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ISHIMOTO HITOSHI  石本 人士

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HITOSHI Ishimoto  石本 人士

ISHIMOTO Hitoshi  石本 人士

石本 人士  イシモト ヒトシ

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Researcher Number 10212937
Other IDs
Affiliation (Current) 2025: 東海大学, 医学部, 教授
Affiliation (based on the past Project Information) *help 2013 – 2024: 東海大学, 医学部, 教授
2008 – 2011: Tokai University, 医学部, 教授
2008: 東海大学, 医学部, 講師
2006 – 2007: Keio University, School of Medicine, Assistant Professor, 医学部, 講師
2005: 慶應義塾大学, 医学部, 助手
1998 – 2000: 慶應義塾大学, 医学部, 助手
1993: 慶應義塾大学, 医学部, 助手
Review Section/Research Field
Principal Investigator
Embryonic/Neonatal medicine / Obstetrics and gynecology / Basic Section 56040:Obstetrics and gynecology-related / Basic Section 52050:Embryonic medicine and pediatrics-related
Except Principal Investigator
Basic Section 56040:Obstetrics and gynecology-related / Obstetrics and gynecology / Basic Section 52050:Embryonic medicine and pediatrics-related / Embryonic/Neonatal medicine / Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields / Basic Section 52030:Psychiatry-related / Obstetrics and gynecology
Keywords
Principal Investigator
胎児 / ミッドカイン / 妊娠維持 / 副腎 / 羊膜 / 妊娠維持機構 / midkine / 胎児副腎 / コルチゾール / 羊水 … More / 絨毛膜 / 胎児肺 / トランスレーショナルリサーチ / プロゲステロン / adrenal / fetus / 栄養膜細胞 / 胎児シグナル / アンギオテンシン変換酵素 / 虚血再灌流傷害 / 腫瘍壊死因子 / 子宮内胎児発育遅延 / 再灌流傷害 / ラット / 子宮内胎児発育不全 … More
Except Principal Investigator
胎盤 / エピジェネティクス / fetal angiography / SPARC / 幹細胞生物学 / 初期胚 / 初期発生 / 明細胞癌 / エクソソーム / プロゲステロン / 合胞体栄養膜細胞 / Matricellular蛋白 / 合胞体化 / 細胞性栄養膜細胞 / 栄養膜細胞 / ミッドカイン / 浸潤性胎盤 / 霊長類 / PD-1 / PD-L1 / 産後うつ病 / 周産期メンタルサポートチーム / 栄養 / うつ病 / 胎児発育不全 / BDNF/TrkBシグナル / 母児間クロストーク / チロシンキナーゼ受容体TrkB / TrkB / 癌 / 明細胞腺癌 / アイソフォーム / 神経栄養因子受容体TrkB / 卵巣明細胞腺癌 / 卵巣癌 / Hlfoo / Epigenetics / Oocyte / Linker histone / ノックアウト / H1foo / 卵子 / リンカーヒストン / power Doppler / Dystrophin / Duchenne muscular dystrophy / preimplantation genetic diagnosis / パワードプラ法 / ジストロフィン遺伝子 / Duchenne型筋ジストロフィー / 着床前遺伝子診断 / TSP2 / TSP1 / prostaglandin / amnion / matricellular protein / 網羅的遺伝子発現解析 / 羊膜間葉細胞 / マトリクス細胞蛋白 / 羊膜上皮細胞 / Syndecan-3 / NCAM / 胎児副腎 / プロテオグリカン / 副腎 / 胎児 Less
  • Research Projects

    (23 results)
  • Research Products

    (68 results)
  • Co-Researchers

    (32 People)
  •  エクソソーム内包プロゲステロンによる胎児・胎児組織の拒絶防止免疫機構

    • Principal Investigator
      大岩 一平
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      Tokai University
  •  卵巣明細胞腺癌患者の免疫系を再構築した担癌ヒト化マウスによる新規抗がん剤の評価

    • Principal Investigator
      百瀬 浩晃
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56040:Obstetrics and gynecology-related
    • Research Institution
      Tokai University
  •  胎児に由来する妊娠維持シグナルの調節機構と機能Principal Investigator

    • Principal Investigator
      石本 人士
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56040:Obstetrics and gynecology-related
    • Research Institution
      Tokai University
  •  ヒト幹細胞とゲノム・エピゲノム編集による初期発生原理の統合的理解

    • Principal Investigator
      福田 篤
    • Project Period (FY)
      2023 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
    • Research Institution
      Tokai University
  •  産後うつ病と栄養に関する観察研究および周産期メンタルサポートチームによる介入研究

    • Principal Investigator
      山本 賢司
    • Project Period (FY)
      2022 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52030:Psychiatry-related
    • Research Institution
      Tokai University
  •  PD-1/PD-L1シグナル調節による霊長類胎盤の浸潤性獲得機序の解明

    • Principal Investigator
      岡宮 稜子
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56040:Obstetrics and gynecology-related
    • Research Institution
      Tokai University
  •  胎盤栄養膜細胞における胎児特異的蛋白ミッドカインの役割

    • Principal Investigator
      飯田 哲士
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56040:Obstetrics and gynecology-related
    • Research Institution
      Tokai University
  •  Matricellular蛋白SPARCによる細胞性栄養膜細胞の分化制御

    • Principal Investigator
      三塚 加奈子
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56040:Obstetrics and gynecology-related
    • Research Institution
      Tokai University
  •  Monitoring mechanism of fetal brain development via placental BDNF/TrkB signals

    • Principal Investigator
      Goto Yumiko
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      Tokai University
  •  Fetal signal-mediated maintenance of intrauterine environmentPrincipal Investigator

    • Principal Investigator
      ISHIMOTO HITOSHI
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      Tokai University
  •  Analysis of the signals induced by the variant isoforms of TrkB expressed on ovarian clear cell adenocarcinoma

    • Principal Investigator
      GOTO Yumiko
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Tokai University
  •  Studies on pregnancy maintenance mediated by fetal and endocrine factorsPrincipal Investigator

    • Principal Investigator
      ISHIMOTO Hitoshi
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Embryonic/Neonatal medicine
    • Research Institution
      Tokai University
  •  Fetoplacental factors involved in feto-maternal communications: who and howPrincipal Investigator

    • Principal Investigator
      ISHIMOTO Hitoshi
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Embryonic/Neonatal medicine
    • Research Institution
      Tokai University
  •  The role of matrix cellular proteins in amniotic membrane

    • Principal Investigator
      MINEGISHI Kazuhiro
    • Project Period (FY)
      2011 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Keio University
  •  Roles for components of the feto-amniotic unit in maintaining pregnancyPrincipal Investigator

    • Principal Investigator
      ISHIMOTO Hitoshi
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Embryonic/Neonatal medicine
    • Research Institution
      Tokai University
  •  Role of neural cell adhesion molecules in structural and functional remodeling of fetal adrenal glands

    • Principal Investigator
      MINEGISHI Kazuhiro
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Embryonic/Neonatal medicine
    • Research Institution
      Keio University
  •  Studies on possible roles of midkine, a heparin -binding growth factor, in the human feto -amniotic unitPrincipal Investigator

    • Principal Investigator
      ISHIMOTO Hitoshi
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Embryonic/Neonatal medicine
    • Research Institution
      Tokai University
      Keio University
  •  細胞層選択的発現蛋白の機能解析によるヒト胎児副腎層形成機構の解明

    • Principal Investigator
      YOSHIMURA Yashimura
    • Project Period (FY)
      2006
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Embryonic/Neonatal medicine
    • Research Institution
      Keio University
  •  The mechanisms of chromatin remodeling in mammalian oocyte maturation and meiosis

    • Principal Investigator
      TANAKA Mamoru
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Keio University
  •  Roles of midkine, a heparin-binding growth factor, in the fetal adrenal glandPrincipal Investigator

    • Principal Investigator
      ISHIMOTO Hitoshi
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Embryonic/Neonatal medicine
    • Research Institution
      KEIO UNIVERSITY
  •  子宮内胎児発育遅延発症における腫瘍壊死因子の役割に関する検討Principal Investigator

    • Principal Investigator
      石本 人士
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Keio University
  •  Preimplantation genetic diagnosis for X-linked genetic diseases and fetal angiographic analysis for fetal aromaties

    • Principal Investigator
      YOSHIMURA Yashimura
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Keio University
  •  再灌流傷害機序による実験的子宮内胎児発育不全モデルの作成Principal Investigator

    • Principal Investigator
      石本 人士
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Keio University

All 2024 2023 2022 2021 2020 2019 2018 2017 2015 2013 2011 2010 2009 2008 2007 2006 2005 Other

All Journal Article Presentation Book

  • [Book] 標準産科婦人科学 第5版2021

    • Author(s)
      石本人士、他57名
    • Total Pages
      697
    • Publisher
      医学書院
    • ISBN
      9784260042659
    • Data Source
      KAKENHI-PROJECT-19K08307
  • [Book] 脳性麻痺と周産期合併症/イベントとの関連2021

    • Author(s)
      石本人士、他46名
    • Total Pages
      256
    • Publisher
      メジカルビュー社
    • ISBN
      9784758321303
    • Data Source
      KAKENHI-PROJECT-19K08307
  • [Journal Article] Liposome-encapsulated progesterone efficiently suppresses B-lineage cell proliferation.2024

    • Author(s)
      Toshiro Seki, Rikio Suzuki, Shino Ohshima, Yoshiyuki Manabe, Shion Onoue, Yuki Hoshino, Atsushi Yasuda, Ryoji Ito, Hiroshi Kawada, Hitoshi Ishimoto, Takashi Shiina, Yoshie Kametani
    • Journal Title

      Biochemistry and Biophysics Reports

      Volume: - Pages: 101710-101710

    • DOI

      10.1016/j.bbrep.2024.101710

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K07828
  • [Journal Article] Coccomyxa subellipsoidea KJ components enhance the expression of metallothioneins and Th17 cytokines during human T cell activation.2024

    • Author(s)
      Toshiro Seki, Shino Ohshima, Satoko Komatsu, Soga Yamada, Hirofumi Kashiwagi, Yumiko Goto, Banri Tsuda, Akiko Kanno, Atsushi Yasuda, Hitoshi Kuno, Noriko M Tsuji, Takashi Shiina, Yoshie Kametani
    • Journal Title

      Microorganisms in press

      Volume: - Issue: 4 Pages: 741-741

    • DOI

      10.3390/microorganisms12040741

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K07828
  • [Journal Article] Construction of the systemic anticancer immune environment in tumour-bearing humanized mouse by using liposome-encapsulated anti-programmed death ligand 1 antibody-conjugated progesterone2023

    • Author(s)
      Kametani Yoshie、Ito Ryoji、Ohshima Shino、Manabe Yoshiyuki、Tsuda Banri、Kashiwagi Hirofumi、Goto Yumiko、Yasuda Atsushi、Maeki Masatoshi、Tokeshi Manabu、Seki Toshiro、Fukase Koichi、Mikami Mikio、Ando Kiyoshi、Ishimoto Hitoshi、Shiina Takashi
    • Journal Title

      Frontiers in Immunology

      Volume: 14 Pages: 1173728-1173728

    • DOI

      10.3389/fimmu.2023.1173728

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K05608, KAKENHI-PROJECT-21K07828, KAKENHI-PLANNED-21H05074, KAKENHI-PROJECT-20H05675, KAKENHI-PROJECT-20H03828
  • [Journal Article] High-progesterone environment preserves T cell competency by evading glucocorticoid effects on immune regulation.2022

    • Author(s)
      Hirofumi Kashiwagi, Yumiko Goto, Hitoshi Ishimoto, Yoshie Kametani, et al.
    • Journal Title

      Frontiers in Immunology

      Volume: 13 Pages: 1-19

    • DOI

      10.3389/fimmu.2022.1000728

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K07828, KAKENHI-PROJECT-20K06477, KAKENHI-PROJECT-21K16823
  • [Journal Article] 胎盤・胎児ステロイド代謝の総論2022

    • Author(s)
      石本 人士
    • Journal Title

      周産期医学

      Volume: 52 Pages: 15-20

    • Data Source
      KAKENHI-PROJECT-19K08307
  • [Journal Article] 陣痛(分娩)発来機序2021

    • Author(s)
      石本 人士
    • Journal Title

      周産期医学

      Volume: 51増刊 Pages: 290-295

    • Data Source
      KAKENHI-PROJECT-19K08307
  • [Journal Article] Tropomyosin-related kinase B (TrkB) full-length isoform is related to advanced-stage clear cell ovarian cancer (CCOC)2021

    • Author(s)
      Yumiko Goto, Yoshie Kametani, Hitoshi Ishimoto, et al.
    • Journal Title

      European Journal of Gynaecological Oncology

      Volume: 42 Issue: 5 Pages: 899-908

    • DOI

      10.31083/j.ejgo4205137

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K07828
  • [Journal Article] Human PZP and common marmoset A2ML1 as pregnancy related proteins2020

    • Author(s)
      Kashiwagi Hirofumi、Ishimoto Hitoshi、Izumi Sun-ichiro、Seki Toshiro、Kinami Rihito、Otomo Asako、Takahashi Kazumi、Kametani Fuyuki、Hirayama Noriaki、Sasaki Erika、Shiina Takashi、Sakabe Kou、Mikami Mikio、Kametani Yoshie
    • Journal Title

      Scientific Reports

      Volume: 10 Issue: 1 Pages: 5088-5088

    • DOI

      10.1038/s41598-020-61714-8

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07832, KAKENHI-PROJECT-19K18709, KAKENHI-PROJECT-17H03571, KAKENHI-PROJECT-17K11298, KAKENHI-PROJECT-20H03828, KAKENHI-PROJECT-16H06277
  • [Journal Article] Atypical presentation of duodenal atresia concomitant with type-A esophageal atresia in fetal life: a case report.2019

    • Author(s)
      Sakamoto N, Mitsuzuka K, Kanno Y, Hayashi M, Goto Y, Ueno S, Ishimoto H.
    • Journal Title

      The Tokai Journal of Experimental and Clinical Medicine

      Volume: 印刷中

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K10110
  • [Journal Article] Atypical Presentation of Duodenal Atresia Concomitant with Type-A Esophageal Atresia in Fetal Life: A Case Report2019

    • Author(s)
      Sakamoto N, Mitsuzuka K, Kanno Y, Hayashi M, Goto Y, Ueno S, Ishimoto H
    • Journal Title

      The Tokai Journal of Experimental and Clinical Medicine

      Volume: 44 Pages: 31-33

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K11298
  • [Journal Article] 周産期相談310 Q020 妊娠中の食事内容でおなかの赤ちゃんがアトピーになるといわれたのですが、本当でしょうか?2019

    • Author(s)
      後藤優美子、石本人士
    • Journal Title

      周産期医学

      Volume: 49 Pages: 45-46

    • Data Source
      KAKENHI-PROJECT-17K11298
  • [Journal Article] A novel gene (FAM20B encoding glycosaminoglycan xylosylkinase) for neonatal short limb dysplasia resembling Desbuquois dysplasia2019

    • Author(s)
      Kuroda Yukiko、Murakami Hiroaki、Enomoto Yumi、Tsurusaki Yoshinori、Takahashi Kazumi、Mitsuzuka Kanako、Ishimoto Hitoshi、Nishimura Gen、Kurosawa Kenji
    • Journal Title

      Clinical Genetics

      Volume: 印刷中 Issue: 6 Pages: 713-717

    • DOI

      10.1111/cge.13530

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K10110, KAKENHI-PROJECT-17K10069, KAKENHI-PROJECT-17K19536
  • [Journal Article] Retrospective Study of Collection Methods in Laparoscopic Myomectomy2019

    • Author(s)
      Nishijima Y, Suzuki T, Sato K, Kashiwagi H, Shinoda M, Izumi S, Ishimoto H
    • Journal Title

      The Tokai Journal of Experimental and Clinical Medicine

      Volume: 44 Pages: 54-58

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K11298
  • [Journal Article] Development and Function of the Human Fetal Adrenal Cortex : a Key Component in the Feto-Placental Unit2011

    • Author(s)
      Ishimoto H, Jaffe RB
    • Journal Title

      Endocrine Reviews

      Volume: 32(3) Pages: 317-355

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591423
  • [Journal Article] Iwata S 2011Laparoscopic cystectomy of ovarian teratoma in anti-NMDAR encephalitis : two case reports2011

    • Author(s)
      Asai S, Ishimoto H, Yabuno A, Asada H, Seki M
    • Journal Title

      J Minim Invasive Gynecol

      Volume: 18(1) Pages: 135-137

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591423
  • [Journal Article] Prenatal diagnosis of retroperitoneal teratoma : a case report and review of literature2009

    • Author(s)
      Asai S, Ishimoto H, KimS H, Higuchi T, Minegishi K, Tanaka M, Hoshino K, Morikawa Y, Yoshimura Y.
    • Journal Title

      Fetal Diagn Ther 25

      Pages: 76-78

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591288
  • [Journal Article] Expression of ovary-specific acidic protein in steroidogenic tissues : a possible role in steroidogenesis2009

    • Author(s)
      Matsumoto T, Minegishi K, Ishimoto H, Tanaka M, Hennebold JD, Teranishi T, Hattori Y, Furuya M, Higuchi T, Asai S, Kim SH, Miyakoshi K, Yoshimura Y
    • Journal Title

      Endocrinology

      Volume: 150(7) Pages: 3353-3359

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591423
  • [Journal Article] Prenatal diagnosis of retroperitoneal teratoma : a case report and review of literature.2009

    • Author(s)
      Satoshi Asai, Hitoshi Ishimoto, et. al.
    • Journal Title

      Fetal Diagnosis and Therapy 25

      Pages: 76-78

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591288
  • [Journal Article] The Periphery of the Human Fetal Adrenal Gland Is a Site of Angiogenesis: Zonal Differential Expression and Regulation of Angiogenic Factors2008

    • Author(s)
      Ishimoto, H.; Minegishi, K., et. al.
    • Journal Title

      J Clin Endocrinol Metab 61(In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390452
  • [Journal Article] The periphery of the human fetal adrenal gland is a site of angiogenesis : zonal differential expression and regulation of angiogenic factors2008

    • Author(s)
      Ishimoto H, Minegishi K, Higuchi T, Furuya M, Asai S, Kim SH, Tanaka M, Yoshimura Y, Jaffe RB.
    • Journal Title

      J Clin Endocrinol Metab 93

      Pages: 2402-2408

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591288
  • [Journal Article] The periphery of the human fetal adrenal gland is a site of angiogenesis : zonal differential expression and regulation of angiogenic factors.2008

    • Author(s)
      Hitoshi Ishimoto, Kazuhiro Minegishi, et. al.
    • Journal Title

      Journal of Clinical Endocrinology and Metabolism 93

      Pages: 2402-2408

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591288
  • [Journal Article] The Outer Zone of the Human Fetal Adrenal Gland Is a Site of Angiogenesis (Abstract)2007

    • Author(s)
      Ishimoto H, Asai S, Higuchi T, Minegishi K, Tanaka M, Yoshimura Y, Jaffe RB
    • Journal Title

      Reproductive Sciences 14(1) Suppl.

    • Data Source
      KAKENHI-PROJECT-18659313
  • [Journal Article] Syndecan-3 Localization Is Limited to the Definitive Zone of the Human Fetal Adrenal Gland : Implications for Adrenal Development (Abstract)2007

    • Author(s)
      Ishimoto H, Asai S, Higuchi T, Minegishi K, Tanaka M, Yoshimura Y, Jaffe RB
    • Journal Title

      Reproductive Sciences 14(1) Suppl.

    • Data Source
      KAKENHI-PROJECT-18659313
  • [Journal Article] Adrenocorticotropin preferentially up-regulates angiopoietin-2 in the human fetal adrenal gland : implications for coordinated adrenal organ growth and angiogenesis.2006

    • Author(s)
      Ishimoto H, Ginzinger DG, Jaffe RB
    • Journal Title

      Journal of Clinical Endocrinology and Metabolism 91(5)

      Pages: 1905-1915

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591150
  • [Journal Article] Differential Zonal Expression and Adrenocorticotropin Regulation of SPARC, a Matricellular Protein, in the Midgestation Human Fetal Adrenal Gland2006

    • Author(s)
      Ishimoto, H., Matsumoto, T., et. al.
    • Journal Title

      J Clin Endocrinol Metab 91

      Pages: 3208-3214

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390452
  • [Journal Article] Differential zonal expression and adrenocorticotropin regulation of SPARC, a matricellular protein, in the midgestation human fetal adrenal gland : implications for adrenal development.2006

    • Author(s)
      Ishimoto H, Ginzinger DG, Matsumoto T, Hattori Y, Furuya M, Minegishi K, Tanaka M, Yoshimura Y, Jaffe RB
    • Journal Title

      Journal of Clinical Endocrinology and Metabolism 91(8)

      Pages: 3208-3214

    • Data Source
      KAKENHI-PROJECT-17591150
  • [Journal Article] Midkine, a Heparin-Binding Growth Factor, Selectively Stimulates Proliferation of Definitive Zone Cells of the Human Fetal Adrenal Gland2006

    • Author(s)
      Ishimoto, H, et. al.
    • Journal Title

      J Clin Endocrinol Metab 91

      Pages: 1905-1915

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390452
  • [Journal Article] Midkine, a heparin-binding growth factor, selectively stimulates proliferation of definitive zone cells of the human fetal adrenal gland.2006

    • Author(s)
      Ishimoto H, Muench MO, Higuchi T, Minegishi K, Tanaka M, Yoshimura Y, Jaffe RB
    • Journal Title

      Journal of Clinical Endocrinology and Metabolism 91(10)

      Pages: 4050-4056

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591150
  • [Journal Article] Midkine, a Heparin-Binding Growth Factor, Selectively Stimulates Proliferation of Definitive Zone Cells of the Human Fetal Adrenal Gland2006

    • Author(s)
      Ishimoto, H., Muench, M., et. al.
    • Journal Title

      J Clin EndocrinoI Metab 91

      Pages: 1905-1915

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390452
  • [Journal Article] Differential zonal expression and adrenocorticotropin regulation of SPARC, a matricellular protein, in the midgestation human fetal adrenal gland : implications for adrenal development.2006

    • Author(s)
      Ishimoto H, Ginzinger DG, Matusmoto T, Hattori Y, Furuya M, Minegishi K, Tanaka M, Yoshimura Y, Jaffe RB
    • Journal Title

      Journal of Clinical Endocrinology and Metabolism 91(8)

      Pages: 3208-3214

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591150
  • [Journal Article] Differential Zonal Expression and Adrenocorticotropin Regulation of SPARC, a Matricellular Protein, in the Midgestation Human Fetal Adrenal Gland: Implications for Adrenal Development2006

    • Author(s)
      Ishimoto, H, et. al.
    • Journal Title

      J Clin Endocrinol Metab 91

      Pages: 3208-3214

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390452
  • [Journal Article] ヘパリン結合性成長因子Midkineのヒト胎児副腎における役割(会議録)2005

    • Author(s)
      石本人士
    • Journal Title

      日本内分泌学会雑誌 81・1

      Pages: 192-192

    • Data Source
      KAKENHI-PROJECT-17591150
  • [Presentation] Effect of SPARC downregulation on BeWo cells fusion2024

    • Author(s)
      Kenji Izumi, Atsuko Togo, Kanako Mitsuzuka, Kenji Sato, Mikio Mikami, Hitoshi Ishimoto
    • Organizer
      The 76th Annual Congress of the Japan Society of Obstetrics and Gynecology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K09649
  • [Presentation] Construction of Anticancer Immune Environment by Liposome-encapsulated Progesterone conjugated with anti-PD-L1 antibody2023

    • Author(s)
      Yoshie Kametani, Ryoji Ito, Shino Ohshima, Yoshiyuki Manabe, Yusuke Ohno, Keita Ito, Banri Tsuda, Hirofuji Kashiwagi, Yumiko Goto, Atsushi Yasuda, Toshiro Seki, Koichi Fukase, Mikio Mikami, Kiyoshi Ando, Hitoshi Ishimoto, Takashi Shiina
    • Organizer
      The 82nd Annual Meeting of the Japanese Cancer Association
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K07828
  • [Presentation] Construction of Anticancer Immune Environment by Liposome-encapsulated Progesterone conjugated with anti-PD-L1 antibody.2023

    • Author(s)
      Yoshie Kametani, Ryoji Ito, Shino Ohshima, Yoshiyuki Manabe, Yusuke Ohno, Soga Yamada, Keita Ito, Takuya Matsumoto, Koichi Fukase, Banri Tsuda, Hirofumi Kashiwagi, Yumiko Goto, Atsushi Yasuda, Masatoshi Maeki, Manabu Tokeshi, Toshiro Seki, Mikio Mikami, Kiyoshi Ando, Hitoshi Ishimoto, Takashi Shiina
    • Organizer
      The 27th Annual Meeting of Japanese Association of Cancer Immunology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K07828
  • [Presentation] 合胞体栄養膜細胞層の形成制御におけるSPARCの役割2022

    • Author(s)
      東郷敦子、三塚加奈子、坂本奈緒子、飯田哲士、佐藤健二、石本人士
    • Organizer
      第46回日本女性栄養・代謝学会学術集会
    • Data Source
      KAKENHI-PROJECT-22K09649
  • [Presentation] ヒト胎児副腎 この未知なる大きな臓器2021

    • Author(s)
      石本 人士
    • Organizer
      第28回日本ステロイドホルモン学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K08307
  • [Presentation] 妊娠中期に発症したSLEの一例2019

    • Author(s)
      後藤優美子、林伊緒、簡野康平、柏木寛史、林優、三塚加奈子、石本人士
    • Organizer
      第55回日本周産期・新生児医学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K11298
  • [Presentation] Silencing of the Human Mitochondria-Localized Glutamic Acid-Rich Protein (MGARP) Gene Induces Apoptosis in a Cell Line Model for Human Fetal Adrenal.2019

    • Author(s)
      Atsuko Togo, Sachiko Hanawa, Kanako Mitsuzuka, Yumiko Goto, Yoshihiro Nishijima, Masaru Hayashi, Kannno Yasuhira, Masaki Miyazawa, Mariko Miyazawa, Hitoshi Ishimoto
    • Organizer
      The 66th Annual Meeting of the Society for Reproductive Investigation
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10110
  • [Presentation] Progesterone effects on pregnant humoral immunity using humanized mice2019

    • Author(s)
      Yusuke Ohno, Tomoka Shimizu, Hirofumi Kashiwagi, Yumiko Goto, Toshiro Seki, Ryoji Ito, Hitoshi Ishimoto, Yoshie Kametani
    • Organizer
      第14回国際生殖免疫学会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K11298
  • [Presentation] PD-1抗体副作用の抑制を目的とした妊娠関連プロテアーゼインヒビターを 模倣する修飾ペプチド化合物の開発2019

    • Author(s)
      亀谷美恵、石本人士、徳田裕、伊藤亮治、真鍋良幸
    • Organizer
      第4回橋渡し研究戦略的推進プログラムシンポジウム
    • Data Source
      KAKENHI-PROJECT-17K11298
  • [Presentation] Silencing of the Human Mitochondria-Localized Glutamic Acid-Rich Protein (MGARP) Gene Induces Apoptosis in a Cell Line Model for Human Fetal Adrenal2019

    • Author(s)
      Atsuko Togo, Sachiko Hanawa, Kanako Mitsuzuka, Yumiko Goto, Yoshihiro Nishijima, Masaru Hayashi, Kannno Yasuhira, Masaki Miyazawa, Mariko Miyazawa, Hitoshi Ishimoto
    • Organizer
      Society for reproductive investigation 66th annual scientific meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K11298
  • [Presentation] Study on the Kinetics of Pregnancy-Related Proteins in Primates.2018

    • Author(s)
      Hirofumi Kashiwagi, Shunichiro Izumi, Kanako Mitsuzuka, Atsuko Togo, Hitoshi Ishimoto, Mikio Mikami
    • Organizer
      第70回日本産科婦人科学会学術講演会
    • Data Source
      KAKENHI-PROJECT-16K10110
  • [Presentation] Does a short cervix predict antepartum massive hemorrhage in patients with placenta previa?2017

    • Author(s)
      A. Togo Y. Kano M. Shida T. Narayama H. Kashiwagi M. Hayashi K. Mitsuzuka H. Ishimoto
    • Organizer
      The 27th World Congress on Ultrasound in Obstetrics and Gynecology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10110
  • [Presentation] Placental expression profile and regulation of midkine, a multifunctional growth/differentiation factor2015

    • Author(s)
      Atsuko Togo, Kanno Hidetoshi, Narita Atsuya, Mitsuzuka Kanako, Asai Satoshi, Nishimura Osamu, Ishimoto Hitoshi, Izumi Shun-ichirou, Mikami Mikio
    • Organizer
      第67回日本産科婦人科学会学術集会
    • Place of Presentation
      パシフィコ横浜(神奈川県、横浜市)
    • Year and Date
      2015-04-09
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25461655
  • [Presentation] Effects of midkine on adrenocortical cells: differential responses in primary cells and a cell line.2013

    • Author(s)
      Ishimoto H, Minegishi K, Nishimura O, Sato S, Mitsuzuka K, Togo A, Jaffe RB
    • Organizer
      95th Annual Meeting of the Endocrine Society
    • Place of Presentation
      San Francisco, USA
    • Data Source
      KAKENHI-PROJECT-25461655
  • [Presentation] Ontogenic Expression of Angiotensin-Converting Enzyme in the Human Fetal Adrenal Gland : Implication in Angiotensin II-Mediated Aldosterone Synthesis2011

    • Author(s)
      道口健翔、石本人士, 他
    • Organizer
      第93回米国内分泌学会(The Endocrine Society)
    • Place of Presentation
      Boston Convention & Exhibition Center
    • Year and Date
      2011-06-04
    • Data Source
      KAKENHI-PROJECT-21591423
  • [Presentation] Ontogenic Expression of Angiotensin-Converting Enzyme in the Human Fetal Adrenal Gland : Implication in Angiotensin II-Mediated Aldosterone Synthesis2011

    • Author(s)
      Doguchi K, Ishimoto H, Matsumoto T, Kondo A, Sato S, Miyazawa M, Minegishi K, Izumi S, Mikami M, Jaffe RB
    • Organizer
      93th Annual Meeting of the Endocrine Society
    • Place of Presentation
      Boston(The Boston Convention & Exhibition Center), USA
    • Year and Date
      2011-06-04
    • Data Source
      KAKENHI-PROJECT-21591423
  • [Presentation] Midkineのヒト胎児副腎皮質における役割:初代培養細胞とモデル細胞株の比較検討2011

    • Author(s)
      道口健翔、石本人士、宮澤昌樹、和泉俊一郎、Jaffe RB
    • Organizer
      第84回日本内分泌学会
    • Place of Presentation
      神戸(神戸国際展示場)
    • Year and Date
      2011-04-22
    • Data Source
      KAKENHI-PROJECT-21591423
  • [Presentation] The Human Fetal Adrenal Gland : A Key Component of the Feto-Maternal Unit2010

    • Author(s)
      Ishimoto H
    • Organizer
      第23回韓国周産期学会(The Korean Perinatal Society)
    • Place of Presentation
      ソウル(Asan Medical Center)、韓国
    • Year and Date
      2010-11-20
    • Data Source
      KAKENHI-PROJECT-21591423
  • [Presentation] Abundant Expression of Ovary. Specific Acidic Protein in the Midgestation Human Fetal Adrenal Gland : Implications for Fetal Adrenal Androgen Biosynthesis2010

    • Author(s)
      Ishimoto H, Minegishi K, Matsumoto T, Kondo A, Doguchi K, Miyazawa M, Tanaka M, Jaffe RB
    • Organizer
      92th Annual Meeting of the Endocrine Society
    • Place of Presentation
      San Diego(The San Diego Convention Center), USA
    • Year and Date
      2010-06-20
    • Data Source
      KAKENHI-PROJECT-21591423
  • [Presentation] Invitation to Fetal Endocrinology : Signals from the Fetus2010

    • Author(s)
      Ishimoto H
    • Organizer
      第23回韓国周産期学会(The Korean Perinatal Society)
    • Place of Presentation
      ソウル(Samsung Medical Center)、韓国
    • Year and Date
      2010-11-19
    • Data Source
      KAKENHI-PROJECT-21591423
  • [Presentation] The Human Fetal Adrenal Gland : A Key Component of the Feto-Maternal Unit2010

    • Author(s)
      石本人士
    • Organizer
      第23回韓国周産期学会(The Korean Perinatal Society)
    • Place of Presentation
      Asan Medical Center
    • Year and Date
      2010-11-20
    • Data Source
      KAKENHI-PROJECT-21591423
  • [Presentation] Abundant Expression of Ovary-Specific Acidic Protein in the Midgestation Human Fetal Adrenal Gland : Implications for Fetal Adrenal Androgen Biosynthesis2010

    • Author(s)
      石本人士, 他
    • Organizer
      第92回米国内分泌学会(The Endocrine Society)
    • Place of Presentation
      San Diego Convention Center
    • Year and Date
      2010-06-20
    • Data Source
      KAKENHI-PROJECT-21591423
  • [Presentation] Invitation to Fetal Endocrinology : Signals from the Fetus2010

    • Author(s)
      石本人士
    • Organizer
      第23回韓国周産期学会(The Korean Perinatal Society)プレカンファレンスミーティング
    • Place of Presentation
      Samsung Medical Center
    • Year and Date
      2010-11-19
    • Data Source
      KAKENHI-PROJECT-21591423
  • [Presentation] Knockdown of Syndecan-3 Expression Attenuates Adrenocortical Cell Proliferation Induced by Fibroblast Growth Factor-2 : Implication for Human Fetal Adrenal Development2010

    • Author(s)
      Kazuhiro MINEGISHI, Hitoshi ISHIMOTO, Seon Hye KIM, Momo UMEZU, Ikuko KADOHIRA, Kei MIYAKOSHI, Mamoru TANAKA, Yasunori YOSHIMURA
    • Organizer
      ENDO(米国内分泌学会)
    • Place of Presentation
      San Diego, USA
    • Data Source
      KAKENHI-PROJECT-20591305
  • [Presentation] ヒト胎児副腎の層形成機構におけるSyndecan-3の関与の可能性2009

    • Author(s)
      峰岸一宏,石本人士,金善恵,浅井哲,田中守,青木大輔,吉村泰典
    • Organizer
      第61回日本産科婦人科学会
    • Place of Presentation
      国立京都国際会館
    • Data Source
      KAKENHI-PROJECT-20591305
  • [Presentation] ヘパリン結合性成長因子Midkine のヒト胎児羊膜系における発現についての検討2008

    • Author(s)
      樋口隆幸, 石本人士, 金善惠, 浅井哲, 峰岸一宏, 田中守, 青木大輔, 吉村泰典
    • Organizer
      第60回日本産科婦人科学会学術講演会
    • Place of Presentation
      横浜(パシフィコ横浜)
    • Year and Date
      2008-04-15
    • Data Source
      KAKENHI-PROJECT-19591288
  • [Presentation] Profile of Midkine, a Heparin-Binding Growth factor, in Human Amniotic Fluid and Amnion2008

    • Author(s)
      Hitoshi Ishimoto, Takayuki Higuchi, et. al.
    • Organizer
      The Society for Gynecologic Investigation, the 55th annual meeting
    • Place of Presentation
      San Diego,USA
    • Year and Date
      2008-03-27
    • Data Source
      KAKENHI-PROJECT-19591288
  • [Presentation] Regulation of Expression of Angiotensin II Receptor Subtypes and ACTH Receptor by ACTH and Angiotensin II in Human Fetal Adrenal Cells2008

    • Author(s)
      Ishimoto H, Minegishi K, Higuchi T, Asai S, Kim SH, Tanaka M, Yoshimura Y, Jaffe RB
    • Organizer
      90th Annual Meeting of the Endocrine Society
    • Place of Presentation
      San Francisco, USA
    • Year and Date
      2008-06-17
    • Data Source
      KAKENHI-PROJECT-19591288
  • [Presentation] ヘパリン結合性成長因子Midkineのヒト胎児羊膜系における発現についての検討2008

    • Author(s)
      樋口隆幸, 石本人士ら.
    • Organizer
      第60回日本産科婦人科学会学術講演会
    • Place of Presentation
      横浜、パシフイコ横浜
    • Year and Date
      2008-04-15
    • Data Source
      KAKENHI-PROJECT-19591288
  • [Presentation] Profile of Midkine, a Heparin-Binding Growth Factor, in Human Amniotic Fluid and Amnion2008

    • Author(s)
      Ishimoto H, Higuchi T, Minegishi K, Asai S, Kim SH, Tanaka M, Jaffe RB, Yoshimura Y.
    • Organizer
      55th Annual Meeting of the Society for Gynecologic Investigation
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2008-03-27
    • Data Source
      KAKENHI-PROJECT-19591288
  • [Presentation] Expression profile of a heparin-binding growth factor, midkine, in human fetal tissues and the placenta2007

    • Author(s)
      Higuchi T, Ishimoto H, Asai S, Minegishi K, Tanaka M, Yoshimura Y, Jaffe RB.
    • Organizer
      89th Annual Meeting of the Endocrine Society
    • Place of Presentation
      Toronto, Canada..
    • Year and Date
      2007-06-04
    • Data Source
      KAKENHI-PROJECT-19591288
  • [Presentation] Down-regulation of ACTH receptor gene expression by an ACTH-inducible heparin-binding growth factor, midkine in human fetal adrenal cells2007

    • Author(s)
      Ishimoto H, Higuchi T, Asai S, Minegishi K, Tanaka M, Yoshimura Y, Jaffe RB
    • Organizer
      89th Annual Meeting of the Endocrine Society
    • Place of Presentation
      Toronto, Canada
    • Year and Date
      2007-06-04
    • Data Source
      KAKENHI-PROJECT-19591288
  • [Presentation] Placental expression profile and regulation of midkine a multifucntional growth/differentiation factor

    • Author(s)
      Togo A, Kanno H, Narita A, Mitsuzuka K, Asai S, Nishimura O, Ishimoto H, Izumi S, Mikami M
    • Organizer
      第67回日本産婦人科学会学術講演会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2015-04-10 – 2015-04-12
    • Data Source
      KAKENHI-PROJECT-25461655
  • [Presentation] Expression of midkine in the human placenta:a possible role for early placental development

    • Author(s)
      Togo A, Goto Y, Mitsuzuka K, Kanno H, Narita A, Asai S, Miyazawa M, Ishimoto H
    • Organizer
      IFPA 2014 Paris(国際胎盤学会)
    • Place of Presentation
      Paris, les Cordeliers
    • Year and Date
      2014-09-09 – 2014-09-12
    • Data Source
      KAKENHI-PROJECT-25461655
  • 1.  亀谷 美恵 (50338787)
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  • 2.  MINEGISHI Kazuhiro (30276331)
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  • 19.  山本 賢司 (10287071)
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  • 22.  西島 義博 (80453710)
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    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  ASAKO Otomo
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 32.  ITO Ryoji
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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