HAYASHI Hideki 林日出喜

Researcher Number	10218589
Other IDs
External Links
Affiliation (Current)	2025: 長崎大学, 先端創薬イノベーションセンター, 特任研究員
Affiliation (based on the past Project Information) *help	2025: 長崎大学, 先端創薬イノベーションセンター, 特任研究員 2016 – 2018: 長崎大学, 医歯薬学総合研究科(医学系), 准教授 2014: 長崎大学, 医歯薬学総合研究科(医学系), 准教授 2013: 長崎大学, 大学院医歯薬学総合研究科, 准教授 2012 – 2013: 長崎大学, 医歯(薬)学総合研究科, 准教授 … More 2012: 長崎大学, 医歯薬学総合研究科, 准教授 2011: 長崎大学, 大学院・医歯薬学総合研究科, 准教授 2010: 長崎大学, 医歯薬学総合研究科, 准教授 2004 – 2005: 長崎大学, 大学院・医歯薬学総合研究科, 講師 2002 – 2003: 長崎大学, 大学院・医歯薬学総合研究科, 助手 1998: 徳島大, 助教授 1997: The University of Tokushima, Institute for Enzyme Research, Associate Professor, 分子酵素学研究センター, 助教授 1994 – 1996: 徳島大学, 酵素科学研究センター, 助教授 1990 – 1993: The University of Tokushima Institute for Enzyme Research Research Associate, 酵素科学研究センター, 助手 Less
Review Section/Research Field	Principal Investigator General medical chemistry / Basic Section 49010:Pathological biochemistry-related / Applied pharmacology / 細胞死(アポトーシス) / Virology Except Principal Investigator Pathological medical chemistry / General pharmacology / Functional biochemistry / General medical chemistry / Virology / Morphological basic dentistry / Structural biochemistry
Keywords	Principal Investigator PI3-キナーゼ / グルコース取り込み / インスリン / サイトカイン検出 / T細胞機能 / インターフェロンシグナル / バイオテクノロジー / ウィルス / ゲノム / 癌 … More / 遺伝子 / 遺伝子増幅 / レンチウイルスベクター / アデノ随伴ウイルスベクター / レンチウイルス / 自己削除型ベクター / 「自己削除型」レンチウイルスベクター / 遺伝子ノックアウト / 遺伝子治療 / CRISPR/Cas9 / AAV(アデノ随伴ウイルスベクター)ベクター / 自己削除型レンチウイルスベクター / ゲノム編集 / apoptosis / caspase / cytochrome c / アポトーシス / カスパーゼ / チトクロームc / A型インフルエンザウイルス / インターフェロン誘導遺伝子ISGs / A型インフルエンザ・ウイルス / トリプシノーゲン遺伝子 / インターフェロン調節因子IRFs / インターフェロン調節因子 / インターフェロン誘導遺伝子 / インターフェロン誘導遺伝子(ISGs) / インターフェロン調節因子(IRFs) / エンテロキナーゼ / トリプシノーゲン / インフルエンザウイルス / グルコーストランスポーター / インスリン作用 / トランスロケーション / GLUT4 / 糖尿病 / シグナル伝達 / グルコーストランスポータータイプ4 / インスリンシグナル伝達 / PI-3キナーゼ … More Except Principal Investigator 糖尿病 / インスリン / グルコーストランスポーター / トランスロケーション / シグナル伝達 / グルコース取り込み / PI3-キナーゼ / トランスジェニックマウス / インスリンレセプタ- / Insulin signal transduction / GLUT4 / インスリンレセプター / インスリンシグナル伝達 / 遺伝子工学 / PIー3キナ-ゼ / Insulin Receptor / インスリンレセプタ-遺伝子異常 / 三量体Gタンパク / インスリン作用 / グルコ-ストランスポ-タ- / 異常インスリンレセプタ- / ヒトインスリンレセプタ- / 機能材料 / チロシンキナ-ゼ / Confocal laser microscope / RT-PCR method / Movement in digestive tube / GABA-B2 subunit / GABA-B1 subtype / GABA-B1 subunit / Two hetero amount body / GABA_B receptor / 共焦点レーザー顕微鏡 / 共焦点レーザ顕微鏡 / RT-PCR法 / 消化管運動 / GABA-B2サブユニット / GABA-B1サブタイプ / GABA-B1サブユニット / ヘテロ2量体 / GABA-B受容体 / glucose transporter / drug for diabetes / 非アイソトープ測定 / GLUT4トランスロケーション / 糖尿病薬 / Diabetes / glucosetransporter / Insulin action / G-proteins / GLUT4 translocation / PI3-kinase / GTP結合タンパク質 / 細胞増殖因子 / PI 3-キナーゼ / PI 3-kinase / PI-3キナーゼ / Mutation / NIDDM / 遺伝子診断 / Gene expression / Insulin receptor / Sp1 / 遺伝子発現 / RNaseL / ウイルス高感受性細胞 / インターフェロン誘導遺伝子 / ワクチン / iPS細胞 / IRF / インターフェロン / ウイルス / 転写因子 / 軟骨細胞 / 骨格形成 / Tcf7 / Wnt / FGF / クロマチン修飾 / Mef2 / Dlx5 / 間葉系幹細胞 / 転写制御 / 骨芽細胞 / エンハンサー / Runx2 / ノルアドレナリン / 三量体Cタンパク / グルコストランスポータータイプ4 / 高次構造 / Gタンパク / エキソサイトーシス / GTP結合蛋白質 / PCR / インスリンレセプター異常 / インスリンセプター異常 / 異常インスリンレセプター / ヒトインスリンレセプター / 機能性材料 / インスリンレセプタ-異常 / タンパク質の局在化 / 細胞増殖 / エンハンサ- / グルコ-ストランスポ-タ-タイプI Less

Regulation of T Cell Function Using a Newly-Developed IFNAR Signaling SystemPrincipal Investigator
- Principal Investigator
  
  林日出喜
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Nagasaki University
Development of gene therapy using self-destructive lentivirus vectorsPrincipal Investigator
- Principal Investigator
  
  HAYASHI Hideki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Applied pharmacology
- Research Institution
  Nagasaki University
Defensive mechanism of interferon-regulatory factors (IRFs) via trypsinogens against virus infection.Principal Investigator
- Principal Investigator
  
  HAYASHI Hideki
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  Nagasaki University
The mechanism of transcriptional regulation of Runx2 gene and the program of skeletal development
- Principal Investigator
  
  KOMORI Toshihisa
- Project Period (FY)
  2010 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Nagasaki University
Establishment of an interferon transfer factor prevention cell strainuseful on virus hunting
- Principal Investigator
  
  MATSUYAMA Toshifumi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Virology
- Research Institution
  Nagasaki University
Analysis of body GABAB receptor of two hetero amounts that makes creation of improvement of movement in digestive tube medicine target
- Principal Investigator
  
  TANIYAMA Kohtaro
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Nagasaki University
Cloning of molecules that activate caspase9 regardless of cytochrome c.Principal Investigator
- Principal Investigator
  
  HAYASHI Hideki
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  細胞死(アポトーシス)
- Research Institution
  Nagasaki University
インスリンによるグルコース細胞内輸送促進の分子メカニズムPrincipal Investigator
- Principal Investigator
  
  林日出喜
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  The University of Tokushima
グルコーストランスポーターの構造・機能相関
- Principal Investigator
  
  蛯名洋介
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokushima
インスリンによるグスコース細胞内輸送促進の分子メカニズムPrincipal Investigator
- Principal Investigator
  
  林日出喜
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  The University of Tokushima
myc-tagを用いたインスリン反応性グリコーストランスポーターの構造と機能解析
- Principal Investigator
  
  蛯名洋介
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Structural biochemistry
- Research Institution
  The University of Tokushima
Molecular mechanisms of insulin signal transduction and diabetes mellitus
- Principal Investigator
  
  EBINA Yousuke
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  The University of Tokushima
Development of a simple screening system for the discovery of a new drug for diabetes
- Principal Investigator
  
  EBINA Yousuke
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Functional biochemistry
- Research Institution
  The University of Tokushima
インスリン作用とGTP結合蛋白質
- Principal Investigator
  
  蛯名洋介
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokushima
インスリンシグナル伝達における蛋白質高次構造認識機構
- Principal Investigator
  
  蛯名洋介
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokushima
グルコーストランスポーターの細胞内局在変化の分子メカニズムとインスリン作用
- Principal Investigator
  
  蛯名洋介
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokushima
インスリン作用とGTP結合蛋白質
- Principal Investigator
  
  蛯名洋介
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokushima
インスリンシグナル伝達における蛋白質高次構造認識機構
- Principal Investigator
  
  蛯名洋介
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokushima
インスリンによる細胞内のグルコース取り込み促進の分子メカニズムの解明Principal Investigator
- Principal Investigator
  
  林日出喜
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  The University of Tokushima
Molecular mechanisms of insulin signal transduction and diabetes mellitus
- Principal Investigator
  
  EBINA Yousuke
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  The University of Tokushima
グルコーストランスポーターの細胞内局在変化の分子メカニズムとインスリン作用
- Principal Investigator
  
  蛯名洋介
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokushima
インスリンレセプター遺伝子異常と糖尿病
- Principal Investigator
  
  蛯名洋介
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokushima
インスリン作用とGTP結合蛋白質
- Principal Investigator
  
  蛯名洋介
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokushima
インスリンシグナル伝達におけるフォスファチジル・イノシトール-3キナーゼの役割Principal Investigator
- Principal Investigator
  
  林日出喜
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  The University of Tokushima
生体受容体を機能性材料として開発するための基礎的研究
- Principal Investigator
  
  蛯名洋介
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokushima
ヒト異常インスリン受容体遺伝子導入による糖尿病モデルマウスの作製
- Principal Investigator
  
  蛯名洋介
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokushima
インスリンレセプター遺伝子異常と糖尿病
- Principal Investigator
  
  蛯名洋介
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokushima
生体受容体を機能材料として開発するための基礎的研究
- Principal Investigator
  
  蝦名洋介
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokushima
ヒト異常インスリン受容体遺伝子導入による糖尿病モデルマウスの作製
- Principal Investigator
  
  蝦名洋介
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokushima
インスリン刺激によるグルコ-ストランスポ-タ-の細胞内局在変化の分子メカニズム
- Principal Investigator
  
  蛯名洋介
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokushima
インスリンレセプタ-遺伝子異常と糖尿病
- Principal Investigator
  
  蛯名洋介
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokushima
Molecular mechanisms of insulin signal transduction and its disorder
- Principal Investigator
  
  EBINA Yousuke
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  The University of Tokushima
細胞増殖シグナルによるグルコ-ストランスポ-タ-動的変化の分子機構
- Principal Investigator
  
  EBINA Yousuke
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  The University of Tokushima
生体受容体を機能材料として開発するための基礎的研究
- Principal Investigator
  
  蛯名洋介
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokushima
ヒト異常インスリン受容体遺伝子導入による糖尿病モデルマウスの作製
- Principal Investigator
  
  蛯名洋介
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokushima
Establishment of a simple diagnostic method for the detection of mutations of insulin receptor gene in Non-Insulin Dependent Diabetes Mellitus
- Principal Investigator
  
  EBINA Yousuke
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  The University of Tokushima
Structure and Function of Insulin Receptor, its Gene Expression and its Signal Transduction Mechanism
- Principal Investigator
  
  EBINA Yousuke
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  The University of Tokushima

All 2019 2018 2017 2014 2013 2012 2011 2010 2004 Other

All Journal Article Presentation Patent

[Journal Article] Cytoplasmic R-peptide of murine leukemia virus envelope protein negatively regulates its interaction with the cell surface receptor2019
- Author(s)
  Kubo Yoshinao、Izumida Mai、Togawa Kei、Zhang Fengmin、Hayashi Hideki
- Journal Title
  
  Virology
  
  Volume: 532 Pages: 82-87
- DOI
  10.1016/j.virol.2019.04.005
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15319
[Journal Article] Enterokinase Enhances Influenza A Virus Infection by Activating Trypsinogen in Human Cell Lines.2018
- Author(s)
  Hayashi H, Kubo Y, Izumida M, Takahashi E, Kido H, Sato K, Yamaya M, Nishimura H, Nakayama K, Matsuyama T.
- Journal Title
  
  Front Cell Infect Microbiol
  
  Volume: 8 Pages: 91-91
- DOI
  10.3389/fcimb.2018.00091
- NAID
  120006937672
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K15319, KAKENHI-PROJECT-16H05348, KAKENHI-PROJECT-15K08499
[Journal Article] Role of Ezrin Phosphorylation in HIV-1 Replication2018
- Author(s)
  Kamiyama Haruka、Izumida Mai、Umemura Yuria、Hayashi Hideki、Matsuyama Toshifumi、Kubo Yoshinao
- Journal Title
  
  Frontiers in Microbiology
  
  Volume: 9
- DOI
  10.3389/fmicb.2018.01912
- NAID
  120006987949
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K15319
[Journal Article] MicroRNA-3662 expression correlates with antiviral drug resistance in adult T-cell leukemia/lymphoma cells.2018
- Author(s)
  Yasui K, Izumida M, Nakagawa T, Kubo Y, Hayashi H, Ito T, Ikeda H, Matsuyama T
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 印刷中 Issue: 4 Pages: 833-837
- DOI
  10.1016/j.bbrc.2018.04.159
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K15319, KAKENHI-PROJECT-17H04044, KAKENHI-PROJECT-17K07287, KAKENHI-PROJECT-18K19584, KAKENHI-PROJECT-18H02872
[Journal Article] Rab3a-Bound CD63 Is Degraded and Rab3a-Free CD63 Is Incorporated into HIV-1 Particles.2017
- Author(s)
  Kubo Y, Masumoto H, Izumida M, Kakoki K, Hayashi H, Matsuyama T
- Journal Title
  
  Front Microbiol
  
  Volume: 29 Pages: 1653-1653
- DOI
  10.3389/fmicb.2017.01653
- NAID
  120006987411
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K15319, KAKENHI-PROJECT-15K08499
[Journal Article] SAM domain-containing N-terminal region of SAMHD1 plays a crucial role in its stabilization and restriction of HIV-1 infection2014
- Author(s)
  Shigematsu S, Hayashi H, Yasui K, Matsuyama T.
- Journal Title
  
  Acta Med Nagasaki
  
  Volume: 58 Pages: 103-111
- NAID
  130004879524
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24590555
[Journal Article] Susceptibility of muridae cell lines to ecotropic murine leukemia virus and the cationic amino acid transporter 1 viral receptor sequences: implications for evolution of the viral receptor.2014
- Author(s)
  Kakoki K, Shinohara A, Izumida M, Koizumi Y, Honda E, Kato G, Igawa T, Sakai H, Hayashi H, Matsuyama T, Morita T, Koshimoto C, Kubo Y.
- Journal Title
  
  Virus Genes.
  
  Volume: 48 Issue: 3 Pages: 448-456
- DOI
  10.1007/s11262-014-1036-1
- NAID
  120006986554
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24590555, KAKENHI-PROJECT-26292170
[Journal Article] Androgen-independent proliferation of LNCaP prostate cancer cells infected by xenotropic murine leukemia virus-related virus.2014
- Author(s)
  Kakoki K, Kamiyama H, Izumida M, Yashima Y, Hayashi H, Yamamoto N, Matsuyama　T, Igawa T, Sakai H, Kubo Y.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 447 Issue: 1 Pages: 216-222
- DOI
  10.1016/j.bbrc.2014.03.154
- NAID
  120006986603
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24590555
[Journal Article] A short variant BTBD2 as a novel negative regulator of IRF-associated signalling.2013
- Author(s)
  Chua KJ, Kubo Y, Ma Y, Yasui K, Matsuyama T, and Hayashi H.
- Journal Title
  
  Int J Integrative Biol
  
  Volume: 14 Pages: 3138-3138
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590555
[Journal Article] CXCR4-tropic, but not CCR5-tropic, human immunodeficiency virus infection is inhibited by the lipid raft-associated factors, acyclic retinoid analogs, and cholera toxin B subunit2013
- Author(s)
  H. Kamiyama, K. Kakoki, S. Shigematsu, M. Izumida, Y. Yashima, Y. Tanaka, H. Hayashi, T. Matsuyama, H. Sato, N. Yamamoto, T. Sano, Y. Shidoji, Y. Kubo
- Journal Title
  
  AIDS Res.Hum.Retrovir.
  
  Volume: 29 Issue: 2 Pages: 279-88
- DOI
  10.1089/aid.2012.0174
- NAID
  120006985740
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590416, KAKENHI-PROJECT-22659092, KAKENHI-PROJECT-23617020, KAKENHI-PROJECT-24590555
[Journal Article] Serum starvation activates NF-kB through G protein B2 subunit-mediated signal2012
- Author(s)
  T. Kohno, Y. Kubo, K. Yasui, M. Haraguchi, S. Shigematsu, K.J. Chua, T. Matsuyama, H. Hayashi.
- Journal Title
  
  DNA Cell Biol
  
  Volume: 31 Issue: 11 Pages: 1636-44
- DOI
  10.1089/dna.2012.1666
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590416, KAKENHI-PROJECT-22659092, KAKENHI-PROJECT-24590555
[Journal Article] Serum Starvation Activates NF-κB Through G Protein β2 Subunit-Mediated Signal2012
- Author(s)
  Kohno T, Kubo Y, Yasui K, Haraguchi M, Shigematsu S, Chua KJ, Matsuyama T, Hayashi H
- Journal Title
  
  DNA Cell Biol
  
  Volume: 31(11) Pages: 1636-44
- NAID
  120006985903
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659092
[Journal Article] Retrovirus entry by endocytosis and cathepsinproteases.2012
- Author(s)
  Y. Kubo, H. Hayshi, T. Matsuyama, H. Sato, N. Yamamoto.
- Journal Title
  
  Adv.Virol.
  
  Volume: 2012 Pages: 640894-640894
- DOI
  10.1155/2012/640894
- NAID
  120006985742
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590416, KAKENHI-PROJECT-24590555
[Journal Article] Infection of XC cells by MLVs and Ebola virus is endosome-dependent but acidification-independent2011
- Author(s)
  Kamiyama H, Kakoki K, Yoshii H, Iwao M, Igawa T, Sakai H, Hayashi H, Matsuyama T, Yamamoto N, Kubo Y.
- Journal Title
  
  PLoS One
  
  Volume: 6(10)
- NAID
  120006985272
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659092
[Journal Article] CD4-independent humanimmunodeficiency virus infection involves participation of endocytosis and cathepsin B2011
- Author(s)
  Yoshii H, Kamiyama H, Goto K, Oishi K, Katunuma N, Tanaka Y, Hayashi H, Matsuyama T, Sato H, Yamamoto N, Kubo Y
- Journal Title
  
  PLoS One
  
  Volume: 6(4)
- NAID
  120006985096
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659092
[Journal Article] Interferon regulatory factor-4 activates IL-2 and IL-4 promoters in cooperation with c-Rel2011
- Author(s)
  H. Shindo, K. Yasui, K. Yamamoto, K. Honma, K. Yui, T. Kohno, Y. Ma, K.J. Chua, Y. Kubo, H. Aihara, T. Ito, T.Nagayasu, T. Matsuyama, H. Hayashi.
- Journal Title
  
  Cytokine
  
  Volume: 56 Issue: 3 Pages: 564-72
- DOI
  10.1016/j.cyto.2011.08.014
- NAID
  120006985203
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590416, KAKENHI-PROJECT-22659092, KAKENHI-PUBLICLY-23131510
[Journal Article] Characterization of dsRNA-induced pancreatitis model reveals the regulatory role of IRF-2 intrypsinogen5 gene transcription2011
- Author(s)
  Hideki Hayashi
- Journal Title
  
  Proc Natl Acad Sci USA
  
  Volume: 108 Pages: 18766-71
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659092
[Journal Article] Characterization of dsRNA-induced pancreatitis model reveals the regulatory role of IRF-2 in trypsinogen5 gene transcription2011
- Author(s)
  Hayashi H, Kohno T, Yasui K, Murota H, Kimura T, Duncan GS, Nakashima T, Yamamoto K, Katayama I, Ma Y, Chua KJ, Suematsu T, Shimokawa I, Akira S, Kubo Y, Mak TW, Matsuyama T
- Journal Title
  
  Proc Natl Acad Sci U S A
  
  Volume: 108(46) Pages: 18766-71
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659092
[Journal Article] Aberrant expression of interferon regulatory factor 3 in human lung cancer.2010
- Author(s)
  Tokunaga T, Naruke Y, Shigematsu S, Kohno T, Yasui K, Ma Y, Chua KJ, Katayama I, Nakamura T, Hishikawa Y, Koji T, Yatabe Y, Nagayasu T, Fujita T,Matsuyama T, Hayashi H
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 397(2) Pages: 202-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659092
[Journal Article] Characterization of GABA_B Receptor in the Human Colon.2004
- Author(s)
  Uesono Y, Kaibara M, Hayashi H, Kawakami S, Enjoji A, Kanematsu T, Taniyama K
- Journal Title
  
  Journal of Pharmacological Sciences 94
  
  Pages: 211-213
- NAID
  130000073876
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590200
[Patent] ウイルス感染症の予防又は治療剤2012
- Inventor(s)
  久保嘉直、神山陽香、鹿子木桂、松山俊文、林日出喜
- Industrial Property Rights Holder
  久保嘉直、神山陽香、鹿子木桂、松山俊文、林日出喜
- Industrial Property Rights Type
  特許
- Filing Date
  2012-10-30
- Overseas
- Data Source
  KAKENHI-PROJECT-22659092
[Patent] ウイルス感染症の予防又は治療剤2012
- Inventor(s)
  久保嘉直、神山陽香、鹿子木桂、松山俊文、林日出喜
- Industrial Property Rights Holder
  国立大学法人長崎大学
- Filing Date
  2012-10-30
- Overseas
- Data Source
  KAKENHI-PROJECT-22659092
[Presentation] カテプシンBはチクングニヤウイルスのエンベロープ蛋白質を介した感染に必須である2018
- Author(s)
  Mai Izumida，Yoshinao Kubo，Hideki Hayashi，Atsushi Tanaka
- Organizer
  第66回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-16K15319
[Presentation] インターフェロンG誘導遺伝子GILTによるHIV粒子産物抑制機構の解明2013
- Author(s)
  久保嘉直、神山陽香、泉田真生、田中勇悦、安井潔、佐藤祐徳、山本直樹、松山俊文、林日出喜
- Organizer
  第61回日本ウイルス学会学術総会
- Place of Presentation
  神戸国際会議場 (神戸市中央区)
- Data Source
  KAKENHI-PROJECT-24590555
[Presentation] ATL細胞株の細胞死をTRAIL-依存性に促進させる生物活性物質のスクリーニング2012
- Author(s)
  林日出喜、長谷川寛雄、河野友子、中尾一彦、松山俊文
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24590555
[Presentation] 血清枯渇はG Protein β2を介したNF-κB経路を活性化する2012
- Author(s)
  安井潔, 河野友子、久保嘉直、原口恵、重松小百合、蔡君柔、松山俊文、林日出喜
- Organizer
  第35回日本分子生物学会
- Place of Presentation
  マリンメッセ福岡
- Data Source
  KAKENHI-PROJECT-24590555
[Presentation] Screening of bioactive products to induce TRAIL-dependent cell death in ATL cells -ATL細胞株の細胞死をTRAIL-依存性に促進させる生物活性物質のスクリーニング2012
- Author(s)
  林日出喜
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22659092
[Presentation] Identification of poly(I:C)-induced pancreatitis- related genes in IRF2-deficient mice2012
- Author(s)
  Hayashi H
- Organizer
  3rd International conference on“Current advances in Microbiology and Immunology”
- Place of Presentation
  ULAANBAATAR, MONGOLIA
- Invited
- Data Source
  KAKENHI-PROJECT-24590555
[Presentation] Identification of poly(I:C)-induced pancreatitis-related genes in IRF2-deficient mice2011
- Author(s)
  林日出喜
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22659092
[Presentation] インターフェロンによるレトロウイルス感染抑制に関与する新規細胞性因子の同定
- Author(s)
  久保嘉直、泉田真生、安井潔、林日出喜、松山俊文
- Organizer
  第62回日本ウイルス学会学術総会
- Place of Presentation
  パシフィコ横浜(横浜市)
- Year and Date
  2014-11-10 – 2014-11-12
- Data Source
  KAKENHI-PROJECT-24590555

1. EBINA Yousuke (00112227)

# of Collaborated Projects: 26 results

# of Collaborated Products: 0 results
2. MURAKAMI Takashi (40210009)

# of Collaborated Projects: 22 results

# of Collaborated Products: 0 results
3. KISHI Kazuhiro (70284320)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
4. MATSUYAMA Toshifumi (30165922)

# of Collaborated Projects: 2 results

# of Collaborated Products: 13 results
5. KUBO Yoshinao (30273527)

# of Collaborated Projects: 2 results

# of Collaborated Products: 16 results
6. KOMORI Toshihisa (00252677)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. MASUYAMA Ritsuko (60297596)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. MIYAZAKI Toshihiro (10174161)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. MORIISHI Takeshi (20380983)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. TANIYAMA Kohtaro (70030898)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. UEZONO Yasuhito (20213340)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 伊藤公成 (00332726)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 貝原宗重 (40274633)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
14. 長谷川寛雄 (00398166)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 田中義正 (90280700)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. MATSUOKA Yukio

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. ASAHI Yoshihiko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. NAKAO Kazuhiko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

HAYASHI Hideki 林 日出喜

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Regulation of T Cell Function Using a Newly-Developed IFNAR Signaling SystemPrincipal Investigator

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Development of gene therapy using self-destructive lentivirus vectorsPrincipal Investigator

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Defensive mechanism of interferon-regulatory factors (IRFs) via trypsinogens against virus infection.Principal Investigator

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Cloning of molecules that activate caspase9 regardless of cytochrome c.Principal Investigator

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インスリンによるグルコース細胞内輸送促進の分子メカニズムPrincipal Investigator

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インスリンによるグスコース細胞内輸送促進の分子メカニズムPrincipal Investigator

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HAYASHI Hideki 林日出喜