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nagane yuriko  長根 百合子

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NAGANE Yuriko  長根 百合子

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Researcher Number 10306003
Other IDs
Affiliation (Current) 2025: 公益財団法人総合花巻病院(臨床研究部), 脳神経内科, 脳神経内科部長
Affiliation (based on the past Project Information) *help 2006: 岩手医大, 医学部, 助手
2005: 岩手医科大学, 医学部・専門医員
1998 – 2004: 岩手医科大学, 医学部, 助手
Review Section/Research Field
Principal Investigator
Neurology
Except Principal Investigator
Neurology
Keywords
Principal Investigator
thymus / CD44 / dendritic Cell / Toll like receptor / myasthenia gravis / FK506 / IL-2産生能 / 重症筋無力症
Except Principal Investigator
α7nAChR / PC12 … More / aging / neurite outgrowth / cell cycle / tau / Hypoxia / Cell cycle / ERK / human brain / extracellular-signal-regulated kinase / cDNA array / 老化 / ニューロン / APP / RAGE / transcription / promoter / methylcytosines / Protein kinase Cδ / Neurite outgrowth / Extracellular-signal-regulated kinase / Angiotensin II / Neuronal damage / DNA fragmentation / Akt / cyclin-dependent kinase 5 / p35 / extracellular-signal-regulated kianse / α7サブタイプ / ニコチン性アセチルコリン受容体 / Cell death / proten kinase C δ / candesartan / AT2 / AT1 / protein kinase Cδ / hypoxia / angiotensin II / リン酸化 / アセチルコリン受容体 / DNAアレイ / α7nAchR / 転写調節領域 / タウ蛋白 / アミロイド前駆体蛋白 / bisulfite法 / 加齢 / プロモーター領域 / メチルシトシン / 補体 / α7サブユニット / ニコチン性Ach受容体 Less
  • Research Projects

    (5 results)
  • Research Products

    (22 results)
  • Co-Researchers

    (5 People)
  •  重症筋無力症における胸腺内病態とTolllike receptor発現様式の関連Principal Investigator

    • Principal Investigator
      長根 百合子
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Neurology
    • Research Institution
      Iwate Medical University
  •  末梢血単核球IL-2産生能高値の重症筋無力症例の病態と免疫抑制剤FK506の効果Principal Investigator

    • Principal Investigator
      長根 百合子
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Neurology
    • Research Institution
      Iwate Medical University
  •  Effects of nicotinic acetylcholine receptor overexpression in neuronal cells.

    • Principal Investigator
      UTSUGISAWA Kimiaki
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Iwate Medical University
  •  Gene expression profile of aging human brain and its in vitro model

    • Principal Investigator
      TOHGI Hideo
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurology
    • Research Institution
      Iwate Medical University
  •  Changes with age in DNA methylation and transcription in human cerebral cortex.

    • Principal Investigator
      TOHGI Hideo
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Neurology
    • Research Institution
      Iwate Medical University

All 2005 2004 2003 2002

All Journal Article

  • [Journal Article] Efficacy of low-dose FK506 in the treatment of myasthenia gravis -A randomized pilot study-2005

    • Author(s)
      Nagane Y, Utsugisawa K, et al.
    • Journal Title

      Eur Neurol (in press)

    • Data Source
      KAKENHI-PROJECT-15790454
  • [Journal Article] Efficacy of low-dose FK506 in the treatment of myasthenia gravis -A randomized pilot study-2005

    • Author(s)
      Y.Nagane, K.Utsugisawa, D.Obara, R.Kondoh, Y.Terayama
    • Journal Title

      Eur Neurol (in press)

    • Data Source
      KAKENHI-PROJECT-14570614
  • [Journal Article] Candesartan prevents angiotensin II -induced facilitation of hypoxic neuronal damage through PKC δ inhibition.2005

    • Author(s)
      K.Utsugisawa, Y.Nagane, T.Utsugisawa, D.Obara, Y.Terayama
    • Journal Title

      Mol Brain Res in press

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14570614
  • [Journal Article] Perivascular infiltrate of memory lymphocytes and mature dendritic cells in MG thymoma2005

    • Author(s)
      Nagane Y, Utsugisawa K et al.
    • Journal Title

      Neurology 65

      Pages: 770-772

    • Data Source
      KAKENHI-PROJECT-17790588
  • [Journal Article] Efficacy of low-dose FK506 in the treatment of myasthenia gravis-A randomized pilot study-2005

    • Author(s)
      Y.Nagane, K.Utsugisawa, D.Obara, R.Kondoh, Y.Terayama
    • Journal Title

      Eur Neurol in press

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14570614
  • [Journal Article] Candesartan prevents angiotensin II-induced facilitation of hypoxic neuronal damage through PKC δ inhibition.2005

    • Author(s)
      K.Utsugisawa, Y.Nagane, T.Utsugisawa, D.Obara, Y.Terayama.
    • Journal Title

      Mol Brain Res (in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14570614
  • [Journal Article] Efficacy of low dose FK506 in the treatment of myasthenia gravis - A randomized pilot study2005

    • Author(s)
      Nagane Y, Utsugisawa K et al.
    • Journal Title

      Eur Neurol 53

      Pages: 146-150

    • Data Source
      KAKENHI-PROJECT-17790588
  • [Journal Article] Candesartan prevents angiotensin II-induced facilitation of hypoxic neuronal damage through PKCδinhibition.2004

    • Author(s)
      K.Utsugisawa, Y.Nagane, T.Utsugisawa, D.Obara, Y.Terayama.
    • Journal Title

      Mol Brain Res (in press)

    • Data Source
      KAKENHI-PROJECT-14570614
  • [Journal Article] Clinical characteristics and efficacy of FK506 in myasthenia gravis patients with high Interleukin-2 productivity in peripheral blood mononuclear cells.2004

    • Author(s)
      K.Utsugisawa, Y.Nagane, Y.Terayama.
    • Journal Title

      Neurology 62

    • Data Source
      KAKENHI-PROJECT-14570614
  • [Journal Article] Effects of FK506 on myasthenia gravis patients with high interleukin-2 productivity in peripheral blood mononuclear cells.2003

    • Author(s)
      Utsugisawa K, Nagane Y, Yonezawa H, Obara D, Kondoh R, Tohgi H
    • Journal Title

      Muscle Nerve 27

      Pages: 245-248

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14570614
  • [Journal Article] Interleukin-2 production by peripheral blood mononuclear cells from patients with myasthenia gravis.2003

    • Author(s)
      Utsugisawa K, Nagane Y et al.
    • Journal Title

      Eur Neurol 49・3

      Pages: 160-163

    • Data Source
      KAKENHI-PROJECT-15790454
  • [Journal Article] Effects of FK506 on myasthenia gravis with high interleukin-2 productivity in peripheral blood mononuclear cells.2003

    • Author(s)
      Utsugisawa K, Nagane Y et al.
    • Journal Title

      Muscle Nerve 27・2

      Pages: 245-248

    • Data Source
      KAKENHI-PROJECT-15790454
  • [Journal Article] Interleukin-2 production by peripheral blood mononuclear cells from patients with myasthenia gravis.2003

    • Author(s)
      Utsugisawa K, Nagane Y, Obara D, Kondoh R, Yonezawa H, Tohgi H
    • Journal Title

      Fur Neurol 49

      Pages: 160-163

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14570614
  • [Journal Article] Dendritic cells in hyperplastic thymuses from patents with myasthenia gravis.2003

    • Author(s)
      Nagane Y, Utsugisawa K, et al.
    • Journal Title

      Muscle Nerve 27・5

      Pages: 582-589

    • Data Source
      KAKENHI-PROJECT-15790454
  • [Journal Article] Dendritic cells in hyperplastic thymuses from patients with myasthenia gravis.2003

    • Author(s)
      Nagane Y, Utsugisawa K, Obara D, Yamagata M, Tohgi H
    • Journal Title

      Muscle Nerve 27

      Pages: 582-589

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14570614
  • [Journal Article] Hypoxic condition interferes with phosphorylation of Akt atThr308 in cultured rat PC12 cells.2002

    • Author(s)
      Obara D, Utsugisawa K, Nagane Y, Tohgi H
    • Journal Title

      Neurosci Lett 332

      Pages: 167-170

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14570614
  • [Journal Article] Over-expression of α7 nicotinic acetyicholine receptor induces sustained ERK phosphorylation and N-cadherin expression in PC12 cells.2002

    • Author(s)
      Utsugisawa K, Nagane Y, Obara D, Toligi H
    • Journal Title

      Mol Brain Res 106

      Pages: 88-93

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14570614
  • [Journal Article] The Effect of Combined Therapy with Immunoadsorption andHigh-Dose Intravenous Methyiprednisolone on Myasthenia Gravis.2002

    • Author(s)
      Munakata R, Utsugisawa K, Nagane Y, Yamagata M, Oikawa M, Obara D, Tohgi H
    • Journal Title

      Eur Neurol 48

      Pages: 115-117

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14570614
  • [Journal Article] Over-expression of α7 nicotinic acetyicholine receptor preventsGi-arrest and DNA fragmentation in PC12 cells after hypoxia.2002

    • Author(s)
      Utsugisawa K, Nagane Y, Obara D, Tohgi H
    • Journal Title

      J Neurochem 81

      Pages: 497-505

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14570614
  • [Journal Article] Over-expression of α7 nicotinic acetylcholine receptor induces sustained ERK phosphorylation and N-cadherin expression in PC12 cells.2002

    • Author(s)
      Utsugisawa K, Nagane Y, Obara D, Tohgi H
    • Journal Title

      Mol Brain Res 106

      Pages: 88-93

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14570614
  • [Journal Article] Over-expression of α7 nicotinic acetylcholine receptor prevents G1-arrest and DNA fragmentation in PC12 cells after hypoxia.2002

    • Author(s)
      Utsugisawa K, Nagane Y, Obara D, Tohgi H
    • Journal Title

      J Neurochem 81

      Pages: 497-505

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14570614
  • [Journal Article] Hypoxic condition interferes with phosphorylation of Akt at Thr^<308> in cultured rat PC12 cells.2002

    • Author(s)
      Obara D, Utsugisawa K, Nagane Y, Tohgi H
    • Journal Title

      Neurosci Lett 332

      Pages: 167-170

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14570614
  • 1.  UTSUGISAWA Kimiaki (00244913)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 16 results
  • 2.  ABE Takashi (30202667)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 3.  TOHGI Hideo (90155490)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  TAKAHASHI Satoshi (50216719)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  YAMAGATA Munehisa (00295974)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results

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