Tanaka Hiroyuki 田中裕之

… Alternative Names

TANAKA HIROYUKI 田中裕之

TANAKA Hiroyuki 田中裕之

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Researcher Number	10293820
Other IDs
Affiliation (Current)	2025: 滋賀短期大学, その他部局等, 教授
Affiliation (based on the past Project Information) *help	2016: 滋賀医科大学, 医学部, 助教 2010 – 2014: 滋賀医科大学, 医学部, 助教 2007: Shiga Univ of Med Sci, Dept of Bicchem. and Mol Biol, Assistant Professor 2006: 滋賀医科大学, 医学部, 助手 2000 – 2004: 滋賀医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator General medical chemistry / Structural biochemistry Except Principal Investigator Laboratory medicine / General medical chemistry / Science and Engineering / Morphology/Structure
Keywords	Principal Investigator NMDA型グルタミン酸受容体 / D-セリン / スプライスバリアント / D-セリンデヒドラターゼ / アストロサイト / PLP酵素 / Ｄ-セリンデヒドラターゼ / Ｄ-アミノ酸オキシダーゼ / Ｄ-セリン / 酸素の活性化 … More / オキシゲナーゼ / X線結晶解析 / 電荷移動錯体 / 結晶構造 / 反応動力学 / 酸素の定量 / 酸素添加酵素 / ニトロフェノール / 非ヘム鉄 / カテコール2,3-ジオキシゲナーゼ … More Except Principal Investigator catechol / catechol 2,3-dioxygenase / oxygenase / カテコール / 酸素添加酵素 / Id3 / 転写因子 foci / 3C assay / 3D-DNA FISH / 転写因子foci / Immuno-FISH / 3D-FISH / 転写因子ファクトリー / 染色体ルーピング / 染色体高次構造 / 核内構造体 / 転写因子 / E2A / frontal analysis / analytical chemistry / serum albumin / gel filtration / clinical chemistry / binding curve / serum / protein / 機能解析 / 嫌気測定 / 低分子リガンド / フロンタル法 / 分析化学 / 血清アルブミン / ゲルろ過 / 臨床検査 / 結合曲線 / 血清 / タンパク質 / micro HPLC / perfusion system / frontal gel chromatography / enzyme column / oxygen measurement / 酸素電極 / 酵素の安定化 / シリンジポンプ / 還流実験 / ミクロHPLC / フロンタルゲルろ過法 / 潅流 / 酵素カラム / 微量酸素 / 酸素濃度測定 / homoprotocatechuic acid / substituent effect / oxygen activation / non-heme iron / reaction mechanism / 酸素分子 / カテコール2,3-ジオキゲナーゼ / 酵素添加酵素 / ニトロフェノール / 電荷移動錯体 / 2,3-ジヒドロキシビフェニール / 結晶構造 / ホモプロトカテク酸 / 置換基効果 / 酸素活性化 / カテコール2,3-ジオキシゲナーゼ / 非ヘム鉄 / 酵素反応機構 / プラナリア / 生殖様式 / 配偶子形成 / トリプトファン / D体アミノ酸 Less

Purification of the functional transcription factor complex and analyses of the factors that constitute the complex
- Principal Investigator
  
  Agata Yasutoshi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General medical chemistry
- Research Institution
  Shiga University of Medical Science
Evolutionary aspects of D-serine metabolism in vertebral brainPrincipal Investigator
- Principal Investigator
  
  TANAKA Hiroyuki
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Shiga University of Medical Science
Mechanisms underlying switching from asexual to sexual reproduction by D-Tryptophan in the planarian Dugesia ryukryuensis
- Principal Investigator
  
  KOBAYASHI Kazuya
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Morphology/Structure
- Research Institution
  Hirosaki University
  Keio University
Accurate measurement of the interaction of serum proteins with low-molecular weight compounds by micro-scale frontal gel chromatogrphy
- Principal Investigator
  
  ISHIDA Tetsuo
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Shiga University of Medical Science
Development of a method to examine the sensitivity of tissues and bacteria for drugs on the basis of direct and sensitive measurement of the concentration of oxygen
- Principal Investigator
  
  ISHIDA Tetsuo
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Shiga University of Medical Science
Elucidation of the structural and mechanistic basis of pollutants-and signal-transmitter-degrading dioxygenases and their directed evolution
- Principal Investigator
  
  HORIIKE Kihachiro
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  SHIGA UNIVERSITY OF MEDICAL SCIENCE
X線結晶解析に基づくジオキシゲナーゼの構造生化学的解明Principal Investigator
- Principal Investigator
  
  田中裕之
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Structural biochemistry
- Research Institution
  Shiga University of Medical Science

All 2017 2016 2015 2014 2013 2012 2011 2008 2007 Other

All Journal Article Presentation Book

[Book] D-Amino Acids : Physiology, Metabolism, and Application2015
- Author(s)
  Tomokazu Ito, Tohru Yoshimura, Tetsuo Ishida, Hiroyuki Tanaka
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-24590351
[Journal Article] The Effect of D-Aspartate on Spermatogenesis in Mouse Testis.2016
- Author(s)
  Tomita K, Tanaka H, Kageyama S, Nagasawa M, Wada A, Murai R, Kobayashi K, Hanada E, Agata Y, Kawauchi A
- Journal Title
  
  Biol Reprod.
  
  Volume: 30 Issue: 2 Pages: 1-7
- DOI
  10.1095/biolreprod.115.134692
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26670136, KAKENHI-PROJECT-16K15215
[Journal Article] Effect of D-serine on spermatogenesis and extracellular signal-regulated protein kinase (ERK) phosphorylation in the testis of the silkworm, Bombyx mori.2014
- Author(s)
  Suzuki C, Tanigawa M, Tanaka H, Horiike K, Kanekatsu R, Tojo M, Nagata Y.
- Journal Title
  
  J Insect Physiol
  
  Volume: 67 Pages: 97-104
- DOI
  10.1016/j.jinsphys.2014.06.003
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24590351
[Journal Article] Immunohistochemical localization of d-serine dehydratase in chicken tissues.2014
- Author(s)
  Nishimura Y, Tanaka H, Ishida T, Imai S, Matsusue Y, Agata Y, Horiike K.
- Journal Title
  
  Acta Histochem.
  
  Volume: in press Issue: 5 Pages: 244-4
- DOI
  10.1016/j.acthis.2013.12.011
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23118515, KAKENHI-PROJECT-24590351, KAKENHI-PROJECT-25460684
[Journal Article] Planarian D-amino acid oxidase is involved in ovarian development during sexual induction.2014
- Author(s)
  Maezawa T, Tanaka H, Nakagawa H, Ono M, Aoki M, Matsumoto M, Ishida T, Horiike K, Kobayashi K.
- Journal Title
  
  Mech of Development
  
  Volume: 132 Pages: 69-78
- DOI
  10.1016/j.mod.2013.12.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24590351, KAKENHI-PROJECT-25460684, KAKENHI-PROJECT-25650104, KAKENHI-PUBLICLY-26114501, KAKENHI-PROJECT-26440180
[Journal Article] Crystallization and preliminary crystallographic analysis of D-aspartate oxidase from porcine kidney2012
- Author(s)
  Senda M., Yamamoto A., Tanaka H., Ishida T., Horiike K., Senda T.
- Journal Title
  
  Acta Crystallogr. Sec. F Sytuct. Biol. Cryst. Commun.
  
  Volume: 68 Issue: 6 Pages: 644-646
- DOI
  10.1107/s1744309112013243
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590351, KAKENHI-PROJECT-24657079
[Journal Article] D-Serine dehydratase from chicken kidney: a vertebral homologue of the cryptic enzyme from Burkholderia cepacia2008
- Author(s)
  Tanaka H.
- Journal Title
  
  J.Biochem 143
  
  Pages: 49-57
- NAID
  10024907433
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590528
[Journal Article] D-Serine dehydratase from chicken kidney : a vertebral homologue of the cryptic enzyme from Burkholderia cepacia2008
- Author(s)
  Tanaka, H
- Journal Title
  
  J. Biochem 143
  
  Pages: 49-57
- NAID
  10024907433
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590528
[Journal Article] D-Serine dehydratase from chicken kidney: a vertebral homologue of the cryptic enzyme from Burkholderia cepacia2008
- Author(s)
  Tanaka H.
- Journal Title
  
  J. Biochem. 143
  
  Pages: 49-57
- NAID
  10024907433
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590528
[Journal Article] Simultaneous measurement of D-serine dehydratase and Damino acid oxidase activities by the detection of 2-oxo-acid formation with reverse-phase high-performance liquid chromatography2007
- Author(s)
  Tanaka, H
- Journal Title
  
  Anal. Biochem 362
  
  Pages: 83-88
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590528
[Journal Article] Functional and structural characterization of D-aspartate oxidase from porcine kidney : non-Michaelis kinetics due to substrate activation.2007
- Author(s)
  Yamamoto A., Tanaka H., Ishida T., Horiike K.
- Journal Title
  
  J. Biochem. 141
  
  Pages: 363-376
- NAID
  10020100678
- Data Source
  KAKENHI-PROJECT-18590528
[Journal Article] Simultaneous measurement of D-serine dehydratase and D-amino acid oxidase activities by the detection of 2-oxo-acid formation with reverse-phase high-performance liquid chromatography2007
- Author(s)
  Tanaka H.
- Journal Title
  
  Anal. Biochem. 362
  
  Pages: 83-88
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590528
[Journal Article] Simultaneous measurement of D-serine dehydratase and D-amino acid oxidase activities by the detection of 2-oxo-acid formation with reverse-phase high-performance liquid chromatography.2007
- Author(s)
  Tanaka H., Yamamoto A., Ishida T., Horiike K.
- Journal Title
  
  Anal. Biochem. 362
  
  Pages: 83-88
- Data Source
  KAKENHI-PROJECT-18590528
[Presentation] E2A and CBP/p300 regulate chromosome dynamics of the TCRβ locus.2017
- Author(s)
  Agata, Y, Wagatsuma K, Terada K, Tanaka H, Ikawa T, Masuda K, Kawamoto H, Kimura H
- Organizer
  7th International Workshop of Kyoto T Cell Conference
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2017-03-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670136
[Presentation] 転写因子E2AとCBP/p300が形成する核内構造体を足場としたTCRβ遺伝子再構成の制御機構.2016
- Author(s)
  寺田晃士、我妻慶祐、田中裕之、伊川友活、増田喬子、河本　宏、縣　保年
- Organizer
  第26回 Kyoto T Cell Conference
- Place of Presentation
  京都市
- Year and Date
  2016-05-21
- Data Source
  KAKENHI-PROJECT-26670136
[Presentation] E2A 転写因子 foci を足場とした T 細胞受容体遺伝子座の染色体ダイナミクス.2016
- Author(s)
  縣　保年、我妻慶祐、寺田晃士、安齋悠樹、田中裕之、伊川友活、増田喬子、河本　宏、木村　宏
- Organizer
  第10回日本エピジェネティクス研究会年会
- Place of Presentation
  豊中市
- Year and Date
  2016-05-20
- Data Source
  KAKENHI-PROJECT-26670136
[Presentation] E2A転写因子ファクトリーを足場としたTCRβ遺伝子の染色体ダイナミクス2015
- Author(s)
  我妻慶祐、寺田晃士、安齋悠樹、田中裕之、伊川友活、増田喬子、河本　宏、湊　長博、縣　保年
- Organizer
  第25回 Kyoto T Cell Conference
- Place of Presentation
  京都市
- Year and Date
  2015-05-15
- Data Source
  KAKENHI-PROJECT-26670136
[Presentation] Escherichia coli由来ジヒドロピリミジンデヒドロゲナーゼのnFeS2鉄硫黄クラスターに配位するアミノ酸残基の役割2013
- Author(s)
  谷泰史、吉田吉孝、秀瀬涼太、齊藤茂樹、中島洋、渡辺芳人、石田哲夫、田中裕之、堀池喜八郎、栗原達夫、江崎信芳、三原久明
- Organizer
  第８６回日本生化学会大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24590351
[Presentation] ヒト血清アルブミンへのダンシルアミノ酸の結合機構2013
- Author(s)
  石田哲夫、田中裕之、西村嘉洋、阪本健補、堀池喜八郎
- Organizer
  第１３回日本蛋白質科学会年会
- Place of Presentation
  鳥取
- Data Source
  KAKENHI-PROJECT-24590351
[Presentation] Switching from asexual to sexual reproduction in the planarian Dugesia ryukyuensis：The role of D-amino acid oxidase2013
- Author(s)
  前澤孝信、田中裕之、小林一也
- Organizer
  第４６回日本発生生物学会大会
- Place of Presentation
  松江
- Data Source
  KAKENHI-PROJECT-24590351
[Presentation] Switching from asexual to sexual reproduction in the planarian Dugesia ryukyuensis : The role of D-amino acid oxidase2013
- Author(s)
  Maezawa, T., Tanaka, H., Kobayashi, K
- Organizer
  46^<th> Annual Meeting for the Japanese Society of Developmental Biologists
- Place of Presentation
  Matsue, Japan
- Year and Date
  2013-05-31
- Data Source
  KAKENHI-PROJECT-22370026
[Presentation] 安定同位体標識ダブシルクロリドによるアミンの定量的分析2013
- Author(s)
  石田哲夫、田中裕之、西村嘉洋、坂本健補、堀池喜八郎
- Organizer
  第８６回日本生化学会大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24590351
[Presentation] D-amino acid oxidase represses the sexual induction in the planarian Dugesia ryukyuensis2011
- Author(s)
  Maezawa, T., Tanaka, H., Nakagawa, H., Horiike, K., Kobayashi, K
- Organizer
  Planarian Regeneration Research Meeting in Kyoto
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2011-11-22
- Data Source
  KAKENHI-PROJECT-22370026
[Presentation] Functional characterization of D-amino acid oxidase from planarian Dugesia ryukyuensis : Non-Michaelis kinetics due to substarate activation2011
- Author(s)
  H.Tanaka
- Organizer
  Planarian Regeneration Research Meeting in Kyoto
- Place of Presentation
  Kansai Seminar House, Kyoto, Japan
- Year and Date
  2011-11-21
- Data Source
  KAKENHI-PROJECT-22370026
[Presentation] ニワトリ腎臓由来のD-セリンデヒドラターゼの精製と性状解析2007
- Author(s)
  田中裕之
- Organizer
  日本生化学会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2007-12-11
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590528
[Presentation] Purification and characterization of chicken kidney D-serine dehydratase2007
- Author(s)
  Tanaka, H
- Organizer
  80th annual meeting of the Japanese Biochemical Society
- Place of Presentation
  Pacifico Yokohama
- Year and Date
  2007-12-11
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590528
[Presentation] フラビンオキシダーゼの生理的酸素濃度における活性測定と基質阻害の解析
- Author(s)
  石田哲夫、田中裕之、西村喜洋、坂本健補、堀池喜八郎
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24590351
[Presentation] 5-Hydroxytryptophan acts as an ovary-inducing substance in asexual worms of the planarian Dugesia ryukyuensis.
- Author(s)
  Nanna Nagao, Takanobu Maezawa, Hiroyuki Tanaka, Kazuya Kobayashi.
- Organizer
  第48回日本発生生物学会大会
- Place of Presentation
  つくば国際会議場
- Year and Date
  2015-06-02 – 2015-06-05
- Data Source
  KAKENHI-PROJECT-24590351
[Presentation] D-Amino acid oxidase is involved in the ovarian development of asexual planarian worms.
- Author(s)
  Hiroyuki Tanaka, Takanobu Maezawa, Yoshihiro Nishimura, Tetsuo Ihida, Kazuya Kobayashi, Yasutohi Agata
- Organizer
  The 2nd International Conference of D-Amino Acid Research
- Place of Presentation
  Utsunomiya, Tochigi, Japan
- Year and Date
  2014-09-02 – 2014-09-05
- Data Source
  KAKENHI-PROJECT-24590351
[Presentation] 脊椎動物の進化とD-セリン代謝
- Author(s)
  田中裕之、石田哲夫、西村嘉洋、坂本健補、堀池喜八郎
- Organizer
  第８６回日本生化学会大会
- Place of Presentation
  横浜
- Invited
- Data Source
  KAKENHI-PROJECT-24590351
[Presentation] D型アスパラギン酸が精子形成に及ぼす影響の検討
- Author(s)
  富田圭司, 影山進, 村井亮介, 花田英紀, 田中裕之, 縣保年, 河内明宏
- Organizer
  第103回　日本泌尿器科学会総会
- Place of Presentation
  石川県　金沢市
- Year and Date
  2015-04-18 – 2015-04-21
- Data Source
  KAKENHI-PROJECT-24590351
[Presentation] プラナリアD-アミノ酸オキシダーゼのクローニングと性状解析
- Author(s)
  西村喜洋、田中裕之、石田哲夫、前澤孝信、小林一也、堀池喜八郎
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24590351

1. ISHIDA Tetsuo (10176191)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
2. KOBAYASHI Kazuya (50360110)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
3. MATSUMOTO Midori (00211574)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. HORIIKE Kihachiro (80089870)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. KIMURA Takahide (70167378)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. KITA Akiko (70273430)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. Agata Yasutoshi (60263141)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
8. WAGATSUMA KEISUKE (10725071)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
9. ANZAI YUKI

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results

Tanaka Hiroyuki 田中 裕之

TANAKA HIROYUKI 田中 裕之

TANAKA Hiroyuki 田中 裕之

Research Projects

Research Products

Co-Researchers

Purification of the functional transcription factor complex and analyses of the factors that constitute the complex

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Evolutionary aspects of D-serine metabolism in vertebral brainPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanisms underlying switching from asexual to sexual reproduction by D-Tryptophan in the planarian Dugesia ryukryuensis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Accurate measurement of the interaction of serum proteins with low-molecular weight compounds by micro-scale frontal gel chromatogrphy

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of a method to examine the sensitivity of tissues and bacteria for drugs on the basis of direct and sensitive measurement of the concentration of oxygen

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of the structural and mechanistic basis of pollutants-and signal-transmitter-degrading dioxygenases and their directed evolution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

X線結晶解析に基づくジオキシゲナーゼの構造生化学的解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] D-Amino Acids : Physiology, Metabolism, and Application2015

Author(s)

Publisher

Data Source

[Journal Article] The Effect of D-Aspartate on Spermatogenesis in Mouse Testis.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effect of D-serine on spermatogenesis and extracellular signal-regulated protein kinase (ERK) phosphorylation in the testis of the silkworm, Bombyx mori.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Immunohistochemical localization of d-serine dehydratase in chicken tissues.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Planarian D-amino acid oxidase is involved in ovarian development during sexual induction.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Crystallization and preliminary crystallographic analysis of D-aspartate oxidase from porcine kidney2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] D-Serine dehydratase from chicken kidney: a vertebral homologue of the cryptic enzyme from Burkholderia cepacia2008

Author(s)

Journal Title

Tanaka Hiroyuki 田中裕之

TANAKA HIROYUKI 田中裕之

TANAKA Hiroyuki 田中裕之