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Kawano Masanori  河野 正典

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kawano masanori  河野 正典

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Researcher Number 30571773
Other IDs
Affiliation (Current) 2023: 大分大学, 医学部, 助教
Affiliation (based on the past Project Information) *help 2017 – 2021: 大分大学, 医学部, 助教
2014 – 2015: 大分大学, 医学部, 助教
Review Section/Research Field
Principal Investigator
Orthopaedic surgery / Basic Section 56020:Orthopedics-related
Except Principal Investigator
Basic Section 56020:Orthopedics-related
Keywords
Principal Investigator
Ewing肉腫 / マイクロRNA / ユーイング肉腫 / 骨肉腫 / 腫瘍免疫 / 樹状細胞 / 免疫療法 / dendritic cell / foxp3 / EWS-Fli1 … More / miRNA / 融合遺伝子 / 癌 / マイクロアレイ / 遺伝子修復因子 / microRNA … More
Except Principal Investigator
Ewing肉腫 / RNA helicase A / EWS-Fli1 / RNAヘリカーゼA / 肉腫 / 染色体転座 / 融合遺伝子 / DNA二本鎖切断修復 Less
  • Research Projects

    (5 results)
  • Research Products

    (28 results)
  • Co-Researchers

    (4 People)
  •  ゲノム編集によるsyngeneic系を用いた(肉腫型)転座発がんのメカニズム解明

    • Principal Investigator
      田仲 和宏
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Oita University
  •  ユーイング肉腫におけるマイクロRNAとDNA修復機構の治療抵抗性獲得への関与Principal Investigator

    • Principal Investigator
      河野 正典
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Oita University
  •  Analyis of RNA helicase A function on Ewing's sarcoma-specific fusion gene

    • Principal Investigator
      Itonaga Ichiro
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Oita University
  •  Analysis of aberrant microRNA expression due to the type of fusion gene in Ewing's sarcoma.Principal Investigator

    • Principal Investigator
      Kawano Masanori
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Oita University
  •  Foxp3 expressed dendritic cells combined with cryoimmunology produce antitumor effects in osteosarcomaPrincipal Investigator

    • Principal Investigator
      kawano masanori
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Oita University

All 2022 2021 2019 2018 2016 2015 Other

All Journal Article Presentation

  • [Journal Article] Analysis of the signal cross talk via CCL26 in the tumor microenvironment in osteosarcoma.2021

    • Author(s)
      Kawano M, Iwasaki T, Itonaga I, Kubota Y, Tanaka K, Tsumura H.
    • Journal Title

      Scientific Reports

      Volume: 11 Pages: 18099-18099

    • DOI

      10.1038/s41598-021-97153-2

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09576, KAKENHI-PROJECT-20K09414, KAKENHI-PROJECT-21K09230
  • [Journal Article] Sensitive quantification of free pazopanib using ultra-high performance liquid chromatography coupled to tandem mass spectrometry and assessment of clinical application2021

    • Author(s)
      Matsumoto Asami、Shiraiwa Ken、Suzuki Yosuke、Tanaka Kazuhiro、Kawano Masanori、Iwasaki Tatsuya、Tanaka Ryota、Tatsuta Ryosuke、Tsumura Hiroshi、Itoh Hiroki
    • Journal Title

      Journal of Pharmaceutical and Biomedical Analysis

      Volume: 206 Pages: 114348-114348

    • DOI

      10.1016/j.jpba.2021.114348

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K09230
  • [Journal Article] Surrogacy of intermediate endpoints for overall survival in randomized controlled trials of first-line treatment for advanced soft tissue sarcoma in the pre- and post-pazopanib era: a meta-analytic evaluation2019

    • Author(s)
      Tanaka K, Kawano M, Iwasaki T, Itonaga I, Tsumura H.
    • Journal Title

      BMC Cancer

      Volume: 19 Pages: 56-56

    • DOI

      10.1186/s12885-019-5268-2

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K10866, KAKENHI-PROJECT-18K09110, KAKENHI-PROJECT-17K10971, KAKENHI-PROJECT-18K16666
  • [Journal Article] A meta-analysis of randomized controlled trials that compare standard doxorubicin with other first-line chemotherapies for advanced/metastatic soft tissue sarcomas2019

    • Author(s)
      Tanaka K, Kawano M, Iwasaki T, Itonaga I, Tsumura H.
    • Journal Title

      PLoS One.

      Volume: 14 Pages: 1-18

    • DOI

      10.1371/journal.pone.0210671

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K10866, KAKENHI-PROJECT-18K09110, KAKENHI-PROJECT-17K10971, KAKENHI-PROJECT-18K16666
  • [Journal Article] MicroRNA-20b promotes cell proliferation via targeting of TGF-β receptor II and upregulates MYC expression in Ewing's sarcoma cells2018

    • Author(s)
      Kawano M, Tanaka K, Itonaga I, Iwasaki T, Tsumura H.
    • Journal Title

      Int J Oncol

      Volume: 51(6) Pages: 1842-1850

    • DOI

      10.3892/ijo.2017.4155

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K10971, KAKENHI-PROJECT-15K10451, KAKENHI-PROJECT-16K10866
  • [Journal Article] Interaction between human osteosarcoma and mesenchymal stem cells via an interleukin-8 signaling loop in the tumor microenvironment2018

    • Author(s)
      Kawano M, Tanaka K, Itonaga I, Iwasaki T, Tsumura H.
    • Journal Title

      Cell Communication and Signaling

      Volume: 16(1) Pages: 1-11

    • DOI

      10.1186/s12964-018-0225-2

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K10971, KAKENHI-PROJECT-18K09110, KAKENHI-PROJECT-16K10866
  • [Journal Article] MicroRNA-181c prevents apoptosis by targeting of FAS receptor in Ewing’s sarcoma cells2018

    • Author(s)
      Kawano M, Tanaka K, Itonaga I, Iwasaki T, Tsumura H.
    • Journal Title

      Cancer Cell International

      Volume: 18 Pages: 1-11

    • DOI

      10.1186/s12935-018-0536-9

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K10971, KAKENHI-PROJECT-15K10451, KAKENHI-PROJECT-18K09110, KAKENHI-PROJECT-16K10866
  • [Journal Article] MicroRNA-301a promotes cell proliferation via PTEN targeting in Ewing’s sarcoma cells2016

    • Author(s)
      Kawano M, Tanaka K, Itonaga I, Iwasaki T, Tsumura H.
    • Journal Title

      Int J Oncol

      Volume: Apr;48(4): Pages: 1531-1540

    • DOI

      10.3892/ijo.2016.3379

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26670668, KAKENHI-PROJECT-26861200, KAKENHI-PROJECT-15K10451
  • [Journal Article] Dendritic Cells Combined with Immunogenic Cell Death Induced by Doxorubicin Produces Antitumor Effects in Osteosarcoma.2016

    • Author(s)
      Kawano M, Tanaka K, Itonaga I, Iwasaki T, Miyazaki M, Ikeda S, Tsumura H.
    • Journal Title

      Oncology Letters.

      Volume: 11

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26861200
  • [Journal Article] Tumor suppressive microRNA-138 inhibits metastatic potential via the targeting of focal adhesion kinase in Ewing’s sarcoma cells.2016

    • Author(s)
      Kawano M, Tanaka K, Itonaga I, Iwasaki T, Miyazaki M, Ikeda S, Tsumura H.
    • Journal Title

      Int J Oncol

      Volume: Mar;48(3): Pages: 1135-1144

    • DOI

      10.3892/ijo.2016.3317

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26670668, KAKENHI-PROJECT-26861200, KAKENHI-PROJECT-15K10451
  • [Journal Article] Dendritic Cells Combined with Anti-GITR Antibody Produce Antitumor Effects in Osteosarcoma.2015

    • Author(s)
      Kawano M, Tanaka K, Itonaga I, Iwasaki T, Miyazaki M, Ikeda S, Tsumura H
    • Journal Title

      International Journal of Oncology

      Volume: 34 Pages: 1543-1550

    • DOI

      10.3892/or.2015.4161

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K10451, KAKENHI-PROJECT-26670668, KAKENHI-PROJECT-26861200
  • [Journal Article] Tumor-suppressive microRNA-let-7a inhibits cell2015

    • Author(s)
      Iwasaki T, Tanaka K, Kawano M, Itonaga I, Tsumura H
    • Journal Title

      International Jnournal of Oncology.

      Volume: 46 Pages: 1543-1550

    • DOI

      10.3892/ijo.2015.2867

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24592250, KAKENHI-PROJECT-26670668, KAKENHI-PROJECT-26861200
  • [Journal Article] microRNA-93 promotes cell proliferation via targeting of PTEN in Osteosarcoma cells.2015

    • Author(s)
      Kawano M, Tanaka K, Itonaga I, Ikeda S, Iwasaki T, Tsumura H
    • Journal Title

      Journal of Experimental & Clinical Cancer Research.

      Volume: 34 Pages: 76-76

    • DOI

      10.1186/s13046-015-0192-z

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K10451, KAKENHI-PROJECT-26670668, KAKENHI-PROJECT-26861200
  • [Journal Article] c-Myc Represses Tumor-Suppressive microRNAs, let-7a, miR-16 and miR-29b, and Induces Cyclin D2-Mediated Cell Proliferation in Ewing's Sarcoma Cell Line.2015

    • Author(s)
      Kawano M, Tanaka K, Itonaga I, Iwasaki T, Tsumura H
    • Journal Title

      PLoS One

      Volume: 10

    • DOI

      10.1371/journal.pone.0138560

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K10451, KAKENHI-PROJECT-26670668, KAKENHI-PROJECT-26861200
  • [Journal Article] Dendritic Cells Combined with Immunogenic Cell Death Induced by Doxorubicin Exhibits Antitumor Effects for Osteosarcoma2015

    • Author(s)
      M. Kawano, K. Tanaka, I. Itonaga, T. Iwasaki, M. Miyazaki, S. Ikeda, H. Tsumura
    • Journal Title

      Oncology Letters

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26861200
  • [Presentation] Ewing 肉腫細胞における miR-152 における CDK5R1発現と腫瘍増殖能の解析2022

    • Author(s)
      河野 正典
    • Organizer
      日本サルコーマ治療研究学会学術集会
    • Data Source
      KAKENHI-PROJECT-19K09576
  • [Presentation] Ewing 肉腫細胞における miR-152 における CDK5R1発現と腫瘍増殖能の解析2022

    • Author(s)
      河野正典
    • Organizer
      第5回 日本サルコーマ治療研究学会学術集会
    • Data Source
      KAKENHI-PROJECT-20K09414
  • [Presentation] Ewing 肉腫細胞における skp2 による p27 発現抑制と腫瘍増殖能の解析2021

    • Author(s)
      河野正典
    • Organizer
      第54回 日本整形外科学会 骨・軟部腫瘍学術集会
    • Data Source
      KAKENHI-PROJECT-20K09414
  • [Presentation] 日本整形外科学会基礎学術集会2021

    • Author(s)
      河野 正典
    • Organizer
      第36回 日本整形外科学会基礎学術集会
    • Data Source
      KAKENHI-PROJECT-19K09576
  • [Presentation] Ewing 肉腫細胞における skp2 による p27 発現抑制と腫瘍増殖能の解析2021

    • Author(s)
      河野 正典
    • Organizer
      第54回 日本整形外科学会 骨・軟部腫瘍学術集会
    • Data Source
      KAKENHI-PROJECT-19K09576
  • [Presentation] Ewing肉腫細胞におけるFbxw7によるMyc発現調節と腫瘍増殖能の解析2021

    • Author(s)
      河野正典
    • Organizer
      第36回 日本整形外科学会基礎学術集会
    • Data Source
      KAKENHI-PROJECT-20K09414
  • [Presentation] microRNA-301a promotes cell proliferation via targeting of PTEN in Ewing’s sarcoma cells2015

    • Author(s)
      M Kawano, K Tanaka, I. Itonaga, T. Iwasaki, H. Tsumura.
    • Organizer
      Japan Muscular Skeletal Tumor Society Meeting
    • Place of Presentation
      かがわ国際会議場(香川県、高松市)
    • Year and Date
      2015-07-10
    • Data Source
      KAKENHI-PROJECT-26861200
  • [Presentation] microRNA-93 promotes cell proliferation via targeting of PTEN in Osteosarcoma cells.2015

    • Author(s)
      M Kawano, K Tanaka, I. Itonaga, T. Iwasaki, H. Tsumura.
    • Organizer
      Annual research meeting of the Japanese orthopedic association
    • Place of Presentation
      富山国際会議場(富山県、富山市)
    • Year and Date
      2015-10-22
    • Data Source
      KAKENHI-PROJECT-26861200
  • [Presentation] Tumor-suppressive microRNA-let7a inhibits cancer cell proliferation targeting the E2F2 oncogene in osteosarcoma

    • Author(s)
      Masanori Kawano
    • Organizer
      日本癌学会
    • Place of Presentation
      パシフィコ横浜(神奈川県、横浜市)
    • Year and Date
      2014-09-25 – 2014-09-28
    • Data Source
      KAKENHI-PROJECT-26861200
  • [Presentation] microRNA-301a promotes cell proliferation via targeting of PTEN in Ewing’s sarcoma cells.

    • Author(s)
      Masanori Kawano
    • Organizer
      日本整形外科学会骨軟部腫瘍学会
    • Place of Presentation
      かがわ国際会議場(香川県、香川市)
    • Year and Date
      2015-07-17 – 2015-07-18
    • Data Source
      KAKENHI-PROJECT-26861200
  • [Presentation] Tumor-suppressive microRNA-let7a inhibits cancer cell proliferation targeting the E2F2 oncogene in osteosarcoma

    • Author(s)
      Masanori Kawano
    • Organizer
      日本整形外科学会骨軟部腫瘍学会
    • Place of Presentation
      大阪国際会議場(大阪府、大阪市)
    • Year and Date
      2014-07-17 – 2014-07-18
    • Data Source
      KAKENHI-PROJECT-26861200
  • [Presentation] Tumor-suppressive microRNA-let7a inhibits cancer cell proliferation targeting the E2F2 oncogene in osteosarcoma

    • Author(s)
      Masanori Kawano
    • Organizer
      Orthopaedic Research Society
    • Place of Presentation
      MGM Grand Hotel (Unites States, Las vegas)
    • Year and Date
      2015-03-27 – 2015-03-30
    • Data Source
      KAKENHI-PROJECT-26861200
  • [Presentation] microRNA-138 inhibits metastatic potential of Ewing’s sarcoma cells via targeting of focal adhesion kinase

    • Author(s)
      Masanori Kawano
    • Organizer
      日本整形外科学会基礎学術集会
    • Place of Presentation
      城山観光ホテル(鹿児島県、鹿児島市)
    • Year and Date
      2014-10-09 – 2014-10-10
    • Data Source
      KAKENHI-PROJECT-26861200
  • 1.  田仲 和宏 (10274458)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 13 results
  • 2.  Itonaga Ichiro (10295181)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 12 results
  • 3.  織田 信弥 (40333372)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  岩崎 達也
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results

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