Shibata Masa-Aki 柴田雅朗

… Alternative Names

SHIBATA Masa-aki 柴田雅朗

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Researcher Number	10319543
Other IDs
External Links
Affiliation (Current)	2025: 大阪医科薬科大学, 医学部, 功労教授
Affiliation (based on the past Project Information) *help	2022 – 2023: 大阪医科薬科大学, 医学部, 功労教授 2021: 大阪医科薬科大学, 医学部, 准教授 2016 – 2020: 大阪医科大学, 医学部, 准教授 2010 – 2015: 大阪保健医療大学, 保健医療学部, 教授 2013: 大阪保健医療大学, 大学院・保健医療学研究科, 教授 … More 2012: 大阪保健医療大学, 保健医療部, 教授 2007 – 2009: Osaka Medical College, Department of Anatomy, Associate Professor 2001 – 2006: Osaka Medical College, Faculty of Medicine Associate Professor, 医学部, 助教授 2000: 大阪医科大学, 医学部, 講師 Less
Review Section/Research Field	Principal Investigator General surgery / Basic Section 55010:General surgery and pediatric surgery-related / Urology Except Principal Investigator General surgery / Basic Section 55010:General surgery and pediatric surgery-related / Thoracic surgery / Basic veterinary science/Basic zootechnical science
Keywords	Principal Investigator 転移 / 乳癌 / siRNA / マウス / VEGF-C / Mouse / Angiogenesis / Cancer gene therapy / 遺伝子治療 / 抗腫瘍効果 … More / nSM2 / Smpd3 / エクソソーム / 転移抑制 / Metastasis / VEGF-A / Human umbilical vascular endothelial cell / Electrogene transfer / Mammary carcinoma / Angiostatin / Endostatin / Caspase / Electroporation / アポトーシス / リンパ管新生 / 乳腺外科学 / CRISPR/Cas9 / ノックダウン / ノックアウト / ｎSM2 / 乳癌転移 / 抗脈管新生因子 / マイクロRNA / 転移前ニッチ / miRNA / mouse / Mammary carcioma / hematogeneous metastasis / Lymphatic metastasis / Mammary cancer / Lymphangiogenesis / 血行性転移 / リンパ行性転移 / Elrctrogene transfer / Mammry carcinoma / Non-virus vector / Mitochondrial pathway / Apoptosis / HSVtk / Urinary bladder cancer / in vivo / in vitro / Electro-gene transfer / 非ウイルスベクター / ラット / bax / 単純性ヘルペスチミジンキナーゼ / ミトコンドリア膜電位 / 非ウィルスベクター / ミトコンドリア経路 / カスパーゼ / エレクトロポレーション / 単純性ヘルペスウイルス・サイミジンキナーゼ / 膀胱癌 / テネイシン抗体 / リンパ管侵襲 / 血管新生 / α-マンゴスチン / テネイシン / 複合治療 / 抗体医薬 / 治療 / マンゴスチン / テネイシンC抗体 / VEGFR-3デコイ / リンパ転移 / リンパ節転移 / デコイベクター / VEGFR3 / SATB1 / VEGFR-2受容体デコイ / VEGFR-2 / VEGF-D / 癌遺伝子治療 … More Except Principal Investigator リンパ行性転移 / VEGF-C / 乳癌 / microRNA / miRNA / 外科 / p53 / 乳癌細胞 / 低酸素 / exosome / microvesicle / リンパ管新生 / LYVE-1 / 化学修飾 / 創薬 / 切除不能 / 酸化還元 / DDS / 核酸創薬 / ドラッグデリバリーシステム / 核酸医薬 / 移植・再生医療 / 遺伝子 / 発現抑制 / 癌 / miR27b / 高転移性乳癌 / autocrine / 細胞外小胞 / microRNA-27 / hypoxia / Exosome / 乳がん / translational research / pathology / cell-cell interactions / immunotherapy / tenascin / extracellular matrix / anti-cancer treatment / surgery / トランスレーショナルリサーチ / 病理学 / 細胞間相互作用 / 抗体治療 / テネイシン / 細胞外マトリックス / 生体分子 / Ca^<2+>-ATPase inhibitor / Intracellular Ca^<2+> chelator / caspase family / human lung cancer cells / intracellular Ca^<2+> concentrations / heat-shock / Apoptosis / Caspase-3 / AM / BAPTA / 細胞内Ca_<2+>濃度 / 温熱誘導アポトーシス / デス・レセプター経路 / ミトコンドリア経路 / 小胞体Ca^<2+>-ATPaseの阻害剤 / カルシウム・キレート剤 / カスパーゼファミリー / ヒト肺癌細胞 / 細胞内カルシウムイオン濃度 / 温熱 / アポトーシス / metastasis / lymphangiogenesis / precursorVEGF-C / matureVEGF-C / リンパ管形成 / exosomes / 転移性の差異 / 乳癌のリンパ行性転移 / microvesicles / オートクライン / マウス乳癌細胞 / 妊娠生理 / 脂質代謝 / 流産 / マウス / 免疫 / 脂質 / 補体 / 胎盤 / リン酸化VEGFR-3 / Podolanin / VEGFR-3 / Prox-1 / 遺伝子導入 / リンパ管リプログラミング / マウス乳癌 / 癌治療 / Microvesicles / CEACAM-1 / 血管新生 / リンパ節 / Vescular endothelial growth factor C(VEGF-C) / CD44 / マウス移植乳癌 / CD44、LYVE-1 / ヒアルロン酸 / リンパ節転移 / リンパ管浸潤 / リンパ管再生 Less

Development of therapeutic strategies for the realization of tumor suppressive microRNA replacement therapy for refractory solid tumors
- Principal Investigator
  
  谷口高平
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Osaka Medical and Pharmaceutical University
Suppression of mammary cancer metastasis by exosome-associated gene deletion by CRISPR/Cas9 systemPrincipal Investigator
- Principal Investigator
  
  柴田雅朗
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Osaka Medical and Pharmaceutical University
Combination therapy with inhibition of exosome production and anti-vasculogenesis for suppression of mammary cancer metastasisPrincipal Investigator
- Principal Investigator
  
  Shibata Masa-Aki
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Osaka Medical and Pharmaceutical University
Highly metastatic mouse mammary carcinoma cells decrease suppressive miRNAs via exosome
- Principal Investigator
  
  ITO YUKO
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Osaka Medical College
Mouse mammary carcinoma cell lines release microvesicles containing precurcer VEGF-C
- Principal Investigator
  
  Ito Yuko
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Osaka Medical College
Treatment with tenascin C antibody and/or alpha-mangostin reduces tumor growth and lymph node metastasis in a model of metastatic mammary cancerPrincipal Investigator
- Principal Investigator
  
  SHIBATA Masaaki
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Osaka Health Science University
Reproductive roles of the adipsin/ASP pathway mediated by immunological and lipid methabolic effects
- Principal Investigator
  
  KEN TAKESHI Kusakabe
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Basic veterinary science/Basic zootechnical science
- Research Institution
  Yamaguchi University
CEACAM-1 promotes lymphangiogenesis and angiogenesis in the inoculated mouse mammary carcinomas.
- Principal Investigator
  
  ITO Yuko
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Osaka Medical College
Inhibitory study on lymnph node metastasis of mammary cancer by SATB1 and VEGF-C siRNA and decoy vectorsPrincipal Investigator
- Principal Investigator
  
  SHIBTA Masa-aki
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Osaka Health Science University
  Osaka Medical College
Lymphangiogenesis and lymph node-metastasis in the inoculated mouse mammary carcinomas
- Principal Investigator
  
  ITO Yuko
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Osaka Medical College
Inhibition of lymph node metastasis of mammary cancer due to functional loss of lymphangiogenesis factors by siRNA and/or decoy vectorsPrincipal Investigator
- Principal Investigator
  
  SHIBATA Masa-aki
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Osaka Medical College
Study of the anti-cancer treatment that controls the interactions between breast cancer and its micro-environment for inhibition of invasion and metastasis.
- Principal Investigator
  
  MORIAKI Kusakabe
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  Institute for Animal Reproduction
Short interfering RNA vectors against VEGF-C and VEGF-A suppress lymphatic metastasis and lymphatic metastasis of mammary cancer modelPrincipal Investigator
- Principal Investigator
  
  SHIBATA Masa-aki
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Osaka Medical College
Combination cancer gene therapy in endostatin and suicide gene for metastatic murine mammary cancersPrincipal Investigator
- Principal Investigator
  
  SHIBATA Masa-aki
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Osaka Medical College
Intracellular signal pathway of heat-induced apoptosis in human lung cancer cell lines
- Principal Investigator
  
  OTSUKI Yoshinori, 立花秀一
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  Osaka Medical College
Gene therapy using apoptosis-inducer bax and suicide gene for chemically induced rat bladder cancerPrincipal Investigator
- Principal Investigator
  
  SHIBATA Masa-aki
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Osaka Medical College

[Book] 第１章　細胞増殖、「伊東毒性病理学」2013
- Author(s)
  柴田雅朗
- Total Pages
  526
- Publisher
  丸善出版
- Data Source
  KAKENHI-PROJECT-24591924
[Book] Inhibition of tumor growth and metastasis by a combination of anti-VEGF-C and enhanced IL-12 therapy in an immunocompetent mouse mammary cancer model.「Breast Cancer-Current and Alternative Therapeutic Modalities」2011
- Author(s)
  Shibata, M. A., Morimoto, J., Shibata, E., Harada-Shiba, M. and Fujioka, S.
- Publisher
  InTech社
- Data Source
  KAKENHI-PROJECT-21591682
[Journal Article] Antitumor effects of chemically modified miR-143 lipoplexes in a mouse model of pelvic colorectal cancer via myristoylated alanine-rich C kinase substrate downregulation2023
- Author(s)
  Arima Jun、Taniguchi Kohei、Sugito Nobuhiko、Heishima Kazuki、Tokumaru Yoshihisa、Inomata Yosuke、Komura Kazumasa、Tanaka Tomohito、Shibata Masa-Aki、Lee Sang-Woong、Akao Yukihiro
- Journal Title
  
  Molecular Therapy - Nucleic Acids
  
  Volume: 34 Pages: 102079-102079
- DOI
  10.1016/j.omtn.2023.102079
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02992, KAKENHI-PROJECT-23K21471
[Journal Article] Urethane-induced Mammary Carcinogenesis Susceptibility in Transgenic Mice Expressing a Dominant-negative TGF-β Type II Receptor2020
- Author(s)
  SHIBATA MASA-AKI、SHIBATA EIKO、MORIMOTO JUNJI、KONDO YOICHI
- Journal Title
  
  Anticancer Research
  
  Volume: 40 Issue: 5 Pages: 2687-2694
- DOI
  10.21873/anticanres.14239
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08606
[Journal Article] Crude α-Mangostin Suppresses the Development of Atherosclerotic Lesions in Apoe-Deficient Mice by a Possible M2 Macrophage-Mediated Mechanism2019
- Author(s)
  Shibata Masa-Aki、Harada-Shiba Mariko、Shibata Eiko、Tosa Hideki、Matoba Yoshinobu、Hamaoka Hitomi、Iinuma Munekazu、Kondo Yoichi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 20 Issue: 7 Pages: 1722-1722
- DOI
  10.3390/ijms20071722
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08606
[Journal Article] A novel resveratrol tetramer vaticanol C from stem bark acts as an anti-metastatic action in a mouse mammary cancer model2015
- Author(s)
  Shibata, MA, Akao, Y and Iinuma, M
- Journal Title
  
  Alternative and Integrative Medicine
  
  Volume: 4 Issue: 02 Pages: 2-3
- DOI
  10.4172/2327-5162.1000e118
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24591924
[Journal Article] Effects of mangosteen pericarp extracts against mammary cancer2013
- Author(s)
  Shibata MA, Matoba Y, Tosa H and Iinuma M
- Journal Title
  
  Altern Integ Med
  
  Volume: 2 Pages: 8-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591924
[Journal Article] Therapy with siRNA for Vegf-c but not for Vegf-d suppresses wide-spectrum organ metastasis in an immunocompetent xenograft model of metastatic mammary cancer2013
- Author(s)
  Shibata MA, Shibata E, Morimoto J and Harada-Shiba M
- Journal Title
  
  Anticancer Res.
  
  Volume: 33 Pages: 4237-4247
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591924
[Journal Article] テネイシンC抗体とα-マンゴスチンとの複合投与による乳癌転移抑制の試み2013
- Author(s)
  柴田雅朗、日下部守昭、森本純司、柴田映子、斯波真理子、的場吉信、土佐秀樹、飯沼宗和
- Journal Title
  
  乳癌基礎研究
  
  Volume: 22 Pages: 9-14
- Data Source
  KAKENHI-PROJECT-24591924
[Journal Article] スプライシング・バリアントである可溶性VEGF受容体2型のマウス乳癌リンパ節転移に対する抑制効果2012
- Author(s)
  柴田雅朗、J. Ambati,柴田映子、R. JC Albuquerque,森本純司、斯波真理子、藤岡重和、伊藤裕子、大槻勝紀
- Journal Title
  
  リンパ学
  
  Volume: 35巻 Pages: 23-28
- Data Source
  KAKENHI-PROJECT-22591446
[Journal Article] Persistent Median Artery Cadaveric Study and Review of the Literature2011
- Author(s)
  N.EID, Y.ITO, M.A.SHIBATA., Y.OTSUKI
- Journal Title
  
  Clin Anat
  
  Volume: (On line)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591446
[Journal Article] 新規の内因性可溶性VEGF受容体2型は高転移性マウス乳癌のリンパ節転移を抑制する2011
- Author(s)
  柴田雅朗, Ambati Jayakrishna, 柴田映子, Albuquerque Romulo, 森本純司
- Journal Title
  
  乳癌基礎研究
  
  Volume: 20巻 Pages: 22-30
- Data Source
  KAKENHI-PROJECT-21591682
[Journal Article] 新規の内因性可溶性VEGF受容体2型は高転移性マウス乳癌のリンパ節転移を抑制する2011
- Author(s)
  柴田雅朗, 他4名
- Journal Title
  
  乳癌基礎研究
  
  Volume: 20 Pages: 23-30
- Data Source
  KAKENHI-PROJECT-21591682
[Journal Article] Lymphangiogenesis and Axillary Lymph NodeMetastases Correlated with VEGF-C Expression in Two ImmunocompetentMouseMammary CarcinomaModels.2011
- Author(s)
  Yuko Ito, Masa-Aki Shibata,Nabil Eid, JunjiMorimoto and Yoshinori Otsuki
- Journal Title
  
  International Journal of Breast Cancer
  
  Volume: 2011 Pages: 1-10
- DOI
  10.4061/2011/867152
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591446
[Journal Article] VEGF-C, VEGF-DあるいはVEGF-A siRNA発現ベクターを用いた高転移性マウス乳癌モデルに対する癌遺伝子治療2010
- Author(s)
  柴田雅朗, 森本純司, 柴田映子, 大槻勝紀
- Journal Title
  
  リンパ学
  
  Volume: 33巻 Pages: 42-47
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591682
[Journal Article] The endogenous soluble VEGF receptor-2 isoform suppresses lymph node metastasis in a mouse immunocompetent mammary cancer model2010
- Author(s)
  Masa-Aki Shibata, Jayakrishna Ambati, Eiko Shibata, Romulo JC Albuquerque, Junji Morimoto, Yuko Ito, Yoshinori Otsuki
- Journal Title
  
  BMC Medicine
  
  Volume: 8 Pages: 69-81
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591446
[Journal Article] The endogenous soluble VEGF receptor-2 isoform suppresses lymph node metastasis in a mouse immunocompetent mammary cancer model2010
- Author(s)
  Shibata, M. A., Ambati, J., Shibata, E., Albuquerque, R. J., Morimoto, J., Ito, Y. and Otsuki, Y.
- Journal Title
  
  BMC Med
  
  Volume: 8巻
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591682
[Journal Article] The endogenous soluble VEGF receptor-2 isoform suppresses lymph node metastasis in a mouse immunocompetent mammary cancermodel.2010
- Author(s)
  Masa-Aki Shibata, Jayakrishna Ambati, Eiko Shibata, Romulo JC Albuquerque, Junji Morimoto, Yuko Ito,Yoshinori Otsuki
- Journal Title
  
  BMC Medicine
  
  Volume: 8 Pages: 69-81
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591446
[Journal Article] The endogenous soluble VEGF receptor-2 isoform suppresses lymph node metastasis in a mouse immunocompetent mammary cancer model2010
- Author(s)
  Shibata, MA, et al., 他6名
- Journal Title
  
  BMC Medicine
  
  Volume: 8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591682
[Journal Article] リンパ管新生(VEGF-C)に対するsiRNAを用いたマウス乳癌転移の抑制ならびにIL-12遺伝子との複合治療2008
- Author(s)
  柴田雅朗, ほか
- Journal Title
  
  乳癌基礎研究 17
  
  Pages: 49-52
- Data Source
  KAKENHI-PROJECT-19591520
[Journal Article] リンパ管新生(VEGF-C)に対するsiRNAを用いたマウス乳癌転移の抑制ならびにIL-12遺伝子との複合治療2008
- Author(s)
  柴田雅朗、森本純司、赤松香奈子、大槻勝紀
- Journal Title
  
  乳癌基礎研究 17巻
  
  Pages: 49-52
- Data Source
  KAKENHI-PROJECT-19591520
[Journal Article] Combination therapy with short interfering RNA vectors against VEGF-C and VEGF-A suppresses lymph node and lung metastasis in a mouse immunocompetent mammary cancer model2008
- Author(s)
  Shibata, M-A., et al.
- Journal Title
  
  Cancer Gene Therapy 15
  
  Pages: 776-786
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591520
[Journal Article] Combination therapy with short interfering RNA vector against VEGF-C and VEGF-A suppresses lymph node and lung metastasis in a mouse immunocompetent mammary cancer model2008
- Author(s)
  Shibata, M-A., Morimoto, J., Shibata, E. and Otsuki, Y
- Journal Title
  
  Cancer Gene Ther 15
  
  Pages: 776-786
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591520
[Journal Article] 移転性乳癌モデルを用いた実験的癌治療の試み-脈管を標的とした癌遺伝子治療-2007
- Author(s)
  柴田雅朗
- Journal Title
  
  大阪医科大学雑誌 65・3
  
  Pages: 77-78
- Data Source
  KAKENHI-PROJECT-17591360
[Journal Article] 転移性乳癌モデルを用いた実験的乳癌治療の試み-脈管を標的とした癌遺伝子治療-2007
- Author(s)
  柴田雅朗
- Journal Title
  
  大阪医科大学雑誌 65・3
  
  Pages: 77-78
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591360
[Journal Article] Experimental cancer therapy on murine metastatic mammary cancer-cancer gene therapy targeting2006
- Author(s)
  Masa-Aki Shibata
- Journal Title
  
  J.Osaka Med.College 65-3
  
  Pages: 77-78
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591360
[Presentation] マウス乳癌転移モデルにおけるリンパ節での転移前および転移後ニッチのVegfsを標的とするmicroRNA網羅的解析2020
- Author(s)
  柴田雅朗、谷口高平、奥﨑大介、伊藤裕子、白岡千夏、生出林太郎、近藤洋一、
- Organizer
  第36回日本毒性病理学会総会及び学術集会
- Data Source
  KAKENHI-PROJECT-18K08606
[Presentation] 乳癌転移モデルにおけるリンパ節転移前および転移後微小環境のマイクロRNA発現プロファイル2020
- Author(s)
  柴田雅朗、谷口高平、奥﨑大介、伊藤裕子、白岡千夏、生出林太郎、近藤洋一
- Organizer
  第125回日本解剖学会総会全国学術集会
- Data Source
  KAKENHI-PROJECT-18K08606
[Presentation] The biological features of exosomes secreted from highly metastatic mouse mammary carcinomas2019
- Author(s)
  Yuko Ito, Masa-Aki Shibata, Kohei Taniguchi, Yukihiro Akao, Kazuhisa Uchiyama
- Organizer
  第78回日本癌学会総会
- Data Source
  KAKENHI-PROJECT-16K10482
[Presentation] Premetastatic niche formation of the lymph nodes in a mouse model of mammary cancer2019
- Author(s)
  柴田雅朗、伊藤裕子、濱岡仁美、谷口高平
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K08606
[Presentation] マウス乳癌転移におけるリンパ節での転移前ニッチの形成2019
- Author(s)
  柴田雅朗、伊藤裕子、田中義久、二木杉子、濱岡仁美、近藤洋一
- Organizer
  第124回日本解剖学会総会全国学術集会
- Data Source
  KAKENHI-PROJECT-18K08606
[Presentation] マウス乳癌転移モデルにおけるリンパ節の転移前ニッチの形成2019
- Author(s)
  柴田雅朗、伊藤裕子、田中義久、濱岡仁美、近藤洋一
- Organizer
  第35回日本毒性病理学会総会
- Data Source
  KAKENHI-PROJECT-18K08606
[Presentation] マウス乳癌転移モデルにおけるリンパ節の転移前ニッチの形成2019
- Author(s)
  柴田雅朗、伊藤裕子、田中義久、濱岡仁美、近藤洋一
- Organizer
  第35回日本毒性病理学会総会及び学術集会
- Data Source
  KAKENHI-PROJECT-18K08606
[Presentation] マウス乳癌転移モデルにおけるリンパ節の転移前ニッチの形成2019
- Author(s)
  柴田雅朗、伊藤裕子、濱岡仁美、谷口高平
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K08606
[Presentation] マウス乳癌転移におけるリンパ節での転移前ニッチの形成2019
- Author(s)
  柴田雅朗、伊藤裕子、田中義久、二木杉子、濱岡仁美、近藤洋一
- Organizer
  第124回日本解剖学会総会
- Data Source
  KAKENHI-PROJECT-18K08606
[Presentation] 高転移性マウス乳癌が分泌するエクソソームの生物学的特徴2019
- Author(s)
  伊藤裕子、柴田雅朗、谷口高平、ナビル・イード、濱岡仁美、大槻勝紀、近藤洋一
- Organizer
  第１２４回日本解剖学会総会
- Data Source
  KAKENHI-PROJECT-16K10482
[Presentation] マウス乳癌転移モデルにおけるリンパ節の転移前ニッチの形成2018
- Author(s)
  柴田雅朗、伊藤裕子、田中義久、二木杉子、濱岡仁美、近藤洋一
- Organizer
  第27回乳癌基礎研究会
- Data Source
  KAKENHI-PROJECT-18K08606
[Presentation] Mouse mammary carcinomas secrete extracellular vesicles. ―in vitro and in vivo study―2018
- Author(s)
  Yuko Ito, Nabil Eid, Masa-Aki Shibata, Yoshinori Otsuki and Yoichi Kondo
- Organizer
  2nd World Congress on Cancer
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10482
[Presentation] The ultrastructural features of exosomes derived from mouse mammary carcinomas in vitro and in vivo studies2018
- Author(s)
  Yuko Ito, Masa-Aki Shibata, Kohei Taniguchi, Yukihiro Akao
- Organizer
  第７７回日本癌学会総会
- Data Source
  KAKENHI-PROJECT-16K10482
[Presentation] Microvesiclesによる細胞間コミュニケーション2017
- Author(s)
  伊藤裕子, 柴田雅朗, 前村憲太朗, 近藤洋一
- Organizer
  第58回組織細胞化学学会
- Invited
- Data Source
  KAKENHI-PROJECT-16K10482
[Presentation] 高転移性マウス乳癌細胞はprecursor VEGF-Cをautocrineする2016
- Author(s)
  伊藤裕子、ナビル・イード、前村憲太朗、柴田雅朗、大槻勝紀
- Organizer
  第１２１回解剖学会
- Place of Presentation
  ビッグパッレット福島
- Year and Date
  2016-03-28
- Data Source
  KAKENHI-PROJECT-25462003
[Presentation] マンゴスチン果皮抽出物のα-マンゴスチンを模倣した合成α-マンゴスチンドデカン酸ジエステルのマウス乳癌転移抑制2016
- Author(s)
  柴田雅朗、濱岡仁美、伊藤裕子
- Organizer
  第７５回日本癌学会総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-16K10482
[Presentation] マウス乳癌細胞はVEGF-C前駆体を内包したmicrovesiclesを分泌する2015
- Author(s)
  伊藤裕子、柴田雅朗、前村憲太朗、谷口高平、赤尾幸博、大槻勝紀
- Organizer
  第７４回日本癌学会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2015-10-10
- Data Source
  KAKENHI-PROJECT-25462003
[Presentation] テネイシンＣ抗体またはα-マンゴスチンの単独投与ならびにそれらの複合投与によるマウス乳癌転移抑制2014
- Author(s)
  柴田雅朗, 日下部守昭, 柴田映子, 森本純司, 斯波真理子, 飯沼宗和
- Organizer
  第30回日本毒性病理学会総会・学術集会
- Place of Presentation
  あわぎんホール(徳島)
- Data Source
  KAKENHI-PROJECT-24591924
[Presentation] マウス乳癌細胞はprecursor VEGF-C を内包したexosomeを放出する2014
- Author(s)
  伊藤裕子、ナビル・イード、柴田雅朗、赤尾幸博、大槻勝紀
- Organizer
  第119回日本解剖学会総会
- Place of Presentation
  自治医科大学キャンパス
- Data Source
  KAKENHI-PROJECT-25462003
[Presentation] テネイシンＣ抗体およびα-マンゴスチンによるマウス乳癌の転移抑制2013
- Author(s)
  柴田雅朗, 森本純司, 日下部守昭
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜パシフィコ
- Data Source
  KAKENHI-PROJECT-24591924
[Presentation] テネイシンＣ抗体とα-マンゴスチンとの複合投与による乳癌転移抑制の試み2013
- Author(s)
  柴田雅朗、日下部守昭、森本純司ほか５名
- Organizer
  第118回日本解剖学会総会・全国学術総会
- Place of Presentation
  かがわ国際会議場（高松）
- Data Source
  KAKENHI-PROJECT-24591924
[Presentation] テネイシンＣ抗体とα-マンゴスチンとの複合投与によるマウス乳癌転移抑制の試み2013
- Author(s)
  柴田雅朗, 日下部守昭, 森本純司, 柴田映子, 斯波真理子, 的場吉信, 土佐秀樹, 飯沼宗和
- Organizer
  第22回乳癌基礎研究会
- Place of Presentation
  三重大学医学部
- Data Source
  KAKENHI-PROJECT-24591924
[Presentation] マウス乳癌細胞はMicrovesicles(MVs)を放出する2013
- Author(s)
  伊藤裕子、ナビル・イード、柴田雅朗、赤尾幸博、大槻勝紀
- Organizer
  第118回日本解剖学会総会・全国学術集会
- Place of Presentation
  高松
- Data Source
  KAKENHI-PROJECT-22591446
[Presentation] 新規内因性リンパ管新生抑制因子である可溶性VEGF受容体2型のマウス乳癌に対するリンパ節転移抑制作用2011
- Author(s)
  柴田雅朗
- Organizer
  第35回日本リンパ学会総会
- Place of Presentation
  東京
- Year and Date
  2011-06-03
- Data Source
  KAKENHI-PROJECT-21591682
[Presentation] リンパ管新生を標的とした新規内因性可溶性VEGF受容体2型のマウス乳癌リンパ節転移抑制2011
- Author(s)
  柴田雅朗
- Organizer
  第43回日本臨床分子形態学会総会・シンポジウム
- Place of Presentation
  大阪
- Year and Date
  2011-09-09
- Data Source
  KAKENHI-PROJECT-21591682
[Presentation] リンパ管新生を標的とした新規内因性可溶性VEGF受容体2型のマウス乳癌リンパ節転移抑制2011
- Author(s)
  柴田雅朗
- Organizer
  第43回日本臨床分子形態学会総会
- Place of Presentation
  大阪
- Year and Date
  2011-09-09
- Data Source
  KAKENHI-PROJECT-21591682
[Presentation] マウス移植乳癌におけるCEACAM-1の発現とリンパ管新生に対する役割について2011
- Author(s)
  伊藤裕子、柴田雅朗、ナビル・イード、大槻勝紀
- Organizer
  第52回日本組織細胞化学会
- Place of Presentation
  金沢大学医学部キャンパス
- Year and Date
  2011-09-24
- Data Source
  KAKENHI-PROJECT-22591446
[Presentation] 新規内因性リンパ管新生抑制因子である可溶性VEGF受容体2型のマウス乳癌に対するリンパ節転移抑制作用2011
- Author(s)
  柴田雅朗
- Organizer
  第35回日本リンパ学会総会・シンポジウム
- Place of Presentation
  東京
- Year and Date
  2011-06-03
- Data Source
  KAKENHI-PROJECT-21591682
[Presentation] CEACAM1 expression and its effects on lymphangiogenesis in the inoculated mice mammary carcinomas.2011
- Author(s)
  Yuko Ito, Masa-Aki Shibata, Nabil AS Eid, Yoshinori Otsuki
- Organizer
  第116回日本解剖学会・第88回日本生理学会合同総会
- Place of Presentation
  パシフィコ横浜(東日本大震災のためJ.Physiol Sciの誌上開催)
- Year and Date
  2011-03-28
- Data Source
  KAKENHI-PROJECT-22591446
[Presentation] エレクトロポレーションによる実験動物を用いた癌遺伝子治療の基礎2010
- Author(s)
  柴田雅朗
- Organizer
  第33回日本分子生物学会年会・第38回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-21591682
[Presentation] Splicing variantである可溶性VEGF受容体2(sVEGFR-2)遺伝子は高転移性マウス乳癌に対してリンパ節転移ならびに肺転移を抑制する2010
- Author(s)
  柴田雅朗
- Organizer
  第20回乳癌基礎研究会
- Place of Presentation
  宮崎
- Year and Date
  2010-07-17
- Data Source
  KAKENHI-PROJECT-21591682
[Presentation] 血管新生・リンパ管新生を標的とした乳癌治療の基礎研究2010
- Author(s)
  柴田雅朗
- Organizer
  第42回日本臨床分子形態学会総会・学術集会
- Place of Presentation
  静岡
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-21591682
[Presentation] VEGF-C, VEGF-DおよびVEGF-A siRNA発現ベクターを用いた高転移性マウス乳癌モデルに対する癌遺伝子治療2009
- Author(s)
  柴田雅朗(発表確定)
- Organizer
  第33回日本リンパ学会シンポジウム
- Place of Presentation
  大阪医科大学
- Year and Date
  2009-07-17
- Data Source
  KAKENHI-PROJECT-19591520
[Presentation] VEGF-C, VEGF-DおよびVEGF-A siRNA発現ベクターを用いた高転移性マウス乳癌モデルに対する癌遺伝子治療2009
- Author(s)
  柴田雅朗, ほか
- Organizer
  第33回日本リンパ学会
- Place of Presentation
  大阪
- Year and Date
  2009-07-18
- Data Source
  KAKENHI-PROJECT-19591520
[Presentation] Combination therapy with siRNA vectors against VEGF-C and VEGF-A suppresses lymph node and lung metastasis in a mouse cancer model2009
- Author(s)
  柴田雅朗, ほか
- Organizer
  第15回日本遺伝子治療学会
- Place of Presentation
  大阪
- Year and Date
  2009-07-09
- Data Source
  KAKENHI-PROJECT-19591520
[Presentation] VEGF-CないしはVEGF-Aを標的とするsiRNAベクター複合投与によるマウス乳癌モデルでのリンパ節・肺転移の抑制2009
- Author(s)
  柴田雅朗, ほか
- Organizer
  第68回日本癌学会総会
- Place of Presentation
  横浜
- Year and Date
  2009-10-01
- Data Source
  KAKENHI-PROJECT-19591520
[Presentation] マウス移植乳癌におけるリンパ行性転移について2008
- Author(s)
  伊藤裕子、柴田雅朗、大槻勝紀
- Organizer
  第113回日本解剖学会総会
- Place of Presentation
  大分大学キャンパス
- Year and Date
  2008-03-21
- Data Source
  KAKENHI-PROJECT-19591519
[Presentation] Cell invasion into lymphatics is mediated by hyaluronic acid in CD44-expressing mouse mammary carcinoma2008
- Author(s)
  Yuko Ito, Masa-Aki Shibata, Junji Morimoto, Yoshinori Otsuki
- Organizer
  第67回日本癌学会総会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-19591519
[Presentation] マウス移植乳癌におけるリンパ行性転移について2008
- Author(s)
  伊藤裕子、柴田雅朗、大槻勝紀
- Organizer
  第19回リンパ系・免疫系懇話会
- Place of Presentation
  大分大学医学部
- Year and Date
  2008-03-26
- Data Source
  KAKENHI-PROJECT-19591519
[Presentation] CD44陽性乳癌細胞のリンパ管浸潤について2008
- Author(s)
  伊藤裕子、柴田雅朗、大槻勝紀
- Organizer
  第49回日本組織細胞化学会総会
- Place of Presentation
  長崎大学キャンパス
- Year and Date
  2008-10-06
- Data Source
  KAKENHI-PROJECT-19591519
[Presentation] マウス移植乳癌におけるリンパ行性転移について2008
- Author(s)
  伊藤裕子、柴田雅朗、赤松香奈子、阿部英明、大槻勝紀
- Organizer
  第113回解剖学会総会
- Place of Presentation
  大分大学医学部
- Year and Date
  2008-03-28
- Data Source
  KAKENHI-PROJECT-19591519
[Presentation] CD44陽性乳癌細胞のリンパ管浸潤について2008
- Author(s)
  伊藤裕子, 柴田雅朗, 大槻勝紀
- Organizer
  第49回日本組織細胞化学会
- Place of Presentation
  長崎大学キャンパス
- Year and Date
  2008-10-06
- Data Source
  KAKENHI-PROJECT-19591519
[Presentation] マウス移植乳癌におけるリンパ管の再生とリンパ行性転移について2007
- Author(s)
  伊藤裕子、柴田雅朗、大槻勝紀
- Organizer
  第48回日本組織細胞化学会総会
- Place of Presentation
  山梨県民会館
- Year and Date
  2007-09-28
- Data Source
  KAKENHI-PROJECT-19591519
[Presentation] マウス移植乳癌におけるリンパ管の再生とリンパ節への転移について2007
- Author(s)
  伊藤裕子、柴田雅朗、大槻勝紀
- Organizer
  第31回日本リンパ学会総会
- Year and Date
  2007-06-09
- Data Source
  KAKENHI-PROJECT-19591519
[Presentation] マウス移植乳癌におけるリンパ管の再生とリンパ行性転移について2007
- Author(s)
  伊藤裕子、柴田雅朗、大槻勝紀
- Organizer
  第48回日本組織細胞化学会、第39回日本臨床分子形態学会
- Place of Presentation
  甲府市総合市民会館
- Year and Date
  2007-09-29
- Data Source
  KAKENHI-PROJECT-19591519
[Presentation] マウス移植乳癌におけるリンパ管の再生とリンパ節への転移について2007
- Author(s)
  伊藤裕子、柴田雅朗、大槻勝紀
- Organizer
  第31回日本リンパ学会シンポジウム
- Place of Presentation
  艮稜会館
- Year and Date
  2007-06-29
- Data Source
  KAKENHI-PROJECT-19591519
[Presentation] Vascularization of lymphatic vessels and VEGF-C in mouse metastatic mammary carcinoma2007
- Author(s)
  Yuko Ito, Masa-Aki Shibata, Junji Morimoto, Yoshinori Otsuk
- Organizer
  第66回日本癌学会総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2007-10-03
- Data Source
  KAKENHI-PROJECT-19591519
[Presentation] Vascularization of lymphatic vessels and VEGF-C expression in mouse metaStatic mammary carcinoma2007
- Author(s)
  Yuko Ito, Masa-Aki Shibata, Junji Morimoto, Yoshinori Otsuki
- Organizer
  第66回日本癌学会総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2007-10-03
- Data Source
  KAKENHI-PROJECT-19591519
[Presentation] Microvesicles released from two mouse mammary carcinoma cell lines contained premature VEGF-C
- Author(s)
  Ito Y , Nabil Eid , Shibata M, Otsuki Y
- Organizer
  The 120th Annual Meeting of the Japanese Association of Anatomists
- Place of Presentation
  神戸国際国際会議場
- Year and Date
  2015-03-21 – 2015-03-23
- Data Source
  KAKENHI-PROJECT-25462003

1. OTSUKI Yoshinori (50140166)

# of Collaborated Projects: 8 results

# of Collaborated Products: 23 results
2. ITO Yuko (40148432)

# of Collaborated Projects: 8 results

# of Collaborated Products: 40 results
3. MORIMOTO Junji (90145889)

# of Collaborated Projects: 7 results

# of Collaborated Products: 19 results
4. 谷口高平 (70779686)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
5. KUSAKABE Moriaki (60153277)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
6. NABIL Eid (50570165)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
7. KEN TAKESHI Kusakabe (20319536)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. OKADA Toshiya (00169111)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. AKAO Yukihiro (00222505)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
10. TOKITSU Kousuke (60257855)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. HASHIMOTO Takahiko (90340570)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. KUREBAYASHI Junichi (10248255)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. HASHIMOTO Hisashi (80189498)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 武下愛 (50733557)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 立花秀一 (90216987)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 濱岡仁美 (80545608)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
17. 林淳祐 (30740295)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 河村暁文 (50612579)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Shibata Masa-Aki 柴田 雅朗

SHIBATA Masa-aki 柴田 雅朗

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Suppression of mammary cancer metastasis by exosome-associated gene deletion by CRISPR/Cas9 systemPrincipal Investigator

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Combination therapy with inhibition of exosome production and anti-vasculogenesis for suppression of mammary cancer metastasisPrincipal Investigator

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Treatment with tenascin C antibody and/or alpha-mangostin reduces tumor growth and lymph node metastasis in a model of metastatic mammary cancerPrincipal Investigator

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Inhibitory study on lymnph node metastasis of mammary cancer by SATB1 and VEGF-C siRNA and decoy vectorsPrincipal Investigator

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Inhibition of lymph node metastasis of mammary cancer due to functional loss of lymphangiogenesis factors by siRNA and/or decoy vectorsPrincipal Investigator

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Short interfering RNA vectors against VEGF-C and VEGF-A suppress lymphatic metastasis and lymphatic metastasis of mammary cancer modelPrincipal Investigator

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Combination cancer gene therapy in endostatin and suicide gene for metastatic murine mammary cancersPrincipal Investigator

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Shibata Masa-Aki 柴田雅朗

SHIBATA Masa-aki 柴田雅朗

[Book] 第１章　細胞増殖、「伊東毒性病理学」2013