Itonaga Ichiro 糸永一朗

… Alternative Names

ichiro itonaga 糸永一朗

糸永一朗イトナガイチロウ

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Researcher Number	10295181
Other IDs
Affiliation (Current)	2025: 大分大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2014 – 2021: 大分大学, 医学部, 講師 2005: 大分大学, 医学部, 講師 2004: 大分大学, 医学部, 助手 2001: 大分医大, 医学部, 助手 2000: 大分医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Orthopaedic surgery / Basic Section 56020:Orthopedics-related / Orthopaedic surgery
Keywords	Principal Investigator 破骨細胞 / RNAヘリカーゼA / EWS-Fli1 / RNA helicase A / Ewing肉腫 / 液性因子 / 間葉系幹細胞 / 骨肉腫 / cmyc / エピジェネティクス … More / 染色体転座 / ｃ－ｍｙｃ / 染色体不安定性 / 肉腫 / 骨転移 / 骨破壊 / 摩耗紛 / osteolysis / loosening / 人工関節 Less

Analyis of RNA helicase A function on Ewing's sarcoma-specific fusion genePrincipal Investigator
- Principal Investigator
  
  Itonaga Ichiro
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Oita University
Interaction between human osteosarcoma cells and mesenchymal stem cells via IL-8 signaling in tumor microenvironment.Principal Investigator
- Principal Investigator
  
  Itonaga Ichiro
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Oita University
Epigenetic abnormality induced by aberrant c-Myc expression leads to the chromosomal instability.Principal Investigator
- Principal Investigator
  
  ichiro itonaga
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Oita University
骨転位をきたした乳癌細胞による骨破壊および腫瘍増大機序の解明Principal Investigator
- Principal Investigator
  
  糸永一朗
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Oita University
人工関節周囲に生じる骨溶解の病態解明Principal Investigator
- Principal Investigator
  
  糸永一朗
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  大分医科大学

All 2021 2019 2018 2017 2016 2015 2005 Other

All Journal Article Presentation

[Journal Article] Analysis of the signal cross talk via CCL26 in the tumor microenvironment in osteosarcoma2021
- Author(s)
  Kawano M, Iwasaki T, Itonaga I, Kubota Y, Tanaka K, Tsumura H.
- Journal Title
  
  Sci Rep
  
  Volume: 11 Issue: 1 Pages: 18099-18099
- DOI
  10.1038/s41598-021-97153-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09576, KAKENHI-PROJECT-20K09414, KAKENHI-PROJECT-21K09230
[Journal Article] Surrogacy of intermediate endpoints for overall survival in randomized controlled trials of first-line treatment for advanced soft tissue sarcoma in the pre- and post-pazopanib era: a meta-analytic evaluation.2019
- Author(s)
  Tanaka K, Kawano M, Iwasaki T, Itonaga I, Tsumura H.
- Journal Title
  
  BMC Cancer.
  
  Volume: 19 Issue: 1 Pages: 56-56
- DOI
  10.1186/s12885-019-5268-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10866, KAKENHI-PROJECT-18K09110, KAKENHI-PROJECT-17K10971, KAKENHI-PROJECT-18K16666
[Journal Article] A meta-analysis of randomized controlled trials that compare standard doxorubicin with other first-line chemotherapies for advanced/metastatic soft tissue sarcomas.2019
- Author(s)
  Tanaka K, Kawano M, Iwasaki T, Itonaga I, Tsumura H.
- Journal Title
  
  PLoS One
  
  Volume: 14 Issue: 1 Pages: 1-18
- DOI
  10.1371/journal.pone.0210671
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10866, KAKENHI-PROJECT-18K09110, KAKENHI-PROJECT-17K10971, KAKENHI-PROJECT-18K16666
[Journal Article] Interaction between human osteosarcoma and mesenchymal stem cells via an interleukin-8 signaling loop in the tumor microenvironment.2018
- Author(s)
  Kawano M, Tanaka K, Itonaga I, Iwasaki T, Tsumura H.
- Journal Title
  
  Cell Commun Signal.
  
  Volume: 16(1) Issue: 1 Pages: 13-13
- DOI
  10.1186/s12964-018-0225-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10971, KAKENHI-PROJECT-18K09110, KAKENHI-PROJECT-16K10866
[Journal Article] MicroRNA-181c prevents apoptosis by targeting of FAS receptor in Ewing's sarcoma cells.2018
- Author(s)
  Kawano M, Tanaka K, Itonaga I, Iwasaki T, Tsumura H.
- Journal Title
  
  Cancer Cell Int.
  
  Volume: 18 Issue: 1 Pages: 37-37
- DOI
  10.1186/s12935-018-0536-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10971, KAKENHI-PROJECT-15K10451, KAKENHI-PROJECT-18K09110, KAKENHI-PROJECT-16K10866
[Journal Article] MicroRNA-20b promotes cell proliferation via targeting of TGF-β receptor II and upregulates MYC expression in Ewing's sarcoma cells.2017
- Author(s)
  Kawano M, Tanaka K, Itonaga I, Iwasaki T, Tsumura H.
- Journal Title
  
  Int J Oncol.
  
  Volume: 51(6) Issue: 6 Pages: 1842-1850
- DOI
  10.3892/ijo.2017.4155
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10971, KAKENHI-PROJECT-15K10451, KAKENHI-PROJECT-16K10866
[Journal Article] Dendritic Cells Combined with Immunogenic Cell Death Induced by Doxorubicin Produces Antitumor Effects in Osteosarcoma.2016
- Author(s)
  Kawano M, Tanaka K, Itonaga I, Iwasaki T, Miyazaki M, Ikeda S, Tsumura H.
- Journal Title
  
  Oncology Letters.
  
  Volume: 11 Pages: 2169-2175
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26670668
[Journal Article] MicroRNA-301a promotes cell proliferation via PTEN targeting in Ewing's sarcoma cells.2016
- Author(s)
  Kawano M, Tanaka K, Itonaga I, Iwasaki T, Tsumura H.
- Journal Title
  
  International Jnournal of Oncology.
  
  Volume: Apr;48(4): Issue: 4 Pages: 1531-1540
- DOI
  10.3892/ijo.2016.3379
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26670668, KAKENHI-PROJECT-26861200, KAKENHI-PROJECT-15K10451
[Journal Article] Tumor suppressive microRNA-138 inhibits metastatic potential via the targeting of focal adhesion kinase in Ewing's sarcoma cells.2016
- Author(s)
  Kawano M, Tanaka K, Itonaga I, Iwasaki T, Miyazaki M, Ikeda S, Tsumura H.
- Journal Title
  
  International Jnournal of Oncology.
  
  Volume: Mar;48(3): Issue: 3 Pages: 1135-1144
- DOI
  10.3892/ijo.2016.3317
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26670668, KAKENHI-PROJECT-26861200, KAKENHI-PROJECT-15K10451
[Journal Article] Dendrotic cells combined with anti-GITR antibody produce antitumor effects in osteosarcoma.2015
- Author(s)
  Kawano M, Tanaka K, Itonaga I, Iwasaki T, Miyazaki M, Ikeda S, Tsumura H
- Journal Title
  
  Oncol Rep
  
  Volume: 34 Issue: 4 Pages: 1995-2001
- DOI
  10.3892/or.2015.4161
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10451, KAKENHI-PROJECT-26670668, KAKENHI-PROJECT-26861200
[Journal Article] Tumor-suppressive microRNA-let-7a inhibits cell proliferation via targeting of E2F2 in osteosarcoma cells.2015
- Author(s)
  Iwasaki T, Tanaka K, Kawano M, Itonaga I, Tsumura H
- Journal Title
  
  Int J Oncol
  
  Volume: 46 Issue: 4 Pages: 1543-1550
- DOI
  10.3892/ijo.2015.2867
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24592250, KAKENHI-PROJECT-26670668, KAKENHI-PROJECT-26861200
[Journal Article] Dendritic Cells Combined with Immunogenic Cell Death Induced by Doxorubicin Exhibits Antitumor Effects for Osteosarcoma2015
- Author(s)
  M. Kawano, K. Tanaka, I. Itonaga, T. Iwasaki, M. Miyazaki, S. Ikeda, H. Tsumura
- Journal Title
  
  Oncology Leteers
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26670668
[Journal Article] microRNA-93 promotes cell proliferation via targeting of PTEN in osteosarcoma cells.2015
- Author(s)
  Kawano M, Tanaka K, Itonaga I, Ikeda S, Iwasaki T, Tsumura H
- Journal Title
  
  J Exp Clin Cancer Res
  
  Volume: 34 Issue: 1 Pages: 76-76
- DOI
  10.1186/s13046-015-0192-z
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K10451, KAKENHI-PROJECT-26670668, KAKENHI-PROJECT-26861200
[Journal Article] c-MYc represses tumor-suppressive microRNAs, let-7a, miR-16 and miR-29b, and induces cyclin D2-mediated cell proliferation in Ewing’s sarcoma cell line.2015
- Author(s)
  Kawano M, Tanaka K, Itonaga I, Iwasaki T, Tsumura H
- Journal Title
  
  Plos One
  
  Volume: 10 Issue: 9 Pages: e0138560-e0138560
- DOI
  10.1371/journal.pone.0138560
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10451, KAKENHI-PROJECT-26670668, KAKENHI-PROJECT-26861200
[Journal Article] Macrophages that have phagocytosed particles are capable of differentiating into functional osteoclasts2005
- Author(s)
  Yosuke Fujikawa, Ichiro Itonaga, Osami Kudo, Takahisa Hirayama
- Journal Title
  
  Modern Rheumatology 15・5
  
  Pages: 346-351
- Data Source
  KAKENHI-PROJECT-16790849
[Journal Article] Infliximab acts directly on human osteoclast precursors and enhances osteoclast formation induced by receptor activator of nuclear factor kB ligand in vitro2005
- Author(s)
  Chikahiro Takita, Yosuke Fujikawa, Ichiro Itonaga, et al.
- Journal Title
  
  Modern Rheumatology 15・2
  
  Pages: 97-103
- Data Source
  KAKENHI-PROJECT-16790849
[Journal Article] Infliximab acts directly on human osteoclast precursors and enhances osteoclast formation induced by RANKL in vitro
- Author(s)
  Takita C., Fujikawa Y., Itonaga I.et al.
- Journal Title
  
  Modern Rheumatology (掲載予定)
- Data Source
  KAKENHI-PROJECT-16790849
[Presentation] microRNA-93 promotes cell proliferation via targeting of PTEN in Osteosarcoma cells.2015
- Author(s)
  M Kawano, K Tanaka, I. Itonaga, T. Iwasaki, H. Tsumura
- Organizer
  Annual research meeting of the Japanese orthopedic association
- Place of Presentation
  富山国際会議場（富山県、富山市）
- Year and Date
  2015-10-22
- Data Source
  KAKENHI-PROJECT-26670668
[Presentation] microRNA-301a promotes cell proliferation via targeting of PTEN in Ewing’s sarcoma cells2015
- Author(s)
  M Kawano, K Tanaka, I. Itonaga, T. Iwasaki, H. Tsumura.
- Organizer
  Japan Muscular Skeletal Tumor Society Meeting
- Place of Presentation
  かがわ国際会議場（香川県、高松市）
- Year and Date
  2015-07-10
- Data Source
  KAKENHI-PROJECT-26670668
[Presentation] 当科におけるパゾパニブの臨床使用経験
- Author(s)
  糸永一朗
- Organizer
  日本整形外科学会骨・軟部腫瘍学術集会
- Place of Presentation
  大阪国際会議場（大阪府、大阪市）
- Year and Date
  2014-07-17 – 2014-07-18
- Data Source
  KAKENHI-PROJECT-26670668
[Presentation] 関節症状なく足底にリウマトイド結節が生じた1例
- Author(s)
  糸永一朗
- Organizer
  日本リウマチ学会総会
- Place of Presentation
  グランドプリンスホテル新高輪（東京都港区）
- Year and Date
  2014-04-24 – 2014-04-26
- Data Source
  KAKENHI-PROJECT-26670668

1. TANAKA Kazuhiro (10274458)

# of Collaborated Projects: 1 results

# of Collaborated Products: 13 results
2. 池田真一 (70444883)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 河野正典 (30571773)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results

Itonaga Ichiro 糸永 一朗

ichiro itonaga 糸永 一朗

糸永 一朗 イトナガ イチロウ

Research Projects

Research Products

Co-Researchers

Analyis of RNA helicase A function on Ewing's sarcoma-specific fusion genePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Interaction between human osteosarcoma cells and mesenchymal stem cells via IL-8 signaling in tumor microenvironment.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Epigenetic abnormality induced by aberrant c-Myc expression leads to the chromosomal instability.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

骨転位をきたした乳癌細胞による骨破壊および腫瘍増大機序の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

人工関節周囲に生じる骨溶解の病態解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Analysis of the signal cross talk via CCL26 in the tumor microenvironment in osteosarcoma2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Surrogacy of intermediate endpoints for overall survival in randomized controlled trials of first-line treatment for advanced soft tissue sarcoma in the pre- and post-pazopanib era: a meta-analytic evaluation.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A meta-analysis of randomized controlled trials that compare standard doxorubicin with other first-line chemotherapies for advanced/metastatic soft tissue sarcomas.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Interaction between human osteosarcoma and mesenchymal stem cells via an interleukin-8 signaling loop in the tumor microenvironment.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] MicroRNA-181c prevents apoptosis by targeting of FAS receptor in Ewing's sarcoma cells.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] MicroRNA-20b promotes cell proliferation via targeting of TGF-β receptor II and upregulates MYC expression in Ewing's sarcoma cells.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Dendritic Cells Combined with Immunogenic Cell Death Induced by Doxorubicin Produces Antitumor Effects in Osteosarcoma.2016

Author(s)

Journal Title

Data Source

[Journal Article] MicroRNA-301a promotes cell proliferation via PTEN targeting in Ewing's sarcoma cells.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Tumor suppressive microRNA-138 inhibits metastatic potential via the targeting of focal adhesion kinase in Ewing's sarcoma cells.2016

Author(s)

Journal Title

DOI

Data Source

Itonaga Ichiro 糸永一朗

ichiro itonaga 糸永一朗

糸永一朗イトナガイチロウ