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Komura Jun-ichiro  小村 潤一郎

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KOMURA Jun-ichiro  小村 潤一郎

小村 潤一郎  コムラ ジュンイチロウ

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Researcher Number 10215410
Affiliation (Current) 2025: 公益財団法人環境科学技術研究所, 生物影響研究部, 主任研究員
Affiliation (based on the past Project Information) *help 2014: 東北大学, 大学院医学系研究科, 助教
2011 – 2013: 東北大学, 医学(系)研究科(研究院), 助教
2009 – 2012: Tohoku University, 大学院・医学系研究科, 助教
2007: Tohoku University, Tohoku University, Graduate School of Medicine, Assistant Professor
2006: 東北大学, 大学院医学系研究科, 助手 … More
2000 – 2003: 東北大学, 大学院・医学系研究科, 助手
1993 – 1994: 東北大学, 医学部, 助手
1991: 東北大学, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
Molecular biology / Molecular biology / 環境影響評価(含放射線生物学) / Risk sciences of radiation and chemicals
Except Principal Investigator
Risk sciences of radiation/Chemicals / 老化(加齢)
Keywords
Principal Investigator
クロマチン / ionizing radiation / nucleosome / chromatin / 電離放射線 / ヌクレオソーム / DNA損傷 / gene activity / chromatin structure / 遺伝子発現 … More / 発現制御 / 遺伝子 / 遺伝子活性 / クロマチン構造 / 電解放射線 / psoralen / フットプリント / ソラレン / 細胞周期 / 機能 / 染色体構築 / 突然変異 / DNAメチル化 / 転写 … More
Except Principal Investigator
DNA損傷 / 紫外線 / cーmyc / DNAメチル化 / 遺伝子組換えマウス / 突然変異 / アポトーシス / MIS応答 / 皮膚 / 光化学反応 / 環境 / 光化学 / 光生物学 / 老化 / トランスジェニックマウス / 体細胞突然変異 / ラット / AER / 指趾奇形 / 5ーアザシチジン / 放射線 / DNAメチルトランスフェラ-ゼ / 肝腫瘍 / 老化と癌化 Less
  • Research Projects

    (12 results)
  • Research Products

    (19 results)
  • Co-Researchers

    (7 People)
  •  DNA修復とクロマチン動態の解析によるM期細胞の放射線高感受性の原因究明Principal Investigator

    • Principal Investigator
      小村 潤一郎
    • Project Period (FY)
      2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Risk sciences of radiation and chemicals
    • Research Institution
      Tohoku University
  •  Analysis of the mechanism of tissue-specific protection of skin against the genotoxicity of ultraviolet radiation

    • Principal Investigator
      IKEHATA Hironobu
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Risk sciences of radiation/Chemicals
    • Research Institution
      Tohoku University
  •  Demonstration of the formation of cyclobutane pyrimidine dimers through the excited triplet state mediated by solar UV radiation

    • Principal Investigator
      IKEHATA Hironobu
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Risk sciences of radiation/Chemicals
    • Research Institution
      Tohoku University
  •  Mechanisms of Epigenetic Inheritance in Condensed Mitotic ChromosomesPrincipal Investigator

    • Principal Investigator
      KOMURA Jun-ichiro
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Molecular biology
    • Research Institution
      Tohoku University
  •  Roles of chromatin structure in regulation of gene activityPrincipal Investigator

    • Principal Investigator
      KOMURA Jun-ichiro
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Molecular biology
    • Research Institution
      Tohoku University
  •  Translational and rotational positioning of nucleosomes and transcriptional regulationPrincipal Investigator

    • Principal Investigator
      KOMURA Jun-ichiro
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Molecular biology
    • Research Institution
      Tohoku University
  •  Influence of modification of DNA and histone on nucleosome positioningPrincipal Investigator

    • Principal Investigator
      KOMURA Jun-ichiro
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Molecular biology
    • Research Institution
      Tohoku University
  •  DNA損傷がエピジェネティックな変化を起こす機構Principal Investigator

    • Principal Investigator
      小村 潤一郎
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      環境影響評価(含放射線生物学)
    • Research Institution
      Tohoku University
  •  個体の老化に伴う遺伝的変化とエピジェネティックな変化の比較

    • Principal Investigator
      小野 哲也
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      老化(加齢)
    • Research Institution
      Tohoku University
  •  DNA損傷が転写を抑制する機構Principal Investigator

    • Principal Investigator
      小村 潤一郎
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      環境影響評価(含放射線生物学)
    • Research Institution
      Tohoku University
  •  分化、老化、癌化の過程で変化するDNAメチル化の生物学的意義

    • Principal Investigator
      小野 哲也
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Tohoku University
  •  指趾発生過程を指標にした催奇形性物質スクリ-ニング法の開発

    • Principal Investigator
      栗下 昭弘
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tohoku University

All 2012 2011 2010 2009 2007 Other

All Journal Article Presentation Book

  • [Book] ゲノムの加齢変化2010

    • Author(s)
      小野哲也、上原芳彦、小村潤一郎
    • Publisher
      東京大学
    • Data Source
      KAKENHI-PROJECT-21570177
  • [Journal Article] Fully functional global genome repair of(6-4)photoproducts and compromised transcription-coupled repair of cyclobutane pyrimidine dimers in condensed mitotic chromatin2012

    • Author(s)
      Komura J, Ikehata H, Mori T, Ono T
    • Journal Title

      Exp Cell Res

      Volume: 318 Pages: 623-631

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21570177
  • [Journal Article] Fully functional global genome repair of (6-4) photoproducts and compromised transcription-coupled repair of cyclobutane pyrimidine dimers in condensed mitotic chromatin2012

    • Author(s)
      J.Komura
    • Journal Title

      Exp.Cell Res.

      Volume: 318 Issue: 5 Pages: 623-631

    • DOI

      10.1016/j.yexcr.2012.01.003

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21570177, KAKENHI-PROJECT-23510081, KAKENHI-PROJECT-23651044
  • [Journal Article] 活性遺伝子のクロマチン微細構造のM期における変化に関する研究2011

    • Author(s)
      小村潤一郎
    • Journal Title

      東北医学雑誌

      Volume: 123 (1) Pages: 37-39

    • Data Source
      KAKENHI-PROJECT-21570177
  • [Journal Article] Effects of calorie restriction on the age-dependent accumulation of mutations in the small intestine of lacZ-transgenic mice2011

    • Author(s)
      He D, Uehara Y, Furuya M, Ikehata H, Komura J, Yamauchi K, Kakinuma S, Shang Y, Shimada Y, Ootsuyama A, Norimura T, Ono T
    • Journal Title

      Mech Age Dev

      Volume: 132 Pages: 117-122

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21570177
  • [Journal Article] XPC is involved in genome maintenance through multiple pathways in different tissues2009

    • Author(s)
      Uehara Y, Ikehata H, Furuya M, Kobayashi S, He D, Chen Y, Komura J, Ohtani H, Shimokawa I, Ono T
    • Journal Title

      Mutat Res

      Volume: 670 Pages: 24-31

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21570177
  • [Journal Article] Chromatin fine structure of the c-MYC insulator element/DNase I-hypersensitive site I is not preserved during mitosis.2007

    • Author(s)
      Jun-ichiro Komura
    • Journal Title

      Proc. Natl. Acad. Sci. USA 104

      Pages: 15741-15746

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18570158
  • [Journal Article] Chromatin fine structure of the c-MYC insulator element/DNase l-hypersensitivesite I is not preserved during mitosis2007

    • Author(s)
      Jun-ichiro Komura
    • Journal Title

      Proc. Natl. Acad. Sci. USA 104

      Pages: 15741-15746

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18570158
  • [Journal Article] Chromatin fine structure of the c-MYC insulator element/DNase I-hypersensitive site I is not preserved during mitosis.2007

    • Author(s)
      Jun-ichiro Komura
    • Journal Title

      Proceedings of the National Academy of Sciences 104

      Pages: 15741-15746

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18570158
  • [Presentation] M期の凝縮した染色体におけるDNA二本鎖切断の修復とその影響2012

    • Author(s)
      小村潤一郎, 池畑広伸, 小野哲也
    • Organizer
      日本放射線影響学会第55回大会
    • Place of Presentation
      仙台市
    • Year and Date
      2012-09-08
    • Data Source
      KAKENHI-PROJECT-24310036
  • [Presentation] M期の凝縮した染色体におけるDNA二本鎖切断の修復とその影響2012

    • Author(s)
      小村潤一郎、池畑広伸、小野哲也
    • Organizer
      影響学会第55回大会
    • Place of Presentation
      仙台
    • Year and Date
      2012-09-08
    • Data Source
      KAKENHI-PROJECT-23651044
  • [Presentation] M期の凝縮した染色体におけるDNA修復:効率的なゲノム全体の除去修復と不活性な転写共役修復2011

    • Author(s)
      小村潤一郎
    • Organizer
      日本放射線影響学会第54回大会
    • Place of Presentation
      神戸商工会議所会館
    • Year and Date
      2011-11-18
    • Data Source
      KAKENHI-PROJECT-21570177
  • [Presentation] M期の凝縮した染色体におけるDNA修復:効率的なゲノム全体の修復と不活性な転写共役修復2011

    • Author(s)
      小村潤一郎、池畑広伸、森俊雄、小野哲也
    • Organizer
      日本放射線影響学会第54回大会
    • Place of Presentation
      神戸商工会議所会館
    • Year and Date
      2011-11-18
    • Data Source
      KAKENHI-PROJECT-21570177
  • [Presentation] 放射線誘発突然変異のエイジ依存性2011

    • Author(s)
      小野哲也、上原芳彦、池畑広伸、小村潤一郎
    • Organizer
      日本放射線影響学会第54回大会
    • Place of Presentation
      神戸商工会議所会館
    • Year and Date
      2011-11-18
    • Data Source
      KAKENHI-PROJECT-21570177
  • [Presentation] M期の凝縮した染色体におけるDNA修復:効率的なゲノム全体の除去修復と不活性な転写共役修復2011

    • Author(s)
      小村潤一郎、池畑広伸、森俊雄、小野哲也
    • Organizer
      影響学会第54回大会
    • Place of Presentation
      神戸
    • Year and Date
      2011-11-18
    • Data Source
      KAKENHI-PROJECT-23651044
  • [Presentation] M期細胞における効率的なDNA修復2010

    • Author(s)
      小村潤一郎、池畑広伸、森俊雄、小野哲也
    • Organizer
      日本放射線影響学会第53回大会
    • Place of Presentation
      京都テルサ
    • Year and Date
      2010-10-22
    • Data Source
      KAKENHI-PROJECT-21570177
  • [Presentation] 水素ガスの放射線防護効果2010

    • Author(s)
      古谷真衣子、小野哲也、小村潤一郎、上原芳彦、地元祐輔、仲田栄子、高井良尋、大澤郁朗
    • Organizer
      日本放射線影響学会第53回大会
    • Place of Presentation
      京都テルサ
    • Year and Date
      2010-10-22
    • Data Source
      KAKENHI-PROJECT-21570177
  • [Presentation] M期細胞における効率的なDNA修復2010

    • Author(s)
      小村潤一郎
    • Organizer
      日本放射線影響学会第53回大会
    • Place of Presentation
      京都テルサ(京都市)
    • Year and Date
      2010-10-22
    • Data Source
      KAKENHI-PROJECT-21570177
  • [Presentation] M期の凝縮した染色体におけるDNA二本鎖切断の修復とその影響

    • Author(s)
      小村潤一郎、池畑広伸、小野哲也
    • Organizer
      日本放射線影響学会第55回大会
    • Place of Presentation
      仙台市
    • Data Source
      KAKENHI-PROJECT-23651044
  • 1.  IKEHATA Hironobu (90250737)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 4 results
  • 2.  小野 哲也 (00107509)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 3.  栗下 昭弘 (60201472)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  MORI Toshio (10115280)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  AIBA Setsuya
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  KAMEI Yasuhiro
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  HIGASHI Shoichi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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