Matsubara Teruhiko 松原輝彦

… Alternative Names

MATSUBARA Teruhiko 松原輝彦

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Researcher Number	10325251
Other IDs
External Links
Affiliation (Current)	2025: 慶應義塾大学, 理工学部(矢上), 准教授
Affiliation (based on the past Project Information) *help	2023 – 2024: 慶應義塾大学, 理工学部(矢上), 准教授 2020 – 2021: 慶應義塾大学, 理工学部(矢上), 准教授 2016 – 2017: 慶應義塾大学, 理工学部(矢上), 講師 2011 – 2015: 慶應義塾大学, 理工学部, 講師 2010 – 2011: 慶応義塾大学, 理工学部, 講師 … More 2010 – 2011: 慶應義塾大学, 理工学部, 専任講師 2008: 慶應義塾大学, 理工学部, 講師 2006 – 2007: 慶應義塾大学, 理工学部, 助教 2003 – 2006: 慶應義塾大学, 理工学部, 助手 2002: 徳島大学, 工学部, 助手 Less
Review Section/Research Field	Principal Investigator Medium-sized Section 27:Chemical engineering and related fields / Transformative Research Areas, Section (II) / Biomolecular chemistry / Drug development chemistry / Chemistry related to living body / Bioorganic chemistry Except Principal Investigator Chemical biology / Nerve anatomy/Neuropathology / Biomedical engineering/Biological material science
Keywords	Principal Investigator ファージ提示法 / ペプチドライブラリー / バイオリアクター / ペプチド / ヘマグルチニン / インフルエンザ / ライブラリー / マイクロドメイン / 無容器 / 遺伝子導入 … More / 細胞培養 / 音響浮揚 / バイオ医薬品 / 化学修飾 / 中分子設計 / 人工ペプチド / 機械学習 / 生理活性 / ランダムライブラリー / ペプチド修飾 / 全方位非接触界面 / 音響放射圧 / 無容器反応 / 超音波 / 非接触界面 / 浮揚 / 音響波 / 定在波 / 難知性疾患 / 高感度検出 / 相互作用予測 / シアル酸 / 糖鎖 / インフルエンザウイルス / ペプチドリガンド / 感染阻害 / 膜融合 / 糖修飾ペプチド / 計算機シミュレーション / 糖鎖認識 / 相互作用解析 / 感染阻害機構 / ウイルス感染 / ヘマルチニン / ファージ / 感染症 / 親和性選択 / 感染阻害剤 / ペプチドドラッグ / ラフト / 糖鎖クラスター / 原子間力顕微鏡 / レクチン / スフィンゴ糖脂質 / ペプチドライブリー / 細胞内小胞 / セレクション / ファージディスプレイ法 / リポソーム / 脂質二重膜 / 生体膜 … More Except Principal Investigator 糖鎖 / 糖脂質 / インフルエンザウイルス / 糖鎖解析 / Oーグリカン / グリコサミノグリカン / O-グリカン / 転移性がん細胞 / オリゴ糖 / 腫瘍マーカー / ムコ多糖症 / 糖鎖ライブラリー / iPS細胞 / C型肝炎ウイルス / がん細胞 / 質量分析装置 / 糖鎖プライマー / 糖鎖工学 / グライコミクス / NMR / 質量分析 / 老人斑 / 認知症 / アミロイドベータ蛋白質 / アルツハイマー病 / 痴呆 / 蛋白質 / 神経変性疾患 / 進化分子工学 / 感染阻害剤 / 分子進化 / インフルエンザ / ガングリオシド / 分子進化工学 / バイオパニング / 感染阻害 / ペプチド / ファージライブラリー / ヘマグルチニン Less

Development of a highly efficient method of gene transfer into cells using acoustic levitationPrincipal Investigator
- Principal Investigator
  
  松原輝彦
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 27:Chemical engineering and related fields
- Research Institution
  Keio University
Development of target-oriented modification of peptide resources obtained by phage display methodPrincipal Investigator
- Principal Investigator
  
  松原輝彦
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (II)
- Research Institution
  Keio University
Development of innovative bioreactor having omnidirectional contactless interfacePrincipal Investigator
- Principal Investigator
  
  Matsubara Teruhiko
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 27:Chemical engineering and related fields
- Research Institution
  Keio University
Inhibition mechanism of modified peptide ligands that mimic complicated sugar receptorsPrincipal Investigator
- Principal Investigator
  
  Matsubara Teruhiko
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biomolecular chemistry
- Research Institution
  Keio University
Analysis and control of cell function based on novel glycomics using saccharide primer method
- Principal Investigator
  
  Sato Toshinori
- Project Period (FY)
  2011 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Chemical biology
- Research Institution
  Keio University
Study on molecular mechanism underlying brain region-specific Ass deposition
- Principal Investigator
  
  YANAGISAWA Katsuhiko
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  National Center for Geriatrics and Gerontology
Development of design of antiviral drug by substitution of carbohydrate ligand for peptidePrincipal Investigator
- Principal Investigator
  
  MATSUBARA Teruhiko
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Drug development chemistry
- Research Institution
  Keio University
Development of infection inhibitors using molecular evolutional phage library method
- Principal Investigator
  
  SATO Toshinori
- Project Period (FY)
  2005 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Keio University
糖鎖結合ペプチドによる糖脂質の集合/分散状態の識別手法の開発Principal Investigator
- Principal Investigator
  
  松原輝彦
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Chemistry related to living body
- Research Institution
  Keio University
脂質膜に自発的挿入するペプチド分子の動的高次構造と細胞内挙動の解析Principal Investigator
- Principal Investigator
  
  松原輝彦
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Bioorganic chemistry
- Research Institution
  Keio University
  The University of Tokushima

[Book] ペプチド医薬品のスクリーニング・安定化・製剤化技術2017
- Author(s)
  松原輝彦・佐藤智典
- Total Pages
  557
- Publisher
  技術情報協会
- Data Source
  KAKENHI-PROJECT-15K01806
[Book] 糖鎖認識ペプチドの開発と応用(第4章バイオ超分子, 第4節糖鎖の超分子化学),「超分子サイエンス&テクノロジー」国武豊喜監修2009
- Author(s)
  松原輝彦・佐藤智典
- Publisher
  NTS
- Data Source
  KAKENHI-PROJECT-17300159
[Book] ファージディスプレイ法,「分子間相互作用解析ハンドブック」, 礒辺俊明・中山敬一・伊藤隆司監修2007
- Author(s)
  松原輝彦・佐藤智典
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-17300159
[Journal Article] Prevention of amyloid β fibril deposition on the synaptic membrane in the precuneus by ganglioside nanocluster-targeting inhibitors2024
- Author(s)
  Miyamoto Erika、Hayashi Hideki、Murayama Shigeo、Yanagisawa Katsuhiko、Sato Toshinori、Matsubara Teruhiko
- Journal Title
  
  RSC Chemical Biology
  
  Volume: － Issue: 5 Pages: 459-466
- DOI
  10.1039/d4cb00038b
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22KJ2711, KAKENHI-PUBLICLY-23H04562
[Journal Article] Cyclization of Peptides Enhances the Inhibitory Activity against Ganglioside-Induced Aβ Fibril Formation2023
- Author(s)
  Miyamoto Erika、Sato Toshinori、Matsubara Teruhiko
- Journal Title
  
  ACS Chemical Neuroscience
  
  Volume: 14 Issue: 23 Pages: 4199-4207
- DOI
  10.1021/acschemneuro.3c00589
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22KJ2711, KAKENHI-PUBLICLY-23H04562
[Journal Article] 繊細な生体物質を触れずに操る無容器バイオフラスコ2021
- Author(s)
  松原輝彦
- Journal Title
  
  バイオインダストリー
  
  Volume: 38 Pages: 1-7
- Data Source
  KAKENHI-PROJECT-20K21113
[Journal Article] Containerless Bioorganic Reactions in a Floating Droplet by Levitation Technique Using an Ultrasonic Wave2020
- Author(s)
  Matsubara Teruhiko、Takemura Kenjiro
- Journal Title
  
  Advanced Science
  
  Volume: 8 Issue: 3 Pages: 2002780-2002780
- DOI
  10.1002/advs.202002780
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21113
[Journal Article] インフルエンザ発症初期におけるウイルスのダイヤモンド電極による検出2018
- Author(s)
  松原輝彦・佐藤智典
- Journal Title
  
  NEW DIAMOND
  
  Volume: 34 Pages: 30-33
- Data Source
  KAKENHI-PROJECT-15K01806
[Journal Article] Design of Glycopolymers Carrying Sialyl Oligosaccharides for Controlling the Interaction with the Influenza Virus2017
- Author(s)
  Nagao Masanori、Fujiwara Yurina、Matsubara Teruhiko、Hoshino Yu、Sato Toshinori、Miura Yoshiko
- Journal Title
  
  Biomacromolecules
  
  Volume: 18 Issue: 12 Pages: 4385-4392
- DOI
  10.1021/acs.biomac.7b01426
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H03818, KAKENHI-PROJECT-15K01806, KAKENHI-PROJECT-16K14007
[Journal Article] Heptapeptide ligands against receptor-binding sites of influenza hemagglutinin toward anti-influenza therapy2016
- Author(s)
  Teruhiko Matsubara, Ai Onishi, Daisuke Yamaguchi, Toshinori Sato
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 24 Issue: 5 Pages: 1106-1114
- DOI
  10.1016/j.bmc.2016.01.039
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K01806, KAKENHI-PROJECT-23241075, KAKENHI-PROJECT-26560245
[Journal Article] 糖鎖模倣ペプチドのインフルエンザヘマグルチニンに対する結合活性の多価効果2016
- Author(s)
  松原輝彦、大西愛、齋藤智美、山口大介、佐藤智典
- Journal Title
  
  高分子論文集
  
  Volume: 73 Pages: 62-68
- NAID
  130005120382
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23241075
[Journal Article] Multivalent effect in influenza hemagglutinin-binding activity of sugar-mimic peptide2016
- Author(s)
  Teruhiko MATSUBARA, Ai ONISHI, Tomomi SAITO, Daisuke YAMAGUCHI, and Toshinori SATO
- Journal Title
  
  Kobunshi Ronbunshu
  
  Volume: 73 Pages: 62-68
- NAID
  130005120382
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K01806
[Journal Article] Highly sensitive detection of influenza virus by boron-doped diamond electrode terminated with sialic acid-mimic peptide2016
- Author(s)
  Teruhiko Matsubara, Michiko Ujie, Takashi Yamamoto, Miku Akahori, Yasuaki Einaga, Toshinori Sato
- Journal Title
  
  Proc. Natl. Acad. Sci. U.S.A.
  
  Volume: 113 Issue: 32 Pages: 8981-8984
- DOI
  10.1073/pnas.1603609113
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K01806
[Journal Article] Imbalance in Fatty-Acid-chain length of gangliosides triggers Alzheimer amyloid deposition in the precuneus.2015
- Author(s)
  Oikawa N, Matsubara T, Fukuda R, Yasumori H, Hatsuta H, Murayama S, Sato T, Suzuki A, Yanagisawa K.
- Journal Title
  
  PLoS One
  
  Volume: 23 Issue: 3 Pages: e0121356-e0121356
- DOI
  10.1371/journal.pone.0121356
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24700371, KAKENHI-PROJECT-23241075
[Journal Article] Synthesis and influenza virus inhibitory activities of carbosilane dendrimers peripherally-functionalized with hemagglutinin-binding peptide2014
- Author(s)
  Ken Hatano, Teruhiko Matsubara, Yosuke Muramatsu, Masakazu Ezure, Tetsuo Koyama, Koji Matsuoka, Ryunosuke Kuriyama, Haruka Kori, Toshinori Sato
- Journal Title
  
  J. Med. Chem.
  
  Volume: 57 Issue: 20 Pages: 8332-8339
- DOI
  10.1021/jm5007676
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23241075
[Journal Article] Incorporation of glycosylated amino acid into protein by an in vitro translation system2013
- Author(s)
  Teruhiko Matsubara, Kazutoshi Iijimaa, Takayoshi Watanabe, Takahiro Hohsaka, Toshinori Sato
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 23 Pages: 5634-5636
- Data Source
  KAKENHI-PROJECT-23241075
[Journal Article] Density of GM1 in Nanoclusters Is a Critical Factor in the Formation of a Spherical Assembly of Amyloid β-Protein on Synaptic Plasma Membranes.2013
- Author(s)
  Teruhiko Matsubara, Kazutoshi Iijima, Naoki Yamamoto, Katsuhiko Yanagisawa, and Toshinori Sato
- Journal Title
  
  Langmuir
  
  Volume: 29(7) Issue: 7 Pages: 2258-2264
- DOI
  10.1021/la3038999
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300118, KAKENHI-PROJECT-23241075
[Journal Article] Carbohydrate recognition by pentadecapeptide ligands for a series of sialylated oligosaccharides, Bioorg.2012
- Author(s)
  Teruhiko Matsubara, Ai Onishi, and Toshinori Sato
- Journal Title
  
  Med. Chem.
  
  Volume: 20(21) Issue: 21 Pages: 6452-6458
- DOI
  10.1016/j.bmc.2012.08.025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300118
[Journal Article] Brain insulin resistance accelerates Ass fibrillogenesis by inducing GM1 ganglioside clustering in the presynaptic membranes2012
- Author(s)
  Yamamoto N, Matsubara T, Sobue K., et al
- Journal Title
  
  J.Neurochem.
  
  Volume: 121 Issue: 4 Pages: 619-628
- DOI
  10.1111/j.1471-4159.2012.07668.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300118, KAKENHI-PROJECT-24592311
[Journal Article] Dissociation of beta-amyloid from lipoprotein in cerebrospinal fluid from Alzheimer' s disease accelerates beta-amyloid-422011
- Author(s)
  Takamura A, Kawarabayashi T, Yokoseki T, Shibata M, Morishima-Kawashima M, Saito Y, Murayama S, Ihara Y, Abe K, Shoji M, Michikawa M, Matsubara E
- Journal Title
  
  assembly. Neurosci Res
  
  Volume: 89 Issue: 6 Pages: 815-821
- DOI
  10.1002/jnr.22615
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21500343, KAKENHI-PROJECT-21591069, KAKENHI-PROJECT-22300118, KAKENHI-PROJECT-23659450
[Journal Article] Sialic acid-mimic peptides as hemagglutinin inhibitors for anti-influenza therapy2010
- Author(s)
  Teruhiko Matsubara, Ai Onishi, Tomomi Saito, Aki Shimada, Hiroki Inoue, Takao Taki, Kyosuke Nagata, Yoshio Okahata, and Toshinori Sato
- Journal Title
  
  J. Med. Chem
  
  Volume: 53 Pages: 4441-4449
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790115
[Journal Article] Sialic acid-mimic peptides as hemagglutinin inhibitors foranti-influenza therapy2010
- Author(s)
  Teruhiko Matsubara, Ai Onishi, Tomomi Saito, Aki Shimada, Hiroki Inoue, Takao Taki, Kyosuke Nagata, Yoshio Okahata, Toshinori Sato
- Journal Title
  
  J.Med.Chem.
  
  Volume: 53 Pages: 4441-4449
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790115
[Journal Article] domain with a helix-loop-helix structure2008
- Author(s)
  T. Matsubara, M. Iida, T. Tsumuraya, I. Fujii, and T. Sato
- Journal Title
  
  Biochemistry 47
  
  Pages: 6745-6751
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17300159
[Journal Article] Selection of carbohydrate-binding domain with a helix-loop-helix structure2008
- Author(s)
  T. Matsubara, M. Iida, T. Tsumuraya, I. Fujii, T. Sato
- Journal Title
  
  Biochemistry 47(26)
  
  Pages: 6745-6751
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17300159
[Journal Article] Specific binding of GM1-binding peptides to high-density GM1 in lipid membranes2007
- Author(s)
  T. Matsubara, K. Iijima, M. Nakamura, T. Taki, Y. Okahata, and T. Sato
- Journal Title
  
  Langmuir 23
  
  Pages: 708-714
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17300159
[Journal Article] Identification of oligosaccharide-recognition molecules by phage-display technology2007
- Author(s)
  T. Matsubara, and T. Sato
- Journal Title
  
  Trends Glycosci. Glycotech. 19
  
  Pages: 133-145
- NAID
  10019855807
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17300159
[Journal Article] Structural Transition Study of a Fifteen Amino Acid Residue Peptide Induced by GM12007
- Author(s)
  N.Fujitani, H.Shimizu, T.Matsubara, T.Ohta, Y.Komata, N.Muira, T.Sato, and S.-I.Nishimura
- Journal Title
  
  Carbohydr.Res. 342
  
  Pages: 1895-1903
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17300159
[Journal Article] Identification of Oligosaccharide-Recognition Molecules by Phage-Display Technology2007
- Author(s)
  M.Matsubara, T.Sato
- Journal Title
  
  Trends In Glycoscience and Glycotechnology 19
  
  Pages: 133-145
- NAID
  10019855807
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17300159
[Journal Article] Specific binding of GM1-binding peptides to high-density GM1 in lipid membranes2007
- Author(s)
  T. Matsubara, K. Iijima, M. Nakamura, T. Taki, Y. Okahata, T. Sato
- Journal Title
  
  Langmuir 23
  
  Pages: 708-714
- Data Source
  KAKENHI-PROJECT-17300159
[Journal Article] Specific binding of GM1-binding peptides to high-density GM1 in lipid membranes2007
- Author(s)
  Teruhiko Matsubara, Kazutoshi Iijima, Miwa Nakamura, Takao Taki, Yoshio Okahata, Toshinori Sato
- Journal Title
  
  Langmuir 23 (2)
  
  Pages: 708-714
- Data Source
  KAKENHI-PROJECT-17750166
[Journal Article] Structural transition study of a fifteen amino acid residue peptide induced by GM12007
- Author(s)
  N. Fujitani, H. Shimizu, T. Matsubara, T. Ohta, Y. Komata, N. Muira, T. Sato, and S.-I. Nishimura
- Journal Title
  
  Carbohydr. Res. 342
  
  Pages: 1895-1903
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17300159
[Journal Article] 展開単分子膜を利用したオリゴ糖鎖結合性ペプチドの分子設計戦略2005
- Author(s)
  松原輝彦, 佐藤智典
- Journal Title
  
  高分子加工 54(6)
  
  Pages: 266-269
- NAID
  40006811915
- Data Source
  KAKENHI-PROJECT-17750166
[Patent] タンパク質又は病原体の新規検出方法2015
- Inventor(s)
  佐藤　智典・松原輝彦・栄長泰明・山本　崇史
- Industrial Property Rights Holder
  佐藤　智典・松原輝彦・栄長泰明・山本　崇史
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2015-093132
- Filing Date
  2015-04-30
- Overseas
- Data Source
  KAKENHI-PROJECT-23241075
[Patent] ンフルエンザ感染阻害ペプチド、インフルエンザウイルス感染阻害剤、リポソーム、インフルエンザ予防・治療剤2007
- Inventor(s)
  佐藤智典、松原輝彦
- Industrial Property Rights Holder
  慶應義塾大学
- Filing Date
  2007-03-07
- Overseas
- Data Source
  KAKENHI-PROJECT-17300159
[Patent] インフルエンザ感染阻害ペプチド、インフルエンザウイルス感染阻害剤、リポソーム、インフルエンザ予防・治療剤2007
- Inventor(s)
  佐藤智典, 松原輝彦
- Industrial Property Rights Holder
  慶應義塾大学
- Filing Date
  2007-03-07
- Data Source
  KAKENHI-PROJECT-17300159
[Patent] インフルエンザウイルス感染阻害方法2005
- Inventor(s)
  佐藤智典、松原輝彦
- Industrial Property Rights Holder
  株式会社グライコメディクス(慶應義塾大学より譲渡)
- Industrial Property Number
  2005-344531
- Filing Date
  2005-11-29
- Data Source
  KAKENHI-PROJECT-17300159
[Presentation] ファージ提示法で得られたペプチド配列リソースの標的指向型修飾法の開発2023
- Author(s)
  松原輝彦
- Organizer
  学術変革領域研究A予知生合成科学第2回公開シンポジウム
- Data Source
  KAKENHI-PUBLICLY-23H04562
[Presentation] Inhibition of Aβ Aggregation by Cyclic Peptides Targeting the GM1 Cluster on Lipid Membranes2023
- Author(s)
  Erika Miyamoto, Teruhiko Matsubara, Toshinori Sato
- Organizer
  International Symposium on Glycoconjugates (Glyco26)
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-23H04562
[Presentation] ガングリオシドGM1クラスターに結合するトリアゾール型環状ペプチドの開発2023
- Author(s)
  齊藤祐輝, 松原輝彦, 佐藤智典
- Organizer
  GlycoTOKYO 2023
- Data Source
  KAKENHI-PUBLICLY-23H04562
[Presentation] 糖修飾ペプチドによるインフルエンザウイルス感染阻害効果に対するメカニズム解析2023
- Author(s)
  横山大晟，松原輝彦, 佐藤智典
- Organizer
  GlycoTOKYO 2023
- Data Source
  KAKENHI-PUBLICLY-23H04562
[Presentation] 音響浮揚で生成した全方位非接触界面を持つ液滴内における生物有機化学反応2021
- Author(s)
  松原輝彦、竹村研治郎
- Organizer
  日本化学会第101春季年会(2021)
- Data Source
  KAKENHI-PROJECT-20K21113
[Presentation] 定在波トラッピングで作製した非接触液滴内における合成反応の追跡2021
- Author(s)
  松原輝彦・竹村研治郎
- Organizer
  第30回ソノケミストリー討論会
- Data Source
  KAKENHI-PROJECT-20K21113
[Presentation] 全方位非接触液滴による新規なバイオリアクターの開発2021
- Author(s)
  松原輝彦・吉田顕子・竹村研治郎・佐藤智典
- Organizer
  第31回バイオ・高分子シンポジウム
- Data Source
  KAKENHI-PROJECT-20K21113
[Presentation] Potential usage of acoustic levitation in phage-display technology2021
- Author(s)
  Akiko Yoshida・Teruhiko Matsubara・Toshinori Sato
- Organizer
  The 2021 International Chemical Congress of Pacific Basin Societies (Pacifichem 2021)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21113
[Presentation] インフルエンザウイルス感染を阻害する糖ペプチドの作用メカニズム2018
- Author(s)
  藤原由梨奈・松原輝彦・佐藤智典
- Organizer
  日本化学会第98春季年会
- Data Source
  KAKENHI-PROJECT-15K01806
[Presentation] The mechanism of Inhibition of Influenza Virus Infection by sugar-modified peptide2017
- Author(s)
  Yurina Fujiwara, Shunsuke Arami, Teruhiko Matsubara, Toshinori Sato
- Organizer
  第64回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-15K01806
[Presentation] Peptide-based biosensors: design and modification of receptor-mimic peptides for electrochemical detection of the influenza virus by a boron-doped diamond electrode2017
- Author(s)
  T. Matsubara
- Organizer
  2017 Fall Meeting of E-MRS
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K01806
[Presentation] シアル酸模倣ペプチドによるインフルエンザウイルス検出2017
- Author(s)
  松原輝彦
- Organizer
  6th Negative Strand Virus-Japan Symposium
- Place of Presentation
  ラグナガーデンホテル（沖縄県・宜野湾市）
- Year and Date
  2017-01-16
- Data Source
  KAKENHI-PROJECT-15K01806
[Presentation] Inhibition of lnfluenza Virus Infection by sugar-modified peptide2016
- Author(s)
  Yurina Fujiwara, Shunsuke Arami, Shoko Chiba, Teruhiko Matsubara, Toshinori Sato
- Organizer
  第64回日本ウイルス学会学術集会
- Place of Presentation
  札幌コンベンションセンター（北海道・札幌市）
- Year and Date
  2016-10-23
- Data Source
  KAKENHI-PROJECT-15K01806
[Presentation] ヘマグルチニンの受容体結合部位に挿入されるペプチドの計算機支援による設計2016
- Author(s)
  松原輝彦・大西愛・山口大介・佐藤智典
- Organizer
  第26回バイオ・高分子シンポジウム
- Place of Presentation
  東京工業大学（東京）
- Year and Date
  2016-07-28
- Data Source
  KAKENHI-PROJECT-15K01806
[Presentation] 糖鎖プライマー法で獲得したオリゴ糖を固定化した微粒子によるインフルエンザウイルスの検出2016
- Author(s)
  河野里砂、大上彩香、松原輝彦、佐藤智典
- Organizer
  日本化学会第９６春季年会
- Place of Presentation
  同志社大学（京都府・京田辺市）
- Year and Date
  2016-03-24
- Data Source
  KAKENHI-PROJECT-23241075
[Presentation] インフルエンザウイルスの感染を阻害する糖鎖模倣ペプチドの設計2016
- Author(s)
  松原輝彦
- Organizer
  5th Negative Strand Virus-Japan Symposium
- Place of Presentation
  ホテルモントレ沖縄（沖縄県・恩納村）
- Year and Date
  2016-01-25
- Data Source
  KAKENHI-PROJECT-15K01806
[Presentation] インフルエンザウイルス感染を阻害する糖ペプチドの開発2016
- Author(s)
  藤原由梨奈・荒見俊介・千葉頌子・松原輝彦・佐藤智典
- Organizer
  日本化学会第96春季年会
- Place of Presentation
  同志社大学（京都府・京田辺市）
- Year and Date
  2016-03-24
- Data Source
  KAKENHI-PROJECT-15K01806
[Presentation] Affinity selection of hemagglutinin-binding heptapeptide and in silico docking simulation2015
- Author(s)
  Teruhiko Matsubara, Ai Onishi, Daisuke Yamaguchi, Toshinori Sato
- Organizer
  THE INTERNATIONAL CHEMICAL CONGRESS OF PACIFIC BASIN SOCIETIES 2015
- Place of Presentation
  Honolulu (USA)
- Year and Date
  2015-12-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K01806
[Presentation] Intracellular protein delivery using ganglioside GM1-binding peptide2015
- Author(s)
  Haruka Maeno, Teruhiko Matsubara, ToshinoriSato
- Organizer
  Pacifichem 2015
- Place of Presentation
  ホノルル（米国）
- Year and Date
  2015-12-14
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23241075
[Presentation] 糖鎖プライマー法により得られたオリゴ糖を用いるインフルエンザウイルスの検出法の開発2015
- Author(s)
  佐藤　智典、大上彩香、松原輝彦
- Organizer
  日本糖質学会第３４回年会
- Place of Presentation
  東京大学（東京都・文京区）
- Year and Date
  2015-07-31
- Data Source
  KAKENHI-PROJECT-23241075
[Presentation] Intracellular delivery of proteins using ganglioside GM1-binding peptide2015
- Author(s)
  Haruka MAENO, Misato TOTSUKA, Teruhiko MATSUBARA, Toshinori SATO
- Organizer
  第64回高分子学会年次大会
- Place of Presentation
  札幌コンベンションセンター（札幌市・白石区）
- Year and Date
  2015-05-25
- Data Source
  KAKENHI-PROJECT-23241075
[Presentation] 糖鎖ミミックペプチドとヘマグルチニンとの相互作用の熱力学的考察2015
- Author(s)
  吉川栞・栗山龍之介・郡遥香・松原輝彦・佐藤智典
- Organizer
  第64回高分子年次大会
- Place of Presentation
  札幌コンベンションセンター（北海道・札幌市）
- Year and Date
  2015-05-27
- Data Source
  KAKENHI-PROJECT-15K01806
[Presentation] ガングリオシドGM1結合性ペプチドを用いたタンパク質の細胞内デリバリー2015
- Author(s)
  前野　陽香、戸塚　美里、松原輝彦、佐藤　智典
- Organizer
  第31回日本DDS学会
- Place of Presentation
  京王プラザホテル（東京都・新宿区）
- Year and Date
  2015-07-02
- Data Source
  KAKENHI-PROJECT-23241075
[Presentation] ペプチドアプタマーとインフルエンザヘマグルチニンとの相互作用解析2014
- Author(s)
  柴田ラビ、松原輝彦、佐藤智典
- Organizer
  第63 回高分子討論会
- Place of Presentation
  長崎大学（長崎県・長崎市）
- Year and Date
  2014-09-25
- Data Source
  KAKENHI-PROJECT-23241075
[Presentation] 糖鎖プライマー法で得られたオリゴ糖を用いたインフルエンザウイルス検出法の開発2014
- Author(s)
  大上彩香、久井智子、高橋良尚、郡遥香、松原輝彦、佐藤智典
- Organizer
  GlycoTOKYO2014シンポジウム
- Place of Presentation
  千葉大学（千葉県・松戸市）
- Year and Date
  2014-11-08
- Data Source
  KAKENHI-PROJECT-23241075
[Presentation] アミロイドベータの凝集機構の解明のためのGM1含有生体膜モデルの構築2012
- Author(s)
  福田竜統, 小島昂大, 松原輝彦, 山本直樹, 柳澤勝彦, 佐藤智典
- Organizer
  日本化学会第92春季年会(2012)
- Place of Presentation
  慶應義塾大学(横浜)
- Year and Date
  2012-03-25
- Data Source
  KAKENHI-PROJECT-22300118
[Presentation] 細胞膜界面における糖鎖ナノクラスター構築とペプチドによる糖鎖認識制御2011
- Author(s)
  松原輝彦
- Organizer
  第6回理研「バイオものづくり」シンポジウム
- Place of Presentation
  理化学研究所(和光市)
- Year and Date
  2011-05-10
- Data Source
  KAKENHI-PROJECT-22790115
[Presentation] インフルエンザウィルス結合性ペプチド担持カルボシランデンドリマーの合成2011
- Author(s)
  江連一正・小山哲夫・松岡浩司・松原輝彦・佐藤智典・幡野健
- Organizer
  第15回ケイ素化学協会シンポジウム
- Place of Presentation
  シーパル須磨(神戸市)
- Year and Date
  2011-10-21
- Data Source
  KAKENHI-PROJECT-22790115
[Presentation] GM1含有脂質膜におけるアミロイドベータの凝集機構の解析2011
- Author(s)
  小島昂大, 松原輝彦, 山本直樹, 柳澤勝彦, その他
- Organizer
  日本化学会第91春季年会
- Place of Presentation
  神奈川大学(神奈川県)
- Year and Date
  2011-03-15
- Data Source
  KAKENHI-PROJECT-22300118
[Presentation] 細胞膜界面における糖鎖ナノクラスター構築とペプチドによる糖鎖認識制御2011
- Author(s)
  松原輝彦
- Organizer
  第6回理研「バイオものづくり」シンポジウム
- Place of Presentation
  理化学研究所(和光市)(招待講演)
- Year and Date
  2011-05-10
- Data Source
  KAKENHI-PROJECT-22790115
[Presentation] 細胞膜界面における糖鎖ナノクラスター構築とペプチドによる糖鎖認識制御2011
- Author(s)
  松原輝彦
- Organizer
  第6回理研「バイオものづくり」シンポジウム
- Place of Presentation
  理化学研究所(和光市)(招待講演)
- Year and Date
  2011-05-10
- Data Source
  KAKENHI-PROJECT-22300118
[Presentation] 糖修飾ペプチドによるインフルエンザウイルスの感染阻害メカニズムの解析2011
- Author(s)
  荒見俊介, 松原輝彦, 佐藤智典
- Organizer
  日本化学会第91春季年会
- Place of Presentation
  神奈川大学(横浜)
- Year and Date
  2011-03-28
- Data Source
  KAKENHI-PROJECT-22790115
[Presentation] 糖鎖模倣ペプチドの多価によるウイルス感染への影響2011
- Author(s)
  松原輝彦・千葉頌子・荒見俊介・佐藤智典
- Organizer
  第60回(2011年)高分子討論会
- Place of Presentation
  岡山大学(岡山市)
- Year and Date
  2011-09-28
- Data Source
  KAKENHI-PROJECT-22790115
[Presentation] ヘマグルチニン結合性ペプチドの化学修飾によるウイルス感染阻害活性への効果2010
- Author(s)
  松原輝彦, 荒見俊介, 千葉頒子, 金子里枝子, 佐藤智典
- Organizer
  第4回バイオ関連化学シンポジウム
- Place of Presentation
  大阪大学(豊中)
- Year and Date
  2010-09-26
- Data Source
  KAKENHI-PROJECT-22790115
[Presentation] Design of sugar-mimicking peptide inhibitors on influenza virus infection2010
- Author(s)
  T.Matsubara ; T.Saito ; A.Shimada ; A.Onishi ; T.Sato
- Organizer
  2010 International Chemical Congress of Pacific Basin Societies (PACIFICHEM 2010)
- Place of Presentation
  ハワイコンベンションションセンター(ホノルル)
- Year and Date
  2010-12-16
- Data Source
  KAKENHI-PROJECT-22790115
[Presentation] ライブラリーを用いた糖鎖-タンパク質相互作用を制御するペプチドの設計2010
- Author(s)
  松原輝彦
- Organizer
  Glyco TOKYO 2010
- Place of Presentation
  東京大学(東京)
- Year and Date
  2010-11-27
- Data Source
  KAKENHI-PROJECT-22790115
[Presentation] スフィンゴ糖脂質の膜マイクロドメイン内分布と分子認識機構2010
- Author(s)
  松原輝彦, その他
- Organizer
  第59回高分子討論会
- Place of Presentation
  北海道大学(北海道)
- Year and Date
  2010-09-15
- Data Source
  KAKENHI-PROJECT-22300118
[Presentation] ライブラリーを用いた糖鎖-タンパク質相互作用を制御するペプチドの設計2010
- Author(s)
  松原輝彦
- Organizer
  GlycoTOKYO 2010
- Place of Presentation
  東京大学(東京)(招待講演)
- Year and Date
  2010-11-27
- Data Source
  KAKENHI-PROJECT-22790115
[Presentation] Design of sugar-mimicking peptide inhibitors on influenza virus infection2010
- Author(s)
  T. Matsubara ; T. Saito ; A. Shimada ; A. Onishi ; T. Sato
- Organizer
  2010 International Chemical Congress of Pacific Basin Societies(PACIFICHEM 2010)
- Place of Presentation
  ハワイコンベンションションセンター(ホノルル)
- Year and Date
  2010-12-16
- Data Source
  KAKENHI-PROJECT-22790115
[Presentation] Analysis of amyloid ss-assembly mechanism using lipid membrane containing GM12010
- Author(s)
  Kojima T, (Matsubara T), et al.
- Organizer
  2010 International Chemical Congress of Pacific Basin Societies(PACIFICHEM 2010)
- Place of Presentation
  Hawaii(U.S.A)
- Year and Date
  2010-12-16
- Data Source
  KAKENHI-PROJECT-22300118
[Presentation] Mechanism of inhibitory activity against influenza virus infection by saccharide-modified peptides2010
- Author(s)
  S.Arami ; S.Chiba ; T.Matsubara ; T.Sato
- Organizer
  2010 International Chemical Congress of Pacific Basin Societies (PACIFICHEM 2010)
- Place of Presentation
  ハワイコンベンションションセンター(ホノルル)
- Year and Date
  2010-12-16
- Data Source
  KAKENHI-PROJECT-22790115
[Presentation] ライブラリー選択法で得られた新規ペプチドによる細胞表面糖鎖の機能制御2009
- Author(s)
  松原輝彦
- Organizer
  日本化学会第89春季年会
- Place of Presentation
  日本大学理工学部船橋キャンパス
- Year and Date
  2009-03-28
- Data Source
  KAKENHI-PROJECT-17300159
[Presentation] インフルエンザウイルス感染阻害ペプチドの活性を向上する化学修飾2009
- Author(s)
  千葉頌子, 松原輝彦, 佐藤智典
- Organizer
  日本化学会第89春季年会
- Place of Presentation
  日本大学理工学部船橋キャンパス
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-17300159
[Presentation] インフルエンザウイルス感染を阻害するヘマグルチニン結合性ペンタペプチドの同定2008
- Author(s)
  齋藤智美・松原輝彦・佐藤智典
- Organizer
  第88回日本化学会年会
- Place of Presentation
  立教大学
- Year and Date
  2008-03-29
- Data Source
  KAKENHI-PROJECT-17300159
[Presentation] 細胞表面のシアル酸含有糖鎖を標的とするペプチドの設計および機能解析2008
- Author(s)
  松原輝彦・山下美季・野殿英恵・佐藤智典
- Organizer
  第57回高分子討論会
- Place of Presentation
  大阪市立大学
- Year and Date
  2008-09-24
- Data Source
  KAKENHI-PROJECT-17300159
[Presentation] 隠れマルコフモデルによるインフルエンザヘマグルチニン結合性ペンタデカペプチドの配列パターン解析2008
- Author(s)
  山口大介・島田亜紀・大西愛・松原輝彦・佐藤智典
- Organizer
  第88回日本化学会年会
- Place of Presentation
  立教大学
- Year and Date
  2008-03-29
- Data Source
  KAKENHI-PROJECT-17300159
[Presentation] ヘマグルチニン結合性ペプチドの改変および短鎖化によるインフルエンザウイルス感染阻害活性の向上2008
- Author(s)
  松原輝彦, 斎藤智美, 山口大介, 大西愛, 佐藤智典
- Organizer
  第18回バイオ・高分子シンポジウム
- Place of Presentation
  上智大学
- Year and Date
  2008-07-26
- Data Source
  KAKENHI-PROJECT-17300159
[Presentation] シアリルオリゴ糖結合性ペプチドのインフルエンザウイルス感染阻害活性2008
- Author(s)
  松原輝彦, 角真智子, 久保田博之, 佐藤智典
- Organizer
  第57回高分子学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2008-05-28
- Data Source
  KAKENHI-PROJECT-17300159
[Presentation] インフルエンザウイルス広域感染阻害を目指したペプチドのヘマグルチニンとの相互作用解析2007
- Author(s)
  齋藤智美・松原輝彦・佐藤智典
- Organizer
  第56回高分子学会年次大会
- Place of Presentation
  京都国際会議場
- Year and Date
  2007-05-29
- Data Source
  KAKENHI-PROJECT-17300159
[Presentation] 隠れマルコフモデルによるインフルエンザヘマグルチニン結合性ペンタデカペプチドの配列パターン解析2007
- Author(s)
  山口大介・島田亜紀・大西愛・松原輝彦・佐藤智典
- Organizer
  第56回高分子学会年次大会
- Place of Presentation
  京都国際会議場
- Year and Date
  2007-05-29
- Data Source
  KAKENHI-PROJECT-17300159
[Presentation] 糖鎖結合性ペプチドとB16細胞との相互作用の解析2007
- Author(s)
  山下美季、野殿英恵、松原輝彦、佐藤智典
- Organizer
  第56回高分子学会年次大会
- Place of Presentation
  京都国際会議場
- Year and Date
  2007-05-29
- Data Source
  KAKENHI-PROJECT-17300159
[Presentation] 糖鎖集合体を認識するペプチドの構造および機能解析2007
- Author(s)
  松原輝彦、飯島一智、久保田博之、藤谷直樹、清水弘樹、西村紳一郎、佐藤智典
- Organizer
  第17回バイオ・高分子シンポジウム
- Place of Presentation
  上智大学
- Year and Date
  2007-07-30
- Data Source
  KAKENHI-PROJECT-17300159
[Presentation] Identification of peptides that inhibit influenza virus infection2006
- Author(s)
  T. Matsubara, T. Sato
- Organizer
  ISBC2006
- Place of Presentation
  Kobe
- Year and Date
  2006-08-08
- Data Source
  KAKENHI-PROJECT-17300159
[Presentation] ライブラリー選択で得られたオリゴ糖鎖認識ペプチドの構造と機能2006
- Author(s)
  松原輝彦, 飯島一智, 角真智子, 佐藤智典
- Organizer
  第55回高分子討論会
- Place of Presentation
  富山大学
- Year and Date
  2006-09-20
- Data Source
  KAKENHI-PROJECT-17300159
[Presentation] Inhibition of Influenza Virus Infection by Sialylgalactose-binding Peptides Selected from a Phage-displayed Random Library2005
- Author(s)
  T. Matsubara, M. Sumi, T. Taki, and T. Sato
- Organizer
  The Pacifichem 2005 Congress
- Place of Presentation
  Honolulu
- Year and Date
  2005-12-19
- Data Source
  KAKENHI-PROJECT-17300159
[Presentation] 614 糖鎖プライマー法により得られたオリゴ糖とIFVヘマグルチニンとの相互作用解析
- Author(s)
  大上彩香，久井智子，高橋良尚，郡遥香，松原輝彦，佐藤智典
- Organizer
  第３２回日本糖質学会年会
- Place of Presentation
  大阪国際交流センター
- Data Source
  KAKENHI-PROJECT-23241075
[Presentation] アミロイドβ凝集に関わる神経細胞膜ガングリオシドナノクラスターの同定
- Author(s)
  松原輝彦
- Organizer
  第6回バイオ関連化学シンポジウム
- Place of Presentation
  札幌市
- Data Source
  KAKENHI-PROJECT-22300118
[Presentation] Analysis of the interaction between peptide aptamers and hemagglutinin
- Author(s)
  Rabi Shibata, Teruhiko Matsubara, Toshinori Sato
- Organizer
  SFG & JSCR 2014 Joint Annual Meeting
- Place of Presentation
  ホノルル（米国）
- Year and Date
  2014-11-16 – 2014-11-19
- Data Source
  KAKENHI-PROJECT-23241075
[Presentation] シナプトソーム膜類似の糖脂質ナノクラスターの構造とアミロイドβとの相互作用解析
- Author(s)
  松原輝彦
- Organizer
  日本化学会第93春季年会
- Place of Presentation
  草津市
- Data Source
  KAKENHI-PROJECT-22300118

1. SATO Toshinori (00162454)

# of Collaborated Projects: 2 results

# of Collaborated Products: 35 results
2. 竹村研治郎 (90348821)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
3. YANAGISAWA Katsuhiko (10230260)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
4. KATO Koichi (20211849)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. MURAYAMA Shigeo (50183653)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. YAMAMOTO Naoki (90393157)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
7. SAKAKIBARA Yasubumi (10287427)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. Fujimoto Junichiro (60175578)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. Umezawa Akihiro (70213486)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. SUZUKI Tetsuro (00250184)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. FUJIWARA Yurina

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
12. HOSHINO Yu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. HATSUTA Hiroyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 森島真帆

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 三浦佳子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Matsubara Teruhiko 松原 輝彦

MATSUBARA Teruhiko 松原 輝彦

Research Projects

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Development of a highly efficient method of gene transfer into cells using acoustic levitationPrincipal Investigator

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Development of target-oriented modification of peptide resources obtained by phage display methodPrincipal Investigator

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Development of innovative bioreactor having omnidirectional contactless interfacePrincipal Investigator

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Inhibition mechanism of modified peptide ligands that mimic complicated sugar receptorsPrincipal Investigator

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Analysis and control of cell function based on novel glycomics using saccharide primer method

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Study on molecular mechanism underlying brain region-specific Ass deposition

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Development of design of antiviral drug by substitution of carbohydrate ligand for peptidePrincipal Investigator

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Development of infection inhibitors using molecular evolutional phage library method

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糖鎖結合ペプチドによる糖脂質の集合/分散状態の識別手法の開発Principal Investigator

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脂質膜に自発的挿入するペプチド分子の動的高次構造と細胞内挙動の解析Principal Investigator

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[Book] ペプチド医薬品のスクリーニング・安定化・製剤化技術2017

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[Book] 糖鎖認識ペプチドの開発と応用(第4章バイオ超分子, 第4節糖鎖の超分子化学),「超分子サイエンス&テクノロジー」国武豊喜監修2009

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[Book] ファージディスプレイ法,「分子間相互作用解析ハンドブック」, 礒辺俊明・中山敬一・伊藤隆司監修2007

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[Journal Article] Prevention of amyloid β fibril deposition on the synaptic membrane in the precuneus by ganglioside nanocluster-targeting inhibitors2024

Author(s)

Matsubara Teruhiko 松原輝彦

MATSUBARA Teruhiko 松原輝彦