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NOGUCHI Tamio
野口 民夫
Connect your ORCID iD
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Alternative Names
野口 民男
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Researcher Number
70135721
External Links
Affiliation (based on the past Project Information)
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2006 – 2007: 大阪大谷大学, 薬学部, 教授
1999 – 2004: 名古屋大学, 大学院・生命農学研究科, 教授
1998: Nagoya University Professor., 大学院・農学研究科, 教授
1998: Nagoya university, Agriculture, Professor, 農学部, 教授
1997: 福井医科大学医学部, 生化学教室, 教授
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1995 – 1997: 福井医科大学, 医学部, 教授
1992 – 1994: Osaka University Nutr. & Physiol. Chem Assoc. Pro, 医学部, 助教授
1987 – 1991: 大阪大学, 医学部, 講師
1989: 大阪大学, 医学部, 構師
1986 – 1987: Osaka University Medical School, 医学部, 助手
1986: 阪大, 医学部, 助手
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Review Section/Research Field
Principal Investigator
General medical chemistry
/
Food science
/
食品科学・栄養科学
/
Biological Sciences
/
Pathological medical chemistry
Except Principal Investigator
内分泌・代謝学
/
Pathological medical chemistry
/
代謝生物化学
/
General medical chemistry
Keywords
Principal Investigator
転写因子 / Transcription factor / ピルビン酸キナーゼ遺伝子 / ChREBP / インスリン / ピルビン酸キナーゼ / Sp1 / 転写制御 / Transcriptional regulation / L型ピルビン酸キナーゼ
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More
/ SREBP1 / 組織特異的発現 / Sp3 / HNF4 / プロモーター / Tissue-specific expression / NF-Y / 肝細胞 / 転写調節 / Insulin / シス作用領域 / Hex / Pyruvate kinase gene / ピルビン酸キナーゼアイソザイム / 選択的スプライシング / ホメオボックス遺伝子 / NF1ファミリー / グルコース / L型ピルヒン酸キナーゼ遺伝子 / シス作用制御領域 / トランスジェニックマウス / RNAプロセシング / PGC1α / グルコース制御 / HNF1α / PGC1 / 肝特異的転写因子 / Oxidative stress / Pyruvate kinase / L型ピルビン酸キナ-ゼ / PGC-1α / Spl / Carbohydrate responsive gene / Transgeninic mice / cis-Acting element / グルコキナーゼ遺伝子 / Insulin response element / NF1 / レポーターアッセイ / 炭水化物応答性遺伝子 / タンパク質相互作用 / NFY / Enhancer / アロステリック制御 / L-type pyruvate kinase gene / Adipocytes / ピルビン酸キナ-ゼ遺伝子 / PGC-Iα / Pyruvate kinase isozymes / Glucose / Alternative splicing / 酸化ストレス / Liver / Hepatocytes / Protein interaction / 肝臓 / 炭水化物応答性 / Mlx / グルコキナ-ゼ / CATアッセイ / Glucokinase gene / Pyruvate kinase genes / エンハンサ- / SREBP / 分化 / 非受容体型転写因子 / エンハンサー / インスリンシグナル伝達 / グルコキナーゼ / インスリン反応性領域 / Homeobox gene / 相互作用 / 脂肪細胞 / L型ピルビン酸キナーゼ遺伝子 / 脂肪酸合成酵素 / 発生 / ChREBP結合タンパク質 / トランスジュニックマウス / L-type pyruvate kinase
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More
Except Principal Investigator
遺伝子クローニング / 遺伝子発現制御機構 / 前がん病変 / 酵素変異 / 肝発がん / ピルビン酸キナーゼアイソザイム / 組織特異的発現 / がん遺伝子 / L型ピルビン酸キナ-ゼ / 解糖系 / Glycolysis / protein kinase C / Insulin / シス作用領域 / インスリン / エンハンサ- / pleckstrin homology / Gタンパク質 / 変性LDL / LFーB1 / Apolipoprotein B / プロティンホスファタ-ゼ / Hemolytic anemia / マ-カ-酵素 / Regulation of gene expression / フルクトース / グルタチオン / Sitosterolemia / RNAプロセシング / Denatured LDL / Gene analysis / Low density lipoproteins(LDL) / 肝発癌 / LDL path way / 肝特異的転写因子 / Tissue-specific expression / アポリポ蛋白B / S-トランスフェラーゼ / 先天代謝異常 / cDNAクロ-ニング / 転写調節 / 癌遺伝子 / Genomic structure / 低ベ-タリポ蛋白血症 / アポB isoform / スプライシング / 低βリポ蛋白血症 / Transcriptional regulation / ホスホフルクトキナーゼ欠損症(グリコーゲン病VII型) / アポB100 / LDL / Genetic disease / 律速酵素 / L型ピルビン酸キナーゼ / L遺伝子 / 転写因子 / ゲノムDNAクローニング / Phosphofructokinase / ピルビン酸キナーゼ遺伝子 / 肝癌 / Enhancer / 細胞特量的発現 / 動脈硬化症 / 制御領域 / 溶血性貧血 / 遺伝子治療 / Hepatocyte-specific transcription factor / Type VII glycogenosis / プロテアソ-ム / CAT assay / Erythroenzymopathies / 遺伝子解析 / 遺伝子構造 / 転写調節因子 / cDNAクローニング / M_2型ピルビン酸キナ-ゼ / ピルビン酸キナ-ゼ遺伝子 / グリコ-ゲン病VII型 / ホスホフルクトキナ-ゼ / 低比重リポ蛋白(LDL) / Pyruvate kinase isozymes / genome DNA cloning / 異常遺伝子 / 一次構造 / Key enzyme / ピルビン酸キナーゼL遺伝子 / 培養細胞 / pleckstrin cDNA cloning / Transgenic mice / Atherosclerosis / ピルビン酸キナ-ゼアイソザイム / 糖尿病 / マクロファージ / 代謝異常 / シス作用制御領域 / アポB48 / 疾患モデルマウス / Cis-acting element / 遺伝子変異 / アポBイソ蛋白 / 動脈硬化 / 細胞特異的発現 / Hypobetalipoproteinemia / グルタチオン Sートランスフェラーゼ / pleckstrin cDNAクローニング / 遺伝病 / Splicing / CATアッセイ / Gene therapy / 遺伝子発現の調節 / M遺伝子 / Fructose-L-type pyruvate kinase / グルタチオンSートランスフェラーゼ / 遺伝子クロ-ニング / 変性リポ蛋白 / シトステロ-ル血症 / 低Bリポ蛋白血症 / LDL pathway / リン脂質 / cDNA cloning / Metabolic disorder / Diabetes mellitus / オルタナティブスプライシング / グルタチオンSートランスフェラ-ゼ / Genomic cloning / タンパク質工学
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Research Projects
(
27
results)
Co-Researchers
(
27
People)
Project Start Year (Newest)
Project Start Year (Oldest)
Elucidation of glucose responsive transcription factor complexes of L-type pyruvate kinase gene
Principal Investigator
Principal Investigator
NOGUCHI Tamio
Project Period (FY)
2006 – 2007
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Food science
Research Institution
Otani Womens University
非受容体型転写因子の活性を制御する食品成分の検索
Principal Investigator
Principal Investigator
野口 民夫
Project Period (FY)
2003 – 2004
Research Category
Grant-in-Aid for Exploratory Research
Research Field
Food science
Research Institution
Nagoya University
Molecular mechanism of transcriptional regulation of pyruvate kinase gene by glucose and insulin
Principal Investigator
Principal Investigator
NOGUCHI Tamio
Project Period (FY)
2002 – 2004
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
食品科学・栄養科学
Research Institution
Nagoya University
肝細胞の発生と分化を司る遺伝子システムにおけるHexの役割の解明
Principal Investigator
Principal Investigator
野口 民夫
Project Period (FY)
2000
Research Category
Grant-in-Aid for Scientific Research on Priority Areas (C)
Review Section
Biological Sciences
Research Institution
Nagoya University
Regulation of enzyme activity and gene expression of pyruvate kinase by dietary factors
Principal Investigator
Principal Investigator
NOGUCHI Tamio
Project Period (FY)
1999 – 2001
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
食品科学・栄養科学
Research Institution
Nagoya University
Regulation of transcription and splicing of pyruvate kinase isozyme genes
Principal Investigator
Principal Investigator
NOGUCHI Tamio
Project Period (FY)
1997 – 1998
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
General medical chemistry
Research Institution
Nagoya University
福井医科大学
Regulation of human pyruvate kinase gene in red cells
Principal Investigator
KANNO Hitoshi
Project Period (FY)
1997 – 1998
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Pathological medical chemistry
Research Institution
Okinaka Memorial Institute for Medical Research
ピルビン酸キナーゼアイソザイム遺伝子の転写とスプライシングを制御する因子
Principal Investigator
Principal Investigator
野口 民夫
Project Period (FY)
1996
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
General medical chemistry
Research Institution
福井医科大学
Functional and physiological analysis of plechstrin homology domain structure
Principal Investigator
INAZU Tetsuya
Project Period (FY)
1995 – 1996
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Pathological medical chemistry
Research Institution
Fukui Medical School
L型ピルビン酸キナーゼ遺伝子のエンハンサーユニットに結合する転写因子の構造と機能
Principal Investigator
Principal Investigator
野口 民夫
Project Period (FY)
1994
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
General medical chemistry
Research Institution
Osaka University
インスリンによる転写調節の分子機構とその異常
Principal Investigator
Principal Investigator
野口 民夫
Project Period (FY)
1993
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Pathological medical chemistry
Research Institution
Osaka University
肝癌におけるピルビン酸キナ-ゼアイソザイムの遺伝子発現を制御する因子
Principal Investigator
田中 武彦
Project Period (FY)
1991
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Osaka University
Molecular mechanism of transcriptional regulation by insulin
Principal Investigator
Principal Investigator
NOGUCHI Tamio
Project Period (FY)
1991 – 1992
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
General medical chemistry
Research Institution
Osaka University
肝発癌過程のマ-カ-酵素の特異的発現機構と機能の解明
Principal Investigator
佐藤 清美
Project Period (FY)
1990
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Hirosaki University
肝癌におけるピルビン酸キナ-ゼアイソザイムの遺伝子発現を制御する因子
Principal Investigator
TANAKA Takehiko
Project Period (FY)
1990
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Osaka University
肝化学発癌過程の前癌細胞における遺伝子および遺伝子発現の異常の解析
Principal Investigator
佐藤 清美
Project Period (FY)
1989
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Hirosaki University
Cis-Acting and Trans-Acting Elements that Regulate Tissue-Specific Gene Expression
Principal Investigator
Principal Investigator
NOGUCHI Tamio
Project Period (FY)
1989 – 1990
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
General medical chemistry
Research Institution
Osaka University
肝化学発癌過程の前癌細胞における遺伝子および遺伝子発現の異常の解析
Principal Investigator
佐藤 清美
Project Period (FY)
1988
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Hirosaki University
Molecular biological investigation into the enzyme abnormality in muscle phosphofructokinase deficiency
Principal Investigator
TARUI Seiichiro
Project Period (FY)
1988 – 1989
Research Category
Grant-in-Aid for General Scientific Research (A)
Research Field
内分泌・代謝学
Research Institution
Osaka University Medical School
Regulatory mechanisms of gene expression of pyruvate kinase isozymes
Principal Investigator
TANAKA Takehiko
Project Period (FY)
1988 – 1989
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
General medical chemistry
Research Institution
Osaka University
肝化学発癌過程の前癌細胞における遺伝子および遺伝子発現の異常の解析
Principal Investigator
佐藤 清美
Project Period (FY)
1987
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Hokkaido University
癌遺伝子の発現とアイソザイムの偏倚
Principal Investigator
田中 武彦
Project Period (FY)
1987 – 1988
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Osaka University
Factors responsible for tissue-specific gene expression
Principal Investigator
Principal Investigator
NOGUCHI Tamio
Project Period (FY)
1987 – 1988
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
General medical chemistry
Research Institution
Osaka University
癌遺伝子の発現とアイソザイムの偏倚
Principal Investigator
田中 武彦
Project Period (FY)
1986
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Osaka University
プロセシングの違いによるピルビン酸キナーゼアイソザイムのmRNAの生成とその調節
Principal Investigator
Principal Investigator
野口 民夫
Project Period (FY)
1986
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
General medical chemistry
Research Institution
Osaka University
Analysis of abnormal LDL metabolism and gene analysis of apolipoprotein B
Principal Investigator
SHIGETA Yukio
Project Period (FY)
1986 – 1989
Research Category
Grant-in-Aid for General Scientific Research (A)
Research Field
内分泌・代謝学
Research Institution
Shiga University of Medical Science
Regulatory mechanisms of gene expression of hepatic enzyme by insulin and fructose
Principal Investigator
TANAKA Takehiko
Project Period (FY)
1985 – 1986
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
代謝生物化学
Research Institution
Osaka University
# of Projects (Dsc)
# of Projects (Asc)
1.
TANAKA Takehiko
(60028272)
# of Collaborated Projects:
6 results
# of Collaborated Products:
0 results
2.
佐藤 清美
(50006079)
# of Collaborated Projects:
4 results
# of Collaborated Products:
0 results
3.
村松 正實
(10035454)
# of Collaborated Projects:
4 results
# of Collaborated Products:
0 results
4.
津田 洋幸
(10163809)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
5.
渡部 烈
(00057316)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
6.
INAZU Tetsuya
(00242587)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
7.
YAMADA Kazuya
(20263238)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
8.
菊池 九二三
(20006117)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
9.
林 健志
(00019671)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
10.
宮城 妙子
(50006110)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
11.
谷口 直之
(90002188)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
12.
今井 圓裕
(00223305)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
13.
立木 蔚
(90006065)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
14.
MARUYAMA Shingo
(90262633)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
15.
KANNO Hitoshi
(70221207)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
16.
KOIZUMI Tsutomu
(40126579)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
17.
MIWA Shiro
(40034954)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
18.
岡田 統子
(70303584)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
19.
SHIGETA Yukio
(60028321)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
20.
KOSUGI Keisuke
(00153544)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
21.
HIDAKA Hideki
(80156603)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
22.
KASHIWAGI Atsunori
(20127210)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
23.
HARANO Yutaka
(10028615)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
24.
TARUI Seiichiro
(00028341)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
25.
SHIMIZU Takao
(40206199)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
26.
KUWAJIMA Masamichi
(00205262)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
27.
KONO Norio
(30093412)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
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