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NOGUCHI Tamio
野口 民夫
Connect your ORCID iD
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Alternative Names
野口 民男
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Researcher Number
70135721
External Links
Affiliation (based on the past Project Information)
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2006 – 2007: 大阪大谷大学, 薬学部, 教授
1999 – 2004: 名古屋大学, 大学院・生命農学研究科, 教授
1998: Nagoya University Professor., 大学院・農学研究科, 教授
1998: Nagoya university, Agriculture, Professor, 農学部, 教授
1997: 福井医科大学医学部, 生化学教室, 教授
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1995 – 1997: 福井医科大学, 医学部, 教授
1992 – 1994: Osaka University Nutr. & Physiol. Chem Assoc. Pro, 医学部, 助教授
1987 – 1991: 大阪大学, 医学部, 講師
1989: 大阪大学, 医学部, 構師
1986 – 1987: Osaka University Medical School, 医学部, 助手
1986: 阪大, 医学部, 助手
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Review Section/Research Field
Principal Investigator
General medical chemistry
/
Food science
/
食品科学・栄養科学
/
Pathological medical chemistry
/
Biological Sciences
Except Principal Investigator
Pathological medical chemistry
/
内分泌・代謝学
/
代謝生物化学
/
General medical chemistry
Keywords
Principal Investigator
転写因子 / Transcription factor / ピルビン酸キナーゼ / インスリン / ピルビン酸キナーゼ遺伝子 / ChREBP / L型ピルビン酸キナーゼ / Sp1 / SREBP1 / 転写制御
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More
/ Transcriptional regulation / NF1ファミリー / HNF4 / 選択的スプライシング / Hex / ホメオボックス遺伝子 / 肝細胞 / Sp3 / プロモーター / ピルビン酸キナーゼアイソザイム / 組織特異的発現 / シス作用領域 / Tissue-specific expression / 転写調節 / Pyruvate kinase gene / グルコース / Insulin / NF-Y / グルコキナーゼ / 発生 / 分化 / 脂肪酸合成酵素 / 非受容体型転写因子 / Mlx / SREBP / レポーターアッセイ / RNAプロセシング / ピルビン酸キナ-ゼ遺伝子 / エンハンサ- / CATアッセイ / 肝特異的転写因子 / Pyruvate kinase genes / Enhancer / Alternative splicing / cis-Acting element / L型ピルビン酸キナーゼ遺伝子 / グルコキナーゼ遺伝子 / インスリン反応性領域 / トランスジュニックマウス / L型ピルヒン酸キナーゼ遺伝子 / トランスジェニックマウス / L型ピルビン酸キナ-ゼ / グルコキナ-ゼ / L-type pyruvate kinase gene / Glucokinase gene / Insulin response element / Transgeninic mice / Hepatocytes / Homeobox gene / 酸化ストレス / インスリンシグナル伝達 / グルコース制御 / NFY / アロステリック制御 / Oxidative stress / タンパク質相互作用 / 肝臓 / 脂肪細胞 / HNF1α / NF1 / 炭水化物応答性 / 相互作用 / エンハンサー / Pyruvate kinase / Glucose / Protein interaction / Liver / Adipocytes / 炭水化物応答性遺伝子 / PGC-Iα / PGC-1α / ChREBP結合タンパク質 / PGC1 / Carbohydrate responsive gene / L-type pyruvate kinase / PGC1α / Spl / シス作用制御領域 / Pyruvate kinase isozymes
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More
Except Principal Investigator
遺伝子クローニング / 肝発がん / 前がん病変 / 酵素変異 / 遺伝子発現制御機構 / ピルビン酸キナーゼアイソザイム / エンハンサ- / シス作用領域 / 組織特異的発現 / L型ピルビン酸キナ-ゼ / がん遺伝子 / pleckstrin homology / protein kinase C / 解糖系 / Glycolysis / インスリン / Insulin / グルタチオンSートランスフェラーゼ / タンパク質工学 / 肝発癌 / マ-カ-酵素 / グルタチオンSートランスフェラ-ゼ / 転写調節因子 / 癌遺伝子 / Gタンパク質 / プロティンホスファタ-ゼ / プロテアソ-ム / ピルビン酸キナ-ゼ遺伝子 / 肝癌 / M_2型ピルビン酸キナ-ゼ / 転写因子 / LFーB1 / オルタナティブスプライシング / ピルビン酸キナーゼ遺伝子 / RNAプロセシング / グルタチオン Sートランスフェラーゼ / M遺伝子 / L遺伝子 / 制御領域 / グルタチオン / S-トランスフェラーゼ / pleckstrin cDNAクローニング / ゲノムDNAクローニング / リン脂質 / pleckstrin cDNA cloning / genome DNA cloning / 溶血性貧血 / 疾患モデルマウス / 遺伝子治療 / 先天代謝異常 / 転写調節 / 細胞特量的発現 / 遺伝子変異 / 細胞特異的発現 / 遺伝病 / 代謝異常 / Genetic disease / Metabolic disorder / Transgenic mice / Gene therapy / Transcriptional regulation / Hemolytic anemia / Erythroenzymopathies / フルクトース / L型ピルビン酸キナーゼ / 遺伝子発現の調節 / ピルビン酸キナーゼL遺伝子 / Fructose-L-type pyruvate kinase / Regulation of gene expression / 動脈硬化 / 糖尿病 / 低比重リポ蛋白(LDL) / 変性LDL / アポリポ蛋白B / 低ベ-タリポ蛋白血症 / 遺伝子解析 / シトステロ-ル血症 / 動脈硬化症 / LDL / 培養細胞 / アポBイソ蛋白 / 低βリポ蛋白血症 / 変性リポ蛋白 / マクロファージ / LDL pathway / アポB isoform / 低Bリポ蛋白血症 / アポB100 / アポB48 / LDL path way / Atherosclerosis / Diabetes mellitus / Low density lipoproteins(LDL) / Denatured LDL / Apolipoprotein B / Hypobetalipoproteinemia / Gene analysis / Sitosterolemia / 律速酵素 / ホスホフルクトキナ-ゼ / グリコ-ゲン病VII型 / 遺伝子クロ-ニング / cDNAクロ-ニング / スプライシング / 遺伝子構造 / ホスホフルクトキナーゼ欠損症(グリコーゲン病VII型) / cDNAクローニング / 一次構造 / 異常遺伝子 / Key enzyme / Phosphofructokinase / Type VII glycogenosis / Genomic cloning / cDNA cloning / Splicing / Genomic structure / ピルビン酸キナ-ゼアイソザイム / CATアッセイ / 肝特異的転写因子 / シス作用制御領域 / Pyruvate kinase isozymes / Tissue-specific expression / Cis-acting element / CAT assay / Enhancer / Hepatocyte-specific transcription factor
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Research Projects
(
27
results)
Co-Researchers
(
27
People)
Project Start Year (Newest)
Project Start Year (Oldest)
Elucidation of glucose responsive transcription factor complexes of L-type pyruvate kinase gene
Principal Investigator
Principal Investigator
NOGUCHI Tamio
Project Period (FY)
2006 – 2007
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Food science
Research Institution
Otani Womens University
非受容体型転写因子の活性を制御する食品成分の検索
Principal Investigator
Principal Investigator
野口 民夫
Project Period (FY)
2003 – 2004
Research Category
Grant-in-Aid for Exploratory Research
Research Field
Food science
Research Institution
Nagoya University
Molecular mechanism of transcriptional regulation of pyruvate kinase gene by glucose and insulin
Principal Investigator
Principal Investigator
NOGUCHI Tamio
Project Period (FY)
2002 – 2004
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
食品科学・栄養科学
Research Institution
Nagoya University
肝細胞の発生と分化を司る遺伝子システムにおけるHexの役割の解明
Principal Investigator
Principal Investigator
野口 民夫
Project Period (FY)
2000
Research Category
Grant-in-Aid for Scientific Research on Priority Areas (C)
Review Section
Biological Sciences
Research Institution
Nagoya University
Regulation of enzyme activity and gene expression of pyruvate kinase by dietary factors
Principal Investigator
Principal Investigator
NOGUCHI Tamio
Project Period (FY)
1999 – 2001
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
食品科学・栄養科学
Research Institution
Nagoya University
Regulation of transcription and splicing of pyruvate kinase isozyme genes
Principal Investigator
Principal Investigator
NOGUCHI Tamio
Project Period (FY)
1997 – 1998
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
General medical chemistry
Research Institution
Nagoya University
福井医科大学
Regulation of human pyruvate kinase gene in red cells
Principal Investigator
KANNO Hitoshi
Project Period (FY)
1997 – 1998
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Pathological medical chemistry
Research Institution
Okinaka Memorial Institute for Medical Research
ピルビン酸キナーゼアイソザイム遺伝子の転写とスプライシングを制御する因子
Principal Investigator
Principal Investigator
野口 民夫
Project Period (FY)
1996
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
General medical chemistry
Research Institution
福井医科大学
Functional and physiological analysis of plechstrin homology domain structure
Principal Investigator
INAZU Tetsuya
Project Period (FY)
1995 – 1996
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Pathological medical chemistry
Research Institution
Fukui Medical School
L型ピルビン酸キナーゼ遺伝子のエンハンサーユニットに結合する転写因子の構造と機能
Principal Investigator
Principal Investigator
野口 民夫
Project Period (FY)
1994
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
General medical chemistry
Research Institution
Osaka University
インスリンによる転写調節の分子機構とその異常
Principal Investigator
Principal Investigator
野口 民夫
Project Period (FY)
1993
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Pathological medical chemistry
Research Institution
Osaka University
肝癌におけるピルビン酸キナ-ゼアイソザイムの遺伝子発現を制御する因子
Principal Investigator
田中 武彦
Project Period (FY)
1991
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Osaka University
Molecular mechanism of transcriptional regulation by insulin
Principal Investigator
Principal Investigator
NOGUCHI Tamio
Project Period (FY)
1991 – 1992
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
General medical chemistry
Research Institution
Osaka University
肝発癌過程のマ-カ-酵素の特異的発現機構と機能の解明
Principal Investigator
佐藤 清美
Project Period (FY)
1990
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Hirosaki University
肝癌におけるピルビン酸キナ-ゼアイソザイムの遺伝子発現を制御する因子
Principal Investigator
TANAKA Takehiko
Project Period (FY)
1990
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Osaka University
肝化学発癌過程の前癌細胞における遺伝子および遺伝子発現の異常の解析
Principal Investigator
佐藤 清美
Project Period (FY)
1989
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Hirosaki University
Cis-Acting and Trans-Acting Elements that Regulate Tissue-Specific Gene Expression
Principal Investigator
Principal Investigator
NOGUCHI Tamio
Project Period (FY)
1989 – 1990
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
General medical chemistry
Research Institution
Osaka University
肝化学発癌過程の前癌細胞における遺伝子および遺伝子発現の異常の解析
Principal Investigator
佐藤 清美
Project Period (FY)
1988
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Hirosaki University
Molecular biological investigation into the enzyme abnormality in muscle phosphofructokinase deficiency
Principal Investigator
TARUI Seiichiro
Project Period (FY)
1988 – 1989
Research Category
Grant-in-Aid for General Scientific Research (A)
Research Field
内分泌・代謝学
Research Institution
Osaka University Medical School
Regulatory mechanisms of gene expression of pyruvate kinase isozymes
Principal Investigator
TANAKA Takehiko
Project Period (FY)
1988 – 1989
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
General medical chemistry
Research Institution
Osaka University
肝化学発癌過程の前癌細胞における遺伝子および遺伝子発現の異常の解析
Principal Investigator
佐藤 清美
Project Period (FY)
1987
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Hokkaido University
癌遺伝子の発現とアイソザイムの偏倚
Principal Investigator
田中 武彦
Project Period (FY)
1987 – 1988
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Osaka University
Factors responsible for tissue-specific gene expression
Principal Investigator
Principal Investigator
NOGUCHI Tamio
Project Period (FY)
1987 – 1988
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
General medical chemistry
Research Institution
Osaka University
癌遺伝子の発現とアイソザイムの偏倚
Principal Investigator
田中 武彦
Project Period (FY)
1986
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Osaka University
プロセシングの違いによるピルビン酸キナーゼアイソザイムのmRNAの生成とその調節
Principal Investigator
Principal Investigator
野口 民夫
Project Period (FY)
1986
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
General medical chemistry
Research Institution
Osaka University
Analysis of abnormal LDL metabolism and gene analysis of apolipoprotein B
Principal Investigator
SHIGETA Yukio
Project Period (FY)
1986 – 1989
Research Category
Grant-in-Aid for General Scientific Research (A)
Research Field
内分泌・代謝学
Research Institution
Shiga University of Medical Science
Regulatory mechanisms of gene expression of hepatic enzyme by insulin and fructose
Principal Investigator
TANAKA Takehiko
Project Period (FY)
1985 – 1986
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
代謝生物化学
Research Institution
Osaka University
# of Projects (Dsc)
# of Projects (Asc)
1.
TANAKA Takehiko
(60028272)
# of Collaborated Projects:
6 results
# of Collaborated Products:
0 results
2.
佐藤 清美
(50006079)
# of Collaborated Projects:
4 results
# of Collaborated Products:
0 results
3.
村松 正實
(10035454)
# of Collaborated Projects:
4 results
# of Collaborated Products:
0 results
4.
津田 洋幸
(10163809)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
5.
渡部 烈
(00057316)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
6.
INAZU Tetsuya
(00242587)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
7.
YAMADA Kazuya
(20263238)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
8.
菊池 九二三
(20006117)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
9.
林 健志
(00019671)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
10.
宮城 妙子
(50006110)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
11.
谷口 直之
(90002188)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
12.
今井 圓裕
(00223305)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
13.
立木 蔚
(90006065)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
14.
MARUYAMA Shingo
(90262633)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
15.
KANNO Hitoshi
(70221207)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
16.
KOIZUMI Tsutomu
(40126579)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
17.
MIWA Shiro
(40034954)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
18.
岡田 統子
(70303584)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
19.
SHIGETA Yukio
(60028321)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
20.
KOSUGI Keisuke
(00153544)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
21.
HIDAKA Hideki
(80156603)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
22.
KASHIWAGI Atsunori
(20127210)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
23.
HARANO Yutaka
(10028615)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
24.
TARUI Seiichiro
(00028341)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
25.
SHIMIZU Takao
(40206199)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
26.
KUWAJIMA Masamichi
(00205262)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
27.
KONO Norio
(30093412)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
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