NAKANISHI Toyofumi 中西豊文

… Alternative Names

NAKANISHI TOYOFUMI 中西豊文

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Researcher Number	10247843
Other IDs
Affiliation (Current)	2025: 修文大学, 医療科学部, 教授
Affiliation (based on the past Project Information) *help	2021: 大阪医科薬科大学, 研究支援センター, 准教授 2019 – 2020: 大阪医科大学, 研究支援センター, 准教授 2007 – 2015: Osaka Medical College, 医学部, 准教授 2014: 大阪医科大学, 医学部 2008: 大阪医科大学, 臨床検査医学教室, 准教授 … More 2004 – 2006: 大阪医科大学, 医学部, 助教授 1996 – 2003: 大阪医科大学, 医学部, 講師 1997: 大阪医科大学, 医学部, 構師 1994 – 1995: 大阪医科大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Laboratory medicine / Laboratory medicine / Basic Section 52010:General internal medicine-related / オミクス計測科学 Except Principal Investigator Laboratory medicine / Laboratory medicine / Experimental pathology / Physical pharmacy / Metabolomics / Digestive surgery
Keywords	Principal Investigator 自己抗体 / Diagnosis / Biomarker / Adenocarcinoma / Proteomics / Cancer / Autoantibody / PEDF / 質量イメージング / 神経変性疾患 … More / 検査診断法 / ネオ抗原ペプチド / 変異トリオースリン酸イソメラーゼ / 膵臓癌特異抗原 / ELISA法 / トリオースリン酸イソメラーぜ / 膵臓癌得意抗原 / スクリーニング / ネオ抗原 / 検査診断技術 / 自己抗体スクリーニング / 特異抗原 / 膵臓癌診断マーカー / ペルオキシレドキシン-6 / α-エノラーゼ / 2D-PAGE / 肺癌バイオマーカー / 肺アデノカルシノーマ / 癌プロテオミクス / Ion-trap MS / Vitreous humor / Angiogenesis-modulated factor / Diabetic Retinopathy / Expression Proteomics / ソフトイオン化質量分析 / イオントラップ型質量分析計 / 硝子体 / 血管新生制御因子 / 糖尿病性網膜症 / 発現プロテオミクス / Neurodegenerative disease / Free cooper ion / Active oxide species / Cooper-binding protein / Oxidative stress in the body / Holo / Ration of Apo / NanoESIMS method / 遊離銅イオン毒性 / ホロ型 / 銅イオン毒性 / 活性酸素種 / 銅結合金属蛋白 / 細胞内酸化的ストレス / ホロ型比 / アポ型 / ナノESIMS法 / トランスサイレチン / アミロイド原性 / 補助的病理診断 / コンゴレッド染色性 / 沈着分子 / アミロイドーシス / アミロイド原性獲得 / 凝集体形成 / ラジカル反応 / アミロイド / 患者自己抗体 / L-Plastin / プロテオーム解析 / 造血器系疾患 / 癌患者自己抗体 / 癌特異マーカー / L-plastin / 非ホジキンリンパ腫 / Autoantibodiomics / 完全分子 / アミノ酸配列 / ナノLC / 自家製ミクロキャピラリーカラム / 超高感度分析 / 新規変異種 / 正常型比 / 変異型 / 亜鉛-SOD / 銅 / 免疫沈降物 / エレクトロスプレーイオン化質量分析 / 固定化酵素 / アダクト分子 / 異常Hb症 / ナノスプレー手法 / エレクトロスプレーイオン化質量分析法 … More Except Principal Investigator 質量分析 / トランスサイレチン / HCV / mass spectrometry / クリオグロブリン / プロテオミクス / プロテオーム / 自己抗体 / MALDI-TOFMS / SDS-PAGE / エレクトロスプレイ / 蛋白質修飾構造 / cold activation / RF / MS / ESI / HPLC / HbAlc / HCV感染 / cryoglobulin / rheumatoid factor / 補体 / コールドアクチベーション / リウマチ因子 / 補体寒冷活性化 / C型肝炎 / プロテオーム解析 / アミロイドーシス / 亜硫酸化 / 免疫沈降法 / 翻訳後修飾 / immunoblotting / immunoprecipitation / electrophoresis / proteome / autoantibody / Behecet's disease / Behcet病 / 二次元電気泳動 / 免疫プロッティング / 免疫沈降 / 電気泳動 / ベーチェット病 / β-elimination / S-sulfocysteine / dehydroalanine / glycine / cysteine / transthyretin (TTR) / 非共有結合ポリマー / アミロイド変性 / SDS-PAGE解析 / β脱離 / 亜硫酸システイン / デヒドロアラニン / グリシン / システイン / トランスサイレチン(TTR) / Molybdenum cofactor deficiency / Homocysteine / Immunoprecipitation / Electrospray / Mass Spectrometry / Transthyretin / Sulfite Oxidase / Modified Protein / モリブデン補因子欠損症 / ホモシステイン / 質料分析 / proteomics / cold complent activation / immunoglobulin V regeon / complement / アルコール長期多飲者 / HCV感染B細胞 / 補体価 / エレクトロスプレーイオン化質量分析 / ビアコア / Ga抗原エピトープ / 慢性関節リウマチ / 生殖細胞型遺伝子 / 体細胞高頻度突然変異 / 補体cold activation / 低温補体活性化現象 / 免疫グロブリンV領域 / Glu-C / immunoassays / abnormal Hb / electrospray ionization / カルバミルHb / β鎖糖化成分 / 方法間誤差 / カルボキシ末端アルギニン欠損Hb / ホルミルHb / V8プロテアーゼ / 異常Hb / 液体クロマトグラフィー / 糖化ヘモグロビン / 固相化酵素 / デイテクターゲイン / 蛋白分解酵素 / 国際標準測定法 / ESI-MS / 標準法 / 精度管理 / 異常ヘモグロビン / 糖化ペプチド / 糖尿病 / HbA1c / IL-2 receptor / non-Hodgkin's lymphoma / liver cirrhosis / HCV intection / cold acfivation(CA) / complement CH50 / 非ホジキンリンパ腫 / 可溶性IL-2レセプター / リウマトイド因子 / cold activation (CA) / 肝硬変 / アルコール多飲者 / アルコール性肝障害 / 肝障害進展 / cold activation(CA) / 補体価CH50 / chronic hepatitis / lymphocyte / complement cold activatiomn / complement activation in vitro / immune complex / hepatitis C virus / 抗体の親和性 / 抗原特異性 / Rf / C4 / 補体低温活性化 / CH50 / ゴールドアクチベーション / 酸化修飾蛋白質 / 酸化ストレス / ダウン症 / 関節炎 / 質量イメージング / 関節リウマチ / TOF/TOF / 毛髪分析 / イメージング / 乱用薬物 / 毛髪 / 膵臓癌特異抗原 / 核内タンパク質 / 細胞膜 / Candidate marker / Triosephosphate isomerase / Pancreatic cancer / Autoantibodiomics / 細胞膜/核内タンパク質 / 膵臓癌 / マウス肝臓切片 / 脳前頭葉切片 / ImagingMS / アミロイド斑 / S-sulfonation / TTR由来アミロイドーシス / 脳神経疾患 / 痴呆 / タンパク質 / 神経科学 / バイオマーカー / 間質性肺炎 / 皮膚筋炎 / タンパク質間相互作用分析 / インスリン様物質 / 劇症1型糖尿病 / インスリン / 血清 / 生体分子 / 劇症1型糖尿病、、、、 / PANC-1 / 膵癌特異抗原 / 老年性 / 家族性 / 修飾構造 / モリブデン補因子欠損症候群 / アミロイド原性 / アミロイドポリニューロパチー / 亜硫酸塩 / 老年性全身性アミロイドーシス / 家族性アミロイドポリニューロパチー Less

Identifications of pancreatic cancer specific neo-antigens with the autoantibodiomics and verifications of diagnostic utilities of its autoantibody screening to neo-antigensPrincipal Investigator
- Principal Investigator
  
  NAKANISHI TOYOFUMI
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Osaka Medical and Pharmaceutical University
Identifications of abnormal modified proteins localized in amyloid tissues by MALDI-imaging and clarification of formation of amyloid fibrilPrincipal Investigator
- Principal Investigator
  
  Nakanishi Toyofumi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  オミクス計測科学
- Research Institution
  Osaka Medical College
Mass spectrometry imaging of single hair specimens for the reliable chronological estimation of drug abuse, and for the investigation of the mechanism of drug incorporation into hair
- Principal Investigator
  
  TSUCHIHASHI Hitoshi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Osaka Medical College
Profile analysis of disease-related markers in synovial tissues of rheumatoid arthritis using imaging mass spectrometry
- Principal Investigator
  
  TAKEUCHI Tooru
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Osaka Medical College
Search of oxidized protein involved in the mechanism of central nervous system impairment of Down syndrome model Ts65Dn mouse
- Principal Investigator
  
  MOTOTADA Shichiri
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Experimental pathology
- Research Institution
  National Institute of Advanced Industrial Science and Technology
Investigation of the molecular mechanism of the radical reaction to induce the amyloid fibril derived from the transthyretinPrincipal Investigator
- Principal Investigator
  
  NAKANISHI Toyofumi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Osaka Medical College
Identifications of tentative pancreatic cancer-related antigens of expressed proteins derived from membrane and nuclei components of 4 pancreatic cancer cell lines by autoantibodiomics
- Principal Investigator
  
  MIYAMOTO Yoshiharu
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Osaka Medical College
Detection of Disease-related Proteins in Dermatomyositis Associated with Interstitial Pneumonia by Proteomics-based Analysis
- Principal Investigator
  
  TAKEUCHI Tooru
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Osaka Medical College
質量顕微鏡によるアミロイド組織内沈着分子プロフィル異常と線維形成阻止法の開発
- Principal Investigator
  
  田窪孝行
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Laboratory medicine
- Research Institution
  Osaka Medical College
Identifications of non-Hodgkin's lymphoma (NHL)-specific antigens bounded with autoantibodies in plasma derived from patients with NHL by an autoantibodiomicsPrincipal Investigator
- Principal Investigator
  
  NAKANISHI Toyofumi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Osaka Medical College
Identify new insulin mimicking molecules from serum of fulminant type 1 diabetes
- Principal Investigator
  
  MISHIBA Yuko
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Metabolomics
- Research Institution
  Osaka Medical College
プロテオミクスによる膵癌特異抗原に対する新規自己抗体の同定
- Principal Investigator
  
  MIYAMOTO Yoshiharu
- Project Period (FY)
  2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Osaka Medical College
Identifications of diagnostic biomarkers specific binding to soluble proteins of adenocarcinoma A 549 cell lines by an autoantibodiomicsPrincipal Investigator
- Principal Investigator
  
  NAKANISHI Toyofumi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Osaka Medical College
Proteomics-based approach identifying autoantibodies in Behcet's disease
- Principal Investigator
  
  TAKEUCHI Toru
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Osaka Medical College
Analysis of modified structures of transthyretin, elucidation of disease etiology of amyloidosis and application to clinical laboratory tests
- Principal Investigator
  
  SHIMIZU Akira
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Osaka Medical College
Elucidation of the fine structure and the generation process of modified proteins (sulfonate, nitroso, et al.) application to clinical laboratory test
- Principal Investigator
  
  SHIMIZU Akira
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Osaka Medical College
Expression proteomics of angiogenesis-modulated factors in human vitreous humors derived from diabetic retinopathyPrincipal Investigator
- Principal Investigator
  
  NAKANISHI Toyofumi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Osaka Medical College
トランスサイレチン関連アミロイドーシスにおける繊維化分子機構の解明
- Principal Investigator
  
  岸川匡彦
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Osaka Medical College
B cell clone proliferated in HCV infection and V regeon structure of RF correlated to complement clod activation
- Principal Investigator
  
  SHIMIZU Akira
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Osaka Medical College
The quantification of ratios between apo to holo types of metal binding protein : a new indicator of the oxidative stress in cellsPrincipal Investigator
- Principal Investigator
  
  NAKANISHI Toyofumi
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Osaka Medical College
神経疾患の原因となる変異蛋白質の質量分析による検出と構造決定および新診断法の確立
- Principal Investigator
  
  KISHIKAWA Masahiko
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Laboratory medicine
- Research Institution
  Osaka Medical College
Establishment and practical use of reference method for glyco-haemoglobin by mass spectrometry
- Principal Investigator
  
  SHIMIZU Akira
- Project Period (FY)
  1997 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Laboratory medicine
- Research Institution
  Osaka Medical College
金被覆ミクロキャピラリーLC装着質量分析による癌特異ペプチドの超高感度構造決定Principal Investigator
- Principal Investigator
  
  中西豊文
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Laboratory medicine
- Research Institution
  Osaka Medical College
Elucidation of complement cold activation and cryoglobulin formation associated with HCV infection.
- Principal Investigator
  
  SHIMIZU Akira
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Osaka Medical College
Study of the mechanism of in-vitro activation of complement and formation of cryoglobulin in the sera from patients with C type hepatitis
- Principal Investigator
  
  SHIMIZU Akira
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Osaka Medical College

[Book] 臨床検査におけるイメージング質量分析（分担）2013
- Author(s)
  中西豊文（丹羽利允、野村文夫編集）
- Total Pages
  6
- Publisher
  診断と治療社
- Data Source
  KAKENHI-PROJECT-25513010
[Book] 臨床材料を用いた MALDI- イメージング解析(第8章:分子イメージングと医療)臨床プロテオーム個別化医療を目指す臨床バイオマーカー探索(日本臨床プロテオーム研究会編加藤治文、中村和行、西尾和人、西村俊秀編)2012
- Author(s)
  中西豊文
- Publisher
  金原出版分担
- Data Source
  KAKENHI-PROJECT-22590540
[Book] A critical study of the isosteres of 10^<th> cysteine residue of transthyretin induced with cysteine-S-sulfonate by ultra-high resolutio mass spectrometry. In : Amyloids : Composition, Functions and Pathology(Irene P.Halcheck and Nancy R.Vernon)2012
- Author(s)
  Nakanishi T, Iwasaki N, Saito K, Yoshioka M, Yamamoto D, Tsuji M, Nirasawa T, Takubo T
- Total Pages
  70
- Publisher
  NOVA Science
- Data Source
  KAKENHI-PROJECT-22590540
[Book] A critical study of the isosteres of 10th cysteine residue of transthyretin induced withcysteine-S-sulfonate by ultra-high resolutio mass spectrometry.2012
- Author(s)
  Nakanishi T, Iwasaki N, Saito K, Yoshioka M, Yamamoto D, Tsuji M, Nirasawa T, Takubo T.
- Publisher
  In: Amyloids: Composition, Functions and Pathology. NOVA Publisher (Irene P. Halcheck and Nancy R. Vernon)
- Data Source
  KAKENHI-PROJECT-22590540
[Journal Article] Identification of nine proteins in whole lung extract derived from bleomycin-induced interstitial pneumonia model mouse by two-dimensional electrophoresis/in-gel digestion/ MALDI-TOF MSMS analysis.2021
- Author(s)
  Ishida T, Kotani T, Tabushi-Matsumura Y, Nakanishi T, Takeuchi T.
- Journal Title
  
  Medical Mass Spectrometry
  
  Volume: 5(1) Pages: 1-9
- NAID
  130008062716
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07928
[Journal Article] Application of MALDI-TOF MS analysis for rapid discrimination of free immunoglobulin light chains, kappa and lambda isotypes in patients with monoclonal immunoglobulin gammopathy.2021
- Author(s)
  Asano S, Masutani R, Ueda K, Igarashi K, Nirasawa T, Kubota M, Tabushi-Matsumura Y, Osaka N, Nakanishi T*
- Journal Title
  
  Medical Mass Spectrometry
  
  Volume: 5(1) Pages: 47-54
- NAID
  130008062720
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07928
[Journal Article] Evaluation of SARS-CoV-2 RNA quantification by RT-LAMP compared to RT-qPCR2021
- Author(s)
  Minami Kenta、Masutani Ryota、Suzuki Youichi、Kubota Meri、Osaka Naofumi、Nakanishi Toyofumi、Nakano Takashi、Ukimura Akira
- Journal Title
  
  Journal of Infection and Chemotherapy
  
  Volume: 27 Issue: 7 Pages: 1068-1071
- DOI
  10.1016/j.jiac.2021.05.004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07596, KAKENHI-PROJECT-19K07928
[Journal Article] 安定同位元素標識体を用いた規格化と定量イメージング2016
- Author(s)
  中西豊文
- Journal Title
  
  質量分析
  
  Volume: 64 Pages: 25-29
- NAID
  130005125538
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25513010
[Journal Article] Time-Course Mass Spectrometry Imaging for Depicting Drug Incorporation into Hair2015
- Author(s)
  Tooru Kamata, Noriaki Shima, Keiko Sasaki, Shuntaro Matsuta, Shiori Takei, Munehiro Katagi, Akihiro Miki, Kei Zaitsu, Toyofumi Nakanishi, Takako Sato, Koichi Suzuki, and Hitoshi Tsuchihashi
- Journal Title
  
  Analytical Chemistry (ACS Publications)
  
  Volume: - Issue: 11 Pages: 5476-5481
- DOI
  10.1021/acs.analchem.5b00971
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24590065, KAKENHI-PROJECT-25513010
[Journal Article] MALDI-TOF/MSによる感染症起因菌の迅速同定2015
- Author(s)
  中西豊文
- Journal Title
  
  臨床病理　63(4) 465-471, 2015
  
  Volume: 63 Pages: 465-471
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25513010
[Journal Article] Single-hair analysis of zolpidem on the supposition of its single administration in drug-facilitated crimes2015
- Author(s)
  Shima N, Sasaki K, Kamata T, Matsuta S, Katagi M, Miki A, Zaitsu K, Sato T, Nakanishi T, Tsuchihashi H, Suzuki K.
- Journal Title
  
  Forensic Toxicol.
  
  Volume: 33 Pages: 122-130
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25513010
[Journal Article] MALDI-TOFMSによる微生物由来r16S関連因子解析と感染症迅速診断2015
- Author(s)
  中西豊文
- Journal Title
  
  外来小児科
  
  Volume: 18 Pages: 171-177
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25513010
[Journal Article] 質量分析法による医学応用研究2014
- Author(s)
  佐藤七夕子、中西豊文
- Journal Title
  
  大阪医科大学雑誌
  
  Volume: 72 Pages: 103-112
- NAID
  40019958232
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25513010
[Journal Article] Quantitative mass barcode-like image of nicotine on single longitudinally sliced hair sections of long-term smokers by matrix-assisted laser desorption time-of-flight mass spectrometry imaging2014
- Author(s)
  Nakanishi T*, Nirasawa T, Takubo T
- Journal Title
  
  J. Anal.Toxicolog.
  
  Volume: 38 Issue: 6 Pages: 349-353
- DOI
  10.1093/jat/bku032
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25513010
[Journal Article] Lung Nocardia elegans Infection Diagnosed on Matrix-assisted Laser Desorption Ionization-time of Flight Mass Spectrometry (MALDI-TOF MS)2014
- Author(s)
  Y.Ooi, H.Shiba, K.Naga, T.Higashiyama, T.Nakanishi, T.Nakano, A.Ukimura and T.Gonoi
- Journal Title
  
  Internal Medicine
  
  Volume: 53 Pages: 2111-2113
- NAID
  130004687653
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25513010
[Journal Article] Clustering and topology of proteins expressed in a single sliced human retina tissue section by MALDI-MS imaging and MS/MS analysis2014
- Author(s)
  Sato N, Nakanishi T*, Nirasawa T, Uchiyama K, Takubo T, Caprioli RM
- Journal Title
  
  Bulletin of the Osaka Medical College
  
  Volume: 60 Pages: 35-39
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25513010
[Journal Article] Significance of the vascular concentration of angiontensin II receptor blockers on the mechanism of lowering blood pressure in spontaneously hypertensive rats.2013
- Author(s)
  Takai S, Jin D, Sakonjo H, Takubo T, Nakanishi T.
- Journal Title
  
  J. Pharmacolog. Sci.
  
  Volume: 123(4) Pages: 371-379
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25513010
[Journal Article] Quantification of candesartan in mouse plasma by MALDI-TOFMS and in tissue sections by MALDI-imaging using the stable-isotope dilution technique.2013
- Author(s)
  Nakanishi T*, Takai S, Jin D, Takubo T.
- Journal Title
  
  Mass Spectrometry(Tokyo)
  
  Volume: 2
- NAID
  10031189344
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25513010
[Journal Article] Topologies of amyloidogenic proteins in Congo red-positive sliced sections of formalin-fixed paraffin embedded tissues by MALDI-MS imaging coupled with on-tissue tryptic digestion.2013
- Author(s)
  Nakanishi T,* Ito M, Nirasawa T, Tsuji M, Takubo T.
- Journal Title
  
  Clin. Biochem.
  
  Volume: 46 Pages: 1595-1600
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25513010
[Journal Article] 組織学的薬物動態解析の重要性2013
- Author(s)
  高井真司、金徳男、田窪孝行、中西豊文
- Journal Title
  
  臨床化学
  
  Volume: 42(4) Pages: 317-323
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25513010
[Journal Article] A critical study of the isosteres of 10th cysteine residue of transthyretin induced with cysteine-S-sulfonate by ultra-high resolutio mass spectrometry.2012
- Author(s)
  Nakanishi T, Iwasaki N, Saito K, Yoshioka M, Yamamoto D, Tsuji M, Nirasawa T, Takubo T.
- Journal Title
  
  In: Amyloids: Composition, Functions and Pathology
  
  Volume: 無し Pages: 165-176
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590540
[Journal Article] Identification of beta-tubulin as a common immunogen in gastrointestinal malignancy by mass spectrometry of colorectal cancer proteome2012
- Author(s)
  Bouras G, Nakanishi T, Fujita Y, Tsunemi S, Takubo T, Tanigawa N.
- Journal Title
  
  Implications for early disease detection. Anal & Bioanal. Chem.
  
  Volume: 403(7) Pages: 1801-1809
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590540
[Journal Article] ホルマリン固定パラフィン包埋組織切片/剥離毛髪を用いた MALDI イメージング解析とその応用研究2012
- Author(s)
  中西豊文、伊藤美奈子、上田一仁、和田晋一、藤岡重和、辻求、田窪孝行新鮮凍結/
- Journal Title
  
  臨床病理
  
  Volume: 60 Pages: 125-30
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590540
[Journal Article] 新鮮凍結/ホルマリン固定パラフィン包埋組織切片/剥離毛髪を用いたMALDIイメージング解析とその応用研究2012
- Author(s)
  中西豊文、伊藤美奈子、上田一仁、和田晋一、藤岡重和、辻求、田窪孝行
- Journal Title
  
  臨床病理
  
  Volume: 60 Pages: 125-30
- NAID
  10030463131
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590540
[Journal Article] S-sulfonation of transthyretin is an important trigger step in the formation of transthyretin-related amyloid fibril.2012
- Author(s)
  Nakanishi T, Yoshioka M, Moriuchi K, Yamamoto D, Tsuji M, Takubo T.
- Journal Title
  
  Biochim.Biophys Acta
  
  Volume: 1804 Pages: 1449-1456
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590540
[Journal Article] 新鮮凍結/ホルマリン固定パラフィン包埋組織切片/剥離毛髪を用いた MALDI イメージング解析とその応用研究　第 54 回近畿支部総会シンポジウム:次世代臨床査法開発の最前線(2)2012
- Author(s)
  中西豊文、伊藤美奈子、上田一仁、和田晋一、藤岡重和、辻　求、田窪孝行
- Journal Title
  
  臨床病理
  
  Volume: 60 Pages: 125-130
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590540
[Journal Article] MALDI-イメージングによる臨床病理診断の試みとその課題点／将来展望2012
- Author(s)
  中西豊文
- Journal Title
  
  臨床化学
  
  Volume: 41 Pages: 270-271
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590540
[Journal Article] MALDI-TOF and MALDI-FTICR imaging mass spectrometry of methamphetamine incorporated into hair.2011
- Author(s)
  Miki A, Katagi M, Kamata T, Zaitsu K, Tatsuno M, Nakanishi T, Tsuchihashi H, Takubo T, Suzuki K.
- Journal Title
  
  J.Mass Spectrom.
  
  Volume: 46(4) Pages: 411-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590540
[Journal Article] MALDI-TOF and MALDI-FTICR imaging mass spectrometry of methamphetamine incorporated into hair2011
- Author(s)
  Miki A, Katagi M, Kamata T, Zaitsu K, Tatsuno M, Nakanishi T, Tsuchihashi H, Takubo T, Suzuki K.
- Journal Title
  
  J. Mass Spectrom.
  
  Volume: 46(4) Pages: 411-6
- Data Source
  KAKENHI-PROJECT-21590642
[Journal Article] Imaging of methamphetamine incorporatedinto hair using matrix-assisted laser desorption/ionization time-of-flight imaging mass spectrometry.2011
- Author(s)
  Miki A, Katagi M, Shima N, Kamata T,Tatsuno M, Nakanishi T, Tsuchihashi H, Takubo T, Suzuki K.
- Journal Title
  
  Forensic Tox.
  
  Volume: 29 Pages: 111-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590540
[Journal Article] Imaging of methamphetamine incorporated into hair using matrix-assisted laser desorption/ionization time-of-flight imaging mass spectrometry2011
- Author(s)
  Miki A, Katagi M, Shima N, Kamata T, Tatsuno M, Nakanishi T, Tsuchihashi H, Takubo T, Suzuki K.
- Journal Title
  
  Forensic Tox
  
  Volume: 29 Pages: 111-6
- Data Source
  KAKENHI-PROJECT-21590642
[Journal Article] S-sulfonation of transthyretin is an important trigger step in the formation of transthyretin-related amyloid fibril.2010
- Author(s)
  Nakanishi T, Yoshioka M, Moriuchi K, Yamamoto D, Tsuji M, Takubo T.
- Journal Title
  
  Biochim.Biophys Acta.
  
  Volume: 1804(4) Pages: 1449-56
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590540
[Journal Article] S-sulfonation of transthyretin is animportant trigger step in the formation of transthyretin-related amyloid fibril. Biochim.2010
- Author(s)
  Nakanishi T, Yoshioka M, Moriuchi K, Yamamoto D, Tsuji M, Takubo T.
- Journal Title
  
  Biophys Acta.
  
  Volume: 1804(4) Pages: 1449-56
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590540
[Journal Article] S-sulfonation of transthyretin is an important trigger step in the formation of transthyretin-related amyloid fibril2010
- Author(s)
  Nakanishi T, Yoshioka M, Moriuchi K, Yamamoto D, Tsuji M, Takubo T.
- Journal Title
  
  Biochim. Biophys Acta
  
  Volume: 1804(4) Pages: 1449-56
- Data Source
  KAKENHI-PROJECT-21590642
[Journal Article] Proteomics-based identification of a tumor associated antigen and its corresponding autoantibody in gastric cancer.2010
- Author(s)
  Tunemi S, Nakanishi T, Fujita Y, Bouras G, Miyamoto Y, Miyamoto A, Sakai A, Noumra E, Takubo T, Tanigawa N.
- Journal Title
  
  Oncology Reports.
  
  Volume: 23 Pages: 949-56
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590540
[Journal Article] Proteomics-based identification of a tumor associated antigen and its corresponding autoantibody in gastric cancer2010
- Author(s)
  Tunemi S, Nakanishi T, Fujita Y, Bouras G, Miyamoto Y, Miyamoto A, Sakai A, Noumra E, Takubo T, Tanigawa N.
- Journal Title
  
  Oncology Reports
  
  Volume: 23 Pages: 949-56
- Data Source
  KAKENHI-PROJECT-21590642
[Journal Article] MSイメージングによる組織内発現タンパク質の局在性、量的・質的解析と医学応用2009
- Author(s)
  中西豊文
- Journal Title
  
  大阪医科大学雑誌 68(2)
  
  Pages: 64-65
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20659093
[Journal Article] 自己抗体を標的にした癌マーカー検索(Autoantibodimics)2008
- Author(s)
  中西豊文、清水章、田伏洋子、田窪孝行
- Journal Title
  
  生物物理化学 52
  
  Pages: 35-38
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590574
[Journal Article] Identification of phosphotyrosyl proteins in vitreous humors of patients with vitreoretinal diseases by sodium dodecyl-sulfatepolyacrylamide gel electrophoresis/western blotting/matrix-assisted laser desorption time-of-flight mass spectrometry2008
- Author(s)
  N. Mukai, T. Nakanishi, A. Shimizu, T. Takubo, T. Ikeda
- Journal Title
  
  Ann Clin Biochem 45(3)
  
  Pages: 307-312
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590574
[Journal Article] Detection of citrullinated proteins in synovial fluids derived from patients with rheumatoid arthritis by proteomics-based analysis2008
- Author(s)
  Y. Tabushi, T. Nakanishi, T. Takeuchi, M. Nakajima, K. Ueda, T. Kotani, S. Makino, A. Shimizu, T. Hanafusa, T. Takubo
- Journal Title
  
  Ann Clin Biochem 45(4)
  
  Pages: 413-417
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590574
[Journal Article] Identification of L-plastin autoantibody in plasma of patients with non-Hodgkin's lymphoma using a proteomies-based analysis2008
- Author(s)
  Ueda K, Nakanishi T.Shimizu A, Takubo T, Matsuura N.
- Journal Title
  
  Ann Clin Biochem 45
  
  Pages: 65-69
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590574
[Journal Article] Proteomics-based identification of autoantibody against heat shock protein 70 as a diagnostic marker in esophageal squamous cell carcinoma2008
- Author(s)
  Y. Fujita, T. Nakanishi, Y. Miyamoto, M. Hiramatsu, H. Mabuchi, A. Miyamoto, A. Shimizu, N. Tanigawa
- Journal Title
  
  Cancer Letters 263(2)
  
  Pages: 280-90
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590574
[Journal Article] Identification of L-plastin autoantibody in plasma of patients with non-Hodgkin' s lymphoma using a proteomics-based analysis2008
- Author(s)
  Ueda K, Nakanishi T, Shimizu A, Takubo T, Matsuura N.
- Journal Title
  
  Ann Clin Biochem 45(1)
  
  Pages: 65-69
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590574
[Journal Article] Detection of eight antibodies in cancer patients' sera against proteins derived from the adenocarcinoma A549 cell line using proteomics-based analysis.2006
- Author(s)
  Nakanishi T, Takeuchi T, Ueda K, Murao H, Shimizu A.
- Journal Title
  
  J Chromatogr B Analyt Technol Biomed Life Sci 838(1)
  
  Pages: 15-20
- NAID
  10025784546
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590501
[Journal Article] Detection of eight antibodies in cancer patients' sera against proteins derived from the adenocarcinoma A549 cell line using proteomics-based analysis.2006
- Author(s)
  Nakanishi T, Takeuchi T, Ueda K, Murao H, Shimizu A
- Journal Title
  
  J Chromatogr B Analyt Technol Biomed Life Sci 838・1
  
  Pages: 15-20
- NAID
  10025784546
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590501
[Journal Article] Proteomics-Based Approach Identifying Autoantibody against Peroxiredoxin VI as a Novel SerumMarker in Esophageal Squamous Cell Carcinoma2006
- Author(s)
  Yoshihisa Fujita, Toyofumi Nakanishi, Masako Hiramatsu, Hideaki Mabuchi, Yoshiharu Miyamoto, Akiko Miyamoto, Akira Shimizu, Kyoichi Takaori, Nobuhiko Tanigawa
- Journal Title
  
  Clinical Cancer Research 12・21 (In press)
- Data Source
  KAKENHI-PROJECT-18591530
[Journal Article] Proteomic-based approach identifying autoantibody against peroxiredoxin IV as a novel serum marker in esophageal squamous cell carcinoma.2006
- Author(s)
  Fujita Y, Nakanishi T, Hiramatsu M, Mabuchi H, Miyamoto Y, Miyamoto A, Shimizu A, Tanigawa N.
- Journal Title
  
  Clin.Cancer Res. 12・21
  
  Pages: 6415-6420
- Data Source
  KAKENHI-PROJECT-17590501
[Journal Article] Proteomics-based approach identifying autoantibody against peroxiredoxin VI as a novel serum marker in esophageal squamous cell carcinoma2006
- Author(s)
  Fujita Y, Nakanishi T, et al.
- Journal Title
  
  Clin Cancer Res 12
  
  Pages: 6415-6415
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590502
[Journal Article] Proteomics-based discovery of α-enolase autoantibody in sera of lung adenocarcinoma2006
- Author(s)
  Nakanishi T, Takeuchi T, et al.
- Journal Title
  
  Proceedings of 53th ASMS conference on mass spectrometry and allied topics
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590502
[Journal Article] Proteomics-based approach identifying autoantibody against peroxiredoxin VI as a novel serum marker in esophageal squamous cell carcinoma.2006
- Author(s)
  Fujita Y, Nakanishi T, et al.
- Journal Title
  
  Clin Cancer Res. 12
  
  Pages: 6415-6420
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590502
[Journal Article] Proteomic-based approach identifying autoantibody against peroxiredoxin VI as a novel serum marker in esophageal squamous cell carcinoma.2006
- Author(s)
  Fujita Y, Nakanishi T, Hiramatsu M, Mabuchi H, Miyamoto Y, Miyamoto A, Shimizu A, Tanigawa N.
- Journal Title
  
  Clin.Cancer Res. 12(21)
  
  Pages: 6415-6420
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590501
[Journal Article] Detection of eight antibodies in cancer patients' sera against proteins derived from the adenocarcinoma A549 cell line using proteomics-based analysis.2006
- Author(s)
  Nakanishi T
- Journal Title
  
  J Chromatogr B 838・1
  
  Pages: 15-20
- NAID
  10025784546
- Data Source
  KAKENHI-PROJECT-17590502
[Journal Article] Detection of eight antibodies in cancer patients' sera against proteins derived from the adenocarcinoma A549 cell line using proteomics-based analysis.2006
- Author(s)
  Nakanishi T, Takeuchi T, et al.
- Journal Title
  
  J Chromatogr B 838
  
  Pages: 15-15
- NAID
  10025784546
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590502
[Journal Article] Proteomic-based approach identifying autoantibody against peroxiredoxin VI as a novel serum marker in esophageal squamous cell carcinoma.2006
- Author(s)
  Fujita Y, Nakanishi T, Hiramatsu M, Mabuchi H, Miyamoto Y, Miyamoto A, Shimizu A, Tanigawa N
- Journal Title
  
  Clin. Cancer Res. 12・21
  
  Pages: 6415-6420
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590501
[Journal Article] Detection of eight antibodies in cancer patients' sera against proteins derived from the adenocarcinoma A549 cell line using proteomics-based analysis.2006
- Author(s)
  Nakanishi T, Takeuchi T, Ueda K, Murao H, Shimizu A.
- Journal Title
  
  J Chromatogr B 838
  
  Pages: 15-20
- NAID
  10025784546
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590502
[Journal Article] Detection and characterization of variant and modified structures of proteins in blood and tissues by mass spectrometry.2006
- Author(s)
  Shimizu A, Nakanishi T, Miyazaki A.
- Journal Title
  
  Mass Spectrom Rev. 25
  
  Pages: 686-712
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590502
[Journal Article] Detection and characterization of variant and modified structures of proteins in blood and tissues by mass spectrometry.2006
- Author(s)
  Shimizu A, Nakanishi T, et al.
- Journal Title
  
  Mass Spectrom Rev 25
  
  Pages: 686-686
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590502
[Journal Article] Proteomics-based discovery of -enolase autoantibody in sera of lung adenocarcinoma.2005
- Author(s)
  Nakanishi T
- Journal Title
  
  Proceediings of 53th ASMS conference on mass spectrometry and allied topics
- Data Source
  KAKENHI-PROJECT-17590502
[Journal Article] Hb KOCHI[β141(H19)Leu→Val (g.1404 C→G) ; 144-146(HC1-3)Lys-Tyr-His→0(g.1413 A→T)] :A NEW VARIANT WITH INCREASED OXYGEN AFFINITY.2005
- Author(s)
  A Miyzai, T Nakanishi, A Shimizu, M Mizobuchi, Y Yamada, K Imai
- Journal Title
  
  Hemoglobin 29・1
  
  Pages: 1-10
- Data Source
  KAKENHI-PROJECT-16590466
[Journal Article] Hb KOCHI [β141(H19)Leu→Val (g.1404 C→G) ; 144-146(HC1-3)Lys-Tyr-His→0 (g.1413 A→T)] : A NEW VARIANT WITH INCREASED OXYGEN AFFINITY.2005
- Author(s)
  A Miyazaki, T Nakanishi, A Shimizu, M Mizobuchi, Y Yamada, K Imai
- Journal Title
  
  Hemoglobin 29(1)
  
  Pages: 1-10
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590466
[Journal Article] Hb KOCHI [β141(H19)Leu→Val (g.1404 C→G);144-146(HC1-3)Lys-Tyr-His→0(g.1413 A→T)]:A NEW VARIANT WITH INCREASED OXYGEN AFFINITY.2005
- Author(s)
  Ayako Miyazaki, Toyofumi Nakanishi, Akira Shimizu, Miki Mizobuchi, Yasuhiro Yamada, Kiyohiro Imai:
- Journal Title
  
  Hemoglobin 29・1
  
  Pages: 1-10
- Data Source
  KAKENHI-PROJECT-17590501
[Journal Article] Rapid disease progression correlates with instability of mutant SOD1 in familial ALS.2005
- Author(s)
  T Sato, T Nakanishi, Y Yamamoto, PM Andersen, Y Ogawa, K Fukada, Z Zhou, F Aoike, F Sugai, S Nagano, S Hirata, M Ogawa, R Nakano, T Ohi, T Kato, M Nakagawa, T Hamasaki, A Shimizu, S Sakoda
- Journal Title
  
  Neurology 65・12
  
  Pages: 1954-1957
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590466
[Journal Article] Hb KOCHI [β141(H19)Leu→Val (g.1404 C→G); 144-146(HC1-3)Lys-Tyr-His→O (g.1413 A→T)] : A NEW VARIANT WITH INCREASED OXYGEN AFFINITY.2005
- Author(s)
  A Miyazaki, T Nakanishi, A Shimizu, M Mizobuchi, Y Yamada, K Imai
- Journal Title
  
  Hemoglobin 29・1
  
  Pages: 1-10
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590466
[Journal Article] Rapid disease progression correlates with instability of mutant SOD1 in familial ALS.2005
- Author(s)
  T Sato, T Nakanishi, Y Yamamoto, PM Andersen, Y Ogawa, K Fukada, Z Zhou, F Aoike, F Sugai, S Nagano, S Hirata, M Ogawa, R Nakano, T Ohi, T Kato, M Nakagawa, T Hamasaki, A Shimizu, S Sakoda
- Journal Title
  
  Neurology 65(12)
  
  Pages: 1954-1957
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590466
[Journal Article] Proteomics-based discovery of α-enolase autoantibody in sera of lung adenocarcinoma2005
- Author(s)
  Nakanishi T, Takeuchi T, et al.
- Journal Title
  
  Proceedings of 53th ASMS conference on mass spectrometry and allied topics 248(MP30)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590502
[Journal Article] New approaches towards laboratory diagnosis of isolated sulfite oxidase deficiency2004
- Author(s)
  J.O.Sass, T Nakanishi, T Sato, A Shimizu
- Journal Title
  
  Annals of Clinical Biochemistry 41
  
  Pages: 157-159
- Data Source
  KAKENHI-PROJECT-16590466
[Journal Article] Identification of two novel mutations in the Cu/Zn superoxide dismutase gene with familianl amyotrophic lateral sclerosis : mass spectrometric and genomic analyses.2004
- Author(s)
  Sato T, Yamamoto Y, Nakanishi T, Fukada K, Sugai F, Zhou Z, Okuno T, Nagano S, Hirata S, Shimizu A, Sakoda S
- Journal Title
  
  J Neurol Sei 218(1-2)
  
  Pages: 79-83
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590466
[Journal Article] Identification of two novel mutations in the Cu/Zn superoxide dismutase gene with familial amyotrophic lateral sclerosis : mass spectrometric and genomic analyses.2004
- Author(s)
  Sato T, Yamamoto Y, Nakanishi T, Fukada K, Sugai F, Zhou Z, Okuno T, Nagano S, Hirata S, Shimizu A, Sakoda S
- Journal Title
  
  J Neurol Sci 218(1-2)
  
  Pages: 79-83
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590466
[Journal Article] Effect of mutated transporters associated with antigen-processing 2 on characteristic major histocompatibility complex binding peptides : analysis using electrospray ionization tandem mass spectrometry.2004
- Author(s)
  G.Kageyama, S.Kawano, S.Kanagawa, S.Kondo, M.Sugita, T.Nakanishi, A.Shimizu, S.Kumagai
- Journal Title
  
  Rapid Communications in Mass Spectrometry 18
  
  Pages: 995-1000
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590466
[Journal Article] Development of an isotope-dilution mass spectrometric assay for HbA1c based on enzyme-cleaved peptide analysis.2004
- Author(s)
  K Iguchi, T Nakanishi, A Miyazaki, A Shimizu, A Ota
- Journal Title
  
  Journal of Chromatography B 806
  
  Pages: 25-31
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590466
[Journal Article] Modification of cysteine residue in transthyretin and a synthetic peptide, analyses by electrospray ionization mass spectrometry.2004
- Author(s)
  T Nakanishi, T Sato, S Sakoda, M Yoshioka, A Shimizu
- Journal Title
  
  Biochimica et Biophysica Acta 1698
  
  Pages: 45-53
- Data Source
  KAKENHI-PROJECT-16590466
[Journal Article] Detection and characterization of variant and modified structures of proteins in blood and tissues by mass spectrometry
- Author(s)
  Akira Shimizu, Toyofumi Nakanishi, Ayako Miyazaki
- Journal Title
  
  Mass Spectrometry Review (in press)
- Data Source
  KAKENHI-PROJECT-17590501
[Journal Article] Detection and characterization of variant and modified structures of proteins in blood and tissues by mass spectrometry.
- Author(s)
  Akira Shimizu, Toyofumi Nakanishi, Ayako Miyazaki
- Journal Title
  
  Mass Spectrometry Reviews (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590466
[Journal Article] Detection and characterization of variant and modified structures of proteins in blood and tissues by mass spectrometry.
- Author(s)
  Akira Shimizu, Toyofumi Nakanishi, Ayako Miyazaki
- Journal Title
  
  Mass Spectrometry Reviews (in press)
- Data Source
  KAKENHI-PROJECT-16590466
[Journal Article] Serum Protein Profile of Rheumatoid Arthritis Treated with Anti-TNF therapy (Infliximab).
- Author(s)
  Takeuchi T, Nakanishi T, et al.
- Journal Title
  
  J Chromatogr B (In press)
- NAID
  10025806140
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590502
[Journal Article] Detection and characterization of variant and modified structures of proteins in blood and tissues by mass spectrometry.
- Author(s)
  Akira Shimizu, Toyofumi Nakanishi, Ayako Miyazaki
- Journal Title
  
  Mass Spectrometry Reviews (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590466
[Journal Article] Serum Protein Profile of Rheumatoid Arthritis Treated with Anti-TNF therapy (Infliximab).
- Author(s)
  Takeuchi T, Nakanishi N, Tabushi Y, Hata A, Shoda T, Kotani T, Shimizu A, Takubo T, Makino S, Hanafusa T.
- Journal Title
  
  J Chromatogr B (in press)
- NAID
  10025806140
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590502
[Patent] 毛髪中に含まれる生理活性物質の解析方法2012
- Inventor(s)
  中西豊文
- Industrial Property Rights Holder
  大阪医科大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2012-198042
- Filing Date
  2012-09-10
- Data Source
  KAKENHI-PROJECT-22590540
[Patent] 扁平上皮癌の診断用キット及び判定方法2007
- Inventor(s)
  藤田能久、中西豊文、馬渕秀明、清水章
- Industrial Property Rights Holder
  財団法人大阪産業振興機構
- Industrial Property Number
  2007-118582
- Filing Date
  2007-04-27
- Data Source
  KAKENHI-PROJECT-19590574
[Presentation] MALDI-TOFMS法による尿中単クローン性免疫グロブリンκ／λ鎖の迅速検出法の確立2020
- Author(s)
  麻野秀一、中西豊文、五十嵐一雄
- Organizer
  第４５回日本医用マススペクトル学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07928
[Presentation] MALDI-TOFMS法による尿中単クローン性免疫グロブリン軽鎖のスクリーニング法の確立2020
- Author(s)
  麻野秀一、中西豊文
- Organizer
  第６７回日本臨床検査医学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07928
[Presentation] 質量イメージング法を用いたハロペリドール由来ピリジニウム代謝物の脳内分布に関する可視化の検討2015
- Author(s)
  吉田原規、中西豊、杉本香奈、巽信二、五十嵐一雄
- Organizer
  第４０回日本医用マススペクトル学会年会
- Place of Presentation
  浜松市
- Year and Date
  2015-09-17
- Data Source
  KAKENHI-PROJECT-25513010
[Presentation] 新鮮凍結乳癌組織切片を用いたMALDI-IMS解析による乳癌特異タンパク分子候補の同定2015
- Author(s)
  佐藤七夕子、中西豊文、岩本充彦、内山和久
- Organizer
  第４０回日本医用マススペクトル学会年会
- Place of Presentation
  浜松市
- Year and Date
  2015-09-17
- Data Source
  KAKENHI-PROJECT-25513010
[Presentation] Brain distribution studies of anti-psychotic drug in mouse with MALDI-TOF MS imaging : Haloperidol2015
- Author(s)
  Igarashi K, Yoshida M, Nakanishi T
- Organizer
  TIAFT2015（国際法中毒学会2015）
- Place of Presentation
  Florence
- Year and Date
  2015-08-29
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25513010
[Presentation] 質量分析イメージングによる毛髪中薬物の分析2014
- Author(s)
  三木昭宏, 鎌田徹, 志摩典明, 片木宗弘, 中西豊文, 土橋均
- Organizer
  日本法中毒学会第33年会　シンポジウム
- Place of Presentation
  名古屋
- Year and Date
  2014-07-04
- Invited
- Data Source
  KAKENHI-PROJECT-24590065
[Presentation] Hair analysis for drugs by mass spectrometry imaging: A new perspective to investigate drug use history.2013
- Author(s)
  Miki A, Kamata T, Shima N, Katagi M, Tatsuno M, Zaitsu K, Nakanishi T, Sato T, Tsuchihashi H, Suzuki K
- Organizer
  50th Annual Meeting of the International Association of Forensic Toxicologists
- Place of Presentation
  Hamamatsu
- Data Source
  KAKENHI-PROJECT-25513010
[Presentation] MALDI-TOF MS法による多菌種混在試料中の迅速同定に関する基礎的検討（第2報2013
- Author(s)
  中西豊文、東山智宣、松山由美子、田窪孝行
- Organizer
  第38回　日本医用マススペクトル学会
- Place of Presentation
  神戸市
- Data Source
  KAKENHI-PROJECT-25513010
[Presentation] 質量分析を利用した酸化生成物の解析2013
- Author(s)
  七里元督、石田規子、萩原義久、吉田康一、中西豊文
- Organizer
  第３８回日本医用マススペクトル学会年会
- Place of Presentation
  神戸市産業振興センター　ハーバーホール、神戸市
- Data Source
  KAKENHI-PROJECT-24659186
[Presentation] 質量イメージング法による病理組織診断の可能性と将来像2013
- Author(s)
  中西豊文
- Organizer
  第60回日本臨床検査医学会学術集会
- Place of Presentation
  神戸市
- Data Source
  KAKENHI-PROJECT-25513010
[Presentation] 質量分析を利用した酸化生成物の解析2013
- Author(s)
  七里元督、石田規子、萩原義久、吉田康一、中西豊文
- Organizer
  第38回　日本医用マススペクトル学会
- Place of Presentation
  神戸市
- Data Source
  KAKENHI-PROJECT-25513010
[Presentation] On-tissue消化／質量イメージング法による病理組織診断の現状とその将来像2013
- Author(s)
  中西豊文
- Organizer
  第40回BMSコンファレンス
- Place of Presentation
  宮崎市
- Invited
- Data Source
  KAKENHI-PROJECT-25513010
[Presentation] 組織／毛髪切片の質量イメージング解析―可能性とその限界―～生命・地球・宇宙・材料科学における新展開～2013
- Author(s)
  中西豊文
- Organizer
  イメージング質量分析シンポジウム
- Place of Presentation
  千葉市
- Invited
- Data Source
  KAKENHI-PROJECT-25513010
[Presentation] MALDI-イメージングによる臨床分析と疾患診断への応用2012
- Author(s)
  上田一仁、中西豊文、田窪孝行
- Organizer
  第５２回日本臨床化学会年会
- Place of Presentation
  いわて県民情報交流センター（盛岡市）
- Invited
- Data Source
  KAKENHI-PROJECT-22590540
[Presentation] Imaging hair analysis for drugs: A new perspective to investigate drug use history.2012
- Author(s)
  Kamata T, Shima N, Miki A, Zaitsu K, Katagi M, Tatsuno M, Nakanishi T, Sato T, Tsuchihashi H, Suzuki K.
- Organizer
  19th Mass Spectrometry Conference(IMSC2012)
- Place of Presentation
  Kyoto)
- Data Source
  KAKENHI-PROJECT-22590540
[Presentation] 新規がん診断マーカーの探索~質量分析技術の臨床応用2012
- Author(s)
  中西豊文
- Organizer
  第65回日本臨床化学会近畿支部例会
- Place of Presentation
  大阪
- Year and Date
  2012-10-20
- Data Source
  KAKENHI-PROJECT-22590540
[Presentation] MALDI- イメージングによる臨床分析と疾患診断への応用2012
- Author(s)
  上田一仁、中西豊文、田窪孝行
- Organizer
  第52回日本臨床化学会年会
- Place of Presentation
  盛岡
- Data Source
  KAKENHI-PROJECT-22590540
[Presentation] Identification of amyloidogenic proteins inFFPE tissue sections by MALD- imaging coupled with on-tissue digestion and immunohistochemical /microscopic examinations. 19th Mass2012
- Author(s)
  Nakanishi T, Ito M, Nirasawa T, UenoT, Tsuji M, Takubo T.
- Organizer
  Spectrometry Conference (IMSC2012)
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-22590540
[Presentation] Identification of amyloidogenic proteins in FFPE tissue sections by MALD-imaging coupled with on-tissue digestion and Immunohistochemical/microscopic examinations.2012
- Author(s)
  Nakanishi T, Ito M, Nirasawa T, Ueno T, Tsuji M, Takubo T.
- Organizer
  19th Mass Spectrometry Conference (IMSC2012)
- Place of Presentation
  京都国際会館（京都市）
- Data Source
  KAKENHI-PROJECT-22590540
[Presentation] MSイメージングによるアミロイド症診断および薬物動態追跡の試み2012
- Author(s)
  中西豊文
- Organizer
  第３７回日本医用マススペクトル学会年会
- Place of Presentation
  愛知県産業労働センター（名古屋市）
- Invited
- Data Source
  KAKENHI-PROJECT-22590540
[Presentation] MS イメージングによるアミロイド症診断および薬物動態追跡の試み2012
- Author(s)
  中西豊文
- Organizer
  第37回日本医用マススペクトル学会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-22590540
[Presentation] The detection of disease-specific proteins in clinical samples by the soft-ionization mass spectrometry.2011
- Author(s)
  Nakanishi T
- Organizer
  IUPAC internationalCongree on Analytical Sciences
- Place of Presentation
  Kyo
- Data Source
  KAKENHI-PROJECT-22590540
[Presentation] The detection of disease-specific proteins in clinical samples by the soft-ionization mass spectrometry2011
- Author(s)
  Nakanishi, T
- Organizer
  IUPAC international Congress on Analytical Sciences 2011
- Place of Presentation
  国立京都国際会館
- Data Source
  KAKENHI-PROJECT-21590642
[Presentation] The detection of disease-specific proteins in clinical samples by the soft-ionization mass spectrometry2011
- Author(s)
  Nakanishi, T
- Organizer
  IUPAC international Congress on Analytical Sciences 2011
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-21590642
[Presentation] MALDI-イメージングによる臨床組織切片を用いた病理診断の基礎的検討2011
- Author(s)
  上田一仁、中西豊文、韮澤崇、伊藤美奈子、田窪孝行
- Organizer
  第36回日本医用マススペクトル学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22590540
[Presentation] MALDI-イメージングによる臨床組織切片を用いた病理診断の基礎的検討2011
- Author(s)
  上田一仁、中西豊文、韮澤崇、伊藤美奈子、田窪孝行
- Organizer
  第36回日本医用マススペクトル学会
- Place of Presentation
  ホテル阪急エキスポパーク(大阪)
- Year and Date
  2011-09-15
- Data Source
  KAKENHI-PROJECT-22590540
[Presentation] The detections of disease-specific proteins in clinical samples by the soft-ionization mass spectrometry2011
- Author(s)
  T.Nakanishi
- Organizer
  IUPAC International Congress on Analytical Sciences 2012
- Place of Presentation
  京都国際会議場(京都)
- Year and Date
  2011-05-23
- Data Source
  KAKENHI-PROJECT-22590540
[Presentation] Detetction of alpha-enolase and triosephosphate isomerase in sera from patients with pancreatic cancer by autoantibodiomics analysis.2010
- Author(s)
  Nakanishi T, Takaori K, C.Iacobuzio-Donahue A, Yachida S, Hruban RH, Miyamoto Y, Tanigawa N, Y.Y.Tabushi Y, Takubo T.
- Organizer
  58^<th> ASMS Conference on Mass Spectrometry
- Place of Presentation
  Salt Lake, CO, USA
- Data Source
  KAKENHI-PROJECT-21590642
[Presentation] Detetction of alpha-enolase and triosephosphate isomerase in sera from patients with pancreatic cancer by autoantibodiomics analysis2010
- Author(s)
  Nakanishi T, Takaori K, C. Iacobuzio-Donahue A, Yachida S, Hruban RH, Miyamoto Y, Tanigawa N, Tabushi Y, Takubo T.
- Organizer
  58^<th> ASMS Conference on Mass Spectrometry
- Place of Presentation
  Salt Lake, CO, USA
- Data Source
  KAKENHI-PROJECT-21590642
[Presentation] Detetction of alpha-enolase and trio sephosphate isomerase in sera from pati ents with pancreatic cancer by autoanti bodiomics analysis.2010
- Author(s)
  Nakanishi T, Takaori K, C. Iacobuzio-Donahue A, Yachida S, Hruban RH, Miy amoto Y, Tanigawa N, Tabushi Y, TakuboT.
- Organizer
  58th ASMS Confere nce on Mass Spectrometry.
- Place of Presentation
  Salt LakeCO, USA
- Data Source
  KAKENHI-PROJECT-22590540
[Presentation] アルツハイマー病患者脳前頭葉組織切片内アミロイドβペプチドとミエリン塩基性タンパクのトポロジー2010
- Author(s)
  中西豊文、韮澤崇、吉岡正則、Richard M.Caprioli
- Organizer
  第58回質量分析総合討論会/第1回アジア・オセアニア質量分析会議
- Place of Presentation
  つくば国際会議場(つくば市)
- Year and Date
  2010-06-17
- Data Source
  KAKENHI-PROJECT-22590540
[Presentation] Causative cysteine-S-sulfonate is a good reagent to elucidate a myloid precipitation by mass spectrometry for image analysis2009
- Author(s)
  M.Yoshioka, K.Moriuchi, T.Nakanishi
- Organizer
  6^<th> International forum on chemistry of functional organic chemicals(IFOC-6)
- Place of Presentation
  学士院会館(東京)
- Data Source
  KAKENHI-PROJECT-20659093
[Presentation] イメージングマススペクトロメトリー2009
- Author(s)
  中西豊文, RM.Caprioli
- Organizer
  第34回日本医用マススペクトル学会
- Place of Presentation
  近畿大学(大阪市)
- Year and Date
  2009-11-21
- Data Source
  KAKENHI-PROJECT-20659093
[Presentation] MALDI-イメージングによる組織切片内発現タンパク質の空間的・質的・量的解析2009
- Author(s)
  中西豊文
- Organizer
  第70回北陸質量分析談話会(日本医用マス学会北陸支部会)
- Place of Presentation
  福井大学医学部(福井市)
- Year and Date
  2009-11-21
- Data Source
  KAKENHI-PROJECT-20659093
[Presentation] 質量イメージング/切片上断片化法を用いた組織切片中のタンパク質解析2009
- Author(s)
  中西豊文, RM Caprioli
- Organizer
  第57回質量分析総合討論会
- Place of Presentation
  大阪国際交流センター(大阪市)
- Data Source
  KAKENHI-PROJECT-20659093
[Presentation] トランスサイレチンのシスティン-S-スルホン酸によるアミロイド沈澱の化学的解析2009
- Author(s)
  吉岡正則, 森内一嘉, 中西豊文, 山本大助, 辻求, 田窪孝行
- Organizer
  第19回日本臨床化学会近畿支部総会
- Place of Presentation
  高槻市
- Year and Date
  2009-01-24
- Data Source
  KAKENHI-PROJECT-20659093
[Presentation] 質量イメージング/切片上断片化法を用いた組織切片中のタンパク質解析の現状と問題点2009
- Author(s)
  中西豊文, RM.Caprioli
- Organizer
  日本ヒトプロテオーム機構(JHUPO)第7回大会
- Place of Presentation
  北里大学(東京)
- Data Source
  KAKENHI-PROJECT-20659093
[Presentation] 自己抗体を標的にした癌マーカー候補の検索2007
- Author(s)
  中西豊文
- Organizer
  第58回日本電気泳動学会総会
- Place of Presentation
  宇部市
- Data Source
  KAKENHI-PROJECT-19590574
[Presentation] ダウン症モデルTs65Dnマウスへの長期ビタミンE投与の行動へ及ぼす効果
- Author(s)
  七里元督、中西豊文、吉田康一、玉井浩
- Organizer
  日本ビタミン学会第67回大会
- Place of Presentation
  奈良県奈良市新公会堂
- Year and Date
  2015-06-05 – 2015-06-06
- Data Source
  KAKENHI-PROJECT-24659186
[Presentation] MALDI-TOF MSによる非結核性抗酸菌臨床分離株同定法の前処理法最適化の実際
- Author(s)
  東山智宣、中西豊文
- Organizer
  日本医用マススペクトル学会年会
- Place of Presentation
  三井ガーデンホテル千葉
- Year and Date
  2014-10-16 – 2014-10-17
- Data Source
  KAKENHI-PROJECT-25513010
[Presentation] 毛髪縦断面MALDI-MS-SRMイメージングによる薬物／嗜好品の定量的動態解析
- Author(s)
  中西豊文
- Organizer
  日本法中毒学会第３３回年会
- Place of Presentation
  名古屋大学シンポジオンホール
- Year and Date
  2014-07-04 – 2014-07-14
- Data Source
  KAKENHI-PROJECT-25513010

1. SHIMIZU Akira (00028581)

# of Collaborated Projects: 13 results

# of Collaborated Products: 25 results
2. TAKEUCHI Toru (10330078)

# of Collaborated Projects: 7 results

# of Collaborated Products: 9 results
3. TAKUBO Takayuki (60163359)

# of Collaborated Projects: 6 results

# of Collaborated Products: 39 results
4. KISHIKAWA Masahiko (40268199)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
5. TABUSHI Yoko (80388256)

# of Collaborated Projects: 4 results

# of Collaborated Products: 6 results
6. NAKAGAWA Toshimasa (30237226)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
7. TAKAORI Kyoichi (10329485)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
8. MIYAZAKI Ayako (20298772)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
9. MIYAMOTO Yoshiharu (20368096)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
10. MAKINO Shigeki (20268204)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. TSUJI Motomu (60144466)

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
12. MISHIBA Yuko (80377415)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. IMAGAWA Akihisa (80373108)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. TERASAKI Jungo (90351395)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. HANAFUSA Toshiaki (60164886)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. YAMAMOTO Daisuke (50240106)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
17. NAITO Yasuhide (40237186)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. TSUCHIHASHI Hitoshi (40596029)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
19. SATO Takako (10530420)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
20. KOTANI Takuya (80411362)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. MOTOTADA Shichiri (20434780)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
22. HATANAKA Michiyo (50218484)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. IKEDA Tsunehiko (70222891)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. MURAO Hitoshi (00278540)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
25. GOTO Isao (90330084)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 岩本充彦 (20351398)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 増井俊彦 (20452352)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 五十嵐一雄 (80098467)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
29. MIKI Akihiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
30. KAMATA Tooru

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
31. SHIMA Noriaki

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
32. ZAITSU Kei

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
33. KATAGI Munehiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
34. YAGI Masayuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. SUZUKI Youichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

NAKANISHI Toyofumi 中西 豊文

NAKANISHI TOYOFUMI 中西 豊文

Research Projects

Research Products

Co-Researchers

Identifications of pancreatic cancer specific neo-antigens with the autoantibodiomics and verifications of diagnostic utilities of its autoantibody screening to neo-antigensPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

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Identifications of abnormal modified proteins localized in amyloid tissues by MALDI-imaging and clarification of formation of amyloid fibrilPrincipal Investigator

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Investigation of the molecular mechanism of the radical reaction to induce the amyloid fibril derived from the transthyretinPrincipal Investigator

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Identifications of non-Hodgkin's lymphoma (NHL)-specific antigens bounded with autoantibodies in plasma derived from patients with NHL by an autoantibodiomicsPrincipal Investigator

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Identifications of diagnostic biomarkers specific binding to soluble proteins of adenocarcinoma A 549 cell lines by an autoantibodiomicsPrincipal Investigator

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NAKANISHI Toyofumi 中西豊文

NAKANISHI TOYOFUMI 中西豊文