INOUE Makoto 井上誠

… Alternative Names

井上誠イノウエマコト

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Researcher Number	50191888
Other IDs
External Links
Affiliation (Current)	2022: 愛知学院大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2021: 愛知学院大学, 薬学部, 教授 2005 – 2019: 愛知学院大学, 薬学部, 教授 2010: 愛知学院大学, 歯学部, 教授 2002 – 2003: 名古屋市立大学, 大学院・薬学研究科, 助教授 1997 – 1999: 名古屋市立大学, 薬学部, 助教授 … More 1995: 名古屋市立大学, 薬学部, 助教授 1991 – 1993: 名古屋市立大学, 薬学部, 講師 1989 – 1990: 名古屋市立大学, 薬学部, 助手 Less
Review Section/Research Field	Principal Investigator Biological pharmacy / Natural medicines / Chemical pharmacy / Science and Engineering / General internal medicine (including Psychosomatic medicine) / Chemical pharmacy / Basic Section 47050:Environmental and natural pharmaceutical resources-related Except Principal Investigator Surgical dentistry / Chemical pharmacy / Biological pharmacy / General internal medicine (including Psychosomatic medicine) / Bioorganic chemistry / Natural medicines
Keywords	Principal Investigator 核内受容体 / レチノイドX受容体 / アクテオシド / 過酸化水素 / 漢方方剤 / 生薬 / 生活習慣病 / レチノイン酸受容体 / 天然物 / 抗炎症作用 … More / 天然由来アゴニスト / アルツハイマー病 / 脳内炎症 / ジャガイモ / インターフェロンgamma / タンパク質生産 / 植物体再生 / プロトプラスト / 没食子酸 / アポトーシス / 癌転移 / 癌治療薬 / 男性ホルモン / 植物アンドロゲン / 骨粗鬆症 / 関節リウマチ / SARM / 選択的アンドロゲンレセプター修飾因子 / 動脈硬化症 / PPARs / PPAR / 水酸化不飽和モノ脂肪酸 / アトラクチロジノール / ホーノキオール / レチノイン酸受容体アゴニスト / 天然物化学 / ジテルペン / キサントフィル / 食物アレルギー / 肥満 / 漢方薬繁用生薬 / RARアゴニスト / 制御性T細胞 / 漢方繁用生薬 / ドッカツ / pimaradienoic acid / 天然生理活性物質 / インスリン抵抗性 / 皮膚炎 / フェニルエタノイド配糖体 / マクロファージ / 内皮細胞 / TNF-α / IL-1β / IL-6 / ICAM-1 / シグナル伝達 / Acteoside / Phenylethanoid glycoside / Hydrogen peroxide / Macrophage / Endothelial cell / 肝X受容体 / AD治療薬 / 天然由来RXRアゴニスト / アルツハイマー病マウスモデル / ホオノキオール誘導体 / Liver X受容体 / ABCA1 / 薬学 / 天然活性物質 / レチノイドX受容体アゴニスト / ミクログリア / アルツハイマー病疾患マウスモデル / 天然由来核内受容体アゴニスト … More Except Principal Investigator 口唇裂 / 先天異常 / 口蓋裂 / 予防 / 遺伝子解析 / バンキング / ビスフェノールA / 胸腺 / 乳製品 / モンゴル / 漢方方剤 / 天然物 / Trypanosoma / Gallic acid / T.vivax(IL1392) / FK506 binding protein 12 / Peptidyl-prolyl cis-trans isomerase / Histone H3 / Prunus yedoensis / Trapa japonica / キカラスウリ / カラスリン / 堕胎薬 / アミノ酸配列 / 抗腫瘍活性 / タンパク質多型 / 土壌細菌 / 毛状根培養 / Plant protein / Karasurin / Trichosanthes kirilowii var,japonicum / Abortifacient protein / Antiーtumor protein / Amino and sequence / Isoelectrie focusing / BeWo cell / モンゴル人 / 多剤耐性緑膿菌 / 多剤排出ポンプ / MexXY(-OprA) / 東洋医学 / 核内受容体 / 生薬学 / 天然物化学 / メタボリックシンドローム / 動脈硬化 / レチノイド / RXR / honokiol / LXR / 厚朴 / 小柴胡湯 / 大柴胡湯 / マクロファ-ジ / インタ-ロイキンー1 / サイコサポニン / 溶血 / 貧食能 / グリチルリチン / 複合成分 / 生薬配合 / 大柴胡夜 / サポニン / 薬理作用 / コルチコステロン / Kampo prescription / Shosaikoto / Daisaikoto / Macrophage / Interleukin-1 / Saikosaponin / Hemolytic action / Phagocytosis / T.ivirax(IL1392) / T.bruci gambiense(Wellcome株) / 抗トリパノソーマ活性 / 細胞致死活性 / Fuchsia hybrida / 花粉 / 走化反応 / T.bruci gambiense(Wellcome Strain / Anti-Trypanosoma activity / Cytotoxic activity / 没食子酸 / ヒガンバナアルカロイド / アポトーシス / 選択性 / FK506 binding protein12 / 没食子酸誘導体 / 細胞死 / カルシウム / 活性酸素 / Gallic Acid / Zephyranthes alkaloids / Apoptosis / Selectivity / Brassica campertris var. japonica HARA / 抗酸化活性 / NO産生抑制活性 / 抗炎症活性 / フラボノイド / tetragalloyl glucose / Brassica campestris var. japonica HARA / antioxidative activity / Inhibition of NO production / antiinflamatory activity / Bisphenol A / Cleft Lip / Congenital Abnormality / Prevention / Thymus Gland / 制御性T細胞 / 免疫賦活 / 生薬 / 沈香 / 癌 / インターフェロンガンマ / 自己免疫疾患 / ジンコウ / サイトカイン / Treg / 口唇口蓋裂 / 国際協力 / DNA / 先天異常の予防 / チーズの効果 / 疫学研究 Less

アルツハイマー病発症原因「脳内炎症」の天然レチノイドX受容体アゴニストによる制御Principal Investigator
- Principal Investigator
  
  井上誠
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47050:Environmental and natural pharmaceutical resources-related
- Research Institution
  Aichi Gakuin University
Prevention and Treatment of Alzheimer's Disease by Activation of Retinoid X Receptor Heterodimers.Principal Investigator
- Principal Investigator
  
  INOUE MAKOTO
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Natural medicines
- Research Institution
  Aichi Gakuin University
Application of naturally occurring retinoid X receptor agonists to lifestyle-related diseases and inflammatory diseasesPrincipal Investigator
- Principal Investigator
  
  INOUE Makoto
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Natural medicines
- Research Institution
  Aichi Gakuin University
The search and functional analysis of the natural compound promoting the differentiation of regulatory T cells.
- Principal Investigator
  
  KOTANI Hitoshi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Natural medicines
- Research Institution
  Musashino University
Genomic analysis of genes relating to oral and maxillofacial congenital anomalies - Establishing a center of human genome resource banking
- Principal Investigator
  
  NATSUME Nagato
- Project Period (FY)
  2012 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Surgical dentistry
- Research Institution
  Aichi Gakuin University
Investigation of the reasons why Mongolia has few patients with cleft lip and/or palate: the assessment of a preventive effect of dairy products
- Principal Investigator
  
  NATSUME Nagato
- Project Period (FY)
  2012 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Surgical dentistry
- Research Institution
  Aichi Gakuin University
Search for naturally occurring retinoic acid receptor agonists and thier application to immune and allergic diseasesPrincipal Investigator
- Principal Investigator
  
  INOUE Makoto
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Aichi Gakuin University
Metagenomic approach to identify agents to restore anti-pseudomonas drugs against multidrug resistant Pseudomonas aeruginosa (MDRP): use of MDRP mutants lacking multidrug efflux pumps.
- Principal Investigator
  
  MORITA Yuji
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Aichi Gakuin University
Clarify the meaning of Magnolia obovata in Kampo medicine on nuclear receptor activation.
- Principal Investigator
  
  KOTANI Hitoshi
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General internal medicine (including Psychosomatic medicine)
- Research Institution
  Keio University
  Aichi Gakuin University
Study on preventive effects of intake of a large amount of dairy products by Mongolians on cleft lip/palate incidence
- Principal Investigator
  
  NATSUME Nagato
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Aichi Gakuin University
Study on effects of endocrine disrupter on cleft lip and/or palate.
- Principal Investigator
  
  NIIMI Teruyuki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Aichi Gakuin University
Study concerning analysis of genes causing oral congenital anomalies
- Principal Investigator
  
  NATSUME Nagato
- Project Period (FY)
  2007 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Surgical dentistry
- Research Institution
  Aichi Gakuin University
Creation of novel Kampo medicines to prevent or treat coronary vascular diseases elicited by metabolic syndromePrincipal Investigator
- Principal Investigator
  
  INOUE Makoto
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General internal medicine (including Psychosomatic medicine)
- Research Institution
  Aichi Gakuin University
Research concerning Effects of Endocrine Disrupters on Development of Cleft Lip and/or Palate
- Principal Investigator
  
  NIIMI Teruyuki
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Aichi Gakuin University
天然由来選択的アンドロゲンレセプター修飾因子探索と骨粗鬆症・関節リウマチへの応用Principal Investigator
- Principal Investigator
  
  井上誠
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Aichi Gakuin University
Investigation of Biologically Active Antioxidants from Food Plant Waste to Find New Source of Supplement and Medicine
- Principal Investigator
  
  NAGATSU Akito
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bioorganic chemistry
- Research Institution
  Nagoya City University
Investigation of natural products with selective cytotoxicity against tumor cells
- Principal Investigator
  
  OGIHARA Yukio
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Nagoya City University
Phenylethanoid glycosides as a new macrophage-activating factorPrincipal Investigator
- Principal Investigator
  
  INOUE Makoto
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Nagoya City University
癌細胞選択的細胞致死活性を有する天然化合物に関する研究Principal Investigator
- Principal Investigator
  
  井上誠
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Nagoya City University
動物蛋白質の植物塊根、塊茎での特異的発現に関する研究Principal Investigator
- Principal Investigator
  
  井上誠
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  Nagoya City University
植物タンパクの医薬品への応用開発
- Principal Investigator
  
  OGIHARA Yukio
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Nagoya City University
The chemical attractant against T.virax from pollen grains
- Principal Investigator
  
  OGIHARA Yukio
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Nagoya City University
Significance of Crude Drug Composition and Plural Components in Kampo Prescription.
- Principal Investigator
  
  OGIHARA Yukio
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Nagoya City University

[Book] 科学的証拠に基づいた動脈硬化治療の新規漢方方剤の開発2008
- Author(s)
  井上誠
- Total Pages
  4
- Publisher
  薬事日報社
- Data Source
  KAKENHI-PROJECT-19590704
[Journal Article] Discovery and SAR of Natural-Product-Inspired RXR Agonists with Heterodimer Selectivity to PPARδ‐RXR2020
- Author(s)
  Ken-ichi Nakashima, Eiji Yamaguchi, Chihaya Noritake, Yukari Mitsugi, Mayuki Goto, Takao Hirai, Naohito Abe, Eiji Sakai, Masayoshi Oyama, Akichika Itoh, and Makoto Inoue
- Journal Title
  
  ACS Chemical Biology
  
  Volume: -
- DOI
  10.1021/acschembio.0c00146
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08352
[Journal Article] Anti-inflammatory effects of naturally occurring retinoid X receptor agonists isolated from Sophora tonkinensis Gagnep. via retinoid X receptor/liver X receptor heterodimers.2019
- Author(s)
  Wang W, Nakashima KI, Hirai T, Inoue M.
- Journal Title
  
  J Nat Med
  
  Volume: 73 Pages: 419-430
- DOI
  10.1007/s11418-018-01277-1
- NAID
  40021839101
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08352
[Journal Article] 核内受容体レチノオイドX受容体アゴニストの現在と将来2019
- Author(s)
  井上　誠、中島健一、平居貴生
- Journal Title
  
  愛知学院大学薬学会誌
  
  Volume: 12 Pages: 1-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08352
[Journal Article] Neuroprotective effect of naturally occurring RXR agonists isolated from Sophora tonkinensis Gagnep. on amyloid-β-induced cytotoxicity in PC12 cells.2019
- Author(s)
  Wang W, Nakashima KI, Hirai T, Inoue M.
- Journal Title
  
  J Nat Med
  
  Volume: 73 Pages: 154-162
- DOI
  10.1007/s11418-018-1257-z
- NAID
  40021790129
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08352
[Journal Article] Yuccalides A-C, three new phenolic compounds with spiro-structures from the roots of Yucca gloriosa.2016
- Author(s)
  Ken-ichi Nakashima, Naohito Abe, Masayoshi Oyama, Makoto Inoue.
- Journal Title
  
  Fitoterapia
  
  Volume: 111 Pages: 154-159
- DOI
  10.1016/j.fitote.2016.04.009
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460134
[Journal Article] Retinoic acid receptor agonist activity of naturally occurring diterpenes.2014
- Author(s)
  Hiroki Tanabe, Tomohisa Yasui, Hitoshi Kotani, Akito Nagatsu, Makoto Makishima, Sakae Amagaya, Makoto Inoue
- Journal Title
  
  Bioorg Med Chem.
  
  Volume: 22 Pages: 3204-12
- DOI
  10.1016/j.bmc.2014.03.047
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590025, KAKENHI-PROJECT-25460132
[Journal Article] Rexinoids Isolated from Sophora tonkinensis with a Gene Expression Profile Distinct from the Synthetic Rexinoid Bexarotene2014
- Author(s)
  Inoue M, Tanabe H, Nakashima K, Ishida Y, Kotani H.
- Journal Title
  
  Journal of Natural Products
  
  Volume: 25;77(7) Pages: 1670-1677
- DOI
  10.1021/np5002016
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25460132, KAKENHI-PROJECT-26460134
[Journal Article] Retinoic acid receptor agonist activity of naturally occurring diterpenes2014
- Author(s)
  Tanabe Hiroki, Yasui Tomohiro, Kotani Hiroshi, Nagatsu Akito, Makishima Makoto, Amagaya Sakae, Inoue Makoto
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: vol.22 Pages: 3204-3212
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590025
[Journal Article] Identification of a naturally occurring retinoid X receptor agonist from Brazilian green propolis2014
- Author(s)
  Ken-ichi Nakashima, Tohru Murakami, Hiroki Tanabe, Makoto Inoue
- Journal Title
  
  Biochimica et Biophysica Acta-General Subjects
  
  Volume: 1840 Pages: 3034-3041
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460134
[Journal Article] A Naturally Occurring Rexinoid, Honokiol, Can Serve as a Regulator of Various Retinoid X Receptor Heterodimers2012
- Author(s)
  Kotani H, Tanabe H, Mizukami H, Amagaya S, Inoue M.
- Journal Title
  
  Biol. Pharm. Bull.
  
  Volume: 35 Issue: 1 Pages: 1-9
- DOI
  10.1248/bpb.35.1
- NAID
  130001872330
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790754
[Journal Article] β-Cryptoxanthin suppresses the adipogenesis of 3T3-L1 cells via RAR activation.2011
- Author(s)
  Shirakura Yoshiyuki, Takayanagi Katsuhiko, Mukai Katsuyuki, Tanabe Hiroki, Inoue Makoto.
- Journal Title
  
  J. Nutr. Sci. Vitaminol.
  
  Volume: 57 Pages: 426-431
- NAID
  130002103053
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590025
[Journal Article] β-Cryptocanthin suppresses the adipogenesis of 3T3-L1 cells via RAR activation2011
- Author(s)
  Shirakura Yoshiyuki, Takayanagi Katsuhiko, Mukai Katsuyuki, Tanabe Hiroki, Inoue Makoto
- Journal Title
  
  Journal of Nutritional Science and Vitaminology
  
  Volume: vol.57 Pages: 426-431
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590025
[Journal Article] Peroxisome proliferatoractivated receptor γ ligands isolated from Adlay seed(Coix lacryma-jobi L. var. ma-yuen STAPF.)2009
- Author(s)
  Hiroshi Yokoi, Hajime Mizukami, Akito Nagatsu, Takamasa Ohno, Hiroki Tanabe, Makoto Inoue
- Journal Title
  
  Biol. Pharm. Bull. 32(4)
  
  Pages: 735-740
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590704
[Journal Article] β-Cryptoxan thin a novel RAR ligand, induced ATP-binding cassette transporters in macrophages2007
- Author(s)
  Akira Matsumoto Hajime Mizukami, Satoshi Mizuno, Keizo Umegaki, Jun-ichi Nishikawa, Koichi Shudo, Hiroyuki Kagechika, Makoto Inoue
- Journal Title
  
  Biochem. Pharmacol. 74(2)
  
  Pages: 256-264
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590704
[Patent] レチノイドX受容体アゴニスト剤2014
- Inventor(s)
  井上誠，中島健一，田邊宏樹，池野久美子，中村正
- Industrial Property Rights Holder
  井上誠，中島健一，田邊宏樹，池野久美子，中村正
- Industrial Property Rights Type
  特許
- Filing Date
  2014-10-10
- Acquisition Date
  2016-04-15
- Data Source
  KAKENHI-PROJECT-26460134
[Patent] 抗菌薬耐性阻害剤2013
- Inventor(s)
  森田雄二、中島健一、富田純子、田邊宏樹、井上誠、河村好章
- Industrial Property Rights Holder
  森田雄二、中島健一、富田純子、田邊宏樹、井上誠、河村好章
- Industrial Property Rights Type
  特許
- Filing Date
  2013-08-01
- Data Source
  KAKENHI-PROJECT-23790106
[Patent] 抗菌薬耐性阻害剤2013
- Inventor(s)
  森田雄二、中島健一、富田純子、田邉宏樹、井上誠、河村好章
- Industrial Property Rights Holder
  森田雄二、中島健一、富田純子、田邉宏樹、井上誠、河村好章
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2013-160441
- Filing Date
  2013-08-01
- Data Source
  KAKENHI-PROJECT-23790106
[Patent] レチノイン酸受容体アゴニスト剤2010
- Inventor(s)
  井上誠, 他
- Industrial Property Rights Holder
  井上誠, 他
- Industrial Property Number
  2010-229890
- Filing Date
  2010-10-12
- Data Source
  KAKENHI-PROJECT-20592352
[Patent] レチノイン酸受容体アゴニスト剤2010
- Inventor(s)
  井上誠, 他3名
- Industrial Property Rights Holder
  井上誠, 他3名
- Industrial Property Number
  2010-229890
- Filing Date
  2010-10-12
- Data Source
  KAKENHI-PROJECT-20592352
[Patent] 細胞選択的セレクティブPPARγモジュレーター2008
- Inventor(s)
  井上誠, 大野高政, 田邉宏樹, 高橋二郎, 大木史郎, 山下栄次, 西田光徳
- Industrial Property Rights Holder
  同左
- Filing Date
  2008-03-07
- Data Source
  KAKENHI-PROJECT-19590704
[Patent] 細胞選択的セレクティブPPARモジュレーター2008
- Inventor(s)
  井上誠、大野高政、田邉宏樹、高橋二郎、大木史郎、山下栄次、西田光徳
- Industrial Property Rights Holder
  井上誠、大野高政、田邉宏樹、高橋二郎、大木史郎、山下栄次、西田光徳
- Filing Date
  2008-03-07
- Data Source
  KAKENHI-PROJECT-19590704
[Patent] レチノイン酸受容体アゴニスト剤、レチノイン酸受容体アゴニスト剤を含有する食品、生薬又はその抽出物の使用、レチノイドX受容体アゴニスト剤、レチノイドX受容体アゴニスト剤を含有する食品及びコウボク又はその抽出物の使用2007
- Inventor(s)
  井上誠、小谷仁司、水上元
- Industrial Property Rights Holder
  井上誠
- Filing Date
  2007-07-20
- Data Source
  KAKENHI-PROJECT-19590704
[Patent] レチノイン酸受容体アゴニスト剤、レチノイン酸受容体アゴニスト剤を含有する食品、生薬又はその抽出物の使用、レチノイドX受容体アゴニスト剤、レチノイドX受容体アゴニスト剤を含有する食品及びコウボク又はその抽出物の使用2007
- Inventor(s)
  井上誠、小谷仁司、水上元
- Industrial Property Rights Holder
  井上誠
- Filing Date
  2007-07-20
- Data Source
  KAKENHI-PROJECT-19590704
[Presentation] 新規レチノイドX受容体アゴニストのミクログリアに及ぼす作用2022
- Author(s)
  冨田浩嗣、坪井知恵、中島健一、山口英士、伊藤彰近、井上誠
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-21K06636
[Presentation] アミロイドβが誘導するPC12細胞死に対するサンズコン由来RXRアゴニストの抑制作用2017
- Author(s)
  王蔚、中島健一、平居貴生、井上誠
- Organizer
  日本薬学会第137年会
- Data Source
  KAKENHI-PROJECT-17K08352
[Presentation] 先天性口蓋瘻孔を合併した粘膜下口蓋裂の1例2016
- Author(s)
  新美照幸、大野磨弥、井村英人、佐久間千里、森明弘、早川統子、井上知佐子、夏目長門
- Organizer
  第40回日本口蓋裂学会総会・学術集会
- Place of Presentation
  ナレッジキャピタルコングレコンベンションセンター（大阪府・大阪市）
- Year and Date
  2016-05-26
- Data Source
  KAKENHI-PROJECT-24249092
[Presentation] 分子標的型研究：和漢薬成分の核内受容体を介した生体調節作用2016
- Author(s)
  井上誠
- Organizer
  第33回和漢医薬学会学術大会
- Place of Presentation
  星薬科大学（東京都・品川区）
- Year and Date
  2016-08-27
- Invited
- Data Source
  KAKENHI-PROJECT-26460134
[Presentation] サンズコン由来RXRアゴニストのMetallothionein誘導作用に関する研究2016
- Author(s)
  王蔚，中島健一，井上誠
- Organizer
  日本生薬学会第63回年会
- Place of Presentation
  富山国際会議場（富山県・富山市）
- Year and Date
  2016-09-24
- Data Source
  KAKENHI-PROJECT-26460134
[Presentation] サンズコン由来RXRアゴニストprenylflavanonesの抗炎症作用（２）2016
- Author(s)
  王蔚，中島健一，井上誠
- Organizer
  第62回日本薬学会東海支部総会・大会
- Place of Presentation
  愛知学院大学薬学部（愛知県・名古屋市）
- Year and Date
  2016-07-11
- Data Source
  KAKENHI-PROJECT-26460134
[Presentation] サンズコン由来RXRアゴニストにより誘導される抗炎症作用関連遺伝子の発現解析2015
- Author(s)
  王　蔚、中島健一、田邊宏樹、井上　誠
- Organizer
  日本生薬学会第62回年会
- Place of Presentation
  長良川国際会議場（岐阜市）
- Year and Date
  2015-09-11
- Data Source
  KAKENHI-PROJECT-26460134
[Presentation] Drupanin is naturally occurring retinoid X receptor agonist from Brazilian green propolis2014
- Author(s)
  Ken-ichi Nakashima, Toshiyuki Tanaka, Hiroko Murata, Kouichi Kaburagi, Makoto Inoue
- Organizer
  The American Society of Pharmacognosy 2014 annual meeting
- Place of Presentation
  Mississippi, USA
- Year and Date
  2014-08-04
- Data Source
  KAKENHI-PROJECT-26460134
[Presentation] 生薬由来成分による緑膿菌のマクロライド・リンコマイシン系薬耐性阻害とそのメカニズムについて2014
- Author(s)
  小嶋悠希、森田雄二、中島健一、富田純子、田邉宏樹、井上誠、河村好章
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Year and Date
  2014-03-28
- Data Source
  KAKENHI-PROJECT-23790106
[Presentation] サンズコン由来RXRアゴニストprenylflavanonesの抗炎症作用2014
- Author(s)
  王　蔚、中島健一、田邊宏樹、井上誠
- Organizer
  日本生薬学会第61回年会
- Place of Presentation
  福岡
- Year and Date
  2014-09-14
- Data Source
  KAKENHI-PROJECT-26460134
[Presentation] 多剤耐性緑膿菌の抗菌薬耐性系阻害物質の探索とその解析2014
- Author(s)
  森田雄二、小嶋悠希、中島健一、富田純子、田邉宏樹、井上誠、河村好章
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Year and Date
  2014-03-28
- Data Source
  KAKENHI-PROJECT-23790106
[Presentation] 生薬由来成分による緑膿菌のマクロライド・リンコマイシン系薬耐性阻害とそのメカニズムについて2014
- Author(s)
  小嶋悠希，森田雄二，中島健一，富田純子，田邉宏樹，井上　誠，河村好章
- Organizer
  日本薬学会　第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-23790106
[Presentation] 多剤耐性緑膿菌の抗菌薬耐性系阻害物質の探索とその解析2014
- Author(s)
  森田雄二，小嶋悠希，中島健一，富田純子，田邉宏樹，井上　誠，河村好章
- Organizer
  日本薬学会　第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-23790106
[Presentation] 山豆根由来RXRアゴニスト活性成分の同定と機能解析2012
- Author(s)
  石田幸大中島健一田邉宏樹小谷仁司永津明人井上誠
- Organizer
  日本生薬学会第59回年会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-23790754
[Presentation] 山豆根由来ＲＸＲアゴニスト活性成分の同定と機能解析2012
- Author(s)
  石田幸大，中島健一，田邉宏樹，小谷仁司，永津明人，井上誠
- Organizer
  日本生薬学会第59回年会
- Place of Presentation
  かずさアカデミアパーク(千葉）
- Data Source
  KAKENHI-PROJECT-23790754
[Presentation] β-クリプトキサンチンによる脂肪細胞分化抑制の作用機序解析2011
- Author(s)
  田邊宏樹、小谷仁司、白倉義之、向井克之、井上誠
- Organizer
  日本生薬学会第58回年会
- Place of Presentation
  東京
- Year and Date
  2011-09-24
- Data Source
  KAKENHI-PROJECT-23590025
[Presentation] 漢方方剤繁用生薬由来レチノイン酸受容体アゴニストの探索と有用性の解析2011
- Author(s)
  田邉宏樹、小谷仁司、安井友浩、野口教好、槇島　誠、井上　誠
- Organizer
  第28回和漢医薬学会学術大会
- Place of Presentation
  富山
- Data Source
  KAKENHI-PROJECT-23790754
[Presentation] 生薬からの天然由来PPARδリガンドの探索と機能解析2011
- Author(s)
  小谷仁司，勝川千尋，中村知世，石田幸大，田邉宏樹，井上誠
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会２０１１
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23790754
[Presentation] 黄連含有イソキノリンアルカロイドの脂肪細胞分化抑制作用に関する機序解析2011
- Author(s)
  片桐由里絵，小谷仁司、田邉宏樹、井上　誠
- Organizer
  日本生薬学会第５８回年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23790754
[Presentation] 漢方方剤繁用生薬由来レチノイン酸受容体アゴニストの探索と有用性の解析2011
- Author(s)
  田邊宏樹、小谷仁司、安井友浩、野口教好、槇島誠、井上誠
- Organizer
  第28回和漢医薬学会学術大会
- Place of Presentation
  富山
- Year and Date
  2011-08-27
- Data Source
  KAKENHI-PROJECT-23590025
[Presentation] 漢方方剤繁用生薬由来レチノイン酸受容体アゴニストの探索と有用性の解析2011
- Author(s)
  田邉宏樹、小谷仁司、安井友浩、野口教好、槇島誠、井上誠
- Organizer
  第28回和漢医薬学会学術大会
- Place of Presentation
  富山
- Data Source
  KAKENHI-PROJECT-23590025
[Presentation] 天然由来核内受容体RXRリガンドhonokiolによるヘテロダイマー活性化調節作用の検討2011
- Author(s)
  小谷仁司、田邉宏樹、水上　元、井上　誠
- Organizer
  第57回日本薬学会東海支部総会・大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23790754
[Presentation] 生薬からの天然由来PPARδリガンドの探索と機能解析2011
- Author(s)
  小谷仁司勝川千尋中村知世石田幸大田邉宏樹井上誠
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2011
- Place of Presentation
  名古屋
- Year and Date
  2011-11-23
- Data Source
  KAKENHI-PROJECT-23790754
[Presentation] 黄連含有イソキノリンアルカロイドの脂肪細胞分化抑制作用に関する機序解析2011
- Author(s)
  片桐由里絵小谷仁司田邉宏樹井上誠
- Organizer
  日本生薬学会第58回年会
- Place of Presentation
  東京
- Year and Date
  2011-09-25
- Data Source
  KAKENHI-PROJECT-23790754
[Presentation] 漢方方剤繁用生薬由来レチノイン酸受容体アゴニストの探索と有用性の解析2011
- Author(s)
  田邉宏樹小谷仁司安井友浩野口教好槇島誠井上誠
- Organizer
  第28回和漢医薬学会学術大会
- Place of Presentation
  富山
- Year and Date
  2011-08-27
- Data Source
  KAKENHI-PROJECT-23790754
[Presentation] 天然由来核内受容体RXR リガンドhonokiolによるヘテロダイマー活性化調節作用の検討2011
- Author(s)
  小谷仁司田邉宏樹水上元井上誠
- Organizer
  第57回日本薬学会東海支部総会・大会
- Place of Presentation
  名古屋
- Year and Date
  2011-07-09
- Data Source
  KAKENHI-PROJECT-23790754
[Presentation] 天然由来RXRリガンドによる核内受容体の機能調節作用2008
- Author(s)
  井上誠
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2008-12-12
- Data Source
  KAKENHI-PROJECT-19590704
[Presentation] 漢方方剤成分による核内レセプターを介した慢性疾患の予防治療2008
- Author(s)
  井上誠
- Organizer
  第25回和漢医薬学会学術大会
- Place of Presentation
  大阪
- Year and Date
  2008-08-30
- Data Source
  KAKENHI-PROJECT-19590704
[Presentation] Coptisineの平滑筋細胞選択的増殖抑制活性の機序解析(3)2008
- Author(s)
  井上誠
- Organizer
  日本生薬学会第55回年会
- Place of Presentation
  長崎
- Year and Date
  2008-09-20
- Data Source
  KAKENHI-PROJECT-19590704
[Presentation] ヨクイニンに含まれるPPARγリガンドの探索2008
- Author(s)
  井上誠
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-27
- Data Source
  KAKENHI-PROJECT-19590704
[Presentation] Coptisineの平滑筋細胞選択的増殖抑制活性の機序解析(4)2008
- Author(s)
  井上誠
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2008-12-13
- Data Source
  KAKENHI-PROJECT-19590704
[Presentation] 漢方方剤成分による核内レセプターを介した慢性疾患の予防治療2008
- Author(s)
  井上誠
- Organizer
  第25回和漢医薬学学術大会
- Place of Presentation
  大阪
- Year and Date
  2008-08-30
- Data Source
  KAKENHI-PROJECT-19590704
[Presentation] 天然由来RAR・RXRリガンドによるマクロファージABCA1の発現誘導2007
- Author(s)
  井上誠
- Organizer
  第30回日本分子生物学会・第80会日本生化学会大会合同大会
- Place of Presentation
  横浜
- Year and Date
  2007-12-12
- Data Source
  KAKENHI-PROJECT-19590704
[Presentation] 口唇口蓋裂を伴ったMoebius症候群の1例
- Author(s)
  森明弘,井村英人,古川博雄,井上知佐子,新美照幸,南克浩,加藤大貴,大野磨弥,中原晋一,山内楓子,鈴木聡,夏目長門
- Organizer
  第54回日本先天異常学会学術集会
- Place of Presentation
  神奈川
- Year and Date
  2014-07-26 – 2014-07-27
- Data Source
  KAKENHI-PROJECT-24249092

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# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
73. KOJIMA Keisuke (40275144)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
74. YOSHIMURA Akihiko (90182815)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
75. KATAKAWA Kazuaki (90433606)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
76. SAMEJIMA Hiroshi (50274775)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
77. ARASAKI Akira (00175960)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
78. OTA Toru (10223835)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
79. MITSUYASU Takeshi (00380519)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
80. ONO Maya (70760718)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
81. IKEDA Yayoi (00202903)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
82. SHIMAZAKI Yoshihiro (10291519)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
83. MITANI Akio (50329611)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
84. NOMOTO Shuji (40300967)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
85. TAKEBE Jun (50295995)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
86. FUJITANI Morioki (60190055)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
87. KOJIMA Yuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
88. KUSU Akane

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
89. TAKAGI Michiyo

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
90. OH I

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
91. HIRUMI Hiroyuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
92. MORI Akihiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
93. SAKUMA Chisato

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
94. NAGATA Erika

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
95. 川村好章

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results

INOUE Makoto 井上 誠

井上 誠 イノウエ マコト

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アルツハイマー病発症原因「脳内炎症」の天然レチノイドX受容体アゴニストによる制御Principal Investigator

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Prevention and Treatment of Alzheimer's Disease by Activation of Retinoid X Receptor Heterodimers.Principal Investigator

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Application of naturally occurring retinoid X receptor agonists to lifestyle-related diseases and inflammatory diseasesPrincipal Investigator

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Search for naturally occurring retinoic acid receptor agonists and thier application to immune and allergic diseasesPrincipal Investigator

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Creation of novel Kampo medicines to prevent or treat coronary vascular diseases elicited by metabolic syndromePrincipal Investigator

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INOUE Makoto 井上誠

井上誠イノウエマコト