ISHIMOTO HITOSHI 石本人士

… Alternative Names

HITOSHI Ishimoto 石本人士

ISHIMOTO Hitoshi 石本人士

石本人士イシモトヒトシ

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Researcher Number	10212937
Other IDs
Affiliation (Current)	2025: 東海大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2013 – 2024: 東海大学, 医学部, 教授 2008 – 2011: Tokai University, 医学部, 教授 2008: 東海大学, 医学部, 講師 2006 – 2007: Keio University, School of Medicine, Assistant Professor, 医学部, 講師 2005: 慶應義塾大学, 医学部, 助手 1998 – 2000: 慶應義塾大学, 医学部, 助手 1993: 慶應義塾大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Embryonic/Neonatal medicine / Obstetrics and gynecology / Basic Section 56040:Obstetrics and gynecology-related / Basic Section 52050:Embryonic medicine and pediatrics-related Except Principal Investigator Basic Section 56040:Obstetrics and gynecology-related / Obstetrics and gynecology / Basic Section 52050:Embryonic medicine and pediatrics-related / Embryonic/Neonatal medicine / Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields / Basic Section 52030:Psychiatry-related / Obstetrics and gynecology
Keywords	Principal Investigator 胎児 / ミッドカイン / 妊娠維持 / 副腎 / 羊膜 / 妊娠維持機構 / midkine / 胎児副腎 / コルチゾール / 羊水 … More / 絨毛膜 / 胎児肺 / トランスレーショナルリサーチ / プロゲステロン / adrenal / fetus / 栄養膜細胞 / 胎児シグナル / アンギオテンシン変換酵素 / 虚血再灌流傷害 / 腫瘍壊死因子 / 子宮内胎児発育遅延 / 再灌流傷害 / ラット / 子宮内胎児発育不全 … More Except Principal Investigator 胎盤 / エピジェネティクス / fetal angiography / SPARC / 幹細胞生物学 / 初期胚 / 初期発生 / 明細胞癌 / エクソソーム / プロゲステロン / 合胞体栄養膜細胞 / Matricellular蛋白 / 合胞体化 / 細胞性栄養膜細胞 / 栄養膜細胞 / ミッドカイン / 浸潤性胎盤 / 霊長類 / PD-1 / PD-L1 / 産後うつ病 / 周産期メンタルサポートチーム / 栄養 / うつ病 / 胎児発育不全 / BDNF/TrkBシグナル / 母児間クロストーク / チロシンキナーゼ受容体TrkB / TrkB / 癌 / 明細胞腺癌 / アイソフォーム / 神経栄養因子受容体TrkB / 卵巣明細胞腺癌 / 卵巣癌 / Hlfoo / Epigenetics / Oocyte / Linker histone / ノックアウト / H1foo / 卵子 / リンカーヒストン / power Doppler / Dystrophin / Duchenne muscular dystrophy / preimplantation genetic diagnosis / パワードプラ法 / ジストロフィン遺伝子 / Duchenne型筋ジストロフィー / 着床前遺伝子診断 / TSP2 / TSP1 / prostaglandin / amnion / matricellular protein / 網羅的遺伝子発現解析 / 羊膜間葉細胞 / マトリクス細胞蛋白 / 羊膜上皮細胞 / Syndecan-3 / NCAM / 胎児副腎 / プロテオグリカン / 副腎 / 胎児 Less

エクソソーム内包プロゲステロンによる胎児・胎児組織の拒絶防止免疫機構
- Principal Investigator
  
  大岩一平
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Tokai University
卵巣明細胞腺癌患者の免疫系を再構築した担癌ヒト化マウスによる新規抗がん剤の評価
- Principal Investigator
  
  百瀬浩晃
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Tokai University
胎児に由来する妊娠維持シグナルの調節機構と機能Principal Investigator
- Principal Investigator
  
  石本人士
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Tokai University
ヒト幹細胞とゲノム・エピゲノム編集による初期発生原理の統合的理解
- Principal Investigator
  
  福田篤
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  Tokai University
産後うつ病と栄養に関する観察研究および周産期メンタルサポートチームによる介入研究
- Principal Investigator
  
  山本賢司
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  Tokai University
PD-1/PD-L1シグナル調節による霊長類胎盤の浸潤性獲得機序の解明
- Principal Investigator
  
  岡宮稜子
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Tokai University
胎盤栄養膜細胞における胎児特異的蛋白ミッドカインの役割
- Principal Investigator
  
  飯田哲士
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Tokai University
Matricellular蛋白SPARCによる細胞性栄養膜細胞の分化制御
- Principal Investigator
  
  三塚加奈子
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Tokai University
Monitoring mechanism of fetal brain development via placental BDNF/TrkB signals
- Principal Investigator
  
  Goto Yumiko
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Tokai University
Fetal signal-mediated maintenance of intrauterine environmentPrincipal Investigator
- Principal Investigator
  
  ISHIMOTO HITOSHI
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Tokai University
Analysis of the signals induced by the variant isoforms of TrkB expressed on ovarian clear cell adenocarcinoma
- Principal Investigator
  
  GOTO Yumiko
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Tokai University
Studies on pregnancy maintenance mediated by fetal and endocrine factorsPrincipal Investigator
- Principal Investigator
  
  ISHIMOTO Hitoshi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Embryonic/Neonatal medicine
- Research Institution
  Tokai University
Fetoplacental factors involved in feto-maternal communications: who and howPrincipal Investigator
- Principal Investigator
  
  ISHIMOTO Hitoshi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Embryonic/Neonatal medicine
- Research Institution
  Tokai University
The role of matrix cellular proteins in amniotic membrane
- Principal Investigator
  
  MINEGISHI Kazuhiro
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Keio University
Roles for components of the feto-amniotic unit in maintaining pregnancyPrincipal Investigator
- Principal Investigator
  
  ISHIMOTO Hitoshi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Embryonic/Neonatal medicine
- Research Institution
  Tokai University
Role of neural cell adhesion molecules in structural and functional remodeling of fetal adrenal glands
- Principal Investigator
  
  MINEGISHI Kazuhiro
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Embryonic/Neonatal medicine
- Research Institution
  Keio University
Studies on possible roles of midkine, a heparin -binding growth factor, in the human feto -amniotic unitPrincipal Investigator
- Principal Investigator
  
  ISHIMOTO Hitoshi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Embryonic/Neonatal medicine
- Research Institution
  Tokai University
  Keio University
細胞層選択的発現蛋白の機能解析によるヒト胎児副腎層形成機構の解明
- Principal Investigator
  
  YOSHIMURA Yashimura
- Project Period (FY)
  2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Embryonic/Neonatal medicine
- Research Institution
  Keio University
The mechanisms of chromatin remodeling in mammalian oocyte maturation and meiosis
- Principal Investigator
  
  TANAKA Mamoru
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Keio University
Roles of midkine, a heparin-binding growth factor, in the fetal adrenal glandPrincipal Investigator
- Principal Investigator
  
  ISHIMOTO Hitoshi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Embryonic/Neonatal medicine
- Research Institution
  KEIO UNIVERSITY
子宮内胎児発育遅延発症における腫瘍壊死因子の役割に関する検討Principal Investigator
- Principal Investigator
  
  石本人士
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Keio University
Preimplantation genetic diagnosis for X-linked genetic diseases and fetal angiographic analysis for fetal aromaties
- Principal Investigator
  
  YOSHIMURA Yashimura
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Keio University
再灌流傷害機序による実験的子宮内胎児発育不全モデルの作成Principal Investigator
- Principal Investigator
  
  石本人士
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Keio University

[Book] 標準産科婦人科学第5版2021
- Author(s)
  石本人士、他57名
- Total Pages
  697
- Publisher
  医学書院
- ISBN
  9784260042659
- Data Source
  KAKENHI-PROJECT-19K08307
[Book] 脳性麻痺と周産期合併症／イベントとの関連2021
- Author(s)
  石本人士、他46名
- Total Pages
  256
- Publisher
  メジカルビュー社
- ISBN
  9784758321303
- Data Source
  KAKENHI-PROJECT-19K08307
[Journal Article] Liposome-encapsulated progesterone efficiently suppresses B-lineage cell proliferation.2024
- Author(s)
  Toshiro Seki, Rikio Suzuki, Shino Ohshima, Yoshiyuki Manabe, Shion Onoue, Yuki Hoshino, Atsushi Yasuda, Ryoji Ito, Hiroshi Kawada, Hitoshi Ishimoto, Takashi Shiina, Yoshie Kametani
- Journal Title
  
  Biochemistry and Biophysics Reports
  
  Volume: - Pages: 101710-101710
- DOI
  10.1016/j.bbrep.2024.101710
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07828
[Journal Article] Coccomyxa subellipsoidea KJ components enhance the expression of metallothioneins and Th17 cytokines during human T cell activation.2024
- Author(s)
  Toshiro Seki, Shino Ohshima, Satoko Komatsu, Soga Yamada, Hirofumi Kashiwagi, Yumiko Goto, Banri Tsuda, Akiko Kanno, Atsushi Yasuda, Hitoshi Kuno, Noriko M Tsuji, Takashi Shiina, Yoshie Kametani
- Journal Title
  
  Microorganisms in press
  
  Volume: - Issue: 4 Pages: 741-741
- DOI
  10.3390/microorganisms12040741
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07828
[Journal Article] Construction of the systemic anticancer immune environment in tumour-bearing humanized mouse by using liposome-encapsulated anti-programmed death ligand 1 antibody-conjugated progesterone2023
- Author(s)
  Kametani Yoshie、Ito Ryoji、Ohshima Shino、Manabe Yoshiyuki、Tsuda Banri、Kashiwagi Hirofumi、Goto Yumiko、Yasuda Atsushi、Maeki Masatoshi、Tokeshi Manabu、Seki Toshiro、Fukase Koichi、Mikami Mikio、Ando Kiyoshi、Ishimoto Hitoshi、Shiina Takashi
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 14 Pages: 1173728-1173728
- DOI
  10.3389/fimmu.2023.1173728
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K05608, KAKENHI-PROJECT-21K07828, KAKENHI-PLANNED-21H05074, KAKENHI-PROJECT-20H05675, KAKENHI-PROJECT-20H03828
[Journal Article] High-progesterone environment preserves T cell competency by evading glucocorticoid effects on immune regulation.2022
- Author(s)
  Hirofumi Kashiwagi, Yumiko Goto, Hitoshi Ishimoto, Yoshie Kametani, et al.
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 13 Pages: 1-19
- DOI
  10.3389/fimmu.2022.1000728
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07828, KAKENHI-PROJECT-20K06477, KAKENHI-PROJECT-21K16823
[Journal Article] 胎盤・胎児ステロイド代謝の総論2022
- Author(s)
  石本人士
- Journal Title
  
  周産期医学
  
  Volume: 52 Pages: 15-20
- Data Source
  KAKENHI-PROJECT-19K08307
[Journal Article] 陣痛(分娩)発来機序2021
- Author(s)
  石本人士
- Journal Title
  
  周産期医学
  
  Volume: 51増刊 Pages: 290-295
- Data Source
  KAKENHI-PROJECT-19K08307
[Journal Article] Tropomyosin-related kinase B (TrkB) full-length isoform is related to advanced-stage clear cell ovarian cancer (CCOC)2021
- Author(s)
  Yumiko Goto, Yoshie Kametani, Hitoshi Ishimoto, et al.
- Journal Title
  
  European Journal of Gynaecological Oncology
  
  Volume: 42 Issue: 5 Pages: 899-908
- DOI
  10.31083/j.ejgo4205137
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07828
[Journal Article] Human PZP and common marmoset A2ML1 as pregnancy related proteins2020
- Author(s)
  Kashiwagi Hirofumi、Ishimoto Hitoshi、Izumi Sun-ichiro、Seki Toshiro、Kinami Rihito、Otomo Asako、Takahashi Kazumi、Kametani Fuyuki、Hirayama Noriaki、Sasaki Erika、Shiina Takashi、Sakabe Kou、Mikami Mikio、Kametani Yoshie
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 5088-5088
- DOI
  10.1038/s41598-020-61714-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07832, KAKENHI-PROJECT-19K18709, KAKENHI-PROJECT-17H03571, KAKENHI-PROJECT-17K11298, KAKENHI-PROJECT-20H03828, KAKENHI-PROJECT-16H06277
[Journal Article] Atypical presentation of duodenal atresia concomitant with type-A esophageal atresia in fetal life: a case report.2019
- Author(s)
  Sakamoto N, Mitsuzuka K, Kanno Y, Hayashi M, Goto Y, Ueno S, Ishimoto H.
- Journal Title
  
  The Tokai Journal of Experimental and Clinical Medicine
  
  Volume: 印刷中
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10110
[Journal Article] Atypical Presentation of Duodenal Atresia Concomitant with Type-A Esophageal Atresia in Fetal Life: A Case Report2019
- Author(s)
  Sakamoto N, Mitsuzuka K, Kanno Y, Hayashi M, Goto Y, Ueno S, Ishimoto H
- Journal Title
  
  The Tokai Journal of Experimental and Clinical Medicine
  
  Volume: 44 Pages: 31-33
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11298
[Journal Article] 周産期相談310 Q020　妊娠中の食事内容でおなかの赤ちゃんがアトピーになるといわれたのですが、本当でしょうか？2019
- Author(s)
  後藤優美子、石本人士
- Journal Title
  
  周産期医学
  
  Volume: 49 Pages: 45-46
- Data Source
  KAKENHI-PROJECT-17K11298
[Journal Article] A novel gene (FAM20B encoding glycosaminoglycan xylosylkinase) for neonatal short limb dysplasia resembling Desbuquois dysplasia2019
- Author(s)
  Kuroda Yukiko、Murakami Hiroaki、Enomoto Yumi、Tsurusaki Yoshinori、Takahashi Kazumi、Mitsuzuka Kanako、Ishimoto Hitoshi、Nishimura Gen、Kurosawa Kenji
- Journal Title
  
  Clinical Genetics
  
  Volume: 印刷中 Issue: 6 Pages: 713-717
- DOI
  10.1111/cge.13530
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10110, KAKENHI-PROJECT-17K10069, KAKENHI-PROJECT-17K19536
[Journal Article] Retrospective Study of Collection Methods in Laparoscopic Myomectomy2019
- Author(s)
  Nishijima Y, Suzuki T, Sato K, Kashiwagi H, Shinoda M, Izumi S, Ishimoto H
- Journal Title
  
  The Tokai Journal of Experimental and Clinical Medicine
  
  Volume: 44 Pages: 54-58
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11298
[Journal Article] Development and Function of the Human Fetal Adrenal Cortex : a Key Component in the Feto-Placental Unit2011
- Author(s)
  Ishimoto H, Jaffe RB
- Journal Title
  
  Endocrine Reviews
  
  Volume: 32(3) Pages: 317-355
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591423
[Journal Article] Iwata S 2011Laparoscopic cystectomy of ovarian teratoma in anti-NMDAR encephalitis : two case reports2011
- Author(s)
  Asai S, Ishimoto H, Yabuno A, Asada H, Seki M
- Journal Title
  
  J Minim Invasive Gynecol
  
  Volume: 18(1) Pages: 135-137
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591423
[Journal Article] Prenatal diagnosis of retroperitoneal teratoma : a case report and review of literature2009
- Author(s)
  Asai S, Ishimoto H, KimS H, Higuchi T, Minegishi K, Tanaka M, Hoshino K, Morikawa Y, Yoshimura Y.
- Journal Title
  
  Fetal Diagn Ther 25
  
  Pages: 76-78
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591288
[Journal Article] Expression of ovary-specific acidic protein in steroidogenic tissues : a possible role in steroidogenesis2009
- Author(s)
  Matsumoto T, Minegishi K, Ishimoto H, Tanaka M, Hennebold JD, Teranishi T, Hattori Y, Furuya M, Higuchi T, Asai S, Kim SH, Miyakoshi K, Yoshimura Y
- Journal Title
  
  Endocrinology
  
  Volume: 150(7) Pages: 3353-3359
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591423
[Journal Article] Prenatal diagnosis of retroperitoneal teratoma : a case report and review of literature.2009
- Author(s)
  Satoshi Asai, Hitoshi Ishimoto, et. al.
- Journal Title
  
  Fetal Diagnosis and Therapy 25
  
  Pages: 76-78
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591288
[Journal Article] The Periphery of the Human Fetal Adrenal Gland Is a Site of Angiogenesis: Zonal Differential Expression and Regulation of Angiogenic Factors2008
- Author(s)
  Ishimoto, H.; Minegishi, K., et. al.
- Journal Title
  
  J Clin Endocrinol Metab 61(In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390452
[Journal Article] The periphery of the human fetal adrenal gland is a site of angiogenesis : zonal differential expression and regulation of angiogenic factors2008
- Author(s)
  Ishimoto H, Minegishi K, Higuchi T, Furuya M, Asai S, Kim SH, Tanaka M, Yoshimura Y, Jaffe RB.
- Journal Title
  
  J Clin Endocrinol Metab 93
  
  Pages: 2402-2408
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591288
[Journal Article] The periphery of the human fetal adrenal gland is a site of angiogenesis : zonal differential expression and regulation of angiogenic factors.2008
- Author(s)
  Hitoshi Ishimoto, Kazuhiro Minegishi, et. al.
- Journal Title
  
  Journal of Clinical Endocrinology and Metabolism 93
  
  Pages: 2402-2408
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591288
[Journal Article] The Outer Zone of the Human Fetal Adrenal Gland Is a Site of Angiogenesis (Abstract)2007
- Author(s)
  Ishimoto H, Asai S, Higuchi T, Minegishi K, Tanaka M, Yoshimura Y, Jaffe RB
- Journal Title
  
  Reproductive Sciences 14(1) Suppl.
- Data Source
  KAKENHI-PROJECT-18659313
[Journal Article] Syndecan-3 Localization Is Limited to the Definitive Zone of the Human Fetal Adrenal Gland : Implications for Adrenal Development (Abstract)2007
- Author(s)
  Ishimoto H, Asai S, Higuchi T, Minegishi K, Tanaka M, Yoshimura Y, Jaffe RB
- Journal Title
  
  Reproductive Sciences 14(1) Suppl.
- Data Source
  KAKENHI-PROJECT-18659313
[Journal Article] Adrenocorticotropin preferentially up-regulates angiopoietin-2 in the human fetal adrenal gland : implications for coordinated adrenal organ growth and angiogenesis.2006
- Author(s)
  Ishimoto H, Ginzinger DG, Jaffe RB
- Journal Title
  
  Journal of Clinical Endocrinology and Metabolism 91(5)
  
  Pages: 1905-1915
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591150
[Journal Article] Differential Zonal Expression and Adrenocorticotropin Regulation of SPARC, a Matricellular Protein, in the Midgestation Human Fetal Adrenal Gland2006
- Author(s)
  Ishimoto, H., Matsumoto, T., et. al.
- Journal Title
  
  J Clin Endocrinol Metab 91
  
  Pages: 3208-3214
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390452
[Journal Article] Differential zonal expression and adrenocorticotropin regulation of SPARC, a matricellular protein, in the midgestation human fetal adrenal gland : implications for adrenal development.2006
- Author(s)
  Ishimoto H, Ginzinger DG, Matsumoto T, Hattori Y, Furuya M, Minegishi K, Tanaka M, Yoshimura Y, Jaffe RB
- Journal Title
  
  Journal of Clinical Endocrinology and Metabolism 91(8)
  
  Pages: 3208-3214
- Data Source
  KAKENHI-PROJECT-17591150
[Journal Article] Midkine, a Heparin-Binding Growth Factor, Selectively Stimulates Proliferation of Definitive Zone Cells of the Human Fetal Adrenal Gland2006
- Author(s)
  Ishimoto, H, et. al.
- Journal Title
  
  J Clin Endocrinol Metab 91
  
  Pages: 1905-1915
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390452
[Journal Article] Midkine, a heparin-binding growth factor, selectively stimulates proliferation of definitive zone cells of the human fetal adrenal gland.2006
- Author(s)
  Ishimoto H, Muench MO, Higuchi T, Minegishi K, Tanaka M, Yoshimura Y, Jaffe RB
- Journal Title
  
  Journal of Clinical Endocrinology and Metabolism 91(10)
  
  Pages: 4050-4056
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591150
[Journal Article] Midkine, a Heparin-Binding Growth Factor, Selectively Stimulates Proliferation of Definitive Zone Cells of the Human Fetal Adrenal Gland2006
- Author(s)
  Ishimoto, H., Muench, M., et. al.
- Journal Title
  
  J Clin EndocrinoI Metab 91
  
  Pages: 1905-1915
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390452
[Journal Article] Differential zonal expression and adrenocorticotropin regulation of SPARC, a matricellular protein, in the midgestation human fetal adrenal gland : implications for adrenal development.2006
- Author(s)
  Ishimoto H, Ginzinger DG, Matusmoto T, Hattori Y, Furuya M, Minegishi K, Tanaka M, Yoshimura Y, Jaffe RB
- Journal Title
  
  Journal of Clinical Endocrinology and Metabolism 91(8)
  
  Pages: 3208-3214
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591150
[Journal Article] Differential Zonal Expression and Adrenocorticotropin Regulation of SPARC, a Matricellular Protein, in the Midgestation Human Fetal Adrenal Gland: Implications for Adrenal Development2006
- Author(s)
  Ishimoto, H, et. al.
- Journal Title
  
  J Clin Endocrinol Metab 91
  
  Pages: 3208-3214
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390452
[Journal Article] ヘパリン結合性成長因子Midkineのヒト胎児副腎における役割(会議録)2005
- Author(s)
  石本人士
- Journal Title
  
  日本内分泌学会雑誌 81・1
  
  Pages: 192-192
- Data Source
  KAKENHI-PROJECT-17591150
[Presentation] Effect of SPARC downregulation on BeWo cells fusion2024
- Author(s)
  Kenji Izumi, Atsuko Togo, Kanako Mitsuzuka, Kenji Sato, Mikio Mikami, Hitoshi Ishimoto
- Organizer
  The 76th Annual Congress of the Japan Society of Obstetrics and Gynecology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09649
[Presentation] Construction of Anticancer Immune Environment by Liposome-encapsulated Progesterone conjugated with anti-PD-L1 antibody2023
- Author(s)
  Yoshie Kametani, Ryoji Ito, Shino Ohshima, Yoshiyuki Manabe, Yusuke Ohno, Keita Ito, Banri Tsuda, Hirofuji Kashiwagi, Yumiko Goto, Atsushi Yasuda, Toshiro Seki, Koichi Fukase, Mikio Mikami, Kiyoshi Ando, Hitoshi Ishimoto, Takashi Shiina
- Organizer
  The 82nd Annual Meeting of the Japanese Cancer Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07828
[Presentation] Construction of Anticancer Immune Environment by Liposome-encapsulated Progesterone conjugated with anti-PD-L1 antibody.2023
- Author(s)
  Yoshie Kametani, Ryoji Ito, Shino Ohshima, Yoshiyuki Manabe, Yusuke Ohno, Soga Yamada, Keita Ito, Takuya Matsumoto, Koichi Fukase, Banri Tsuda, Hirofumi Kashiwagi, Yumiko Goto, Atsushi Yasuda, Masatoshi Maeki, Manabu Tokeshi, Toshiro Seki, Mikio Mikami, Kiyoshi Ando, Hitoshi Ishimoto, Takashi Shiina
- Organizer
  The 27th Annual Meeting of Japanese Association of Cancer Immunology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07828
[Presentation] 合胞体栄養膜細胞層の形成制御におけるSPARCの役割2022
- Author(s)
  東郷敦子、三塚加奈子、坂本奈緒子、飯田哲士、佐藤健二、石本人士
- Organizer
  第46回日本女性栄養・代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-22K09649
[Presentation] ヒト胎児副腎　この未知なる大きな臓器2021
- Author(s)
  石本人士
- Organizer
  第28回日本ステロイドホルモン学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19K08307
[Presentation] 妊娠中期に発症したSLEの一例2019
- Author(s)
  後藤優美子、林伊緒、簡野康平、柏木寛史、林優、三塚加奈子、石本人士
- Organizer
  第55回日本周産期・新生児医学会学術集会
- Data Source
  KAKENHI-PROJECT-17K11298
[Presentation] Silencing of the Human Mitochondria-Localized Glutamic Acid-Rich Protein (MGARP) Gene Induces Apoptosis in a Cell Line Model for Human Fetal Adrenal.2019
- Author(s)
  Atsuko Togo, Sachiko Hanawa, Kanako Mitsuzuka, Yumiko Goto, Yoshihiro Nishijima, Masaru Hayashi, Kannno Yasuhira, Masaki Miyazawa, Mariko Miyazawa, Hitoshi Ishimoto
- Organizer
  The 66th Annual Meeting of the Society for Reproductive Investigation
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10110
[Presentation] Progesterone effects on pregnant humoral immunity using humanized mice2019
- Author(s)
  Yusuke Ohno, Tomoka Shimizu, Hirofumi Kashiwagi, Yumiko Goto, Toshiro Seki, Ryoji Ito, Hitoshi Ishimoto, Yoshie Kametani
- Organizer
  第14回国際生殖免疫学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11298
[Presentation] PD-1抗体副作用の抑制を目的とした妊娠関連プロテアーゼインヒビターを模倣する修飾ペプチド化合物の開発2019
- Author(s)
  亀谷美恵、石本人士、徳田裕、伊藤亮治、真鍋良幸
- Organizer
  第４回橋渡し研究戦略的推進プログラムシンポジウム
- Data Source
  KAKENHI-PROJECT-17K11298
[Presentation] Silencing of the Human Mitochondria-Localized Glutamic Acid-Rich Protein (MGARP) Gene Induces Apoptosis in a Cell Line Model for Human Fetal Adrenal2019
- Author(s)
  Atsuko Togo, Sachiko Hanawa, Kanako Mitsuzuka, Yumiko Goto, Yoshihiro Nishijima, Masaru Hayashi, Kannno Yasuhira, Masaki Miyazawa, Mariko Miyazawa, Hitoshi Ishimoto
- Organizer
  Society for reproductive investigation 66th annual scientific meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11298
[Presentation] Study on the Kinetics of Pregnancy-Related Proteins in Primates.2018
- Author(s)
  Hirofumi Kashiwagi, Shunichiro Izumi, Kanako Mitsuzuka, Atsuko Togo, Hitoshi Ishimoto, Mikio Mikami
- Organizer
  第70回日本産科婦人科学会学術講演会
- Data Source
  KAKENHI-PROJECT-16K10110
[Presentation] Does a short cervix predict antepartum massive hemorrhage in patients with placenta previa?2017
- Author(s)
  A. Togo Y. Kano M. Shida T. Narayama H. Kashiwagi M. Hayashi K. Mitsuzuka H. Ishimoto
- Organizer
  The 27th World Congress on Ultrasound in Obstetrics and Gynecology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10110
[Presentation] Placental expression profile and regulation of midkine, a multifunctional growth/differentiation factor2015
- Author(s)
  Atsuko Togo, Kanno Hidetoshi, Narita Atsuya, Mitsuzuka Kanako, Asai Satoshi, Nishimura Osamu, Ishimoto Hitoshi, Izumi Shun-ichirou, Mikami Mikio
- Organizer
  第67回日本産科婦人科学会学術集会
- Place of Presentation
  パシフィコ横浜（神奈川県、横浜市）
- Year and Date
  2015-04-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461655
[Presentation] Effects of midkine on adrenocortical cells: differential responses in primary cells and a cell line.2013
- Author(s)
  Ishimoto H, Minegishi K, Nishimura O, Sato S, Mitsuzuka K, Togo A, Jaffe RB
- Organizer
  95th Annual Meeting of the Endocrine Society
- Place of Presentation
  San Francisco, USA
- Data Source
  KAKENHI-PROJECT-25461655
[Presentation] Ontogenic Expression of Angiotensin-Converting Enzyme in the Human Fetal Adrenal Gland : Implication in Angiotensin II-Mediated Aldosterone Synthesis2011
- Author(s)
  道口健翔、石本人士, 他
- Organizer
  第93回米国内分泌学会(The Endocrine Society)
- Place of Presentation
  Boston Convention & Exhibition Center
- Year and Date
  2011-06-04
- Data Source
  KAKENHI-PROJECT-21591423
[Presentation] Ontogenic Expression of Angiotensin-Converting Enzyme in the Human Fetal Adrenal Gland : Implication in Angiotensin II-Mediated Aldosterone Synthesis2011
- Author(s)
  Doguchi K, Ishimoto H, Matsumoto T, Kondo A, Sato S, Miyazawa M, Minegishi K, Izumi S, Mikami M, Jaffe RB
- Organizer
  93th Annual Meeting of the Endocrine Society
- Place of Presentation
  Boston(The Boston Convention & Exhibition Center), USA
- Year and Date
  2011-06-04
- Data Source
  KAKENHI-PROJECT-21591423
[Presentation] Midkineのヒト胎児副腎皮質における役割:初代培養細胞とモデル細胞株の比較検討2011
- Author(s)
  道口健翔、石本人士、宮澤昌樹、和泉俊一郎、Jaffe RB
- Organizer
  第84回日本内分泌学会
- Place of Presentation
  神戸(神戸国際展示場)
- Year and Date
  2011-04-22
- Data Source
  KAKENHI-PROJECT-21591423
[Presentation] The Human Fetal Adrenal Gland : A Key Component of the Feto-Maternal Unit2010
- Author(s)
  Ishimoto H
- Organizer
  第23回韓国周産期学会(The Korean Perinatal Society)
- Place of Presentation
  ソウル(Asan Medical Center)、韓国
- Year and Date
  2010-11-20
- Data Source
  KAKENHI-PROJECT-21591423
[Presentation] Abundant Expression of Ovary. Specific Acidic Protein in the Midgestation Human Fetal Adrenal Gland : Implications for Fetal Adrenal Androgen Biosynthesis2010
- Author(s)
  Ishimoto H, Minegishi K, Matsumoto T, Kondo A, Doguchi K, Miyazawa M, Tanaka M, Jaffe RB
- Organizer
  92th Annual Meeting of the Endocrine Society
- Place of Presentation
  San Diego(The San Diego Convention Center), USA
- Year and Date
  2010-06-20
- Data Source
  KAKENHI-PROJECT-21591423
[Presentation] Invitation to Fetal Endocrinology : Signals from the Fetus2010
- Author(s)
  Ishimoto H
- Organizer
  第23回韓国周産期学会(The Korean Perinatal Society)
- Place of Presentation
  ソウル(Samsung Medical Center)、韓国
- Year and Date
  2010-11-19
- Data Source
  KAKENHI-PROJECT-21591423
[Presentation] The Human Fetal Adrenal Gland : A Key Component of the Feto-Maternal Unit2010
- Author(s)
  石本人士
- Organizer
  第23回韓国周産期学会(The Korean Perinatal Society)
- Place of Presentation
  Asan Medical Center
- Year and Date
  2010-11-20
- Data Source
  KAKENHI-PROJECT-21591423
[Presentation] Abundant Expression of Ovary-Specific Acidic Protein in the Midgestation Human Fetal Adrenal Gland : Implications for Fetal Adrenal Androgen Biosynthesis2010
- Author(s)
  石本人士, 他
- Organizer
  第92回米国内分泌学会(The Endocrine Society)
- Place of Presentation
  San Diego Convention Center
- Year and Date
  2010-06-20
- Data Source
  KAKENHI-PROJECT-21591423
[Presentation] Invitation to Fetal Endocrinology : Signals from the Fetus2010
- Author(s)
  石本人士
- Organizer
  第23回韓国周産期学会(The Korean Perinatal Society)プレカンファレンスミーティング
- Place of Presentation
  Samsung Medical Center
- Year and Date
  2010-11-19
- Data Source
  KAKENHI-PROJECT-21591423
[Presentation] Knockdown of Syndecan-3 Expression Attenuates Adrenocortical Cell Proliferation Induced by Fibroblast Growth Factor-2 : Implication for Human Fetal Adrenal Development2010
- Author(s)
  Kazuhiro MINEGISHI, Hitoshi ISHIMOTO, Seon Hye KIM, Momo UMEZU, Ikuko KADOHIRA, Kei MIYAKOSHI, Mamoru TANAKA, Yasunori YOSHIMURA
- Organizer
  ENDO(米国内分泌学会)
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-20591305
[Presentation] ヒト胎児副腎の層形成機構におけるSyndecan-3の関与の可能性2009
- Author(s)
  峰岸一宏,石本人士,金善恵,浅井哲,田中守,青木大輔,吉村泰典
- Organizer
  第61回日本産科婦人科学会
- Place of Presentation
  国立京都国際会館
- Data Source
  KAKENHI-PROJECT-20591305
[Presentation] ヘパリン結合性成長因子Midkine のヒト胎児羊膜系における発現についての検討2008
- Author(s)
  樋口隆幸, 石本人士, 金善惠, 浅井哲, 峰岸一宏, 田中守, 青木大輔, 吉村泰典
- Organizer
  第60回日本産科婦人科学会学術講演会
- Place of Presentation
  横浜(パシフィコ横浜)
- Year and Date
  2008-04-15
- Data Source
  KAKENHI-PROJECT-19591288
[Presentation] Profile of Midkine, a Heparin-Binding Growth factor, in Human Amniotic Fluid and Amnion2008
- Author(s)
  Hitoshi Ishimoto, Takayuki Higuchi, et. al.
- Organizer
  The Society for Gynecologic Investigation, the 55th annual meeting
- Place of Presentation
  San Diego,USA
- Year and Date
  2008-03-27
- Data Source
  KAKENHI-PROJECT-19591288
[Presentation] Regulation of Expression of Angiotensin II Receptor Subtypes and ACTH Receptor by ACTH and Angiotensin II in Human Fetal Adrenal Cells2008
- Author(s)
  Ishimoto H, Minegishi K, Higuchi T, Asai S, Kim SH, Tanaka M, Yoshimura Y, Jaffe RB
- Organizer
  90th Annual Meeting of the Endocrine Society
- Place of Presentation
  San Francisco, USA
- Year and Date
  2008-06-17
- Data Source
  KAKENHI-PROJECT-19591288
[Presentation] ヘパリン結合性成長因子Midkineのヒト胎児羊膜系における発現についての検討2008
- Author(s)
  樋口隆幸, 石本人士ら.
- Organizer
  第60回日本産科婦人科学会学術講演会
- Place of Presentation
  横浜、パシフイコ横浜
- Year and Date
  2008-04-15
- Data Source
  KAKENHI-PROJECT-19591288
[Presentation] Profile of Midkine, a Heparin-Binding Growth Factor, in Human Amniotic Fluid and Amnion2008
- Author(s)
  Ishimoto H, Higuchi T, Minegishi K, Asai S, Kim SH, Tanaka M, Jaffe RB, Yoshimura Y.
- Organizer
  55th Annual Meeting of the Society for Gynecologic Investigation
- Place of Presentation
  San Diego, USA
- Year and Date
  2008-03-27
- Data Source
  KAKENHI-PROJECT-19591288
[Presentation] Expression profile of a heparin-binding growth factor, midkine, in human fetal tissues and the placenta2007
- Author(s)
  Higuchi T, Ishimoto H, Asai S, Minegishi K, Tanaka M, Yoshimura Y, Jaffe RB.
- Organizer
  89th Annual Meeting of the Endocrine Society
- Place of Presentation
  Toronto, Canada..
- Year and Date
  2007-06-04
- Data Source
  KAKENHI-PROJECT-19591288
[Presentation] Down-regulation of ACTH receptor gene expression by an ACTH-inducible heparin-binding growth factor, midkine in human fetal adrenal cells2007
- Author(s)
  Ishimoto H, Higuchi T, Asai S, Minegishi K, Tanaka M, Yoshimura Y, Jaffe RB
- Organizer
  89th Annual Meeting of the Endocrine Society
- Place of Presentation
  Toronto, Canada
- Year and Date
  2007-06-04
- Data Source
  KAKENHI-PROJECT-19591288
[Presentation] Placental expression profile and regulation of midkine a multifucntional growth/differentiation factor
- Author(s)
  Togo A, Kanno H, Narita A, Mitsuzuka K, Asai S, Nishimura O, Ishimoto H, Izumi S, Mikami M
- Organizer
  第67回日本産婦人科学会学術講演会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2015-04-10 – 2015-04-12
- Data Source
  KAKENHI-PROJECT-25461655
[Presentation] Expression of midkine in the human placenta:a possible role for early placental development
- Author(s)
  Togo A, Goto Y, Mitsuzuka K, Kanno H, Narita A, Asai S, Miyazawa M, Ishimoto H
- Organizer
  IFPA 2014 Paris（国際胎盤学会）
- Place of Presentation
  Paris, les Cordeliers
- Year and Date
  2014-09-09 – 2014-09-12
- Data Source
  KAKENHI-PROJECT-25461655

1. 亀谷美恵 (50338787)

# of Collaborated Projects: 6 results

# of Collaborated Products: 8 results
2. MINEGISHI Kazuhiro (30276331)

# of Collaborated Projects: 5 results

# of Collaborated Products: 8 results
3. GOTO Yumiko (50624574)

# of Collaborated Projects: 4 results

# of Collaborated Products: 10 results
4. HIGUCHI Takayuki (30365332)

# of Collaborated Projects: 3 results

# of Collaborated Products: 11 results
5. 三塚加奈子 (00514639)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
6. 柏木寛史 (10710460)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. YOSHIMURA Yashimura (10129736)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
8. ASAI Satoshi (70383867)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
9. TOGO Atsuko (20408024)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
10. TANAKA Mamoru (20207145)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
11. 宮澤昌樹 (30624572)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
12. JAFFE Robert B.

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
13. KONDO Akane (00384884)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
14. NISHIMURA Osamu (80296657)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
15. MIYAZAKI Toyohiko (20174162)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. SUEOKA Kou (90162833)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 菅野秀俊 (90631804)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 宮澤麻里子 (80637091)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 山本賢司 (10287071)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 岡宮稜子 (10908974)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 飯田哲士 (90439662)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 西島義博 (80453710)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 大岩一平 (50845732)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 百瀬浩晃 (30845665)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 平澤猛 (70307289)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 福田篤 (00638091)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 中林一彦 (10415557)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 阿久津英憲 (50347225)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 熊坂夏彦 (80525527)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. MUENCH Marcus O.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. ASAKO Otomo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
32. ITO Ryoji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

ISHIMOTO HITOSHI 石本 人士

HITOSHI Ishimoto 石本 人士

ISHIMOTO Hitoshi 石本 人士

石本 人士 イシモト ヒトシ

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胎児に由来する妊娠維持シグナルの調節機構と機能Principal Investigator

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Fetal signal-mediated maintenance of intrauterine environmentPrincipal Investigator

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Studies on pregnancy maintenance mediated by fetal and endocrine factorsPrincipal Investigator

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Fetoplacental factors involved in feto-maternal communications: who and howPrincipal Investigator

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ISHIMOTO HITOSHI 石本人士

HITOSHI Ishimoto 石本人士

ISHIMOTO Hitoshi 石本人士

石本人士イシモトヒトシ

[Book] 標準産科婦人科学第5版2021