Yanagisawa Katsuhiko 柳澤勝彦

… Alternative Names

Researcher Number	10230260
Other IDs
Affiliation (Current)	2019: 国立研究開発法人国立長寿医療研究センター, その他部局等, その他
Affiliation (based on the past Project Information) *help	2011 – 2012: 独立行政法人国立長寿医療研究センター, 研究所, 副所長 2009 – 2010: National Institute for Longevity Sciences,NCGG, 副所長 2006 – 2009: National Institute for Longevity Sciences,NCGG, 副所長 2004 – 2005: Natl Inst for Longevity Sci., Dept of Alzheimer's Disease Research, Head, (研究所), 副所長 2003: 国立長寿医療センター, (研究所)・アルツハイマー病研究部, 部長 … More
Review Section/Research Field	Principal Investigator Biological Sciences / Neurochemistry/Neuropharmacology / Nerve anatomy/Neuropathology Except Principal Investigator Neurochemistry/Neuropharmacology / Neurology / Nerve anatomy/Neuropathology
Keywords	Principal Investigator アルツハイマー病 / 老人斑 / アミロイド蛋白 / シナプス / アミロイドβ蛋白 / アポリポ蛋白E / ガングリオシド / マイクロドメイン / 遺伝的変異型 / 質量分析 … More Except Principal Investigator hn cDNA / アルツハイマー病 / 定量 / dementia / senile plaque / 副腎白質ジストロフィー / animal model / 副賢白質ジストロフィー / XQ28 / 痴呆 / amyloidbeta-protein / コスミドクローン / Alzheimer's disease / REVERSE GENETICS / 動物モデル / β蛋白 / preamyloid / ADRENOLEUKODYSTROPHY / X CHROMOSOME / Xq28 / 老人斑 / Alzheimer's Disease / diffuse plaque / Xg28 / アミロイドβ蛋白 / β-amylodogenesis / HEREDITARY NEURODEGENERATIVE DISEASE / アポE / COSMID CLONES / 髄膜 / クロ-ニング / raft / POSITIONAL CLONING / ポジショナルクローニング / ポジショナルクロ-ニング / amyloid / 遺伝学 / ゲノム / アミロイド / ApoE / GM1ガングリオシド / 遺伝性神経疾患 / 脂質ラフト / リバ-スジェネティックス / リバースジュネティックス / X染色体 Less

Study on molecular mechanism underlying brain region-specific Ass depositionPrincipal Investigator
- Principal Investigator
  
  YANAGISAWA Katsuhiko
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  National Center for Geriatrics and Gerontology
Molecular mechanism underlying Ass assembly in Alzheimer brain : pathological and therapeutic significance of an endogenous seed for amyloidPrincipal Investigator
- Principal Investigator
  
  YANAGISAWA Katsuhiko
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  National Institute for Longevity Sciences,NCGG
Influence of membrane lipid metabolism on cerebral amyloid deposition and neurodegeneration.
- Principal Investigator
  
  YAMAGUCHI Haruyasu
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Gunma University
An investigation into molecular mechanism underlying Aβ assemblyPrincipal Investigator
- Principal Investigator
  
  YANAGISAWA Katsuhiko
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  National Institute for Longevity Sciences
アルツハイマー病脳におけるアミロイドβ蛋白蓄積の初期機構に関する生化学的研究Principal Investigator
- Principal Investigator
  
  柳澤勝彦
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  The University of Tokyo
Studies on beta-amyloidogenesis-isolation of membrane-bound Abeta
- Principal Investigator
  
  IHARA Yasuo
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  University of Tokyo
POSITIONAL CLONING OF CANDIDATE GENES
- Principal Investigator
  
  MIYATAKE Tadashi
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  Neurology
- Research Institution
  TOKYO MEDICAL AND DENTAL UNIVERSITY

All 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001 Other

All Journal Article Presentation Book

[Book] Amyloid, arises on the membranes and acts on the membranes. In : Amyloids: Composition, Function and Pathology2012
- Author(s)
  Yanagisawa K.
- Publisher
  edited by Irene P. Halcheck and Nancy R. Vernon: published by Nova Science Publishers, Inc.
- Data Source
  KAKENHI-PROJECT-22300118
[Book] Amyloid, arises on the membranes and acts on the membranes. In:Amyloids: Composition, Function and Pathology (edited by Irene P. Halcheck and Nancy R. Vernon)2012
- Author(s)
  Yanagisawa K.
- Publisher
  Nova Science Publishers, Inc.
- Data Source
  KAKENHI-PROJECT-22300118
[Book] Research Progress in Alzheimer's Disease(edited by Miao-Kun Sun, Pivotal roles of cholesterol and gangliosides in aggregation of amyloid β-protein.)2010
- Author(s)
  Yanagisawa K.
- Publisher
  Nova Science Pulishers, Inc.(in press)
- Data Source
  KAKENHI-PROJECT-17025057
[Book] Comprehensive Glycoscience(edited by Kamerling J.P., Boons G-J., Lee Y.C.,Suzuki A. and Taniguchi N., Glycoconjugates and neurological diseases.)2007
- Author(s)
  Yanagisawa K, Yuki N.
- Publisher
  Elsevier
- Data Source
  KAKENHI-PROJECT-17025057
[Book] Comprehensive Glycoscience2007
- Author(s)
  Yuki N & Yanagisawa K.
- Publisher
  Elsevier
- Data Source
  KAKENHI-PROJECT-17025057
[Book] Ganglioside and Alzheimer's Disease. In: Sphingolipid Biology2006
- Author(s)
  Yanagisawa K.
- Publisher
  Springer-Verlag, Tokyo
- Data Source
  KAKENHI-PROJECT-17025057
[Book] Sphingolipid Biology.(edited by Hirabayashi Y, Igarashi Y and Merill AH, Ganglioside and Alzheimer's disease.)2006
- Author(s)
  Yanagisawa K.
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-17025057
[Book] Pivotal roles of cholesterol and gangliosides in aggregation of amyloid β-protein. Research Progress in Alzheimer's Disease Interactions.2005
- Author(s)
  Yanagisawa K.
- Publisher
  Nova Science Publisher, Inc, New York(印刷中)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12210022
[Book] Cholesterol and Aβ fibrillogenesis. In : Subcellular Biochemistry : Alzheimer's disease-Cellular2005
- Author(s)
  Yanagisawa K.
- Publisher
  Springer-Verlag Heidelberg Germany
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12210022
[Book] Cholesterol and Aβ cascade : pathological implication of apolipoprotein E in Alzheimer's disease.2005
- Author(s)
  Yanagisawa K.
- Publisher
  The Patherson Publishing Group
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12210022
[Book] Cholesterol and amyloid β fibrillogenesisIn: Alzheimer's Disease: Cellular and Molecular Aspects of Amyloid β(edited by Robin Harris and Falk Fahrenholz)2005
- Author(s)
  Yanagisawa, K.
- Publisher
  Springer-Verlag
- Data Source
  KAKENHI-PROJECT-17025057
[Book] Cholesterol and Aβ fibrillogenesis.In : Subcellular Biochemistry : Alzheimer' s disease-Cellular2005
- Author(s)
  Yanagisawa K.
- Publisher
  Springer-Verlag(印刷中)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12210022
[Book] Cholesterol and amyloid β fibrillogenesis. In : Alzheimer's Disease : Cellular and Molecular Aspects of Amyloid β.2005
- Author(s)
  Yanagisawa K.
- Total Pages
  409
- Publisher
  Springer-Verlag, Heidelberg, Germany
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12210022
[Book] Cholesterol and Aβ fibrillogenesis. In : SubcelluIar Biochemistry : Alzheimer's disease-Cellular and moleculer aspects of amyloid.2005
- Author(s)
  Yanagisawa K.
- Publisher
  Springer-Vierlag
- Data Source
  KAKENHI-PROJECT-17025057
[Book] Pivotal roles of cholesterol and gangliosides in aggregation of Amyloid β-protein. Research Progress in Alzheimer's Disease Interactions.2005
- Author(s)
  Yanagisawa K.
- Publisher
  Nova Science Publishers, Inc. New York, U.S.A.
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12210022
[Book] Cholesterol and Aβ cascade : pathological implication of apolipoprotein E in Alzheimer's disease.2005
- Author(s)
  Yanagisawa K.
- Publisher
  The Patherson Publishing Group(印刷中)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12210022
[Book] Recent Progress in Alzheimer's and Parkinsons's Diseases(edited by Hanin I,Casabelos R and Fisher A, Cholesterol and Aβ cascade:pathological implication of apolipoprotein E in Alzheimer's disease.)2005
- Author(s)
  Yanagisawa K.
- Publisher
  Taylor & Francis
- Data Source
  KAKENHI-PROJECT-17025057
[Book] Cholesterol and amyloid β fibrillogenesis. In : Alzheimer's Disease : Cellular and Molecular Aspects of Amyloid β.2005
- Author(s)
  Yanagisawa K.
- Publisher
  Springer-Verlag Heidelberg Germany
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12210022
[Book] Possible link between cholesterol and dementia, depression. In : Cognition and Mood.2005
- Author(s)
  Yanagisawa K.
- Publisher
  Nova Science Publishers, Inc. New York, U.S.A
- Data Source
  KAKENHI-PROJECT-17025057
[Book] Possible link between cholesterol and dementia, depression.In : Cognition and Mood2005
- Author(s)
  Yanagisawa K.
- Publisher
  Nova Science Publishers, Inc. New York, U.S.A(印刷中)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12210022
[Book] Cholesterol and amyloid β fibrillogenesis. In : Alzheimer's Disease : Cellular and Molecular Aspects of Amyloid β.2005
- Author(s)
  Yanagisawa K.
- Total Pages
  409
- Publisher
  Springer-Verlag, Heidelberg, Germany
- Data Source
  KAKENHI-PROJECT-17025057
[Book] Possible link between cholesterol and dementia, depression.In : Cognition and Mood2005
- Author(s)
  Yanagisawa K.
- Publisher
  Nova Science Publishers, Inc. New York, U.S.A.
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12210022
[Book] Cholesterol and Aβ cascade : pathological implication of apolipoprotein E in Alzheimer's and Parkinson's disease.2005
- Author(s)
  Yanagisawa K.
- Publisher
  The Patherson Publishing Group
- Data Source
  KAKENHI-PROJECT-17025057
[Book] Amyloidogenesis and cholesterol. In : Mapping the Progress of Alzheimer's disease and Parkinson's disease.2002
- Author(s)
  Yanagisawa K. et al.
- Publisher
  Kluwer Academic/Plenum Publishers
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12210022
[Book] Amyloidogenesis and cholesterol. In : Mapping the Progress of Alzheimer's disease and Parkinson's disease.2002
- Author(s)
  Yanagisawa K.他
- Total Pages
  565
- Publisher
  Kluwer Academic/Plenum Publishers
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12210022
[Journal Article] The density of GM1 in nanoclusters is a critical factor in the formation of a spherical assembly of amyloid β-protein on synaptic plasma membranes, T. Matsubara, K. Iijima, N. Yamamoto2013
- Author(s)
  Teruhiko Matsubara, Kazutoshi Iijima, Naoki Yamamoto, Katsuhiko Yanagisawa, and Toshinori Sato
- Journal Title
  
  Langmuir
  
  Volume: 29(7) Pages: 2258-2264
- DOI
  10.1021/la3038999
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300118, KAKENHI-PROJECT-23241075
[Journal Article] Lysosomal dysfunction in a mouse model of Sandhoff disease leads to accumulation of ganglioside-bound amyloid-ss peptide2012
- Author(s)
  Keilani S., Lun Y., Stevens A.C., Williams H.N., Sjoberg E.R., Khanna R., Valenzaro K.J., Checler F., Buxbaum J.D., Yanagisawa K., Lockhart D.J., Wustman B.A. and Gandy S.
- Journal Title
  
  J Neurosci.
  
  Volume: 32 Pages: 5223-5236
- DOI
  10.1523/jneurosci.4860-11.2012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300118
[Journal Article] アミロイド蓄積開始機構の解明と治療薬開発への展開2012
- Author(s)
  柳澤勝彦、松崎勝巳、加藤晃一
- Journal Title
  
  最新医学
  
  Volume: 67(第48回ベルツ賞受賞論文) Pages: 138-158
- Data Source
  KAKENHI-PROJECT-22300118
[Journal Article] The γ-secretase inhibitor DAPT increases the levels of gangliosides at neuritic terminals of differentiating PC12 cells.2012
- Author(s)
  Oikawa N., Goto M., Ikeda K., Taguchi R. and Yanagisawa K.
- Journal Title
  
  Neurosci Lett
  
  Volume: 525 Pages: 49-53
- DOI
  10.1016/j.neulet.2012.07.027
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300118, KAKENHI-PROJECT-24619007
[Journal Article] Spectroscopic characterization of inter-molecular interaction of amyloid beta promoted on GM1 micelles2011
- Author(s)
  Yagi-Utsumi M. et al. (Yanagisawa K., Kato K.)
- Journal Title
  
  International Journal of Alzheimer's Disease
  
  Volume: 2011
- DOI
  10.4061/2011/925073
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300118, KAKENHI-PROJECT-22870021
[Journal Article] Pathological significance of ganglioside clusters in Alzheimer's disease.2011
- Author(s)
  Yanagisawa K.
- Journal Title
  
  J Neurochem.
  
  Volume: 116 Pages: 806-812
- DOI
  10.1111/j.1471-4159.2010.07006.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300118
[Journal Article] Ass behavior on neuronal membranes : aggregation and toxicities2011
- Author(s)
  Yanagisawa K.
- Journal Title
  
  International Journal of Alzheimer's Disease
  
  Volume: (Editorial)
- DOI
  10.4061/2011/286536
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300118
[Journal Article] Extracellular and intraneuronal HMW-AbetaOs represent a molecular basis of memory loss in Alzheimer's disease model mouse.2011
- Author(s)
  Takamura A, Okamoto Y, Kawarabayashi T, Yokoseki T, Shibata M, Mouri A, Nabeshima T, Sun H, Abe K, Urisu T, Yamamoto N, Shoji M, Yanagisawa K, Michikawa M, Matsubara E
- Journal Title
  
  Molecular Neurodegeneration
  
  Volume: 6 Pages: 1-16
- DOI
  10.1186/1750-1326-6-20
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591069, KAKENHI-PROJECT-22300118, KAKENHI-PROJECT-23659449, KAKENHI-PROJECT-23659450
[Journal Article] Gender effect on the accumulation of hyperphosphorylated tau in the brains of locus-ceruleus-injured APP transgenic mouse2010
- Author(s)
  Oikawa N, Ogino K, Masumoto T, Yamaguchi H, Yanagisawa K.
- Journal Title
  
  Neurosci. Lett. 468
  
  Pages: 243-247
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17025057
[Journal Article] Ass polymerization through interaction with membrane gangliosides.2010
- Author(s)
  Matsuzaki K, (Yanagisawa K), et al.
- Journal Title
  
  Biochim Biophys Acta
  
  Volume: 1801 Pages: 868-877
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300118
[Journal Article] Surface-induced phase separation of a sphingomyelin/cholesterol/ganglioside GM1-planar bilayer on mica surfaces and microdomain molecular conformation that accelerates Ass oligomerization.2010
- Author(s)
  Mao Y, (Yamamoto N, Yanagisawa K), et al.
- Journal Title
  
  Biochim Biophys Acta
  
  Volume: 1798 Pages: 1090-1099
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300118
[Journal Article] Alzheimer-type tau pathology in advanced nonhuman primate brains harboring substantial amyloid depositio2010
- Author(s)
  Oikawa N, Kimura N, Yanagisawa K.
- Journal Title
  
  Brain. Res. 1315
  
  Pages: 137-149
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17025057
[Journal Article] Sphingomyelin accumulation provides a favorable milieu for GM1 ganglioside-induced assembly of amyloid ss-protein.2010
- Author(s)
  Yuyama K, (Yanagisawa K), et al.
- Journal Title
  
  Neurosci Lett
  
  Volume: 481 Pages: 168-172
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300118
[Journal Article] Alzheimer-type tau pathology in advanced aged nonhuman primate brainsharboring substantial amyloid deposition.2010
- Author(s)
  Oikawa N, (Yanagisawa K), et al.
- Journal Title
  
  Brain research 1315
  
  Pages: 137-149
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17025057
[Journal Article] Surface-induced phase separation of a sphingomyelin / cholesterol / ganglioside GM1-planar bilayer on mica surfaces and microdomain molecular conformation that accelerates As oligomerization2010
- Author(s)
  Mao Y, Zhiguo S, Imai Y, Hoshino T, Tero R, Tanaka M, Yamamoto N, Yanagisawa K, Urisu T.
- Journal Title
  
  Biochim Biophys Acta (in press)
  
  Pages: 22-26
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17025057
[Journal Article] A polymerization through interaction with membrane gangliosides2010
- Author(s)
  Matsuzaki K(Yanagisawa K), et al.
- Journal Title
  
  Biochim Biophys Acta (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17025057
[Journal Article] Gender effect on the accumulation of hyperphosphorylated tau in the brain of locus-ceruleus-injured APP-transgenic mouse.2010
- Author(s)
  Oikawa N, (Yanagisawa K), et al.
- Journal Title
  
  Neuroscience letters 468
  
  Pages: 243-247
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17025057
[Journal Article] Surface-induced phase sepaiation of a sphingomyelin/cholesterol/ganglioside GM1-planar bilayer on mica surfaces and microdomain molecular conformation that accelerates Ass oligomerization.2010
- Author(s)
  Mao Y(Yanagisawa K), et al.
- Journal Title
  
  Biochim Biophys Acta (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17025057
[Journal Article] Pathological significance of ganglioside clusters in Alzheimer's disease.2010
- Author(s)
  Yanagisawa K.
- Journal Title
  
  J Neurochem
  
  Volume: 116 Pages: 806-812
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300118
[Journal Article] Ass polymerization through interaction with membrane gangliosides.2010
- Author(s)
  Matsuzaki K, Kato K, Yanagisawa K
- Journal Title
  
  Biochim Biophys Acta
  
  Volume: 1801(8) Pages: 868-877
- DOI
  10.1016/j.bbalip.2010.01.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300118
[Journal Article] Up-and-down topological mode of amyloid β-peptide lying on hydrophilic/hydrophobic interface of ganglioside clusters.2009
- Author(s)
  Utsumi M, (Yanagisawa K), et al.
- Journal Title
  
  Glycoconjugate J (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17025057
[Journal Article] Late endocytic dysfunction as a putative cause of amyloid fibril formation in Alzheimer's disease.2009
- Author(s)
  Yuyama K, Yanagisawa K.
- Journal Title
  
  J Neurochem (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17025057
[Journal Article] Gangliosides determine the amyloid pathology of Alzheimer's disease.2009
- Author(s)
  Oikawa N, (Yanagisawa K), et al.
- Journal Title
  
  Neuroreport 20
  
  Pages: 1043-1046
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17025057
[Journal Article] Depletion of vitamin E increases amyloid beta accumulation by decreasing its clearances from brain and blood in a mouse model of Alzheimer disease.2009
- Author(s)
  Nishida Y, (Yanagisawa K), et al.
- Journal Title
  
  The Journal of biological chemistry 284
  
  Pages: 33400-33408
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17025057
[Journal Article] Bioactive TGF-beta can associate with lipoproteins and is enriched in those containing apolipoprotein E3.2009
- Author(s)
  Tesseur I, (Yanagisawa K), et al.
- Journal Title
  
  Journai of neurochemistry 110
  
  Pages: 1254-1262
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17025057
[Journal Article] ate endocytic dysfunction as a putative cause of amyloid fibril formation in Alzheimer's disease2009
- Author(s)
  Yuyama., Yanagisawa K.
- Journal Title
  
  J. Neurochem 109
  
  Pages: 1250-1260
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17025057
[Journal Article] Gangliosides determine the amyloid pathology of Alzheimer disease.2009
- Author(s)
  Oikawa N, (Yanagisawa K), et al.
- Journal Title
  
  Neuroreport (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17025057
[Journal Article] Late endocytic dysfunction as a putative cause of amyloid fibril formation in Alzheimer's disease.2009
- Author(s)
  Yuyama K, (Yanagisawa K)
- Journal Title
  
  Journal of neurochemistry 109
  
  Pages: 1250-1260
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17025057
[Journal Article] Gangliosides determine the amyloid pathology of Alzheimer disease2009
- Author(s)
  Oikawa N, Yamaguchi H, Ogino K, Taki T, Yuyama K, Yamamoto N, Shin R-W., Furukawa K, Yanagisawa K.
- Journal Title
  
  Neuroreport 20
  
  Pages: 143-1046
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17025057
[Journal Article] Up-and-down topological mode of amyloid beta-peptide lying on hydrophilic/hydrophobic interface of ganglioside clusters.2009
- Author(s)
  Utsumi M, (Yanagisawa K), et al.
- Journal Title
  
  Glycoconjugate journal 26
  
  Pages: 999-1006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17025057
[Journal Article] Up-and-down topological mode of amyloid s-peptide lying on hydrophilic / hydrophobic interface of ganglioside clusters2009
- Author(s)
  Utsumi M, Yamaguchi Y, Sasakawa H, Yamamoto N, Yanagisawa K, Kato K.
- Journal Title
  
  Glycoconjugate J. 26
  
  Pages: 999-1006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17025057
[Journal Article] ate endocytic dysfunction as a putative cause of amyloid fibril formation in Alzheimer's disease2009
- Author(s)
  Yuyama K, Yanagisawa K.
- Journal Title
  
  J. Neurochem 109
  
  Pages: 1250-1260
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17025057
[Journal Article] Novel role of presenilins in maturation and transport of integrin β1.2008
- Author(s)
  Zou K, (Yanagisawa K) et al.
- Journal Title
  
  Biochemistry 47
  
  Pages: 3370-3378
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17025057
[Journal Article] Age-dependent high-density clustering of GM1 ganglioside at presynaptic neuritic terminals promotes amyloid s-protein fibrillogenesis2008
- Author(s)
  Yamamoto N, Matusbara T, Sato T. Yanagisawa K.
- Journal Title
  
  Biochim. Biophys. Acta 1778
  
  Pages: 2717-2726
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17025057
[Journal Article] Novel role of presenilins in maturation and transport of integrin β1.2008
- Author(s)
  Zou K, (Yanagisawa K), et al.
- Journal Title
  
  Biochemistry 47
  
  Pages: 3370-3378
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17025057
[Journal Article] ccelerated release of exosome-associated GM1 ganglioside (GM1) by endocytic pathway abnormality: another putative pathway for GM1-induced amyloid fibril formation2008
- Author(s)
  Yuyama K, Yamamoto N, Yanagisawa K.
- Journal Title
  
  J. Neurochem 105
  
  Pages: 217-224
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17025057
[Journal Article] Age-dependent high-density clustering of GM1 ganglioside at presynaptic neuritic terminals promotes amyloid β-protein fibrillogenesis.2008
- Author(s)
  Yamamoto N, (Yanagisawa K), et al.
- Journal Title
  
  Biochim Biophys Acta 1778
  
  Pages: 2717-2726
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17025057
[Journal Article] Accelerated release of exosome-associated GM1 ganglioside (GM1) by endocytic pathway abnormality : another putative pathway for GM1-induced amyloid fibril formation.2008
- Author(s)
  Yuyama K, (Yanagisawa K) et al.
- Journal Title
  
  J. Neurochem 105
  
  Pages: 217-214
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17025057
[Journal Article] A ganglioside -induced toxic soluble As assembly: Its enhanced formation from As bearing theArctic mutation2007
- Author(s)
  amamoto N, Matsubara E, Maeda S, Minagawa H, Takashima A, Maruyama W, Michikawa M, Yanagisawa, K.
- Journal Title
  
  J. Biol. Chem 282
  
  Pages: 2646-2656
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17025057
[Journal Article] A ganglioside-induced toxic soluble Aβ assembly: Its enhanced formation from Aβ bearing the Arctic mutation.2007
- Author(s)
  Yamamoto N, (Yanagisawa K), et. al.
- Journal Title
  
  J Biol Chem 282
  
  Pages: 2646-2655
- Data Source
  KAKENHI-PROJECT-17025057
[Journal Article] GM1-ganglioside-induced Aβ assembly on synaptic membranes of culturedneurons.2007
- Author(s)
  Yamamoto N, (Yanagisawa K), et. al.
- Journal Title
  
  Biochim Biophys Acta 1768
  
  Pages: 1128-1137
- Data Source
  KAKENHI-PROJECT-17025057
[Journal Article] Angiotensin-converting enzyme converts Aβ1-42 to Aβ1-40 and its inhibition enhances brain Aβ deposition.2007
- Author(s)
  Zou K, (Yanagisawa K) et al,
- Journal Title
  
  J. Neurosci. 27
  
  Pages: 8628-8635
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17025057
[Journal Article] Novel action of apolipoprotein E (ApoE) : ApoE isoform specifically inhibits lipid-particle-mediated cholesterol release from neurons.2007
- Author(s)
  Gong J, (Yanagisawa K) et al.
- Journal Title
  
  Molecular Neurodegeneration 2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17025057
[Journal Article] GM1-ganglioside-induced Aβ assembly on synaptic membranes of cultured neurons.2007
- Author(s)
  Yamamoto N, (Yanagisawa K) et al.
- Journal Title
  
  Biochim. Biophys. Acta 1768
  
  Pages: 1128-1137
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17025057
[Journal Article] GM1-ganglioside-induced As assembly on synaptic membranes of cultured neurons2007
- Author(s)
  Yamamoto N, Fukata Y, Fukata M, Yanagisawa K.
- Journal Title
  
  Biochim. Biophys. Acta 1768
  
  Pages: 1128-1137
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17025057
[Journal Article] Role of gangliosides in Alzheimer's disease.2007
- Author(s)
  Yanagisawa K.
- Journal Title
  
  Biochim. Biophys. Acta 1768
  
  Pages: 1943-1951
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17025057
[Journal Article] Endosomal accumulation of GM1-ganglioside-bound amyloid β-protein inneurons of aged monkey brains.2007
- Author(s)
  Kimura N & Yanagisawa K.
- Journal Title
  
  Neuroreport 18
  
  Pages: 1669-1673
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17025057
[Journal Article] Chloroquine-induced endocytic pathway abnormalities: cellular model of GM1 -ganglioside-induced As fibrillogenesis in Alzheimer's disease2006
- Author(s)
  Yuyama K, Yamamoto N, Yanagisawa K.
- Journal Title
  
  FEBS Lett 580
  
  Pages: 6972-6976
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17025057
[Journal Article] Chloroquine-induced endocytic pathway abnormalities: Cellular model of GM1 ganglioside-induced Aβ fibrillogenesis in Alzheimer's disease.2006
- Author(s)
  Yuyama K, (Yanagisawa K), et. al.
- Journal Title
  
  FEBS Lett 580
  
  Pages: 6972-6976
- Data Source
  KAKENHI-PROJECT-17025057
[Journal Article] Further evidence of local ganglioside-dependent amyloid β-protein assembly in brain.2006
- Author(s)
  Yamamoto N, (Yanagisawa K), et. al.
- Journal Title
  
  Neuroreport 17
  
  Pages: 1735-1737
- Data Source
  KAKENHI-PROJECT-17025057
[Journal Article] Murine synaptosomal lipid raft protein and lipid composition are altered by expression of human apoE 3 and 4 and by increasing age.2005
- Author(s)
  Igbavboa U, (Yanagisawa K) et al.
- Journal Title
  
  J Neurol Sci 229
  
  Pages: 225-232
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12210022
[Journal Article] Age-related changes of intracellular Aβ in cynomolgus monkey brains.2005
- Author(s)
  Kimura N, (Yanagisawa K) et al.
- Journal Title
  
  Neuropathol Applied Neurobiol 31
  
  Pages: 170-180
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12210022
[Journal Article] Cross-seeding of wild- and hereditary variant-type amyloid β-proteins in the presence of gangliosides.2005
- Author(s)
  Yamamoto N, (Yanagisawa K) et al.
- Journal Title
  
  J Neurochem 95
  
  Pages: 1167-1176
- Data Source
  KAKENHI-PROJECT-17025057
[Journal Article] Suppression of Aβ deposition in brain by peripharal administration of Fab fragments of anti-seed antibody.2005
- Author(s)
  Yamamoto N, (Yanagisawa K) et al.
- Journal Title
  
  Biochem Biophys Res Commun 335
  
  Pages: 45-47
- Data Source
  KAKENHI-PROJECT-17025057
[Journal Article] Altered cholesterol metabolism in Niemann-Pick type C mouse brains affectsmitochondrial function.2005
- Author(s)
  Yu W, (Yanagisawa K) et al.
- Journal Title
  
  J Biol Chem 280
  
  Pages: 11731-11739
- Data Source
  KAKENHI-PROJECT-17025057
[Journal Article] Altered cholesterol metabolism in Niemann-Pick Type C1 mouse brain affects mitochondria function.2005
- Author(s)
  Yu W, (Yanagisawa K) et al.
- Journal Title
  
  J Biol Chem 280
  
  Pages: 11731-11739
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12210022
[Journal Article] Age-related changes of intracellular Aβ in cynomolgus monkey brains.2005
- Author(s)
  Kimura N, (Yanagisawa K) et al.
- Journal Title
  
  Neuropath Applied Neurobiol 31
  
  Pages: 170-180
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12210022
[Journal Article] Suppression of As deposition in brain by peripheral administration of Fab fragments of anti-seed antibody2005
- Author(s)
  Yamamoto N, Yokoseki T, Shibata M, Yamaguchi H, Yanagisawa K.
- Journal Title
  
  Biochem. Biophys. Res. Commun. 335
  
  Pages: 45-47
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17025057
[Journal Article] Neurodegeneration in heterogenous Niemann-Pick type C1 (NPC1) mouse : implication of heterogenous NPC1 mutations being a risk for tauopathy.2005
- Author(s)
  Yu W, (Yanagisawa K) et al.
- Journal Title
  
  J Biol Chem 280
  
  Pages: 27296-27302
- Data Source
  KAKENHI-PROJECT-17025057
[Journal Article] Assembly of hereditary amyloid β-protein variants in the presence of favorable gangliosides.2005
- Author(s)
  Yamamoto N, (Yanagisawa K) et al.
- Journal Title
  
  FEBS Lett 579
  
  Pages: 2185-2190
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12210022
[Journal Article] Assembly of hereditary amyloid Β-protein variants in the presence of favourable gangliosides.2005
- Author(s)
  Yamamoto N, (Yanagisawa K) et al.
- Journal Title
  
  FEBS Lett 579
  
  Pages: 2185-2190
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12210022
[Journal Article] Oligomerization of amyloid β-protein occurs during the isolation of lipid rafts.2005
- Author(s)
  Yu W, (Yanagisawa K) et al.
- Journal Title
  
  J Neurosci Res 80
  
  Pages: 114-119
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12210022
[Journal Article] Cross seeding of wild- and hereditary variant-type amyloid s-proteins in the presence of gangliosides2005
- Author(s)
  Yamamoto N, Matsuzaki K, Yanagisawa K.
- Journal Title
  
  J. Neurochem. 95
  
  Pages: 1167-1176
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17025057
[Journal Article] Altered cholesterol metabolism in Niemann-Pick Type Cl mouse brain affects mitochondria function.2005
- Author(s)
  Yu W, (Yanagisawa K) et al.
- Journal Title
  
  J Biol Chem 280
  
  Pages: 11731-11739
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12210022
[Journal Article] Murine synaptosomal lipid raft protein and lipid composition are altered by expression of humanapoE3 and 4 and by increasing age.2005
- Author(s)
  Igbavboa U, (Yanagisawa K) et al.
- Journal Title
  
  J Neurol Sci 229
  
  Pages: 225-230
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12210022
[Journal Article] Assembly of hereditary amyloid s-protein variants in the presence of favorable gangliosides2005
- Author(s)
  Yamamoto N, Hirabayashi Y, Amari M, Yamaguchi H, Romanov G, Van Nostr, W.E., Yanagisawa K.
- Journal Title
  
  FEBS Lett 579
  
  Pages: 2185-2190
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17025057
[Journal Article] Assembly of hereditary amyloid β-protein variants in the presence of favorable gangliosides.2005
- Author(s)
  Yamamoto N, (Yanagisawa K) et al.
- Journal Title
  
  FEBS Lett 579
  
  Pages: 2185-2190
- Data Source
  KAKENHI-PROJECT-17025057
[Journal Article] Accelerated AR aggregation in the presence of GM1-ganglioside-accumulated synaptosomes of aged apoE4-knock-in mouse brain.2004
- Author(s)
  Yamamoto N, (Yanagisawa K) et al.
- Journal Title
  
  FEES Lett 569
  
  Pages: 135-139
- Data Source
  KAKENHI-PROJECT-12210022
[Journal Article] PEN-2 enhances γ-cleavage after presenilin heterodimer formation.2004
- Author(s)
  Shiraishi H, (Yanagisawa K) et al.
- Journal Title
  
  J Neurochem 90
  
  Pages: 1402-1413
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12210022
[Journal Article] PEN-2 enhances g-cleavage after presenilin heterodimer formation.2004
- Author(s)
  Shiraishi H, (Yanagisawa K) et al.
- Journal Title
  
  J Neurochem 90
  
  Pages: 1402-1413
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12210022
[Journal Article] Modulation of amyloid precursor protein cleavage by cellular sphingolipid.2004
- Author(s)
  Sawamura N, (Yanagisawa K) et al.
- Journal Title
  
  J Biol Chem 279
  
  Pages: 11984-11991
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12210022
[Journal Article] Environment-and mutation-dependent aggregation behavior of Alzheimer amyloid β-protein.2004
- Author(s)
  Yamamoto N, (Yanagisawa K) et al.
- Journal Title
  
  J Neurochem 90
  
  Pages: 62-69
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12210022
[Journal Article] A seed for Alzheimer amyloid in the brain.2004
- Author(s)
  Hayashi H, (Yanagisawa K) et al.
- Journal Title
  
  J Neurosci 24
  
  Pages: 4894-4902
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12210022
[Journal Article] Modulation of amyloid precursor protein cleavage by cellular sphing olipid2004
- Author(s)
  Sawamura N, (Yanagisawa K) et al.
- Journal Title
  
  J Biol Chem 279
  
  Pages: 11984-11991
- Data Source
  KAKENHI-PROJECT-12210022
[Journal Article] Accelerated Aβ aggregation in the presence of GM1-ganglioside-accumulated synaptosomes of aged apoE4-knock-in mouse brain.2004
- Author(s)
  Yamamoto N, (Yanagisawa K) et al.
- Journal Title
  
  FEBS Lett 569
  
  Pages: 135-139
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12210022
[Journal Article] Environment- and mutation-dependent aggregation behavior of Alzheimer amyloid β-protein.2004
- Author(s)
  Yamamoto N, (Yanagisawa K) et al.
- Journal Title
  
  J Neurochem 90
  
  Pages: 62-69
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12210022
[Journal Article] The ubiquitin-like domain of Herp is involved in Herp degradation, but not necessary for its enhancement of amyloid β-protein generation.2003
- Author(s)
  Sai X, (Yanagisawa K) et al.
- Journal Title
  
  FEBS Lett 553
  
  Pages: 151-156
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12210022
[Journal Article] Amyloid β-protein (Aβ)1-40 protects neurons from damage induced by Aβ1-42 in culture and in rat brain.2003
- Author(s)
  Zou K, (Yanagisawa K) et al.
- Journal Title
  
  J Neurochem 87
  
  Pages: 609-619
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12210022
[Journal Article] Promotion of tau phosphorylation by MAP Kinase Erk1/2 Is accompanied by reduced cholesterol level in detergent-Insoluble membrane domains in Niemann-Pick C1-deficient cells.2003
- Author(s)
  Sawamura N, (Yanagisawa K) et al.
- Journal Title
  
  J Neurochem 84
  
  Pages: 1086-1096
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12210022
[Journal Article] Promotion of tau phosphorylation by MAP kinase erkl/2 is accompanied by reduced cholesterol level in detergent-insoluble membrane domains in Niemann-Pick C1-deficient cells.2003
- Author(s)
  Sawamura N, (Yanagisawa K) et al.
- Journal Title
  
  J Neurochem 84
  
  Pages: 1086-1096
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12210022
[Journal Article] A novel function of monomeric amyloid β-protein serving as an antioxidant molecule against metal-induced oxidative damage.2002
- Author(s)
  Zou K, (Yanagisawa K) et al.
- Journal Title
  
  J Neurosci 22
  
  Pages: 4833-4831
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12210022
[Journal Article] A novel function of monomeric amyloid β-protein serving as an antioxidant molecule aeainst metal-induced oxidative damage.2002
- Author(s)
  Zou K, (Yanagisawa K) et al.
- Journal Title
  
  J Neurosci 22
  
  Pages: 4833-4841
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12210022
[Journal Article] Interactions of amyloid β-protein with various gangliosides in raft like membranes : Importance of GM1 ganglioside-bound form as an endogenous seed for Alzheimer amyloid.2002
- Author(s)
  Kakio A, (Yanagisawa K) et al.
- Journal Title
  
  Biochemistry 23
  
  Pages: 7385-7390
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12210022
[Journal Article] Cholesterol is increased in the exofacial leaflet of synaptic plasma membranes of human apolipoprotein E4 knock-in mice.2002
- Author(s)
  Hayashi H, (Yanagisawa K) et al.
- Journal Title
  
  Neuroreport 13
  
  Pages: 383-386
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12210022
[Journal Article] Endoplasmic reticulum stess-inducible protein, Herp, enhances presenilin-mediated generation of amyloid β-protein.2002
- Author(s)
  Sai X, (Yanagisawa K) et al.
- Journal Title
  
  J Biol Chem 277
  
  Pages: 12915-12920
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12210022
[Journal Article] Apolipoprotein E (apoE) isoform-dependent lipid release from astrocytes prepared from human-apoE3-and apoE4-knock-in mice.2002
- Author(s)
  Gong JS, (Yanagisawa K) et al.
- Journal Title
  
  J Biol Chem 277
  
  Pages: 29919-29926
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12210022
[Journal Article] Cholesterol and pathological processes in Alzheimer's disease.2002
- Author(s)
  Yanagisawa K.
- Journal Title
  
  J Neurosci Res 70
  
  Pages: 361-366
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12210022
[Journal Article] Amyloid β-protein affects cholesterol metabolism in cultured neurons : Implications for pivotal role of cholesterol in the amyloid cascade.2002
- Author(s)
  Gong JS, (Yanagisawa K) et al.
- Journal Title
  
  J Neurosci Res 70
  
  Pages: 438-466
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12210022
[Journal Article] Cholesterol-dependent modulation of dendrite outgrowth and microtubule stability in cultured neurons.2002
- Author(s)
  Fan QW, (Yanagisawa K) et al.
- Journal Title
  
  J Neurochem 80
  
  Pages: 178-190
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12210022
[Journal Article] A new functional screening system for identification of regulators for the generation of amyloid β-protein.2002
- Author(s)
  Komano H, (Yanagisawa K) et al.
- Journal Title
  
  J Biol Chem 277
  
  Pages: 39627-39633
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12210022
[Journal Article] Apolipoprotein E (apoE) isoform-dependent lipid release from astrocytes prepared from human-apoE3- and apoE4-knock-in mice.2002
- Author(s)
  Gong JS, (Yanagisawa K) et al.
- Journal Title
  
  J Biol Chem 277
  
  Pages: 29919-29926
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12210022
[Journal Article] Cholesterol-dependent formation of GM1 ganglioside-bound amyloid β-protein, an endogenous seed for Alzheimer amyloid.2001
- Author(s)
  Kakio A, (Yanagisawa K, Matsuzaki K) et al.
- Journal Title
  
  J Biol Chem 276
  
  Pages: 24985-24990
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12210022
[Journal Article] A novel action of Alzheimer's amyloid β-protein (Aβ) : oligomeric Aβ promotes lipid release.2001
- Author(s)
  Michikawa M, (Yanagisawa K) et al.
- Journal Title
  
  J Neurosci 21
  
  Pages: 7226-7235
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12210022
[Journal Article] Cholesterol-dependent formation of GM1 ganglioside-bound amyloid β-protein an endogenous seed for Alzheimer amyloid.2001
- Author(s)
  Kakio A, (Yanagisawa K, Matsuzaki K) et al.
- Journal Title
  
  J Biol Chem 276
  
  Pages: 24985-24990
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12210022
[Journal Article] Site-specific phosphorylation of tau accompanied by activation of mitogen-activated protein kinase (MAPK) in brains of Niemann-Pick type C mice.2001
- Author(s)
  Sawamura N, (Yanagisawa K) et al.
- Journal Title
  
  J Biol Chem 276
  
  Pages: 10314-10319
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12210022
[Journal Article] Cholesterol-dependent microtubule stabilization by modulating tau phosphorylation.2001
- Author(s)
  Fan Q-W, ( Yanagisawa K ) et al.
- Journal Title
  
  J Neurochem 76
  
  Pages: 391-400
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12210022
[Journal Article] A novel action of Alzheimer's amyloid β-protein (Aβ) : oligomeric Aβ promotes lipid release.2001
- Author(s)
  Michikawa M, (Yanagisawa K) et al.
- Journal Title
  
  J Neurosci 21(18)
  
  Pages: 7226-7235
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12210022
[Journal Article] Inhibitory effect of a presenilin 1 mutation on the Wnt signalling pathway by enhancement of β-catenin phosphorylation.2001
- Author(s)
  Kawamura Y, (Yanagisawa K) et al.
- Journal Title
  
  Eur J Biochem 268
  
  Pages: 3036-3041
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12210022
[Journal Article] Cholesterol-dependent microtubule stabilization by modulating tau phosphorylation.2001
- Author(s)
  Fan Q-W, (Yanagisawa K) et al.
- Journal Title
  
  J Neurochem 76
  
  Pages: 391-400
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12210022
[Journal Article] 3-(4,5-Dimethylthiazol-2-yl)-2,5-dipenyltetrazolium bromide (MTT) causes Akt phosphorylation and morphological changes in intracellular organellae in cultured rat astrocytes.2001
- Author(s)
  Isobe I, (Yanagisawa K) et al.
- Journal Title
  
  J Neurochem 77
  
  Pages: 274-280
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12210022
[Journal Article] 3-(4,5-Dimethylthiazol-2-y1)-2,5-dipenyltetrazolium bromide (MTT) causes Akt phosphorylation and morphological changes in intracellular organellae in cultured rat astrocytes.2001
- Author(s)
  Isobe I, (Yanagisawa K) et al.
- Journal Title
  
  J Neurochem 77
  
  Pages: 274-280
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12210022
[Journal Article] Extracellular and intraneuronal HMW-Abeta Os represent a molecular basis of memory loss in Alzheimer's disease model mouse.
- Author(s)
  Takamura Y, (Yamamoto N, Yanagisawa K), et al.
- Journal Title
  
  Mol Neurodegener
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300118
[Presentation] Role of lipids in the development of Alzheimer pathology2012
- Author(s)
  Yanagisawa K.
- Organizer
  International Conference on Alzheimer's Disease.
- Place of Presentation
  Tianjin, China.
- Year and Date
  2012-09-18
- Data Source
  KAKENHI-PROJECT-22300118
[Presentation] アミロイドベータの凝集機構の解明のためのGM1含有生体膜モデルの構築2012
- Author(s)
  福田竜統, 小島昂大, 松原輝彦, 山本直樹, 柳澤勝彦, 佐藤智典
- Organizer
  日本化学会第92春季年会(2012)
- Place of Presentation
  慶應義塾大学(横浜)
- Year and Date
  2012-03-25
- Data Source
  KAKENHI-PROJECT-22300118
[Presentation] Investigating rare lysosomal storage disorders to elucidate the sphingolipidosis-proteinopathy connection in common neurodegenerative disorders2011
- Author(s)
  Wustman B.A., et al.(Yanagisawa K)
- Organizer
  Neuroscience Meeting 2011
- Place of Presentation
  Washington Convention Center. (Washington DC.USA)
- Year and Date
  2011-11-12
- Data Source
  KAKENHI-PROJECT-22300118
[Presentation] 認知症とうつ病～神経病理学の観点から～2011
- Author(s)
  柳澤勝彦
- Organizer
  日本うつ病学会緊急シンポジウム「うつ病克服へのロードマップ」
- Place of Presentation
  新宿明治安田生命ホール(東京)(招待講演)
- Year and Date
  2011-12-18
- Data Source
  KAKENHI-PROJECT-22300118
[Presentation] 治療戦略:最近の知見からみた治療開発の展望2011
- Author(s)
  柳澤勝彦
- Organizer
  第29回日本神経治療学会
- Place of Presentation
  フェニックスプラザ(福井)(招待講演)
- Year and Date
  2011-11-17
- Data Source
  KAKENHI-PROJECT-22300118
[Presentation] Ganglioside-induced conformational change of amyloid ss-protein as an initial step in the process of Alzheimer disease2011
- Author(s)
  Yanagisawa K.
- Organizer
  The 31^<st> Naito Conference on GlycanExpression and Regulation.〔II〕 : Metabolites, Stress Response, Microdomains, and Beyond
- Place of Presentation
  シャトーレーゼガトーキングダムサッポロ(北海道)(招待講演)
- Year and Date
  2011-09-15
- Data Source
  KAKENHI-PROJECT-22300118
[Presentation] GM1含有脂質膜におけるアミロイドベータの凝集機構の解析2011
- Author(s)
  小島昂大, 松原輝彦, 山本直樹, 柳澤勝彦, その他
- Organizer
  日本化学会第91春季年会
- Place of Presentation
  神奈川大学(神奈川県)
- Year and Date
  2011-03-15
- Data Source
  KAKENHI-PROJECT-22300118
[Presentation] Ganglioside-induced conformational change of amyloid ss-protein as an initial step in the process of Alzheimer disease2011
- Author(s)
  Yanagisawa K.
- Organizer
  The 31st Naito Conference on Glycan -Expression and Regulation. 〔II〕: Metabolites, Stress Response, Microdomains, and Beyond
- Place of Presentation
  シャトーレーゼガトーキングダムサッポロ,北海道
- Year and Date
  2011-09-15
- Data Source
  KAKENHI-PROJECT-22300118
[Presentation] アルツハイマー病の治療:現状と展望2011
- Author(s)
  柳澤勝彦
- Organizer
  第107回日本精神神経学会学術総会シンポジウム「認知症、これからの診断、治療-新たな抗アルツハイマー病薬の出現をへて-」
- Place of Presentation
  ホテルグランパシフィック1E DAIBA(東京都)(招待講演)
- Year and Date
  2011-10-26
- Data Source
  KAKENHI-PROJECT-22300118
[Presentation] Molecular Mechanism Underlying Initiation of Development of Alzheimer Disease and Therapeutic Strategy2011
- Author(s)
  Yanagisawa K.
- Organizer
  German Reserach and Innovation Forum. German-Japanese Symposium on Ageing and Neurodegeneration
- Place of Presentation
  ウェスティンホテル大阪(大阪府)(招待講演)
- Year and Date
  2011-12-12
- Data Source
  KAKENHI-PROJECT-22300118
[Presentation] 神経細胞endocytosis障害によるGM1ガングリオシド誘導性アミロイドss蛋白重合の促進2010
- Author(s)
  湯山耕平、柳澤勝彦
- Organizer
  第29回日本認知症学会学術集会
- Place of Presentation
  ウィンクあいち(愛知県)
- Year and Date
  2010-11-05
- Data Source
  KAKENHI-PROJECT-22300118
[Presentation] NMR法を用いたアミロイドβとガングリオシドクラスターの相互作用解析2010
- Author(s)
  矢木真穂,(柳澤勝彦)
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Year and Date
  2010-03-28
- Data Source
  KAKENHI-PROJECT-17025057
[Presentation] Pathological significance of ganglioside cluster in Alzheimer disease.2009
- Author(s)
  柳澤勝彦
- Organizer
  第51回日本脂質生化学会
- Place of Presentation
  名古屋
- Year and Date
  2009-07-30
- Data Source
  KAKENHI-PROJECT-17025057
[Presentation] NMR法によるアミロイドペプチドとGM1ガングリオシドクラスターとの相互作用解析2009
- Author(s)
  矢木-内海真穂,(柳澤勝彦)
- Organizer
  第7回「若手の力」フォーラムおよび拠点共同研究報告会
- Place of Presentation
  名古屋
- Year and Date
  2009-09-30
- Data Source
  KAKENHI-PROJECT-17025057
[Presentation] NMR analyses of interaction mode of amyloid -peptide with GM1 ganglioside clusters2009
- Author(s)
  Yagi-Utsumi M,(Yanagisawa K)
- Organizer
  3rd Asia-Pacific NMR Symposium
- Place of Presentation
  韓国チェジュ島
- Year and Date
  2009-10-26
- Data Source
  KAKENHI-PROJECT-17025057
[Presentation] アルツハイマー病におけるGM1ガングリオシド誘導性アミロイドs蛋白質重合に関与する後期エンドサイトーシス障害2009
- Author(s)
  湯山耕平, 柳澤勝彦
- Organizer
  第52回日本神経化学会大会
- Place of Presentation
  渋川
- Year and Date
  2009-06-22
- Data Source
  KAKENHI-PROJECT-17025057
[Presentation] Seed形成の細胞生物学的基礎:ガングリオシドマイクロドメインの役割2009
- Author(s)
  柳澤勝彦
- Organizer
  大阪大学蛋白質研究所セミナー「蛋白質立体構造を基盤とするプリオン現象の解明と制御」
- Place of Presentation
  吹田
- Year and Date
  2009-07-13
- Data Source
  KAKENHI-PROJECT-17025057
[Presentation] アルツハイマー病におけるGM1ガングリオシド誘導性アミロイドβ蛋白質重合に関与する後期エンドサイトーシス障害2009
- Author(s)
  湯山耕平,(柳澤勝彦)
- Organizer
  第52回日本神経化学会大会
- Place of Presentation
  渋川
- Year and Date
  2009-06-22
- Data Source
  KAKENHI-PROJECT-17025057
[Presentation] GM1ガングリオシドのエンドサイトーシス制御によるアルツハイマー病細胞モデルの構築2008
- Author(s)
  湯山耕平、(柳澤勝彦)
- Organizer
  糖鎖機能研究会
- Place of Presentation
  岡崎
- Year and Date
  2008-05-22
- Data Source
  KAKENHI-PROJECT-17025057
[Presentation] カニクイザル脳におけるアルツハイマー病関連蛋白(As、タウ)の解析2008
- Author(s)
  及川尚人, 木村展之, 柳澤勝彦
- Organizer
  第27回日本認知症学会
- Place of Presentation
  前橋
- Year and Date
  2008-10-11
- Data Source
  KAKENHI-PROJECT-17025057
[Presentation] シナプス前膜の年齢依存的なGM1 ganglioisde集積ドメイン形成はAs線維化を促す2008
- Author(s)
  山本直樹, 松原輝彦, 湯山耕平, 佐藤智典, 柳澤勝彦
- Organizer
  第51回日本神経化学会大会
- Place of Presentation
  富山
- Year and Date
  2008-09-12
- Data Source
  KAKENHI-PROJECT-17025057
[Presentation] カニクイザル脳におけるアルツハイマー病関連蛋白(Aβ、タウ)の解析2008
- Author(s)
  及川尚人、(柳澤勝彦)
- Organizer
  第27回日本認知症学会
- Place of Presentation
  前橋
- Year and Date
  2008-10-11
- Data Source
  KAKENHI-PROJECT-17025057
[Presentation] Ganglioside-induced Aβ assembly as an early event of Alzheimer's disease.2008
- Author(s)
  Yanagisawa K.
- Organizer
  10th International Hong Kong/Spreingfield Pan-Asian Symposium on Advances on Alzheimer Therapy
- Place of Presentation
  Hong Kong
- Year and Date
  2008-03-01
- Data Source
  KAKENHI-PROJECT-17025057
[Presentation] シナプス前膜の年齢依存的なGM1 ganglioside集積ドメイン形成はAβ線維化を促す2008
- Author(s)
  山本直樹、(柳澤勝彦)
- Organizer
  第51回日本神経化学会大会
- Place of Presentation
  富山
- Year and Date
  2008-09-12
- Data Source
  KAKENHI-PROJECT-17025057
[Presentation] Aβ重合開始の分子機構2008
- Author(s)
  柳澤勝彦
- Organizer
  第51回日本神経化学会大会
- Place of Presentation
  富山
- Year and Date
  2008-09-12
- Data Source
  KAKENHI-PROJECT-17025057
[Presentation] Aβ線維化に関与するGM1ガングリオシド集積を誘導するエンドサイトーシス経路障害2008
- Author(s)
  湯山耕平、(柳澤勝彦)
- Organizer
  第51回日本神経化学会大会
- Place of Presentation
  富山
- Year and Date
  2008-09-12
- Data Source
  KAKENHI-PROJECT-17025057
[Presentation] As線維化に関与するGM1ガングリオシド集積を誘導するエンドサイトーシス経路障害2008
- Author(s)
  湯山耕平, 山本直樹, 柳澤勝彦
- Organizer
  第51回日本神経化学会大会
- Place of Presentation
  富山
- Year and Date
  2008-09-21
- Data Source
  KAKENHI-PROJECT-17025057
[Presentation] アルツハイマー病 - Up date.2007
- Author(s)
  柳澤勝彦
- Organizer
  第22回日本老年精神医学会
- Place of Presentation
  大阪
- Year and Date
  2007-10-16
- Data Source
  KAKENHI-PROJECT-17025057
[Presentation] A ganglioside-induced soluble As assembly causes neuronal death through NGF receptors2007
- Author(s)
  Yamamoto N, Matsubara E, Maeda S, Minagawa H, Takashima A, Michikawa M, Yanagisawa K.
- Organizer
  37th Society for Neuroscience Annual Meeting
- Place of Presentation
  サンディエゴ, アメリカ
- Year and Date
  2007-11-05
- Data Source
  KAKENHI-PROJECT-17025057
[Presentation] アミロイドβペプチド・GM1ガングリオシド相互作用系のNMR解析2007
- Author(s)
  内海真穂、(柳澤勝彦)、その他
- Organizer
  第27回日本糖質学会年会
- Place of Presentation
  福岡
- Year and Date
  2007-08-02
- Data Source
  KAKENHI-PROJECT-17025057
[Presentation] A ganglioside-induced toxic soluble Aβ assembly.2007
- Author(s)
  柳澤勝彦
- Organizer
  第257回東北大学薬学研究科セミナー
- Place of Presentation
  仙台
- Year and Date
  2007-11-09
- Data Source
  KAKENHI-PROJECT-17025057
[Presentation] PC12細胞エンドーシス径路障害時におけるGM1ガングリオシドの細胞外放出2007
- Author(s)
  湯山耕平、(柳澤勝彦)、その他
- Organizer
  第27回日本糖質学会年会
- Place of Presentation
  福岡
- Year and Date
  2007-08-02
- Data Source
  KAKENHI-PROJECT-17025057
[Presentation] 細胞膜脂質とアルツハイマー病2007
- Author(s)
  柳澤勝彦
- Organizer
  第29回日本フリーラジカル学会・第31回日本過酸化脂質フリーラジカル学会合同大会
- Place of Presentation
  名古屋
- Year and Date
  2007-06-09
- Data Source
  KAKENHI-PROJECT-17025057
[Presentation] 老齢マウス脳シナプス膜中の特異なGM1 ganglioside集積ドメイン2007
- Author(s)
  山本直樹, 湯山耕平, 柳澤勝彦
- Organizer
  50回日本神経化学会大会
- Place of Presentation
  横浜
- Year and Date
  2007-09-10
- Data Source
  KAKENHI-PROJECT-17025057
[Presentation] Ganglioside-induced Aβ assembly in Alzheimer disease.2007
- Author(s)
  Yanagisawa K.
- Organizer
  Inangural Meeting of the Korea Society for Neuro degenerative Disorder.
- Place of Presentation
  Seoul, Korea
- Year and Date
  2007-04-14
- Data Source
  KAKENHI-PROJECT-17025057
[Presentation] 安定同位体利用NMR法によるGM1ミセル結合型アミロイドβの構造解析2007
- Author(s)
  内海真穂、(柳澤勝彦)、その他
- Organizer
  第50回日本神経化学会大会
- Place of Presentation
  横浜
- Year and Date
  2007-09-10
- Data Source
  KAKENHI-PROJECT-17025057
[Presentation] アミロイドβ蛋白の構造変化とアルツハイマー病2007
- Author(s)
  柳澤勝彦
- Organizer
  第7回日本タンパク質科学会年会
- Place of Presentation
  仙台
- Year and Date
  2007-05-25
- Data Source
  KAKENHI-PROJECT-17025057
[Presentation] アルツハイマー病の分子病理と治療戦略2007
- Author(s)
  柳澤勝彦
- Organizer
  第23回創薬セミナー
- Place of Presentation
  長野
- Year and Date
  2007-07-25
- Data Source
  KAKENHI-PROJECT-17025057
[Presentation] 脳内Aβ蓄積の時空間的特性の基盤:細胞膜脂質環境の重要性2007
- Author(s)
  柳澤勝彦
- Organizer
  第26回日本認知症学会シンポジウム
- Place of Presentation
  大阪
- Year and Date
  2007-10-17
- Data Source
  KAKENHI-PROJECT-17025057
[Presentation] エンドサイトーシス経路異常によるGM1ガングリオシドの細胞外放出の促進2007
- Author(s)
  湯山耕平, 山本直樹, 柳澤勝彦
- Organizer
  第50回日本神経化学会大会
- Place of Presentation
  横浜
- Year and Date
  2007-09-10
- Data Source
  KAKENHI-PROJECT-17025057
[Presentation] エンドサイトーシス径路異常によるGM1ガングリオシドの細胞外放出の促進2007
- Author(s)
  湯山耕平、(柳澤勝彦)、その他
- Organizer
  第50回日本神経化学会大会
- Place of Presentation
  横浜
- Year and Date
  2007-09-10
- Data Source
  KAKENHI-PROJECT-17025057
[Presentation] 老齢マウス脳シナプス膜中の特異なGM1 ganglioside 集積ドメイン2007
- Author(s)
  山本直樹、(柳澤勝彦)、その他
- Organizer
  第50回日本神経化学会大会
- Place of Presentation
  横浜
- Year and Date
  2007-09-10
- Data Source
  KAKENHI-PROJECT-17025057
[Presentation] A ganglioside-induced soluble Aβ assembly causes neuronal death through NGF receptors.2007
- Author(s)
  Yamamoto N, (Yanagisawa K) et al.
- Organizer
  37th Society for Neuroscience Annual Meeting
- Place of Presentation
  San Diego, U. S. A.
- Year and Date
  2007-11-05
- Data Source
  KAKENHI-PROJECT-17025057
[Presentation] アルツハイマー病発祥と神経細胞膜脂質2007
- Author(s)
  柳澤勝彦
- Organizer
  第16回日本脂質栄養学会シンポジウム
- Place of Presentation
  島根
- Year and Date
  2007-08-31
- Data Source
  KAKENHI-PROJECT-17025057
[Presentation] A ganglioside-induced toxic soluble As assemblycauses neuronal death2006
- Author(s)
  山本直樹, 松原悦朗, 前田純裕, 高島明彦, 丸山和佳子, 道川誠, 柳澤勝彦
- Organizer
  第29回日本分子生物学会年会
- Place of Presentation
  名古屋
- Year and Date
  2006-12-06
- Data Source
  KAKENHI-PROJECT-17025057
[Presentation] GM1 ganglioside accumulation in PC12 cells treated with chloroquine: a cellular model of As assembly2006
- Author(s)
  湯山耕平, 山本直樹, 柳澤勝彦
- Organizer
  第49回日本神経化学大会
- Place of Presentation
  名古屋
- Year and Date
  2006-09-14
- Data Source
  KAKENHI-PROJECT-17025057
[Presentation] GM1-ganglioside-induced As assembly at neuritic terminals of nerve growth factor-treated PC12 cells2006
- Author(s)
  山本直樹, 湯山耕平, 柳澤勝彦
- Organizer
  第49回日本神経化学大会
- Place of Presentation
  名古屋
- Year and Date
  2006-09-14
- Data Source
  KAKENHI-PROJECT-17025057
[Presentation] アミロイドs蛋白重合とガングリオシド2005
- Author(s)
  柳澤勝彦
- Organizer
  第28回日本神経科学大会シンポジウム「糖鎖科学と神経科学の融合による新展開」
- Place of Presentation
  横浜
- Year and Date
  2005-07-27
- Data Source
  KAKENHI-PROJECT-17025057
[Presentation] Pivotal roles of lipids in generating an endogenous seed for Alzheimer amyloid2005
- Author(s)
  Yanagisawa K.
- Organizer
  7th International Conference on Alzheimer's Disease and Parkinson Disease. Sorrento
- Place of Presentation
  イタリア
- Data Source
  KAKENHI-PROJECT-17025057
[Presentation] 膜マイクロドメインとアルツハイマー病:GM1ガングリオシド集積の意味2005
- Author(s)
  柳澤勝彦
- Organizer
  第28回日本分子生物学会
- Place of Presentation
  福岡
- Year and Date
  2005-12-10
- Data Source
  KAKENHI-PROJECT-17025057
[Presentation] Assembly of hereditary variant amyloid s-protein in the presence of gangliosides2005
- Author(s)
  Yamamoto N, Hirabayashi Y, Amari M, Yamaguchi H, Romanov G, Nostr, W, Yanagisawa K.
- Organizer
  第48回日本神経化学会
- Place of Presentation
  福岡
- Year and Date
  2005-09-28
- Data Source
  KAKENHI-PROJECT-17025057
[Presentation] Role of lipids in the development of Alzheimer pathology.
- Author(s)
  Yanagisawa K.
- Organizer
  International Conference on Alzheimer’s Disease.
- Place of Presentation
  Tianjin, China.
- Invited
- Data Source
  KAKENHI-PROJECT-22300118
[Presentation] Pathological significance of ganglioside cluster in Alzheimer disesse
- Author(s)
  柳澤勝彦
- Data Source
  KAKENHI-PROJECT-17025057

1. IHARA Yasuo (60114386)

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2. KATO Koichi (20211849)

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3. MURAYAMA Shigeo (50183653)

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4. MATSUBARA Teruhiko (10325251)

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5. YAMAMOTO Naoki (90393157)

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6. MIYATAKE Tadashi (50048998)

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7. UCHIHARA Toshiki (10223570)

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8. R.C.PARK MATSUMOTO (60165917)

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9. IWATSUBO Takeshi (50223409)

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10. YAMAZAKI Tsuneo (80200658)

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11. MORISHIMA Maho (50204722)

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12. YAMAGUCHI Haruyasu (00158114)

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13. SASAKI Atsushi (80225862)

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14. 辻省次 (70150612)

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15. 松崎勝巳 (00201773)

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16. 浦上克哉 (30213507)

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17. C.FUJITA Shinobu

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18. KAWARABAYASHI Takeshi

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# of Collaborated Products: 1 results
19. 松崎勝己

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
20. 佐藤智典

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 東海林幹夫

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# of Collaborated Products: 1 results
22. 松原悦朗

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 田口良

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yanagisawa Katsuhiko 柳澤 勝彦

YANAGISAWA Katsuhiko 柳澤 勝彦

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Study on molecular mechanism underlying brain region-specific Ass depositionPrincipal Investigator

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Molecular mechanism underlying Ass assembly in Alzheimer brain : pathological and therapeutic significance of an endogenous seed for amyloidPrincipal Investigator

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Influence of membrane lipid metabolism on cerebral amyloid deposition and neurodegeneration.

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An investigation into molecular mechanism underlying Aβ assemblyPrincipal Investigator

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アルツハイマー病脳におけるアミロイドβ蛋白蓄積の初期機構に関する生化学的研究Principal Investigator

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Studies on beta-amyloidogenesis-isolation of membrane-bound Abeta

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POSITIONAL CLONING OF CANDIDATE GENES

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[Book] Amyloid, arises on the membranes and acts on the membranes. In : Amyloids: Composition, Function and Pathology2012

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[Book] Amyloid, arises on the membranes and acts on the membranes. In:Amyloids: Composition, Function and Pathology (edited by Irene P. Halcheck and Nancy R. Vernon)2012

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[Book] Research Progress in Alzheimer's Disease(edited by Miao-Kun Sun, Pivotal roles of cholesterol and gangliosides in aggregation of amyloid β-protein.)2010

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[Book] Comprehensive Glycoscience(edited by Kamerling J.P., Boons G-J., Lee Y.C.,Suzuki A. and Taniguchi N., Glycoconjugates and neurological diseases.)2007

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[Book] Comprehensive Glycoscience2007

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[Book] Ganglioside and Alzheimer's Disease. In: Sphingolipid Biology2006

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[Book] Sphingolipid Biology.(edited by Hirabayashi Y, Igarashi Y and Merill AH, Ganglioside and Alzheimer's disease.)2006

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[Book] Pivotal roles of cholesterol and gangliosides in aggregation of amyloid β-protein. Research Progress in Alzheimer's Disease Interactions.2005

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Yanagisawa Katsuhiko 柳澤勝彦

YANAGISAWA Katsuhiko 柳澤勝彦