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UETA Eisaku  植田 栄作

ORCIDConnect your ORCID iD *help
Researcher Number 10203431
External Links
Affiliation (based on the past Project Information) *help 2010: 高知大学, 教育研究部・医療学系, 講師
2008 – 2009: 高知大学, 教育研究部医療学系, 講師
2007: 高知大学, 医学部付属病院, 講師
2003 – 2007: Kochi Medical School, Department of Oral Surgery, Assistant Professor, 医学部附属病院, 講師
2002: 高知医科大学, 医学部附属病院, 講師 … More
2001: 高知医科大学, 医学部, 助教授
2000 – 2001: 高知医科大学, 医学部・附属病院, 講師
1997 – 1999: Kochi Medical School, Department of Oral Surgery, Research Associate, 医学部・附属病院, 助手
1998: 高知医科大学, 医学部・付属病院, 助手
1998: Kochi Medical School, Department of Oral Surgery, Research Associate, 医学部附属病院, 助手
1997: Kochi Medical School, Department of Oral Surgery, Research Associate, 附属病院, 助手
1995 – 1996: 高知医科大学, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
病態科学系歯学(含放射線系歯学) / Functional basic dentistry
Except Principal Investigator
病態科学系歯学(含放射線系歯学) / Pathobiological dentistry/Dental radiology / Surgical dentistry / Surgical dentistry
Keywords
Principal Investigator
Peptide 2 / neutrophils / aspergillosis / candidiasis / cytochrome P450 / β-defensin / α-defensin / antimicrobial peptide / カンジタ症 / チトクロームp450 … More / Peptide2 / 好中球 / アスペルギルス症 / カンジダ症 / チトクロームP450 / β-ディフェンシン / α-ディフェンシン / 抗菌ペプタイド / PARP / caspase-3 / ミトコンドリア膜電位 / アポトーシス / 扁平上皮癌細胞 / Mn-SOD … More
Except Principal Investigator
Mn-SOD / 活性酸素 / p21 / p53 / アポトーシス / reactive oxygen species / cytokine / サイトカイン / apoptosis / squamous cell carcinoma cells / 扁平上皮癌細胞 / 5-FU / 放射線 / 口腔扁平上皮癌 / Manganese-superoxide dismutase / Akt / タイトジャンクション / 浸潤 / reactive oxygen intermediates / CdK / CD59 / peplomycin / NF-KB / ペプロマイシン / 口腔癌 / oral squamous cell carcinoma / Hvooxia-inducible factor-la / Hypoxia-inducible factor-1α / マンガンSOD / 口腔扁平上皮癌細胞 / HIF-1α / Metastasis / Invasion / Laminin-5 γ2 chain / Claudin-1 / Tight junction / MMP-2 / Laminin-5 γ2鎖 / siRNA / 転移 / Laminin-5γ2鎖 / クローディン / chemotherapeutic drugs / radiation / Bcl-2 family protein / PI3-kinase / hypoxia-inducible factor / Bco-2ファミリー蛋白質 / 抗癌剤 / Bcl-2ファミリー蛋白質 / PI3キナーゼ / 低酸素誘導因子 / β-catenin / claudin / occludin / tight junction / invasion / oral cancer / 活性酵素 / β-カテニン / クラウジン / オクルジン / cytotoxic activity / lymphocyte subpopulation / surface antigens / intranodal injection / ミトコンドリア / AIF / チトクロームC / Fas L / Fas / FGF-2 / IFN-γ / IL-2 / T細胞 / 細胞傷害能 / リンパ球亜集団 / 細胞傷害活性 / リンパ球亜群 / 表面抗原 / リンパ節内注入 / macrophage / neutrophil / saliva / lactoferrin peptide / lactoferrin / candidiasis / ディフェンシン / NADPH / マクロファージ / 好中球 / 唾液 / ラクトフェリンペプタイド / ラクトフェリン / カンジダ症 / LAK cells / HィイD22ィエD2OィイD22ィエD2 / LAK細胞 / H_2O_2 / bcl-2 family / differentiation induction / apoptosis induction / cdk / bcl-2ファミリー / 分化誘導 / アポトーシス誘導 / lipopolysaccharide (LPS) / nuclear factor (NF)-_KB / mononulcear leukocytes / beta_1 and beta_2 integrins / keratinocytes / oral lichen planus / 細胞内シグナル伝達 / チロシンリン酸化 / 接着因子 / migration / LPS / 単核球 / β_1およびβ_2インテグリン / ケラチノサイト / 口腔扁平苔癬 / alpha-smooth muscle actin / signal transduction / superoxide / NF-kappaB / pulmonary fibrosis / Azeptin / アセプチン / redox / redok / iNOS / α-平滑筋アクチン / 情報伝達 / スーパーオキサイド / 肺線維症 / アゼプチン / cyclin-dependent kinase / gamma-rays / TGF-beta / 扁平上皮癌 / サイクリン依存キナーゼ / TGF-β / 薬剤耐性 / 放射線感受性 / Hypoxia-inducible factor-1 / VEGF / 一酸化窒素 / 低酸素 / Tfam / POLG / OGG1 / DNA損傷修復 / 相同組み換え / 17-AAG / Rad51 / DNA損傷 Less
  • Research Projects

    (15 results)
  • Research Products

    (24 results)
  • Co-Researchers

    (9 People)
  •  Effects of hypoxia-targeted therapies combined with chemo-radio therapy in oral squamous cell carcinoma cells

    • Principal Investigator
      YAMAMOTO Tetsuya
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pathobiological dentistry/Dental radiology
    • Research Institution
      Kochi University
  •  Development of novel treatment for oral cancer due to analysis of DNA repair system

    • Principal Investigator
      OSAKI Tokio
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Surgical dentistry
    • Research Institution
      Kochi University
  •  Analysis of redox system regulating the expression of HIF-lα in squamous cell carcinomas

    • Principal Investigator
      YAMAMOTO Tetsuya
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Surgical dentistry
    • Research Institution
      Kochi University
  •  The mechanism of escape from hypoxia-induced apoptosis in squamous cell carcinoma cells.

    • Principal Investigator
      YAMAMOTO Tetsuya
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pathobiological dentistry/Dental radiology
    • Research Institution
      Kochi University
  •  Attempt of suppression of oral cancer invasion by overexpression of tight and adherens junction constitution proteins

    • Principal Investigator
      OKU Naohisa
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathobiological dentistry/Dental radiology
    • Research Institution
      Kochi University
  •  Biological investigation of antimicrobial peptides for the regulation of fungal infectionsPrincipal Investigator

    • Principal Investigator
      UETA Eisaku
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      病態科学系歯学(含放射線系歯学)
    • Research Institution
      Kochi Medical School
  •  Basic investigation on moledules which regulate the sensitivity of oral squamous cell carcinoma (cells) to chemo-radio-immunotherapy

    • Principal Investigator
      OSAKI Tokio
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Surgical dentistry
    • Research Institution
      Kochi Medical School
  •  BIOFILM OF ORAL CANDIDA AND BIOLOGICAL INVESTIGATION ON CANDIDA-REGULATING FACTORS IN SALIVA

    • Principal Investigator
      OSAKI Tokio
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      病態科学系歯学(含放射線系歯学)
    • Research Institution
      Kochi Medical school
  •  GROWTH OF METASTATIC CACNER CELLS IN THE LYMPH NODES AND ITS REGULATION BY LYMPHOCYTES

    • Principal Investigator
      YAMAMOTO Tetsuya
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      病態科学系歯学(含放射線系歯学)
    • Research Institution
      高知医科大学
  •  CLINICAL AND BASIC INVESTIGATION ON APOPTOSIS OF HEAD AND NECK CARCINOMAS BY MULTIDISCIPLINARY TREATMENTS

    • Principal Investigator
      OSAKI Tokio
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      病態科学系歯学(含放射線系歯学)
    • Research Institution
      Kochi Medical School
  •  THE ROLE OF REACTIVE OXYGEN INTERMEDIATES AND THEIR SCAVENGERS ON APOPTOSIS INDUCTION OF SQUAMOUS CELL CARClNOMA CELLS

    • Principal Investigator
      YONEDA Kazunori
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      病態科学系歯学(含放射線系歯学)
    • Research Institution
      Kochi Medical School
  •  γ線および抗癌剤に対する扁平上皮癌細胞の感受性に及ぼすMn-SODの影響Principal Investigator

    • Principal Investigator
      植田 栄作
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Functional basic dentistry
    • Research Institution
      高知医科大学
  •  Intracellular Signal Transduction in Oral Keratinocytes and Infiltrated Lymphocytes Obtained from Patients with Oral Lichen Planus-Biochemical Analysis of the Mechanism of Enhanced Cytokine Generation from Keratinocytes and Infiltration of Lymphocytes

    • Principal Investigator
      YAMAMOTO Tetsuya
    • Project Period (FY)
      1996 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      病態科学系歯学(含放射線系歯学)
    • Research Institution
      Kochi Medical School
  •  THE MECHANISM OF DIFFERENTIATION IN SQUAMOUS CELL CARCINOMA CELLS AND INDUCTION OF APOPTOSIS IN HEAD AND NECK CARCINOMAS

    • Principal Investigator
      OSAKI Tokio
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Surgical dentistry
    • Research Institution
      Kochi Medical School
  •  PULMONARY FIBROSIS INDUCED BY ANTICANCER DRUGS-ITS MECHANISM AND PROPHYLAXIS

    • Principal Investigator
      YONEDA Kazunori
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      病態科学系歯学(含放射線系歯学)
    • Research Institution
      Kochi Medical School

All 2009 2008 2007 2006 2003

All Journal Article Presentation

  • [Journal Article] Combined evaluation of dihydropyrimidine dehydrogenase and thymidine phosphorylate mRNA levels in tumor predicts the histopathological effect of 5-fluorouracil-based chemoradiotherapy.2009

    • Author(s)
      Yoshihisa Tateishi, Yukihiro Tatemoto, Seiji Ohno, Keiko Morishita, Eisaku Ueta, Tetsuya Yamamoto
    • Journal Title

      Cancer Letters 274

      Pages: 187-193

    • NAID

      120001661991

    • Data Source
      KAKENHI-PROJECT-19592300
  • [Journal Article] Combined evaluation of dihydropyrimidine dehydrogenase and thymidine phosphorylate mRNA levels in tumor predicts the histopathological effect of 5-fluorouracil-based chemoradiotherapy.2009

    • Author(s)
      Yoshihisa Tateishi, Yukihiro Tatemoto, Seiji Ohno, Keiko Morishita, Eisaku Ueta, Tetsuya Yamamoto
    • Journal Title

      Cancer Letters 274

      Pages: 187-193

    • NAID

      120001661991

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390480
  • [Journal Article] 上顎に生じた悪性顆粒細胞腫の1例2009

    • Author(s)
      植田栄作, 大野清二, 立石善久, 笹部衣里, 山本哲也
    • Journal Title

      日本口腔外科学会雑誌 55巻

      Pages: 189-193

    • NAID

      10027090235

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390480
  • [Journal Article] Enhancement of apoptotic damage of squamous cell carcinoma cells by inhibition of the mitochondrial DNA repairing system.2008

    • Author(s)
      Ueta E, Sasabe E, Yang Z, Osaki T, Yamamoto T
    • Journal Title

      Cancer Sci 99

      Pages: 2230-2237

    • NAID

      10024013145

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390480
  • [Journal Article] Enhancement of apoptotic damage of squamous cell carcinoma cells by inhibition of the mitochondrial DNA repairing system2008

    • Author(s)
      Eisaku Ueta, Eri Sasabe, Zhu Yang, Tokio Osaki, Tetsuya Yamamoto
    • Journal Title

      Cancer Science 99

      Pages: 2230-2237

    • NAID

      10024013145

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592300
  • [Journal Article] Ionizing irradiation induces apoptotic damage of salivary gland acinar cells via NADPHoxidase 1-dependent superoxide generation.2008

    • Author(s)
      Tateishi Y, Sasabe E, Ueta E, Yamamoto T
    • Journal Title

      Biochem Biophys Res Commun 366

      Pages: 301-307

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390480
  • [Journal Article] Enhancement of apoptotic damage of squamous cell carcinoma. cells by inhibition of the mitochondria] DNA repairinlg system.2008

    • Author(s)
      Ueta E, Sasabe F, Yang Z, Osaki T, Yamamoto T
    • Journal Title

      Cancer Sci 99

      Pages: 2230-2237

    • Data Source
      KAKENHI-PROJECT-19592300
  • [Journal Article] Ionizing irradiation induces apoptotic damage of salivary gland acinar cells via NADPH oxidase 1-dependent superoxide generation.2008

    • Author(s)
      Tateishi Y, Sasabe E, Ueta F, Yamamoto T
    • Journal Title

      Biochem Biophys Res Commun 366

      Pages: 301-307

    • Data Source
      KAKENHI-PROJECT-19592300
  • [Journal Article] Ionizing irradiation induces apoptotic damage of salivary gland acinar cells via NADPH oxidase 1-dependent superoxide generation2007

    • Author(s)
      Tateishi Yoshihisa, Sasabe Eri, Ueta Eisaku, Yamamoto Tetsuya
    • Journal Title

      Biochemical and Biophysical Research Communications 306(2)

      Pages: 301-307

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390544
  • [Journal Article] Tight junction protein claudin-1 enhances the invasive activity of oral squamous cell carcinoma cells by promoting cleavage of laminin-5 gamma2 chain via matrix metalloproteinase (MMP)-2 and membrane-type MMP-1.2006

    • Author(s)
      Oku N, Sasabe E, Ueta E, Yamamoto T, Osaki T
    • Journal Title

      Cancer Res 66

      Pages: 5251-5257

    • Data Source
      KAKENHI-PROJECT-18390544
  • [Journal Article] Concomitant chemo-radio-immunotherapy has a lethal therapeutic effect on tongue carcinomas independent of the clinical stage and histological characteristics of the tumor.2006

    • Author(s)
      Yamamoto T, Oku N, Tatemoto Y, Ueta E, Kamatani T, Sasabe E, Osaki T
    • Journal Title

      Oral Oncol 42

      Pages: 873-879

    • Data Source
      KAKENHI-PROJECT-18390544
  • [Journal Article] 唾液分泌低下-その原因と唾液分泌低下に伴う口腔障害2003

    • Author(s)
      植田栄作
    • Journal Title

      日本口腔科学会雑誌 52.5

      Pages: 277-234

    • NAID

      10014354043

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14370604
  • [Journal Article] The cause of hyposalivation and hyposalivation-induced oral impairment2003

    • Author(s)
      Eisaku Ueta
    • Journal Title

      Journal of the Japanese Stomatological Society 52(5)

      Pages: 227-234

    • NAID

      10014354043

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370604
  • [Journal Article] Tyrosine-nitration of caspase 3 and cytochrome c does not suppress apoptosis induction in squamous cell carcinoma cells2003

    • Author(s)
      Eisaku Ueta
    • Journal Title

      International Journal of Cancer 103(6)

      Pages: 717-722

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370676
  • [Journal Article] Tyrosine-nitration of caspase 3 and cytochrome c does not suppress apoptosis induction in squamous cell carcinoma cells2003

    • Author(s)
      Eisaku Ueta
    • Journal Title

      International Journal of Cancer 103・6

      Pages: 717-722

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14370676
  • [Presentation] 口腔扁平上皮癌細胞における相同組み換えによるDNA損傷応答システムに及ぼすHsp90阻害剤17-AAGの影響について2009

    • Author(s)
      植田栄作, 笹部衣里, 立石善久, 山本哲也
    • Organizer
      第27回日本口腔腫瘍学会総会・学術大会
    • Place of Presentation
      宇都宮(栃木県総合文化センター)
    • Year and Date
      2009-01-30
    • Data Source
      KAKENHI-PROJECT-20390480
  • [Presentation] 口腔扁平上皮癌細胞における相同組み換えによるDNA損傷応答システムに及ぼすHsp90阻害剤17-AAGの影響について.2009

    • Author(s)
      植田栄作, 笹部衣里, 立石善久, 山本哲也
    • Organizer
      第27回日本口腔腫瘍学会総会・学術大会
    • Place of Presentation
      宇都宮
    • Data Source
      KAKENHI-PROJECT-19592300
  • [Presentation] 口腔扁平上皮癌細胞における相同組み換えによるDNA損傷応答システムに及ぼすHsp90阻害剤17-AAGの影響について2009

    • Author(s)
      植田栄作, 笹部衣里, 立石善久, 山本哲也
    • Organizer
      第27回日本口腔腫瘍学会総会・学術大会
    • Place of Presentation
      宇都宮(栃木総合文化センター)
    • Year and Date
      2009-01-30
    • Data Source
      KAKENHI-PROJECT-19592300
  • [Presentation] 口腔扁平上皮癌細胞におけるDNA損傷応答システムを標的とした治療法に関する基礎的検討2008

    • Author(s)
      植田栄作, 立石善久, 佐竹秀太, 本田博之, 山本哲也
    • Organizer
      第62回日本口腔科学会学術集会
    • Place of Presentation
      福岡(福岡国際会議場)
    • Year and Date
      2008-04-18
    • Data Source
      KAKENHI-PROJECT-19592300
  • [Presentation] 口腔扁平上皮癌細胞におけるDNA損傷応答システムを標的とした治療法に関する基礎的検討.2008

    • Author(s)
      植田栄作, 立石善久, 佐竹秀太, 本田博之, 山本哲也
    • Organizer
      第62回日本口腔科学会学術集会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-19592300
  • [Presentation] 口腔扁平上皮癌細胞におけるDNA損傷応答システムを標的とした治療法に関する基礎的検討2008

    • Author(s)
      植田栄作, 立石善久, 佐竹秀太, 本田博之, 山本哲也
    • Organizer
      第62回日本口腔科学会学術集会
    • Place of Presentation
      福岡(福岡国際会議場)
    • Year and Date
      2008-04-18
    • Data Source
      KAKENHI-PROJECT-20390480
  • [Presentation] PI-3K/Aktシグナル抑制による口腔扁平上皮癌のγ線による感受性増強機序の解析2007

    • Author(s)
      植田 栄作
    • Organizer
      第61回日本口腔科学会総会
    • Place of Presentation
      神戸
    • Year and Date
      2007-04-20
    • Data Source
      KAKENHI-PROJECT-19592300
  • [Presentation] P1-3K/Aktシグナル抑制による口腔扁平上皮癌細胞のγ線に対する感受性増強機序の解析.2007

    • Author(s)
      植田栄作, 鎌谷宇明, 笹部衣里, 山本哲也
    • Organizer
      第61回NPO法人日本口腔科学会学術集会
    • Place of Presentation
      神戸市
    • Data Source
      KAKENHI-PROJECT-19592300
  • [Presentation] 口腔扁平上皮癌細胞のHypoxia-inducible factor-1α発現に及ぼす細胞内活性酸素の影響2007

    • Author(s)
      笹部 衣里、大野 清二、植田 栄作、山本 哲也
    • Organizer
      第61回NPO法人日本口腔科学会学術集会
    • Place of Presentation
      神戸市
    • Year and Date
      2007-04-19
    • Data Source
      KAKENHI-PROJECT-18390544
  • 1.  YAMAMOTO Tetsuya (00200824)
    # of Collaborated Projects: 14 results
    # of Collaborated Products: 19 results
  • 2.  OSAKI Tokio (70031995)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 2 results
  • 3.  SASABE Eri (40363288)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 14 results
  • 4.  KAMATANI Takaaki (00315003)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 2 results
  • 5.  YONEDA Kazunori (90182849)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 6.  KIMURA Tsuyoshi (10294836)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 7.  TATEISHI Yoshihisa (20372732)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 11 results
  • 8.  OKU Naohisa (20363286)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 9.  SATAKE Hidetaka (10304685)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results

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