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ZHI Li Huang  黄 志力

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… Alternative Names

黄 志力  ファン ツーリー

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Researcher Number 10321704
Other IDs
Affiliation (based on the past Project Information) *help 2013: 公益財団法人大阪バイオサイエンス研究所, その他部局等, その他
2012: (公財)大阪バイオサイエンス研究所, 分子行動生物学部門, 研究副部長
2011: 公益財団法人大阪バイオサイエンス研究所, 分子行動生物学部門, 研究副部長
2011: 大阪バイオサイエンス研究所, 分子行動生物学部門, 研究副部長
2009 – 2011: Osaka Bioscience Institute, 分子行動生物学部門, 研究副部長 … More
2008: 分子行動生物学部門, 研究員
2008: 財団法人大阪バイオサイエンス研究所, 分子行動生物学部門, 研究員
2007 – 2008: Osaka Bioscience Institute, Department of Molecular Behavioral Biology, Vice head
2007: Osaka Bioscience Institute, 分子行動生物学部門, 研究副部長
2005 – 2006: Osaka Bioscience Institute, Department of Molecular Behavioral Biology, Vice Head, 分子行動生物学部門, 研究副部長
2004: (財)大阪バイオサイエンス研究所, 分子行動生物学部門, 研究員
2001: 財団法人大阪バイオサイエンス研究所, 第2研究部, 日本学術振興会外国人特別研究員 Less
Review Section/Research Field
Principal Investigator
睡眠学 / 睡眠学 / 睡眠科学 / Neuroscience in general
Except Principal Investigator
Neurochemistry/Neuropharmacology / Biological pharmacy / 睡眠学 / Pathological medical chemistry / Fusional basic brain science / Nerve anatomy/Neuropathology / Neuroscience in general
Keywords
Principal Investigator
Adenosine / Sleep / Wakefulness / A2A receptor / A1 receptor / Knockout mice / Caffeine / Hiatamine H1 receptor / wakefulness / sleep … More / 睡眠 / アデノシン / Gene-manipulated mice / Nucleus accumbens / A_<2A> receptor / A_1 receptor / 覚醒 / 遺伝子欠損マウス / 側座核 / カフェイン / A_<2A>受容体 / A_1受容体 / DARPP-32 phosphorylation / knockout mice / Histamine H_1 receptor / adenosine / caffeine / A2A Receptor / Al receptor / nucleus accumbens / locomotor activity / dopamine D2 receptor / caudate-putamen / アデノ随伴ウイルス / アデノ随伴ウィルス / ラット / マウス / 遺伝子操作 … More
Except Principal Investigator
睡眠 / GABA / TMN / Histamine / Gene knockout mice / Wakefulness / 覚醒 / カフェイン / プロスタグランジンD合成酵素 / プロスタグランジンD_2 / humoral regulation / neural network / sleep substances / leep-wake cycle / 液性調節 / 神経回路 / 睡眠物質 / 睡眠覚醒 / glial cell / sleep deprivation / sleep / forced wakefulness / リバウンド / グリア細胞 / 断眠 / 強制覚醒 / Caffeine / A_<2A> receptor / Brief awakening / A2A receptor / Brief awakeming / アデノシンA_<2A>受容体 / ガンマアミノ酪酸 / 結節乳頭核 / ヒスタミン / 遺伝子欠損マウス / 中途覚醒 / obesity / diabetes mellitus / atherosclerosis / sleep disorders / animal model for human disease / gene-manipulated mice / prostaglandin D_2 / prostaglandin D synthase / アレルギー / 肥満 / 糖尿病 / 動脈硬化 / 睡眠障害 / ヒト疾患モデル動物 / 遺伝子操作マウス / SOX5 / 神経 / Sox5 / loxPシステム / Cre / 受容体 / アデノ随伴ウィルス / 側坐核 / 局所的RNAi干渉法 / Cre/loxPシステム / ラット / マウス / 局所的RNA干渉 / 神経回路網 / リポカリン / VLPO / A_<2A>体受容体 / A_<2A>受容体 / アデノシン / 嗅結節 / アデノシンA_2A 受容体 / 脂質 / 薬理学 / 脳神経疾患 Less
  • Research Projects

    (13 results)
  • Research Products

    (140 results)
  • Co-Researchers

    (25 People)
  •  ドーパミンD2受容体による覚醒調節分子機構Principal Investigator

    • Principal Investigator
      黄 志力
    • Project Period (FY)
      2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      睡眠科学
    • Research Institution
      公益財団法人大阪バイオサイエンス研究所
  •  Molecular mechanisms of the sleep control by neurons activated during sleep

    • Principal Investigator
      URADE Yoshihiro
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Fusional basic brain science
    • Research Institution
      公益財団法人大阪バイオサイエンス研究所
      Osaka Bioscience Institute
  •  Developing focal RNA interference for the identification of neural entry points for sleep-promoting adenosine

    • Principal Investigator
      LAZARUS Michael
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Nerve anatomy/Neuropathology
    • Research Institution
      公益財団法人大阪バイオサイエンス研究所
      Osaka Bioscience Institute
  •  Sleep-wake regulation by adenosinePrincipal Investigator

    • Principal Investigator
      HUANG Zhi-li
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neuroscience in general
    • Research Institution
      公益財団法人大阪バイオサイエンス研究所
      Osaka Bioscience Institute
  •  Role of adenosine A_2A receptor in olfactory nuclei in sleep-wake regulation

    • Principal Investigator
      WEI Min Qu
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neuroscience in general
    • Research Institution
      Osaka Bioscience Institute
  •  Lipocalin-type Prostaglandin D synthase; transporter and scavenger for Prostaglandin D2

    • Principal Investigator
      ARITAKE Kosuke
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Osaka Bioscience Institute
  •  Crosstalk of signal transduction in sleep-wake regulation

    • Principal Investigator
      HAYASHI Osamu
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Osaka Bioscience Institute
  •  Roles of adenosine A2A receptors in sleep-wake regulationPrincipal Investigator

    • Principal Investigator
      HUANG Zhi Li
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      睡眠学
    • Research Institution
      Osaka Bioscience Institute
  •  プロスタグランジンD_2産生調節による外傷性大脳皮質損傷の拡大防止と修復促進

    • Principal Investigator
      ARITAKE Kosuke
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Biological pharmacy
    • Research Institution
      Osaka Bioscience Institute
  •  Change in gene expression in glial cells during sleep deprivation

    • Principal Investigator
      NAGATA Nanae
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      睡眠学
    • Research Institution
      Osaka Bioscience Institute
  •  Molecular mechanism of wakefulness regulation

    • Principal Investigator
      HAYAISHI Osamu
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Osaka Bioscience Institute
  •  Sleep research by gene-manipulated adenosine receptor knockout micePrincipal Investigator

    • Principal Investigator
      HUANG Zhi-Li
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      睡眠学
    • Research Institution
      Osaka Bioscience Institute
  •  Molecular mechanisms of diseases generated by our life style and for their association with sleep disorders

    • Principal Investigator
      EGUCHI Naomi
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Osaka Bioscience Institute

All 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004

All Journal Article Presentation Patent

  • [Journal Article] Prostaglandin D2 is crucial for seizure suppression and postictal sleep2014

    • Author(s)
      Kaushik MK, Aritake K, Kamauchi S, Hayaishi O, Huang ZL, Lazarus M, Urade Y
    • Journal Title

      Experimental Neurology

      Volume: 253 Pages: 82-90

    • DOI

      10.1016/j.expneurol.2013.12.002

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24300129, KAKENHI-PROJECT-25515007, KAKENHI-PROJECT-25670047
  • [Journal Article] Role of the basal ganglia in the control of sleep and wakefulness2013

    • Author(s)
      Lazarus M, Chen JF, Urade Y, and Huang ZL*
    • Journal Title

      Curr Opin Neurobiol

      Volume: 23 Pages: 780-785

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25515007
  • [Journal Article] Role of the basal ganglia in the control of sleep and wakefulness2013

    • Author(s)
      Lazarus, M.; Chen, J. F.; Urade, Y.; Huang, Z. L.
    • Journal Title

      Curr Opin Neurobiol

      Volume: 23 Issue: 5 Pages: 780-785

    • DOI

      10.1016/j.conb.2013.02.001

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22300133, KAKENHI-PROJECT-24300129
  • [Journal Article] Acute administration of fluoxetine normalizes rapid eye movement sleep abnormality but not depressive behaviors in olfactory bulbectomized rats2012

    • Author(s)
      Wang YQ, Tu ZC, Xu XY, Li R, Qu WM, Urade Y, Huang ZL.
    • Journal Title

      J. Neurochem

      Volume: 120 Issue: 2 Pages: 314-324

    • DOI

      10.1111/j.1471-4159.2011.07558.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21380081, KAKENHI-PROJECT-21500313
  • [Journal Article] How do the basal ganglia regulate sleep-wake behavior?2012

    • Author(s)
      Lazarus, M.; Huang, Z. L.; Lu, J.; Urade, Y.; Chen, J. F.
    • Journal Title

      Trends Neurosci

      Volume: 35(12) Pages: 723-32

    • Data Source
      KAKENHI-PROJECT-22300133
  • [Journal Article] Crocin promotes non-rapid eye movement sleep in mice2012

    • Author(s)
      Masaki M, Aritake K, Tanaka H, Shoyama Y, Huang ZL, Urade Y.
    • Journal Title

      Mol Nutr Food Res

      Volume: 56(2) Issue: 2 Pages: 304-308

    • DOI

      10.1002/mnfr.201100181

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21500313
  • [Journal Article] Effects of synthetic cannabinoids on electroencephalogram power spectra in rats2012

    • Author(s)
      Uchiyama N, Kikura-Hanajiri R, Matsumoto N, Huang ZL, Goda Y, Urade Y.
    • Journal Title

      Forensic Sci Int

      Volume: 215(1-3) Issue: 1-3 Pages: 179-183

    • DOI

      10.1016/j.forsciint.2011.05.005

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21500313, KAKENHI-PROJECT-23390183
  • [Journal Article] The role of adenosine in the regulation of sleep2011

    • Author(s)
      Huang ZL, Urade Y and Hayaishi O
    • Journal Title

      Curr Top Med Chem

      Volume: 11(8) Pages: 1047-57

    • URL

      http://www.ncbi.nlm.nih.gov/pubmed/21401496

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21500313
  • [Journal Article] The role of adenosine in the regulation of sleep2011

    • Author(s)
      Huang, Z. L.; Urade, Y.; Hayaishi, O.
    • Journal Title

      Curr Top Med Chem

      Volume: 11 (8) Pages: 1047-57

    • URL

      http://www.ncbi.nlm.nih.gov/pubmed/21401496.

    • Data Source
      KAKENHI-PROJECT-22300133
  • [Journal Article] The role of adenosine in the regulation of sleep2011

    • Author(s)
      Huang ZL, Urade Y, Hayaishi O
    • Journal Title

      Curr Top Med Chem

      Volume: 11 Pages: 1047-1057

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21500313
  • [Journal Article] Magnolol, a major bioactive constituent of the bark of Magnolia officinalis, exerts anti-epileptic effects via GABA-benzodiazepine receptor complex in mice2011

    • Author(s)
      Chen CR, Tan R, Qu WM, Wu Z, Wang Y, Urade Y, Huang ZL.
    • Journal Title

      Br J Pharmacol

      Volume: 164(5) Issue: 5 Pages: 1534-46

    • DOI

      10.1111/j.1476-5381.2011.01456.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21500313
  • [Journal Article] Arousal effect of caffeine depends on adenosine A_<2A> receptors in the shell of the nucleus accumbens2011

    • Author(s)
      Lazarus M, Shen HY, Cherasse Y, Qu WM, Huang ZL, Bass C, Winsky-Sommerer R, Semba K, Fredholm B, Boison D, Hayaishi O, Urade Y, Chen JF.
    • Journal Title

      Journal of Neuroscience

      Volume: 31巻 Issue: 27 Pages: 10067-10075

    • DOI

      10.1523/jneurosci.6730-10.2011

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21300133, KAKENHI-PROJECT-21380081, KAKENHI-PROJECT-21500313
  • [Journal Article] Selection of optimal epoch duration in assessment of rodent sleep-wake profiles2011

    • Author(s)
      Yan MM, Xu XH, Huang ZL, Yao MH, Urade Y, Qu WM.
    • Journal Title

      Sleep Biol Rhythm

      Volume: 9 Issue: 1 Pages: 46-55

    • DOI

      10.1111/j.1479-8425.2010.00484.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21500313
  • [Journal Article] Key roles of the histaminergic system in sleep-wake regulation2011

    • Author(s)
      Huang ZL, Urade Y and Hayaishi
    • Journal Title

      Sleep Biol Rhythm

      Volume: 9 Pages: 34-37

    • DOI

      10.1111/j.1479-8425.2010.00471.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21500313
  • [Journal Article] Arousal effect of caffeine depends on adenosine A_<2A>receptors in the shell of the nucleus accumbens.2011

    • Author(s)
      Lazarus M, Shen HY, Cherasse Y, Qu WM, Huang ZL, et al.
    • Journal Title

      J Neurosci

      Volume: 31 In press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21500313
  • [Journal Article] Essential role of dopamine D_2 receptor in the maintenance of wakefulness, but not in homeostatic regulation of sleep, in mice2010

    • Author(s)
      Qu WM, Xu XH, Yan MM, Wang YQ, Urade Y, Huang ZL.
    • Journal Title

      J Neurosci

      Volume: 30(12) Issue: 12 Pages: 4382-4389

    • DOI

      10.1523/jneurosci.4936-09.2010

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21500313
  • [Journal Article] 1/D2 receptor-targeting L-stepholidine, an active ingredient of the Chinese herb Stephonia, induces non-rapid eye movement sleep in mice2009

    • Author(s)
      Qiu MH, Qu WM, Xu XH, Yan MM, Urade Y, Huang ZL
    • Journal Title

      Pharmacol Biochem Behav 94

      Pages: 16-23

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21500313
  • [Journal Article] Drug delivery through a chronically implanted stomach catheter improves efficiency of evaluating wake-promoting components2008

    • Author(s)
      Qu WM, Huang ZL, Matsumoto N, Xu XH, Urade Y
    • Journal Title

      J Neurosci Methods 175(1)

      Pages: 58-63

    • Data Source
      KAKENHI-PROJECT-19500283
  • [Journal Article] Gene expression in the rat brain during prostaglandin D2-and adenosinergically-induced sleep2008

    • Author(s)
      Terao A, Huang ZL, Wisorl JP, Mochizuki T, Gerashchenko D, Urade Y, Kilduff, TS
    • Journal Title

      J Neurochem 105

      Pages: 1480-1490

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18603011
  • [Journal Article] Gene expression in the rat brain during prostaglandin D_2-and adenosinergically-induced sleep2008

    • Author(s)
      Terao A,Huang ZL,Wisorl JP,Mochizuki T,Gerashchenko D,Urade Y, and Kilduff TS
    • Journal Title

      J Neurochem 105

      Pages: 1480-1490

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18603011
  • [Journal Article] Dopaminergic D1 and D2 receptors are essential for the arousal effect of modafinil2008

    • Author(s)
      Qu WM, Huang ZL, Xu XH, Matsumoto N, Urade Y
    • Journal Title

      J Neurosci 28(34)

      Pages: 8462-8469

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19500283
  • [Journal Article] Gene expression in the rat brain during prostaglandin D2- and adenosinergically-induced sleep2008

    • Author(s)
      Terao A, Huang ZL, Wisorl JP, Mochizuki T, Gerashchenko D, Urade Y, Kilduff TS.
    • Journal Title

      J Neurochem 105

      Pages: 1480-1490

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18603011
  • [Journal Article] Prostaglandins and adenosine in the regulation of sleep and wakefulness2007

    • Author(s)
      Huang Z L, Urade Y, Hayaishi O.
    • Journal Title

      Curr. Opin. Pharmacol. 7

      Pages: 33-38

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18300129
  • [Journal Article] Prostaglandins and adenosine in the regulation of sleep and wakefulness2007

    • Author(s)
      Huang ZL, Urade Y, Hayaishi O.
    • Journal Title

      Curr. Opin. Pharmacol. 7

      Pages: 33-38

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18603011
  • [Journal Article] Prostaglandins and adenosine in the regulation of sleep and wakefulness2007

    • Author(s)
      Huang ZL,Urade Y and Hayaishi O.
    • Journal Title

      Curr. Opin. Pharmacol. 7

      Pages: 33-38

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18300129
  • [Journal Article] Lipocalin-type PGD synthase is a major amyloid β-chaperone in human cerebrospinal fluid.2007

    • Author(s)
      Kanekiyo T, Ban T, Aritake K., Huang Z-L, Qu W-M, Okazaki I, Mohri I, Murayama S, Ozono K, Taniike M, Goto Y, Urade Y.
    • Journal Title

      Proc Natl Acad Sci USA 104(15)

      Pages: 6412-6417

    • Data Source
      KAKENHI-PROJECT-18603011
  • [Journal Article] Lipocalin-type PGD synthase is a major amyloid β-chaperone in human cerebrospinal fluid2007

    • Author(s)
      Kanekiyo T, Aritake S, Yamaguchi K, Huang ZL, QuWM, Ozono K, Taniike M, Goto Y, Urade Y
    • Journal Title

      Proc Natl Acad Sci USA 104(15)

      Pages: 6412-6417

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19500283
  • [Journal Article] Lipocalin-type PGD synthase is a major amyloid β-chaperone in human cerebrospinal fluid2007

    • Author(s)
      Kanekiyo T, Aritake S, Yamaguchi K, Huang ZL, Qu WM, Ozono K, Taniike M, Goto Y, Urade Y.
    • Journal Title

      Proc Natl Acad Sci USA 104

      Pages: 6412-6417

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18603011
  • [Journal Article] Modafinil exerts a dose-dependent antiepileptic effect mediated by adrenergic a1 and histaminergic H1 receptors in mice2007

    • Author(s)
      Chen CR, QuWM, Qiu MH, Xu XH, Yao MH, Urade Y, Huang ZL
    • Journal Title

      Neuropharmacology 53(4)

      Pages: 534-541

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19500283
  • [Journal Article] Deep brain stimulation of the posterior hypothalamus activates the histaminergic system to exert antiepileptic effect in rat pentylentetrazol model2007

    • Author(s)
      Namiko Nishida;Huang ZL,Nobuhiro Mikuni, et. al.
    • Journal Title

      Exp Neurol 205

      Pages: 132-144

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18603011
  • [Journal Article] Lipocalin-type prostaglandin D synthase/beta-trace is a major amyloid beta-chaperone in human cerebrospinal fluid2007

    • Author(s)
      Kanekiyo T, Ban T, Aritake K, Huang ZL, Qu WM, Okazaki I, Mohri I, Murayama S, Ozono K, Taniike M, Goto Y, Urade Y
    • Journal Title

      Proc Natl Acad Sci U S A 104(15)

      Pages: 6412-7

    • Data Source
      KAKENHI-PROJECT-19590094
  • [Journal Article] Adenosine A_<2A> receptors in ventral striatum, hypothalamus and nociceptive circuitry. Implications for drug addiction, sleep and pain2007

    • Author(s)
      Ferre S,Diamond I,Godlberg SR,Yao L,Hourani SMO,Huang ZL,Urade Y and Kitchen,I
    • Journal Title

      Prog Neurobiol 83

      Pages: 332-347

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18603011
  • [Journal Article] Lipocalin-type PGD synthase is a major amyloid β-chaperone in human cerebrospfinal fluid2007

    • Author(s)
      Kanekiyo T, Aritake S, Yamaguchi K, Huang ZL, Qu WM, Ozono K, Taniike M, Goto Y, Urade Y.
    • Journal Title

      Proc Natl Acad Sci USA. 104(15)

      Pages: 6412-6417

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19500283
  • [Journal Article] Prostaglandins and adenosine in the regulation of sleep and wakefulness2007

    • Author(s)
      Huang ZL, Urade Y and Hayaishi O.
    • Journal Title

      Curr.Opin.Pharmacol. 7

      Pages: 33-38

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18300129
  • [Journal Article] Prostaglandins and adenosine in the regulation of sleep and wakefulness2007

    • Author(s)
      Huang ZL,Urade Y and Hayaishi O.
    • Journal Title

      Curr Opin Pharmacol 7(1)

      Pages: 33-38

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18603011
  • [Journal Article] Adenosine A2A receptors in ventral striatum, hypothalamus and nociceptive circuitry. Implications for drug addication, sleep and pain2007

    • Author(s)
      Ferre S, Diamond I, Godlberg SR, Yao L, Hourani SMO, Huang ZL, Urade Y, Kitchen I.
    • Journal Title

      Prog Neurobiol 83

      Pages: 332-347

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18603011
  • [Journal Article] Prostaglandins and adenosine in the regulation of sleep and wakefulness2007

    • Author(s)
      Huang ZL, Uade Y, Hayaishi O.
    • Journal Title

      Curr Opin Pharmacol 7

      Pages: 33-38

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18603011
  • [Journal Article] Lipocalin-type PGD synthase is a major amyloid β-chaperone in human cerebrospinal fluid2007

    • Author(s)
      Kanekiyo T,Aritake S,Yamaguchi K,Huang ZL,Qu WM,Ozono K,Taniike M,Goto Y,Urade Y.
    • Journal Title

      Proc Natl Acad Sci USA 104(15)

      Pages: 6412-6417

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18603011
  • [Journal Article] Lipocalin-type PGD Synthase is a major amyloid β-chaperone in human cerebrospinal fluid2007

    • Author(s)
      Kanekiyo T, Aritake S, Yamaguchi K, Huang ZL, Qu WM, Ozono K, Taniike M, Goto Y, Urade Y.
    • Journal Title

      Proc Natl Acad Sci USA 104(15)

      Pages: 6412-6417

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18603011
  • [Journal Article] Deep brain stimulation of the posterior hypothalamus activates the histaminergic system to exert andtiepileptic effect in rat pentylentetrazol model2007

    • Author(s)
      Nishida N, Huang ZL, Mikuni N, Miura Y, Urade Y, Hashimoto N.
    • Journal Title

      Exp Neurol 205(1)

      Pages: 132-144

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18603011
  • [Journal Article] Deep brain stimulation of the posterior hypothalamus activates the histaminergic system to exert antiepileptic effect in rat pentylentetrazol model.2007

    • Author(s)
      Nishida N, Huang ZL, Mikuni N, et al.
    • Journal Title

      Exp Neurol (in press)

    • Data Source
      KAKENHI-PROJECT-18603011
  • [Journal Article] Prostaglandins and adenosine in the regulation of sleep and wakefulness2007

    • Author(s)
      Huang ZL, Urada Y, Hayaishi O.
    • Journal Title

      Curr Opin Pharmacol 7(1)

      Pages: 33-38

    • Data Source
      KAKENHI-PROJECT-18300129
  • [Journal Article] Modafinil exerts a dose-dependent antiepileptic effect mediated by adrenergic al and histaminergic H1 receptors in mice2007

    • Author(s)
      Chen CR, Qu WM, Qiu MH, Xu XH, Yao MH, Urade Y, Huang ZL
    • Journal Title

      Neuropharmacology 53(4)

      Pages: 534-541

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19500283
  • [Journal Article] Prostaglandins and adenosine in the regulation of sleep and wakefulness2007

    • Author(s)
      Huang ZL, Urade Y, Hayaishi O.
    • Journal Title

      Curr Opin Pharmacol 7(1)

      Pages: 33-38

    • Data Source
      KAKENHI-PROJECT-18603011
  • [Journal Article] Lipocalin-type prostaglandin D synthase produces prostaglandin D_2 involved in regulation of physiological sleep2006

    • Author(s)
      Qu WM,Huang ZL,Xu XH,Aritake K,Eguchi N,Nambu F,Narumiya S,Urade Y and Hayaishi O.
    • Journal Title

      Proc Natl Acad Sci USA 103(47)

      Pages: 17949-17954

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18300129
  • [Journal Article] Alterations of sleep-wake behavioral characterisitcs and lack of arousal response to H_3 receptor antagonist in histamine H_1 receptor knockout mice2006

    • Author(s)
      Huang ZL, Mochizuki T, Qu WM, Hong ZY, Watanabe T, Urade Y, Hayaishi O.
    • Journal Title

      Proc Natl Acad Sci USA 103(12)

      Pages: 4687-4692

    • Data Source
      KAKENHI-PROJECT-18300129
  • [Journal Article] Fasting-induced reduction in locomotor activity and reduced response of orexin neurons in carnitine-deficient mice.2006

    • Author(s)
      Yoshida G, Li MX, Horiuchi M, Nakagawa S, Sakata M, Kuchiiwa S, Kuchiiwa T, Jalil MA, Begum L, Lu YB, Iijima M, Hanada T, Nakazato M, Huang ZL, Eguchi N, Kobayashi K, Saheki T
    • Journal Title

      Neurosci Res 55(1)

      Pages: 78-86

    • NAID

      10020616692

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16614014
  • [Journal Article] Fasting-induced reduction in locomotor activity and reduced response of orexin neurons in camitine-deficient mice2006

    • Author(s)
      Yoshida G,Li MX,Horiuchi M,Nakagawa S,Sakata M,Kuchiiwa S,Kuchiiwa T,Jalil MA,Begum L,Lu YB,Iijima M,Hanada T,Nakazato M,Huang ZL, et. al.
    • Journal Title

      Neurosci Res 55(1)

      Pages: 78-86

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18603011
  • [Journal Article] Alterations of sleep-wake behavioral characteristics and lack of arousal response to H_3 receptor antagonist in histamine H_1 receptor knockout mice2006

    • Author(s)
      Huang ZL, Mochizuki T, Qu WM.Hong ZY, Watanabe T, Urade Y, Hayaishi O.
    • Journal Title

      Proc Natl Acad Sci USA 103(12)

      Pages: 4687-4692

    • Data Source
      KAKENHI-PROJECT-16614014
  • [Journal Article] Altered sleep-wake characteristics and lack of arousal response to H3 receptor antagonist in histamine H1 receptor knockout mice2006

    • Author(s)
      Huang Z L, Mochizuki T, Qu WM, Hong ZY, Watanabe T, Urade Y, Hayaishi O.
    • Journal Title

      Proc Natl Acad Sci USA 103(12)

      Pages: 4687-4692

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18300129
  • [Journal Article] Fasting-induced reduction in locomotor activity and reduced response of orexin neurons in carnitine-deficient mice2006

    • Author(s)
      Yoshida G, Li MX, Horiuchi M, Nakagawa S, Sakata M, Kuchiiwa S, Kuchiiwa T, Jalil MA, Begum L, Lu YB, Iijima M, Hanada T, Nakazato M, Huang ZL, Eguchi N, Kobayashi K, Saheki T.
    • Journal Title

      Neurosci Res (In press)

    • NAID

      10020616692

    • Data Source
      KAKENHI-PROJECT-16614014
  • [Journal Article] Alterations of sleep-wake behavioral characteristics and lack of arousal response to H_3 receptor antagonist in histamine H_1 receptor knockout mice2006

    • Author(s)
      Huang ZL,Mochizuki T,Qu WM,Hong ZY,Watanabe T,Urade Y and Hayaishi O.
    • Journal Title

      Proc Natl Acad Sci USA 103(12)

      Pages: 4687-4692

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18603011
  • [Journal Article] Altered sleep-wake characteristics and lack of arousal response to H_3 receptor antagonist in histamine H_1 receptor knockout mice.2006

    • Author(s)
      Huang ZL, Mochizuki T, Qu WM, Hong ZY, Watanabe T, Urade Y, Hayaishi O
    • Journal Title

      Proc Natl Acad Sci USA 103(12)

      Pages: 4687-4692

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16614014
  • [Journal Article] Lipocalin-type prostaglandin D synthase produces prostaglandin D_2 involved in regulation of physiological sleep.2006

    • Author(s)
      Qu WM, Huang ZL, Xu XH, Aritake K, Eguchi N, Nambu F, Narumiya S, Urade Y, Hayaishi O.
    • Journal Title

      Proc Natl Acad Sci USA 103(47)

      Pages: 17949-17954

    • Data Source
      KAKENHI-PROJECT-18603011
  • [Journal Article] Altered sleep-wake characteristics and lack of arousal response to H_3 receptor antagonist in histamine H_1 receptor knockout mice.2006

    • Author(s)
      Huang, Z.-L., et al.
    • Journal Title

      Proc. Natl. Acad. Sci. USA 103

      Pages: 4687-4692

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16300123
  • [Journal Article] Alterations of sleep-wake behavioral characteristics and lack of arousal response to H_3 receptor antagonist in histamine H_1 receptor knockout mice2006

    • Author(s)
      Huang ZL, Mochizuki T, Qu WM, Hong ZY, Watanabe T, Urade Y, Hayaishi O.
    • Journal Title

      Proc Natl Acad Sci USA 103(12)

      Pages: 4687-4692

    • Data Source
      KAKENHI-PROJECT-18603011
  • [Journal Article] Lipocalin-type prostaglandin D synthase produces prostaglandin D2 involved in regulation of physiological sleep2006

    • Author(s)
      Qu WM, Huang Z L, Xu XH, Aritake K, Eguchi N, Nambu F, Narumiya S, Urade Y, Hayaishi O.
    • Journal Title

      Proc Natl Acad Sci USA 103(47)

      Pages: 17949-17954

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18300129
  • [Journal Article] Lipocalin-type prostaglandin D synthase produces prostaglandin D_2 involved in regulation of physiological sleep2006

    • Author(s)
      Qu WM,Huang ZL,Xu XH,Aritake K,Eguchi O,Nambu F,Narumiya S,Urade Y and Hayaishi O.
    • Journal Title

      Proc Natl Acad Sci USA 103(47)

      Pages: 17949-17954

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18603011
  • [Journal Article] Lipocalin-type prostaglandin D synthase produces prostaglandin D_2 involved in regulation of physiological sleep2006

    • Author(s)
      Qu WM, Huang ZL, Xu XH, Aritake K, Eguchi N, Nambu F, Narumiya S, Urade Y, Hayashi O.
    • Journal Title

      Proc Natl Acdd Sci USA 103(47)

      Pages: 17949-17954

    • Data Source
      KAKENHI-PROJECT-18300129
  • [Journal Article] Altered sleep-wake characteristics and lack of arousal response to H_3 raceptor antagonist in histamine H_1 receptor knockout mice2006

    • Author(s)
      Huang ZL, et al.
    • Journal Title

      Proc Natl Acad Sci USA 103(2)

      Pages: 4687-4692

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16614014
  • [Journal Article] Altered sleep-wake characteristics and lack of arousal response to H3 receptor antagonist in histamine h1 receptor knockout mice2006

    • Author(s)
      Huang ZL, Mochizuki T, Qu WM, Hong ZY, Watanabe T, Urade Y, Hayaishi O.
    • Journal Title

      Proc Natl Aci USA 103(12)

      Pages: 4687-4692

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18603011
  • [Journal Article] and Hayaishi O. Lipocalin-type prostaglandin D synthase produces prostaglandin D2 involved in regulation of physiological sleep2006

    • Author(s)
      Qu WM, Huang ZL, Xu XH, Aritake K, Eguchi N, Nambu F, Narumiya S, Urade Y
    • Journal Title

      Proc Natl Acad Sci USA 103(47)

      Pages: 17949-17954

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18603011
  • [Journal Article] Fasting-induced reduction in locomotro activity and reduced response of orexin neurons in carnitine-deficient mice2006

    • Author(s)
      Yoshida G, Li MX, Horiuchi M, Nakagawa S, Sakata M, Kuchiiwa S, Kuchiiwa T, Jalil MA, Begum L, Lu YB, Iijima M, Hanada T, Nakazato M, Huang ZL, Etal.
    • Journal Title

      Neurosci Res 55(1)

      Pages: 78-86

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18603011
  • [Journal Article] Altered sleep-wake characteristics and lack of arousal response to H_3 receptor antagonist in histamine H_1 receptor knockout mice2006

    • Author(s)
      Huang, Z.-L., Mochizuki, T., Qu, W.-M., Hong, Z.-Y., Watanabe, T., Urade, Y., Hayaishi, O.
    • Journal Title

      Proc.Natl.Acad.Sci.USA 103

      Pages: 4687-4692

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16300123
  • [Journal Article] Altered sleep-wake characteristics and lack of arousal response to H_3 receptor antagonist in histamine H_1 receptor knockout mice.2006

    • Author(s)
      Huang, Z.-L., Mochizuki, T., Qu, W.-M., Hong, Z.-Y., Watanabe, T., Urade, Y., Hayaishi, O.
    • Journal Title

      Proc.Natl.Acad.Sci.USA 103(12)

      Pages: 4687-4692

    • Data Source
      KAKENHI-PROJECT-16300123
  • [Journal Article] Altered sleep-wake characteristics and lack of arousal response to H3 receptor antagonist in histamine H1 receptor knockout mice2006

    • Author(s)
      Huang ZL,Mochizuki T,Qu WM,Hong ZY,Watanabe T,Urade Y and Hayaishi O.
    • Journal Title

      Proc Natl Acad Sci USA 103(12)

      Pages: 4687-4692

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18300129
  • [Journal Article] Fasting-induced reduction in locomotor activity and reduced response of orexin neurons in carnitine-deficient mice2006

    • Author(s)
      Yoshida G, Li MX, Horiuchi M, Nakagawa S, Sakata M, Kuchiiwa S, Kuchiiwa T, Jalil MA, Begum L, Lu YB, Iijima M, Hanada T, Nakazato M, Huang ZL, et al.
    • Journal Title

      Neurosci Res 55(1)

      Pages: 78-86

    • Data Source
      KAKENHI-PROJECT-18603011
  • [Journal Article] Adenosine A2A, but not A1, receptors mediate the arousal effect of caffeine.2005

    • Author(s)
      Huang ZL, Qu WM, Eguchi, N, Chen JF, Schwarzschild MA, Fredholm BB, Urade Y, Hayaishi O
    • Journal Title

      Nat Neurosci 8(7)

      Pages: 858-859

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16614014
  • [Journal Article] Roles of prostaglandin in the sleep-wake regulation. (Japanese)2005

    • Author(s)
      Urade Y, Huang ZL, Eguchi N
    • Journal Title

      Hormone and Clinics 53

      Pages: 573-581

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16614014
  • [Journal Article] Adenosine A_<2A>, but not A_1, receptors mediate the arousal effect of caffeine2005

    • Author(s)
      Huang ZL, Qu WM, Eguchi N, Chen JF, Schwarzschild MA, Fredholm BB, Urade Y, Hayaishi O.
    • Journal Title

      Nat Neurosci 8(7)

      Pages: 858-859

    • Data Source
      KAKENHI-PROJECT-16614014
  • [Journal Article] An adenosine A_<2A> receptor agonist induces sleep by increasing GABA release in the tuberomammillary nucleus to inhibit histaminergic in rats.2005

    • Author(s)
      Hong ZY, Huang ZL, Qu WM, Eguchi N, Urade Y, Hayaishi O.
    • Journal Title

      J Neurochem 92

      Pages: 1542-1549

    • Data Source
      KAKENHI-PROJECT-16614014
  • [Journal Article] Orexin A promotes histamine, but not noradrenaline or serotonin release, in the frontal cortex of mice.2005

    • Author(s)
      Hong ZY, Huang ZL, Qu WM, Eguchi N
    • Journal Title

      Acta Pharmacol Sin 26(2)

      Pages: 155-159

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16614014
  • [Journal Article] Adenosine A_<2A>, but not A_1, receptors mediate the arousal effect of caffeine.2005

    • Author(s)
      Huang, Z.-L., et al.
    • Journal Title

      Nat. Neurosci. 8

      Pages: 858-859

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16300123
  • [Journal Article] Roles of prostaglandin in the sleep-wake regulation2005

    • Author(s)
      Urade Y, Huang ZL, Eguchi N
    • Journal Title

      Hormone and Clinics (Japanese) 53

      Pages: 573-581

    • NAID

      10016424145

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16614014
  • [Journal Article] An adenosine A_<2A> receptor agonist induces sleep by increasing GABA release in the tuberomammillary nucleus to inhibit histaminergic systems in rats.2005

    • Author(s)
      Hong ZY, Huang ZL, Qu WM, Eguchi N, Urade Y, Hayaishi O.
    • Journal Title

      J Neurochem 92

      Pages: 1542-1549

    • Data Source
      KAKENHI-PROJECT-16614014
  • [Journal Article] An adenosine A_<2A> receptor agonist induces sleep by increasing GABA release in the tuberomammillary nucleus to inhibit histaminereic systems in rats.2005

    • Author(s)
      Hong ZY, Huang ZL, Qu WM, Eguchi N, Urade Y, Hayaishi O
    • Journal Title

      J Neurochem 92

      Pages: 1542-1549

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16614014
  • [Journal Article] Orexin A promotes histamine, but not noradrenaline or serotonin release, in the frontal cortex of mice.2005

    • Author(s)
      Hong ZY, Huang ZL, Qu WM, Eguchi N.
    • Journal Title

      Acta Pharmacol Sin 26(2)

      Pages: 155-159

    • Data Source
      KAKENHI-PROJECT-16614014
  • [Journal Article] Adenosine A2A, but not A1, receptors mediate the arousal effect of caffeine2005

    • Author(s)
      Huang ZL, et al.
    • Journal Title

      Nat Neurosci 8(7)

      Pages: 858-859

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16614014
  • [Journal Article] Adenosine A_<2A>, but not A_1, receptors mediate the arousal effect of caffeine.2005

    • Author(s)
      Huang, Z.-L., Qu, W.-M., Eguchi, N., Chen, J.-F., Schwarzschild, M.A., Fredholm, B.B., Urade, Y., Hayaishi, O.
    • Journal Title

      Nat.Neurosci. 8

      Pages: 858-859

    • Data Source
      KAKENHI-PROJECT-16300123
  • [Journal Article] Endogenous sleep-promoting substances. (Japanese)2005

    • Author(s)
      Urade Y, Huang ZL, Eguchi N
    • Journal Title

      The Jpn J Clini Exl Med 82(5)

      Pages: 93-97

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16614014
  • [Journal Article] Adenosine A_<2A>, but not A_1, receptors mediate the arousal effect of caffeine2005

    • Author(s)
      Huang, Z.-L., Qu, W-M., Eguchi, N., Chen, J.-F., Schwarzschild, M.A., Fredholm, B.B., Urade, Y., Hayaishi, O
    • Journal Title

      Nat.Neurosci. 8

      Pages: 858-859

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16300123
  • [Journal Article] An adenosine A_<2A> receptor agonist induces sleep by increasing GABA release in the tuberomammillary nucleus to inhibit histaminergic systems in rats.2005

    • Author(s)
      Hong, Z.-Y., Huang, Z.-L., Qu, W.-M., Eguchi, N., Urade, Y., Hayaishi, O.
    • Journal Title

      J.Neurochem. 92

      Pages: 1542-1549

    • Data Source
      KAKENHI-PROJECT-16300123
  • [Journal Article] An adenosine A_<2A> receptor agonist induces sleep by increasing GABA release in the tuberomammillary nucleus to inhibit histaminergic systems in rats.2005

    • Author(s)
      Hong ZY, Huang ZL, Qu WM, Eguchi N, Urade Y, Hayaishi O
    • Journal Title

      J Neurochem 92

      Pages: 1542-1549

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16300123
  • [Journal Article] An adenosine A_<2A> receptor agonist induces sleep by increasing GABA release in the tuberomammillary nucleus to inhibit histaminergic systems in rats.2005

    • Author(s)
      Hong ZY, Huang ZL, Qu WM, Eguchi N, Urade Y, Hayashi O.
    • Journal Title

      J Neurochem 92

      Pages: 1542-1549

    • Data Source
      KAKENHI-PROJECT-16300123
  • [Journal Article] Role of orexin and prostaglandin E_2 in activating histaminergic neurotransmission.2004

    • Author(s)
      Hayaishi O, Huang ZL
    • Journal Title

      Drug News Perspect 17(2)

      Pages: 105-109

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16614014
  • [Journal Article] Histaminergic role in sleep-wake cycle of orexin, adenosine, and prostaglandin E_2 and D_22004

    • Author(s)
      Huang ZL, et al.
    • Journal Title

      Sleep Biol Rhythm 2

      Pages: 21-22

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16614014
  • [Journal Article] Role of orexin and prostaglandin E_2 in activating histaminergic neurotransmission.2004

    • Author(s)
      Hayashi O, Huang ZL
    • Journal Title

      Drug News Perspect 17(2)

      Pages: 105-109

    • Data Source
      KAKENHI-PROJECT-16614014
  • [Journal Article] Extracellular histamine level in the frontal cortex is positively correlated with the amount of wakefulness in rats.2004

    • Author(s)
      Chu M, Huang ZL, Qu WM, Eguchi N, Yao MH, Urade Y.
    • Journal Title

      Neurosci Res 49

      Pages: 417-420

    • NAID

      10023900469

    • Data Source
      KAKENHI-PROJECT-16614014
  • [Journal Article] Genes for prostaglandin D synthase and receptor as well as adenosine A_<2A> receptor are involved in the homeostatic regulation of NREM sleep.2004

    • Author(s)
      Hayaishi O, Urade Y, Eguchi N, Huang ZL
    • Journal Title

      Arch Ital Biol 142

      Pages: 533-539

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16614014
  • [Journal Article] Role of orexin and prostaglandin E_2 in activating histaminergic neurotransmission.2004

    • Author(s)
      Hayaishi O, Huang ZL
    • Journal Title

      Drug News Perspect 17

      Pages: 105-109

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16300123
  • [Journal Article] Genes for prostaglandin D synthase and receptor as well as adenosine A_<2A> receptor are involved in the homeostatic regulation of NREM sleep.2004

    • Author(s)
      Hayashi O, Urade Y, Eguchi N, Huang ZL
    • Journal Title

      Arch Ital Biol 142

      Pages: 533-553

    • Data Source
      KAKENHI-PROJECT-16614014
  • [Journal Article] Role of orexin and prostaglandin E_2 in activating histaminergic neurotransmission2004

    • Author(s)
      Hayaishi, O, Huang ZL.
    • Journal Title

      Drug News Perspect 17(2)

      Pages: 105-109

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16614014
  • [Journal Article] Molecular mechanisms of sleep-wake regulation. (Japanese)2004

    • Author(s)
      Urade Y, Eguchi N, Huang ZL, Qu WM
    • Journal Title

      The Newest Medicine 59(3)

      Pages: 393-398

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16614014
  • [Journal Article] Histaminergic role in sleep-wake cycle of orexin, adenosine, and prostaglandin E_2 and D_2.2004

    • Author(s)
      Huang ZL, Qu WM, Eguchi N, Chu M, Okada T, Sato, Y, Sakata M, Mochizuki T, Urade Y, Hayaishi O
    • Journal Title

      Sleep Biol Rhythm 2

      Pages: 21-22

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16614014
  • [Journal Article] Genes for prostaglandin D synthase and receptor as well as adenosine A_<2A> receptor are involved in the homeostatic regulation of NREM sleep.2004

    • Author(s)
      Hayaishi O, Urade Y, Eguchi N, Huang ZL
    • Journal Title

      Arch Ital Biol 142

      Pages: 533-539

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16300123
  • [Journal Article] Histaminergic role in sleep-wake cycle of orexin, adenosine, and prostaglandin E2 and D2.2004

    • Author(s)
      Huang ZL, Qu WM, Eguchi N, Chu M, Okada T, Sato, Y, Sakata M, Mochizuki T, Urade Y, Hayaishi O
    • Journal Title

      Sleep Biol Rhythm 2

      Pages: 21-22

    • Data Source
      KAKENHI-PROJECT-16614014
  • [Journal Article] Genes for prostaglandin D synthase and receptor as well as adenosine A_<2A> receptor are involved in the homeostatic regulation of NREM sleep.2004

    • Author(s)
      Hayashi O, Urabe Y, Eguchi N, Huang ZL
    • Journal Title

      Arch Ital Biol 142

      Pages: 533-553

    • Data Source
      KAKENHI-PROJECT-16300123
  • [Journal Article] Role of orexin and prostaglandin E_2 in activating histaminergic neurotrallsmission.2004

    • Author(s)
      Hayaishi O, Huang ZL
    • Journal Title

      Drug News Perspect 17(2)

      Pages: 105-109

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16300123
  • [Journal Article] Role of orexin and prostaglandin E_2 in activating histaminergic neurotransmission.2004

    • Author(s)
      Hayaishi O, Huang ZL
    • Journal Title

      Drug News Perspect 17(2)

      Pages: 105-109

    • Data Source
      KAKENHI-PROJECT-16300123
  • [Journal Article] Extracellular histamine level in the frontal cortex is positively correlated with the amount of wakefulness in rats.2004

    • Author(s)
      Chu M, Huang ZL, Qu WM, Eguchi N, Yao MH, Urade Y
    • Journal Title

      Neurosci Res 49

      Pages: 417-420

    • NAID

      10023900469

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16614014
  • [Journal Article] Molecular mechanisms of sleep. (Japanses).2004

    • Author(s)
      Urade Y, Eguchi N, Huang ZL, Qu WM
    • Journal Title

      Clin Neurosci 22(1)

      Pages: 37-40

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16614014
  • [Patent] 睡眠改善薬2010

    • Inventor(s)
      裏出良博、黄志力, 他3名
    • Industrial Property Rights Holder
      株式会社クレイ沖縄
    • Industrial Property Number
      2010-062620
    • Filing Date
      2010-03-18
    • Data Source
      KAKENHI-PROJECT-21500313
  • [Patent] 睡眠改善剤および鎮静剤ならびにそれらの使用2010

    • Inventor(s)
      裏出良博、黄志力, 他5名
    • Industrial Property Rights Holder
      大阪バイオサイエンス研究所
    • Industrial Property Number
      2010-118339
    • Filing Date
      2010-05-24
    • Data Source
      KAKENHI-PROJECT-21500313
  • [Patent] 自立神経調節剤2009

    • Inventor(s)
      裏出良博、黄志力, 他6名
    • Industrial Property Rights Holder
      月桂冠株式会社
    • Industrial Property Number
      2009-288305
    • Filing Date
      2009-12-18
    • Data Source
      KAKENHI-PROJECT-21500313
  • [Presentation] Hypothalamic regulation of sleep-wake cycle, from basic research to drug discovery2012

    • Author(s)
      Zhi-Li Huang, Wei-Min Qu, Yoshihiro Urade
    • Organizer
      The 2012 Beijing Sleep Medicine Forum
    • Place of Presentation
      Beijing, China
    • Year and Date
      2012-05-13
    • Data Source
      KAKENHI-PROJECT-22300133
  • [Presentation] マウス脳における脂肪酸 結合タンパク質FABP7 の相互作用タンパ ク質の同定2012

    • Author(s)
      永田奈々恵、柏木香保里、山本利義、三 田村エリザベス、ミハエル・ラザルス、 黄 志力、藤森 功、宮本悦子、裏出良 博
    • Organizer
      第85回日本生化学大会
    • Place of Presentation
      福岡
    • Year and Date
      2012-12-15
    • Data Source
      KAKENHI-PROJECT-22300133
  • [Presentation] Sleep is regulated by prostaglandin D2 selectively produced in the meninges by lipocalin-type prostaglandin D synthase2012

    • Author(s)
      Yoan Cherasse, Yo Oishi, Michael Lazarus, Zhi-Li Huang, Osamu Hayaishi, Yoshihiro Urade
    • Organizer
      22^<nd> IUBMB
    • Place of Presentation
      Sevilla, Spain
    • Year and Date
      2012-09-06
    • Data Source
      KAKENHI-PROJECT-22300133
  • [Presentation] Key roles of dopamine D2 receptor in the sleep-wake regulation2012

    • Author(s)
      Zhi-Li Huang, Wei-Min Qu. Yoshihiro Urade
    • Organizer
      The 7^<th> Asian Sleep Research Society Congress
    • Place of Presentation
      Taipei, 台湾
    • Year and Date
      2012-11-30
    • Data Source
      KAKENHI-PROJECT-22300133
  • [Presentation] A novel SOX5 splicing isoform expressed in mouse brain during sleep2011

    • Author(s)
      Nanae Nagata, Kaori Kashiwagi, Toshiyoshi Yamamoto, Elizabeth P.Ko-Mitamura, Michael Lazarus, Zhi-Li-Huang, Ko Fujimori, Yoshihiro Urade
    • Organizer
      World Sleep 2011
    • Place of Presentation
      国立京都国際会館
    • Year and Date
      2011-09-04
    • Data Source
      KAKENHI-PROJECT-22300133
  • [Presentation] Dopamine D_2 receptors in the basal ganglia are essential in the maintenance of wakefulness2011

    • Author(s)
      Z.-L. Huang, W.-M. Qu, Yoshihiro Urade
    • Organizer
      8^<th> IBRO World Congress of Neuroscience
    • Place of Presentation
      Florence, Italy
    • Data Source
      KAKENHI-PROJECT-21500313
  • [Presentation] Dopamine D2 receptors in the basal ganglia are essential in the maintenance of wakefulness2011

    • Author(s)
      Z.-L. Huang, W.-M. Qu, Yoshihiro Urade
    • Organizer
      8^<th< IBRO World Congress of Neuroscience
    • Place of Presentation
      Florence, Italy
    • Data Source
      KAKENHI-PROJECT-22300133
  • [Presentation] A novel SOX5 splicing isoform expressed in mouse brain during sleep2011

    • Author(s)
      Nanae Nagata, Kaori Kashiwagi, Toshiyoshi Yamamoto, Elizabeth P. Ko-Mitamura, Michael Lazarus, Zhi-Li Hunag, Ko Fujmori, Yoshihiro Urade
    • Organizer
      Worldsleep 2011
    • Place of Presentation
      Kyoto, Japan
    • Data Source
      KAKENHI-PROJECT-22300133
  • [Presentation] Key roles of the histaminergic system for the somnogenic effect of prostaglandin D_2 and adenosine2011

    • Author(s)
      Zhi-Li Huang, Wei-Min Qu, Yoshihiro Urade, Osamu Hayaishi
    • Organizer
      Worldsleep 2011
    • Place of Presentation
      Kyoto, Japan
    • Data Source
      KAKENHI-PROJECT-21500313
  • [Presentation] Key roles of the histaminergic system for the somnogenic effect of prostaglandin D2 and adenosine2011

    • Author(s)
      Zhi-Li Huang, Wei-Min Qu, Yoshihiro Urade, Osamu Hayaishi
    • Organizer
      Worldsleep 2011
    • Place of Presentation
      Kyoto, Japan
    • Data Source
      KAKENHI-PROJECT-22300133
  • [Presentation] Roles of histaminergic systems in sleep-wake regulation2010

    • Author(s)
      Zhi-Li Huang, Wei-Min Qu, Yoshihiro Urade
    • Organizer
      2010 Beijing international sleep medicine forum
    • Place of Presentation
      Beijing, China
    • Year and Date
      2010-04-18
    • Data Source
      KAKENHI-PROJECT-22300133
  • [Presentation] The role of prostaglandin D_2 in causing post-ictal sleep following seizures2010

    • Author(s)
      Lazarus M, Kaushik MK, Moriyama T, Qu WM, Aritake K, Rahman MA, Huang ZL, Urade Y, Hayaishi O.
    • Organizer
      Neuroscience 2010【41th Annual Meeting of the Society for Neuroscience】
    • Place of Presentation
      ワシントン、米国
    • Data Source
      KAKENHI-PROJECT-21300133
  • [Presentation] Roles of histaminergic systems in sleep-wake regulation2010

    • Author(s)
      Zhi-Li Hung, Wei-Min QuYoshihiro Urade
    • Organizer
      2010 Beijing international sleep medicine forum
    • Place of Presentation
      Beijing, China
    • Year and Date
      2010-04-18
    • Data Source
      KAKENHI-PROJECT-21500313
  • [Presentation] 睡眠時に脳内で発 現する新規SOX5 スプライシングアイソ フォームの機能解析2010

    • Author(s)
      永田奈々恵、柏木香保里、山本利義、岡 崎一生、三田村エリザベス、Wei-Min Qu, Michael Lazarus, Zhi-Li Huang, 藤森 功、裏出良博
    • Organizer
      第33回日本神経 科学大会・第53回日本神経化学会大 会・第20回日本神経回路学会大会合同 大会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-22300133
  • [Presentation] Recent progress on sleep-wake promotiong substances: Prostaglandin D . and adenosine2010

    • Author(s)
      Yoshihiro Urade, Huang Zhi-Li
    • Organizer
      Turkish-Japanese Sleep Forum
    • Place of Presentation
      Izmir, Turkey
    • Year and Date
      2010-05-04
    • Data Source
      KAKENHI-PROJECT-22300133
  • [Presentation] Dopaminergic D_1 and D_2 receptors play a key role in the arousal effect of modafinil2009

    • Author(s)
      Zhi-Li Huang, Wei-Min Que, Yoshihiro Urade
    • Organizer
      9^<th> World Congress on Sleep Apnea
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2009-03-28
    • Data Source
      KAKENHI-PROJECT-21500313
  • [Presentation] Genetic Dissection of Histaminergic Systems Sleep-wake Cycle2009

    • Author(s)
      Huang ZL.
    • Organizer
      The 9^<th> World Congress on Sleep Apnea.
    • Place of Presentation
      Seoul, Korea.
    • Data Source
      KAKENHI-PROJECT-21500313
  • [Presentation] Interluekine-1. Induces sleep independent of prostaglandin D22008

    • Author(s)
      Wei-Min Qu, Zhi-Li Huang, Yoshihiro Urade and Osamu Hayaishi
    • Organizer
      日本睡眠学会第33回定期学術集会
    • Place of Presentation
      福島県郡山市
    • Data Source
      KAKENHI-PROJECT-19500283
  • [Presentation] Dopaminergic D_1 and D_2 receptors are essential for the arousal effect of modafinil2008

    • Author(s)
      Wei-Min Qu, Zhi-Li Huang, Naomi Matsumoto, Xin-Hong Xu, Yoshihiro Urade, Osamu Hayaishi
    • Organizer
      第31回日本神経科学大会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-19500283
  • [Presentation] Dopaminergic D1 and D2 receptors are essential for the arousal effect of modafinil2008

    • Author(s)
      Wei-Min Qu, Zhi-Li Huang, Naomi Matsumoto, Xin-Hong Xu, Yoshihiro Urade, and Osamu Hayaish
    • Organizer
      第31回日本神経科学大会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-19500283
  • [Presentation] Interluekine-1β induces sleep independent of prostaglandin D_22008

    • Author(s)
      Wei-Min Qu, Zhi-Li Huang, Yoshihiro Urade, Osamu Hayaishi
    • Organizer
      日本睡眠学会第33回定期学術集会
    • Place of Presentation
      福島県郡山市
    • Data Source
      KAKENHI-PROJECT-19500283
  • [Presentation] Genetic dissection of the role of histaminergic systems in sleep-wake regulation2007

    • Author(s)
      Huang ZL.
    • Organizer
      Annual Meeting for the Hong Kong Society of Sleep Medicine
    • Place of Presentation
      Hong Kong,China
    • Year and Date
      2007-09-29
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18603011
  • [Presentation] Adenosine A_2A Receptor Deficiency Attenuates the Somnogenic Effect of Prostaglandin D_22007

    • Author(s)
      Wei-Min Qu, Zhi-Li Huang, Yoshihiro Urade, Osamu Hayaishi
    • Organizer
      Worldsleep07, 5th world sleep congress of WFSRSMS
    • Place of Presentation
      Cairns, Australia
    • Data Source
      KAKENHI-PROJECT-19500283
  • [Presentation] Roles of the histaminergic system in sleep-wake regulation by prostaglandin, adenosine and or2007

    • Author(s)
      Huang ZL
    • Organizer
      Worldsleep07, Conference for World Sleep Research Society
    • Place of Presentation
      Cairns, Australia
    • Data Source
      KAKENHI-PROJECT-18603011
  • [Presentation] Sleep propensity is necessary for the sleep induction of histamine H1 receptor antagonist2007

    • Author(s)
      Huang, Z-L., Qu, W-M., Matsumoto, N., Wada, M., Urade, Y., Hayaishi, O.
    • Organizer
      The 32ad Annual Meeting of Japanes Sleep Research Society
    • Place of Presentation
      Tokyo, Japan
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18603011
  • [Presentation] Adenosine A2A Receptor Mainly Mediates the Somnogenic Effect of Prostaglandin D22007

    • Author(s)
      Wei-Min Qu, Zhi-Li Huang, Yoshihiro Urade, Osamu Hayaishi
    • Organizer
      日本睡眠学会第32回定期学術集会・第14回日本時間生物学会学術大会合同大会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-19500283
  • [Presentation] Prostaglandin D_2 system:recent progress in basic and clinical studies2007

    • Author(s)
      Huang ZL.
    • Organizer
      Worldsleep07: The 5th World Congress of the World, Federation of Sleep Research and Sleep Medicine Societies
    • Place of Presentation
      Cairns,Australia
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18603011
  • [Presentation] Genetic dissection of the role of histaminergic systems in sleep-wake regulation2007

    • Author(s)
      Huang ZL.
    • Organizer
      Annual Meeting for the Hong Kong Society of Sleep Medicine
    • Place of Presentation
      Hong Kong, China
    • Year and Date
      2007-09-29
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18603011
  • [Presentation] Roles of the histaminergic systems in sleep-wake regulation2007

    • Author(s)
      Huang ZL.
    • Organizer
      The 3rd CINP Asia-Pacific Regional Meeting
    • Place of Presentation
      Bangkok,Thailand
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18603011
  • [Presentation] Sleep propensity is necessary for the sleep induction of histamine H_1 receptor antagonist2007

    • Author(s)
      Huang,ZL.,Qu,WM.,Matsumoto,N.,Wada,M.,Urade,Y.& Hayaishi, O.
    • Organizer
      The 32nd Annual Meeting of Japanese Sleep Research Society
    • Place of Presentation
      Tokyo,Japan
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18603011
  • [Presentation] Adenosine A_<2A> Receptor Deficiency Attenuates the Somnogenic Effect of Prostaglandin D_22007

    • Author(s)
      Wei-Min Ou, Zhi-Li Huang, Yoshihiro Urade, Osamu Hayaishi
    • Organizer
      WorldsleepO7, 5th world sleep congress of WFSRSMS
    • Place of Presentation
      Cairns,Australia
    • Data Source
      KAKENHI-PROJECT-19500283
  • [Presentation] Prostaglandin D2 system : recent progress in basic and clinical studies2007

    • Author(s)
      Huang ZL.
    • Organizer
      Worldsleep07 : The 5th World Congress of the World, Federation of Sleep Research and Sleep Medicine Societies
    • Place of Presentation
      Cairns, Australia
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18603011
  • [Presentation] Roles of the histaminergic systems in sleep-wake regulation2007

    • Author(s)
      Huang ZL.
    • Organizer
      The 3rd CINP Asia-Pacific Regional Meeting
    • Place of Presentation
      Bangkok, Thailand
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18603011
  • [Presentation] Adenoslne A_<2A>Receptor Mainly Mediates the Somnogenic Effect of Prostaglandin D_22007

    • Author(s)
      Wei-Min Qu, Zhi-Li Huang, Yoshihiro Urade, Osamu Hayaishi
    • Organizer
      日本睡眠学会第32回定期学術集会・第14回日本時間生物学会学術大会合同大会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-19500283
  • [Presentation] Alterations of sleep-wake behavioral characteristics and lack of arousal response to H3 receptor antagonist in histamine H1 receptor knockout mice2006

    • Author(s)
      Huang, Z.L., Mochizuki, T., Qu, W. M., Hong, Z. Y., Watanabe, T., Urade, Y., Hayaishi, O.
    • Organizer
      The 20th International Congress of Biochemistry and Molecular Biology
    • Place of Presentation
      Kyoto, Japan
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18603011
  • [Presentation] Alterations of sleep-wake behavioral characteristics and lack of arousal response to H_3 receptor antagonist in histamine H_1 receptor knockout mice2006

    • Author(s)
      Huang,Z.L.,Mochizuki,T.,Qu,W.M.,Hong,Z.Y.,Watanabe,T.,Urade,Y.&Hayaishi,O.
    • Organizer
      The 20th International Congress of Biochemistry and Molecular Biology
    • Place of Presentation
      Kyoto,Japan
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18603011
  • 1.  URADE Yoshihiro (10201360)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 90 results
  • 2.  WEI Min Qu (20332231)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 49 results
  • 3.  HAYAISHI Osamu (40025507)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 58 results
  • 4.  ARITAKE Kosuke (70390804)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 1 results
  • 5.  EGUCHI Naomi (10250086)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 27 results
  • 6.  WADA Masashi (80421379)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 7.  FUJIMORI Ko (70425453)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 8.  NAGATA Nanae (80390805)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 4 results
  • 9.  HOSHIKAWA Yumiko (10390808)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  MARUYAMA Toshihiko (70414133)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  LAZARUS Michael (80469650)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 12.  OISHI Yo (70554004)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  MATSUMOTO Naomi (60450243)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  CHERASSE Yoan (60544319)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 15.  MITAMURA Ko elizabeth (20450249)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  KASHIWAGI Kaori (10372666)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 17.  SAKATA Mie (10353525)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  INOUE Teruo (20168454)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  EGUCHI Yutaka (00263054)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  毛利 育子 (70399351)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  福本 典子 (20390809)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  邵 奇妙 (10450248)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  竹之下 真 (00144486)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  KAUSHIK Mahesh
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 25.  裏出 令子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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