INAZU Tetsuya 稲津哲也

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Inazu Tetsuya 稲津哲也

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Researcher Number	00242587
Other IDs
Affiliation (Current)	2025: 立命館大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2025: 立命館大学, 薬学部, 教授 2019 – 2023: 立命館大学, 薬学部, 教授 1999: Fukui Medical University, Department of Biochemistry, Assistant Professor, 医学部, 助手 1993 – 1997: 福井医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Basic Section 52050:Embryonic medicine and pediatrics-related / General medical chemistry / Pathological medical chemistry Except Principal Investigator Endocrinology / General medical chemistry / Basic Section 59010:Rehabilitation science-related / Pathological medical chemistry
Keywords	Principal Investigator pleckstrin homology / CDKL5 / protein kinase C / チロシンキナーゼ / 機能異常症 / CDKL5欠損症 / 精神神経発達 / 希少疾患 / 病態解析 / ノックインマウス … More / 機能異常 / 漢方薬 / レット症候群 / 細胞内情報伝達 / 神経分化 / cdkl5ノックアウトマウス / Cdkl5ノックアウトマウス / 神経分化誘導作用 / 一味抜き成分 / 抑肝散 / genome DNA cloning / pleckstrin cDNA cloning / リン脂質 / ゲノムDNAクローニング / pleckstrin cDNAクローニング / 会合 / cDNA / 血球系 / syk … More Except Principal Investigator Syk / Lyn / 転写因子 / Shc / チロシンキナーゼ / inducible gene / transcription factor / ゴナドトロピン / トロンビン / p72syk / PLCγ / PI3キナーゼ / ピルビン酸キナーゼ遺伝子 / サルコペニア / human homologue / ovary / 遺伝子診断 / 腫瘍 / ホルモン誘導性 / ヒトホモローグ / 卵巣 / gene expression / gonadotropin / 卵胞発育 / 卵巣顆粒膜細胞 / 遺伝子発現 / 誘導性 / Homeobox gene / Hepatocytes / Transcription factor / Pyruvate kinase gene / Transcriptional regulation / ホメオボックス遺伝子 / 肝細胞 / 転写制御 / Thrombin / PI 3 kinase / Interleukin2 / PLCgamma / Tyrosine kinase / 活性化機構 / コンカナバリンA / トロンボキサンA_2 / インターロイキン2 / mast cell / FcgammaRIIIA / IgE receptor / B cell receptor / DT-40 cell / Protein-tyrosine kinase / 血小板 / B細胞受容体 / IgE受容体 / GAP / RBL-2H3細胞 / DT40細胞 / SH2 / 選択的スプライシング / HNF4 / NF1ファミリー / PI3-kinase / GTP結合蛋白質 Less

Muscle gain and strengthening effects of active vitamin D for prevention of sarcopenia.
- Principal Investigator
  
  河原哲也
- Project Period (FY)
  2025 – 2029
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59010:Rehabilitation science-related
- Research Institution
  University of Occupational and Environmental Health, Japan
Fundamental research to propose a novel disease of CDKL5 dysfunctionPrincipal Investigator
- Principal Investigator
  
  稲津哲也
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Ritsumeikan University
Creation of therapeutic agent for Rett syndrome (CDKL5 deficiency disorder) using Kampo medicinePrincipal Investigator
- Principal Investigator
  
  Inazu Tetsuya
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Ritsumeikan University
Research on the role of a new hormone-inducible transcription factor GIOT for the ovarian function.
- Principal Investigator
  
  MIYAMOTO Kaoru
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Endocrinology
- Research Institution
  Fukui Medical University
  Gunma University
Applied research for the development of gene diagnosis of ovarian dysfunction using a novel ovarian transcription factor GIOT.
- Principal Investigator
  
  MIYAMOTO Kaoru
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Endocrinology
- Research Institution
  Fukui Medical University
  Gunma University
Regulation of transcription and splicing of pyruvate kinase isozyme genes
- Principal Investigator
  
  NOGUCHI Tamio
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Nagoya University
  福井医科大学
ピルビン酸キナーゼアイソザイム遺伝子の転写とスプライシングを制御する因子
- Principal Investigator
  
  NOGUCHI Tamio
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  福井医科大学
Functional and physiological analysis of plechstrin homology domain structurePrincipal Investigator
- Principal Investigator
  
  INAZU Tetsuya
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Fukui Medical School
蛋白質チロシンキナーゼp72^<Syk>を介する細胞内情報伝達とG蛋白質
- Principal Investigator
  
  YAMAMURA Hirohei
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  福井医科大学
プレクストリン(血小板47KD蛋白)構造を有する遺伝子の同定とその機能Principal Investigator
- Principal Investigator
  
  稲津哲也
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  General medical chemistry
- Research Institution
  福井医科大学
非受容体型蛋白質チロシンキナーゼp72^<syk>のヒト遺伝子並びに関連遺伝子の同定Principal Investigator
- Principal Investigator
  
  稲津哲也
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  General medical chemistry
- Research Institution
  福井医科大学
Physiological role of protein-tyrosine kinase p72^<syk>
- Principal Investigator
  
  YAMAMURA Hirohei
- Project Period (FY)
  1993 – 1995
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Kobe University
  福井医科大学
Physiological function of non-receptor type protein-tyrosine kinase p72^<syk>
- Principal Investigator
  
  YAMAMURA Hirohei
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  KOBE UNIBERSITY
  福井医科大学

All 2024 2023 2022 2021 2020 2019

All Journal Article Presentation

[Journal Article] Role of plant homeodomain finger protein 8 in P19 embryonic carcinoma cells revealed by genome editing and specific inhibitor2024
- Author(s)
  Doi Shusuke、Suzuki Takayoshi、Soeda Shuhei、Miyata Naoki、Inazu Tetsuya
- Journal Title
  
  Biochemistry and Biophysics Reports
  
  Volume: 38 Pages: 101670-101670
- DOI
  10.1016/j.bbrep.2024.101670
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K07235, KAKENHI-PROJECT-21H04795
[Journal Article] Total colectomy for poorly controlled hypokalemia due to Gitelman syndrome2023
- Author(s)
  Tetsuya Kawahara, Tetsuya Inazu, Shingo Ishida
- Journal Title
  
  BMJ Case Reports
  
  Volume: 16(2):e252916. Issue: 2 Pages: e252916-e252916
- DOI
  10.1136/bcr-2022-252916
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08264
[Journal Article] Comprehensive in silico functional prediction analysis of CDKL5 by single amino acid substitution in the catalytic domain2022
- Author(s)
  Yuri Yoshimura , Atsushi Morii, Yuuki Fujino, Marina Nagase, Arisa Kitano, Shiho Ueno, Kyoka Takeuchi, Riko Yamashita, Tetsuya Inazu
- Journal Title
  
  Int. J. Mol. Sci.
  
  Volume: 23(20) Issue: 20 Pages: 12281-12281
- DOI
  10.3390/ijms232012281
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08264
[Journal Article] Effect of active vitamin D treatment on development of type 2 diabetes: DPVD randomised controlled trial in Japanese population2022
- Author(s)
  Tetsuya Kawahara, Gen Suzuki, Shoichi Mizuno, Tetsuya Inazu, Fumiyoshi Kasagi, Chie Kawahara, Yosuke Okada, Yoshiya Tanaka
- Journal Title
  
  BMJ
  
  Volume: 377 Pages: e066222-e066222
- DOI
  10.1136/bmj-2021-066222
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08264
[Journal Article] HDAC8 is implicated in embryoid body formation via canonical Hedgehog signaling and regulates neuronal differentiation2022
- Author(s)
  Atsushi Morii, Tetsuya Inazu
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 629 Pages: 78-85
- DOI
  10.1016/j.bbrc.2022.08.068
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08264
[Journal Article] Zinc finger protein 483 (ZNF483) regulates neuronal differentiation and methyl-CpG-binding protein 2 (MeCP2) intracellular localization2021
- Author(s)
  Yasui Gen、Katayama Syouichi、Kubota Yukihiko、Takatsuka Hisashi、Ito Masahiro、Inazu Tetsuya
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 568 Pages: 68-75
- DOI
  10.1016/j.bbrc.2021.06.066
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08264, KAKENHI-PROJECT-20K15751
[Journal Article] Establishment of a Simple Method for Inducing Neuronal Differentiation of P19 EC Cells without Embryoid Body Formation and Analysis of the Role of Histone Deacetylase 8 Activity in This Differentiation2020
- Author(s)
  Atsushi Morii, Syouichi Katayama, Tetsuya Inazu
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 43 Issue: 7 Pages: 1096-1103
- DOI
  10.1248/bpb.b20-00091
- NAID
  130007867918
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2020-07-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08264
[Journal Article] Cyclin-dependent kinase-like 5 (CDKL5): Possible cellular signaling targets and involvement in CDKL5 deficiency disorder2020
- Author(s)
  Syouichi Katayama, Noriyuki Sueyoshi, Tetsuya Inazu, Isamu Kameshita
- Journal Title
  
  Neural Plasticity
  
  Volume: volume 2020 Pages: 6970190-6970190
- DOI
  10.1155/2020/6970190
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08264, KAKENHI-PROJECT-20K15751
[Journal Article] Yokukansan, a Kampo medicine, enhances the level of neuronal lineage markers in differentiated P19 embryonic carcinoma cells2019
- Author(s)
  Fukui Makoto、Katayama Syouichi、Ikeya Yukinobu、Inazu Tetsuya
- Journal Title
  
  Heliyon
  
  Volume: 5 Issue: 10 Pages: e02662-e02662
- DOI
  10.1016/j.heliyon.2019.e02662
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08264
[Journal Article] In Silico Study of Rett Syndrome Treatment-Related Genes, MECP2, CDKL5, and FOXG1, by Evolutionary Classification and Disordered Region Assessment2019
- Author(s)
  Fahmi Muhamad、Yasui Gen、Seki Kaito、Katayama Syouichi、Kaneko-Kawano Takako、Inazu Tetsuya、Kubota Yukihiko、Ito Masahiro
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 20 Issue: 22 Pages: 5593-5593
- DOI
  10.3390/ijms20225593
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08264
[Presentation] Efficacy of active vitamin D treatment to prevent sarcopenia in adults with prediabetes: randomized controlled trial2024
- Author(s)
  Tetsuya Kawahara, Gen Suzuki, Shoichi Mizuno, Naoki Tominaga, Yoshiya Tanaka, Tetsuya Inazu
- Organizer
  The 21st International Congress of Endocrinology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K07235
[Presentation] Active Vitamin D Treatment and Prevention of Sarcopenia in Adults with Prediabetes2023
- Author(s)
  Tetsuya Kawahara, Gen Suzuki, Shoichi Mizuno, Naoki Tominaga, Hideki Yamada, Mikio Toda, Nagahiro Toyama, Chie Kawahara, Yosuke Okada, Yoshiya Tanaka, Tetsuya Inazu
- Organizer
  9th Asian Conference for Frailty and Sarcopenia
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K07235
[Presentation] P19細胞における神経分化過程でのhistone deacetylase 8の機能解析2023
- Author(s)
  森井篤、稲津哲也
- Organizer
  日本薬学143年会
- Data Source
  KAKENHI-PROJECT-19K08264
[Presentation] CDKL5 ノックインマウスの行動解析2022
- Author(s)
  武内杏夏、鎌田雅之、稲津哲也
- Organizer
  国際稀少疾患シンポジウム　2022 at Ritsumeikan
- Data Source
  KAKENHI-PROJECT-19K08264
[Presentation] レット症候群原因遺伝子CDKL5の触媒部位内１アミノ酸置換による網羅的in silico 機能予測解析と臨床報告例との相関2022
- Author(s)
  吉村優里、藤野優希、森井篤、武内杏夏、北野有砂、山下莉子、上野支帆、Muhamad Fahmi、伊藤將弘、稲津哲也
- Organizer
  日本薬学会　第142年会（名古屋）
- Data Source
  KAKENHI-PROJECT-19K08264
[Presentation] レット症候群原因遺伝子 CDKL5 の触媒部位内1アミノ酸置換による網羅的 in silico 機能予測解析2022
- Author(s)
  吉村優里、森井篤、藤野優希、武内杏夏、北野有砂、山下莉子、上野支帆、稲津哲也
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K08264
[Presentation] レット症候群原因遺伝子 CDKL5 の触媒部位内1アミノ酸置換による網羅的 in silico 機能予測解析2022
- Author(s)
  吉村優里、森井篤、藤野優希、武内杏夏、北野有砂、山下莉子、上野支帆、稲津哲也
- Organizer
  国際稀少疾患シンポジウム 2022 at Ritsumeikan
- Data Source
  KAKENHI-PROJECT-19K08264
[Presentation] HDAC8の欠損は神経分化不全を導く2020
- Author(s)
  森井篤、片山将一、稲津哲也
- Organizer
  第70回日本薬学会関西支部総会
- Data Source
  KAKENHI-PROJECT-19K08264
[Presentation] Phf8ノックアウトP19胚性腫瘍細胞株の樹立とその解析2020
- Author(s)
  土井秀介、森井篤、片山将一、稲津哲也
- Organizer
  第43回　日本分子生物学会年会　2020/12/3
- Data Source
  KAKENHI-PROJECT-19K08264
[Presentation] Yokukansan, a Japanese traditional medicine, enhances the level of neuronal lineage markers in differentiated wild and cdkl5 knockout P19 embryonic carcinoma cells2020
- Author(s)
  Tetsuya Inazu, Makoto Fukui, Sakino Iwata, Yukinobu Ikeya, Syouichi Katayama
- Organizer
  CDKL5 Forum 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08264
[Presentation] P19EC細胞における「一味抜き抑肝散」の神経分化への効果検討2020
- Author(s)
  岩田彩生乃、片山将一、池谷幸信、稲津哲也
- Organizer
  第70回日本薬学会関西支部総会
- Data Source
  KAKENHI-PROJECT-19K08264
[Presentation] P19細胞における神経分化過程でのHDAC8の機能解析2020
- Author(s)
  森井篤、片山将一、稲津哲也
- Organizer
  日本薬学会　第140年会（京都）
- Data Source
  KAKENHI-PROJECT-19K08264
[Presentation] ドッキングシュミレーションによるCyclin-dependent kinase-like 5の基質タンパク質同定2020
- Author(s)
  高原　亜邪、片山将一、河野貴子、稲津哲也、菊地武司
- Organizer
  第58回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-19K08264
[Presentation] Phf8ノックアウトP19胚性腫瘍細胞株を用いたPHF8の機能解析2020
- Author(s)
  土井秀介、森井篤、片山将一、稲津哲也
- Organizer
  第70回日本薬学会関西支部総会
- Data Source
  KAKENHI-PROJECT-19K08264
[Presentation] Expression analysis of Rett syndrome-related genetic factors, e.g. CDKL5, in HDAC8 knockout P19 cells2019
- Author(s)
  Atsushi Morii, Mako Saito, Syouichi Katayama, Tetsuya Inazu
- Organizer
  CDKL5 Workshop in Asia
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08264
[Presentation] Hdac8 KO P19細胞におけるRett症候群関連因子の発現変動とその解析2019
- Author(s)
  森井篤、片山将一、斎藤磨子、土井秀介、稲津哲也
- Organizer
  第69回日本薬学会関西支部総会
- Data Source
  KAKENHI-PROJECT-19K08264
[Presentation] PDGFとCDKL5はNeuro2a細胞の神経突起伸長を制御する2019
- Author(s)
  南光貴裕、坂口逸紀、土井秀介、森井篤、片山将一、稲津哲也
- Organizer
  第69回日本薬学会関西支部総会
- Data Source
  KAKENHI-PROJECT-19K08264
[Presentation] A novel CDKL5 mutation in an atypical Rett syndrome patient and development a convenient method for detecting CDKL5 activity2019
- Author(s)
  Syouichi Katayama, Tetsuya Inazu
- Organizer
  CDKL5 Workshop in Asia
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08264
[Presentation] Yokukansan, a Kampo medicine, enhances the level of neuronal lineage markers in differentiated P19 embryonic carcinoma cells2019
- Author(s)
  Syouichi Katayama, Makoto Fukui, Sayaka Suzuki , Yukinobu Ikeya , Tetsuya Inazu
- Organizer
  CDKL5 Workshop in Asia
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08264

1. MARUYAMA Shingo (90262633)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. YAMAMURA Hirohei (90030882)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. YANAGI Shigeru (60252003)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. NOGUCHI Tamio (70135721)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. YAMADA Kazuya (20263238)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. TANIGUCHI Takanobu (60217130)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. MIYAMOTO Kaoru (30125877)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. 峯岸敬 (00209842)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. 保坂公平 (70108992)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. YAMAMOTO Tadashi (40134621)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. SADA Kiyonao (10273765)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. MINAMI Yasuhiro (70229772)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 竹内郁登 (70262623)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 田中輝幸 (10246647)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
15. 片山将一 (60779049)

# of Collaborated Projects: 1 results

# of Collaborated Products: 16 results
16. 池田宏輝 (70819911)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 河原哲也 (30389431)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. KUROSAKI Tomohiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. KINET Jean-pierre

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. TOMOHIRO Kur

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

INAZU Tetsuya 稲津 哲也

Inazu Tetsuya 稲津 哲也

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Fundamental research to propose a novel disease of CDKL5 dysfunctionPrincipal Investigator

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Creation of therapeutic agent for Rett syndrome (CDKL5 deficiency disorder) using Kampo medicinePrincipal Investigator

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Functional and physiological analysis of plechstrin homology domain structurePrincipal Investigator

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プレクストリン(血小板47KD蛋白)構造を有する遺伝子の同定とその機能Principal Investigator

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非受容体型蛋白質チロシンキナーゼp72^<syk>のヒト遺伝子並びに関連遺伝子の同定Principal Investigator

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[Journal Article] Role of plant homeodomain finger protein 8 in P19 embryonic carcinoma cells revealed by genome editing and specific inhibitor2024

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DOI

Data Source

[Journal Article] Total colectomy for poorly controlled hypokalemia due to Gitelman syndrome2023

Author(s)

INAZU Tetsuya 稲津哲也

Inazu Tetsuya 稲津哲也