Takahashi Yoshitaka 高橋吉孝

… Alternative Names

TAKAHASHI Yoshitaka 高橋吉孝

TAKAHASHI Yashitaka 高橋吉孝

高橋吉孝タカハシヨシタカ

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Researcher Number	10236333
Other IDs
External Links
Affiliation (Current)	2025: 岡山県立大学, 保健福祉学部, 教授
Affiliation (based on the past Project Information) *help	2008 – 2023: Okayama Prefectural University, 保健福祉学部, 教授 2009: 岡山県立大学, 保険福祉学部, 教授 2003: KANAZAWA UNIVERSITY, Graduate School of Medical Science, Lecturer, 大学院・医学系研究科, 講師 2001 – 2003: 金沢大学, 大学院・医学系研究科, 助手 2000: 金沢大学, 医学部, 助手 1997 – 1998: 金沢大学, 医学部, 助手 1991 – 1993: Department of Biochemistry, Tokushima University, School of Medicine, Instructor, 医学部, 助手
Review Section/Research Field	Principal Investigator Basic Section 59040:Nutrition science and health science-related / Applied pharmacology / General medical chemistry / Eating habits, studies on eating habits / Functional biochemistry Except Principal Investigator General medical chemistry / Food science / Basic Section 59040:Nutrition science and health science-related / Laboratory medicine
Keywords	Principal Investigator 肝星細胞 / 12 / 12-リポキシゲナーゼ / アラキドン酸 / 血小板型12-リポキシゲナーゼ / リポキシゲナーゼ / 肝臓 / 15-リポキシゲナーゼ / 酸化LDL / NASH … More / 食品 / 薬理学 / 非アルコール性脂肪性肝炎 / Cholesteryl ester / LDL-receptor-related protein / Oxidized LDL / Macrophage / 15-Lipoxygenase / トランスロケーション / 15-リポシゲナーゼ / コレステロールエステル / LDL受容体関連蛋白 / マクロファージ / 単鎖抗体 / ロイコトリエン / ケルセチン / グアバ茶 / 12/15-リポキシゲナーゼ / グアバ葉 / グアバポリフェノール / 動脈硬化 / overexpression / matrix metalloproteinase / TPA / ヒト乳癌細胞株 / プロスタグランジン / シクロオキシゲナーゼ … More Except Principal Investigator リポキシゲナーゼ / Lipoxygenase / アラキドン酸 / 受容体 / Prostaglandin / Arachidonic acid / Cyclooxygenase / 骨芽細胞 / cDNA / プロスタグランジン / マクロファージ / 食品 / 酵素活性 / 加熱処理 / Translocation / Cholesterol ester / LDL receptor-related protein / Oxidized LDL / Macrophage / スカベンジャー受容体 / 15-リポキシゲナーゼ / 12 / トランスロケーション / コレステロールエステル / LDL受容体関連蛋白 / 酸化LDL / Leukocyte / Osteoblast / Signal transduction / Enzyme induction / 遺伝子発現 / 不飽和脂肪酸 / 酸素添加酵素 / 白血球 / シグナル伝達 / 酵素誘導 / シクロオキシゲナーゼ / Enzyme immunoassay / Monoclonal antibody / Leukotriene / 生理活性物質 / 11ーデヒドロートロンボキサン / 酵素免疫測定法 / モノクロ-ン抗体 / ロイコトリエン / シクロオキシゲナ-ゼ / リポキシゲナ-ゼ / COXII / RPS2 / NOS阻害剤 / 老化 / 内因性NOS阻害剤 / タンパク質の翻訳後修飾 / 非対称性ジメチルアルギニン / 一酸化窒素 / DDAH / PRMT / ADMA / 中枢神経系 / アルギニンメチル化タンパク質 / 翻訳後修飾 / ミオグロビン / GLUT4 / 筋管細胞 / TNF-α / IL-6 / 3T3-L1細胞 / 内臓脂肪細胞 / eNOS / 血管内皮細胞 / AMPK / 肥満 / 脂肪代謝 / 細胞・組織 / 酢酸 / 脂質代謝 / メタボリックシンドローム / 神経保護因子 / FOX / ドコサヘキサエン酸 / n-3系脂肪酸 Less

NASHの肝線維化過程における血小板型12－リポキシゲナーゼの役割の解明Principal Investigator
- Principal Investigator
  
  高橋吉孝
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Okayama Prefectural University
Does platelet-type 12-lipoxygenase play any role in the development of fibrosis in NASH?Principal Investigator
- Principal Investigator
  
  Takahashi Yoshitaka
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Okayama Prefectural University
Study on effect of changes in food ingredients on the catalytic activities of arachidonic acid-metabolizing enzymes
- Principal Investigator
  
  Kawakami Yuki
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Okayama Prefectural University
Study aiming for the development of NASH prevention focusing on lipoxygenasePrincipal Investigator
- Principal Investigator
  
  Takahashi Yoshitaka
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Okayama Prefectural University
Study on anti-leukotriene single-chain antibody aiming to develop medicines for chronic inflammatory diseasesPrincipal Investigator
- Principal Investigator
  
  Takahashi Yoshitaka
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Okayama Prefectural University
Searching for neurodegenerative disease-related factors in the metabolic systems of ADMA-containing protein and the elucidation of the functional mechanism
- Principal Investigator
  
  KIMOTO Masumi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Okayama Prefectural University
Studies on the protective effect of acetate on metabolic syndrome
- Principal Investigator
  
  YAMASHITA Hiromi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Food science
- Research Institution
  Okayama Prefectural University
Study for the development of a novel treatment to prevent atherosclerosis with guava teaPrincipal Investigator
- Principal Investigator
  
  TAKAHASHI Yoshitaka
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Eating habits, studies on eating habits
- Research Institution
  Okayama Prefectural University
Metabolism of n-3 polyunsaturated fatty acids by lipoxygenases and production of novel bioactive agents
- Principal Investigator
  
  JISAKA Mitsuo
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Food science
- Research Institution
  Shimane University
Investigation of the functional molecules and mechanism on the LDL oxidation causing atherosclerosis -essential roles of 12/15-lipoxygenase-Principal Investigator
- Principal Investigator
  
  TAKAHASHI Yoshitaka
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  KANAZAWA UNIVERSITY
Pathophysiological role of lipid molecules produced by 12/l5-lipoxygenase
- Principal Investigator
  
  YOSHIMOTO Tanihiro
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Kanazawa University
ヒト乳癌細胞の増殖ならびに浸潤転移におけるエイコサノイドの役割Principal Investigator
- Principal Investigator
  
  高橋吉孝
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Functional biochemistry
- Research Institution
  Kanazawa University
Molecular biological studies on cyclooxygenases and lipoxygenases dynamics
- Principal Investigator
  
  YAMAMOTO Shozo
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Tokushima University School of Medicine
Study on the physiological and pathological dynamics of cyclooxygenase and lipoxygenase enzymes
- Principal Investigator
  
  YAMAMOTO Shozo
- Project Period (FY)
  1989 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  General medical chemistry
- Research Institution
  The University of Tokushima

[Book] エイコサノイドと関連化合物 (1)生合成と生理作用 (中野・ほか編,ビタミン総合辞典2010
- Author(s)
  高橋吉孝
- Publisher
  朝倉書店
- Data Source
  KAKENHI-PROJECT-20500713
[Book] 栄養科学シリーズNEXT 「基礎有機化学」2010
- Author(s)
  高橋吉孝・辻英明編
- Total Pages
  148
- Publisher
  講談社サイエンティフィク
- Data Source
  KAKENHI-PROJECT-20500713
[Journal Article] Lipid profiling reveals the presence of unique lipid mediators in human milk from healthy and mastitic subjects2022
- Author(s)
  Nagasaki Yuki、Kawai Erika、Maruoka Saya、Osumi Miho、Tsukayama Izumi、Kawakami Yuki、Takahashi Yoshitaka、Okazaki Yuka、Miki Yoshimi、Taketomi Yoshitaka、Yamamoto Kei、Murakami Makoto、Suzuki-Yamamoto Toshiko
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 630 Pages: 84-91
- DOI
  10.1016/j.bbrc.2022.09.051
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K11515, KAKENHI-PROJECT-22K06577, KAKENHI-PROJECT-21K19664, KAKENHI-PROJECT-22K17833, KAKENHI-PROJECT-21J15268, KAKENHI-PROJECT-19K07042, KAKENHI-PROJECT-23K22225, KAKENHI-PROJECT-20H05691
[Journal Article] Malabaricone C derived from nutmeg inhibits arachidonate 5-lipoxygenase activity and ameliorates psoriasis-like skin inflammation in mice2022
- Author(s)
  Tsukayama Izumi、Kawakami Yuki、Tamenobu Asako、Toda Keisuke、Maruoka Saya、Nagasaki Yuki、Mori Yoshiko、Sawazumi Risa、Okamoto Kensuke、Kanzaki Keita、Ito Hideyuki、Takahashi Yoshitaka、Miki Yoshimi、Yamamoto Kei、Murakami Makoto、Suzuki-Yamamoto Toshiko
- Journal Title
  
  Free Radical Biology and Medicine
  
  Volume: 193 Pages: 1-8
- DOI
  10.1016/j.freeradbiomed.2022.09.028
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K11515, KAKENHI-PROJECT-22K06577, KAKENHI-PROJECT-21K19664, KAKENHI-PROJECT-21K17641, KAKENHI-PROJECT-22K17833, KAKENHI-PROJECT-21J15268, KAKENHI-PROJECT-19K07042, KAKENHI-PROJECT-23K22225, KAKENHI-PROJECT-20H05691
[Journal Article] ALOX12 mutation in a family with dominantly inherited bleeding diathesis2021
- Author(s)
  Mitsui Tetsuo、Makino Satoshi、Tamiya Gen、Sato Hiroko、Kawakami Yuki、Takahashi Yoshitaka、Meguro Toru、Izumino Hiroko、Sudo Yosuke、Norota Ikuo、Ishii Kuniaki、Hayasaka Kiyoshi
- Journal Title
  
  Journal of Human Genetics
  
  Volume: 66 Issue: 8 Pages: 753-759
- DOI
  10.1038/s10038-020-00887-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K11515
[Journal Article] Diosgenin suppresses COX-2 and mPGES-1 via GR and improves LPS-induced liver injury in mouse.2021
- Author(s)
  Izumi Tsukayama, Takuto Mega, Nana Hojo, Keisuke Toda, Yuki Kawakami, Yoshitaka Takahashi, Toshiko Suzuki-Yamamoto.
- Journal Title
  
  Prostaglandins and Other Lipid Mediators.
  
  Volume: 156 Pages: 106580-106580
- DOI
  10.1016/j.prostaglandins.2021.106580
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K20188, KAKENHI-PROJECT-20K23293, KAKENHI-PROJECT-20K11515, KAKENHI-PROJECT-21K19664, KAKENHI-PROJECT-21K17641
[Journal Article] Red-kerneled rice proanthocyanidin inhibits arachidonate 5-lipoxygenase and decreases psoriasis-like skin inflammation2020
- Author(s)
  Toda Keisuke、Tsukayama Izumi、Nagasaki Yuki、Konoike Yuka、Tamenobu Asako、Ganeko Natsuki、Ito Hideyuki、Kawakami Yuki、Takahashi Yoshitaka、Miki Yoshimi、Yamamoto Kei、Murakami Makoto、Suzuki-Yamamoto Toshiko
- Journal Title
  
  Archives of Biochemistry and Biophysics
  
  Volume: - Pages: 108307-108307
- DOI
  10.1016/j.abb.2020.108307
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K11134, KAKENHI-PROJECT-19K07042, KAKENHI-PROJECT-19K20188, KAKENHI-PROJECT-16K08916, KAKENHI-PROJECT-20K11515, KAKENHI-PROJECT-16H02613, KAKENHI-PUBLICLY-20H04939, KAKENHI-PROJECT-19H03372
[Journal Article] Arachidonate 12S-lipoxygenase of platelet-type in hepatic stellate cells of methionine and choline-deficient diet-fed mice2020
- Author(s)
  Mori Yoshiko、Kawakami Yuki、Kanzaki Keita、Otsuki Akemi、Kimura Yuka、Kanji Hibiki、Tanaka Ryoma、Tsukayama Izumi、Hojo Nana、Suzuki-Yamamoto Toshiko、Kawakami Takayo、Takahashi Yoshitaka
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: - Issue: 5 Pages: 455-463
- DOI
  10.1093/jb/mvaa062
- NAID
  40022409777
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08916, KAKENHI-PROJECT-20K11515, KAKENHI-PROJECT-18K11134
[Journal Article] Ellagitannins from Punica granatum leaves suppress microsomal prostaglandin E synthase-1 expression and induce lung cancer cells to undergo apoptosis.2020
- Author(s)
  Keisuke Toda, Mai Ueyama, Shomu Tanaka, Izumi Tsukayama, Takuto Mega, Yuka Konoike, Asako Tamenobu, Februadi Bastian, Iria Akai, Hideyuki Ito, Yuki Kawakami, Yoshitaka Takahashi, Toshiko Suzuki-Yamamoto.
- Journal Title
  
  Bioscience, Biotechnology, and Biochemistry.
  
  Volume: 84 Issue: 4 Pages: 757-763
- DOI
  10.1080/09168451.2019.1706442
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K20188, KAKENHI-PROJECT-16K08916, KAKENHI-PROJECT-20K11515, KAKENHI-PROJECT-18K11134
[Journal Article] Involvement of the Hydroperoxy Group in the Irreversible Inhibition of Leukocyte-Type 12-Lipoxygenase by Monoterpene Glycosides Contained in the Qing Shan Lu Shui Tea2019
- Author(s)
  Kawakami Yuki、Otsuki Akemi、Mori Yoshiko、Kanzaki Keita、Suzuki-Yamamoto Toshiko、Fang Ding、Ito Hideyuki、Takahashi Yoshitaka
- Journal Title
  
  Molecules
  
  Volume: 24 Issue: 2 Pages: 304-304
- DOI
  10.3390/molecules24020304
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08916, KAKENHI-PROJECT-18K11134
[Journal Article] Ingestion of soy protein isolate attenuates eccentric contraction-induced force depression and muscle proteolysis via inhibition of calpain-1 activation in rat fast-twitch skeletal muscle2019
- Author(s)
  Kanzaki Keita、Watanabe Daiki、Aibara Chihiro、Kawakami Yuki、Yamada Takashi、Takahashi Yoshitaka、Wada Masanobu
- Journal Title
  
  Nutrition
  
  Volume: 58 Pages: 23-29
- DOI
  10.1016/j.nut.2018.06.025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08916, KAKENHI-PROJECT-17H02123
[Journal Article] Preventive effect of Dioscorea japonica on squamous cell carcinoma of mouse skin involving down-regulation of prostaglandin E2 synthetic pathway2018
- Author(s)
 Tsukayama I, Toda K, Takeda Y, Mega T, Tanaka M, Kawakami Y, Takahashi Y, Kimoto M, Yamamoto K, Miki Y, Murakami M, Suzuki-Yamamoto T.
- Journal Title
 
 Journal of Clinical Biochemistry and Nutrition
 
 Volume: 62 Issue: 2 Pages: 139-147
- DOI
 10.3164/jcbn.17-54
- NAID
 130006407477
- ISSN
 0912-0009, 1880-5086
- Language
 English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
 KAKENHI-PROJECT-16K08916, KAKENHI-PROJECT-16K18882, KAKENHI-PUBLICLY-16H01372, KAKENHI-PROJECT-15K00792, KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05905, KAKENHI-PROJECT-16H02613
[Journal Article] l-arginine ingestion inhibits eccentric contraction-induced proteolysis and force deficit via S-nitrosylation of calpain2018
- Author(s)
  Kanzaki Keita、Watanabe Daiki、Aibara Chihiro、Kawakami Yuki、Yamada Takashi、Takahashi Yoshitaka、Wada Masanobu
- Journal Title
  
  Physiological Reports
  
  Volume: 6 Issue: 2 Pages: e13582-e13582
- DOI
  10.14814/phy2.13582
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08916, KAKENHI-PROJECT-16J01194, KAKENHI-PROJECT-17H02123
[Journal Article] Molecular Cloning of Rat acss3 and Characterization of Mammalian Propionyl-CoA Synthetase in the Liver Mitochondrial Matrix2017
- Author(s)
  Y. Yoshimura, A. Araki, H. Maruta, Y. Takahashi, and H. Yamashita
- Journal Title
  
  Journal of Bochemistry
  
  Volume: 161 Pages: 279-289
- DOI
  10.1093/jb/mvw067
- NAID
  40021162084
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26850087, KAKENHI-PROJECT-15K07437, KAKENHI-PROJECT-16K08916
[Journal Article] Insulin secretory defect and insulin resistance in isolated impaired fasting glucose and isolated impaired glucose tolerance2016
- Author(s)
  Sasabe S.A., Fukushima, M, Xin X, Taniguchi A, Nakai Y, Mitsui R, Takahashi Y, Tsuji H, Yabe D, Yasuda K, Kurose, T, Inagaki N, Seino Y
- Journal Title
  
  J Diabetes Res
  
  Volume: 2016 Pages: 1298601-1298601
- DOI
  10.1155/2016/1298601
- NAID
  120005745643
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24229007, KAKENHI-PROJECT-25460657
[Journal Article] Activation of AMP-Activated Protein Kinase and Stimulation of Energy Metabolism by Acetic Acid in L6 Myotube Cells.2016
- Author(s)
  H. Maruta, Y. Yoshimura, A. Araki, M. Kimoto, Y. Takahashi, and H. Yamashita
- Journal Title
  
  PLos One
  
  Volume: 11 Issue: 6 Pages: 1-19
- DOI
  10.1371/journal.pone.0158055
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26850087, KAKENHI-PROJECT-15K07437, KAKENHI-PROJECT-16K08916
[Journal Article] The Y54(L)W mutation of anti-leukotriene C4 single-chain antibody increases affinity to leukotriene E42016
- Author(s)
  Yuki Kawakami, Mai Kinoshita, Yoshiko Mori, Shuji Okochi, Shiori Hirano, Ichika Shimoda, Keita Kanzaki, Toshiko Suzuki-Yamamoto, Masumi Kimoto, Mitsuaki Sugahara, Tetsuya Hori, Hiromichi Saino, Masashi Miyano, Shozo Yamamoto, Yoshitaka Takahashi.
- Journal Title
  
  J. Biochem.
  
  Volume: 161 Issue: 1 Pages: 79-86
- DOI
  10.1093/jb/mvw055
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K00792, KAKENHI-PROJECT-16K08916
[Journal Article] Inhibition of leukocyte-type 12-lipoxygenase by guava tea leaves prevents development of atherosclerosis.2015
- Author(s)
  Takahashi Y, Otsuki A, Mori Y, Kawakami Y, Ito H.
- Journal Title
  
  Food Chem.
  
  Volume: in press Pages: 2-5
- DOI
  10.1016/j.foodchem.2015.03.105
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460657
[Journal Article] Neutralization of leukotriene C4 and D4 activity by monoclonal and single-chain antibodies.2014
- Author(s)
  Kawakami Y, Hirano S, Kinoshita M, Otsuki A, Suzuki-Yamamoto T; Suzuki M, Kimoto M, Sasabe S, Fukushima M, Kishimoto K, Izumi T, Oga T, Narumiya S, Sugahara M, Miyano M, Yamamoto S, Takahashi Y.
- Journal Title
  
  Biochim Biophys Acta.
  
  Volume: 1840 Issue: 6 Pages: 1625-1633
- DOI
  10.1016/j.bbagen.2013.12.016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24500948, KAKENHI-PROJECT-25460657
[Journal Article] Dioscorea japonica extract down-regulates prostaglandin E2 synthetic pathway and induces apoptosis in lung cancer cells2014
- Author(s)
 Suzuki-Yamamoto T, Tanaka S, Tsukayama I, Takafuji M, Hanada T, Arakawa T, Kawakami Y, Kimoto M, Takahashi Y.
- Journal Title
 
 Journal of Clinical Biochemistry and Nutrition
 
 Volume: 55 Issue: 3 Pages: 162-167
- DOI
 10.3164/jcbn.14-25
- NAID
 130004687668
- ISSN
 0912-0009, 1880-5086
- Language
 English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
 KAKENHI-PROJECT-24500948, KAKENHI-PROJECT-25460657, KAKENHI-PROJECT-26460683
[Journal Article] Two New Monoterpene Glycosides with Inhibitory Effects on Leukocyte-type 12-Lipoxygenase Activity from Qing Shan Lu Shui Tea2013
- Author(s)
  Hideyuki Ito, Akemi Otsuki, Hitomi Mori, Peng Li, Mai Kinoshita, Yuki Kawakami, Hideaki Tsuji, Ding Zhi Fang, Yoshitaka Takahashi
- Journal Title
  
  Molecules
  
  Volume: 18 Issue: 4 Pages: 4257-4266
- DOI
  10.3390/molecules18044257
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23700916, KAKENHI-PROJECT-25460657
[Journal Article] Nuetralization of leukotriene C4 and D4 activity by monoclonal and single-chain antibodies.2013
- Author(s)
  Kawakami Y, Hirano S, Kinoshita M, Otsuki A, Suzuki-Yamamoto T, Suzuki M, Kimoto M, Sasabe S, Fukushima M, Kishimoto K, Izumi T, Oga T, Narumiya S, Sugahara M, Miyano M, Yamamoto S, Takahashi Y.
- Journal Title
  
  Biochim. Biophys. Acta
  
  Volume: 1840 Pages: 1625-1633
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590683
[Journal Article] Development of an enzyme-linked immunosorbent assay system for the determination of asymmetric dimethylarginine using a specific monoclonal antibody.2012
- Author(s)
  Yokoro M, Suzuki M, Yatani M, Yamashita H, Takahashi Y, Tsuji H, and Kimoto M.
- Journal Title
  
  Biosci. Biotechnol. Biochem.
  
  Volume: 76 Issue: 2 Pages: 400-403
- NAID
  10030400354
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590683
[Journal Article] Asymmetric dimethylarginine, an endogenous NOS inhibitor, is actively metabolized in rat erythrocytes.2012
- Author(s)
  Yokoro M, Suzuki M, Murota K, Otsuka C, Yamashita H, Takahashi Y, Tsuji H, and Kimoto M.
- Journal Title
  
  Biosci. Biotechnol. Biochem.
  
  Volume: 76 Issue: 7 Pages: 1334-1342
- NAID
  10030982013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590683
[Journal Article] Gastrointestinal Digestion and Absorption of Pen j 1, a Major Allergen from Kuruma Prawn, Penaeus japonicas.2011
- Author(s)
  Kunimoto A, Yokoro M, Murota K, Yamanishi R, Suzuki-Yamamoto T, Suzuki M, Yutani C, Doi S, Hiemori M, Yamashita H, Takahashi Y, Tsuji H, Kimoto M.
- Journal Title
  
  Biosci. Biotechnol. Biochem in press
- Data Source
  KAKENHI-PROJECT-20500713
[Journal Article] Gastrointestinal digestion and absorption of Pen j 1, a major allergen from kuruma prawn, Penaeus japonicus.2011
- Author(s)
  Kunimoto A, Yokoro M, Murota K, Yamanishi R, Suzuki-Yamamoto T, Suzuki M, Yutani C, Doi S, Hiemori M, Yamashita H, Takahashi Y, Tsuji H, and Kimoto M.
- Journal Title
  
  Biosci. Biotechnol. Biochem.
  
  Volume: 75 Issue: 7 Pages: 1249-1258
- NAID
  10029328852
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590683
[Journal Article] Functional expression of single-chain antibody to leukotriene C(4)2010
- Author(s)
  Kawakami Y, Yamashita C, Kashiwase Y, Morinaka T, Suzuki-Yamamoto T, Yamashita H, Kimoto M, Tsuji H, Kurahashi Y, Daiyasu H, Toh H, Sugahara M, Miyano M, Yamamoto S, Takahashi Y.
- Journal Title
  
  Biochem Biophys Res Commun 392
  
  Pages: 421-425
- Data Source
  KAKENHI-PROJECT-20500713
[Journal Article] Effects of acetate on lipid metabolism in muscle and adipose tissue of type 2 diabetic Otsuka Long-Evans Tokushima Fatty(OLETF) rats2009
- Author(s)
  Yamashita, H., Maruta, H., Jozuka, M., Kimura, R., Iwabuchi, H., Yamato, M., Saito, T., Fujisawa, K., Takahashi, Y., Kimoto, M., Hiemori, M., Tsuji, H.
- Journal Title
  
  Biosci. Biotechnol. Biochem
  
  Volume: 73(3) Pages: 570-576
- NAID
  10027538406
- Data Source
  KAKENHI-PROJECT-21580150
[Journal Article] Tumor-Suppressive Lipoxygenase Inhibit the Expression of c-myc mRNA Coding Region Determinant-Binding Protein/Insulin-Like 5 Growth Factor II mRNA-Binding Protein 1 in Human Prostate Carcinoma PC-3 Cells.2009
- Author(s)
  Y. Kawakami, N. Kubota, N. Ekuni, T. Suzuki-Yamamoto, M. Kimoto, H. Yamashita, H. Tsuji, T. Yoshimoto, M. Jisaka, J. Tanaka, H.F. Fujimura, Y. Miwa, Y. Takahashi
- Journal Title
  
  Bioscience, Biotechnology, and Biochemistry 73
  
  Pages: 1811-1817
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19580138
[Journal Article] Preparation and epitope mapping of a monoclonal antibody against Tri a Bd 27K, a wheat major allergen.2009
- Author(s)
  Nobuko Komiyama, Miki Hiemori, Masumi Kimoto, Makiko Suzuki, Hiromi Yamashita, Yoshitaka Takahashi, Hideaki Tsuji
- Journal Title
  
  Biosci. Biotechnol. Biochem 73
  
  Pages: 2113-2116
- Data Source
  KAKENHI-PROJECT-20500713
[Journal Article] Antiproliferative activity of guava leaf extract via inhibition of prostaglandin endoperoxide H synthase isoforms.Prostaglandins2009
- Author(s)
  Kawakami Y, Nakamura T, Hosokawa T, Suzuki-Yamamoto T, Yamashita H, Kimoto M, Tsuji H, Yoshida H, Hada H, Takahashi Y.
- Journal Title
  
  Leukotrienes and Essential Fatty Acids 80
  
  Pages: 239-245
- Data Source
  KAKENHI-PROJECT-20500713
[Journal Article] Tumor-suppressive lipoxygenases inhibit the expression of c-myc mRNA coding region determinant-binding protein/insulin-like growth factor II mRNA-binding protein 1 in human prostate carcinoma PC-3 cells.2009
- Author(s)
  Kawakami Y, Kubota N, Ekuni N, Suzuki-Yamamoto T, Kimoto M, Yamashita H, Tsuji H, Yoshimoto T, Jisaka M, Tanaka J, Fujimura HF, Miwa Y, Takahashi Y.
- Journal Title
  
  Biosci. Biotechnol. Biochem 73
  
  Pages: 1811-1817
- NAID
  10027544597
- Data Source
  KAKENHI-PROJECT-20500713
[Journal Article] Effects of acetate on lipid metabolism in muscles and adipose tissues of type 2 diabetic Otsuka Long-Evans Tokushima Fatty (OLETF) rats2009
- Author(s)
  Yamashita H, Maruta H, Jozuka M, Kimura R, Iwabuchi H, Yamato M, Saito T, Fujisawa K, Takahashi Y, Kimoto M, Hiemori M, Tsuji H.
- Journal Title
  
  Biosci Biotechnol Biochem 73
  
  Pages: 570-576
- NAID
  10027538406
- Data Source
  KAKENHI-PROJECT-20500713
[Journal Article] 動脈硬化を予防するグアバ茶の開発に向けた基礎的研究2008
- Author(s)
  高橋吉孝
- Journal Title
  
  平成19年度特別研究報告書
  
  Pages: 39-44
- Data Source
  KAKENHI-PROJECT-20500713
[Presentation] 血小板型12S-リポキシゲナーゼの肝線維化に及ぼす影響2023
- Author(s)
  戸田圭祐、岡本知子、津嘉山泉、川上祐生、山本登志子、高橋吉孝
- Organizer
  第14回川崎医科大学学術集会（岡山）
- Data Source
  KAKENHI-PROJECT-20K11515
[Presentation] 血小板型12S-リポキシゲナーゼの肝線維化に及ぼす影響2023
- Author(s)
  戸田圭祐、岡本知子、津嘉山泉、川上祐生、山本登志子、高橋吉孝
- Organizer
  第14回川崎医科大学学術集会（岡山）
- Data Source
  KAKENHI-PROJECT-23K10921
[Presentation] ナツメグ含有成分malabaricone Cによる5-リポキシゲナーゼ活性阻害と気管支喘息改善効果2023
- Author(s)
  川上祐生、津嘉山泉、戸田圭祐、伊東秀之、高橋吉孝、山本登志子
- Organizer
  第96回日本生化学会大会（福岡）
- Data Source
  KAKENHI-PROJECT-23K10921
[Presentation] Malabaricone C derived from nutmeg inhibits arachidonate 5-lipoxygenase activity ameliorating murine psoriasis-like skin inflammation and OVA-induced allergic airway inflammation2023
- Author(s)
  Toshiko Suzuki-Yamamoto, Izumi Tsukayama, Yuki Kawakami, Asako Tamenobu, Keisuke Toda, Saya Maruoka, Hideyuki Ito, Yoshitaka Takahashi, Yoshimi Miki, Makoto Murakami
- Organizer
  ICBL 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K10921
[Presentation] チェリー・オブ・ザ・リオ・グランデ葉に含まれる5-リポキシゲナーゼ阻害成分の探索2023
- Author(s)
  川上祐生、伊澤歩、岩岡裕二、戸田圭祐、津嘉山泉、山本登志子、伊東秀之、高橋吉孝
- Organizer
  第77回日本栄養・食糧学会大会
- Data Source
  KAKENHI-PROJECT-20K11515
[Presentation] ナツメグ含有成分malabaricone Cによる5-リポキシゲナーゼ活性阻害と気管支喘息改善効果2023
- Author(s)
  川上祐生、津嘉山泉、戸田圭祐、伊東秀之、高橋吉孝、山本登志子
- Organizer
  第96回日本生化学会大会（福岡）
- Data Source
  KAKENHI-PROJECT-20K11515
[Presentation] Malabaricone C derived from nutmeg inhibits arachidonate 5-lipoxygenase activity ameliorating murine psoriasis-like skin inflammation and OVA-induced allergic airway inflammation2023
- Author(s)
  Toshiko Suzuki-Yamamoto, Izumi Tsukayama, Yuki Kawakami, Asako Tamenobu, Keisuke Toda, Saya Maruoka, Hideyuki Ito, Yoshitaka Takahashi, Yoshimi Miki, Makoto Murakami
- Organizer
  ICBL 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K11515
[Presentation] ナツメグ由来malabaricone Cによる5-リポキシゲナーゼ活性阻害と乾癬改善効果2023
- Author(s)
  津嘉山泉、川上祐生、為延麻子、戸田圭祐、丸岡紗也、長崎祐樹、高橋吉孝、三木寿美、村上誠、山本登志子
- Organizer
  第65回　日本脂質生化学会（熊本）
- Data Source
  KAKENHI-PROJECT-23K10921
[Presentation] ナツメグ由来malabaricone Cによる5-リポキシゲナーゼ活性阻害と乾癬改善効果2023
- Author(s)
  津嘉山泉、川上祐生、為延麻子、戸田圭祐、丸岡紗也、長崎祐樹、高橋吉孝、三木寿美、村上誠、山本登志子
- Organizer
  第65回　日本脂質生化学会（熊本）
- Data Source
  KAKENHI-PROJECT-20K11515
[Presentation] 非アルコール性脂肪性肝炎の進展に寄与する12-リポキシゲナーゼの解明2021
- Author(s)
  戸田圭祐、森香子、川上祐生、神崎圭太、玉井玲名、田中龍舞、津嘉山泉、山本登志子、川上貴代、高橋吉孝
- Organizer
  第63回日本脂質生化学会
- Data Source
  KAKENHI-PROJECT-20K11515
[Presentation] NASHモデルマウス肝で発現上昇する血小板型12S-リポキシゲナーゼ2021
- Author(s)
  田中龍舞、森香子、川上祐生、神崎圭太、津嘉山泉、川上貴代、山本登志子、高橋吉孝
- Organizer
  第75回日本栄養・食糧学会大会
- Data Source
  KAKENHI-PROJECT-20K11515
[Presentation] チェリー・オブ・ザ・リオ・グランデ葉抽出物による5-リポキシゲナーゼ阻害2020
- Author(s)
  川上祐生、神崎真由香、桐岡佐妃、津嘉山泉、岩岡裕二、伊東秀之、山本登志子、高橋吉孝
- Organizer
  日本農芸化学会2020年度大会
- Data Source
  KAKENHI-PROJECT-16K08916
[Presentation] 食品によるアラキドン酸代謝酵素の活性制御に及ぼす加熱の影響2020
- Author(s)
  川上祐生、吉岡裕美、津嘉山泉、山本登志子、高橋吉孝
- Organizer
  第74回日本栄養・食糧学会大会
- Data Source
  KAKENHI-PROJECT-18K11080
[Presentation] Platelet-type 12S-lipoxygenase in hepatic stellate cells of non-alcoholic steatohepatitis model mice2020
- Author(s)
  Keisuke Toda, Yoshiko Mori, Yuki Kawakami, Keita Kanzaki, Rena Tamai, Ryoma Tanaka, Izumi Tsukayama, Toshiko Suzuki-Yamamoto, Takayo Kawakami, Yoshitaka Takahashi
- Organizer
  4-ISPMF
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K11515
[Presentation] 非アルコール性脂肪性肝炎で上昇する12-リポキシゲナーゼアイソザイム2019
- Author(s)
  森香子、川上祐生、神崎圭太、大槻朱美、木村優花、神治響、田中龍舞、津嘉山泉、北條奈々、山本登志子、川上貴代、高橋吉孝
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-16K08916
[Presentation] Monoterpene glycosides from Qing Shan Lu Shui tea irreversibly inhibit the catalytic activity of leukocyte-type 12-lipoxygenase2019
- Author(s)
  uki Kawakami, Akemi Otsuki, Yoshiko Mor, Keita Kanzaki, Toshiko Suzuki-Yamamoto, Ding Zhi Fang, Hideyuki Ito, Yoshitaka Takahashi
- Organizer
  ICBL2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08916
[Presentation] 5-リポキシゲナーゼ活性を抑制するナツメグ含有成分による気管支喘息の軽減作用2018
- Author(s)
  川上祐生、森香子、戸田圭祐、神崎圭太、山本登志子、伊東秀之、高橋吉孝
- Organizer
  _第72回日本栄養・食糧学会大会
- Data Source
  KAKENHI-PROJECT-16K08916
[Presentation] Mutations of anti-leukotriene C4 single-chain antibody change the antigen binding specificity2018
- Author(s)
  Yuki Kawakami, Mai Kinoshita, Yoshiko Mori, Shuji Okochi, Shiori Hirano, Keita Kanzaki, Toshiko Suzuki-Yamamoto, Masumi Kimoto, Mitsuaki Sugahara, Tetsuya Hori, Hiromichi Saino, Masashi Miyano, Yoshitaka Takahashi
- Organizer
  BAO2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08916
[Presentation] 抗ロイコトリエンC4単鎖抗体の変異体による抗原結合特異性の変化2017
- Author(s)
  川上祐生1、金山友紀1、新庄望良野1、神崎圭太1、山本登志子1、菅原光明2、齊野廣道3、宮野雅司2,3、山本尚三4、高橋吉孝1
- Organizer
  第59回日本脂質生化学会
- Data Source
  KAKENHI-PROJECT-16K08916
[Presentation] Mutations of anti-leukotriene C4 single-chain antibody that change the antigen binding specificity2017
- Author(s)
  Yuki Kawakami 1, Mai Kinoshita 1, Yoshiko Mori 1, Shuji Okochi 1, Toshiko Suzuki-Yamamoto 1, Mitsuaki Sugahara 2, Tetsuya Hori 2, Hiromichi Saino 3, Masashi Miyano 2,3, Yoshitaka Takahashi 1
- Organizer
  58ｔｈ ICBL2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08916
[Presentation] Identification of 12-lipoxygenase isozyme in NASH model mice2016
- Author(s)
  Yoshiko Mori, Keita Kanzaki, Yuki Kawakami, Toshiko Suzuki-Yamamoto, Hiromi Yamashita, Yoshitaka Takahashi
- Organizer
  The 10th Joint Conference on Nutrition and Food Science
- Place of Presentation
  Woosong University, Daejeon, Korea
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08916
[Presentation] 非アルコール性脂肪性肝炎進展における12-リポキシゲナーゼの役割2016
- Author(s)
  森香子、大槻朱美、川上祐生、神崎圭太、山本登志子、川上貴代、木本眞順美、山下広美、辻英明、高橋吉孝
- Organizer
  第７０回日本栄養・食糧学会大会
- Place of Presentation
  武庫川女子大学
- Year and Date
  2016-05-13
- Data Source
  KAKENHI-PROJECT-16K08916
[Presentation] 慢性炎症性疾患の新規治療法の開発を目指す基礎研究2016
- Author(s)
  高橋吉孝, 川上祐生, 森　香子, 大河内脩史
- Organizer
  OPUフォーラム2016
- Place of Presentation
  岡山
- Year and Date
  2016-05-27
- Data Source
  KAKENHI-PROJECT-25460657
[Presentation] 非アルコール性脂肪性肝炎モデルマウス肝における血小板型12S-リポキシゲナーゼの発現上昇2016
- Author(s)
  森香子、大槻朱美、川上祐生、神崎圭太、山本登志子、川上貴代、木本眞順美、山下広美、高橋吉孝、
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台国際センター
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-16K08916
[Presentation] 抗ロイコトリエン抗体の肺線維症治療薬としての応用を目指した研究2015
- Author(s)
  高橋吉孝
- Organizer
  川崎医科大学学術集会
- Place of Presentation
  岡山
- Year and Date
  2015-08-01
- Invited
- Data Source
  KAKENHI-PROJECT-25460657
[Presentation] 肺線維症に対する抗体治療薬の開発を目指した基礎研究2015
- Author(s)
  高橋吉孝, 川上祐生, 山本登志子, 大河内脩史
- Organizer
  OPUフォーラム2015
- Place of Presentation
  岡山
- Year and Date
  2015-05-29
- Data Source
  KAKENHI-PROJECT-25460657
[Presentation] 炎症性疾患に対する抗体治療薬の開発をめざした基礎研究2014
- Author(s)
  高橋吉孝
- Organizer
  OPUフォーラム2014
- Place of Presentation
  岡山
- Year and Date
  2014-05-29
- Data Source
  KAKENHI-PROJECT-25460657
[Presentation] 40Sリボソームタンパク質サブユニット2(RPS2)はラット組織における主要なアルギニンメチル化タンパク質である2014
- Author(s)
  森本亮祐, 大森由香子, 鈴木麻希子, 野村奈央, 山本登志子, 山下広美, 高橋吉孝, 辻英明, 木本眞順美
- Organizer
  第68回日本栄養・食糧学会大会
- Place of Presentation
  酪農学園大学
- Data Source
  KAKENHI-PROJECT-23590683
[Presentation] 部位特異的変異体を用いた抗ロイコトリエンC4単鎖抗体の抗原結合に関与するアミノ酸の同定2013
- Author(s)
  木下麻衣、勝原加奈子、川上祐生、菅原光明、堀哲哉、齊野廣道、宮野雅司、山本尚三、高橋吉孝
- Organizer
  第86回日本生化学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-25460657
[Presentation] Single-chain Antibody That Neutralizes Effects of Cysteinyl Leukotrienes2013
- Author(s)
  Yoshitaka Takahashi
- Organizer
  Symposium on Advancesof Biomaterials and Regenerative Medicine
- Place of Presentation
  Taipei
- Invited
- Data Source
  KAKENHI-PROJECT-25460657
[Presentation] マウス海馬におけるタンパク質の非対称性アルギニンメチル化に及ぼす加齢と高脂肪食の影響2013
- Author(s)
  鈴木麻希子, 守谷智恵, 山本登志子, 山下広美, 高橋吉孝, 辻英明, 木本眞順美
- Organizer
  第67回日本栄養・食糧学会大会
- Place of Presentation
  名古屋大学
- Year and Date
  2013-05-24
- Data Source
  KAKENHI-PROJECT-23590683
[Presentation] ロイコトリエン単鎖抗体を利用した炎症性疾患治療薬の開発を目指した研究2013
- Author(s)
  木下麻衣、大槻朱美、森香子、勝原加奈子、川上祐生、山本登志子、高橋吉孝
- Organizer
  おかやまバイオアクティブ研究会第42回シンポジウム
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-25460657
[Presentation] Proteomic analysis of arginine methylated proteins in rat brain2013
- Author(s)
 Kimoto M, Hatakenaka H, Suzuki- Yamamoto T, Suzuki M, Ito A, Yokoro M, Yamashita H, Takahashi Y
- Organizer
 20^<th> International Congress of Nutrition
- Place of Presentation
 Spain, Granada
- Data Source
 KAKENHI-PROJECT-23590683
[Presentation] Proteomic analysis of arginine metylated proteins in rat brain.2013
- Author(s)
  Kimoto M, Hatakenaka H, Suzuki-Yamamoto T, Suzuki M, Ito A, Yokoro M, Yamashita H, Takahashi Y.
- Organizer
  20th International Congress of Nutrition
- Place of Presentation
  グラナダ、スペイン
- Data Source
  KAKENHI-PROJECT-23590683
[Presentation] 抗ロイコトリエン単鎖抗体を利用した抗体創薬に向けての基礎研究2013
- Author(s)
  高橋　吉孝、川上　祐生、山本　登志子、福島　光夫
- Organizer
  岡山県立大学OPUフォーラム
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-25460657
[Presentation] ラット組織におけるアルギニンメチル化タンパク質の検索と同定2013
- Author(s)
  森本亮祐、大森由香子、鈴木麻希子、野村奈央、山本登志子、山下広美、高橋吉孝、木本眞順美
- Organizer
  第46回日本栄養・食糧学会中国・四国支部大会
- Place of Presentation
  山口県立大学
- Data Source
  KAKENHI-PROJECT-23590683
[Presentation] マウス海馬におけるタンパク質の非対称性アルギニンメチル化に及ぼす加齢と高脂肪食の影響2013
- Author(s)
  鈴木麻希子、守谷智恵、山本登志子、山下広美、高橋吉孝、坪井誠二、辻英明、木本眞順美
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23590683
[Presentation] ADMAの産生代謝機構としての血球細胞の役割の解明2012
- Author(s)
  横路三有紀, 鈴木麻希子, 室田佳恵子, 守谷智恵, 山下広美, 高橋吉孝, 辻英明, 奥田誠也, 木本眞順美
- Organizer
  第12回日本NO学会学術集会
- Place of Presentation
  神戸国際会議場（神戸市）
- Year and Date
  2012-06-29
- Data Source
  KAKENHI-PROJECT-23590683
[Presentation] 海馬におけるproteasome subunit alpha type-2のADMA化に及ぼす加齢の影響2012
- Author(s)
  鈴木麻希子, 横路三有紀, 山本登志子, 山下広美, 高橋吉孝, 辻英明, 木本眞順美
- Organizer
  第66回日本栄養・食糧学会大会
- Place of Presentation
  東北大学
- Year and Date
  2012-05-18
- Data Source
  KAKENHI-PROJECT-23590683
[Presentation] L6筋管細胞におけるエネルギー代謝に及ぼす酢酸の影響2011
- Author(s)
  田中あや、丸田ひとみ、我如古菜月、木本眞順美、辻英明、高橋吉孝、山下広美
- Organizer
  日本農芸化学会中四国支部第29回講演会
- Place of Presentation
  徳島大学
- Year and Date
  2011-01-22
- Data Source
  KAKENHI-PROJECT-21580150
[Presentation] L6筋管細胞分化過程におけるAMPKαおよびMEF2Aの細胞内局在変化とそれらのリン酸化に及ぼす酢酸の影響2011
- Author(s)
  田中あや、丸田ひとみ、我如古菜月、木本真順美、辻英明、高橋吉孝、山下広美
- Organizer
  日本農芸化学会2010年度大会
- Place of Presentation
  京都女子大学(京都市)
- Year and Date
  2011-03-27
- Data Source
  KAKENHI-PROJECT-21580150
[Presentation] 動物のエネルギー代謝における運動トレーニングと酢酸摂取の影響2011
- Author(s)
  山口由美子、小倉千明、松田知果、森はるか、我如古菜月、木本眞順美、辻英明、高橋吉孝、山下広美
- Organizer
  第44回日本栄養・食糧学会中国・四国支部大会
- Place of Presentation
  岡山県立大学(総社市)
- Year and Date
  2011-11-13
- Data Source
  KAKENHI-PROJECT-21580150
[Presentation] 動脈硬化ならびに関連疾患の予防法確立を目指した研究2011
- Author(s)
  高橋吉孝
- Organizer
  OPUフォーラム2011
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-20500713
[Presentation] 動物のエネルギー代謝における運動トレーニングと酢酸摂取の影響2011
- Author(s)
  山口由美子、小倉千明、我如古菜月、木本眞順美、辻英明、高橋吉孝、山下広美
- Organizer
  第65回日本栄養・食糧学会大会
- Place of Presentation
  お茶の水女子大学(東京都)
- Year and Date
  2011-05-14
- Data Source
  KAKENHI-PROJECT-21580150
[Presentation] L6細胞における分化レベルによるAMPKおよびMEF2Aの細胞内局在変化とそれらに及ぼす酢酸の影響2011
- Author(s)
  田中あや、丸田ひとみ、我如古菜月、木本眞順美、辻英明、高橋吉孝、山下広美
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  国立京都国際会館(京都市)
- Year and Date
  2011-09-23
- Data Source
  KAKENHI-PROJECT-21580150
[Presentation] 赤血球タンパク質アルギニンメチル基転移酵素 Iの複合体形成と酵素活性相関2011
- Author(s)
  横路三有紀, 鈴木麻希子, 新垣友加里, 大塚智恵, 高橋吉孝, 山下広美, 辻英明, 木本眞順美
- Organizer
  第84回日本生化学大会
- Place of Presentation
  国際会議場（京都）
- Year and Date
  2011-09-22
- Data Source
  KAKENHI-PROJECT-23590683
[Presentation] マクロファージの免疫能に及ぼす酢酸の影響2011
- Author(s)
  丸山祐佳、土井絵梨子、中田和江、我如古菜月、木本眞順美、辻英明、高橋吉孝、山下広美
- Organizer
  平成23年度日本農芸化学会西日本支部・中四国支部合同大会
- Place of Presentation
  宮崎大学(宮崎市)
- Year and Date
  2011-09-17
- Data Source
  KAKENHI-PROJECT-21580150
[Presentation] 生活習慣病の早期発見と予防に向けた研究2010
- Author(s)
  高橋吉孝
- Organizer
  OPUフォーラム2010
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-20500713
[Presentation] Identification of leukocyte-type 12-lipoxygenase inhibitor in guava leaf extract. Bioactive Okayama 20102010
- Author(s)
  高橋吉孝
- Organizer
  International Conference on Biologically-Active Substances
- Place of Presentation
  Okayama
- Data Source
  KAKENHI-PROJECT-20500713
[Presentation] Identification of leukocyte-type 12-lipoxygenase inhibitor in guava leaf extract2010
- Author(s)
  高橋吉孝
- Organizer
  Bioactive Okayama 2010 International Conference on Biologically-Active Substances
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-20500713
[Presentation] 3T3-L1脂肪細胞における酢酸の影響2010
- Author(s)
  山下広美、熊野愛恵、横田博美、中野裕子、小宮山展子、木本眞順美、高橋吉孝、辻英明
- Organizer
  日本農芸化学会2010年度大会
- Place of Presentation
  東京大学駒場キャンパス
- Year and Date
  2010-03-28
- Data Source
  KAKENHI-PROJECT-21580150
[Presentation] L6筋管細胞のAMPK活性化とエネルギー代謝に及ぼす酢酸の影響2010
- Author(s)
  田中あや、丸田ひとみ、我如古菜月、木本眞順美、辻英明、高橋吉孝、山下広美
- Organizer
  第83回日本生化学会大会
- Place of Presentation
  神戸ポートアイランド
- Data Source
  KAKENHI-PROJECT-21580150
[Presentation] 脂質異常症の病態2009
- Author(s)
  高橋吉孝
- Organizer
  21年度岡山県栄養士会生涯学習研修会講演
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-20500713
[Presentation] ポリフェノールの生活習慣病予防への応用を目指したアラキドン酸代謝に関する基礎研究2008
- Author(s)
  高橋吉孝
- Organizer
  第4回「酢の機能性活用コンソーシアム」研究発表・セミナー
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-20500713

1. KAWAKAMI Yuki (30453202)

# of Collaborated Projects: 5 results

# of Collaborated Products: 37 results
2. KIMOTO Masumi (40108866)

# of Collaborated Projects: 2 results

# of Collaborated Products: 23 results
3. YAMAMOTO Shozo (50025607)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. HAYASHI Yoko (60035441)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. YOSHIMOTO Tanihiro (60127876)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. JISAKA Mitsuo (60243424)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. YOKOTA Kazushige (90158361)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. NAGAYA Tsutomu (50284021)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. NISHIMURA Kohji (30304257)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. YAMASHITA Hiromi (70254563)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
11. YAMAMOTO Toshiko (60301313)

# of Collaborated Projects: 1 results

# of Collaborated Products: 14 results
12. SUZUKI Makiko (60437001)

# of Collaborated Projects: 1 results

# of Collaborated Products: 13 results
13. MIYANO Masashi (80332287)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
14. TOH Hiroyuki (70192656)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. UEDA Natsuo (20193807)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. SUZUKI Hiroshi (80253194)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. HIGUCHI Yoshihiro (10019630)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. MURAKAMI Takashi (40210009)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 戸田圭祐 (80881630)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
20. HUKUZAWA Kenji

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. MARUTA Hitomi

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
22. ARAKI Aya

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
23. 矢部大介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 清野進

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 津嘉山泉

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
26. 吉村征浩

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
27. 山本圭

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Takahashi Yoshitaka 高橋 吉孝

TAKAHASHI Yoshitaka 高橋 吉孝

TAKAHASHI Yashitaka 高橋 吉孝

高橋 吉孝 タカハシ ヨシタカ

Research Projects

Research Products

Co-Researchers

NASHの肝線維化過程における血小板型12－リポキシゲナーゼの役割の解明Principal Investigator

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Does platelet-type 12-lipoxygenase play any role in the development of fibrosis in NASH?Principal Investigator

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Study on effect of changes in food ingredients on the catalytic activities of arachidonic acid-metabolizing enzymes

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Study aiming for the development of NASH prevention focusing on lipoxygenasePrincipal Investigator

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Study on anti-leukotriene single-chain antibody aiming to develop medicines for chronic inflammatory diseasesPrincipal Investigator

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Searching for neurodegenerative disease-related factors in the metabolic systems of ADMA-containing protein and the elucidation of the functional mechanism

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Studies on the protective effect of acetate on metabolic syndrome

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Study for the development of a novel treatment to prevent atherosclerosis with guava teaPrincipal Investigator

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Metabolism of n-3 polyunsaturated fatty acids by lipoxygenases and production of novel bioactive agents

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Investigation of the functional molecules and mechanism on the LDL oxidation causing atherosclerosis -essential roles of 12/15-lipoxygenase-Principal Investigator

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Pathophysiological role of lipid molecules produced by 12/l5-lipoxygenase

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ヒト乳癌細胞の増殖ならびに浸潤転移におけるエイコサノイドの役割Principal Investigator

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Molecular biological studies on cyclooxygenases and lipoxygenases dynamics

Takahashi Yoshitaka 高橋吉孝

TAKAHASHI Yoshitaka 高橋吉孝

TAKAHASHI Yashitaka 高橋吉孝

高橋吉孝タカハシヨシタカ