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Kume Noriaki  久米 典昭

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KUME Noriaki  久米 典昭

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Researcher Number 20252455
Affiliation (Current) 2022: 神戸学院大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help 2013 – 2018: 神戸学院大学, 薬学部, 教授
2012: 京都大学, 医学研究科, 講師
1998 – 2007: Kyoto University, Faculty of Medicine, Lecturer, 医学研究科, 講師
2005: 京都大学, 医学研究科, 助手
1999: 京都大学, 大学院・医学研究科, 講師
1995 – 1998: KYOTO UNIVERSITY,GRADUATE SCHOOL OF MEDICINE,INSTRUCTOR, 医学研究科, 助手
1993 – 1994: 京都大学, 医学部, 助手
Review Section/Research Field
Principal Investigator
Metabolomics / 内分泌・代謝学 / Circulatory organs internal medicine / Metabolomics
Except Principal Investigator
内分泌・代謝学 / Metabolomics / Kidney internal medicine / Circulatory organs internal medicine / Eating habits, studies on eating habits / Cerebral neurosurgery … More / Metabolomics / Radiation science / Neurosurgery / Environmental physiology(including physical medicine and nutritional physiology) Less
Keywords
Principal Investigator
atherosclerosis / LOX-1 / 酸化LDL / 粥状動脈硬化 / スカベンジャー受容体 / 血管内皮細胞 / lysophosphatidylcholine / oxidized LDL / 動脈硬化 / CXCR6 … More / プラーク破綻 / IL-18 / ADAM10 / 接着分子 / リゾフォスファチジルコリン / PECAM-1 / endothelial cells / tyrosine phosphorylation / アポトーシス / 平滑筋細胞 / scavenger receptor / plaque rupture / マクロファージ / ケモカイン / VCAM-1 / 血管平滑筋細胞 / 急性冠症候群 / プロテアーゼ / HB-EGF / 脂肪肝 / 炎症 / 線維化 / 肝炎 / 増殖因子 / サイフリックAMP / サイクリックAMP / endothelium / adhesion molecules / growth factors / cyclic AMP / MAPキナーゼ / チロシンリン酸化 / チロシニリン酸化 / PECANM-1 / Atherosclerosis / MAP kinases / 高脂血症 / プラーク破碇 / スカベンジカー受容体 / Bax / Bcl-2 / hyperlipidemia / apoptosis / smooth muscle cells / ガンマ・インターフェロン / 細菌 / Tリンパ球 / 弁膜疾患 / 再狭窄病変 / マトリックス・メタロプロテアーゼ / macrophages / chemokines / gamma interferon / トロンビン / メタロプロテアーゼ / 血栓 / ガンマインターフェロン / acute coronary syndrome / proteases / shedding / レムナントリポ蛋白 / 食後高脂血症 / 糖尿病 / メタボリックシンドローム / remnant lipoproteins / diabetes / metabolic syndrome / postprandial hyperlipidemia / vascular smooth muscle cells … More
Except Principal Investigator
動脈硬化 / LOX-1 / リゾフォスファチジルコリン / VCAM-1 / マクロファージ / MCP-1 / SR-PSOX / 粥状動脈硬化 / Tリンパ球 / 酸化LDL / 血管内皮細胞 / 内皮細胞 / ICAM-1 / oxidized LDL / WHHLウサギ / JAM / Egr-1 / Lysophosphatidylcholine / Rab4 / LDL / 接着分子 / WHHL-rabbit / スカベンジャー受容体 / LDL受容体 / 肝細胞 / トランスジェニックマウス / トロンビン受容体 / 平滑筋細胞増殖因子 / 酸化LDL受容体 / メサンギウム細胞 / 転写因子 / 家族性高コレステロール血症 / WHHL-ウサギ / lysophosphatidyl-choline / HB-EGF / 単球接着分子 / Atherosclerosis / MTP / VLDL / HSP-70 / TGF-β / MSW / サイトカイン / ケモカイン / 血栓 / 血小板 / atherosclerosis / iNOS / MMP / 不安定プラーク / 選別輸送 / コレステロール代謝 / THP1 / 動脈硬化症 / チロシンリン酸化 / 分化 / 平滑筋細胞 / 増殖 / IV型コラーゲン / DNA複製因子C / bHLH / E-box / Id / 海藻 / 伝統食 / 機能性成分 / 調理 / Cキナーゼ / familial hypercholesterolemia atherosclerosis / T lymphocyte / PDGF-A,B鎖 / リゾホスファチジルコリン / P selection / PDGF-A, B鎖 / P selecTin / 泡沫細胞 / endothelial cell / PDGF-A,B chain / P-selectin / T-lymphocyte / 単球 / 単クローン抗体 / malotilate / 抗動脈硬化薬 / Monocyte / Vascular endothelial cell / Macrophage / Monocyte adhesion molecule / Tlymphocyte / Athero ELAM / P selectin / HB‐EGF / PDGF / INF‐γ / IL‐2受容体 / Oxidized LDL / Lysophosphatidyl-choline / T-lymphocytes / Adhesion molecule / Smooth muscle growth factor / Macrophages / INF-gamma / コレステロール / アポ蛋白B-100 / CHO-Cell / HMG-CoA還元酵素阻害剤 / 家族性複合型高脂血症 / Cholesterol / Apo B-protein / CHO-cell / Hepatocytes / Transgenic mouse / 糸球体硬化症 / プロモーター / 核転送 / mesangial cell / transcription factor / glomerulosclerosis / promoter / 血小板活性化 / Gas6 / PDGF受容体 / 細胞接着 / 細胞遊走 / plate activation / Gsr6 / PDGF receptor / 脳動脈瘤 / endothelin / 遺伝子 / 動物モデル / 血行力学的ストレス / 高血圧 / ラット / マウス / hemodynamic stress / cerebral aneurysmal / endothelium / gene / 顆粒放出 / インテグリン / プロスタグランディン / Oxidized LDL receptor / platelet / granule secretion / integrin / prostaglandin / chemokine / 分子イメージング / 放射線検出器 / グルコース誘導体 / 放射性プローブ / 超小型放射線検出器 / F-18 / thrombosis / vulnerable plaque / molecular imaging / radiation detector / glucose derivative / lectine-like oxidized LDL receptor / macrophage / radiolabeled molecular probe / 頚動脈狭窄 / プラーク性状 / MRIプラークイメージ / 血液バイオマーカー / 頚動脈狭窄症 / バイオマーカー / MRI / 可溶性レクチン様酸化型LDL受容体-1 / プラーク内出血 / 画像診断 / 血液マーカー / 脳梗塞 / 概日時計 / 時計遺伝子 / 転写制御 / 概日リズム Less
  • Research Projects

    (26 results)
  • Research Products

    (45 results)
  • Co-Researchers

    (54 People)
  •  A metalloprotease regulates the circadian clock

    • Principal Investigator
      HIRAOKA yoshinori
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Environmental physiology(including physical medicine and nutritional physiology)
    • Research Institution
      Kobe Gakuin University
  •  Multifaceted diagnostic approach for unstable carotid artery plaque with MRI and blood biomarker

    • Principal Investigator
      Yoshida Kazumichi
    • Project Period (FY)
      2015 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurosurgery
    • Research Institution
      Kyoto University
  •  Molecular mechanism and biomarkers for non-alcoholic steatohepatitisPrincipal Investigator

    • Principal Investigator
      Kume Noriaki
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Kobe Gakuin University
  •  Wisdom of seaweed foods in fishing village ?Application to modern dishes-

    • Principal Investigator
      TOYOYHARA Masako
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Eating habits, studies on eating habits
    • Research Institution
      京都華頂大学
      Kacho Junior College
  •  Novel functions of lectin-like oxidized LDL receptor-1 (LOX-1)Principal Investigator

    • Principal Investigator
      KUME Noriaki
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Kyoto University
  •  Molecular mechanism of the process from atherosclerotic lesion formation to plaque rupture

    • Principal Investigator
      KITA Toru
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Metabolomics
    • Research Institution
      Kyoto University
  •  Molecular imaging for noninvasive evaluation of atherosclerotic plaque vulnerability

    • Principal Investigator
      SAJI Hideo
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Radiation science
    • Research Institution
      Kyoto University
  •  Oxidized LDL receptors, LOX-1 and SE-PSOX and their soluble moleculesPrincipal Investigator

    • Principal Investigator
      KUME Noriaki
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Kyoto University
  •  Pathopysiological roles of a novel oxidized LDL receptor, SR-PSOXPrincipal Investigator

    • Principal Investigator
      KUME Noriaki
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      KYOTO UNIVERSITY
  •  Elucidation of molecular mechanism of atherosclerosis formation

    • Principal Investigator
      YOKODE Msayuki
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Metabolomics
    • Research Institution
      KYOTO UNIVERSITY
  •  Molecular mechanisms of cerebral aneurysmal formation

    • Principal Investigator
      HASHIMOTO Nobuo
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Kyoto University
  •  Molecular mechanism of activation of endothelial cells involved in early stage of atherosclerosis formation.

    • Principal Investigator
      KITA Toru
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (A).
    • Research Field
      Metabolomics
    • Research Institution
      KYOTO UNIVERSITY
  •  Cell biological study for atherosclerosis

    • Principal Investigator
      KITA Toru
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (A).
    • Research Field
      Metabolomics
    • Research Institution
      KYOTO UNIVERSITY
  •  Pathophysiological roles of LOX-1, a novel receptor of oxidized LDLPrincipal Investigator

    • Principal Investigator
      KUME Noriaki
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Institution
      KYOTO UNIVERSITY
  •  メサンギウム細胞分化を決定する新たな転写因子のクローニング-腎障害の形質変換における機能解析

    • Principal Investigator
      土井 俊夫
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Kidney internal medicine
    • Research Institution
      Kyoto University
  •  Investigation for progressive factors of glomerulosclerosis.

    • Principal Investigator
      DOI Toshio
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Kidney internal medicine
    • Research Institution
      The University of Tokushima
      Kyoto University
  •  動脈硬化発症・進展の分子機構

    • Principal Investigator
      KITA Toru
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Field
      内分泌・代謝学
    • Research Institution
      Kyoto University
  •  粥状動脈硬化の発生、進展に及ぼすトロンビン受容体の影響に関する研究

    • Principal Investigator
      ISHII Kenji
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Kyoto University
  •  Expression of adhesion molecules and growth factors in vascular endothelial cellPrincipal Investigator

    • Principal Investigator
      KUME Noriaki, 越智 弘
    • Project Period (FY)
      1996 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      KYOTO UNIVERSITY
  •  Molecular mechanism on the progression of atherosclerosis.

    • Principal Investigator
      KITA Toru
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      KYOTO UNIVERSITY
  •  Development of new drug for intractable hyperlipidemia and its clinical application

    • Principal Investigator
      KITA Toru
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      内分泌・代謝学
    • Research Institution
      KYOTO UNIVERSITY
  •  発生工学を応用した小胞体輸送機構の研究-LDL受容体を発現するトランスジェニックマウスを用いて-

    • Principal Investigator
      YOKODE Masayuki
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  Regulation of VCAM-1 and ICAM-1 expression in atherogenesisPrincipal Investigator

    • Principal Investigator
      KUME Noriaki
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      内分泌・代謝学
    • Research Institution
      KYOTO UNIVERSITY
  •  Studies on the initiation and regression of atherosclerosis

    • Principal Investigator
      KITA Toru
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Kyoto University
  •  Gene engineering, cell biological aproaches to the mechanisms for early stage of atherosclerosis

    • Principal Investigator
      KITA Toru
    • Project Period (FY)
      1993 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      内分泌・代謝学
    • Research Institution
      KYOTO UNIVERSITY
  •  Development and clinical application of novel anti-atherogenic drug.

    • Principal Investigator
      KITA Toru
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      内分泌・代謝学
    • Research Institution
      KYOTO UNIVERSITY

All 2018 2017 2016 2015 2014 2013 2008 2007 2006 2005 2004

All Journal Article Presentation

  • [Journal Article] Comparison of serum lipid management between elderly and non-elderly patients with and without coronary heart disease (CHD).2016

    • Author(s)
      Nishi K, Sato Y, Ohno M, Hiraoka Y, Saijo S, Sakamoto J, Chen PM, Morita Y, Matsuda S, Iwasaki K, Sugizaki K, Harada N, Mukumoto Y, Kiyonari H, Furuyama K, Kawaguchi Y, Uemoto S, Kita T, Inagaki N, Kimura T, Nishi E.
    • Journal Title

      Prev Med Rep.

      Volume: 65 Pages: 3015-27

    • DOI

      10.1016/j.pmedr.2016.06.006

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K08536
  • [Journal Article] Plasma soluble lectin-like oxidized low-density lipoprotein receptor-1 as a novel prognostic biomarker in patients with ST-segment elevation acute myocardial infarction.2015

    • Author(s)
      Higuma T, Abe N, Tateyama S, Endo T, Shibutani S, Yokoyama H, Harada K, Yamada M, Tomita H, Hanada H, Osanai T, Kume N, Okumura K
    • Journal Title

      Cieculation Journal

      Volume: in press

    • NAID

      130004927094

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25461369
  • [Journal Article] Serum lipid goal attainment in chronic kidney disease (CKD) under the Japan Atherosclerosis Society 2012 guideline: a single center study2015

    • Author(s)
      Shimizu R, Torii H, Yasuda D, Hiraoka Y, Kitada N, Hashida T, Yoshimoto A, Kita T, Kume N
    • Journal Title

      Journal of Atherosclerosis and Thrombosis

      Volume: in press

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25461369
  • [Journal Article] MicroRNA-33b knock-in mice for an intron of sterol regulatory element-binding factor 1 (Srebf1) exhibit recuced HDL-C in vivo.2014

    • Author(s)
      Horie T, Nishino T, Baba O, Kuwabara Y, Nakao T, Nishiga M, Usami S, Izuhara M, Nakazeki F, Ide Y, Koyama S, Sowa N, Yahagi N, Shimano H, Nakamura T, Hasegawa K, Kume N, Yokode M, Kita T, Kimura T, Ono K.
    • Journal Title

      Sci Rep

      Volume: 4 Pages: 5312-5312

    • DOI

      10.1038/srep05312

    • NAID

      120005447499

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-14J05148, KAKENHI-PUBLICLY-25126701, KAKENHI-PROJECT-25293182, KAKENHI-PROJECT-25461369, KAKENHI-PROJECT-25670383, KAKENHI-PUBLICLY-26116716, KAKENHI-PROJECT-26461144, KAKENHI-PROJECT-26670147, KAKENHI-PROJECT-26670448, KAKENHI-PROJECT-26860556, KAKENHI-PLANNED-23116006
  • [Journal Article] MicroRNA-33 regulates sterol regulatory element-binding protein 1 expression in mice2013

    • Author(s)
      Horie T, Nishino T, Baba O, Kuwabara Y, Nakao T, Nishiga M, Usami S, Izuhara M, Sowa N, Yahagi N, Shimano H, Matsumura S, Inoue K, Marusawa H, Nakamura T, Hasegawa K, Kume N, Yokode M, Kita T, Kimura T, Ono K
    • Journal Title

      Nature Commun

      Volume: 4:2883 Pages: 1-12

    • DOI

      10.1038/ncomms3883

    • NAID

      120005349007

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-23116006, KAKENHI-PROJECT-23390211, KAKENHI-PUBLICLY-24116512, KAKENHI-PROJECT-24390230, KAKENHI-PROJECT-24790753, KAKENHI-PROJECT-24890094, KAKENHI-PUBLICLY-25126701, KAKENHI-PROJECT-25293182, KAKENHI-PROJECT-25461369, KAKENHI-PROJECT-25462136, KAKENHI-PROJECT-25670383
  • [Journal Article] Soluble lectin-like oxidized LDL receptor-1 (sLOX-1) as a valuable diagnostic marker for rupture of thin-cap fibroatheroma: verification by optical coherence tomography2013

    • Author(s)
      Kobayashi N, Takano M, Hata N, Kume N, Yamamoto M, Yokoyama S, Shinada T, Tomita K, Shirakabe A, Otsuka T, Seino Y, Mizuno K:
    • Journal Title

      International Journal of Cardiology

      Volume: 168 Pages: 3217-3223

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461369
  • [Journal Article] Interleukin 18 stimulates release of soluble lectin-like oxidized LDL receptor-1 (sLOX-1)2008

    • Author(s)
      Mitsuoka H, Kume N, et. al.:
    • Journal Title

      Atherosclerosis (印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590985
  • [Journal Article] Lectin-like oxidized LDL receptor-1 (LOX-1) acts as a receptor for remnant-like lipoprotein particles (RLPs) and mediates RLP-induced migration of vascular smooth muscle cells2008

    • Author(s)
      Aramaki, Y., Kume, N., et. al.
    • Journal Title

      Atherosclerosis (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590985
  • [Journal Article] Interleukin 18 stimulates release of soluble lectin-like oxidized LDL receptor-1 (sLOX-1)2008

    • Author(s)
      Mitsuoka, H., Kume, N., et. al.
    • Journal Title

      Atherosclerosis (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590985
  • [Journal Article] Interleukin 18 stimulates release of soluble lectin-like oxidized LDL receptor-1(sLOX-1)2008

    • Author(s)
      Mitsuoka H, Kume N, et. al.:
    • Journal Title

      Atherosclerosis (印刷中)

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590985
  • [Journal Article] Lectin-like oxidized LDL receptor-1(LOX-1)acts as a receptor for remnant-like lipoprotein particles(RLPs)and mediates RLP-induced migration of vascular smooth muscle cells2008

    • Author(s)
      Aramaki Y, Kume N, et. al.:
    • Journal Title

      Atherosclerosis (印刷中)

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590985
  • [Journal Article] Lectin-like oxidized LDL receptor-1 (LOX-1) acts as a receptor for remnant-like lipoprotein particles (RLPs)2008

    • Author(s)
      Aramaki Y, Kume N, et. al.:
    • Journal Title

      Atherosclerosis (印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590985
  • [Journal Article] Lectin-like oxidized LDL receptor-1 (LOX-1) expression is associated with atherosclerotic plaque instability-analysis in hypercholesterolemic rabbits.2007

    • Author(s)
      S.Ishino, T.Mukai, N.Kume, D.Asano, M.Ogawa, Y.Kuge, M.Minami, T.Kita, M.Shiomi, H.Saji.
    • Journal Title

      Atherosclerosis (印刷中)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390337
  • [Journal Article] Lectin-like oxidized LDL receptor-1 (LOX-1) expression is associated with atherosclerotic plaque instability-analysis in hypercholesterolemic rabbits.2007

    • Author(s)
      Ishino S, Mukai T, Kume N, Asano D, Ogawa M, Kuge Y, Minami M, Kita T, Shiomi M, Saji H.
    • Journal Title

      Atherosclerosis. (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390337
  • [Journal Article] Lectin-like oxidized LDL receptor-1(LOX-1)expression is associated with plaque instability-analysis in hypercholesterolemic rabbits2007

    • Author(s)
      Ishino S, Mukai T, Kume N, et. al.:
    • Journal Title

      Atherosclerosis 195

      Pages: 48-56

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590985
  • [Journal Article] Lectin-like oxidized LDL receptor-1 (LOX-1) expression is associated with plaque instability-analysis in2007

    • Author(s)
      Ishino S, Mukai T, Kume N, et. al.:
    • Journal Title

      Atherosclerosis 195

      Pages: 48-56

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590985
  • [Journal Article] Lectin-like oxidized LDL receptor-1 (LOX-1) expression is associated with plaque mstability-analysis in hypercholesterolemic rabbits2007

    • Author(s)
      Ishino, S., Mukai, T., Kume, N, et. al.
    • Journal Title

      Atherosclerosis 195

      Pages: 48-56

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590985
  • [Journal Article] A catheter-based intravascular radiation detector of vulnerable plaques.2006

    • Author(s)
      R.Hosokawa, N.Kambara, M.Ohba, T.Mukai, M.Ogawa, H.Motomura, N.Kume, H.Saji, T.Kita, R.Nohara
    • Journal Title

      J.Nucl.Med. 47(5)

      Pages: 863-867

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390337
  • [Journal Article] A catherer-based intravascular radiation detector for vulnerable plaques.2006

    • Author(s)
      R.Hosokawa, N.Kambara, M.Ohba, T.Mukai, M.Ogawa, H.Motomura, N.Kume, H.Saji, T.Kita, R.Nohara
    • Journal Title

      J. Nucl. Med. 47・5

      Pages: 863-867

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390337
  • [Journal Article] Serum soluble lectin-like oxidized low-density lipoprotein receptor-1 levels are elevated in acute coronary syndrome. A novel marker for early diagnosis2005

    • Author(s)
      Hayashida, K., Kume, N., Murase, T., Minami, M., Nakagawa, D., Inada, T., Tanaka, M., Ueda, A., Kominami, G., Kambara, H., Kimura, T., Kita, T
    • Journal Title

      Circulation 112

      Pages: 812-818

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590880
  • [Journal Article] CXCL16 is a novel angiogenic factor for human umbilical vein endothelial cells.2005

    • Author(s)
      Zhuge X, . Murayama T, Arai H, Yamauchi R, Tanaka M, Shimaoka T, Yonehara S, Kume N, Yokode M, Kita T
    • Journal Title

      Biochem. Biophys. Res. Commun 331

      Pages: 1295-1300

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16590880
  • [Journal Article] Serum soluble lectin-like oxidized low-density lipoprotein receptor-1 levels are elevated in acute coronary syndrome. A novel marker for early diagnosis.2005

    • Author(s)
      Hayashida K, Kume N, Murase T, Minami M, Nakagawa D, Inada T, Tanaka M Ueda A, Kominami G, Kambara H, Kimura T, Kita T
    • Journal Title

      Circulation 112

      Pages: 812-818

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16590880
  • [Journal Article] CXCL16 is a novel angiogenic factor for human umbilical vein endothelial cells2005

    • Author(s)
      Xin, Zhuge, Toshinori, Murayama, Hidenori, Arai, Ryoko, Yamauchi, Makoto, Tanaka, Takeshi, Shimaoka, Shin, Yonehara, Noriaki, Kume, Masayuki, Yokode, Toru, Kita
    • Journal Title

      Biochem. Biophys. Res. Commun 331

      Pages: 1295-1300

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590880
  • [Journal Article] Serum soluble ectin-like oxidized low-density lipoprotein recepfor-1 levels are elevated in acute coronary syndrome. A novel marker for early diagnosis.2005

    • Author(s)
      Kazutaka Hayashida, Noriaki Kume, Takatoshi Murase T, Manabu Minami, Daisuke Nakagawa, Tsukasa Inada, Masaru Tanaka Akira Ueda, Goro Kominami, Horofumi Kambara, Takeshi Kimura, Toru Kita
    • Journal Title

      Circulation 112

      Pages: 812-818

    • Data Source
      KAKENHI-PROJECT-16590880
  • [Journal Article] CXCL16 is a novel agiogenic factor for human umbilical vein endothelial cells.2005

    • Author(s)
      Xin Zhuge, Toshinori Murayama, Hidenori Arai, Ryoko Yamauchi, Makoto Tanaka, Takeshi Shimaoka, Shin Yonehara, Noriaki Kume, Masayuki Yokode, Toru Kita
    • Journal Title

      Biochem.Biophys.Res.Commun 331

      Pages: 1295-1300

    • Data Source
      KAKENHI-PROJECT-16590880
  • [Journal Article] Apoposis of vascular cells by oxidized LDL: involvement of caspases and LOX-1, and its implication in atherosclerotic plaque rupture.2004

    • Author(s)
      Kume N, Kita T
    • Journal Title

      Circulation Research 94

      Pages: 269-270

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16590880
  • [Journal Article] Heparin-binding EGF-like growth factor induces expression of lectin-like oxidized-LDL receptor-1 in vascular smooth muscle cells.2004

    • Author(s)
      Mukai E, Kume N, et. al.
    • Journal Title

      Atherosclerosis 176

      Pages: 289-296

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16590880
  • [Journal Article] Upregulation of SR-PSOX/CXCL16 and recruitment of CD8+T cells in cardiac Valves in inflammatory valvular heart disease.2004

    • Author(s)
      Yamauchi R, Tanaka M, Kume N, et. al.
    • Journal Title

      Arteriosclerosis, Thrombosis and Vascular Biology 24

      Pages: 282-287

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16590880
  • [Journal Article] Upregulation of SR-PSOX/CXCL16 and recruitment of CD8+T cells in cardiac2004

    • Author(s)
      Yamauchi R, Tanaka M, Kume N, et al.
    • Journal Title

      Arteriosclerosis, Thrombosis and Vascular Biology 24巻

      Pages: 282-287

    • Data Source
      KAKENHI-PROJECT-16590880
  • [Journal Article] Apoposis of vascular cells by oxidized LDL : involvement of spases and LOX-1 and2004

    • Author(s)
      Kume N, Kita T
    • Journal Title

      Circulation Research 94巻

      Pages: 269-270

    • Data Source
      KAKENHI-PROJECT-16590880
  • [Journal Article] Apoposis of vascular cells by oxidized LDL : involvement of cspases and LOX-1, and its implication in atherosclerotic plaque rupture2004

    • Author(s)
      Kume, N., Kita, T
    • Journal Title

      Circulation Research 94

      Pages: 269-270

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590880
  • [Journal Article] Peroxisome proliferator-activated receptor alpha ligands activate transcription of lectin-2004

    • Author(s)
      Hayashida K, Kume N, et al.
    • Journal Title

      Biochemical Biophysical Research Communication 323巻

      Pages: 1116-1123

    • Data Source
      KAKENHI-PROJECT-16590880
  • [Journal Article] Heparin-binding EGF-like growth factor induces expression of lectin-like oxidized2004

    • Author(s)
      Mukai E, Kume N, et al.
    • Journal Title

      Ahterosclerosis 176巻

      Pages: 289-296

    • Data Source
      KAKENHI-PROJECT-16590880
  • [Journal Article] Peroxisome proliferator-activated receptor alpha ligands activate transcription of lectin-like oxidized LDL rceptor-1 gene through GC box motif2004

    • Author(s)
      Hayashida K, Kume N, et. al.
    • Journal Title

      Biochemical Biophysical Research Communication 323

      Pages: 1116-1123

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16590880
  • [Journal Article] Heparin-binding EGF-like growth factor induces expression of lectin-like oxidized LDL receptor-1 in vascular smooth muscle cells2004

    • Author(s)
      Mukai, E., Kume, N., et. al.
    • Journal Title

      Atherosclerosis 176

      Pages: 289-296

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590880
  • [Journal Article] Peroxisome proliferator-activated receptor alpha ligands activate transcription of lectin-like oxidized LDL receptor-1 through GC box motif2004

    • Author(s)
      Hayashida, K., Kume, N., et. al.
    • Journal Title

      Biochemical Biophysical Research Communication 323

      Pages: 1116-1123

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590880
  • [Journal Article] Upregulation of SR-PSOX/CXCL16 and recruitment of CD8+T cells in cardiac valves during inflammatory valvular heart disease2004

    • Author(s)
      Yamauchi, R., Tanaka, M., Kume, N., et. al.
    • Journal Title

      Arteriosclerosis, Thrombosis and Vascular Biology 24

      Pages: 282-287

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590880
  • [Presentation] Nardilysin, a new PER2-interacting protein, regulates the mammalian circadian clock2018

    • Author(s)
      Yoshinori Hiraoka, Hikari Yoshitane, Mikiko Ohno, Yusuke Morita, Rina Nunokawa, Kiyoto Nishi, Noriaki Kume, Takeshi Kimura, Yoshitaka Fukada and Eiichiro Nishi
    • Organizer
      43rd FEBS Congress
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08536
  • [Presentation] Nardilysin regulates the mammalian circadian clock via modulating PER2 function2017

    • Author(s)
      Yoshinori Hiraoka, Hikari Yoshitane, Mikiko Ohno, Yusuke Morita, Rina Nunokawa, Kiyoto Nishi, Noriaki Kume, Takeshi Kimura, Yoshitaka Fukada and Eiichiro Nishi.
    • Organizer
      European Biological Rhythms Society XV Congress
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08536
  • [Presentation] ナルディライジンによるPER2を介した概日リズム制御機構2017

    • Author(s)
      平岡義範、吉種光、大野美紀子、森田雄介、布川莉奈、西清人、久米典昭、木村剛、深田吉孝、西英一郎
    • Organizer
      第24回日本時間生物学会学術大会
    • Data Source
      KAKENHI-PROJECT-16K08536
  • [Presentation] ナルディライジンによるPER2の機能調節を介した概日リズム制御機構2017

    • Author(s)
      平岡義範、吉種光、大野美紀子、森田雄介、布川莉奈、西清人、久米典昭、木村剛、深田吉孝、西英一郎
    • Organizer
      2017年度生命科学系学会合同年次大会
    • Data Source
      KAKENHI-PROJECT-16K08536
  • [Presentation] ナルディライジンによる概日リズム制御機構の解明2016

    • Author(s)
      平岡義範、吉種光、大野美紀子、布川莉奈、西清人、森田雄介、久米典昭、木村剛、深田吉孝、西英一郎
    • Organizer
      第23回(2016年度)日本時間生物学会学術大会
    • Place of Presentation
      名古屋
    • Year and Date
      2016-11-12
    • Data Source
      KAKENHI-PROJECT-16K08536
  • [Presentation] Interleukin 18 stimulates release of soluble lectin-like oxidized LDL receptor-1 (sLOX-1)2007

    • Author(s)
      Mitsuoka H, Kume N, et. al.:
    • Organizer
      日本心臓病学会
    • Place of Presentation
      浦安市
    • Year and Date
      2007-09-11
    • Data Source
      KAKENHI-PROJECT-18590985
  • [Presentation] Lectin-like oxidized LDL receptor-1 (LOX-1) acts as a receptor for remnant-like lipoprotein particles (RLPs) and mediates RLP-induced migration of vascular smooth muscle cells2006

    • Author(s)
      Aramaki, Y., Kume, N., et. al.
    • Organizer
      ACC2006
    • Place of Presentation
      Atlanta
    • Year and Date
      2006-03-11
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590985
  • [Presentation] Lectin-like oxidized LDL receptor-1(LOX-1)acts as a receptor for remnant-like lipoprotein particles(RLPs)and mediates RLP-induced migration of vascular smooth muscle cells2006

    • Author(s)
      Aramaki Y, Kume N, et. al.:
    • Organizer
      米国心臓病学会(ACC)
    • Place of Presentation
      アトランタ(米国)
    • Year and Date
      2006-03-11
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590985
  • 1.  YOKODE Masayuki (20252447)
    # of Collaborated Projects: 13 results
    # of Collaborated Products: 0 results
  • 2.  KITA Toru (60161460)
    # of Collaborated Projects: 11 results
    # of Collaborated Products: 0 results
  • 3.  ISHII Kenji (00212811)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 4.  DOI Toshio (60183498)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 5.  ARAI Hidenori (60232021)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 6.  WAKATSUKI Yoshio (40220826)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 7.  HORIUCHI Hisanori (90291426)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 8.  UEDA Yukihiko (70252434)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 9.  TANAKA Makoto (00271007)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 10.  HIRAOKA Yoshinori (60397552)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 7 results
  • 11.  OCHI Hiroshi (80204220)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 12.  CHAIT Alan
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 13.  GIMBRONE Mic
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 14.  TOYOYHARA Masako (50241211)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  MURAKAMI Motonobu (10157761)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  MURAKAMI Takashi (40210009)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  MIZUNO Akira (80219641)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  KUWAJIMA Masamichi (00205262)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  HASHIMOTO Nobuo (40135570)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  NOZAKI Kazuhiko (90252452)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  NAGATA Kazuhiro (50127114)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  HASEGAWA Koji (50283594)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  SAJI Hideo (40115853)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 24.  KUGE Yuji (70321958)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 25.  TADAMURA Eiji (70303831)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  NOHARA Ryuji (80180769)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 27.  MUKAI Takahiro (30284706)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 28.  Yoshida Kazumichi (90598921)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  家原 典之 (20281727)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  袴田 康弘 (30261233)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  吉岡 秀幸 (30231690)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  西 英一郎 (30362528)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 8 results
  • 33.  HAMAGUTHI Hiroshi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 34.  Okada Tomohisa
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 35.  Matsumoto Masayasu
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 36.  Iihara Koji
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 37.  Okada Yasushi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 38.  Toyoda Kazunori
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 39.  Takahashi Jun
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 40.  GIMBRONE Michael A.jr.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 41.  MICHAEL A. G
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 42.  ALAN Chait
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 43.  CYBULSKI Myr
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 44.  GIMBRONE Jr
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 45.  CYBULSKY Myron I
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 46.  GIMBRONE Michael A.Jr
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 47.  CYBULSKY Myr
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 48.  HORIE Takahiro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 49.  KUWABARA Yasuhide
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 50.  KIMURA Takeshi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 51.  矢作 直也
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 52.  尾野 亘
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 53.  中邨 智之
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 54.  島野 仁
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results

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