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murakami takashi
村上 尚
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Alternative Names
MURAKAMI Takashi 村上 尚
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Researcher Number
40210009
Other IDs
Affiliation (Current)
2020: 高知県立大学, 健康栄養学部, 教授
Affiliation (based on the past Project Information)
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2003 – 2005: 金沢大学, 医学系研究科, 助教授
2002 – 2003: 金沢大学, 大学院・医学系研究科, 助教授
1997 – 2000: School of Medicine, The University of Tokushima Instructor, 医学部, 助手
1996: 徳島大学, 医学部・付属病院, 助手
1995: The University of Tokushima, Institute for Enzyme Research, Research Associate, 酵素科学研究センター, 助手
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1994 – 1995: 徳島大学, 医学部, 助手
1989 – 1993: 徳島大学, 酵素科学研究センター, 助手
1991 – 1992: 徳島大学, 助手
Less
Review Section/Research Field
Principal Investigator
Pathological medical chemistry
/
General medical chemistry
/
Urology
Except Principal Investigator
General medical chemistry
/
内分泌・代謝学
/
Kidney internal medicine
/
Pathological medical chemistry
/
Metabolomics
/
Laboratory medicine
/
Pathological medical chemistry
Keywords
Principal Investigator
octn2 / THP / グルコーストランスポーター / エンハンサー / SRE / SP1 / AP1 / 肥満関連遺伝子 / obese / ob
…
More
/ クローニング / 発現誘導 / カルニチン / カルニチン輸送担体 / 妊よう性 / JVSマウス / 無精子症 / octn 2 / 精巣上体 / 全身性カルニチン欠乏マウス / 閉塞性無精子症 / carnitine / carintine transporter / infertility / JVS mouse / epidiymis / azoospermia
…
More
Except Principal Investigator
糖尿病 / インスリン / グルコーストランスポーター / シグナル伝達 / インスリンレセプタ- / インスリンシグナル伝達 / トランスロケーション / octn2 / ヒトインスリンレセプタ- / PIー3キナ-ゼ / 遺伝子工学 / トランスジェニックマウス / グルコース取り込み / インスリン抵抗性 / メサンギウム細胞 / Insulin signal transduction / カルニチン / カルニチン輸送担体 / 細胞増殖 / チロシンキナ-ゼ / 機能材料 / 異常インスリンレセプタ- / グルコ-ストランスポ-タ- / インスリンレセプター / PI-3キナーゼ / PI3-キナーゼ / OLETF / インスリンレセプタ-遺伝子異常 / Insulin Receptor / カルニチントランスポーター / 低血糖症 / hypoglycemia / 2型糖尿病 / 糸球体硬化症 / TGF-β / MSW / mesangial cell / glomerulosclerosis / JVSマウス / carnitine / JVS mouse / STAT3 / 12 / 受容体 / チロシンキナーゼ / 糖尿病モデルマウス / トランスジェニック / 3T3-L1細胞 / 脂肪細胞 / 分化誘導因子 / インスリンレセプタ-遺伝子 / グルコ-ストランスポ-タ-遺伝子 / グルコ-ストランスポ-タ-タイプI / エンハンサ- / タンパク質の局在化 / インスリンレセプタ-異常 / 機能性材料 / ヒトインスリンレセプター / 異常インスリンレセプター / インスリンセプター異常 / インスリンレセプター異常 / PCR / GTP結合蛋白質 / グルコーストランスポータータイプ4 / インスリン作用 / エキソサイトーシス / Gタンパク / 腹腔内脂肪 / FFA / 食事制限 / リボザイム / 糖化終末産物 / RAGE / IV型コラーゲン / HSP47 / 糖尿病腎症 / 遺伝子発現 / Sp1 / Insulin receptor / Gene expression / 遺伝子診断 / NIDDM / Mutation / PI 3-kinase / PI 3-キナーゼ / 細胞増殖因子 / GTP結合タンパク質 / PI3-kinase / GLUT4 translocation / G-proteins / 脂肪肝 / 原発性カルニチン欠乏症 / 心肥大 / ミトコンドリア / 高アンモニア血症 / Carnitine / Carnitine Transporter / fatty liver / primary carnitine deficiency / cardiomegaly / mitochondria / hyperammonemia / B細胞増殖能 / B細胞量 / インスリン分泌 / 細小血管症 / 脂肪滴 / LETO / 部分膵切除 / β細胞増殖能 / 胎児ラ氏島様細胞集塊 / β細胞量 / 膵管上皮細胞 / β細胞インスリン含量 / Tvpe2DM / beta-cell proliferation / beta-cell mass / insulin secretion / insulin resistance / microangiopathy / fat droplet / 転写因子 / プロモーター / 核転送 / transcription factor / promoter / 乳酸 / ピルビン酸 / Na^+依存性 / 心筋細胞 / OCTN^2 / ポジショナルクローニング / β-酸化 / JVS マウス / carnitine transporter / lactate / pyruvate / NaィイD1+ィエD1 dependency / 増殖 / Gas6 / 増殖因子 / ワーファリン / 糸球体腎炎 / ビタミンK / Axl / Gla化蛋白 / 増殖抑制 / Erk / proliferation / Gas 6 / growth factor / warfarin / vitamin K / octn 2 / グルカゴン / 2-DG取り込み / 脂肪酸 / 膵β細胞 / 長鎖脂肪酸 / 高血糖 / 脂肪毒性 / 膵ラ氏島 / carintine transporter / insulin / glucagon / 2-DG uptake / fatty acid / 肝硬変 / 門脈グルコースセンサー / 血小板 / レプチン / Insulin resistance / diabetes mellitus / liver cirrhosis / portal glucosensor / platelet / 15-リポキシゲナーゼ / マクロファージ / 酸化LDL / LDL受容体関連蛋白 / コレステロールエステル / 15-リポシゲナーゼ / 15-Lipoxygenase / Macrophage / Oxidized LDL / LDL-receptor-related protein / Cholesteryl ester / グルタミン酸 / グリア細胞腫 / アポトーシス / ネクローシス / グルタチオン枯渇 / 紫外線照射 / 巨大DNA断片化 / 脂質過酸化 / DNA損傷 / 8-ヒドロキシグアノシン / スパーゼ / 紫外線 / 酸素フリーラジカル / ポリ(ADP-リボース)ポリメラーゼ / アラキドン酸 / ATP / グルタチオン / 12-リポオキシゲナーゼ / 不飽和脂肪酸 / Glutamate / Glia / Apoptosis / Necrosis / Glutathione / Ultraviolet / Giant DNA fragmentation / Lipid peroxidation
Less
Research Projects
(
42
results)
Co-Researchers
(
25
People)
Project Start Year (Newest)
Project Start Year (Oldest)
The study on the glutamate-induced glial cell death mechanism for modulation of apoptosis to necrosis by arachidonic acid-mediated lipid peroxidation
Principal Investigator
HIGUCHI Yoshihiro
Project Period (FY)
2003 – 2005
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Pathological medical chemistry
Research Institution
Kanazawa University Graduate School of Medical Science
Investigation of the functional molecules and mechanism on the LDL oxidation causing atherosclerosis -essential roles of 12/15-lipoxygenase-
Principal Investigator
TAKAHASHI Yoshitaka
Project Period (FY)
2002 – 2003
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
General medical chemistry
Research Institution
KANAZAWA UNIVERSITY
The Study of Progressive Factors to Developing Glomerular Injury
Principal Investigator
DOI Toshio
Project Period (FY)
2000 – 2002
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
Kidney internal medicine
Research Institution
The University of Tokushima
Is lipotoxicity caused by the intracellular accumulation ofacyl CoA ?
Principal Investigator
KUWAJIMA Masamichi
Project Period (FY)
2000 – 2001
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
Metabolomics
Research Institution
The University of Tokushima
Trials for the evaluation of hepatic insulin resistance with novel simplified method using platelet
Principal Investigator
MIZUNO Akira
Project Period (FY)
2000 – 2001
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Laboratory medicine
Research Institution
The University of Tokushima
Hammer-head型リボザイムによる遺伝子発現抑制の腎疾患への応用
Principal Investigator
DOI Toshio
Project Period (FY)
1999 – 2000
Research Category
Grant-in-Aid for Exploratory Research
Research Field
Kidney internal medicine
Research Institution
The University of Tokushima
Investigation for progressive factors of glomerulosclerosis.
Principal Investigator
DOI Toshio
Project Period (FY)
1998 – 1999
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
Kidney internal medicine
Research Institution
The University of Tokushima
Kyoto University
Positional cloning of carnitine transporter gene and its contribution on hypoglycemia.
Principal Investigator
KUWAJIMA Masamichi
Project Period (FY)
1998 – 1999
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
Metabolomics
Research Institution
The University of Tokushima
Analysis of infertility in systemic carnitine deficient mouse (JVS mouse)
Principal Investigator
Principal Investigator
MURAKAMI Takashi
Project Period (FY)
1998 – 1999
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Urology
Research Institution
The University of Tokushima
The etiological importance of reduced B-cell masses for the development of type 2 diabetes mellitus.
Principal Investigator
SHIMA Kenji
Project Period (FY)
1997 – 1998
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
内分泌・代謝学
Research Institution
The University of Tokushima
Positional cloning of carnitine trasporter gene and its comtribution to the pathophysiological changes
Principal Investigator
KUWAJIMA Masamichi
Project Period (FY)
1996 – 1997
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
内分泌・代謝学
Research Institution
The University of Tokushima
腹腔内脂肪蓄積のインスリン抵抗性への病因的関連
Principal Investigator
SHIMA Kenji
Project Period (FY)
1995 – 1996
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
内分泌・代謝学
Research Institution
The University of Tokushima
細胞増殖および癌化におけるグルコーストランスポーター遺伝子活性化機構の解析
Principal Investigator
Principal Investigator
村上 尚
Project Period (FY)
1995
Research Category
Grant-in-Aid for Encouragement of Young Scientists (A)
Research Field
Pathological medical chemistry
Research Institution
The University of Tokushima
グルコーストランスポーターの細胞内局在変化の分子メカニズムとインスリン作用
Principal Investigator
蛯名 洋介
Project Period (FY)
1994
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
The University of Tokushima
インスリン作用とGTP結合蛋白質
Principal Investigator
蛯名 洋介
Project Period (FY)
1994
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
The University of Tokushima
インスリンシグナル伝達における蛋白質高次構造認識機構
Principal Investigator
蛯名 洋介
Project Period (FY)
1994
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
The University of Tokushima
インスリンによる細胞内のグルコース取り込み促進の分子メカニズムの解明
Principal Investigator
林 日出喜
Project Period (FY)
1994
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
General medical chemistry
Research Institution
The University of Tokushima
Molecular mechanisms of insulin signal transduction and diabetes mellitus
Principal Investigator
EBINA Yousuke
Project Period (FY)
1994 – 1995
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Pathological medical chemistry
Research Institution
The University of Tokushima
グルコーストランスポーターの細胞内局在変化の分子メカニズムとインスリン作用
Principal Investigator
蛯名 洋介
Project Period (FY)
1993
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
The University of Tokushima
インスリンレセプター遺伝子異常と糖尿病
Principal Investigator
蛯名 洋介
Project Period (FY)
1993
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
The University of Tokushima
インスリン作用とGTP結合蛋白質
Principal Investigator
蛯名 洋介
Project Period (FY)
1993
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
The University of Tokushima
インスリンシグナル伝達におけるフォスファチジル・イノシトール-3キナーゼの役割
Principal Investigator
林 日出喜
Project Period (FY)
1993
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
General medical chemistry
Research Institution
The University of Tokushima
細胞増殖および癌化におけるグルコーストランスポーター遺伝子活性化機構の解析
Principal Investigator
Principal Investigator
村上 尚
Project Period (FY)
1993
Research Category
Grant-in-Aid for Encouragement of Young Scientists (A)
Research Field
Pathological medical chemistry
Research Institution
The University of Tokushima
生体受容体を機能性材料として開発するための基礎的研究
Principal Investigator
蛯名 洋介
Project Period (FY)
1992
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
The University of Tokushima
ヒト異常インスリン受容体遺伝子導入による糖尿病モデルマウスの作製
Principal Investigator
蛯名 洋介
Project Period (FY)
1992
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
The University of Tokushima
インスリンレセプター遺伝子異常と糖尿病
Principal Investigator
蛯名 洋介
Project Period (FY)
1992
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
The University of Tokushima
細胞増殖および癌化におけるグルコーストランスポーター遺伝子活性化機構の解析
Principal Investigator
Principal Investigator
村上 尚
Project Period (FY)
1992
Research Category
Grant-in-Aid for Encouragement of Young Scientists (A)
Research Field
Pathological medical chemistry
Research Institution
The University of Tokushima
生体受容体を機能材料として開発するための基礎的研究
Principal Investigator
蝦名 洋介
Project Period (FY)
1991
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
The University of Tokushima
ヒト異常インスリン受容体遺伝子導入による糖尿病モデルマウスの作製
Principal Investigator
蝦名 洋介
Project Period (FY)
1991
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
The University of Tokushima
インスリン刺激によるグルコ-ストランスポ-タ-の細胞内局在変化の分子メカニズム
Principal Investigator
蛯名 洋介
Project Period (FY)
1991
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
The University of Tokushima
インスリンレセプタ-遺伝子異常と糖尿病
Principal Investigator
蛯名 洋介
Project Period (FY)
1991
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
The University of Tokushima
細胞増殖および癌化におけるグルコーストランスポーター遺伝子活性化機構の解析
Principal Investigator
Principal Investigator
村上 尚
Project Period (FY)
1991
Research Category
Grant-in-Aid for Encouragement of Young Scientists (A)
Research Field
General medical chemistry
Research Institution
The University of Tokushima
Molecular mechanisms of insulin signal transduction and its disorder
Principal Investigator
EBINA Yousuke
Project Period (FY)
1991 – 1992
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Pathological medical chemistry
Research Institution
The University of Tokushima
細胞増殖シグナルによるグルコ-ストランスポ-タ-動的変化の分子機構
Principal Investigator
蛯名 洋介
Project Period (FY)
1990
Research Category
Grant-in-Aid for Cancer Research
Research Institution
The University of Tokushima
生体受容体を機能材料として開発するための基礎的研究
Principal Investigator
蛯名 洋介
Project Period (FY)
1990
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
The University of Tokushima
ヒト異常インスリン受容体遺伝子導入による糖尿病モデルマウスの作製
Principal Investigator
蛯名 洋介
Project Period (FY)
1990
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
The University of Tokushima
Establishment of a simple diagnostic method for the detection of mutations of insulin receptor gene in Non-Insulin Dependent Diabetes Mellitus
Principal Investigator
EBINA Yousuke
Project Period (FY)
1990 – 1991
Research Category
Grant-in-Aid for Developmental Scientific Research (B)
Research Field
Pathological medical chemistry
Research Institution
The University of Tokushima
細胞増殖因子受容体チロシンキナーゼによる細胞増殖の制御機構
Principal Investigator
EBINA Yousuke
Project Period (FY)
1989
Research Category
Grant-in-Aid for Cancer Research
Research Institution
The University of Tokushima
ヒト異常インスリン受容体遺伝子導入による糖尿病モデルマウスの作製
Principal Investigator
蛯名 洋介
Project Period (FY)
1989
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
The University of Tokushima
インスリンシグナル伝達機構におけるGTP結合蛋白質の役割
Principal Investigator
蛯名 洋介
Project Period (FY)
1989
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
The University of Tokushima
3T3-L1線維芽細胞から脂肪細胞への分化誘導因子の分離と精製
Principal Investigator
蛯名 洋介
Project Period (FY)
1989
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
The University of Tokushima
Structure and Function of Insulin Receptor, its Gene Expression and its Signal Transduction Mechanism
Principal Investigator
EBINA Yousuke
Project Period (FY)
1989 – 1990
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
General medical chemistry
Research Institution
The University of Tokushima
# of Projects (Dsc)
# of Projects (Asc)
1.
EBINA Yousuke
(00112227)
# of Collaborated Projects:
24 results
# of Collaborated Products:
0 results
2.
HAYASHI Hideki
(10218589)
# of Collaborated Projects:
22 results
# of Collaborated Products:
0 results
3.
MIZUNO Akira
(80219641)
# of Collaborated Projects:
8 results
# of Collaborated Products:
0 results
4.
KUWAJIMA Masamichi
(00205262)
# of Collaborated Projects:
8 results
# of Collaborated Products:
0 results
5.
NOMA Yoshihiko
(10218349)
# of Collaborated Projects:
7 results
# of Collaborated Products:
0 results
6.
DOI Toshio
(60183498)
# of Collaborated Projects:
4 results
# of Collaborated Products:
0 results
7.
SHIMA Kenji
(90028407)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
8.
TANAKA Toshihiro
(50292850)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
9.
ISHIMURA Kazunori
(90112185)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
10.
TOKINO Takashi
(40202197)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
11.
ITO Michinori
(40211057)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
12.
TOSHIMORI Kiyotaka
(20094097)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
13.
TSUKAGUCHI Hiroyasu
(60335792)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
14.
SHIMABUKURO Michio
(60271144)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
15.
TAKAHASHI Yoshitaka
(10236333)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
16.
YOSHIMOTO Tanihiro
(60127876)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
17.
HIGUCHI Yoshihiro
(10019630)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
18.
TANII Hideji
(90110618)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
19.
堀内 久徳
(90291426)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
20.
久米 典昭
(20252455)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
21.
横出 正之
(20252447)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
22.
篠原 康雄
(60226157)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
23.
石井 賢二
(00212811)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
24.
MATSUOKA Yukio
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
25.
MIYAMOTO Tadayuki
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
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