Kawano Masanori 河野正典

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kawano masanori 河野正典

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Researcher Number	30571773
Other IDs
Affiliation (Current)	2023: 大分大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2017 – 2021: 大分大学, 医学部, 助教 2014 – 2015: 大分大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Orthopaedic surgery / Basic Section 56020:Orthopedics-related Except Principal Investigator Basic Section 56020:Orthopedics-related
Keywords	Principal Investigator Ewing肉腫 / マイクロRNA / ユーイング肉腫 / 骨肉腫 / 腫瘍免疫 / 樹状細胞 / 免疫療法 / dendritic cell / foxp3 / EWS-Fli1 … More / miRNA / 融合遺伝子 / 癌 / マイクロアレイ / 遺伝子修復因子 / microRNA … More Except Principal Investigator Ewing肉腫 / RNA helicase A / EWS-Fli1 / RNAヘリカーゼA / 肉腫 / 染色体転座 / 融合遺伝子 / DNA二本鎖切断修復 Less

ゲノム編集によるsyngeneic系を用いた(肉腫型)転座発がんのメカニズム解明
- Principal Investigator
  
  田仲和宏
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Oita University
ユーイング肉腫におけるマイクロRNAとDNA修復機構の治療抵抗性獲得への関与Principal Investigator
- Principal Investigator
  
  河野正典
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Oita University
Analyis of RNA helicase A function on Ewing's sarcoma-specific fusion gene
- Principal Investigator
  
  Itonaga Ichiro
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Oita University
Analysis of aberrant microRNA expression due to the type of fusion gene in Ewing's sarcoma.Principal Investigator
- Principal Investigator
  
  Kawano Masanori
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Oita University
Foxp3 expressed dendritic cells combined with cryoimmunology produce antitumor effects in osteosarcomaPrincipal Investigator
- Principal Investigator
  
  kawano masanori
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Oita University

All 2022 2021 2019 2018 2017 2016 2015 Other

All Journal Article Presentation

[Journal Article] Analysis of the signal cross talk via CCL26 in the tumor microenvironment in osteosarcoma2021
- Author(s)
  Kawano M, Iwasaki T, Itonaga I, Kubota Y, Tanaka K, Tsumura H.
- Journal Title
  
  Sci Rep
  
  Volume: 11 Issue: 1 Pages: 18099-18099
- DOI
  10.1038/s41598-021-97153-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09576, KAKENHI-PROJECT-20K09414, KAKENHI-PROJECT-21K09230
[Journal Article] Sensitive quantification of free pazopanib using ultra-high performance liquid chromatography coupled to tandem mass spectrometry and assessment of clinical application2021
- Author(s)
  Matsumoto Asami、Shiraiwa Ken、Suzuki Yosuke、Tanaka Kazuhiro、Kawano Masanori、Iwasaki Tatsuya、Tanaka Ryota、Tatsuta Ryosuke、Tsumura Hiroshi、Itoh Hiroki
- Journal Title
  
  Journal of Pharmaceutical and Biomedical Analysis
  
  Volume: 206 Pages: 114348-114348
- DOI
  10.1016/j.jpba.2021.114348
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K09230
[Journal Article] Surrogacy of intermediate endpoints for overall survival in randomized controlled trials of first-line treatment for advanced soft tissue sarcoma in the pre- and post-pazopanib era: a meta-analytic evaluation.2019
- Author(s)
  Tanaka K, Kawano M, Iwasaki T, Itonaga I, Tsumura H.
- Journal Title
  
  BMC Cancer.
  
  Volume: 19 Issue: 1 Pages: 56-56
- DOI
  10.1186/s12885-019-5268-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10866, KAKENHI-PROJECT-18K09110, KAKENHI-PROJECT-17K10971, KAKENHI-PROJECT-18K16666
[Journal Article] A meta-analysis of randomized controlled trials that compare standard doxorubicin with other first-line chemotherapies for advanced/metastatic soft tissue sarcomas.2019
- Author(s)
  Tanaka K, Kawano M, Iwasaki T, Itonaga I, Tsumura H.
- Journal Title
  
  PLoS One
  
  Volume: 14 Issue: 1 Pages: 1-18
- DOI
  10.1371/journal.pone.0210671
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10866, KAKENHI-PROJECT-18K09110, KAKENHI-PROJECT-17K10971, KAKENHI-PROJECT-18K16666
[Journal Article] Interaction between human osteosarcoma and mesenchymal stem cells via an interleukin-8 signaling loop in the tumor microenvironment.2018
- Author(s)
  Kawano M, Tanaka K, Itonaga I, Iwasaki T, Tsumura H.
- Journal Title
  
  Cell Commun Signal.
  
  Volume: 16(1) Issue: 1 Pages: 13-13
- DOI
  10.1186/s12964-018-0225-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10971, KAKENHI-PROJECT-18K09110, KAKENHI-PROJECT-16K10866
[Journal Article] MicroRNA-181c prevents apoptosis by targeting of FAS receptor in Ewing's sarcoma cells.2018
- Author(s)
  Kawano M, Tanaka K, Itonaga I, Iwasaki T, Tsumura H.
- Journal Title
  
  Cancer Cell Int.
  
  Volume: 18 Issue: 1 Pages: 37-37
- DOI
  10.1186/s12935-018-0536-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10971, KAKENHI-PROJECT-15K10451, KAKENHI-PROJECT-18K09110, KAKENHI-PROJECT-16K10866
[Journal Article] MicroRNA-20b promotes cell proliferation via targeting of TGF-β receptor II and upregulates MYC expression in Ewing's sarcoma cells.2017
- Author(s)
  Kawano M, Tanaka K, Itonaga I, Iwasaki T, Tsumura H.
- Journal Title
  
  Int J Oncol.
  
  Volume: 51(6) Issue: 6 Pages: 1842-1850
- DOI
  10.3892/ijo.2017.4155
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10971, KAKENHI-PROJECT-15K10451, KAKENHI-PROJECT-16K10866
[Journal Article] MicroRNA-301a promotes cell proliferation via PTEN targeting in Ewing's sarcoma cells.2016
- Author(s)
  Kawano M, Tanaka K, Itonaga I, Iwasaki T, Tsumura H.
- Journal Title
  
  International Jnournal of Oncology.
  
  Volume: Apr;48(4): Issue: 4 Pages: 1531-1540
- DOI
  10.3892/ijo.2016.3379
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26670668, KAKENHI-PROJECT-26861200, KAKENHI-PROJECT-15K10451
[Journal Article] Dendritic Cells Combined with Immunogenic Cell Death Induced by Doxorubicin Produces Antitumor Effects in Osteosarcoma.2016
- Author(s)
  Kawano M, Tanaka K, Itonaga I, Iwasaki T, Miyazaki M, Ikeda S, Tsumura H.
- Journal Title
  
  Oncology Letters.
  
  Volume: 11
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26861200
[Journal Article] Tumor suppressive microRNA-138 inhibits metastatic potential via the targeting of focal adhesion kinase in Ewing's sarcoma cells.2016
- Author(s)
  Kawano M, Tanaka K, Itonaga I, Iwasaki T, Miyazaki M, Ikeda S, Tsumura H.
- Journal Title
  
  International Jnournal of Oncology.
  
  Volume: Mar;48(3): Issue: 3 Pages: 1135-1144
- DOI
  10.3892/ijo.2016.3317
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26670668, KAKENHI-PROJECT-26861200, KAKENHI-PROJECT-15K10451
[Journal Article] Dendrotic cells combined with anti-GITR antibody produce antitumor effects in osteosarcoma.2015
- Author(s)
  Kawano M, Tanaka K, Itonaga I, Iwasaki T, Miyazaki M, Ikeda S, Tsumura H
- Journal Title
  
  Oncol Rep
  
  Volume: 34 Issue: 4 Pages: 1995-2001
- DOI
  10.3892/or.2015.4161
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10451, KAKENHI-PROJECT-26670668, KAKENHI-PROJECT-26861200
[Journal Article] Tumor-suppressive microRNA-let-7a inhibits cell proliferation via targeting of E2F2 in osteosarcoma cells.2015
- Author(s)
  Iwasaki T, Tanaka K, Kawano M, Itonaga I, Tsumura H
- Journal Title
  
  Int J Oncol
  
  Volume: 46 Issue: 4 Pages: 1543-1550
- DOI
  10.3892/ijo.2015.2867
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24592250, KAKENHI-PROJECT-26670668, KAKENHI-PROJECT-26861200
[Journal Article] microRNA-93 promotes cell proliferation via targeting of PTEN in osteosarcoma cells.2015
- Author(s)
  Kawano M, Tanaka K, Itonaga I, Ikeda S, Iwasaki T, Tsumura H
- Journal Title
  
  J Exp Clin Cancer Res
  
  Volume: 34 Issue: 1 Pages: 76-76
- DOI
  10.1186/s13046-015-0192-z
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K10451, KAKENHI-PROJECT-26670668, KAKENHI-PROJECT-26861200
[Journal Article] c-MYc represses tumor-suppressive microRNAs, let-7a, miR-16 and miR-29b, and induces cyclin D2-mediated cell proliferation in Ewing’s sarcoma cell line.2015
- Author(s)
  Kawano M, Tanaka K, Itonaga I, Iwasaki T, Tsumura H
- Journal Title
  
  Plos One
  
  Volume: 10 Issue: 9 Pages: e0138560-e0138560
- DOI
  10.1371/journal.pone.0138560
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10451, KAKENHI-PROJECT-26670668, KAKENHI-PROJECT-26861200
[Journal Article] Dendritic Cells Combined with Immunogenic Cell Death Induced by Doxorubicin Exhibits Antitumor Effects for Osteosarcoma2015
- Author(s)
  M. Kawano, K. Tanaka, I. Itonaga, T. Iwasaki, M. Miyazaki, S. Ikeda, H. Tsumura
- Journal Title
  
  Oncology Letters
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26861200
[Presentation] Ewing 肉腫細胞における miR-152 における CDK5R1発現と腫瘍増殖能の解析2022
- Author(s)
  河野　正典
- Organizer
  日本サルコーマ治療研究学会学術集会
- Data Source
  KAKENHI-PROJECT-19K09576
[Presentation] Ewing 肉腫細胞における miR-152 における CDK5R1発現と腫瘍増殖能の解析2022
- Author(s)
  河野正典
- Organizer
  第5回　日本サルコーマ治療研究学会学術集会
- Data Source
  KAKENHI-PROJECT-20K09414
[Presentation] Ewing 肉腫細胞における skp2 による p27 発現抑制と腫瘍増殖能の解析2021
- Author(s)
  河野正典
- Organizer
  第54回　日本整形外科学会　骨・軟部腫瘍学術集会
- Data Source
  KAKENHI-PROJECT-20K09414
[Presentation] 日本整形外科学会基礎学術集会2021
- Author(s)
  河野　正典
- Organizer
  第36回　日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-19K09576
[Presentation] Ewing 肉腫細胞における skp2 による p27 発現抑制と腫瘍増殖能の解析2021
- Author(s)
  河野　正典
- Organizer
  第54回　日本整形外科学会　骨・軟部腫瘍学術集会
- Data Source
  KAKENHI-PROJECT-19K09576
[Presentation] Ewing肉腫細胞におけるFbxw7によるMyc発現調節と腫瘍増殖能の解析2021
- Author(s)
  河野正典
- Organizer
  第36回　日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-20K09414
[Presentation] microRNA-301a promotes cell proliferation via targeting of PTEN in Ewing’s sarcoma cells2015
- Author(s)
  M Kawano, K Tanaka, I. Itonaga, T. Iwasaki, H. Tsumura.
- Organizer
  Japan Muscular Skeletal Tumor Society Meeting
- Place of Presentation
  かがわ国際会議場（香川県、高松市）
- Year and Date
  2015-07-10
- Data Source
  KAKENHI-PROJECT-26861200
[Presentation] microRNA-93 promotes cell proliferation via targeting of PTEN in Osteosarcoma cells.2015
- Author(s)
  M Kawano, K Tanaka, I. Itonaga, T. Iwasaki, H. Tsumura.
- Organizer
  Annual research meeting of the Japanese orthopedic association
- Place of Presentation
  富山国際会議場（富山県、富山市）
- Year and Date
  2015-10-22
- Data Source
  KAKENHI-PROJECT-26861200
[Presentation] Tumor-suppressive microRNA-let7a inhibits cancer cell proliferation targeting the E2F2 oncogene in osteosarcoma
- Author(s)
  Masanori Kawano
- Organizer
  日本癌学会
- Place of Presentation
  パシフィコ横浜（神奈川県、横浜市）
- Year and Date
  2014-09-25 – 2014-09-28
- Data Source
  KAKENHI-PROJECT-26861200
[Presentation] microRNA-301a promotes cell proliferation via targeting of PTEN in Ewing’s sarcoma cells.
- Author(s)
  Masanori Kawano
- Organizer
  日本整形外科学会骨軟部腫瘍学会
- Place of Presentation
  かがわ国際会議場（香川県、香川市）
- Year and Date
  2015-07-17 – 2015-07-18
- Data Source
  KAKENHI-PROJECT-26861200
[Presentation] Tumor-suppressive microRNA-let7a inhibits cancer cell proliferation targeting the E2F2 oncogene in osteosarcoma
- Author(s)
  Masanori Kawano
- Organizer
  日本整形外科学会骨軟部腫瘍学会
- Place of Presentation
  大阪国際会議場（大阪府、大阪市）
- Year and Date
  2014-07-17 – 2014-07-18
- Data Source
  KAKENHI-PROJECT-26861200
[Presentation] Tumor-suppressive microRNA-let7a inhibits cancer cell proliferation targeting the E2F2 oncogene in osteosarcoma
- Author(s)
  Masanori Kawano
- Organizer
  Orthopaedic Research Society
- Place of Presentation
  MGM Grand Hotel (Unites States, Las vegaｓ）
- Year and Date
  2015-03-27 – 2015-03-30
- Data Source
  KAKENHI-PROJECT-26861200
[Presentation] microRNA-138 inhibits metastatic potential of Ewing’s sarcoma cells via targeting of focal adhesion kinase
- Author(s)
  Masanori Kawano
- Organizer
  日本整形外科学会基礎学術集会
- Place of Presentation
  城山観光ホテル（鹿児島県、鹿児島市）
- Year and Date
  2014-10-09 – 2014-10-10
- Data Source
  KAKENHI-PROJECT-26861200

1. 田仲和宏 (10274458)

# of Collaborated Projects: 3 results

# of Collaborated Products: 10 results
2. Itonaga Ichiro (10295181)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
3. 織田信弥 (40333372)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Kawano Masanori 河野 正典

kawano masanori 河野 正典

Research Projects

Research Products

Co-Researchers

ゲノム編集によるsyngeneic系を用いた(肉腫型)転座発がんのメカニズム解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ユーイング肉腫におけるマイクロRNAとDNA修復機構の治療抵抗性獲得への関与Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analyis of RNA helicase A function on Ewing's sarcoma-specific fusion gene

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of aberrant microRNA expression due to the type of fusion gene in Ewing's sarcoma.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Foxp3 expressed dendritic cells combined with cryoimmunology produce antitumor effects in osteosarcomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Analysis of the signal cross talk via CCL26 in the tumor microenvironment in osteosarcoma2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Sensitive quantification of free pazopanib using ultra-high performance liquid chromatography coupled to tandem mass spectrometry and assessment of clinical application2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Surrogacy of intermediate endpoints for overall survival in randomized controlled trials of first-line treatment for advanced soft tissue sarcoma in the pre- and post-pazopanib era: a meta-analytic evaluation.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A meta-analysis of randomized controlled trials that compare standard doxorubicin with other first-line chemotherapies for advanced/metastatic soft tissue sarcomas.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Interaction between human osteosarcoma and mesenchymal stem cells via an interleukin-8 signaling loop in the tumor microenvironment.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] MicroRNA-181c prevents apoptosis by targeting of FAS receptor in Ewing's sarcoma cells.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] MicroRNA-20b promotes cell proliferation via targeting of TGF-β receptor II and upregulates MYC expression in Ewing's sarcoma cells.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] MicroRNA-301a promotes cell proliferation via PTEN targeting in Ewing's sarcoma cells.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Dendritic Cells Combined with Immunogenic Cell Death Induced by Doxorubicin Produces Antitumor Effects in Osteosarcoma.2016

Author(s)

Journal Title

Data Source

[Journal Article] Tumor suppressive microRNA-138 inhibits metastatic potential via the targeting of focal adhesion kinase in Ewing's sarcoma cells.2016

Kawano Masanori 河野正典

kawano masanori 河野正典