Tanaka Teruyuki 田中輝幸

… Alternative Names

TANAKA Teruyuki 田中輝幸

田中輝幸タナカテルユキ

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Researcher Number	10246647
Other IDs
Affiliation (Current)	2025: 東京大学, 大学院医学系研究科(医学部), 客員研究員
Affiliation (based on the past Project Information) *help	2023: 東京大学, 大学院医学系研究科(医学部), 客員研究員 2016 – 2022: 東京大学, 大学院医学系研究科(医学部), 准教授 2015: 東京大学, 医学(系)研究科(研究院), 准教授 2011 – 2013: 東京大学, 医学(系)研究科(研究院), 准教授 2009 – 2010: The University of Tokyo, 大学院・医学系研究科, 准教授 2007: 東京大学, 大学院・医学系研究科, 准教授
Review Section/Research Field	Principal Investigator Pediatrics / Basic Section 51030:Pathophysiologic neuroscience-related / Basic Section 52050:Embryonic medicine and pediatrics-related / Neuroscience in general Except Principal Investigator Basic Section 52050:Embryonic medicine and pediatrics-related / Hygiene
Keywords	Principal Investigator てんかん / 発達障害 / CDKL5 / キナーゼ / ノックアウトマウス / レット症候群 / 海馬 / シナプス / 神経回路 / 活動依存性マンガン造影MRI … More / CDKL3 / 神経発達障害 / アデノ随伴ウイルスベクター / ノックインマウス / アデノ随伴ウイルス / 遺伝子治療 / 精神運動発達遅滞 / けいれん / GluN2B / NMDA受容体 / 記憶障害 / 情動障害 / 相互作用 / リン酸化 / 行動解析 / 遺伝子改変マウス / プロテオーム / プロテオーム解析 / 遺伝子 / 神経科学 / 脳神経疾患 … More Except Principal Investigator 漢方薬 / レット症候群 / 細胞内情報伝達 / 神経分化 / cdkl5ノックアウトマウス / Cdkl5ノックアウトマウス / 神経分化誘導作用 / 一味抜き成分 / 抑肝散 / CDKL5 / 受容体 / 神経伝達物質 / 有機溶剤 / フロン代替 / 遺伝子発現 / 海馬 / 感受性 / 中枢神経毒性 / 分子標的 / フロン代替物質 / バイオマーカー / 神経毒性 / ブロモプロパン Less

Molecular and neurocircuit mechanisms of excitatory/inhibitory imbalance and developmental disorders caused by CDKL5 kinase activity deficiencyPrincipal Investigator
- Principal Investigator
  
  田中輝幸
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  The University of Tokyo
Creation of therapeutic agent for Rett syndrome (CDKL5 deficiency disorder) using Kampo medicine
- Principal Investigator
  
  Inazu Tetsuya
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Ritsumeikan University
Pathomechanisms of developmental epileptic encephalopathy caused by CDKL5/CDKL3 mutations and development of the gene therapyPrincipal Investigator
- Principal Investigator
  
  Tanaka Teruyuki
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  The University of Tokyo
Elucidating synaptic mechanisms and treatment of epileptic encephalopathy associated with CDKL5 mutationsPrincipal Investigator
- Principal Investigator
  
  TANAKA Teruyuki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  The University of Tokyo
Multidimensional analyses of the CDKL5, a causative gene for neurodevelopment disorders, by proteomic and LOF approachesPrincipal Investigator
- Principal Investigator
  
  Tanaka Teruyuki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neuroscience in general
- Research Institution
  The University of Tokyo
難治性てんかん・非定型レット症候群の原因遺伝子欠損マウス作製・解析と分子標的解明Principal Investigator
- Principal Investigator
  
  田中輝幸
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Pediatrics
- Research Institution
  The University of Tokyo
Analysis of molecular and cellular targets in neurotoxicity of alternatives to ozone-depleting substances and establishment of biomarkers for the central nervous toxicity
- Principal Investigator
  
  ICHIHARA Gaku
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hygiene
- Research Institution
  Nagoya University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2013 2012 2011 2010 2009

All Journal Article Presentation

[Journal Article] Effect of active vitamin D treatment on development of type 2 diabetes: DPVD randomised controlled trial in Japanese population2022
- Author(s)
  Tetsuya Kawahara, Gen Suzuki, Shoichi Mizuno, Tetsuya Inazu, Fumiyoshi Kasagi, Chie Kawahara, Yosuke Okada, Yoshiya Tanaka
- Journal Title
  
  BMJ
  
  Volume: 377 Pages: e066222-e066222
- DOI
  10.1136/bmj-2021-066222
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08264
[Journal Article] 発達障害の生物学的背景2019
- Author(s)
  田中輝幸
- Journal Title
  
  Modern Physician
  
  Volume: 39 Pages: 1106-1108
- Data Source
  KAKENHI-PROJECT-18K07784
[Journal Article] Comprehensive behavioral analysis of the Cdkl5 knockout mice revealed significant enhancement in anxiety- and fear-related behaviors and impairment in both acquisition and long-term retention of spatial reference memory2018
- Author(s)
  Okuda Kosuke、Takao Keizo、Watanabe Aya、Miyakawa Tsuyoshi、Mizuguchi Masashi、Tanaka Teruyuki
- Journal Title
  
  PLOS ONE
  
  Volume: 13 Issue: 4 Pages: e0196587-e0196587
- DOI
  10.1371/journal.pone.0196587
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09614, KAKENHI-PROJECT-18K07784, KAKENHI-PROJECT-18H05213, KAKENHI-PUBLICLY-17H06051, KAKENHI-PROJECT-16K01946
[Journal Article] CDKL5 controls postsynaptic localization of GluN2B-containing NMDA receptors in the hippocampus and regulates seizure susceptibility.2017
- Author(s)
  Okuda K, Kobayashi S, Fukaya M, Watanabe A, Murakami T, Hagiwara M, Sato T, Ueno H, Ogonuki N, Komano-Inoue S, Manabe H, Yamaguchi M, Ogura A, Asahara H, Sakagami H, Mizuguchi M, Manabe T, Tanaka T
- Journal Title
  
  Neurobiology of Diseases
  
  Volume: 106 Pages: 158-170
- DOI
  10.1016/j.nbd.2017.07.002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-16H01266, KAKENHI-PROJECT-15H04672, KAKENHI-PROJECT-15K09614
[Journal Article] Towards elucidating the regulatory roles of <i>CDKL5</i> in synaptic transmission2015
- Author(s)
  奥田耕助、田中輝幸
- Journal Title
  
  Folia Pharmacologica Japonica
  
  Volume: 145 Issue: 4 Pages: 183-186
- DOI
  10.1254/fpj.145.183
- NAID
  130005061553
- ISSN
  0015-5691, 1347-8397
- Language
  Japanese
- Data Source
  KAKENHI-PROJECT-15K09614
[Journal Article] 小児の難治性てんかんとCDKL52013
- Author(s)
  田中輝幸、奥田耕助
- Journal Title
  
  Clinical Neuroscience
  
  Volume: 31 Pages: 699-702
- Data Source
  KAKENHI-PROJECT-23500381
[Presentation] CDKL5機能喪失による発達性てんかん脳症 (CDKL5 欠損症) のマクロ・ミクロ・メゾスコピックスケール解析による病態機序の解明2023
- Author(s)
  田中輝幸
- Organizer
  第93回大阪小児神経学懇話会
- Invited
- Data Source
  KAKENHI-PROJECT-23K06803
[Presentation] Brain-wide identification of altered functional connectivity and neuronal activity in CDKL5 kinase-dead knock-in mice2023
- Author(s)
  Teruyuki Tanaka, Toshiki Nomura, Tomonari Murakami, Kumiko Saitou, Yuji Komaki, Makoto Osanai, Kenichi Ohki
- Organizer
  The 65th Annual Meeting of the Japanese Society of Child Neurology
- Data Source
  KAKENHI-PROJECT-23K06803
[Presentation] Identification of altered functional connectivity and neural activity in whole brain upon the loss of CDKL5 kinase activity in Cdkl5 kinase-dead knock-in mice2023
- Author(s)
  Teruyuki Tanaka
- Organizer
  2023 CDKL5 Workshop in Asia
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K06803
[Presentation] Multimodal analysis of intrinsic activity, connectivity, and neural timescales in the CDKL5 mutant mouse brain2023
- Author(s)
  Teruyuki Tanaka
- Organizer
  2023 CDKL5 Forum
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K06803
[Presentation] In vivo wide-field Ca2+ imaging of the cortical spontaneous activity in the Cdkl5 mutant mice reveals altered functional connectivity upon the loss-of-function of CDKL52021
- Author(s)
  Teruyuki Tanaka, Toshiki Nomura, Tomonari Murakami, Kumiko Saitou, Kenichi Ohki
- Organizer
  Society for Neuroscience Global Connectome 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07784
[Presentation] In vivo大脳皮質広域カルシウムイメージングによる CDKL5機能欠損マウス脳における機能的結合性の変化の同定2020
- Author(s)
  田中輝幸、野村俊貴、村上知成、斉藤久美子、大木研一
- Organizer
  第50回日本神経精神薬理学会年会・42回日本生物学的精神医学会年会・第4回日本精神薬学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-18K07784
[Presentation] Assessing functional connectivity in the brain upon the loss of CDKL5 by the in vivo wide-field Ca2+ imaging of cerebral cortices of the Cdkl5 mutant mice, and by the resting-state fMRI analysis of CDD patients2020
- Author(s)
  Teruyuki Tanaka, Toshiki Nomura
- Organizer
  2020 CDKL5 Forum
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07784
[Presentation] In vivo wide-field Ca2+ imaging of the cortical spontaneous activity in the Cdkl5 mutant mice reveals altered functional connectivity upon the loss-of-function of CDKL52020
- Author(s)
  Toshiki Nomura, Tomonari Murakami, Kumiko Saitou, Kenichi Ohki, Teruyuki Tanaka
- Organizer
  第43回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-18K07784
[Presentation] Evaluating the cortical functional connectivity in Cdkl5 mutant mice by in vivo wide-field Ca2+ imaging2020
- Author(s)
  Teruyuki Tanaka, Toshiki Nomura, Tomonari Murakami, Kumiko Saitou, Kenichi Ohki, Masashi Mizuguchi
- Organizer
  第62回日本小児神経学会総会
- Data Source
  KAKENHI-PROJECT-18K07784
[Presentation] CDKL5欠損症の病態機序と治療法の解明を目指す私たちの研究2019
- Author(s)
  田中輝幸
- Organizer
  第12回全国てんかんリハビリテーション研究会
- Invited
- Data Source
  KAKENHI-PROJECT-18K07784
[Presentation] Dissecting the Cdkl5 mutant mice at the macroscopic, microscopic, and mesoscopic levels2019
- Author(s)
  Teruyuki Tanaka
- Organizer
  2019 CDKL5 Workshop in Asia
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07784
[Presentation] Pre-clinical study of the CDKL5 gene replacement therapy tested on the Cdkl5 knockout mouse2019
- Author(s)
  Teruyuki Tanaka, Elizabeth Zheng, Shin-ichi Muramatsu, Masashi Mizuguchi1
- Organizer
  第61回日本小児神経学会学術集会
- Data Source
  KAKENHI-PROJECT-18K07784
[Presentation] Can the gene replacement rescue the synaptic and behavioral phenotypes of mice deficient in Cyclin-dependent kinase-like 5 (CDKL5)?2019
- Author(s)
  Teruyuki Tanaka, Elizabeth Zheng, Shin-ichi Muramatsu, Masashi Mizuguchi
- Organizer
  第42回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-18K07784
[Presentation] CDKL5 controls synaptic localization of GluN2B-NMDA receptors and regulates seizure susceptibility2018
- Author(s)
  田中輝幸, 奥田耕助, 小林静香, 深谷昌弘, 渡邉紀, 村上拓冬, 萩原舞, 阪上洋行, 真鍋俊也, 水口雅
- Organizer
  第60回日本小児神経学会学術集会
- Data Source
  KAKENHI-PROJECT-18K07784
[Presentation] Comprehensive behavioral analysis of the Cdkl5 KO mice revealed significant enhancement in anxiety- and fear-related behaviors, alteration in depressive-like behaviors and social interaction, and impairment in both acquisition and long-term retention of spatial reference memory2018
- Author(s)
  Teruyuki Tanaka, Kosuke Okuda, Keizo Takao, Aya Watanabe, Masashi Mizuguchi, Tsuyoshi Miyakawa
- Organizer
  2018 CDKL5 Forum in London
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07784
[Presentation] CDKL5 controls postsynaptic localization of GluN2B-containing NMDA receptors in the hippocampus, and regulates seizure susceptibility, emotional behaviors, and memory2018
- Author(s)
  田中輝幸,　奥田耕助,　小林静香,　村上拓冬,　深谷昌弘,　高雄啓三,　渡邉紀,　萩原舞,　阪上洋行,　水口雅,　宮川剛,　真鍋俊也
- Organizer
  The 8th BRI International Symposium 2018, Niigata, Japan
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09614
[Presentation] CDKL5 controls postsynaptic localization of GluN2B-containing NMDA receptors in the hippocampus, and regulates seizure susceptibility, emotional behaviors, and memory2018
- Author(s)
  Teruyuki Tanaka, Kosuke Okuda, Shizuka Kobayashi, Takuto Murakami, Masahiro Fukaya, Keizo Takao, Aya Watanabe, Mai Hagiwara, Hiroyuki Sakagami, Masashi Mizuguchi, Tsuyoshi Miyakawa, Toshiya Manabe
- Organizer
  Cold Spring Harbor Asia - Latest Advances in Development & Function of Neuronal Circuits -
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07784
[Presentation] Comprehensive behavioral analysis of the Cdkl5 knockout mice revealed significant enhancement in anxiety- and fear-related behaviors, unique alteration in depressive-like behaviors and social interaction, and impairment in both acquisition and long-term retention of spatial reference memory2018
- Author(s)
  田中輝幸, 奥田耕助, 高雄啓三, 渡邉紀, 水口雅, 宮川剛
- Organizer
  第41回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-18K07784
[Presentation] Cdkl5 KOマウスのシナプス・行動学的解析：難治性てんかんを伴う神経発達障害CDKL5欠損症の病態機序と治療法の解明をめざして2018
- Author(s)
  田中輝幸
- Organizer
  立命館大学薬学部セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-18K07784
[Presentation] CDKL5 controls postsynaptic localization of GluN2B-containing NMDA receptors in the hippocampus and regulates seizure susceptibility2017
- Author(s)
  T. TANAKA, K. OKUDA, S. KOBAYASHI, M. FUKAYA, K. TAKAO, A. WATANABE, T. MURAKAMI, M. HAGIWARA, S. KOMANO-INOUE, H. MANABE, M. YAMAGUCHI, H. SAKAGAMI, T. MIYAKAWA, M. MIZUGUCHI, T. MANABE
- Organizer
  2017 CDKL5 Forum Meeting, Boston, USA
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09614
[Presentation] CDKL5 controls postsynaptic localization of GluN2B-containing NMDA receptors in the hippocampus and regulates seizure susceptibility2017
- Author(s)
  T. TANAKA, K. OKUDA, S. KOBAYASHI, M. FUKAYA, K. TAKAO, A. WATANABE, T. MURAKAMI, M. HAGIWARA, S. KOMANO-INOUE, H. MANABE, M. YAMAGUCHI, H. SAKAGAMI, T. MIYAKAWA, M. MIZUGUCHI, T. MANABE
- Organizer
  2017 Annual Meeting of the Society for Neuroscience, Washington, DC, USA
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09614
[Presentation] Comprehensive analyses of CDKL5, a causative gene product for neurodevelopment disorders West syndrome or atypical Rett syndrome2017
- Author(s)
  田中輝幸,　奥田耕助,　小林静香,　村上拓冬,　深谷昌弘,　高雄啓三,　渡邉紀,　萩原舞,　阪上洋行,　水口雅,　宮川剛,　真鍋俊也
- Organizer
  第40回日本神経科学大会、千葉市
- Data Source
  KAKENHI-PROJECT-15K09614
[Presentation] CDKL5 controls postsynaptic NMDA receptor localization and regulates memory, emotion and seizure susceptibility2016
- Author(s)
  村上拓冬、奥田耕助、小林静香、深谷昌弘、高雄啓三、近江信次、渡邉紀、萩原舞、阪上洋行、水口雅、宮川剛、真鍋俊也、田中輝幸
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜会議センター（神奈川県横浜市）
- Data Source
  KAKENHI-PROJECT-15K09614
[Presentation] CDKL5 controls postsynaptic NMDA receptor localization and regulates memory, emotion and seizure susceptibility2016
- Author(s)
  村上拓冬、奥田耕助、小林静香、深谷昌弘、高雄啓三、渡邉紀、萩原舞、阪上洋行、水口雅、宮川剛、真鍋俊也、田中輝幸
- Organizer
  第39回日本神経科学大会
- Place of Presentation
  パシフィコ横浜会議センター（神奈川県横浜市）
- Data Source
  KAKENHI-PROJECT-15K09614
[Presentation] CDKL5 controls glutamate receptor function and regulates memory, emotion and seizure susceptibility2015
- Author(s)
  田中輝幸、水口雅
- Organizer
  第57回日本小児神経学会総会
- Place of Presentation
  帝国ホテル　大阪　(大阪府大阪市)
- Year and Date
  2015-05-28
- Data Source
  KAKENHI-PROJECT-15K09614
[Presentation] West症候群・Rett症候群の原因遺伝子CDKL5は、NMDA受容体機能を制御し、記憶・学習、情動、易痙攣性を調節する2015
- Author(s)
  田中輝幸、奥田耕助、小林静香、村上拓冬、深谷昌弘、高雄啓三、渡邉紀、萩原舞、阪上洋行、水口雅、宮川剛、真鍋俊也
- Organizer
  第4５回日本神経精神薬理学会・第37回日本生物学的精神医学会
- Place of Presentation
  タワーホール船堀　(東京都江戸川区)
- Year and Date
  2015-09-25
- Data Source
  KAKENHI-PROJECT-15K09614
[Presentation] CDKL5 controls NMDA receptor function and regulates memory, emotion and seizure susceptibility2015
- Author(s)
  田中輝幸、奥田耕助、小林静香、深谷昌弘、高雄啓三、渡邉紀、村上拓冬、萩原舞、阪上洋行、水口雅、宮川剛、真鍋俊也
- Organizer
  第38回日本神経科学大会 Neuro 2015
- Place of Presentation
  神戸国際会議場　(兵庫県神戸市)
- Year and Date
  2015-07-28
- Data Source
  KAKENHI-PROJECT-15K09614
[Presentation] West 症候群/Rett 症候群の原因遺伝子 CDKL5 は、グルタミン酸受容体局在を制御し記憶/情動/易痙攣性を調節する2015
- Author(s)
  田中輝幸、奥田耕助、小林静香、深谷昌弘、高雄啓三、渡邉紀、村上拓冬、萩原舞、阪上洋行、水口雅、宮川剛、真鍋俊也
- Organizer
  第55回日本先天異常学会学術集会・第38回日本小児遺伝学会学術集会
- Place of Presentation
  パシフィコ横浜会議センター　(神奈川県横浜市)
- Year and Date
  2015-07-25
- Data Source
  KAKENHI-PROJECT-15K09614
[Presentation] Functional studies of the CDKL5, a causative gene of neurodevelopmental disorder, by interactome screening and loss-of-function analysis2013
- Author(s)
  Kosuke Okuda, Aya Watanabe, Shizuka Kobayashi, Toshiya Manabe, Keizo Takao, Tsuyoshi Miyakawa, Masahiro Fukaya, Hiroyuki Sakagami, Tomoki Nishioka, Mutsuki Amano, Kozo Kaibuchi, Masashi Mizuguchi, Teruyuki Tanaka
- Organizer
  第36回日本神経科学大会
- Place of Presentation
  京都市
- Data Source
  KAKENHI-PROJECT-23500381
[Presentation] 難治性てんかん・発達障害原因遺伝子CDKL5の生体内分子機能・病態機序解析2013
- Author(s)
  田中輝幸、奥田耕助、渡邉紀、小林静香、真鍋俊也、高雄啓三、宮川剛、深谷昌弘、阪上洋行、水口雅
- Organizer
  第54回日本神経病理学会総会学術研究会
- Place of Presentation
  東京都
- Data Source
  KAKENHI-PROJECT-23500381
[Presentation] West症候群・非典型Rett症候群の原因遺伝子CDKL5のノックアウトマウス作製・解析による病態機序の解明2013
- Author(s)
  田中輝幸、水口雅
- Organizer
  第55回日本小児神経学会総会
- Place of Presentation
  大分市
- Data Source
  KAKENHI-PROJECT-23500381
[Presentation] West症候群・非典型Rett症候群の原因遺伝子CDKL5の多元的アプローチによる分子機能・病態機序解析2012
- Author(s)
  田中輝幸、水口雅
- Organizer
  第54回日本小児神経学会総会
- Place of Presentation
  ロイトン札幌 (北海道札幌市)
- Data Source
  KAKENHI-PROJECT-23500381
[Presentation] 発達障害原因遺伝子CDKL5ノックアウトマウスの表現型解析2012
- Author(s)
  田中輝幸、奥田耕助、渡邉紀、竹本咲希、佐藤天平、上野寛枝、浅原弘嗣、水口雅
- Organizer
  第53回日本神経病理学会総会学術研究会
- Place of Presentation
  朱鷺メッセ (新潟県新潟市)
- Data Source
  KAKENHI-PROJECT-23500381
[Presentation] 遺伝子改変動物モデルによる神経発達障害研究と今後の展望」第85回日本産業衛生学会2012
- Author(s)
  田中輝幸
- Organizer
  第85回日本産業衛生学会
- Place of Presentation
  名古屋国際会議場 (愛知県名古屋市)
- Invited
- Data Source
  KAKENHI-PROJECT-23500381
[Presentation] 神経発達障害原因遺伝子CDKL5ノックアウトマウスの作製と表現型解析2012
- Author(s)
  田中輝幸、奥田耕助、渡邉紀、竹本咲希、佐藤天平、上野寛枝、浅原弘嗣、水口雅
- Organizer
  第52回日本先天異常学会学術集会
- Place of Presentation
  東京女子医科大学弥生記念講堂 (東京都新宿区)
- Data Source
  KAKENHI-PROJECT-23500381
[Presentation] Multidimensional analysis of the CDKL5, a causative gene for neurodevelopemental disorders2012
- Author(s)
  K. Okuda, A. Watanabe, S. Takemoto, M. Mizuguchi, T. Tanaka
- Organizer
  Annual Meeting of Society for Neuroscience 2012
- Place of Presentation
  Ernest N. Morial Convention Center (New Orleans, LA, USA)
- Data Source
  KAKENHI-PROJECT-23500381
[Presentation] Multidimensional analyses of the CDKL5, a causetive gene for neurodevelopmental disorders2012
- Author(s)
  Kosuke Okuda, Aya Watanabe, Saki Takemoto, Hiroe Ueno, Tempei Sato, Hiroshi Asahara, Masashi Mizuguchi, Teruyuki Tanaka
- Organizer
  第35回日本神経科学大会
- Place of Presentation
  名古屋国際会議場 (愛知県名古屋市)
- Data Source
  KAKENHI-PROJECT-23500381
[Presentation] Multidimensional approach to functional analysis of Cyclin-dependent kinase-like 5, the causative gene for atypical Rett syndrome2012
- Author(s)
  田中輝幸
- Organizer
  Rett Syndrome Symposium in Fukuoka
- Place of Presentation
  ホテルオークラ福岡 (福岡県福岡市)
- Invited
- Data Source
  KAKENHI-PROJECT-23500381
[Presentation] Identification and characterization of interacting proteins of Cdkl5, a gene product responsible for West syndrome or atypical Rett syndrome2011
- Author(s)
  Kousuke Okuda, Aya Watanabe, Saki Takemoto, Masashi Mizuguchi, Teruyuki Tanaka
- Organizer
  Society for Neuroscience Annual Meeting 2011
- Place of Presentation
  Walter E Washington Convention Center (ワシントンDC, アメリカ合衆国)
- Data Source
  KAKENHI-PROJECT-23500381
[Presentation] CDKL5の多元的アプローチによる機能解析 (シンポジウム：脳形成障害とオミックス)2011
- Author(s)
  田中輝幸、奥田耕助、渡邉紀、佐藤天平、上野寛枝、浅原弘嗣、水口雅
- Organizer
  第52回日本神経病理学会総会学術研究会(招待講演)
- Place of Presentation
  京都テルサ(京都府京都市)
- Data Source
  KAKENHI-PROJECT-23500381
[Presentation] Identification and Characterization of Interacting Proteins of CDKL5, a Gene Product Responsible for West Syndrome or Atypical Rett Syndrome2011
- Author(s)
  Kousuke Okuda, Aya Watanabe, Masashi Mizuguchi, Teruyuki Tanaka
- Organizer
  第34回日本神経科学大会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市)
- Data Source
  KAKENHI-PROJECT-23500381
[Presentation] 神経発達障害原因遺伝子CDKL5変異マウスの網羅的行動解析2011
- Author(s)
  田中輝幸
- Organizer
  2011年度包括型脳科学研究推進支援ネットワーク夏のワークショップ(招待講演)
- Place of Presentation
  神戸国際会議場(兵庫県神戸市)
- Data Source
  KAKENHI-PROJECT-23500381
[Presentation] 発達障害原因遺伝子の多元的アプローチによる機能解析2011
- Author(s)
  田中輝幸
- Organizer
  第23回産業神経・行動学研究会(招待講演)
- Place of Presentation
  名古屋大学医学部(愛知県名古屋市)
- Data Source
  KAKENHI-PROJECT-23500381
[Presentation] West症候群・非典型Rett症候群の原因遺伝子CDKL5の機能解析2010
- Author(s)
  田中輝幸
- Organizer
  第51回日本神経病理学会総会学術研究会
- Place of Presentation
  砂防会館(東京都千代田区)
- Year and Date
  2010-04-23
- Data Source
  KAKENHI-PROJECT-21659252
[Presentation] 難治性てんかんと発達障害の原因遺伝子CDKL5の相互作用同定による機能解明2010
- Author(s)
  奥田耕助、渡邉紀、水口雅、田中輝幸
- Organizer
  包括型脳科学研究推進支援ネットワーク夏のワークショップ
- Place of Presentation
  ホテルさつぽろ芸文館(北海道札幌市)
- Data Source
  KAKENHI-PROJECT-21659252
[Presentation] 難治性てんかんと発達遅滞の原因遺伝子CDKL5の相互作用の探索2010
- Author(s)
  奥田耕助、渡邉紀、水口雅、田中輝幸
- Organizer
  第33回日本神経科学大会
- Place of Presentation
  神戸コンベンションセンター(兵庫県神戸市)
- Year and Date
  2010-09-03
- Data Source
  KAKENHI-PROJECT-21659252
[Presentation] Doublecortinと大脳皮質形成 -ニューロン移動における力の伝達と方向性の制御機構解明へ向けて-2010
- Author(s)
  田中輝幸
- Organizer
  第41回慶應ニューロサイエンス研究会
- Place of Presentation
  慶應義大学医学部北里講堂(東京都) 招待講演
- Year and Date
  2010-11-06
- Data Source
  KAKENHI-PROJECT-21659252
[Presentation] 神経発達障害原因遺伝子CDKL5の分子機能解析2009
- Author(s)
  田中輝幸
- Organizer
  第4回メチレーションと小児神経学研究会「レット症候群とMECP2研究」
- Place of Presentation
  東京都文京区本郷本郷瀬川ビル
- Year and Date
  2009-08-23
- Data Source
  KAKENHI-PROJECT-21659252

1. MIZUGUCHI Masashi (20209753)

# of Collaborated Projects: 3 results

# of Collaborated Products: 24 results
2. ITO Hidenori (40311443)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. TSUKAMURA Hiroko (00212051)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. IWAHASHI Hitoshi (60356540)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. OZAKI Noriyuki (40244371)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. ICHIHARA Gaku (90252238)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. ICHIHARA Sahoko (20378326)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. SUGIURA Yasuo (50093042)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. YAMAMOTO Toshimichi (50260592)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. KAIBUCHI Kozo (00169377)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. MANABE Toshiya (70251212)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
12. FUKAYA Masahiro (10360900)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
13. TAKAO Keizo (80420397)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
14. Inazu Tetsuya (00242587)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
15. 天野睦紀 (90304170)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
16. 片山将一 (60779049)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. OKUDA Kosuke

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
18. MURAKAMI Takuto

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
19. 山口正洋

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Tanaka Teruyuki 田中 輝幸

TANAKA Teruyuki 田中 輝幸

田中 輝幸 タナカ テルユキ

Research Projects

Research Products

Co-Researchers

Molecular and neurocircuit mechanisms of excitatory/inhibitory imbalance and developmental disorders caused by CDKL5 kinase activity deficiencyPrincipal Investigator

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Creation of therapeutic agent for Rett syndrome (CDKL5 deficiency disorder) using Kampo medicine

Principal Investigator

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Pathomechanisms of developmental epileptic encephalopathy caused by CDKL5/CDKL3 mutations and development of the gene therapyPrincipal Investigator

Principal Investigator

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Review Section

Research Institution

Elucidating synaptic mechanisms and treatment of epileptic encephalopathy associated with CDKL5 mutationsPrincipal Investigator

Principal Investigator

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Research Institution

Multidimensional analyses of the CDKL5, a causative gene for neurodevelopment disorders, by proteomic and LOF approachesPrincipal Investigator

Principal Investigator

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Research Institution

難治性てんかん・非定型レット症候群の原因遺伝子欠損マウス作製・解析と分子標的解明Principal Investigator

Principal Investigator

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Analysis of molecular and cellular targets in neurotoxicity of alternatives to ozone-depleting substances and establishment of biomarkers for the central nervous toxicity

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[Journal Article] Effect of active vitamin D treatment on development of type 2 diabetes: DPVD randomised controlled trial in Japanese population2022

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[Journal Article] 発達障害の生物学的背景2019

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[Journal Article] Comprehensive behavioral analysis of the Cdkl5 knockout mice revealed significant enhancement in anxiety- and fear-related behaviors and impairment in both acquisition and long-term retention of spatial reference memory2018

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DOI

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[Journal Article] CDKL5 controls postsynaptic localization of GluN2B-containing NMDA receptors in the hippocampus and regulates seizure susceptibility.2017

Author(s)

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[Journal Article] Towards elucidating the regulatory roles of <i>CDKL5</i> in synaptic transmission2015

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[Journal Article] 小児の難治性てんかんとCDKL52013

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[Presentation] CDKL5機能喪失による発達性てんかん脳症 (CDKL5 欠損症) のマクロ・ミクロ・メゾスコピックスケール解析による病態機序の解明2023

Tanaka Teruyuki 田中輝幸

TANAKA Teruyuki 田中輝幸

田中輝幸タナカテルユキ