Yamada Masami 山田雅巳

… Alternative Names

山田雅巳ヤマダマサミ

YAMADA Masami 山田雅巳

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Researcher Number	10322851
Other IDs
Affiliation (Current)	2025: 福井大学, 学術研究院医学系部門, 教授
Affiliation (based on the past Project Information) *help	2021 – 2023: 福井大学, 学術研究院医学系部門, 教授 2016 – 2017: 福井大学, 学術研究院医学系部門, 教授 2015: 大阪市立大学, 大学院医学研究科, 准教授 2014: 大阪市立大学, 医学(系)研究科(研究院), 准教授 2012: 大阪市立大学, 医学(系)研究科(研究院), 准教授 … More 2010 – 2012: 大阪市立大学, 大学院・医学研究科, 准教授 2002: 北海道大学, 遺伝子病制御研究所, 助手 2000: Hokkaido Univ.Institute for Genetic Medicine. Assistant professor, 遺伝子病制御研究所, 助手 Less
Review Section/Research Field	Principal Investigator General medical chemistry / Biological Sciences Except Principal Investigator Virology / Basic Section 56010:Neurosurgery-related / General medical chemistry / Biological Sciences
Keywords	Principal Investigator カルパイン阻害薬 / 細胞質ダイニン / 細胞内物質輸送 / LIS1 / 微小管モータータンパク質 / 滑脳症 / 神経細胞遊走障害 / 細胞内ロジスティクス / 低分子量GTPase Rab6 / 神経細胞遊走 … More / 神経遊走 / 遺伝性神経疾患 / 微小管関連因子 / 精神発達遅滞 / 精神・神経疾患 / 創薬スクリーニング / 神経細胞遊走（移動）障害 / αーシヌクレイン / 発達障害 / 微小管分子モーター / クラスIIIベータ－チューブリン / mNUDC / 神経細胞移動障害 / α-シヌクレイン / クラスIIIβ-チューブリン / 蛍光分子イメージング / シヌクレイン / 微小管 / 微小管モーター / 神経変性疾患 / 量子ドット / 蛍光相互相関分光法(FCCS) / 低分子量GTPase Rab6a / タンパク質分解酵素 / カルパイン阻害薬 / カルパイン阻害剤 … More Except Principal Investigator CRM1 / Rex / Rev / HTLV-1 / ラット / 細胞内ダイナミクス / インポーティンα１ / 膠芽腫 / 遊走能 / Glioblastoma / CADM1 / インポーティンα1 / 接着因子 / 遊走 / インポーティン / 核-細胞質間輸送 / 滑脳症・小脳症 / 神経幹細胞の増殖 / 神経細胞の遊走 / 神経幹細胞の分裂 / microlissencephaly / α-Synuclein / 微小管ネットワーク / NuMA / 細胞質ダイニン / カタニンp80 / 中枢神経形成不全 / Infection animal model / rat / 感染動物モデル / hepatitis B virus / multimerization / RNA transport / mRNA輸送 / レトロウイルス / B型肝炎ウイルス / 多量体化 / RNA輸送 / HIV Less

Elucidation of the dynamics related to intracellular importin-alpha1 in the acceleration of migration of glioblastoma
- Principal Investigator
  
  Takahiro Yamauchi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  University of Fukui
Drug screening for genetic diseases that occur in conjunction with neuronal migration disorders.Principal Investigator
- Principal Investigator
  
  Yamada Masami
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General medical chemistry
- Research Institution
  University of Fukui
  Osaka City University
Clarify the pathogenic mechnism of microlissencephaly
- Principal Investigator
  
  Jin Mingyue
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Osaka City University
Intracellular logistics of LIS1-cytoplasmic dynein in lissencephaly.Principal Investigator
- Principal Investigator
  
  Yamada Masami
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  University of Fukui
  Osaka City University
ＬＩＳ１による細胞内ロジスティックスと滑脳症発症の関係Principal Investigator
- Principal Investigator
  
  山田雅巳
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka City University
New strategy for lissencephaly therapeutic medicine development.Principal Investigator
- Principal Investigator
  
  YAMADA Masami
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Osaka City University
HIV/HTLV-1高感受性のヒトCRM1を発現するトランスジェニックラット
- Principal Investigator
  
  SHIDA Hisatoshi
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Hokkaido University
Construction of a transgenic rat model, which is highly sensitive to HTLV-1 infection
- Principal Investigator
  
  SHIDA Hisatoshi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Virology
- Research Institution
  HOKKAIDO UNIVERSITY
Cellular cofactors involved in transport of mRNAs of complex retroviruses and hepatitis B virus
- Principal Investigator
  
  SHIDA Hisatoshi
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Virology
- Research Institution
  HOKKAIDO UNIVERSITY

All 2017 2016 2015 2014 2013 2012 2011 2010 Other

All Journal Article Presentation Patent

[Journal Article] 先天性神経疾患に対する新しい治療戦略2017
- Author(s)
  山田雅巳
- Journal Title
  
  ブレインサイエンス・レビュ－
  
  Volume: 2017 Pages: 283-304
- Data Source
  KAKENHI-PROJECT-15K15071
[Journal Article] Alpha-synuclein facilitates to form short unconventional microtubules that have a unique function in the axonal transport2017
- Author(s)
  Toba Shiori、Jin Mingyue、Yamada Masami、Kumamoto Kanako、Matsumoto Sakiko、Yasunaga Takuo、Fukunaga Yuko、Miyazawa Atsuo、Fujita Sakiko、Itoh Kyoko、Fushiki Shinji、Kojima Hiroaki、Wanibuchi Hideki、Arai Yoshiyuki、Nagai Takeharu、Hirotsune Shinji
- Journal Title
  
  Sci Rep
  
  Volume: 7 Issue: 1 Pages: 16386-16386
- DOI
  10.1038/s41598-017-15575-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09162, KAKENHI-PROJECT-17K15603, KAKENHI-PROJECT-17H04047, KAKENHI-PROJECT-15K08283
[Journal Article] Alpha-synuclein binds unconventional microtubules that have a unique function.2017
- Author(s)
  Shiori Toba, Mingyue Jin, Masami Yamada, Kanako Kumamoto, Sakiko Matsumoto, Takuo Yasunaga, Yuko Fukunaga, Atsuo Miyazawa, Sakiko Fujita, Kyoko Itoh, Shinji Fushiki, Kojima Hiroaki, Hideki Wanibuchi, Yoshiyuki Arai, Takeharu Nagai, Shinji Hirotsune
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Pages: 1-19
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26293066
[Journal Article] 先天性神経疾患に対する新しい治療戦略2017
- Author(s)
  山田雅巳
- Journal Title
  
  ブレインサイエンス・レビュ－
  
  Volume: 2017 Pages: 283-304
- Data Source
  KAKENHI-PROJECT-26293066
[Journal Article] LIS1 の微小管モーター制御と滑脳症発症機構の解明2015
- Author(s)
  山田雅巳、永井健治、新井由之、金明月、広常真治
- Journal Title
  
  物質・デバイス領域共同研究拠点　研究成果報告集
  
  Volume: 2014334 Pages: 1-2
- Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26293066
[Journal Article] LIS1 の微小管モーター制御と滑脳症発症機構の解明2015
- Author(s)
  山田雅巳
- Journal Title
  
  物質・デバイス領域共同研究拠点　研究成果報告集
  
  Volume: 2014334 Pages: 1-2
- Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K15071
[Journal Article] LIS1 の微小管モーター制御と滑脳症発症機構の解明2015
- Author(s)
  山田雅巳
- Journal Title
  
  月刊「化学工業」
  
  Volume: 66 Pages: 44-50
- Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K15071
[Journal Article] LIS1 の微小管モーター制御と滑脳症発症機構の解明2015
- Author(s)
  山田雅巳
- Journal Title
  
  月刊「化学工業」
  
  Volume: 66 Pages: 44-50
- Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26293066
[Journal Article] Arl3 and LC8 regulate dissociation of dynactin from dynein.2014
- Author(s)
  Jin M, Yamada M, Arai Y, Nagai T, Hirotsune S.
- Journal Title
  
  Nat Commun.
  
  Volume: 5 Issue: 1 Pages: 5295-5295
- DOI
  10.1038/ncomms6295
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-24113007, KAKENHI-PROJECT-26293066
[Journal Article] Intracellular logistics regulated by LIS1 and lissencephaly.2014
- Author(s)
  Masami Yamada
- Journal Title
  
  The NOVARTIS Foundation (Japan) for the Promotion of Science, Annual Report
  
  Volume: 26 Pages: 52-55
- Data Source
  KAKENHI-PROJECT-26293066
[Journal Article] LIS1による細胞内ロジスティクスと滑脳症発症メカニズム2013
- Author(s)
  山田雅巳
- Journal Title
  
  新学術領域研究・細胞内ロジスティクス班・ニュースレター
  
  Volume: 3 Pages: 3-7
- Data Source
  KAKENHI-PUBLICLY-23113723
[Journal Article] LIS1による細胞内ロジスティクスと滑脳症発症メカニズム2013
- Author(s)
  山田雅巳
- Journal Title
  
  新学術領域研究・細胞内ロジスティクス班・ニュースレター
  
  Volume: 3 Pages: 3-7
- Data Source
  KAKENHI-PROJECT-22390056
[Journal Article] LIS1による細胞内ロジスティクスと滑脳症発症メカニズム2013
- Author(s)
  山田雅巳
- Journal Title
  
  新学術領域研究・細胞内ロジスティクス班・ニュースレター
  
  Pages: 3-7
- Data Source
  KAKENHI-PROJECT-22390056
[Journal Article] Post-natal therapeutic intervention for lissencephaly using a blood-brain-barrier permeable calpain inhibitor2013
- Author(s)
  Shiori Toba, Yasuhisa Tamura, Kanako Kumamoto, Masami Yamada, Keizo Takao, Satoko Hattori, Tsuyoshi Miyakawa, Yosky Kataoka, Mitsuyoshi Azuma, Kiyoshi Hayasaka, Masano Amamoto, Keiko Tominaga, Anthony Wynshaw-Boris, Mitsuhiro Kato and Shinji Hirotsune
- Journal Title
  
  SNJ1945 Scientific Reports
  
  Volume: 3 Issue: 1 Pages: 1224-1224
- DOI
  10.1038/srep01224
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390056, KAKENHI-PROJECT-23659092, KAKENHI-PUBLICLY-24111546, KAKENHI-PROJECT-24700352, KAKENHI-PUBLICLY-25123704, KAKENHI-PROJECT-25460399, KAKENHI-PROJECT-221S0001, KAKENHI-PUBLICLY-23113723, KAKENHI-PLANNED-24113007
[Journal Article] カルパイン阻害剤による滑脳症の治療2011
- Author(s)
  山田雅巳
- Journal Title
  
  上原記念生命科学財団・研究報告集
  
  Volume: vol.25 Pages: 71-71
- Data Source
  KAKENHI-PROJECT-22390056
[Journal Article] 蛍光一分子イメージングを用いたLIS1の細胞内ロジスティクスと滑脳症発症機構の解明2011
- Author(s)
  山田雅巳
- Journal Title
  
  物質・デバイス領域共同研究拠点研究成果報告集
  
  Pages: 77-78
- Data Source
  KAKENHI-PROJECT-22390056
[Journal Article] LIS1による細胞内ロジスティクスと滑脳症発症の関係2011
- Author(s)
  山田雅巳
- Journal Title
  
  生物物理
  
  Volume: 51(6) Pages: 268-269
- NAID
  10030037995
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390056
[Journal Article] LIS1による細胞内ロジスティクスと滑脳症発症の関係2011
- Author(s)
  山田雅巳
- Journal Title
  
  生物物理
  
  Volume: 51(6) Pages: 268-269
- NAID
  10030037995
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23113723
[Journal Article] LIS1による細胞内ロジスティクスと滑脳症の関係2011
- Author(s)
  山田雅巳
- Journal Title
  
  生物物理
  
  Volume: vol.51(6) Pages: 268-269
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390056
[Journal Article] A therapeutic intervention of gene disease by augmented recycling of target genes.2010
- Author(s)
  Masami Yamada, Shinji Hirotsune, Anthony Wynshaw-Boris
- Journal Title
  
  Future Neurology
  
  Volume: 5 Pages: 5-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390056
[Journal Article] A novel strategy for therapeutic intervention for the genetic disease ; Preventing proteolytic cleavage using small chemical compound.2010
- Author(s)
  Masami Yamada, Shinji Hirotsune, Anthony Wynshaw-Boris
- Journal Title
  
  The International Journal of Biochemistry and Cell Biology
  
  Volume: 42 Pages: 1401-1407
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390056
[Journal Article] The essential role of LIS1, NDEL1 and Aurora-A in polarity formation and microtubules organization during neurogenesis.2010
- Author(s)
  Masami Yamada, Shinji Hirotsune and Anthony Wynshaw-Boris
- Journal Title
  
  Focal Adhesion and migration
  
  Volume: vol. 4(2) Pages: 180-184
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390056
[Journal Article] A therapeutic intervention of gene disease by augmented recycling of target genes.2010
- Author(s)
  Masami Yamada, Shinji Hirotsune and Anthony Wynshaw-Boris
- Journal Title
  
  Future Neurology
  
  Volume: vol. 5(1) Pages: 5-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390056
[Journal Article] A novel strategy for therapeutic intervention for the genetic disease; Preventing proteolytic cleavage using small chemical compound.2010
- Author(s)
  Masami Yamada, Shinji Hirotsune and Anthony Wynshaw-Boris
- Journal Title
  
  The International Journal of Biochemistry and Cell Biology
  
  Volume: vol. 42(9) Pages: 1401-1407
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390056
[Journal Article] Functional dissection on LIS1 and NDEL1 towards understanding the molecular mechanism of cytoplasmic dynein regulation.2010
- Author(s)
  Takayuki Torisawa, Akiko Nakayama, Ken'ya Furuta, Masami Yamada, Shinji Hirotsune, Yoko Y.Toyoshima
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 286 Pages: 1959-1965
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390056
[Journal Article] The essential role of LIS1, NDEL1 and Aurora-A in polarity formation and microtubules organization during neurogenesis.2010
- Author(s)
  Masami Yamada, Shinji Hirotsune, Anthony Wynshaw-Boris
- Journal Title
  
  Focal Adhesion and migration
  
  Volume: 4 Pages: 180-184
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390056
[Journal Article] Rab6a releases LIS1 from a dynein idling complex and activates dynein for retrograde movement.
- Author(s)
  Masami Yamada, Kanako Kumamoto, Shintaro Mikuni, Yoshiyuki Arai, Masataka Kinjo, Takeharu Nagai, Yoshikazu Tsukasaki, Tomonobu M. Watanabe, Mitsuru Fukui, Mingyue Jin, Shiori Toba and Shinji Hirotsune
- Journal Title
  
  Nature Communications
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390056
[Patent] 神経遊走傷害を伴う遺伝疾患治療薬のスクリーニング法2016
- Inventor(s)
  山田雅巳
- Industrial Property Rights Holder
  大阪市立大学
- Industrial Property Rights Type
  特許
- Filing Date
  2016-01-19
- Data Source
  KAKENHI-PROJECT-15K15071
[Patent] 神経細胞の遊走障害を伴う疾患の判定方法2016
- Inventor(s)
  山田雅巳
- Industrial Property Rights Holder
  大阪市立大学
- Industrial Property Rights Type
  特許
- Filing Date
  2016-01-19
- Data Source
  KAKENHI-PROJECT-26293066
[Patent] 神経細胞の遊走障害を伴う疾患の判別方法2013
- Inventor(s)
  山田雅巳
- Industrial Property Rights Holder
  大阪市立大学
- Industrial Property Rights Type
  特許
- Filing Date
  2013-02-05
- Data Source
  KAKENHI-PROJECT-22390056
[Patent] 神経細胞の遊走障害を伴う疾患の判別方法2013
- Inventor(s)
  山田雅巳
- Industrial Property Rights Holder
  大阪市立大学
- Industrial Property Rights Type
  特許
- Filing Date
  2013-02-05
- Data Source
  KAKENHI-PUBLICLY-23113723
[Patent] 神経細胞の遊走障害を伴う疾患の判定方法2013
- Inventor(s)
  山田雅巳
- Industrial Property Rights Holder
  大阪市立大学
- Filing Date
  2013-02-05
- Data Source
  KAKENHI-PROJECT-22390056
[Presentation] Intracellular logistics of LIS1, cytoplasmic dynein, and unconventional microtubules.2017
- Author(s)
  Masami Yamada
- Organizer
  2017 ASCB (American Society of Cell Biology) Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293066
[Presentation] Intracellular logistics of LIS1 and cytoplasmic dynein and lissencephaly.2017
- Author(s)
  Masami Yamada
- Organizer
  2017 EMBO/EMBL Symposium (Seeing is Believing),
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293066
[Presentation] Intracellular logistics of LIS1 and cytoplasmic dynein in lissencephaly.2016
- Author(s)
  Masami Yamada
- Organizer
  ２０１６ ASCB (American Society of Cell Biology) Annual Meeting
- Place of Presentation
  Moscone Center (San Francisco, CA, USA)
- Year and Date
  2016-12-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293066
[Presentation] インビトロ神経細胞遊走活性を指標とした新規創薬探索2016
- Author(s)
  山田雅巳
- Organizer
  「メディカルジャパン2016」セミナー関西広域連合（研究成果発表会）
- Place of Presentation
  インテックス大阪センタービル（大阪府大阪市）
- Year and Date
  2016-02-24
- Invited
- Data Source
  KAKENHI-PROJECT-26293066
[Presentation] インビトロ神経細胞遊走活性を指標とした新規創薬探索2016
- Author(s)
  山田雅巳
- Organizer
  「メディカルジャパン2016」セミナー関西広域連合（研究成果発表会）
- Place of Presentation
  インテックス大阪センタービル（大阪府大阪市）
- Year and Date
  2016-02-24
- Invited
- Data Source
  KAKENHI-PROJECT-15K15071
[Presentation] インビトロ神経細胞遊走活性を指標とした新規創薬探索2016
- Author(s)
  山田雅巳
- Organizer
  DSANJ疾患別商談会
- Place of Presentation
  大阪産業創造館（大阪府大阪市）
- Year and Date
  2016-01-29
- Data Source
  KAKENHI-PROJECT-15K15071
[Presentation] Intracellular logistics of LIS1 and cytoplasmic dynein in lissencephaly.2016
- Author(s)
  山田雅巳
- Organizer
  2016 ASCB (American Society of Cell Biology) Annual Meeting
- Place of Presentation
  Moscone Center (San Francisco, CA, USA)
- Year and Date
  2016-12-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15071
[Presentation] インビトロ神経細胞遊走活性を指標とした新規創薬探索2016
- Author(s)
  山田雅巳
- Organizer
  DSANJ疾患別商談会
- Place of Presentation
  大阪産業創造館（大阪府大阪市）
- Year and Date
  2016-01-29
- Data Source
  KAKENHI-PROJECT-26293066
[Presentation] LIS1の微小管モーター制御と滑脳症発症機構の解明2016
- Author(s)
  山田雅巳
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-03-11
- Data Source
  KAKENHI-PROJECT-15K15071
[Presentation] LIS1の微小管モーター制御と滑脳症発症機構の解明2016
- Author(s)
  山田雅巳
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-03-11
- Data Source
  KAKENHI-PROJECT-26293066
[Presentation] インビトロ神経細胞遊走活性を指標とした新規創薬探索2016
- Author(s)
  山田雅巳
- Organizer
  ライフサイエンスワールド２０１６　第１３回アカデミックフォーラム
- Place of Presentation
  東京ビッグサイト（東京）
- Year and Date
  2016-05-12
- Data Source
  KAKENHI-PROJECT-26293066
[Presentation] インビトロ神経細胞遊走活性を指標とした新規創薬探索2016
- Author(s)
  山田雅巳
- Organizer
  ライフサイエンスワールド2016　第13回アカデミックフォーラム
- Place of Presentation
  東京ビッグサイト（東京）
- Year and Date
  2016-05-12
- Data Source
  KAKENHI-PROJECT-15K15071
[Presentation] A regulatory mechanism of cargo unloading: Arl3 and LC8 coordinately induce dissociation of the dynein-dynactin.2015
- Author(s)
  山田雅巳
- Organizer
  第67回日本細胞生物学会大会
- Place of Presentation
  タワーホール船堀（東京都江戸川区）
- Year and Date
  2015-07-02
- Data Source
  KAKENHI-PROJECT-26293066
[Presentation] インビトロ神経細胞遊走活性を指標とした新規創薬探索2015
- Author(s)
  山田雅巳
- Organizer
  イノベーション・ジャパン2015-大学見本市
- Place of Presentation
  東京ビッグサイト（東京都江東区）
- Year and Date
  2015-08-27
- Data Source
  KAKENHI-PROJECT-26293066
[Presentation] インビトロ神経細胞遊走活性を指標とした新規創薬探索2015
- Author(s)
  山田雅巳
- Organizer
  イノベーション・ジャパン2015-大学見本市
- Place of Presentation
  東京ビッグサイト（東京都江東区）
- Year and Date
  2015-08-27
- Data Source
  KAKENHI-PROJECT-15K15071
[Presentation] インビトロ神経細胞遊走活性を指標とした新規創薬探索2015
- Author(s)
  山田雅巳
- Organizer
  第35回バイオ技術シーズ公開会
- Place of Presentation
  大阪科学技術センター（大阪府大阪市）
- Year and Date
  2015-12-02
- Invited
- Data Source
  KAKENHI-PROJECT-26293066
[Presentation] インビトロ神経細胞遊走活性を指標とした新規創薬探索2015
- Author(s)
  山田雅巳
- Organizer
  第35回バイオ技術シーズ公開会
- Place of Presentation
  大阪科学技術センター（大阪府大阪市）
- Year and Date
  2015-12-02
- Invited
- Data Source
  KAKENHI-PROJECT-15K15071
[Presentation] LIS1-細胞質ダイニンの分子ダイナミクスと滑脳症発症機構の解明2015
- Author(s)
  山田雅巳
- Organizer
  第5回物質・デバイス領域共同研究拠点活動報告会
- Place of Presentation
  九州大学伊都キャンパスカーボン・ニュートラルエネルギー国際研究所（福岡県・福岡市）
- Year and Date
  2015-04-20
- Invited
- Data Source
  KAKENHI-PROJECT-26293066
[Presentation] A regulatory mechanism of cargo unloading: Arl3 and LC8 coordinately induce dissociation of the dynein-dynactin.2015
- Author(s)
  山田雅巳
- Organizer
  第67回日本細胞生物学会大会
- Place of Presentation
  タワーホール船堀（東京都江戸川区）
- Year and Date
  2015-07-02
- Data Source
  KAKENHI-PROJECT-15K15071
[Presentation] Arl3およびLC8による細胞質ダイニン-ダイナクチン輸送複合体からのCargo荷下しの分子制御機構2015
- Author(s)
  山田雅巳
- Organizer
  第38回日本分子生物学会・第88回日本生化学会合同大会
- Place of Presentation
  神戸国際展示場（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26293066
[Presentation] Arl3およびLC8による細胞質ダイニン-ダイナクチン輸送複合体からのCargo荷下しの分子制御機構2015
- Author(s)
  山田雅巳
- Organizer
  第38回日本分子生物学会・第88回日本生化学会合同大会
- Place of Presentation
  神戸国際展示場（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K15071
[Presentation] インビトロ神経細胞遊走活性を指標とした新規創薬探索2014
- Author(s)
  山田雅巳
- Organizer
  科学技術振興機構(JST)・新技術説明会
- Place of Presentation
  科学技術振興機構(JST)東京本部別館（東京都・千代田区）
- Year and Date
  2014-11-21
- Invited
- Data Source
  KAKENHI-PROJECT-26293066
[Presentation] カルパイン阻害薬のin vitro神経細胞遊走活性による探索2013
- Author(s)
  山田雅巳
- Organizer
  科学技術振興機構(JST)・新技術説明会優良シーズ発表会
- Place of Presentation
  東京
- Year and Date
  2013-02-25
- Data Source
  KAKENHI-PROJECT-22390056
[Presentation] 低分子量GTPase Rab6Aによる細胞質ダイニンの活性化メカニズムの解析2012
- Author(s)
  山田雅巳
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  マリンメッセ福岡
- Year and Date
  2012-12-16
- Data Source
  KAKENHI-PUBLICLY-23113723
[Presentation] LIS1による細胞内ロジスティックスと滑脳症発症の関係文部科学省科学研究費「新学術領域研究」2012
- Author(s)
  山田雅巳
- Organizer
  第4回「細胞内ロジスティックス」班会議
- Place of Presentation
  仙台
- Year and Date
  2012-06-15
- Data Source
  KAKENHI-PROJECT-22390056
[Presentation] ＬＩＳ１による細胞内ロジスティクスと滑脳症発症の関係2012
- Author(s)
  山田雅巳
- Organizer
  第4回新学術領域研究「細胞内ロジスティックス」班会議
- Place of Presentation
  仙台市太白区秋保町秋保温泉岩沼屋
- Year and Date
  2012-06-15
- Data Source
  KAKENHI-PUBLICLY-23113723
[Presentation] Rab6a releases LIS1 from a dynein idling complex and activates dynein for retrograde movement.2012
- Author(s)
  Masami Yamada
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Year and Date
  2012-12-13
- Data Source
  KAKENHI-PROJECT-22390056
[Presentation] 低分子量GTPase Rab6Aによる細胞質ダイニンの活性化メカニズムの解析2012
- Author(s)
  山田雅巳
- Organizer
  第35回日本分子生物学会
- Place of Presentation
  マリンメッセ福岡
- Year and Date
  2012-12-13
- Data Source
  KAKENHI-PUBLICLY-23113723
[Presentation] Rab6a releases LIS1 from a dynein idling complex and activates dynein for retrograde movement.2012
- Author(s)
  Masami Yamada
- Organizer
  第85回日本生化学会年会
- Place of Presentation
  福岡
- Year and Date
  2012-12-16
- Data Source
  KAKENHI-PROJECT-22390056
[Presentation] Inhibition of calpain increases LIS1(PAFAHIB1) and partially rescues in vivo phenotypes in a mouse model of lissence2011
- Author(s)
  山田雅巳
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシッコ横浜(横浜)
- Year and Date
  2011-12-17
- Data Source
  KAKENHI-PUBLICLY-23113723
[Presentation] LIS1による細胞内ロジスティックスと滑脳症発症の関係2011
- Author(s)
  山田雅巳
- Organizer
  新学術領域研究第3回細胞内ロジスティクス班会議
- Place of Presentation
  鳥羽シーサイドホテル(三重)
- Year and Date
  2011-06-01
- Data Source
  KAKENHI-PUBLICLY-23113723
[Presentation] Inhibition of calpain increases LIS1 (PAFAH1B1) and partially rescues in vivo phenotypes in a mouse model of lissencephaly2011
- Author(s)
  山田雅巳
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都国際会館(京都)
- Year and Date
  2011-09-23
- Data Source
  KAKENHI-PROJECT-22390056
[Presentation] Inhibition of calpain increases LIS1(PAFAH1B1) and partially rescues in vivo phenotypes in a mouse model of lissencephaly.2011
- Author(s)
  Masami Yamada
- Organizer
  第63回日本細胞生物学会大会
- Place of Presentation
  札幌
- Year and Date
  2011-06-29
- Data Source
  KAKENHI-PROJECT-22390056
[Presentation] Inhibition of calpain increases LIS1(PAFAH1B1) and partially rescues in vivo phenotypes in a mouse model of lissencephaly.2011
- Author(s)
  Masami Yamada, Takako Takitoh, Shinji Hirotsune
- Organizer
  第84回日本生化学会年会
- Place of Presentation
  京都
- Year and Date
  2011-09-23
- Data Source
  KAKENHI-PROJECT-22390056
[Presentation] Inhibition of calpain increases LIS1(PAFAH1B1) and partially rescues in vivo phenotypes in a mouse model of lissence2011
- Author(s)
  山田雅巳
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都国際会館(京都)
- Year and Date
  2011-09-23
- Data Source
  KAKENHI-PUBLICLY-23113723
[Presentation] LIS1による細胞内ロジスティックス滑脳症発症の関係文部科学省科学研究費「新学術領域研究」2011
- Author(s)
  山田雅巳
- Organizer
  第3回「細胞内ロジスティックス」班会議
- Place of Presentation
  三重
- Year and Date
  2011-06-01
- Data Source
  KAKENHI-PROJECT-22390056
[Presentation] Inhibition of calpain increases LIS1 (PAFAH1B1) and partially rescues in vivo phenotypes in a mouse model of lissencephaly2011
- Author(s)
  山田雅巳
- Organizer
  第63回日本細胞生物学会大会
- Place of Presentation
  札幌(北海道大学)
- Year and Date
  2011-06-29
- Data Source
  KAKENHI-PROJECT-22390056
[Presentation] Inhibition of calpain increases LIS1(PAFAH1B1) and partially rescues in vivo phenotypes in a mouse model of lissencephaly.2011
- Author(s)
  Masami Yamada, Takako Takitoh, Shinji Hirotsune
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-12-17
- Data Source
  KAKENHI-PROJECT-22390056
[Presentation] Inhibition of calpain increases LIS1 (PAFAH1B1) and partially rescues in viro phenotypes in a mouse model of lissencephaly2011
- Author(s)
  山田雅巳
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシッコ横浜(横浜)
- Year and Date
  2011-12-17
- Data Source
  KAKENHI-PROJECT-22390056
[Presentation] LIS1による細胞内ロジスティックスと滑脳症発症の関係2011
- Author(s)
  山田雅巳
- Organizer
  新学術領域研究第3回細胞内ロジスティクス班会議
- Place of Presentation
  鳥羽シーサイドホテル(三重)
- Year and Date
  2011-06-01
- Data Source
  KAKENHI-PROJECT-22390056
[Presentation] Inhibition of calpain increases LIS1(PAFAH1B1) and partially rescues in vivo phenotypes in a mouse model of lissence2011
- Author(s)
  山田雅巳
- Organizer
  第63回日本細胞生物学会大会
- Place of Presentation
  札幌(北海道大学)
- Year and Date
  2011-06-29
- Data Source
  KAKENHI-PUBLICLY-23113723
[Presentation] A novel mechanism of plus-end- directed transport of cytoplasmic dynein and dynactins by kinesin-1.The role(s) of LIS1 and mNUDC in this process.2010
- Author(s)
  Masami Yamada
- Organizer
  International Symposium on Single-molecule nano detection and its application to life science
- Place of Presentation
  Hyogo, Awaji
- Year and Date
  2010-04-17
- Data Source
  KAKENHI-PROJECT-22390056
[Presentation] タンパク質分解酵素カルパインの阻害薬は滑脳症モデル(LIS1ヘテロ欠損) マウスにおいてその症状を改善した2010
- Author(s)
  山田雅巳
- Organizer
  大阪市医学会例会
- Place of Presentation
  大阪市立大学医学部
- Year and Date
  2010-10-21
- Data Source
  KAKENHI-PROJECT-22390056
[Presentation] 低分子量GTPase Rab6Aによる細胞質ダイニンの活性化メカニズムの解析
- Author(s)
  山田雅巳
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  マリンメッセ福岡
- Data Source
  KAKENHI-PROJECT-22390056
[Presentation] 滑脳症発症機構に於ける細胞内物流の役割
- Author(s)
  山田雅巳
- Organizer
  第66回日本細胞生物学会大会
- Place of Presentation
  奈良県新公会堂・東大寺総合文化センター（奈良県・奈良市）
- Year and Date
  2014-06-11 – 2014-06-13
- Data Source
  KAKENHI-PROJECT-26293066
[Presentation] 滑脳症発症に於けるLIS1-細胞質ダイニンの細胞内物流の役割　Intracellular logistics of LIS1-dynein in lissencephaly.
- Author(s)
  山田雅巳
- Organizer
  第87回日本生化学会年会
- Place of Presentation
  国立京都国際会館（京都府・京都市左京区）
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-26293066
[Presentation] 低分子量GTPase Rab6Aによる細胞質ダイニンの活性化メカニズムの解析
- Author(s)
  山田雅巳
- Organizer
  第35回日本分子生物学会
- Place of Presentation
  マリンメッセ福岡
- Data Source
  KAKENHI-PROJECT-22390056
[Presentation] ＬＩＳ１による細胞内ロジスティクスと滑脳症発症の関係
- Author(s)
  山田雅巳
- Organizer
  第4回新学術領域研究「細胞内ロジスティックス」班会議
- Place of Presentation
  仙台市太白区秋保町秋保温泉岩沼屋
- Data Source
  KAKENHI-PROJECT-22390056
[Presentation] Synucleins are essential for the creation of transportable microtubules, which is required for anterograde transport of cytoplasmic dynein.
- Author(s)
  Shiori Toba, Kotaro Koyasako, Masami Yamada, Takuo Yasunaga, Hiroaki Kojima, Hideki Wanibuchi, Shinji Hirotsune
- Organizer
  第52回日本生物物理学会年会
- Place of Presentation
  札幌コンベンションセンター（北海道・札幌市)
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26293066

1. SHIDA Hisatoshi (00144395)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. HAKATA Yoshiyuki (30344500)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. YASUDA Jiro (10282518)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. KATAOKA Yosuke (40291033)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. KIDOKORO Minoru (00370958)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. MORIYAMA Tetsuji (50627990)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. Jin Mingyue (60740404)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. HIROTSUNE Shinji (80337526)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. MATSUMOTO Sakiko (00789654)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. YASUNAGA Takuo (60251394)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. MIYADA Takaki (70311751)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. OIWA Kazuhiro (10211096)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. FURUTA Ken'ya (40571831)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. TOBA Shiori (40419891)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. Takahiro Yamauchi (50598670)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 藤田聡 (60504652)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. MIYAZAWA Atsuo

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. NAGAI Kakeharu

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. REVERSADE Bruno

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. POMP Oz

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 鰐渕英機

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yamada Masami 山田 雅巳

山田 雅巳 ヤマダ マサミ

YAMADA Masami 山田 雅巳

Research Projects

Research Products

Co-Researchers

Elucidation of the dynamics related to intracellular importin-alpha1 in the acceleration of migration of glioblastoma

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Drug screening for genetic diseases that occur in conjunction with neuronal migration disorders.Principal Investigator

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Clarify the pathogenic mechnism of microlissencephaly

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Intracellular logistics of LIS1-cytoplasmic dynein in lissencephaly.Principal Investigator

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ＬＩＳ１による細胞内ロジスティックスと滑脳症発症の関係Principal Investigator

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New strategy for lissencephaly therapeutic medicine development.Principal Investigator

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HIV/HTLV-1高感受性のヒトCRM1を発現するトランスジェニックラット

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Construction of a transgenic rat model, which is highly sensitive to HTLV-1 infection

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Cellular cofactors involved in transport of mRNAs of complex retroviruses and hepatitis B virus

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[Journal Article] 先天性神経疾患に対する新しい治療戦略2017

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[Journal Article] Alpha-synuclein facilitates to form short unconventional microtubules that have a unique function in the axonal transport2017

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[Journal Article] Alpha-synuclein binds unconventional microtubules that have a unique function.2017

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[Journal Article] 先天性神経疾患に対する新しい治療戦略2017

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[Journal Article] LIS1 の微小管モーター制御と滑脳症発症機構の解明2015

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Yamada Masami 山田雅巳

山田雅巳ヤマダマサミ

YAMADA Masami 山田雅巳