OTSUKA Takanobu 大塚隆信

… Alternative Names

大塚隆信オオツカタカノブ

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Researcher Number	10185316
Other IDs
Affiliation (based on the past Project Information) *help	2016 – 2017: 名古屋市立大学, 大学院医学研究科, 教授 2016: 名古屋市立大学, 医学研究科, 教授 2011 – 2015: 名古屋市立大学, 医学(系)研究科(研究院), 教授 2013 – 2014: 名古屋市立大学, 大学院医学研究科, 教授 2011: 名古屋市立大学, 医学系・研究科, 教授 … More 2008 – 2009: 名古屋市立大学, 医学研究科, 教授 2007 – 2008: Nagoya City University, Graduate School of Medical Science, Professor 2005 – 2006: 名古屋市立大学, 大学院医学研究科, 教授 2002 – 2005: Nagoya City University, Graduate School of Medical Sciences, Professor, 大学院・医学研究科, 教授 2001: 名古屋市立大学, 医学部, 助教授 1995 – 2000: 名古屋市立大学, 医学部, 講師 1989 – 1990: 名古屋市立大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Orthopaedic surgery / Orthopaedic surgery Except Principal Investigator Orthopaedic surgery / Surgical dentistry / Orthopaedic surgery / Laboratory medicine / Biological Sciences
Keywords	Principal Investigator 関節リウマチ / 変形性膝関節症 / アクアポリン / rabbit / synoviocytes / rheumatoid arthritis / gliostatin / ウサギ / 慢性関節リウマチ / グリオスタチン … More / RT-PCR / 滑膜組織 / 滑膜細胞 / 関節水腫 / TGF-β / migration / PDGF-BB / heat shock protein / osteoblast / 骨粗鬆症 / 骨代謝 / HSP22 / HSP27 / Heat shock protein / 骨芽細胞 / arthroplasty / matrix metalloproteinases / thymidine phosphorylase / platelet-derived endothelial cell growth factor / Matrix metallopoteinases / 滑膜切除術 / 関節内注射 / interleukin-1β / Matrix metalloproteinases / 軟骨肉腫 / 滑膜炎 / tumor necrosis factor alpha / interleukin-8 / interleukin-6 / interleukin-1 / TNF α / TNFα / IL-8 / IL-6 / IL-1 / ヒアルロン酸 / TNF alfa / 線維芽細胞様滑膜細胞 / 関節水症 / TNF-α / 滑膜培養細胞 / アクアポリンRT-PCR / RT-PCR法 / 免疫組織化学染色 / 骨悪性腫瘍 / リポソ-ム … More Except Principal Investigator グリオスタチン / 滑膜細胞 / 関節リウマチ / synoviocytes / rheumatoid arthritis / gliostatin / DNA microarray system / 口蓋裂 / 口唇裂 / 予防 / 乳製品 / gene transfection / 血管内皮細胞増殖因子 / 血管新生 / Interleukin-1 beta / 滑膜炎 / 慢性関節リウマチ / VEGF / 脊柱変形 / 成人脊柱変形 / チミジンホスホリラーゼ / モンゴル / モンゴル人 / 温熱療法 / 疫学研究 / チーズの効果 / 先天異常の予防 / 低侵襲化 / MRI / 低侵襲手術 / パーキンソン病 / 脊柱配列 / 頚椎後弯変形 / 低侵襲脊椎手術 / DNA microarrav system / vascular endnthelial growth factor / angogenesis / Cleft Palate / Cleft Lip / Prevention / Dairy Products / Mongolian / 先天異常予防 / angiogenesis / aurothioglucose / steroid / synovitis / interleukin-1β / 金製剤 / ステロイド / matrix metalloproteinases / rabbit / thymidine phosphorylase / platelet-derived endothelial cell growth factor / 関節内注射 / ウサギ / Matrix metalloproteinases / immuno-ome / macro array / peptide chip / auto antibody / auto antigen / epitope / アレルゲン / 水疱性類天疱瘡 / アンピセンス / オーバーラップペプチド / 強皮症 / collagen / ELISA / ペプチド / イムノオーム / マクロアレイ / ペプチドチップ / 自己抗体 / 自己抗原 / エピトープ / MMP-3 / チミジンホスフォリアーゼ / TNF alfa / チミジンホスポリラーゼ / マトリックスメタロプロテイナーゼ / マトリックスメタロプロテアーゼ / FGF-2 / Osteocalcin / Osteoprotegerin / リン酸化 / ＨＳＰ27 / 翻訳 / eIF4E / オステオカルシン / 骨粗鬆症 / 骨代謝 / HSP27 / 骨芽細胞 / 脊椎固定術 / 腰痛 / 脊椎 / 脊柱 / パーキンソン / タクロリムス / カルシニューリン阻害剤 / NF-κB / クロマチン免疫沈降 / Sp1 / 細胞加温 / マグネタイト微粒子 / ナノ材料 / 癌 / 3SB細胞 / アポトーシス / 放射線治療 / ミニチュアX線源 / FE型X線源 / TE型X線源 / 培養骨・軟部肉腫 / 臨床応用 / 基礎的実験 / 放射腺療法 / 化学療法 / 悪性軟部腫瘍 / 悪性骨腫瘍 Less

multidisciplinary analysis for severe spinal deformity including cervical kyphosis
- Principal Investigator
  
  Mizutani Jun
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Nagoya City University
The molecular target of heat shock protein in bone metabolismPrincipal Investigator
- Principal Investigator
  
  Otsuka Takanobu
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Nagoya City University
Gliostatin as a novel therapeutic target for rheumatoid arthritis
- Principal Investigator
  
  NAGAYA Yuko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Nagoya City University
Safe and rigid lubosacral fixation and surgical strategy for adult spinal deformity
- Principal Investigator
  
  MIZUTANI Jun
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Nagoya City University
Aquaporins expression in fibroblast like synoviocytes from OA and RA patientsPrincipal Investigator
- Principal Investigator
  
  OTSUKA Takanobu
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Nagoya City University
Role of low-molecular-weight heat shock protein and the molecular mechanism in bone metabolism
- Principal Investigator
  
  FUKUOKA Muneyoshi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Nagoya City University
Investigation of the reasons why Mongolia has few patients with cleft lip and/or palate: the assessment of a preventive effect of dairy products
- Principal Investigator
  
  NATSUME Nagato
- Project Period (FY)
  2012 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Surgical dentistry
- Research Institution
  Aichi Gakuin University
Sp1 interference prevents joint destruction of RA through inhibitory effects of gliostatin
- Principal Investigator
  
  NAGAYA Yuko
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Nagoya City University
Study on preventive effects of intake of a large amount of dairy products by Mongolians on cleft lip/palate incidence
- Principal Investigator
  
  NATSUME Nagato
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Aichi Gakuin University
正電荷リポソーム包埋型磁性ナノ粒子を用いる温熱療法と臨床研究を目指した基盤整備
- Principal Investigator
  
  小林猛
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Chubu University
Aquaporin expression in the synovial tissues of patients with rheumatoid arthritis and osteoarthritisPrincipal Investigator
- Principal Investigator
  
  OTSUKA Takanobu
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Nagoya City University
Angiogenic action of gliostatin/thymidine phosphorylase and vascular endothelial growth factor in rheumatoid arthritis and its molecular mechanism
- Principal Investigator
  
  NAGAYA Yuko
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Nagoya City University
Investigation on Preventive Effects of Pregnancy Mongolian Large Intake of Dairy Products for Cleft Lip and/or Palate Incidence
- Principal Investigator
  
  NATSUME Nagato
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Aichi Gakuin University
ナノテクノロジーを用いた新しい放射線治療の基礎的研究
- Principal Investigator
  
  松下廉
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Nagoya City University
Angiogenic action of gliostatin in rheumatoid arthritis and its molecular mechanism
- Principal Investigator
  
  NAGAYA Yuko
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  NAGOYA CITY UNIVERSITY
水チャネル(アクアポリン)の発現からみた関節水腫発症機序の解明Principal Investigator
- Principal Investigator
  
  大塚隆信
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Nagoya City University
Arthritogenic action of gliostatin in rheumatoid arthritis and its molecular mechanism
- Principal Investigator
  
  NAGAYA Yuko
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Nagoya City University
Arthritogenic action of gliostatin in rheumatoid arthritis and its molecular mechanism.Principal Investigator
- Principal Investigator
  
  OTSUKA Takanobu
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Nagoya City University, Graduate School of Medical Sciences
Gliostatin as a clinical marker of rheumatoid arthritis and its regulation
- Principal Investigator
  
  MATSUI Nobuo
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Nagoya City University
MEDICAL APPLICATION AND DEVELOPMENT OF EPITOPE DETECTION SYSTEM TO ANTIGEN RELATED AUTO IMMUNE AND ALLERGY DISORDERS
- Principal Investigator
  
  KUNIMATSU Mitoshi
- Project Period (FY)
  1997 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Laboratory medicine
- Research Institution
  NAGOYA CITY UNIVERSITY
Gliostatin as a clinical marker of rheumatoid arthritis and its regulationPrincipal Investigator
- Principal Investigator
  
  OTSUKA Takanobu
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Nagoya City University, Medical School
抗癌剤封入リポソ-ムの作成と骨悪性腫瘍細胞に対する抗腫瘍効果の向上およびその代謝Principal Investigator
- Principal Investigator
  
  大塚隆信
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Nagoya City University
悪性骨・軟部腫瘍に対する温熱療法の基礎的実験および臨床応用に関する研究
- Principal Investigator
  
  太田弘敏
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Nagoya City University

All 2018 2017 2016 2015 2014 2013 2012 2011 2008 2007 2006 2004 2003 Other

All Journal Article Presentation Book

[Book] 達人はこうみる四肢関節画像診断関節リウマチ(RA)とRA類似疾患の画像診断2013
- Author(s)
  永谷祐子, 大塚隆信
- Publisher
  Monthly Book Orthopaedics (26 (5))
- Data Source
  KAKENHI-PROJECT-23592225
[Journal Article] Association of HSP22 with mTOR in osteoblasts: regulation of TNF-α-stimulated IL-6 synthesis2018
- Author(s)
  Sakai Go、Tokuda Haruhiko、Yamamoto Naohiro、Matsushima-Nishiwaki Rie、Fujita Kazuhiko、Kawabata Tetsu、Kozawa Osamu、Otsuka Takanobu
- Journal Title
  
  FEBS Letters
  
  Volume: 592 Issue: 7 Pages: 1202-1210
- DOI
  10.1002/1873-3468.13028
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10487, KAKENHI-PROJECT-17K11002
[Journal Article] Advantages of an on-the-screwhead crosslink connector for atlantoaxial fixation using the Goel/Harms technique2018
- Author(s)
  Mizutani Jun、Inada Atsushi、Kato Kenji、Kondo Akira、Kainuma Shingo、Fujita Kazuhiko、Yagi Kiyoshi、Shimamura Yasuteru、Fukuoka Muneyoshi、Shibamoto Yuta、Wada Ikuo、Otsuka Takanobu
- Journal Title
  
  Journal of Clinical Neuroscience
  
  Volume: 50 Pages: 183-189
- DOI
  10.1016/j.jocn.2018.01.043
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10414
[Journal Article] Suppression by HSP90 inhibitors of BMP-4-stimulated osteoprotegerin synthesis in osteoblasts: Attenuation of p70 S6 kinase2017
- Author(s)
  Kawabata Tetsu、Otsuka Takanobu、Fujita Kazuhiko、Kainuma Shingo、Yamamoto Naohiro、Kuroyanagi Gen、Sakai Go、Matsushima-Nishiwaki Rie、Kozawa Osamu、Tokuda Haruhiko
- Journal Title
  
  Molecular Medicine Reports
  
  Volume: 16 Issue: 6 Pages: 8507-8512
- DOI
  10.3892/mmr.2017.7639
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10487
[Journal Article] HSP90 inhibitors potentiate PGF2α-induced IL-6 synthesis via p38 MAP kinase in osteoblasts2017
- Author(s)
  Fujita Kazuhiko、Tokuda Haruhiko、Kuroyanagi Gen、Yamamoto Naohiro、Kainuma Shingo、Kawabata Tetsu、Sakai Go、Matsushima-Nishiwaki Rie、Kozawa Osamu、Otsuka Takanobu
- Journal Title
  
  PLOS ONE
  
  Volume: 12 Issue: 5 Pages: e0177878-e0177878
- DOI
  10.1371/journal.pone.0177878
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10487
[Journal Article] Heat shock protein 70 negatively regulates TGF-β-stimulated VEGF synthesis via p38 MAP kinase in osteoblasts.2017
- Author(s)
  Sakai G, Tokuda H, Fujita K, Kainuma S, Kawabata T, Matsushima-Nishiwaki R, Kozawa O, Otsuka T.
- Journal Title
  
  Cell. Physiol. Biochem.
  
  Volume: 44 Issue: 3 Pages: 1133-1145
- DOI
  10.1159/000485418
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11002, KAKENHI-PROJECT-15K10487
[Journal Article] Heat shock protein 27 (HSPB1) suppresses the PDGF-BB-induced migration of osteoblasts2017
- Author(s)
  Kainuma Shingo、Tokuda Haruhiko、Yamamoto Naohiro、Kuroyanagi Gen、Fujita Kazuhiko、Kawabata Tetsu、Sakai Go、Matsushima-Nishiwaki Rie、Kozawa Osamu、Otsuka Takanobu
- Journal Title
  
  International Journal of Molecular Medicine
  
  Volume: 40 Issue: 4 Pages: 1057-1066
- DOI
  10.3892/ijmm.2017.3119
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10487
[Journal Article] Regulation by AMP-activated protein kinase of PGE2-induced osteoprotegerin synthesis in osteoblasts.2016
- Author(s)
  Kainuma S, Otsuka T, Kuroyanagi G, Yamamoto N, Matsushima-Nishiwaki R, Kozawa O and Tokuda H.
- Journal Title
  
  Mol Med Rep.
  
  Volume: 4 Issue: 4 Pages: 3363-3369
- DOI
  10.3892/mmr.2016.4900
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26462289, KAKENHI-PROJECT-26462309
[Journal Article] Thrombin Receptor-Activating Protein (TRAP)-Activated Akt Is Involved in the Release of Phosphorylated-HSP27 (HSPB1) from Platelets in DM Patients.2016
- Author(s)
  Tokuda H, Kuroyanagi G, Tsujimoto M, Matsushima-Nishiwaki R, Akamatsu S, Enomoto Y, Iida H, Otsuka T, Ogura S, Iwama T, Kojima K, Kozawa O.
- Journal Title
  
  Int J Mol Sci
  
  Volume: 17 Issue: 5 Pages: 737-737
- DOI
  10.3390/ijms17050737
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26462309, KAKENHI-PROJECT-26462335, KAKENHI-PROJECT-15K10509
[Journal Article] Heat shock protein 22 (HSPB8) limits TGF-β-stimulated migration of osteoblasts.2016
- Author(s)
  Yamamoto N, Tokuda H, Kuroyanagi G, Kainuma S, Matsushima-Nishiwaki R, Fujita K, Kozawa O, Otsuka T.
- Journal Title
  
  Mol Cell Endocrinol
  
  Volume: 436 Pages: 1-9
- DOI
  10.1016/j.mce.2016.07.011
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462309, KAKENHI-PROJECT-15K10487
[Journal Article] Possible involvement of AMP-activated protein kinase in PGE(1)-induced synthesis of osteoprotegerin in osteoblasts.2016
- Author(s)
  Kainuma S, Otsuka T, Kuroyanagi G, Yamamoto N, Matsushima-Nishiwaki R, Kozawa O, Tokuda H.
- Journal Title
  
  Exp Ther Med
  
  Volume: 11 Pages: 2042-2048
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26462309
[Journal Article] Resveratrol reduces prostaglandin E1-stimulated osteoprotegerin synthesis in osteoblasts: Suppression of stress-activated protein kinase/c-Jun N-terminal kinase.2015
- Author(s)
  Yamamoto N, Otsuka T, Kuroyanagi G, Kondo A, Kainuma S, Nakakami A, Matsushima-Nishiwaki R, Kozawa O, Tokuda H.
- Journal Title
  
  Prostaglandins Other Lipid Mediat.
  
  Volume: 116-117 Pages: 57-63
- DOI
  10.1016/j.prostaglandins.2015.01.003
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24592273
[Journal Article] Quantitative analysis of attachment of the labrum to the glenoid fossa: a cadaveric study.2015
- Author(s)
  Yoshida M, Goto H, Nozaki M, Nishimori Y, Takenaga T, Murase A, Nagaya Y, Iguchi H, Kobayashi M, Sugimoto K, Nishiyama T, Otsuka T.
- Journal Title
  
  J Orthop Sci
  
  Volume: 20 Issue: 5 Pages: 823-829
- DOI
  10.1007/s00776-015-0742-4
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26462309
[Journal Article] Unphosphorylated HSP27 (HSPB1) regulates the translation initiation process via a direct association with eIF4E in osteoblasts.2015
- Author(s)
  Kuroyanagi G, Tokuda H, Yamamoto N, Matsushima-Nishiwaki R, Kozawa O, Otsuka T
- Journal Title
  
  Int J Mol Med
  
  Volume: 36 Issue: 3 Pages: 881-889
- DOI
  10.3892/ijmm.2015.2274
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26462309
[Journal Article] Rac limits TGF-β-induced VEGF synthesis in osteoblasts. Mol Cell Endocrinol.2015
- Author(s)
  Yamamoto N, Otsuka T, Kondo A, Matsushima-Nishiwaki R, Kuroyanagi G, Kozawa O, Tokuda H.
- Journal Title
  
  Mol Cell Endocrinol
  
  Volume: 405 Pages: 35-41
- DOI
  10.1016/j.mce.2015.02.002
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24592272, KAKENHI-PROJECT-24592273
[Journal Article] Rho-kinase regulates human platelet activation induced by thromboxane A2 independently of p38 MAP kinase.2015
- Author(s)
  Iida Y, Doi T, Tokuda H, Matsushima-Nishiwaki R, Tsujimoto M, Kuroyanagi G, Yamamoto N, Enomoto Y, Tanabe K, Otsuka T, Iwama T, Ogura S, Kozawa O, Iida H.
- Journal Title
  
  Prostaglandins Leukot Essent Fatty Acids.
  
  Volume: 94 Pages: 73-81
- DOI
  10.1016/j.plefa.2014.11.006
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24592273, KAKENHI-PROJECT-24592294, KAKENHI-PROJECT-26462334
[Journal Article] Resveratrol suppresses TGF-β-induced VEGF synthesis in osteoblasts: Inhibition of the p44/p42 MAPKs and SAPK/JNK pathways.2015
- Author(s)
  Kuroyanagi G, Otsuka T, Yamamoto N, Matsushima-Nishiwaki R, Kozawa O, Tokuda H.
- Journal Title
  
  Exp Ther Med
  
  Volume: 9 Issue: 6 Pages: 2303-2310
- DOI
  10.3892/etm.2015.2389
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26462309
[Journal Article] Postoperative evaluation of drill holes for arthroscopic Bankart repair with suture anchors by the use of computed tomography.2015
- Author(s)
  Yoshida M, Goto H, Nozaki M, Nishimori Y, Takenaga T, Murase A, Nagaya Y, Iguchi H, Kobayashi M, Sugimoto K, Otsuka T.
- Journal Title
  
  J Orthop Sci
  
  Volume: 20 Issue: 3 Pages: 481-487
- DOI
  10.1007/s00776-015-0703-y
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26462309
[Journal Article] New Protocol to Optimize iPS Cells for Genome Analysis of Fibrodysplasia Ossificans Progressiva.2015
- Author(s)
  Matsumoto Y, Ikeya M, Hino K, Horigome K, Fukuta M, Watanabe M, Nagata S, Yamamoto T, Otsuka T, Toguchida J.
- Journal Title
  
  Stem Cells.
  
  Volume: 印刷中 Issue: 6 Pages: 1730-1742
- DOI
  10.1002/stem.1981
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25293320, KAKENHI-PROJECT-26462309, KAKENHI-PROJECT-15K15549
[Journal Article] αB-crystallin reduces ristocetin‑induced soluble CD40 ligand release in human platelets: Suppression of thromboxane A2 generation.2015
- Author(s)
  Tsujimoto M, Doi T, Kuroyanagi G, Yamamoto N, Matsushima-Nishiwaki R, Iida Y, Enomoto Y, Iida H, Ogura S, Otsuka T, Tokuda H, Kozawa O, Iwama T.
- Journal Title
  
  Mol Med Rep.
  
  Volume: 12(1) Issue: 1 Pages: 357-362
- DOI
  10.3892/mmr.2015.3445
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24592273
[Journal Article] Derivation of mesenchymal stromal cells from pluripotent stem cells through a neural crest lineage using small molecule compounds with defined media.2014
- Author(s)
  Fukuta M, Nakai Y, Kirino K, Nakagawa M, Sekiguchi K, Nagata S, Matsumoto Y, Yamamoto T, Umeda K, Heike T, Okumura N, Koizumi N, Sato T, Nakahata T, Saito M, Otsuka T, Kinoshita S, Ueno M, Ikeya M, Toguchida J.
- Journal Title
  
  PLOS ONE
  
  Volume: 9 Issue: 12 Pages: e112291-e112291
- DOI
  10.1371/journal.pone.0112291
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390353, KAKENHI-PROJECT-24590353, KAKENHI-PROJECT-24592272, KAKENHI-PROJECT-25293320, KAKENHI-PROJECT-25461591, KAKENHI-PROJECT-26253062, KAKENHI-PROJECT-26670498
[Journal Article] Resveratrol inhibits BMP-4-stimulated VEGF synthesis in osteoblasts: suppression of S6 kinase.2014
- Author(s)
  Kondo A, Otsuka T, Kuroyanagi G, Yamamoto N, Matsushima-Nishiwaki R, Mizutani J, Kozawa O, Tokuda H.
- Journal Title
  
  Int J Mol Med.
  
  Volume: 33(4) Issue: 4 Pages: 1013-1018
- DOI
  10.3892/ijmm.2014.1626
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24592273, KAKENHI-PROJECT-26462309
[Journal Article] Suppression by resveratrol of prostaglandin D2-stimulated osteoprotegerin synthesis in osteoblasts.2014
- Author(s)
  Kuroyanagi G, Mizutani J, Kondo A, Yamamoto N, Matsushima-Nishiwaki R, Otsuka T, Kozawa O, Tokuda H.
- Journal Title
  
  Prostaglandins Leukot Essent Fatty Acids.
  
  Volume: S0952-3278(14) Issue: 3 Pages: 72-76
- DOI
  10.1016/j.plefa.2014.04.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592273, KAKENHI-PROJECT-26462309
[Journal Article] Involvement of Rac in thromboxane A2-induced human platelet activation: Regulation of sCD40 ligand release and PDGF-AB secretion.2014
- Author(s)
  Kageyama Y, Doi T, Matsushima-Nishiwaki R, Iida Y, Akamatsu S, Kondo A, Kuroyanagi G, Yamamoto N, Mizutani J, Otsuka T, Tokuda H, Iida H, Kozawa O, Ogura S.
- Journal Title
  
  Mol Med Rep.
  
  Volume: 10(1) Issue: 1 Pages: 107-12
- DOI
  10.3892/mmr.2014.2143
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592273, KAKENHI-PROJECT-24592294, KAKENHI-PROJECT-26462335
[Journal Article] Resveratrol suppresses prostaglandin F(2α)-induced osteoprotegerin synthesis in osteoblasts: inhibition of the MAP kinase signaling.2014
- Author(s)
  Kuroyanagi G, Tokuda H, Matsushima-Nishiwaki R, Kondo A, Mizutani J, Kozawa O, Otsuka T.
- Journal Title
  
  Arch Biochem Biophys.
  
  Volume: 542 Pages: 39-45
- DOI
  10.1016/j.abb.2013.12.002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24592273, KAKENHI-PROJECT-26462289
[Journal Article] Down-regulation by resveratrol of basic fibroblast growth factor-stimulated osteoprotegerin synthesis through suppression of Akt in osteoblasts.2014
- Author(s)
  Kuroyanagi G, Otsuka T, Yamamoto N, Matsushima-Nishiwaki R, Nakakami A, Mizutani J, Kozawa O, Tokuda H.
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 15(10) Issue: 10 Pages: 17886-17900
- DOI
  10.3390/ijms151017886
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24592273
[Journal Article] Down-regulation by resveratrol of basic fibroblast growth factor-stimulated osteoprotegerin synthesis through suppression of Akt in osteoblasts.2014
- Author(s)
  Kuroyanagi G, Otsuka T, Yamamoto N, Matsushima-Nishiwaki R, Nakakami A, Mizutani J, Kozawa O, Tokuda H.
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 15 Issue: 5 Pages: 17886-900
- DOI
  10.3892/ijmm.2014.1934
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24592272, KAKENHI-PROJECT-24592273
[Journal Article] Rho-kinase limits BMP-4-stimulated osteocalcin synthesis in osteoblasts: regulation of the p38 MAP kinase pathway.2014
- Author(s)
  Kondo A, Tokuda H, Matsushima-Nishiwaki R, Kuroyanagi G, Yamamoto N, Mizutani J, Kozawa O, Otsuka T.
- Journal Title
  
  Life Sci.
  
  Volume: 96(1-2) Issue: 1-2 Pages: 18-25
- DOI
  10.1016/j.lfs.2013.12.017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592273
[Journal Article] Progression of hip joint deformity during the management of pelvic insufficiency fracture in a patient with rheumatoid arthritis: a case report.2014
- Author(s)
  Ikuta K, Waguri-Nagaya Y, Nozaki M, Mizutani J, Goto H, Kobayashi M, Otsuka T.
- Journal Title
  
  J Spine
  
  Volume: 3 Issue: 05 Pages: 6-6
- DOI
  10.4172/2165-7939.1000188
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26462309
[Journal Article] Cigarette smoke condensate extracts induce IL-1beta production from rheumatoid arthritis patient-derived synoviocytes, but not osteoarthritis patient-derived synoviocytes, through aryl hydrocarbon receptor-dependent NF-kappa B activation and novel NF-kappa B sites.2013
- Author(s)
  Adachi M, Okamoto S, Chujyo S, Arakawa T, Yokoyama M, Yamada K, Hayashi A, Akita K, Takeno M, Ito S, Takii T, Waguri-Nagaya Y, Otsuka T, Hayakawa K, Miyazawa K, Onozaki K.
- Journal Title
  
  J Interferon & Cytokine Research
  
  Volume: March
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592272
[Journal Article] Identification of target genes of synovial sarcoma-associated fusion oncoprotein using human pluripotent stem cells.2013
- Author(s)
  Hayakawa K, Ikeya M, Fukuta M, Woltjen K, Tamaki S, Takahara N, Kato T Jr, Sato S, Otsuka T, Toguchida J
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 432 Issue: 4 Pages: 713-719
- DOI
  10.1016/j.bbrc.2013.01.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592272, KAKENHI-PROJECT-24659133
[Journal Article] Thrombopoietin amplifies ADP-induced HSP27 phosphorylation in human platelets: importance of its pre-treatment.2013
- Author(s)
  Cuong TN, Doi T, Matsushima-Nishiwaki R, Akamatsu S, Kuroyanagi G, Kondo A, Mizutani J, Wada I, Otsuka T, Tokuda H, Kozawa O, Ogura S.
- Journal Title
  
  J. Mol. Med.
  
  Volume: 31 Issue: 6 Pages: 1291-1297
- DOI
  10.3892/ijmm.2013.1345
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592249, KAKENHI-PROJECT-24592273
[Journal Article] (-)-Epigallocatechin gallate amplifies interleukin-1-stimulated interleukin-6 synthesis in osteoblast-like MC3T3-E1 cells.2013
- Author(s)
  Kuroyanagi G, Otsuka T, Kondo A, Matsushima-Nishiwaki R, Mizutani J, Kozawa O, Tokuda H.
- Journal Title
  
  Biochimie.
  
  Volume: 95(10) Issue: 10 Pages: 1933-1938
- DOI
  10.1016/j.biochi.2013.07.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592273
[Journal Article] Cigarette smoke condensate extracts induce IL-1 beta production from rheumatoid arthritis patient-derived synoviocytes, but not osteoarthritis patient-derived synoviocytes, through aryl hydrocarbon receptor-dependent NF-kappa B activation and novel NF-kappa B sites.2013
- Author(s)
  Adachi M, Okamoto S, Chujyo S, Arakawa T, Yokoyama M, Yamada K, Hayashi A, Akita K, Takeno M, Ito S, Takii T, Waguri-Nagaya Y, Otsuka T, Hayakawa K, Miyazawa K, Onozaki K.
- Journal Title
  
  J Interferon & Cytokine Research
  
  Volume: 33 Issue: 6 Pages: 297-307
- DOI
  10.1089/jir.2012.0107
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592225, KAKENHI-PROJECT-24592272, KAKENHI-PROJECT-25460171
[Journal Article] Unphosphorylated HSP27 plays a suppressive role in FGF-2-stimulated VEGF release in osteoblasts.2013
- Author(s)
  Kondo A, Tokuda H, Matsushima-Nishiwaki R, Kato K, Kuroyanagi G, Mizutani J, Fukuoka M, Wada I, Kozawa O, Otsuka T.
- Journal Title
  
  Mol. Med. Rep.
  
  Volume: 7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592273
[Journal Article] Rho-kinase negatively regulates thyroid hormone-stimulated osteocalcin synthesis in osteoblasts.2013
- Author(s)
  Kondo A, Tokuda H, Kato K, Matsushima-Nishiwaki R, Kuroyanagi G, Mizutani J, Kozawa O, Otsuka T.
- Journal Title
  
  Biochimie
  
  Volume: 95 Issue: 4 Pages: 719-24
- DOI
  10.1016/j.biochi.2012.10.020
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592272, KAKENHI-PROJECT-24592273
[Journal Article] AMP-activated protein kinase regulates thyroid hormone-stimulated osteocalcin synthesis in osteoblasts.2013
- Author(s)
  Kondo A, Otsuka T, Kato K, Matsushima-Nishiwaki R, Kuroyanagi G, Mizutani J, Tokuda H, Kozawa O.
- Journal Title
  
  Int J Mol Med.
  
  Volume: 31(6) Issue: 6 Pages: 1457-62
- DOI
  10.3892/ijmm.2013.1349
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592273
[Journal Article] Rac regulates collagen-induced HSP27 phosphorylation via p44/p42 MAP kinase in human platelets.2013
- Author(s)
  Kageyama Y, Doi T, Akamatsu S, Kuroyanagi G, Kondo A, Mizutani J, Otsuka T, Tokuda H, Kozawa O, Ogura S.
- Journal Title
  
  Int. J. Mol. Med.
  
  Volume: 32 Issue: 4 Pages: 813-818
- DOI
  10.3892/ijmm.2013.1455
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592249, KAKENHI-PROJECT-24592273
[Journal Article] Inhibition of SAPK/JNK leads to enhanced IL-1-induced IL-6 synthesis in osteoblasts.2013
- Author(s)
  Kondo A, Otsuka T, Matsushima-Nishiwaki R, Kuroyanagi G, Mizutani J, Wada I, Kozawa O, Tokuda H.
- Journal Title
  
  Arch Biochem Biophys.
  
  Volume: 535(2) Issue: 2 Pages: 227-33
- DOI
  10.1016/j.abb.2013.04.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592273
[Journal Article] Unphosphorylated heat shock protein 27 suppresses fibroblast growth factor-2-stimulated vascular endothelial growth factor release in osteoblasts.2013
- Author(s)
  Kondo A, Tokuda H, Matsushima-Nishiwaki R, Kato K, Kuroyanagi G, Mizutani J, Fukuoka M, Wada I, Kozawa O, Otsuka T.
- Journal Title
  
  Mol Med Rep
  
  Volume: 8 Issue: 2 Pages: 691-695
- DOI
  10.3892/mmr.2013.1533
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592272, KAKENHI-PROJECT-24592273
[Journal Article] AMP-activated protein kinase regulates PDGF-BB-stimulated interleukin-6 synthesis in osteoblasts: involvement of mitogen-activated protein kinases.2012
- Author(s)
  Kato K, Otsuka T, Kondo A, Matsushima-Nishiwaki R, Natsume H, Kozawa O, Tokuda H.
- Journal Title
  
  Life Sci.
  
  Volume: 90 Issue: 1-2 Pages: 71-76
- DOI
  10.1016/j.lfs.2011.10.023
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592273
[Journal Article] AMP-activated protein kinase inhibitor decreases prostaglandin F2α-stimulated interleukin-6 synthesis through p38 MAP kinase in osteoblasts.2012
- Author(s)
  Kondo A, Otsuka T, Kato K, Natsume H, Kuroyanagi G, Mizutani J, Ito Y, Matsushima-Nishiwaki R, Kozawa O, Tokuda H.
- Journal Title
  
  Int. J. Mol. Med.
  
  Volume: 30 Issue: 6 Pages: 1487-1492
- DOI
  10.3892/ijmm.2012.1159
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592273
[Journal Article] Wnt3a upregulates prostaglandin F2α-stimulated vascular endothelial growth factor　synthesis in osteoblasts.2012
- Author(s)
  Kondo A, Tokuda H, Mizutani J, Matsushima-Nishiwaki R, Kozawa O, Otsuka T.
- Journal Title
  
  Mol Med Report.
  
  Volume: 6 Issue: 2 Pages: 421-425
- DOI
  10.3892/mmr.2012.916
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592272, KAKENHI-PROJECT-24592273
[Journal Article] The Sp1 transcription factor is essential for the expression of gliostatin/thymidine phosphorylase in rheumatoid fibroblast-like synoviocytes.2012
- Author(s)
  Ikuta K, Waguri-Nagaya Y, Kikuchi K, Yamagami T, Nozaki M, Aoyama M, Asai K,Otsuka T.
- Journal Title
  
  Arthritis Res Ther.
  
  Volume: 14 Issue: 2
- DOI
  10.1186/ar3811
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591165, KAKENHI-PROJECT-23591509, KAKENHI-PROJECT-23592225, KAKENHI-PROJECT-24592272
[Journal Article] Involvement of AMP-activated protein kinase in thrombin-stimulated interleukin-6 synthesis in osteoblasts.2012
- Author(s)
  Tokuda H, Kato K, Natsume H, Kondo A, Kuroyanagi G, Matsushima-Nishiwaki R, Ito Y, Otsuka T, Kozawa O.
- Journal Title
  
  J. Mol. Endocrinol.
  
  Volume: 49 Issue: 1 Pages: 47-55
- DOI
  10.1530/jme-11-0165
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592273
[Journal Article] Comparative risk of common peroneal nerve injury in far anteromedial portal drilling and transtibial drilling in anatomicaldouble-bundle ACL reconstruction.2012
- Author(s)
  Otani M, Nozaki M, Kobayashi M, Goto H, Tawada K, Waguri-Nagaya Y, Okamoto H, Iguchi H, Watanabe N, Otsuka T.
- Journal Title
  
  Knee Surg Sports Traumatol Arthrosc
  
  Volume: 20 Issue: 5 Pages: 838-843
- DOI
  10.1007/s00167-011-1632-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592225
[Journal Article] Involvement of AMP-activated protein kinase in TGF-α-stimulated VEGF synthesis in osteoblasts.2012
- Author(s)
  Mizutani J, Tokuda H, Matsushima-Nishiwaki R, Kato K, Kondo A, Natsume H, Kozawa O, Otsuka T.
- Journal Title
  
  Int. J. Mol. Med.
  
  Volume: 29 Issue: 4 Pages: 550-556
- DOI
  10.3892/ijmm.2012.893
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592273
[Journal Article] AMPK limits IL-1-stimulated IL-6 synthesis in osteoblasts: involvement of IκB/NF-κB pathway.2012
- Author(s)
  Kato K, Tokuda H, Matsushima-Nishiwaki R, Natsume H, Kondo A, Ito Y, Kozawa O,　Otsuka T.
- Journal Title
  
  Cell Signal
  
  Volume: 24 Issue: 8 Pages: 1706-1712
- DOI
  10.1016/j.cellsig.2012.04.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592272, KAKENHI-PROJECT-24592273
[Journal Article] FK506 inhibition of gliostatin/thymidine phosphorylase production induced by tumor necrosis factor-α in rheumatoid fibroblast-like synoviocytes.2011
- Author(s)
  T Yamagami, Waguri-Nagaya Y, Ikuta K, Aoyama M, Asai K, Otsuka T.
- Journal Title
  
  Rheumatol Int (Clinical and Experimental Investigations)
  
  Volume: 37 Pages: 903-909
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592225
[Journal Article] Comparative risk of common peroneal nerve injury in far anteromedial portal drilling and transtibial drilling in anatomicaldouble-bundle ACL reconstruction.2011
- Author(s)
  Otani M, Nozaki M, Kobayashi M, Goto H, Tawada K, Waguri-Nagaya Y, Okamoto H, Iguchi H, Watanabe N, Otsuka T.
- Journal Title
  
  Knee Surg Sports Traumatol Arthrosc
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592225
[Journal Article] FK506inhibition of gliostatin/thymidine phosphorylase production induced by tumornecrosis factor-α in rheumatoid fibroblast-like synoviocytes.2011
- Author(s)
  Yamagami T, Waguri-Nagaya Y, Ikuta K, Aoyama M, Asai K, Otsuka T.
- Journal Title
  
  Rheumatol Int.
  
  Volume: 31 Issue: 7 Pages: 903-9
- DOI
  10.1007/s00296-010-1411-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591165, KAKENHI-PROJECT-23592225
[Journal Article] Arthroscopic synovectomy of the metacarpophalangeal and proximal interphalangeal joints2008
- Author(s)
  Sekiya I, Kobayashi M, Okamoto H, Iguchi H, Waguri-Nagaya Y, Goto H, Nozaki M, Tsuchiya A, Otsuka T.
- Journal Title
  
  Tech Hand Up Extrem Surg 12
  
  Pages: 221-225
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591760
[Journal Article] Dihydrotestosterone inhibits tumor necrosis factor alpha induced interleukin-1alpha mRNA expression in rheumatoid fibroblast-like synovial cells2007
- Author(s)
  Itoh Y, Hayashi H, Xu J, Takii T, Miyazawa K, Ariga H, Akahoshi T, Waguri-Nagaya Y, Otsuka T, Okamoto T, Onozaki K.
- Journal Title
  
  Biol Pharm Bull 30
  
  Pages: 1140-1143
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591760
[Journal Article] Gliostatin/thymidine phosphorylase-regulated vascular endothelial growth-factor production in human fibroblast-like synoviocytes2007
- Author(s)
  Tanikawa, T, Waguri-Nagava, Y, Kusabe, T, Aoyama, M, Asai, K, Otsuka, T
- Journal Title
  
  Rheumatol Int 27
  
  Pages: 553-559
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591670
[Journal Article] Gliostatin/ thymidine phosphorylase-regulated vascular endothelial growth- factor production in human fibroblast-like synoviocytes2007
- Author(s)
  Tanikawa T, Waguri-Nagaya Y, Kusabe T, Aoyama M, Asai K, Otsuka T.
- Journal Title
  
  Rheumatol Int 27
  
  Pages: 553-559
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591760
[Journal Article] Septic arthritis of the right ankle caused by Staphylococcus aureus infection in a rheumatoid arthritis patient treated with etanercept2007
- Author(s)
  Waguri-Nagaya Y, Kobayashi M, Goto H, Hisazaki S, Tsuchiya A, Otsuka T.
- Journal Title
  
  Mod Rheumatol 17
  
  Pages: 338-340
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591760
[Journal Article] Dihydrotestosterone inhibits tumor necrosis factor alpha induced interleukin-lalpha mRNA expression in rheumatoid fibroblast-like synovial cells2007
- Author(s)
  Itoh, Y, Hayashi, H, Xu, J, Takii, T, Miyazawa, K, Ariga, H, Akahoshi, T, Waguri-Nagava, Y, Otsuka, T, Okamoto, T, Onozaki, K
- Journal Title
  
  Biol Pharm Bull 30
  
  Pages: 1140-1143
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591670
[Journal Article] Fate of transplanted nail matrical cells and potential of hard keratin production in vivo2006
- Author(s)
  Okamoto, H, Kagami, H, Okada, K, Ito, Y, Sekiya, I, Waguri-Nagava, Y, Ogikubo, O, Ueda, M, Otsuka, T
- Journal Title
  
  J Dermatol Sci 44
  
  Pages: 175-8
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591670
[Journal Article] Neuropathic arthropathy caused by chondrosarcoma of the cervical spine. A case report.2004
- Author(s)
  Waguri-Nagaya Y, Otsuka T, et al.
- Journal Title
  
  Mod Rheumatol 14
  
  Pages: 160-163
- Data Source
  KAKENHI-PROJECT-15659357
[Journal Article] Neuropathic arthropathy caused by chondrosarcoma of the cervical spine. A case report.2004
- Author(s)
  Waguri-Nagaya Y, Otsuka T, et al.
- Journal Title
  
  Mod Rheumatol 14
  
  Pages: 160-163
- Data Source
  KAKENHI-PROJECT-16591504
[Journal Article] NF-kappa B p65 transactivation domain is involved in the NF-kappa B-inducing kinase pathway.2003
- Author(s)
  Jiang X, Otsuka T, et al.
- Journal Title
  
  BBRC 301
  
  Pages: 583-590
- Data Source
  KAKENHI-PROJECT-15659357
[Journal Article] Inhibition of recombinant dipeptidyl peptidase III by synthetic hemorphin-like peptides.2003
- Author(s)
  Chiba T, Otsuka T, et al.
- Journal Title
  
  Peptides 24
  
  Pages: 773-778
- Data Source
  KAKENHI-PROJECT-15659357
[Journal Article] RAにおける滑膜切除術の意義膝関節に対する鏡視下滑膜切除術の意義2003
- Author(s)
  小林正明, 永谷祐子, 大塚隆信, 他
- Journal Title
  
  整形・災害外科 46
  
  Pages: 37-44
- Data Source
  KAKENHI-PROJECT-15659357
[Journal Article] Silicone-induced foreign-body reaction after first metatarsophalangeal joint arthroplasty for Jaccoud's arthropathy
- Author(s)
  Waguri-Nagaya Y, Yamagami T, Tsuchiya A, Nozaki M, Goto H, Kobayashi M, Aoyama M, T. Tada T, Otsuka T.
- Journal Title
  
  Rheumatology International (Clinical and Experimental Investigations) (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591760
[Presentation] 重度頚椎後弯変形再建術後の全脊柱バランスの変化2017
- Author(s)
  水谷潤、鐙邦芳、石井賢、八木満、遠藤健司、大塚隆信、和田郁雄、C.Ames
- Organizer
  第90回日本整形外科学会学術総会
- Place of Presentation
  仙台国際センター他（宮城県、仙台市）
- Year and Date
  2017-05-18
- Data Source
  KAKENHI-PROJECT-15K10414
[Presentation] 重度頚椎後弯変形再建術後の全脊柱バランスの変化2017
- Author(s)
  水谷潤、鐙邦芳、石井賢、八木満、遠藤健司、大塚隆信、和田郁雄、 C.Ames
- Organizer
  第90回日本整形外科学会学術総会
- Data Source
  KAKENHI-PROJECT-15K10414
[Presentation] 頚椎後弯変形における全脊柱バランストと頭蓋ポジション2017
- Author(s)
  水谷潤、遠藤健司、鐙邦芳、石井賢、八木満、細金直文、大塚隆信、和田郁雄、C.Ames
- Organizer
  第90回日本整形外科学会学術総会
- Place of Presentation
  仙台国際センター他（宮城県、仙台市）
- Year and Date
  2017-05-18
- Data Source
  KAKENHI-PROJECT-15K10414
[Presentation] 頚椎後弯変形における全脊柱バランストと頭蓋ポジション2017
- Author(s)
  水谷潤、遠藤健司、鐙邦芳、石井賢、八木満、細金直文、大塚隆信、和田郁雄、C.Ames
- Organizer
  第90回日本整形外科学会学術総会
- Data Source
  KAKENHI-PROJECT-15K10414
[Presentation] Sp1 interference prevents joint destruction of RA through inhibitory effects of gliostatin and matrix metalloproteinase-3.2016
- Author(s)
  Ikuta K, Kawaguchi Y, Waguri-Nagaya Y, Tatematsu N, Kobayashi M, Goto H, Nozaki M, Aoyama M, Asai K, Otsuka T.
- Organizer
  Annual European Congress of Rheumatology (EULAR2016)
- Place of Presentation
  ExCel London, London, United Kingdom)
- Year and Date
  2016-06-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462309
[Presentation] The JAK inhibitor (Tofacitinib) inhibits TNF-induced gliostatin/thymidine phosphorylase expression in human fibroblast-like synoviocytes.2016
- Author(s)
  Kawaguchi Y, Waguri-Nagaya Y, Tatematsu N, Kobayashi M, Goto H, Nozaki M, Ikuta K, Aoyama M, Asai K, Otsuka T.
- Organizer
  Annual European Congress of Rheumatology (EULAR2016)
- Place of Presentation
  ExCel London, London (United Kingdom)
- Year and Date
  2016-06-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462309
[Presentation] Sp1 inhibitor modulates the autocrine action of gliostatin/thymidine phosphorylase (GLS/TYMP) in rheumatoid fibroblast-like synoviocytes.2016
- Author(s)
  Tatematsu N, Waguri-Nagaya Y, Kawaguchi Y, Ikuta K, Kobayashi M, Goto H, Nozaki M, Aoyama M, Asai K, Otsuka T.
- Organizer
  Annual European Congress of Rheumatology (EULAR2016)
- Place of Presentation
  ExCel London, London (United Kingdom)
- Year and Date
  2016-06-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462309
[Presentation] Sp1 inhibitor modulates the autocrine action of gliostatin/thymidine phosphorylase (GLS/TYMP) in rheumatoid fibroblast-like synoviocytes.2016
- Author(s)
  Tatematsu N, Waguri-Nagaya Y, Kawaguchi Y, Ikuta K, Kobayashi M, Goto H, Nozaki M, Aoyama M, Asai K, Otsuka T.
- Organizer
  Annual European Congress of Rheumatology (EULAR2016)
- Place of Presentation
  ExCel London, London, United Kingdom)
- Year and Date
  2016-06-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462309
[Presentation] 関節リウマチ患者の血清 N-acetyl-seryl-aspartyl-lysyl-proline(AcSDKP) 濃度は治療の有効性を反映している.2016
- Author(s)
  立松尚衞, 永谷祐子, 川口洋平, 井之上浩一, 浅井清文, 大塚隆信.
- Organizer
  第89回日本整形外科学会学術集会
- Place of Presentation
  パシフィコ横浜, 横浜
- Year and Date
  2016-05-12
- Data Source
  KAKENHI-PROJECT-26462309
[Presentation] グリオスタチン発現抑制はリウマチ滑膜細胞に対するJAK阻害剤の新規作用機序である.2016
- Author(s)
  川口洋平, 永谷祐子, 立松尚衞, 小林正明, 後藤英之, 野崎正浩, 青山峰芳, 浅井清文, 大塚隆信.
- Organizer
  第31回日本整形外科基礎学術集会
- Place of Presentation
  福岡国際会議場 (福岡県, 福岡市)
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-26462309
[Presentation] Relationship between psoas muscle position and spin-pelvic parameters: an analysis using magnetic resonance imaging2016
- Author(s)
  Akira Kondo, Yuichiro Abe, Jun Mizutani, Shigenobu Sato, Kentaro Yamada, Takanobu Otsuka
- Organizer
  9th Annual SOLAS research meeting
- Place of Presentation
  San Diego, USA
- Year and Date
  2016-03-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10414
[Presentation] 関節リウマチ線維芽細胞様滑膜細胞においてTNF alfaによるグリオスタチンの発現は JAK阻害剤により抑制される.2016
- Author(s)
  川口洋平, 永谷祐子, 小林正明, 後藤英之, 野崎正浩, 青山峰芳, 浅井清文, 大塚隆信.
- Organizer
  第160回名古屋市立大学医学会例会.
- Place of Presentation
  名古屋市立大学大学院医学研究科研究棟 (愛知県 .名古屋市)
- Year and Date
  2016-06-20
- Data Source
  KAKENHI-PROJECT-26462309
[Presentation] トファシチニブ投与RA患者の臨床像と血清グリオスタチンへの影響の検討.2016
- Author(s)
  川口洋平, 永谷祐子, 立松尚衛, 小林正明, 後藤英之, 野崎正浩, 小栗雄介, 浅井清文, 大塚隆信.
- Organizer
  第60回日本リウマチ学会総会・学術集会.
- Place of Presentation
  パシフィコ横浜 (神奈川県, 横浜市)
- Year and Date
  2016-04-21
- Data Source
  KAKENHI-PROJECT-26462309
[Presentation] 関節リウマチ線維芽細胞様滑膜細胞に置いてグリオスタチンによって誘導されたMMPsはSp１阻害剤によって抑制される.2016
- Author(s)
  立松尚衞, 永谷祐子, 川口洋平, 生田憲史, 小栗雄介, 小林正明,野崎正浩, 青山峰芳, 浅井清文, 大塚隆信.
- Organizer
  第31回日本整形外科基礎学術集会
- Place of Presentation
  福岡国際会議場 (福岡県, 福岡市)
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-26462309
[Presentation] 関節リウマチ患者の血清 N-acetyl-seryl-aspartyl-lysyl-proline(AcSDKP) 濃度は治療の有効性を反映している.2016
- Author(s)
  立松尚衞, 永谷祐子, 川口洋平, 井之上浩一, 浅井清文, 大塚隆信.
- Organizer
  第89回日本整形外科学会学術集会.
- Place of Presentation
  パシフィコ横浜 (神奈川県, 横浜市)
- Year and Date
  2016-05-12
- Data Source
  KAKENHI-PROJECT-26462309
[Presentation] トファシチニブ投与RA患者の臨床像と血清グリオスタチンへの影響の検討.2016
- Author(s)
  川口洋平, 永谷祐子, 立松尚衛, 小林正明, 後藤英之, 野崎正浩, 小栗雄介, 浅井清文, 大塚隆信.
- Organizer
  第60回日本リウマチ学会総会・学術集会
- Place of Presentation
  パシフィコ横浜, 横浜
- Year and Date
  2016-04-22
- Data Source
  KAKENHI-PROJECT-26462309
[Presentation] Sp1 interference prevents joint destruction of RA through inhibitory effects of gliostatin and matrix metalloproteinase-3.2016
- Author(s)
  Ikuta K, Kawaguchi Y, Waguri-Nagaya Y, Tatematsu N, Kobayashi M, Goto H, Nozaki M, Aoyama M, Asai K, Otsuka T.
- Organizer
  Annual European Congress of Rheumatology (EULAR2016)
- Place of Presentation
  ExCel London, London (United Kingdom)
- Year and Date
  2016-06-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462309
[Presentation] 成人脊柱変形の低侵襲化2015
- Author(s)
  水谷　潤、福岡宗良、鈴木伸幸、大塚聖視、大塚隆信
- Organizer
  第88回日本整形外科学会学術総会
- Place of Presentation
  神戸ポートピアホテル他（兵庫県・神戸市）
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-15K10414
[Presentation] The JAK inhibitor (Tofacitinib) inhibits TNF-induced gliostatin/thymidine phosphorylase expression in human fibroblast-like synoviocytes.2015
- Author(s)
  Kawaguchi Y, Waguri-Nagaya Y, Tatematsu N, Kobayashi M, Goto H, Nozaki M, Ikuta K, Aoyama M, Asai K, Otsuka T.
- Organizer
  Annual European Congress of Rheumatology (EULAR2016)
- Place of Presentation
  ExCel London, London, United Kingdom)
- Year and Date
  2015-06-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462309
[Presentation] 関節リウマチ線維芽細胞様滑膜細胞においてTNF-によるグリオスタチン発現はJAK阻害剤により抑制される.2015
- Author(s)
  川口洋平,　永谷祐子, 立松尚衛, 小林正明, 後藤英之，野崎正浩, 青山峰芳, 浅井清文, 大塚隆信.
- Organizer
  第30回日本整形外科基礎学術集会
- Place of Presentation
  富山国際会議場, 富山
- Year and Date
  2015-10-22
- Data Source
  KAKENHI-PROJECT-26462309
[Presentation] The inhibitory effect of synthetic disease-modifying anti-rheumatic drugs and steroids on gliostatin/platelet-derived endothelial cell growth factor production in human fibroblast-like synoviocytes.2015
- Author(s)
  Kawaguchi Y, Waguri-Nagaya Y, Tatematsu N, Kobayashi M, Goto H, Nozaki M, Ikuta K, Aoyama M, Asai K, Otsuka T
- Organizer
  Annual European Congress of Rheumatology (EULAR2015)
- Place of Presentation
  Fiera Roma, Roma, Italy
- Year and Date
  2015-06-10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462309
[Presentation] A Role For P38 Mitogen-Activated Protein Kinase (Mapk) In Gliostatin Production In Rheumatoid Fibroblast-Like Synoviocytes.2015
- Author(s)
  Ikuta K, Kawaguchi Y, Waguri-Nagaya Y, Tatematsu N, Kobayashi M, Goto H, Nozaki M, Aoyama M, Asai K, Otsuka T.
- Organizer
  Annual European Congress of Rheumatology (EULAR2015)
- Place of Presentation
  Fiera Roma, Roma, Italy
- Year and Date
  2015-06-10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462309
[Presentation] Gliostatin regulates vascular endothelial growth-factor production in human fibroblast-like synoviocytes2014
- Author(s)
  Kawaguchi Y, Waguri-Nagaya Y, Tatematsu N, Kobayashi M, Goto H, Nozaki M, Ikuta K, Aoyama M, Asai K, Otsuka T
- Organizer
  Annual European Congress of Rheumatology
- Place of Presentation
  Le Palais des Congres de Paris, France (発表確定)
- Data Source
  KAKENHI-PROJECT-23592225
[Presentation] The importance of gliostatin as an indicator of disease activity in patients with rheumatoid arthritis.2014
- Author(s)
  Ikuta K, Waguri-Nagaya Y, Tatematsu N, Kawaguchi Y, Kobayashi M, Aoyama M, Asai K, Otsuka T.
- Organizer
  Annual European Congress Of Rheumatology
- Place of Presentation
  Le Palais des Congress de Paris (Paris, FRANCE)
- Data Source
  KAKENHI-PROJECT-24592272
[Presentation] The importance of gliostatin as an indicator of disease activity in patients with rheumatoid arthritis.2014
- Author(s)
  Ikuta K, Waguri-Nagaya Y, Tatematsu N, Kawaguchi Y, Kobayashi M, Aoyama M, Asai K, Otsuka T.
- Organizer
  Annual European Congress of Rheumatology
- Place of Presentation
  Le Palais des Congres de Paris (France)
- Data Source
  KAKENHI-PROJECT-23592225
[Presentation] Gliostatin regulates vascular endothelial growth-factor production in human fibroblast-like synoviocytes.2014
- Author(s)
  Kawaguchi Y, Waguri-Nagaya Y, Tatematsu N, Kobayashi M, Goto H, Nozaki M, Ikuta K, Aoyama M, Asai K, Otsuka T.
- Organizer
  Annual European Congress of Rheumatology
- Place of Presentation
  Le Palais des Congres de Paris (France)
- Data Source
  KAKENHI-PROJECT-23592225
[Presentation] Gliostatin regulates vascular endothelial growth-factor production in human fibroblast-like synoviocytes.2014
- Author(s)
  Kawaguchi Y, Waguri-Nagaya Y, Tatematsu N, Kobayashi M, Goto H, Nozaki M, Ikuta K, Aoyama M, Asai K, Otsuka T.
- Organizer
  Annual European Congress Of Rheumatology
- Place of Presentation
  Le Palais des Congress de Paris (Paris, FRANCE)
- Data Source
  KAKENHI-PROJECT-24592272
[Presentation] The importance of gliostatin as an indicator of disease activity in patients with rheumatoid arthritis2014
- Author(s)
  Ikuta K, Waguri-Nagaya Y, Tatematsu N, Kawaguchi Y, Kobayashi M, Aoyama M, Asai K, Otsuka T
- Organizer
  Annual European Congress of Rheumatology
- Place of Presentation
  Le Palais des Congres de Paris, France (発表確定)
- Data Source
  KAKENHI-PROJECT-23592225
[Presentation] Aquaporin expression in the synovial tissues of patients with osteoarthritis and rheumatoid arthritis2013
- Author(s)
  Naoe Tatematsu, Yuko Waguri-Nagaya, Masashizu Nagahara, Kenji Ikuta, Mineyoshi Aoyama, Kiyofumi Asai and Takanobu Otsuka
- Organizer
  EULAR
- Place of Presentation
  Feria de Madrid (Madrid)
- Data Source
  KAKENHI-PROJECT-24592272
[Presentation] 深部脳神経刺激術後のパーキンソン脊柱変形に対する矯正固定術2013
- Author(s)
  水谷潤、福岡宗良、鈴木伸幸、大塚聖視、長谷川伸一、大塚隆信
- Organizer
  第86回日本整形外科学会学術総会
- Place of Presentation
  広島グリーンアリーナ(広島)
- Data Source
  KAKENHI-PROJECT-24592206
[Presentation] The Sp1 transcription factor is essential for the expression of gliostatin/thymidine phosphorylase in rheumatoid fibroblast-like synoviocytes2013
- Author(s)
  Ikuta K, Waguri-Nagaya Y, Terazawa M, Aoyama M, Asai K, Kobayashi M, Otsuka T
- Organizer
  Annual European Congress of Rheumatology
- Place of Presentation
  Feria de Madrid, Spain
- Year and Date
  2013-06-13
- Data Source
  KAKENHI-PROJECT-23592225
[Presentation] The Sp1 transcription factor is essential for the expression of gliostatin/thymidine phosphorylase in rheumatoid fibroblast-like synoviocytes2013
- Author(s)
  Ikuta K, Waguri-Nagaya Y, Terazawa M, Aoyama M, Asai K, Kobayashi M, Otsuka T
- Organizer
  Annual European Congress of Rheumatology
- Place of Presentation
  IFEMA's Convention and Congress Centres (Madrid, SPAIN)
- Data Source
  KAKENHI-PROJECT-24592272
[Presentation] 骨芽細胞においてPho-kinaseはthyroid hormoneによるosteocalcin産生を抑制的に制御する2013
- Author(s)
  近藤章、加藤賢治、黒柳元、山本尚洋、水谷潤、徳田治彦、小澤修、大塚隆信
- Organizer
  第28回日本整形外科学会基礎学術集会
- Place of Presentation
  幕張メッセ国際会議場(千葉)
- Data Source
  KAKENHI-PROJECT-24592273
[Presentation] 転写因子Sp1は関節リウマチ由来線維芽細胞様滑膜細胞におけるグリオスタチン発現を制御する2013
- Author(s)
  生田憲史,永谷祐子,菊池可絵,青山峰芳,浅井清文,小林正明,大塚隆信
- Organizer
  第57回日本リウマチ学会
- Place of Presentation
  京都国際会議場
- Year and Date
  2013-04-18
- Data Source
  KAKENHI-PROJECT-23592225
[Presentation] Aquaporin expression in the synovial tissues of patients with osteoarthritis and rheumatoid arthritis.2013
- Author(s)
  Tatematsu N, Waguri-Nagaya Y, Nagahara M, Ikuta K, Aoyama M, Asai K, Otsuka T.
- Organizer
  Annual European Congress of Rheumatology
- Place of Presentation
  Feria de Madrid (Spain)
- Data Source
  KAKENHI-PROJECT-23592225
[Presentation] Aquaporin expression in the synovial tissues of patients with osteoarthritis and rheumatoid arthritis.2013
- Author(s)
  Tatematsu N, Waguri-Nagaya Y, Nagahara M, Ikuta K, Aoyama M, Asai K, Otsuka T
- Organizer
  Annual European Congress of Rheumatology
- Place of Presentation
  IFEMA's Convention and Congress Centres (Madrid, SPAIN)
- Data Source
  KAKENHI-PROJECT-24592272
[Presentation] 骨芽細胞においてカテキンはinterleulin-1(IL-1)によるIL-6生産を促進的に制御している2013
- Author(s)
  黒柳元、近藤章、水谷潤、西脇理英、徳田治彦、小澤修、大塚隆信
- Organizer
  第28回日本整形外科学会基礎学術集会
- Place of Presentation
  幕張メッセ国際会議場(千葉)
- Data Source
  KAKENHI-PROJECT-24592273
[Presentation] The Sp1 transcription factor is essential for the expression of gliostatin/thymidine phosphorylase in rheumatoid fibroblast-like synoviocytes.2013
- Author(s)
  Ikuta K, Waguri-Nagaya Y, Terazawa M, Aoyama M, Asai K, Kobayashi M, Otsuka T.
- Organizer
  Annual European Congress of Rheumatology
- Place of Presentation
  Feria de Madrid (Spain)
- Data Source
  KAKENHI-PROJECT-23592225
[Presentation] Aquaporin expression in the synovial tissues of patients with osteoarthritis and rheumatoid arthritis2013
- Author(s)
  Tatematsu N, Waguri-Nagaya Y, Nagahara M, Ikuta K, Aoyama M, Asai K, Otsuka T
- Organizer
  Annual European Congress of Rheumatology
- Place of Presentation
  Feria de Madrid, Spain
- Year and Date
  2013-06-13
- Data Source
  KAKENHI-PROJECT-23592225
[Presentation] 骨芽細胞においてSAPK/JNKはinterleukin-1によるinterleukin-6生産を抑制的に制御している2013
- Author(s)
  山本尚洋、加藤賢治、近藤章、黒柳元、水谷潤、徳田治彦、小澤修、大塚隆信
- Organizer
  第28回日本整形外科学会基礎学術集会
- Place of Presentation
  幕張メッセ国際会議場(千葉)
- Data Source
  KAKENHI-PROJECT-24592273
[Presentation] 悪性リンパ腫化学療法後に深部感染が再燃するも人工肘関節を温存し得た関節リウマチ患者の1例.2012
- Author(s)
  生田憲史，永谷祐子, 多和田兼章, 野崎正浩, 渡邊宣之, 後藤英之, 井口普敬,小林正明, 大塚隆信.
- Organizer
  第42回日本人工関節学会
- Place of Presentation
  沖縄コンベンションセンター(宜野湾市)
- Data Source
  KAKENHI-PROJECT-23592225
[Presentation] 関節リウマチサイトカインネットワークにおけるグリオスタチン2012
- Author(s)
  生田憲史,永谷祐子,菊池可絵,青山峰芳,浅井清文,小林正明,大塚隆信
- Organizer
  第27回日本整形外科基礎学術集会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2012-10-26
- Data Source
  KAKENHI-PROJECT-23592225
[Presentation] 関節リウマチと変形性関節症での膝関節軟骨におけるgliostatin/thymidine phosphorylaseの発現分布2012
- Author(s)
  山上貴也, 永谷祐子,生田憲史,青山峰芳,浅井清文, 大塚隆信
- Organizer
  第27回日本整形外科基礎学術集会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2012-10-27
- Data Source
  KAKENHI-PROJECT-23592225
[Presentation] 深部脳刺激治療を行ったパーキンソン脊柱変形に対する矯正固定術2012
- Author(s)
  水谷　潤、福岡宗良、鈴木伸幸、大塚聖視、大塚隆信
- Organizer
  日本側弯症学会
- Place of Presentation
  神戸国際会議場(神戸）
- Data Source
  KAKENHI-PROJECT-24592206
[Presentation] 関節リウマチと変形性関節症での膝関節軟骨におけるgliostatin/thymidine phosphorylaseの発現分布.2012
- Author(s)
  山上貴也, 永谷祐子，生田憲史，青山峰芳，浅井清文,大塚隆信.
- Organizer
  第27回日本整形外科基礎学術集会
- Place of Presentation
  名古屋国際会議場（名古屋）
- Data Source
  KAKENHI-PROJECT-23592225
[Presentation] 関節リウマチサイトカインネットワークにおけるグリオスタチン.2012
- Author(s)
  生田憲史，永谷祐子，菊池可絵, 青山峰芳，浅井清文, 小林正明，大塚隆信.
- Organizer
  第27回日本整形外科基礎学術集会
- Place of Presentation
  名古屋国際会議場（名古屋）
- Data Source
  KAKENHI-PROJECT-23592225
[Presentation] Sp1転写因子が関節リウマチ線維芽細胞様滑膜細胞でのグリオスタチン発現に関連する2011
- Author(s)
  生田憲史，永谷祐子，菊池可絵，小林正明，大塚隆信，青山峰芳，浅井清文.
- Organizer
  第55回日本リウマチ学会
- Place of Presentation
  神戸（兵庫県）
- Data Source
  KAKENHI-PROJECT-23592225
[Presentation] Primary total hip arhtroplasty using metasul anatomical porous replacement (APR) cup:ten to fifteen years results.2011
- Author(s)
  Nobuyuki Watanabe, Hirotaka Iguchi, Masaaki Kobayashi, Isato Sekiya, Yuko Nagaya, Hideyki Goto, Masahiro Nozaki, Hideki Okamoto, Satona Murakami, Takanobu Otsuka.
- Organizer
  the SICOT XXV Triennial World Congress
- Place of Presentation
  Prague, Czech Republic
- Data Source
  KAKENHI-PROJECT-23592225
[Presentation] Limitations of the gap balancing technique in creating rectangular flexion gap in total knee arthroplasy.2011
- Author(s)
  Masahiro Nozaki, Masaaki Kobayashi, Yuko Nagaya, Hideyki Goto, Hideki Okamoto, Nobuyuki Watanabe, Hirotaka Iguchi, Takanobu Otsuka.
- Organizer
  the SICOT XXV Triennial World Congress
- Place of Presentation
  Prague, Czech Republic
- Data Source
  KAKENHI-PROJECT-23592225
[Presentation] Clinical results of new method for benign bone tumors in femora - arthroscopic curettage.2011
- Author(s)
  Masaaki Kobayashi, Isato Sekiya, Yuko Nagaya, Hideyki Goto, Hideki, Masahiro Nozaki, Hirotaka Iguchi, Nobuyuki Watanabe, Hideki Okamoto, Takanobu Otsuka.
- Organizer
  the SICOT XXV Triennial World Congress
- Place of Presentation
  Prague, Czech Republic
- Data Source
  KAKENHI-PROJECT-23592225
[Presentation] p38 MAPKが関節リウマチ線維芽細胞様滑膜細胞におけるグリオスタチン発現に関与する2011
- Author(s)
  生田憲史，永谷祐子，菊池可絵，大塚隆信，青山峰芳，浅井清文
- Organizer
  第26回日本整形外科学会基礎学術集会
- Place of Presentation
  前橋(群馬県）
- Data Source
  KAKENHI-PROJECT-23592225
[Presentation] FK506 inhibited gliostatin production in patients with rheumatoid arthritis and synoviocytes stumulated by TNF-α2011
- Author(s)
  Ikuta K, Nagaya Y, Yamagami T, Kobayashi M, Nozaki M, Goto H, Aoyama M, Asai K, Otsuka T.
- Organizer
  the SICOT XXV Triennial World Congress
- Place of Presentation
  Prague, Czech Republic
- Data Source
  KAKENHI-PROJECT-23592225
[Presentation] Sp1転写因子が関節リウマチ線維芽細胞様滑膜細胞でのグリオスタチン発現に関連する2011
- Author(s)
  生田憲史,永谷祐子,菊池可絵,小林正明,大塚隆信,青山峰芳,浅井清文
- Organizer
  第55回日本リウマチ学会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2011-07-24
- Data Source
  KAKENHI-PROJECT-23592225
[Presentation] p38 MAPKが関節リウマチ線維芽細胞様滑膜細胞におけるグリオスタチン発現に関与する2011
- Author(s)
  生田憲史,永谷祐子,菊池可絵,大塚隆信,青山峰芳,浅井清文
- Organizer
  第26回日本整形外科学会基礎学術集会
- Place of Presentation
  前橋ベイシア文化ホール
- Year and Date
  2011-10-21
- Data Source
  KAKENHI-PROJECT-23592225
[Presentation] 関節水症におけるアクアポリン発現の検討2008
- Author(s)
  長原正静, 永谷祐子, 山上貴也, 青山峰芳, 浅井清文, 多田豊曠, 大塚隆信
- Organizer
  第23回日本整形外科基礎学術集会
- Place of Presentation
  京都
- Year and Date
  2008-10-24
- Data Source
  KAKENHI-PROJECT-19591760
[Presentation] FK506はリウマチ由来線維芽細胞様滑膜細胞においてgliostatin産生を抑制する2008
- Author(s)
  山上貴也,永谷祐子, 長原正静, 青山峰芳, 浅井清文, 大塚隆信
- Organizer
  第23回日本整形外科基礎学術集会
- Place of Presentation
  京都
- Year and Date
  2008-10-24
- Data Source
  KAKENHI-PROJECT-19591760
[Presentation] 関節リウマチ、変形性膝関節症の滑膜組織におけるアクアポリン発現2008
- Author(s)
  長原正静, 永谷祐子, 山上貴也, 青山峰芳, 浅井清文, 多田豊曠, 大塚隆信
- Organizer
  第59回名古屋市立大学医学会総会
- Place of Presentation
  名古屋
- Year and Date
  2008-12-07
- Data Source
  KAKENHI-PROJECT-19591760
[Presentation] 変形性関節症および関節リウマチの滑膜組織におけるアクアポリンの発現2008
- Author(s)
  長原正静, 永谷祐子, 山上貴也, 青山峰芳, 浅井清文, 大塚隆信
- Organizer
  第52回日本リウマチ学会総会
- Place of Presentation
  札幌
- Year and Date
  2008-04-23
- Data Source
  KAKENHI-PROJECT-19591760
[Presentation] The inhibitory effect of disease-modifying anti-rheumatic drugs and steroids on gliostatin/platelet-derived endothelial cell growth factor production in human fibroblast-like synoviocytes2006
- Author(s)
  Takuma, Kusabe, Yuko, Nagava, Tomoyasu, Tanikawa, Masaaki, Kobayashi, Takanobu, Otsuka, Kiyofumi, Asai
- Organizer
  The 12th APLAR Congress
- Place of Presentation
  Kuala Lumpur, Malaysia
- Year and Date
  2006-03-08
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591670
[Presentation] The importance of gliostatin as an indicator of disease activity in patients with rheumatoid arthritis.
- Author(s)
  Ikuta K, Waguri-Nagaya Y, Tatematsu N, Kawaguchi Y, Kobayashi M, Aoyama M, Asai K, Otsuka T.
- Organizer
  Annual European Congress of Rheumatology
- Place of Presentation
  Le Palais des Congres de Paris (Paris, France)
- Year and Date
  2014-06-11 – 2014-06-14
- Data Source
  KAKENHI-PROJECT-24592272
[Presentation] The inhibitory effect of synthetic disease-modifying anti-rheumatic drugs and steroids on gliostatin/platelet-derived endothelial cell growth factor production in human fibroblast-like synoviocytes.
- Author(s)
  Kawaguchi Y, Waguri-Nagaya Y, Tatematsu N, Kobayashi M, Goto H, Nozaki M, Ikuta K, Aoyama M, Asai K, Otsuka T.
- Organizer
  Annual European Congress of Rheumatology
- Place of Presentation
  Fiera Roma (Roma, Italy)
- Year and Date
  2015-06-10 – 2015-06-13
- Data Source
  KAKENHI-PROJECT-24592272
[Presentation] The inhibitory effect of synthetic disease-modifying anti-rheumatic drugs and steroids on gliostatin/platelet-derived endothelial cell growth factor production in human fibroblast-like synoviocytes.
- Author(s)
  Kawaguchi Y, Waguri-Nagaya Y, Tatematsu N, Kobayashi M, Goto H, Nozaki M, Ikuta K, Aoyama M, Asai K, Otsuka T.
- Organizer
  Annual European Congress of Rheumatology
- Place of Presentation
  Fiera Roma (Roma, Italy)
- Year and Date
  2015-06-10 – 2015-06-13
- Data Source
  KAKENHI-PROJECT-26462309
[Presentation] 生物学的製剤導入前後にリウマチ関節手術を考慮した症例の検討.
- Author(s)
  永谷祐子, 小林正明, 後藤英之, 野崎正浩, 井口普敬, 大塚隆信.
- Organizer
  第123回中部日本整形外科災害外科学会
- Place of Presentation
  名古屋国際会議場 (愛知県、名古屋市)
- Year and Date
  2014-10-03 – 2014-10-04
- Data Source
  KAKENHI-PROJECT-26462309
[Presentation] The importance of gliostatin as an indicator of disease activity in patients with rheumatoid arthritis.
- Author(s)
  Ikuta K, Waguri-Nagaya Y, Tatematsu N, Kawaguchi Y, Kobayashi M, Aoyama M, Asai K, Otsuka T.
- Organizer
  Annual European Congress of Rheumatology
- Place of Presentation
  Le Palais des Congres de Paris (Paris, France)
- Year and Date
  2014-06-11 – 2014-06-14
- Data Source
  KAKENHI-PROJECT-26462309
[Presentation] 成人脊柱変形に対する腸骨スクリュー併用矯正固定術
- Author(s)
  福岡宗良、水谷潤、鈴木伸幸、大塚聖視、松本圭久、大塚隆信
- Organizer
  第１２３回中部日本整形外科災害外科学会
- Place of Presentation
  名古屋
- Year and Date
  2014-10-03 – 2014-10-04
- Data Source
  KAKENHI-PROJECT-24592206
[Presentation] A Role For P38 Mitogen-Activated Protein Kinase (Mapk) In Gliostatin Production In Rheumatoid Fibroblast-Like Synoviocytes.
- Author(s)
  Ikuta K, Kawaguchi Y, Waguri-Nagaya Y, Tatematsu N, Kobayashi M, Goto H, Nozaki M, Aoyama M, Asai K, Otsuka T.
- Organizer
  Annual European Congress of Rheumatology
- Place of Presentation
  Fiera Roma (Roma, Italy)
- Year and Date
  2015-06-10 – 2015-06-13
- Data Source
  KAKENHI-PROJECT-26462309
[Presentation] 骨芽細胞においてRho-kinaseはBMP-4によるosteocalcin産生を抑制的に制御している
- Author(s)
  山本尚洋、近藤章、黒柳元、貝沼慎悟、水谷潤、徳田治彦、小澤修、大塚隆信
- Organizer
  第29回日本整形外科学会基礎学術集会
- Place of Presentation
  城山観光ホテル（鹿児島）
- Year and Date
  2014-10-09 – 2014-10-10
- Data Source
  KAKENHI-PROJECT-24592273
[Presentation] A Role For P38 Mitogen-Activated Protein Kinase (Mapk) In Gliostatin Production In Rheumatoid Fibroblast-Like Synoviocytes.
- Author(s)
  Ikuta K, Kawaguchi Y, Waguri-Nagaya Y, Tatematsu N, Kobayashi M, Goto H, Nozaki M, Aoyama M, Asai K, Otsuka T.
- Organizer
  Annual European Congress of Rheumatology
- Place of Presentation
  Fiera Roma (Roma, Italy)
- Year and Date
  2015-06-10 – 2015-06-13
- Data Source
  KAKENHI-PROJECT-24592272
[Presentation] 骨芽細胞においてresveratrolはPGF2αによるosteoprotegerin産生を抑制する
- Author(s)
  貝沼慎悟、黒柳元、近藤章、山本尚洋、水谷潤、徳田治彦、小澤修、大塚隆信
- Organizer
  第29回日本整形外科学会基礎学術集会
- Place of Presentation
  城山観光ホテル（鹿児島）
- Year and Date
  2014-10-09 – 2014-10-10
- Data Source
  KAKENHI-PROJECT-24592273
[Presentation] 液体クロマトグラフィー・タンデム質量分析法による関節リウマチ患者の血清中AcSDKPの検討.
- Author(s)
  立松直衛, 永谷祐子, 川口洋平, 菊池可絵, 青山峰芳, 井之上浩一, 浅井清文, 大塚隆信.
- Organizer
  第29回日本整形外科基礎学術集会
- Place of Presentation
  城山観光ホテル (鹿児島県、鹿児島市)
- Year and Date
  2014-10-09 – 2014-10-10
- Data Source
  KAKENHI-PROJECT-26462309
[Presentation] 成人脊柱変形に対するXLIFの有用性とその工夫
- Author(s)
  水谷潤、福岡宗良、鈴木伸幸、大塚聖視、松本圭久、大塚隆信
- Organizer
  第２３回日本脊椎インストルメンテーション学会
- Place of Presentation
  浜松
- Year and Date
  2014-08-29 – 2014-08-30
- Data Source
  KAKENHI-PROJECT-24592206
[Presentation] Gliostatin regulates vascular endothelial growth-factor production in human fibroblast-like synoviocytes.
- Author(s)
  Kawaguchi Y, Waguri-Nagaya Y, Tatematsu N, Kobayashi M, Goto H, Nozaki M, Ikuta K, Aoyama M, Asai K, Otsuka T.
- Organizer
  Annual European Congress of Rheumatology
- Place of Presentation
  Le Palais des Congres de Paris (Paris, France)
- Year and Date
  2014-06-11 – 2014-06-14
- Data Source
  KAKENHI-PROJECT-24592272
[Presentation] 仙骨プレートを使用した腰仙椎固定術における椎体スクリュー刺入部位の解剖学的検討　－臨床症例におけるCT画像から－
- Author(s)
  大塚聖視、福岡宗良、水谷潤、鈴木伸幸、大塚隆信
- Organizer
  第２９回日本整形外科学会基礎学術集会
- Place of Presentation
  鹿児島
- Year and Date
  2014-10-09 – 2014-10-10
- Data Source
  KAKENHI-PROJECT-24592206
[Presentation] 高度局所後弯を有する頚椎変形矯正手術の治療戦略
- Author(s)
  水谷潤、福岡宗良、鈴木伸幸、大塚聖視、大塚隆信
- Organizer
  第４３回日本脊椎脊髄病学会
- Place of Presentation
  京都
- Year and Date
  2014-04-17 – 2014-04-19
- Data Source
  KAKENHI-PROJECT-24592206
[Presentation] Gliostatin regulates vascular endothelial growth-factor production in human fibroblast-like synoviocytes.
- Author(s)
  Kawaguchi Y, Waguri-Nagaya Y, Tatematsu N, Kobayashi M, Goto H, Nozaki M, Ikuta K, Aoyama M, Asai K, Otsuka T.
- Organizer
  Annual European Congress of Rheumatology
- Place of Presentation
  Le Palais des Congres de Paris (Paris, France)
- Year and Date
  2014-06-11 – 2014-06-14
- Data Source
  KAKENHI-PROJECT-26462309

1. NAGAYA Yuko (90291583)

# of Collaborated Projects: 10 results

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2. ASAI Kiyofumi (70212462)

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60. 青山峰芳

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OTSUKA Takanobu 大塚 隆信

大塚 隆信 オオツカ タカノブ

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The molecular target of heat shock protein in bone metabolismPrincipal Investigator

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Aquaporins expression in fibroblast like synoviocytes from OA and RA patientsPrincipal Investigator

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Aquaporin expression in the synovial tissues of patients with rheumatoid arthritis and osteoarthritisPrincipal Investigator

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OTSUKA Takanobu 大塚隆信

大塚隆信オオツカタカノブ