KUROSAKI Masayuki 黒崎雅之

Researcher Number	10280976
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2007 – 2010: University of Yamanashi, Deparment of Research Interdisciplinary, Graduate School of Medicine and Engineering, Research Fellow 2006: 山梨大学, 大学院医学工学総合研究部, 医学研究員 2003: 医科歯科大, 医学部附属病院, 助手 2002: Tokyo Medical and Dental Uniersity, Department of Gastroenterology and Hepatology, Instructor, 医学部附属病院, 助手 2000 – 2001: 東京医科歯科大学, 医学部・附属病院, 助手 1999: 東京医科歯科大学, 医学部, 教授 1996 – 1999: 東京医科歯科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Gastroenterology / Gastroenterology Except Principal Investigator Gastroenterology / Gastroenterology / Biological Sciences
Keywords	Principal Investigator C型肝炎ウイルス / NS5A / インターフェロン / apoptosis / HCV / NS5A蛋白 / mutation / Polymerase gene / Henatitis B virus / polymerase遺伝子 … More / domain A / domain B / Polymerase遺伝子 / breakthrough hepatitis / Lamivudine / 潜在的変異 / 耐性変異 / HBV / chronic hepatitis / signal transduction / TNF alpha / Interferon / C型肝ウイルス / C型慢性肝炎 / データマイニング / 個別化診療 / 肝がん / C型肝炎 / データ・マイニング / NSSA / シグナル伝達 / C型肝炎ウィルス / differential display / 発癌 … More Except Principal Investigator インターフェロン / C型肝炎ウイルス / 慢性肝炎 / replicon / interferon / Interferon / subtraction / NS5A / HCV / chronic hepatitis / Hepatitis C virus / 自然免疫 / C型肝炎 / innate immunity / IRF-1 / apoptosis / 肝癌 / 肝細胞癌 / NS5A protein / NS5A蛋白 / Chronic hepatitis / C型慢性肝炎 / リバビリン / レプリコン / 抗ウイルス療法 / 分子標的治療 / レプリコン・システム / 遺伝子発現 / 消化器疾患 / ribavirin / Chronic henatic C / 予測発癌率 / 予測著効率 / インターフェロン療法 / データ・マイニング / Hepatitis C Virus / NF-KB / microarray / NS5A領域 / interferon regulatory factor 3 / interferon sensitivity determining region / interferon regulatory factor 1 / primary biliary cirrhosis / autoimmune hepatitis / hepatoma / 原発性胆汁性肝硬変 / 自己免疫性肝炎 / signal transduction / TNF alpha / ISDR / リン酸化 / decorin / oncogene / hepatocellular carcinoma / CD81 / Decorin / 癌遺伝子 / hepatitis C virus / hepatitis C / 転写活性 / C型肝炎ウィルス / 薬剤耐性 / RIG-I / テラプレビル / IL28B / IPS-1 / RIG-1 / 肝癌細胞 / 感染レセプター / Small interfering RNA / ウイルスベクター / 酵母 / NS5A遺伝子 Less

Data mining analysis for the investigation of clinical features of chronic hepatitis CPrincipal Investigator
- Principal Investigator
  
  KUROSAKI Masayuki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  University of Yamanashi
Association of gene expression involving innate immunity and genetic variation in IL28B with antiviral response
- Principal Investigator
  
  ASAHINA Yasuhiro
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  University of Yamanashi
Pathogenesis of chronic hepatitis C and hepatocellular carcinoma and predictive factors determined by data mining
- Principal Investigator
  
  ASAHINA Yasuhiro
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  University of Yamanashi
Analysis of the polymerase gene of HBV virusPrincipal Investigator
- Principal Investigator
  
  KUROSAKI Masayuki
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  University of Yamanashi
Repliconを用いたC型肝炎ウイルスNS5A蛋白の抗インターフェロン機構解析Principal Investigator
- Principal Investigator
  
  黒崎雅之
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Medical and Dental University
HCV VectorによるHCV感染過程の制御分子の同定
- Principal Investigator
  
  榎本信幸
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Medical and Dental University
Analysis of anti-interferon mechanism by HCV NS5A protein using HCV replicon system
- Principal Investigator
  
  ENOMOTO Nobuyuki
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  University of Yamanashi
  Tokyo Medical and Dental University
Suppression subtraction法による消化器疾患の分子病態解析
- Principal Investigator
  
  榎本信幸
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical and Dental University
Elucidation of the molecular mechanism of chronic hepatitis through the analysis of intracellular function of NS5A protein of hepatitis C virusPrincipal Investigator
- Principal Investigator
  
  KUROSAKI Masayuki
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Medical and Dental University
Suppressive subtraction法による消化器疾患の分子病態の解明
- Principal Investigator
  
  榎本信幸
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical and Dental University
Development of anti-HCV therapy the regulation of NS5A function
- Principal Investigator
  
  ENOMOTO Nobuyuki
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Medical and Dental Uniersity
Analysis of liver diesease related gene expression using subtraction cloning
- Principal Investigator
  
  ENOMOTO Nobuyuki
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Medical and Dental University
C型肝炎ウイルスNS5A蛋白によるインターフェロンシグナル伝達抑制機構の解析Principal Investigator
- Principal Investigator
  
  黒崎雅之
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Medical and Dental University
Mechanism of hepatocarcinogenesis induced by hepatitis C vius and the development of a method for the detection of hepatoma oncogenes
- Principal Investigator
  
  SATO Chifumi
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Medical and Dental University
Function of HCV NS5A protein and the mechanism of interferon resistance
- Principal Investigator
  
  ENOMOTO Nobuyuki
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Medical and Dental University
C型肝炎ウィルス蛋白とインターフェロンシグナル伝達系の相互作用の解析Principal Investigator
- Principal Investigator
  
  黒崎雅之
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Medical and Dental University
C型肝炎ウイルスのインターフェロン抵抗性の分子生物学的機序の解明
- Principal Investigator
  
  ENOMOTO Nobuyuki
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Medical and Dental University
C型肝炎ウイルスによる発癌機序のの分子生物的解明Principal Investigator
- Principal Investigator
  
  黒崎雅之
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Medical and Dental University
A study on the interferon-resistancy of hepatits C virus
- Principal Investigator
  
  SATO Chifumi
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Medical and Dental University
Development of a simple detection method for interferon-sensitive hepatits C virus
- Principal Investigator
  
  SATO Chifumi
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Medical and Dental University

All 2011 2010 2009 2008 2007 2006 2004

All Journal Article Presentation

[Journal Article] Sequences in the Interferon Sensitivity Determining Region and Core Region of Hepatitis C Virus Impact Pretreatment Prediction of Response to Peg-interferon Plus Ribavirin : Data Mining Analysis.2011
- Author(s)
  Kurosaki M, Sakamoto N, Iwasaki M, Sakamoto M, Suzuki Y, Hiramatsu N, Sugauchi F, Tamori A, Nakagawa M, Izumi N.
- Journal Title
  
  J Med Virol 83(3)
  
  Pages: 445-452
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590768
[Journal Article] Changes in hepatitis C viral load during first 14 days can predict the undetectable time point of serum viral load by pegylated interferon and ribavirin therapy.2011
- Author(s)
  Itakura J, Asahina Y, Tamaki N, Hirayama I, Yasui Y, Tanaka T, Sato M, Ueda K, Kuzuya T, Tsuchiya K, Nakanishi H, Kurosaki M, Gabriel GS, Schneider GJ, Izumi N.
- Journal Title
  
  Hepatol Res 41
  
  Pages: 217-224
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590768
[Journal Article] Sequences in the Interferon Sensitivity Determining Region and Core Region of Hepatitis C Virus Impact Pretreatment Prediction of Response to Peg-interferon Plus Ribavirin : Data Mining Analysis.2011
- Author(s)
  Kurosaki M, et al
- Journal Title
  
  J Med Virol
  
  Volume: 83 Pages: 445-452
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590768
[Journal Article] Pretreatment prediction of response to peginterferon plus ribavirin therapy in genotype 1 chronic hepatitis C usmg data mining analysis.2011
- Author(s)
  Kurosaki M, et al
- Journal Title
  
  J Gastroenterol
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590768
[Journal Article] Pretreatment Prediction of Response to Pegylated-Interferon Plus Ribavirin for Chronic Hepatitis C using Genetic Polymorphism in IL28B and Viral Factors.2011
- Author(s)
  Kurosaki M, et al
- Journal Title
  
  J Hepatol
  
  Volume: 54 Pages: 439-448
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590768
[Journal Article] Association of IL28B polymorphism with response to pegylated-interferon alpha plus ribavirin combination therapy in patients with chronic genotype 2 hepatitis C.2011
- Author(s)
  Sakamoto N, Kurosaki M, et al.
- Journal Title
  
  J Medical Virol 25
  
  Pages: 22038-22038
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590768
[Journal Article] Pretreatment Prediction of Response to Pegylated-Interferon Plus Ribavirin for Chronic Hepatitis C using Genetic Polymorphism in IL28B and Viral Factors.2011
- Author(s)
  Kurosaki M, Tanaka Y., Nishida N., Sakamoto N,, Enomoto, N., Honda, M.、Sugiyama M., Matsuura, K., Sugauchi, K., Asahina Y, Nakagawa, M., Watanabe, M., et al.
- Journal Title
  
  J Hepatol
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590768
[Journal Article] Effect of aging on risk for hepatocellular carcinoma in chronic hepatitis C virus infection.2010
- Author(s)
  Asahina Y, Tsuchiya K, Tamaki N, Hirayama I, Tanaka T, Sato M, Yasui Y, Hosokawa T, Ueda K, Kuzuya T, Nakanishi H, Itakura J, Takahashi Y, Kurosaki M, Enomoto N, Izumi N.
- Journal Title
  
  Hepatology 52
  
  Pages: 518-527
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590768
[Journal Article] A predictive model of response to peginterferon ribavirin in chronic hepatitis C using classification and regression tree analysis.2010
- Author(s)
  Kurosaki M, et al
- Journal Title
  
  Hepatol Res
  
  Volume: 40 Pages: 251-260
- NAID
  10027407678
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590769
[Journal Article] Hepatic steatosis in chronic hepatitis C is a significant risk fact or for developing hepatocellular carcinoma independent of age, sex, obesity, fibrosis stage and response to interferon therapy.2010
- Author(s)
  Kurosaki M, et al
- Journal Title
  
  Hepatol Res
  
  Volume: 40 Pages: 870-877
- NAID
  10026696718
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590769
[Journal Article] A Predictive Model of Response to Peginterferon Ribavirin in Chronic Hepatitis C using Classification and Regression Tree Analysis.2010
- Author(s)
  Kurosaki M., Matsunaga K., Hirayama I., Tanaka T., Sato M., Yasui Y., et al.
- Journal Title
  
  Hepatol Res. 40
  
  Pages: 251-260
- NAID
  10027407678
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590768
[Journal Article] Reproducibility and usability of chronic virus infection model using agent-based simulation; comparing with a mathematical model.2010
- Author(s)
  Itakura J, Kurosaki M, Ttakura Y, Maekawa S, Asahina Y, Izumi N, Enomoto N
- Journal Title
  
  Biosystems 99
  
  Pages: 70-78
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590769
[Journal Article] Predictive Model of Response to Peginterferon Ribavirin in Chronic Hepatitis C using Classification and Regression Tree Analysis2010
- Author(s)
  Kurosaki M, et al.
- Journal Title
  
  Hepatol Res 40
  
  Pages: 251-260
- NAID
  10027407678
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590768
[Journal Article] Predictors of virological response to a combination therapy with pegylated interferon plus ribavirin including virus and host factors.2010
- Author(s)
  Izumi N, Asahina Y, Kurosaki M.
- Journal Title
  
  Hepat Res Treat 703602
  
  Pages: 703602-703602
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590768
[Journal Article] A predictive model of response to peginterferon ribavirin in chronic hepatitis C using classification and regression tree analysis.2010
- Author(s)
  Kurosaki M, Matsunaga K, Hirayama T, Tanaka T, Sato M, Yasui Y, Tamaki N, Hosokawa T, Leda K, Tsuchi ya K, Nakanishi H, Ikeda H, Itakura J, Takahashi Y, Asahina Y Higaki M, Enomoto N, Izumi N
- Journal Title
  
  Hepatol Res 40
  
  Pages: 251-260
- NAID
  10027407678
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590769
[Journal Article] Hepatic steatosis in chronic hepatitis C is a significant risk factor for developing hepatocellular carcinoma independent of age, sex, obesity, fibrosis stage and response to interferon therapy.2010
- Author(s)
  Kurosaki M, Ilosokawa T, Matsunaga K, Iirayama I, Tanaka T, Sato M, Yasui Y, Tamaki N, Ueda K, Tsuchiya K, KuzuyaT, Nakanishi H, Itakura J, Takahashi Y, Asahina Y, Enomoto N, Izumi N
- Journal Title
  
  Hepatol Res 40
  
  Pages: 870-877
- NAID
  10026696718
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590769
[Journal Article] Hepatic steatosis in chronic hepatitis C is a significant risk factor for developing hepatocellular carcinoma independent of age, sex, obesity2010
- Author(s)
  Kurosaki M., Hosokawa, T., Matsunaga, K., Hirayama, I., Tanaka, T., Sato, M., Yasui, Y., Tamaki, N., Ueda, K.,Tsuchiya, K., Kuzuya, T., Nakanishi, H., Itakura, J., Takahashi, Y, Asahina, Y, Enomoto, N, Izumi, N
- Journal Title
  
  fibrosis stage and response to interferon therapy Hepatol Res. 40
  
  Pages: 870-877
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590768
[Journal Article] Predictors of virological response to a combination therapy with pegylated interferon plus ribavirin including virus and host factors.2010
- Author(s)
  Izumi N, Asahina Y, Kurosaki M.
- Journal Title
  
  Hepat Res Treat 2010
  
  Pages: 703602-703602
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590769
[Journal Article] Effect of aging on risk for hepatocellular carcinoma in chronic hepatitis C virus infection.2010
- Author(s)
  Asahina Y, Tsuchiya K, Tamaki N, Hirayama T, Tanaka T, Sato M, Yasui Y, Hosokawa T, Ueda K, Kuzuya T, Nakanishi H, Itakura J, Takahashi Y, Kurosaki M, Enomoto N Izumi N
- Journal Title
  
  Hepatology 52
  
  Pages: 518-527
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590769
[Journal Article] Reproducibility and usability of chronic virus infection model using agent-based simulation; comparing with a mathematical model.2009
- Author(s)
  Itakura J., Kurosaki M, Itakura Y, Maekawa S., Asahina Y, Izumi N, et al.
- Journal Title
  
  Biosystems. 12
  
  Pages: 12-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590768
[Journal Article] The presence of steatosis and elevation of alanine aminotransferase level are associated with fibrosis progression in chronic hepatitis C with non-response to interferon therapy2008
- Author(s)
  KurosakiM, et. al.
- Journal Title
  
  J Hepatology (In press)
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590725
[Journal Article] The presence of steatosis and elevation of ALT levels are associated with fibrosis progression in chronic hepatitis C with non-response to IFN2008
- Author(s)
  Masayuki, Kurosaki, et. al.
- Journal Title
  
  Journal of Hepatology 48
  
  Pages: 736-742
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590724
[Journal Article] The presence of steatosis and elevation of alanine aminotransferase level are associated with fibrosis progression in chronic hepatitis C with non-response to interferon therapy2008
- Author(s)
  Kurosaki, M., Matsunaga, K., Hirayama, I., Tanaka, T., Sato, M., Komatsu, N., Umeda, N., Hosokawa, T., Ueda, K., Tsuchiya, K., Nakanishi, H., Itakura, J., Asahina, Y., Miyake, S., Enomoto, N., Izumi, N
- Journal Title
  
  Journal of Hepatology 48
  
  Pages: 736-736
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590725
[Journal Article] External validation of FIB-4 : diagnostic accuracy is limited in elderly2008
- Author(s)
  Kurosaki M, Izumi N
- Journal Title
  
  populations.Hepatology 47
  
  Pages: 352-353
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590768
[Journal Article] The presence of steatosis and elevation of alanine aminotransferase levels are associated with fibrosis progression in chronic hepatitis C with non-response to interferon therapy.2008
- Author(s)
  Kurosaki M, Matsunaga K, Hirayama I, Tanaka T, Sato M, Komatsu N, Umeda N, Ilosokawa T, Ueda K, Tsuchiya K, Nakanishi it, Itakura J, Asahina Y, Miyake S, Enomoto N Izumi N
- Journal Title
  
  J Hepatol 48
  
  Pages: 736-742
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590769
[Journal Article] Potential relevance of cytoplasmic viral sensors and related regulators involving innate immunity in antiviral response.2008
- Author(s)
  Asahina Y, Izumi N, Hirayama I, Tanaka T, Sato M, Yasui Y, Komatsu N, Umeda N, Hosokawa T, Leda K, Tsuchiya K, Nakanishi H, Itakura J, Kurosaki M, Enomoto N, Tasaka M, Sakamoto N, Miyake S
- Journal Title
  
  Gastroenterology 134
  
  Pages: 1396-1405
- NAID
  40016346606
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590769
[Journal Article] The presence of steatosis and elevation of alanine aminotransferase levels are associated with fibrosis progression chronic hepatitis C with non-response to interferon therapy.2008
- Author(s)
  Kurosaki M, etal.
- Journal Title
  
  Journal of Hepatology 48(5)
  
  Pages: 736-42
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590768
[Journal Article] Miyake S Potential relevance of cytoplasmic viral sensors and related regulators involving innate immunity in antiviral response.2008
- Author(s)
  Asahina Y, Izumi N, Hirayama I, Tanaka T, Sato M, Yasui Y, Komatsu N, Umeda N, Hosokawa T, Ueda K, Tsuchiya K, Nakanishi H, Itakura J, Kurosaki M, Enomoto N, Tasaka M, Sakamoto N,
- Journal Title
  
  Gastroenterology 134
  
  Pages: 1396-1405
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590768
[Journal Article] The presence of steatosis and elevation of ALT levels are associated with fibrosis progression in chronic hepatitis C with non-response to IFN2008
- Author(s)
  黒崎雅之, 他
- Journal Title
  
  Journal of Hepatology 48
  
  Pages: 736-742
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590724
[Journal Article] The presence of steatosis and elevation of alanine aminotransferase levels are associated with fibrosis progression in chronic hepatitis C with non-response to interferon therapy.2008
- Author(s)
  Kurosaki M, Matsunaga K, Hirayama I, Tanaka T, Sato M, Komatsu N, Umeda N, et al.
- Journal Title
  
  J Hepatol 48
  
  Pages: 736-742
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590768
[Journal Article] External validation of FIB-4: diagnostic accuracy is limited in elderly populations2008
- Author(s)
  KurosakiM, et. al.
- Journal Title
  
  Hepatology 47
  
  Pages: 357-358
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590725
[Journal Article] 【NASH起因発癌のエビデンス】NASH発癌の危険因子2008
- Author(s)
  細川貴範, 黒崎雅之
- Journal Title
  
  消化器科 48(1)
  
  Pages: 128-131
- Data Source
  KAKENHI-PROJECT-20590768
[Journal Article] External validation of FIB-4 : diagnostic accuracy is limited in elderly populatins.2008
- Author(s)
  Kurosaki M, etal.
- Journal Title
  
  Hepatology 47(1)
  
  Pages: 352-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590768
[Journal Article] External validation of FIB-4 : diagnostic accuracy is limited in elderly populations2008
- Author(s)
  Kurosaki, M., Izumi, N
- Journal Title
  
  Hepatology 47
  
  Pages: 352-352
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590725
[Journal Article] B型慢性肝炎に対するラミブジン治療における寛解維持効果2006
- Author(s)
  黒崎雅之
- Journal Title
  
  消化器科 42
  
  Pages: 400-406
- Data Source
  KAKENHI-PROJECT-18590725
[Journal Article] C型慢性肝炎インターフェロン治療例からの発癌予測因子のデータ-マイニング解析2006
- Author(s)
  黒崎雅之
- Journal Title
  
  肝臓 47巻
- Data Source
  KAKENHI-PROJECT-18590724
[Journal Article] 抗HBV療法2006
- Author(s)
  黒崎雅之
- Journal Title
  
  消化器の臨床 9
  
  Pages: 289-297
- Data Source
  KAKENHI-PROJECT-18590725
[Journal Article] データーマイニングを用いたC型慢性肝炎に対するウイルス学的治療効果予測の網羅的解析2006
- Author(s)
  黒崎雅之
- Journal Title
  
  肝臓 47巻
- Data Source
  KAKENHI-PROJECT-18590724
[Journal Article] Regulation of hepatitis C virus replication by interferon regulatory factor 1.2004
- Author(s)
  Kanazawa N, Kurosaki M, Sakamoto N, Enomoto N, Itsui Y, Yamashiro T, Tanabe Y, Maekawa S, Nakagawa M, Chen CH, Kakinuma S, Oshima S, Nakamura T, Kato T, Wakita T, Watanabe M.
- Journal Title
  
  J virol. 78
  
  Pages: 9713-9720
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370175
[Journal Article] Synergistic inhibition of intracellular hepatitis C virus replication by combination of ribavirin and interferon-alpha.2004
- Author(s)
  Tanabe Y, Sakamoto N, Enomoto N, Kurosaki M, Ueda E, Maekawa S, Yamashiro T, Nakagawa M, Chen CH, Kanazawa N, Kakinuma S, Watanabe M.
- Journal Title
  
  J Infect Dis. 189
  
  Pages: 1129-1139
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370175
[Journal Article] Regulation of hepatitis C virus replication by interferon regulatory factor 1.2004
- Author(s)
  Kanazawa N, Kurosaki M, Sakamoto N, Enomoto N, et al.
- Journal Title
  
  J Virol. 78・18
  
  Pages: 9713-9720
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370175
[Journal Article] Introduction of NS5A mutations enables subgenomic HCV replicon derived from chimpanzee-infectious HC-J4 isolate to replicate efficiently in Huh-7 cells.2004
- Author(s)
  Maekawa S, Enomoto N, Sakamoto N, Kurosaki M, Ueda E, Kohashi T, Watanabe H, Chen CH, Yamashiro T, Tanabe Y, Kanazawa N, Nakagawa M, Sato C, Watanabe M.
- Journal Title
  
  J Viral Hepat. 11
  
  Pages: 394-403
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370175
[Journal Article] Specific inhibition of hepatitis C virus replication by cyclosporin A.2004
- Author(s)
  Nakagawa M, Sakamoto N, Enomoto N, Tanabe Y, Kanazawa N, Koyama T, Kurosaki M, Maekawa S, Yamashiro T, Chen CH, Itsui Y, Kakinuma S, Watanabe M.
- Journal Title
  
  Biochem Biophys Res Commun. 313
  
  Pages: 42-47
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370175
[Presentation] Prediction of Response to Pegylated-Interferon for Chronic Hepatitis C : Impact of SNPs near the IL28B gene and Mutations in the ISDR of HCV Revealed by Data Mining Analysis.2010
- Author(s)
  Kurosaki M, et al.
- Organizer
  米国肝臓学会
- Place of Presentation
  Boston
- Year and Date
  2010-11-01
- Data Source
  KAKENHI-PROJECT-20590768
[Presentation] Prediction of Response to Pegylated-Interferon for Chronic Hepatitis C : Impact of SNPs near the IL28B gene and Mutations in the ISDR of HCV Revealed by Data Mining Analysis.2010
- Author(s)
  Kurosaki M, et al
- Organizer
  米国肝臓学会
- Place of Presentation
  米国ボストン州
- Year and Date
  2010-10-31
- Data Source
  KAKENHI-PROJECT-20590768
[Presentation] Gene expression involving innate immunity and IL28B variation: its association with antiviral response in chronic hepatitis C.2010
- Author(s)
  Asahina Y, Tanaka K, Suzuki Y, Tamaki N, Hoshioka T, Katoh T, Tanaka T, Yasui Y, Hosokawa T, Leda K, Kuzuya T, Tsuchiya K, Nakanishi II, Itakura J Takahashi Y, Kurosaki M, Izumi N.
- Organizer
  The 61st Annual Meeting of the American Association for the Study of Liver Disease (AASLD The Liver Meeting 2010)
- Place of Presentation
  Boston, USA
- Year and Date
  2010-10-30
- Data Source
  KAKENHI-PROJECT-20590769
[Presentation] Association between gene expression involving innate immunity and genetic variation in IL28B in antiviral treatment response.2010
- Author(s)
  Asahina Y, Suzuki Y, Tamaki N, Kato T, Yasui Y, Hosokawa T, Ueda K, Kuzuya T, Tsuchiya K, Nakanishi H, Itakura J, Takahashi Y, Kurosaki M, Izumi N
- Organizer
  17th International Meeting on Hepatitis C Virus and Related Viruses (HCV 2010)
- Place of Presentation
  Tokyo
- Year and Date
  2010-09-11
- Data Source
  KAKENHI-PROJECT-20590769
[Presentation] コンセンサス・ミーティングC型肝炎治療.ペグインターフェロン・リバビリン併用療法2009
- Author(s)
  朝比奈靖浩, 黒崎雅之, 泉並木
- Organizer
  第45回日本肝臓学会総会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20590769
[Presentation] Impact of Mutations in ISDR and Core Region of HCV on Pretreatment Prediction of Sustained Virological Response to Pegylated-interferon Plus Ribavirin Therapy ; Classification and Regression Tree Analysis2009
- Author(s)
  Kurosaki M, et al.
- Organizer
  第16回国際C型肝炎ウイルスおよび関連ウイルスシンポジュウム
- Place of Presentation
  Nice
- Year and Date
  2009-10-06
- Data Source
  KAKENHI-PROJECT-20590768
[Presentation] Impact of Mutations in ISDR and Core Region of HCV on Pretreatment Prediction of Sustained Virological Response to Pegylated-interferon Plus Ribavirin Therapy : Classification and Regression Tree Analysis2009
- Author(s)
  Kurosaki M, et al
- Organizer
  International Symposium on HCV and related viruses
- Place of Presentation
  Nice, France
- Year and Date
  2009-10-03
- Data Source
  KAKENHI-PROJECT-20590768
[Presentation] Dynamic response of innate immunity induced by telaprevir and PEG-IFN/RBV treatment and its association with virological response and HCV variants.2009
- Author(s)
  Asahina Y, Hirayama I, Tamaki N, Yasui Y, Tanaka T, Sato M, Ueda K, Kuzuya T, Tsuchiya K, Nakanishi H, Itakura J, Kurosaki M, Izumi N
- Organizer
  The 60th Annual Meeting of the American Association for the Study of Liver Disease (AASLD The Liver Meeting 2009)
- Place of Presentation
  Boston, USA
- Year and Date
  2009-10-31
- Data Source
  KAKENHI-PROJECT-20590769
[Presentation] Predictive value of FIB-4 index for hepatocelular carcinoma development in chronic hepatitis2009
- Author(s)
  Kurosaki M, et al.
- Organizer
  C米国肝臓学会
- Place of Presentation
  Boston
- Year and Date
  2009-10-30
- Data Source
  KAKENHI-PROJECT-20590768
[Presentation] Gene expression involving innate immunity and hepatitis C virus mutation in resistance to peginterferon alfa-2b plus ribavirin treatment.2008
- Author(s)
  Asahina Y, Hirayam I, Tanaka T, Sato M, Yasui Y, Tamaki N, Umeda N, Hosokawa T, Ueda K, Ikeda H, Tsuchiya K, Nakanishi H, Itakura, Kurosaki M, Maekawa S, Enomoto M, Izumi N
- Organizer
  The 59th Annual Meeting of the American Association for the Study of Liver Disease (AASLD The Liver Meeting 2008)
- Place of Presentation
  San Francisco, USA
- Year and Date
  2008-10-31
- Data Source
  KAKENHI-PROJECT-20590769
[Presentation] Peginterferon/ribavirin併用療法の治療前効果予測データマイニング解析による予測アルゴリズムの構築と検証2008
- Author(s)
  黒崎雅之
- Organizer
  肝臓学会
- Place of Presentation
  愛媛県民文化会館
- Year and Date
  2008-06-06
- Data Source
  KAKENHI-PROJECT-20590768
[Presentation] 発癌からみたALT基準値内のC型肝炎治療ガイドラインの検証 ALT、血小板は発癌予測因子であり、IFN治療によるALT,AFPの制御は発癌リスクを減少させる2007
- Author(s)
  黒崎雅之、泉並木、他
- Organizer
  第43回日本肝臓学会総会
- Place of Presentation
  東京
- Year and Date
  2007-05-31
- Data Source
  KAKENHI-PROJECT-18590725
[Presentation] データマイニング解析によるpeginterferon/ribavirin併用療法の治療効果予測2007
- Author(s)
  黒崎雅之, 他
- Organizer
  第43回日本肝臓学会総会ワークショップ
- Place of Presentation
  東京都
- Year and Date
  2007-06-01
- Data Source
  KAKENHI-PROJECT-18590724
[Presentation] パネルディスカッション:B型慢性肝炎治療の新展開 B型慢性肝炎に対する核酸アナログ製剤の治療成績2007
- Author(s)
  黒崎雅之、泉並木、三宅祥三
- Organizer
  第11回日本肝臓学会大会
- Place of Presentation
  神戸
- Year and Date
  2007-10-19
- Data Source
  KAKENHI-PROJECT-18590725
[Presentation] データマイニング解析による発癌予測2007
- Author(s)
  黒崎雅之, 他
- Organizer
  第43回日本肝臓学会総会
- Place of Presentation
  東京都
- Year and Date
  2007-05-31
- Data Source
  KAKENHI-PROJECT-18590724
[Presentation] ワークショップ:ウイルス肝炎の新しい治療法データマイニング解析によるpeginteferon/ribavirin併用療法の治療効果予測2007
- Author(s)
  黒崎雅之、泉並木、他
- Organizer
  第43回日本肝臓学会総会
- Place of Presentation
  東京
- Year and Date
  2007-05-31
- Data Source
  KAKENHI-PROJECT-18590725
[Presentation] データマイニング解析による発癌予測 C型慢性肝炎におけるsteatosisは、年齢、肝線維化、interferon治療効果と独立した発癌危険因子であることの証明2007
- Author(s)
  黒崎雅之、泉並木、他
- Organizer
  第43回日本肝臓学会総会
- Place of Presentation
  東京
- Year and Date
  2007-06-01
- Data Source
  KAKENHI-PROJECT-18590725

1. ENOMOTO Nobuyuki (20251530)

# of Collaborated Projects: 16 results

# of Collaborated Products: 17 results
2. IZUMI Namiki (20397300)

# of Collaborated Projects: 4 results

# of Collaborated Products: 26 results
3. WATANABE Mamoru (10175127)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
4. ASAHINA Yasuhiro (00422692)

# of Collaborated Projects: 3 results

# of Collaborated Products: 19 results
5. SATO Chifumi (60154069)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. TANAKA Yujiro (70236644)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 坂本直哉 (10334418)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
8. SAKAMOTO Minoru (60324191)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results

KUROSAKI Masayuki 黒崎 雅之

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Data mining analysis for the investigation of clinical features of chronic hepatitis CPrincipal Investigator

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Analysis of the polymerase gene of HBV virusPrincipal Investigator

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Repliconを用いたC型肝炎ウイルスNS5A蛋白の抗インターフェロン機構解析Principal Investigator

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Elucidation of the molecular mechanism of chronic hepatitis through the analysis of intracellular function of NS5A protein of hepatitis C virusPrincipal Investigator

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C型肝炎ウイルスNS5A蛋白によるインターフェロンシグナル伝達抑制機構の解析Principal Investigator

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KUROSAKI Masayuki 黒崎雅之