Ohkoshi Emika 大越絵実加

… Alternative Names

Researcher Number	10287667
Affiliation (Current)	2019: 青森大学, 薬学部, 准教授
Affiliation (based on the past Project Information) *help	2015 – 2017: 青森大学, 薬学部, 准教授 2014: 明海大学, 歯学部, 助教
Review Section/Research Field	Principal Investigator Pathobiological dentistry/Dental radiology Except Principal Investigator Pathobiological dentistry/Dental radiology / Surgical dentistry
Keywords	Principal Investigator 薬剤耐性 / がん幹細胞 Except Principal Investigator 口腔がん / がん幹細胞 / 低酸素環境 / 頭頸部扁平上皮がん / 薬剤耐性

Clarification of metastasis development mechanism in oral cancer stem cellOngoing
- Principal Investigator
  
  梅村直己
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Asahi University
低酸素環境下における口腔癌のがん幹細胞に対する新規分子標的治療の開発
- Principal Investigator
  
  足立誠
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Asahi University
Mechanism of multidrug resistance caused after the treatment targeting CD44, and the strategy for overcoming the resistance in head and neck squamous cell carcinoma.Principal Investigator
- Principal Investigator
  
  OHKOSHI Emika
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Aomori University
  Meikai University

All 2018 2017 2016 Other

All Journal Article Presentation

[Journal Article] Combined SN-38 and gefitinib treatment promotes CD44 degradation in head and neck squamous cell carcinoma cells.2018
- Author(s)
  Nanbu T, Umemura N, Ohkoshi E, Nanbu K, Sakagami H, Shimada J.
- Journal Title
  
  Oncology reports
  
  Volume: 39(1) Pages: 367-375
- DOI
  10.3892/or.2017.6105
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K11691
[Journal Article] Metastasized murine oral squamous cell carcinoma cells induce intratumoral polymorphonuclear myeloid derived suppressor cells.2017
- Author(s)
  Shigeki Sumi, Naoki Umemura, Eiji Takayama, Emika Ohkoshi, Makoto Adachi, Masako Mizuno-Kamiya, Toshihiro Inagaki, Harumi Kawaki, Shinichiro Sumitomo and Nobuo Kondoh
- Journal Title
  
  Oncology Reports
  
  Volume: 37 Pages: 2897-2904
- DOI
  10.3892/or.2017.5575
- Acknowledgement Compliant / Int'l Joint Research / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26462854, KAKENHI-PROJECT-26463055, KAKENHI-PROJECT-15K11096, KAKENHI-PROJECT-15K11331, KAKENHI-PROJECT-17K11890
[Journal Article] Induced overexpression of CD44 associated with resistance to apoptosis on DNA damage response in human head and neck squamous cell carcinoma cells.2017
- Author(s)
  Emika Ohkoshi and Naoki Umemura
- Journal Title
  
  Int J Oncol
  
  Volume: 50 Pages: 387-395
- DOI
  10.3892/ijo.2016.3821
- Open Access / Acknowledgement Compliant / Int'l Joint Research / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26462854, KAKENHI-PROJECT-26861748
[Journal Article] Hyaluronan induces odontoblastic differentiation of dental pulp stem cells via CD44.2016
- Author(s)
  Naoki Umemura, Emika Ohkoshi, Masamichi Tajima, Hirotaka Kikuchi, Tadashi Katayama and Hiroshi Sakagami
- Journal Title
  
  Stem Cell Res Ther
  
  Volume: 7 Pages: 135-146
- DOI
  10.1186/s13287-016-0399-8
- Open Access / Acknowledgement Compliant / Int'l Joint Research / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26462854, KAKENHI-PROJECT-26462892, KAKENHI-PROJECT-26861748
[Journal Article] Triethylated chromones with substituted naphthalenes as tubulin inhibitors2016
- Author(s)
  Kyoko Nakagawa-Goto, Yukako Taniguchi, Yurie Watanabe, Akifumi Oda, Emika Ohkoshi, Ernest Hamel, Kuo-Hsiung Lee, Masuo Goto
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 24 Pages: 6048-6057
- DOI
  10.1016/j.bmc.2016.09.062
- Acknowledgement Compliant / Int'l Joint Research / Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-15H01064, KAKENHI-PROJECT-26460034, KAKENHI-PROJECT-26462854
[Presentation] 青森県産食品素材に関する研究－干菊の成分研究第3報－2017
- Author(s)
  本木雅大、村上浩一、大越絵実加、梅村直己、齋藤俊昭、上田條二
- Organizer
  日本薬学会137年会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-26462854
[Presentation] 薬学生によるセルフメディケーション発信の有用性－健康意識向上に対する地域医療支援－2017
- Author(s)
  井沼道子、相馬理佐、邉見華菜恵、佐々木智江、澤田陽生、中村祐介、村井収平、村上浩一、本木雅大、竹林優佳、小笠原大樹、大越絵実加、佐藤芳久、三浦裕也、上田條二
- Organizer
  日本薬学会137年会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-26462854
[Presentation] 頭頸部扁平上皮癌におけるシスプラチン耐性株の機能解析2017
- Author(s)
  村上浩一、本木雅大、大越絵実加、梅村直己、上田條二
- Organizer
  日本薬学会137年会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-26462854
[Presentation] Baicalein, a major ingredient of herbal medicines, induced inadequate expression of CD44 that attenuated DNA damage-induced apoptosis in human head and neck squamous cell carcinoma.
- Author(s)
  大越絵実加
- Organizer
  日本薬理学会88年会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2015-03-18 – 2015-03-20
- Data Source
  KAKENHI-PROJECT-26462854
[Presentation] 頭頸部扁平上皮癌におけるberberineのNotch-1のダウンレギュレーション
- Author(s)
  大越絵実加
- Organizer
  第56回歯科基礎医学会学術大会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26462854

1. 梅村直己 (80609107)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
2. 足立誠 (10468192)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
3. TOMOMURA Mineko (30217559)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. SUGIMOTO Masahiro (30458963)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 近藤信夫 (40202072)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. 高山英次 (70533446)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. 伊地知圭 (50510278)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. GOTO Masuo

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. KATAYAMA Katayama

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. TAJIMA Masamichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. ODA Akifumi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 坂上宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 菊池寛高

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 川木晴美

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 神谷真子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ohkoshi Emika 大越 絵実加

OHKOSHI Emika 大越 絵実加

Research Projects

Research Products

Co-Researchers

Clarification of metastasis development mechanism in oral cancer stem cellOngoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

低酸素環境下における口腔癌のがん幹細胞に対する新規分子標的治療の開発

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanism of multidrug resistance caused after the treatment targeting CD44, and the strategy for overcoming the resistance in head and neck squamous cell carcinoma.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Combined SN-38 and gefitinib treatment promotes CD44 degradation in head and neck squamous cell carcinoma cells.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Metastasized murine oral squamous cell carcinoma cells induce intratumoral polymorphonuclear myeloid derived suppressor cells.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Induced overexpression of CD44 associated with resistance to apoptosis on DNA damage response in human head and neck squamous cell carcinoma cells.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Hyaluronan induces odontoblastic differentiation of dental pulp stem cells via CD44.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Triethylated chromones with substituted naphthalenes as tubulin inhibitors2016

Author(s)

Journal Title

DOI

Data Source

[Presentation] 青森県産食品素材に関する研究－干菊の成分研究第3報－2017

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 薬学生によるセルフメディケーション発信の有用性－健康意識向上に対する地域 医療支援－2017

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 頭頸部扁平上皮癌におけるシスプラチン耐性株の機能解析2017

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Baicalein, a major ingredient of herbal medicines, induced inadequate expression of CD44 that attenuated DNA damage-induced apoptosis in human head and neck squamous cell carcinoma.

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 頭頸部扁平上皮癌におけるberberineのNotch-1のダウンレギュレーション

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

Ohkoshi Emika 大越絵実加

OHKOSHI Emika 大越絵実加

[Presentation] 薬学生によるセルフメディケーション発信の有用性－健康意識向上に対する地域医療支援－2017