mitsuo (30116066)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
6. ARIMURA Yuko (30222764)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. KAWAGOE Masataka (40028741)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. MINEMOTO Katashi (80200096)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. TAKADA Haruhiko (30135743)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. MARUYAMA Ikuro (20082282)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. TAMURA Masato (30236757)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. KANIE Takahito (70152791)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. TSUKADA Gakuji (70236850)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. FUJII Koichi (60156817)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. ARIKAWA Hiroyuki (90128405)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. KADOKAWA Akihiko (00169533)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. SAKUTA Tetsuya (20284888)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 斉藤弥生 (00197211)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 諏訪素子 (80206599)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

NAGAOKA Shigetaka 長岡 成孝

Research Projects

Research Products

Co-Researchers

A new culture system for studying in vitro human dental pulp repairPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification of switching factor that determinates life and death of human dental pulp cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Expression and characterization of vanilloid receptor subtype 1 in human dental pulp cell cultures.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Trial manufacture of the water jet equipment for the cavity formation and the tooth pulp removal.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Expression of enamel matrix protein in vitroPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of analyzing system for studying human dental pulp repairPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Application of vascular endothelial growth factor in conservative dentistry

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A new culture system for studying in vitro human dental pulp repairPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Possible pathogenic effect of Streptococcus mitis super antigen on oral epithelial cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

難治性根尖性歯周尖におけるインターロイキン-1,6,および8遺伝子の発現Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

根尖性歯周炎における根管浸出液および根尖部病変組織中の各種サイトカインの動態Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Cytokine induetion in severe periapical pathosis by oral anaerobes

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

感染根管歯における根管浸出液および根尖部病変組織中のインタ-ロイキンー2の動態Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

NAGAOKA Shigetaka 長岡成孝