Nishiyama Akira 西山成

… Alternative Names

NISHIYAMA Akira 西山成

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Researcher Number	10325334
Other IDs
External Links
Affiliation (Current)	2025: 香川大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2018 – 2024: 香川大学, 医学部, 教授 2006 – 2016: Kagawa University, Faculty of medicine, Professor, 医学部, 教授 2014: 香川大学, 医学部・薬理学, 教授 2005: Kagawa University, Faculty of Medicine, Assistant, 医学部, 助手 2004: Kagawa University, Faculty of Medicine, Dept of Pharmacology, Assistant, 医学部, 助手 2003: KAGAWA UNIVERSITY(Faculty of Medicine), Department of Pharmacology, Assistant, 医学部, 助手 2001 – 2002: Kagawa Medical University, Department of Pharmacology, Assistant, 医学部, 助手
Review Section/Research Field	Principal Investigator General pharmacology / Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields / Basic Section 59040:Nutrition science and health science-related / General pharmacology / Studies on the Super-Aging Society / General pharmacology Except Principal Investigator Kidney internal medicine / General pharmacology / Basic Section 59040:Nutrition science and health science-related / Basic Section 53040:Nephrology-related … More / Basic Section 34020:Analytical chemistry-related / Basic Section 21030:Measurement engineering-related / Applied pharmacology / 応用薬理学・医療系薬学 / General pharmacology / Measurement engineering / Neurology / Emergency medicine Less
Keywords	Principal Investigator 老化 / 腎臓 / 夏眠 / 生体防御反応 / 腎臓病 / 生活習慣病 / ミネラロコルチコイド受容体 / 腎障害 / アルドステロン / 酸化ストレス … More / 夏眠様反応 / 個体老化 / 健康長寿 / サルコペニア / メタボリックシンドローム / レニン・アンジオテンシン系 / 交感神経 / 血圧 / インスリン抵抗性 / SGLT2 / 糖尿病 / 肥満 / アンジオテンシンII / 糖尿病性腎症 / 地球温暖化 / 生体防御 / 健康寿命 / 代謝変化 / 浸透圧 / メタボローム / 加齢疾患 / 脳心腎・代謝連関 / アンジオテンシノーゲン / 希少糖 / 細胞周期 / 宇宙空間 / イルカ / 体液変化 / 体液 / 尿素 / 代謝異常 / カタボリズム / 体液保持 / 生体老化 / 腎機能 / カタボリズム（異化） / 異化反応 / 生体適応能力 / 高血圧 / 臓器連関 / レニンアンジオテンシン系 / レニンアンジオテンシンアルドステロン系 / 循環器・高血圧 / 薬理学 / NADPHオキシダーゼ / Rhoキナーゼ / MAPキナーゼ / MR / アンジオテンシン変換酵素阻害剤 / アンジオテンシン変換酵素阻害薬 / AT_1受容体拮抗薬 / OLETFラット / NAD(P)Hオキシダーゼ / 糸球体血行動態 / II型糖尿病性腎症 / 腎輸入細動脈 / 一酸化窒素 / アデノシン / 活性酸素 / 腎輸入細動 / ATP / 尿細管糸球体フィードバック … More Except Principal Investigator ATP / 高血圧 / 酸化ストレス / アンジオテンシン / クロト / Adrenergic receptor / Hypertension / Afferent arteriole / 輸入細動脈 / 一酸化窒素 / アデノシン / 赤外分光 / ミトコンドリア / MAPキナーゼ / 活性酸素 / 腎不全 / 慢性腎不全 / 血圧 / 代謝 / 筋萎縮 / 老化 / 体液 / G-6-P / phosphoenolpyruvic acid / グルタミン / 乳酸 / 腎糖新生 / lactate / G6Pase / Glutamate / PEPCK / renal gluconeogenesis / Nrf2 / oxidative stress / ラマンイメージング / 分化誘導 / エリスロポエチン産生細胞 / 分化誘導過程 / iPS細胞 / ラマン分光法 / ラット / 高開口数レンズ / 反射防止コーティング / 非球面レンズ / 中赤外分光 / グルコース / マルチスリット / 空間的位相シフト干渉法 / 超音波定在波 / 血糖値 / 赤外分光法 / パラメトリック効果 / スマートトイレ / 非侵襲血糖値センサー / 定在波 / 超音波 / フーリエ分光法 / 中赤外分光法 / Angiotensin / 心肥大 / アドレナリン作用薬 / Suramin / P2 receptor / Dahl salt-sensitive rats / Nephropathy / Tubulo-glomerular feedback / P2受容体 / スラミン / ダール食塩感受性高血圧ラット / 腎微小循環 / 尿細管・糸球体フィードバック / Mitogen-activated protein kinase / Mitochondria / Ischemic-reperfudion injury / Superoxide / angiotensin / アドレナリン受容体 / 心筋虚血再環流障害 / Dahl salt sensitive rat / Microdialysis method / Adenosine / Efferent arteriole / CCD camera / Tubulo-glomerular feedback mechanism / Dahl食塩感受性高血圧ラット / ミクロダイアリィシス法 / 糸球体輸出細動脈 / 糸球体輸入細動脈 / CCDカメラ / 尿細管・糸球体フィードバック機構 / afferent arteriole / microdialvsis / nitric oxide / adenosine / renal interstitium / tubuloglomenilar feedback / renal autoregulation / アデノシンA1受容体拮抗薬 / 糸球体濾過量 / アデノシンA_1受容体拮抗薬 / サイクリックGMP / 腎血流量 / 腎微小透析 / ミクロダイアリイシス法 / 腎間質 / 尿細管糸球体フィードバック機構 / 自動性調節 / 上皮間葉化現象 / 高血圧自然発症ラット / ジンクフィンガーヌクレアーゼ / 補体 / 脂質代謝異常 / マクロファージ / MRP8 / TLR4 / 自然炎症 / 糖尿病性腎症 / renin-angiotensin-system (RAS) / 慢性腎臓病（CKD） / 急性腎障害（AKI） / RAS / 慢性腎臓病(CKD) / 急性腎障害(AKI) / ミッドカイン / 生体組織 / 断層像 / 無侵襲血糖値センサー / 医用計測 / ワンショット / 高時間分解能 / 空間的位相シフト / 位相シフト干渉 / 分光イメージング / フーリエ分光 / Angiotensin II / megalin / Megalin / AngiotensinII / 腎間質線維化 / ネフローゼ症候群 / 糸球体硬化症 / Magalin / ノックアウトマウス / ポドサイト / Angiotensinogen / AngiotensinⅡ / エンドトキシン / メタボリックシンドローム / 糖尿病 / アンジオテンシノゲン / バイオマーカー / レニン-アンジオテンシン系 / 慢性腎臓病 / エンドサイトーシス / 近位尿細管 / メガリン / 血管平滑筋 / 一酸化窒素合成酵素 / アンギオテンシンII / アンジオテンシン受容体拮抗薬 / 脳 / インテグリン / 細胞間基質 / アンジオテンシンII / 血液脳関門 / 脳・神経 / NDA(P)Hオキシダーゼ / RT-PCR / TBARS / p22phox / 血液透析 / 透析 / 遺伝子発現 / 白血球 / NAD(P)Hオキシダーゼ / 循環 / 調圧神経系 / 副交感神経活動 / 交感神経活動 / 自律神経活動 / 中心静脈圧 / 心拍数 / 頭部外傷 / 腎臓交感神経活動 / 低体温 Less

Elucidation of the mechanism of age-associated hypertension and muscle wasting: from the perspective of body water loss
- Principal Investigator
  
  北田研人
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Kagawa University
過酷環境における「夏眠様反応」による体液制御法の開発Principal Investigator
- Principal Investigator
  
  西山成
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
- Research Institution
  Kagawa University
The mechanisms for renal protection by klotho protein supplementation
- Principal Investigator
  
  竹中恒夫
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  International University of Health and Welfare
Glycobiology-based cellular slow cycling for the development of anti-ageing drugsPrincipal Investigator
- Principal Investigator
  
  Akira Nishiyama
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
- Research Institution
  Kagawa University
老化・加齢性疾患の予防に向けた「夏眠様反応」制御メカニズム解明のための基盤研究Principal Investigator
- Principal Investigator
  
  西山成
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Kagawa University
Role of Nrf2 in renal gluconeogenesis and clarification of the control mechanism
- Principal Investigator
  
  Ogawa Susumu
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Tohoku University
Establishment of the method for non-destructive and non-invasive monitoring of iPS cells developing into EPO producing cells using Raman spectroscopy
- Principal Investigator
  
  Ishigaki Mika
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 34020:Analytical chemistry-related
- Research Institution
  Shimane University
Research on renal protection by klotho protein supplementation
- Principal Investigator
  
  Takenaka Tsuneo
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  International University of Health and Welfare
Identification of aestivation-dependent longevity and its regulationPrincipal Investigator
- Principal Investigator
  
  Nishiyama Akira
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Studies on the Super-Aging Society
- Research Institution
  Kagawa University
Ultrasonic-assisted mid-infrared spectroscopic imaging for non-invasive blood glucose sensor
- Principal Investigator
  
  Ichiro ISHIMARU
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 21030:Measurement engineering-related
- Research Institution
  Kagawa University
Kidney-mediated aging processPrincipal Investigator
- Principal Investigator
  
  Nishiyama Akira
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Kagawa University
New therapeutic strategy for brain-cardiorenal-glucose metabolism syndrome: targeting on the sympathetic nervous system and SGLT2Principal Investigator
- Principal Investigator
  
  Nishiyama Akira
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Kagawa University
Role of complement 3 in the pathogenesis of hypertension
- Principal Investigator
  
  FUKUDA Noboru
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Nihon University
脳心腎連関の病態における腎内アンジオテンシノーゲンの役割Principal Investigator
- Principal Investigator
  
  西山成
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Research Field
  
  General pharmacology
- Research Institution
  Kagawa University
Possible mechanisms responsible for mineralocorticoid-induced renal injuryPrincipal Investigator
- Principal Investigator
  
  NISHIYAMA Akira
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Kagawa University
Novel mechanism of progression of diabetic nephropathy by hyperlipidemia: MRP8/TLR4 signaling
- Principal Investigator
  
  KUWABARA Takashige
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Kyoto University
Mechanisms of progression of chronic kidney disease
- Principal Investigator
  
  MATSUSAKA Taiji
- Project Period (FY)
  2010 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Tokai University
Study on One-shot Compact Fourier-Spectroscopy for Non-invasive Medical Measurement
- Principal Investigator
  
  ISHIMARU Ichiro
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Measurement engineering
- Research Institution
  Kagawa University
Establishment of a new disease concept "the kidney and lung correlation through RAS in a renal damage"
- Principal Investigator
  
  SATO Waichi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Nagoya University
Molecular mechanisms of proximal tubule cell endocytosis and its pathological roles in the development of chronic kidney disease
- Principal Investigator
  
  SAITO Akihiko
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Niigata University
Mechanisms responsible for mineralocorticoid receptor-dependent renal injuryPrincipal Investigator
- Principal Investigator
  
  NISHIYAMA Akira
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Kagawa University
Role of nitric oxide in reactive oxygen species-dependent intracellular signal transduction in cardiovascular tissue
- Principal Investigator
  
  KIMURA Shoji
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Kagawa University
The regulation mechanism of brain angiotensin II
- Principal Investigator
  
  HOSOMI Naohisa
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kagawa University
The role of oxidative stress induced by NAD(P)H oxidase of leukocyte on cardiovascular damages in chronic kidney disease
- Principal Investigator
  
  KIYOMOTO Hideyasu
- Project Period (FY)
  2005 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Kagawa University
腎不全進行におけるアルドステロンの役割と、その阻害による新しい治療戦略Principal Investigator
- Principal Investigator
  
  西山成
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General pharmacology
- Research Institution
  Kagawa University
Interaction between AT1 and β-adrenergic receptors affects redox-sensitive intracellular signal transduction in heart
- Principal Investigator
  
  KIMURA Shoji
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Kagawa University
New Treatment for Nephropathy with the Normalization of Tubulo-Glomerular Feedback Mechanisms
- Principal Investigator
  
  ABE Youichi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied pharmacology
- Research Institution
  Kagawa University
家兎頭部外傷モデルにおける低温暴露中の腎臓交感神経活動の変化とその機序解明
- Principal Investigator
  
  関啓輔
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Emergency medicine
- Research Institution
  Kagawa University
  香川大学(医学部)
II型糖尿病性腎症における腎微小循環異常とそれを標的とした新たなる治療戦略-アンジオテンシンIIと活性酸素の役割-Principal Investigator
- Principal Investigator
  
  西山成
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General pharmacology
- Research Institution
  Kagawa University
  香川大学(医学部)
Relationship between mitochondrial ATP sensitive potassium channels and reactive oxygen species in cardiovascular tissue.
- Principal Investigator
  
  KIMURA Shoji
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Kagawa University
  香川大学(医学部)
Elucidation of Tubulo-Glomerular Feedback Mechanisms
- Principal Investigator
  
  ABE Youichi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  KAGAWA UNIVERSITY(Faculty of Medicine)
糖尿病性腎症進展における尿細管糸球体フィードバック機構障害の関与Principal Investigator
- Principal Investigator
  
  西山成
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General pharmacology
- Research Institution
  香川医科大学
Autoregulatory mechanisms of renal blood flow-Selective responses of afferent arteriole to renal perfusion pressure
- Principal Investigator
  
  ABE Youichi
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Kagawa Medical University

[Book] カラー　新しい薬理学2018
- Author(s)
  石井邦明、西山　成
- Total Pages
  588
- Publisher
  西村書店
- ISBN
  9784890134854
- Data Source
  KAKENHI-PROJECT-18H03191
[Book] 腎疾患・透析最新の治療2011-20132011
- Author(s)
  西山成, 他
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-20590253
[Book] 原発性アルドステロン症診療マニュアル改訂第2版2011
- Author(s)
  西山成
- Publisher
  診断と治療社
- Data Source
  KAKENHI-PROJECT-20590253
[Book] D-allose suppresses development of hypertension in salt-loaded spontaneously hypertensive rats(RARE SUGARS II, Edited by Asada Y, Kawanami Y, Tajima S)2008
- Author(s)
  Zhang GX, Nagai Y, Fujisawa Y, Nishiyama A, Kimura S.
- Publisher
  Art-Printing Co. Ltd.
- Data Source
  KAKENHI-PROJECT-19590250
[Book] レニン・アンジオテンシン系の病態生理,腎臓.THE ARB2006
- Author(s)
  西山成, 安部陽一
- Total Pages
  485
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-17790171
[Journal Article] Potential Role of the Skin in Hypertension Risk Through Water Conservation2024
- Author(s)
  Kitada Kento、Nishiyama Akira
- Journal Title
  
  Hypertension
  
  Volume: 81 Issue: 3 Pages: 468-475
- DOI
  10.1161/hypertensionaha.123.20700
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K17685, KAKENHI-PROJECT-23K24771
[Journal Article] Revisiting blood pressure and body fluid status2023
- Author(s)
  Kitada Kento、Nishiyama Akira
- Journal Title
  
  Clinical Science
  
  Volume: 137 Issue: 9 Pages: 755-767
- DOI
  10.1042/cs20220500
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K17685, KAKENHI-PROJECT-23K24771
[Journal Article] The Renin-Angiotensin-Aldosterone System in Metabolic Diseases and Other Pathologies2023
- Author(s)
  Ortiz Rudy M.、Satou Ryousuke、Zhuo Jia L.、Nishiyama Akira
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 24 Issue: 8 Pages: 7413-7413
- DOI
  10.3390/ijms24087413
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24771
[Journal Article] Possible renoprotective mechanisms of SGLT2 inhibitors.2023
- Author(s)
  Akira Nishiyama, Kento Kitada
- Journal Title
  
  Frontiers in Medicine
  
  Volume: 10 Pages: 1115413-1115413
- DOI
  10.3389/fmed.2023.1115413
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K17685, KAKENHI-PROJECT-20K20664, KAKENHI-PROJECT-23K24771, KAKENHI-PROJECT-22K19712
[Journal Article] Simultaneous SGLT2 inhibition and caloric restriction improves insulin resistance and kidney function in OLETF rats2023
- Author(s)
  Cornejo Manuel A.、Jardines Eira、Nishiyama Akira、Nakano Daisuke、Ortiz Rudy M.
- Journal Title
  
  Molecular and Cellular Endocrinology
  
  Volume: 560 Pages: 111811-111811
- DOI
  10.1016/j.mce.2022.111811
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19712, KAKENHI-PROJECT-23K24771
[Journal Article] Possible contribution of phosphate to the pathogenesis of chronic kidney disease in dolphins.2023
- Author(s)
  Nourin Jahan, Hiroyuki Ohsaki, Kiyoko Kaneko, Asadur Rahman, Takeshi Nishiyama, Makoto Koizumi, Shuichiro Yamanaka, Kento Kitada, Yuki Sugiura, Kenji Matsui, Takashi Yokoo, Takayuki Hamano, Makoto Kuro-O, Takuya Itou, Miwa Suzuki, Keiichi Ueda, Akira Nishiyama
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 5161-5161
- DOI
  10.1038/s41598-023-32399-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11191, KAKENHI-PROJECT-20K20664, KAKENHI-PROJECT-22K07396, KAKENHI-PROJECT-22K19712
[Journal Article] Klotho supplementation reverses renal dysfunction and interstitial fibrosis in remnant kidney.2023
- Author(s)
  Takenaka Tsuneo、Hasan Arif、Marumo Takeshi、Inoue Tsutomu、Miyazaki Takashi、Suzuki Hiromichi、Kurosaki Yoshifumi、Ishii Naohito、Nishiyama Akira、Hayashi Matsuhiko
- Journal Title
  
  Kidney and Blood Pressure Research
  
  Volume: 1 Issue: 1 Pages: 1-1
- DOI
  10.1159/000530469
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08261, KAKENHI-PROJECT-21K07350, KAKENHI-PROJECT-23K07702, KAKENHI-PROJECT-20K08641, KAKENHI-PROJECT-22K19712, KAKENHI-PROJECT-23K24771
[Journal Article] Antiproliferative effects of D-allose associated with reduced cell division frequency in glioblastoma2023
- Author(s)
  Suzuki Kenta、Ogawa Daisuke、Kanda Takahiro、Fujimori Takeshi、Shibayama Yuki、Rahman Asadur、Ye Juanjuan、Ohsaki Hiroyuki、Akimitsu Kazuya、Izumori Ken、Tamiya Takashi、Nishiyama Akira、Miyake Keisuke
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 19515-19515
- DOI
  10.1038/s41598-023-46796-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07396, KAKENHI-PROJECT-21K09177, KAKENHI-PROJECT-22K19712, KAKENHI-PROJECT-22K20712
[Journal Article] Potential Impact of Non-Steroidal Mineralocorticoid Receptor Antagonists in Cardiovascular Disease2023
- Author(s)
  Rahman Asadur、Jahan Nourin、Rahman Md Tanvir、Nishiyama Akira
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 24 Issue: 3 Pages: 1922-1922
- DOI
  10.3390/ijms24031922
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K20664, KAKENHI-PROJECT-20K17585, KAKENHI-PROJECT-23K24771
[Journal Article] Possible organ-protective effects of renal denervation: insights from basic studies2023
- Author(s)
  Akumwami Steeve、Morishita Asahiro、Iradukunda Achille、Kobara Hideki、Nishiyama Akira
- Journal Title
  
  Hypertension Research
  
  Volume: 46 Issue: 12 Pages: 2661-2669
- DOI
  10.1038/s41440-023-01393-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K24771
[Journal Article] Blood pressure adaptation in vertebrates: comparative biology2022
- Author(s)
  Nishiyama Akira、Kitada Kento、Suzuki Miwa
- Journal Title
  
  Kidney International
  
  Volume: 102 Issue: 2 Pages: 242-247
- DOI
  10.1016/j.kint.2022.03.032
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K19712, KAKENHI-PROJECT-21K17685, KAKENHI-PROJECT-20K20664, KAKENHI-PROJECT-23K24771
[Journal Article] Association of Antihypertensive Effects of Esaxerenone with the Internal Sodium Balance in Dahl Salt-Sensitive Hypertensive Rats2022
- Author(s)
  Hattori Mai、Rahman Asadur、Kidoguchi Satoshi、Jahan Nourin、Fujisawa Yoshihide、Morisawa Norihiko、Ohsaki Hiroyuki、Kobara Hideki、Masaki Tsutomu、Hossain Akram、Steeve Akumwami、Nishiyama Akira
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 23 Issue: 16 Pages: 8915-8915
- DOI
  10.3390/ijms23168915
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07396, KAKENHI-PROJECT-22K19712, KAKENHI-PROJECT-23K24771
[Journal Article] Hepatocellular carcinoma induces body mass loss in parallel with osmolyte and water retention in rats2022
- Author(s)
  Kidoguchi Satoshi、Kitada Kento、Nakajima Kazuki、Nakano Daisuke、Ohsaki Hiroyuki、Kittikulsuth Wararat、Kobara Hideki、Masaki Tsutomu、Yokoo Takashi、Takahashi Kazuo、Titze Jens、Nishiyama Akira
- Journal Title
  
  Life Sciences
  
  Volume: 289 Pages: 120192-120192
- DOI
  10.1016/j.lfs.2021.120192
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08691, KAKENHI-PROJECT-19K08715, KAKENHI-PROJECT-20K22876, KAKENHI-PROJECT-21K08266, KAKENHI-PROJECT-20K20664, KAKENHI-PROJECT-21K17685, KAKENHI-PROJECT-21K15671
[Journal Article] Angiotensin receptor blockade with olmesartan alleviates brain pathology in obese <scp>OLETF</scp> rats2022
- Author(s)
  Rodriguez‐Ortiz Carlos J.、Thorwald Max A.、Rodriguez Ruben、Mejias‐Ortega Marina、Kieu Zanett、Maitra Neilabjo、Hawkins Charlesice、Valenzuela Joanna、Peng Marcus、Nishiyama Akira、Ortiz Rudy M.、Kitazawa Masashi
- Journal Title
  
  Clinical and Experimental Pharmacology and Physiology
  
  Volume: 50 Issue: 3 Pages: 228-237
- DOI
  10.1111/1440-1681.13738
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19712
[Journal Article] Tolvaptan induces body fluid loss and subsequent water conservation in normal rats2022
- Author(s)
  Kidoguchi Satoshi、Kitada Kento、Fujisawa Yoshihide、Nakano Daisuke、Yokoo Takashi、Titze Jens、Nishiyama Akira
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 149 Issue: 3 Pages: 115-123
- DOI
  10.1016/j.jphs.2022.04.008
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19712, KAKENHI-PROJECT-21K17685, KAKENHI-PROJECT-20K20664
[Journal Article] Exposing intracellular molecular changes during the differentiation of human-induced pluripotent stem cells into erythropoietin-producing cells using Raman spectroscopy and imaging2022
- Author(s)
  Ishigaki M, Hitomi H, Ozaki Y, Nishiyama A.
- Journal Title
  
  Sci Rep.
  
  Volume: 12 Issue: 1 Pages: 20454-20454
- DOI
  10.1038/s41598-022-24725-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08292, KAKENHI-PROJECT-22K19712, KAKENHI-PROJECT-20K05556
[Journal Article] Glucose Increases Hepatic Mitochondrial Antioxidant Enzyme Activities in Insulin Resistant Rats Following Chronic Angiotensin Receptor Blockade2022
- Author(s)
  Godoy-Lugo Jose A.、Thorwald Max A.、Mendez Dora A.、Rodriguez Ruben、Nakano Daisuke、Nishiyama Akira、Ortiz Rudy M.
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 23 Issue: 18 Pages: 10897-10897
- DOI
  10.3390/ijms231810897
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24771
[Journal Article] Improved lipogenesis gene expression in liver is associated with elevated plasma angiotensin 1-7 after AT1 receptor blockade in insulin-resistant OLETF rats2022
- Author(s)
  Godoy-Lugo Jose A.、Mendez Dora A.、Rodriguez Ruben、Nishiyama Akira、Nakano Daisuke、So?anez-Organis Jose G.、Ortiz Rudy M.
- Journal Title
  
  Molecular and Cellular Endocrinology
  
  Volume: 555 Pages: 111729-111729
- DOI
  10.1016/j.mce.2022.111729
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24771
[Journal Article] Contributions of renal water loss and skin water conservation to blood pressure elevation in spontaneously hypertensive rats2022
- Author(s)
  Ogura Takahiro、Kitada Kento、Morisawa Norihiko、Fujisawa Yoshihide、Kidoguchi Satoshi、Nakano Daisuke、Kobara Hideki、Masaki Tsutomu、Titze Jens、Nishiyama Akira
- Journal Title
  
  Hypertension Research
  
  Volume: 46 Issue: 1 Pages: 32-39
- DOI
  10.1038/s41440-022-01044-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19712, KAKENHI-PROJECT-21K17685, KAKENHI-PROJECT-20K20664, KAKENHI-PROJECT-23K24771
[Journal Article] Glucose emission spectra through mid-infrared passive spectroscopic imaging of the wrist for non-invasive glucose sensing2022
- Author(s)
  Kitazaki Tomoya、Morimoto Yusuke、Yamashita So、Anabuki Daichi、Tahara Shiori、Nishiyama Akira、Wada Kenji、Ishimaru Ichiro
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 20558-20558
- DOI
  10.1038/s41598-022-25161-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19712, KAKENHI-PROJECT-23K22771
[Journal Article] New Concept of Onco-Hypertension and Future Perspectives2021
- Author(s)
  Kidoguchi Satoshi、Sugano Naoki、Tokudome Gorou、Yokoo Takashi、Yano Yuichiro、Hatake Kiyohiko、Nishiyama Akira
- Journal Title
  
  Hypertension
  
  Volume: 77 Issue: 1 Pages: 16-27
- DOI
  10.1161/hypertensionaha.120.16044
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H03191
[Journal Article] Protease-Activated Receptor 1 Contributes to Microcirculation Failure and Tubular Damage in Renal Ischemia-Reperfusion Injury in Mice2021
- Author(s)
  Guan Yu、Nakano Daisuke、Li Lei、Zheng Haofeng、Nishiyama Akira、Tian Ye、Zhang Lei
- Journal Title
  
  BioMed Research International
  
  Volume: 2021 Issue: 1 Pages: 1-8
- DOI
  10.1155/2021/6665714
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03191
[Journal Article] Effects of molidustat, a hypoxia-inducible factor prolyl hydroxylase inhibitor, on sodium dynamics in hypertensive subtotally nephrectomized rats2021
- Author(s)
  Zhang Anqi、Nakano Daisuke、Morisawa Norihiko、Kitada Kento、Kittikulsuth Wararat、Rahman Asadur、Morikawa Takashi、Konishi Yoshio、Nishiyama Akira
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 146 Issue: 2 Pages: 98-104
- DOI
  10.1016/j.jphs.2021.03.007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K20664
[Journal Article] Klotho supplementation attenuates blood pressure and albuminuria in murine model of IgA nephropathy2021
- Author(s)
  Takenaka Tsuneo、Hasan Arif、Marumo Takeshi、Kobori Hiroyuki、Inoue Tsutomu、Miyazaki Takashi、Suzuki Hiromichi、Nishiyama Akira、Ishii Naohito、Hayashi Matsuhiko
- Journal Title
  
  Journal of Hypertension
  
  Volume: Publish Ahead of Print Issue: 8 Pages: 1-10
- DOI
  10.1097/hjh.0000000000002845
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08731, KAKENHI-PROJECT-20K08641, KAKENHI-PROJECT-18K07455, KAKENHI-PROJECT-21K07350
[Journal Article] Adaptive physiological water conservation explains hypertension and muscle catabolism in experimental chronic renal failure2021
- Author(s)
  Kovarik Johannes J.、Morisawa Norihiko、Wild Johannes、Marton Adriana、Takase‐Minegishi Kaoru、Minegishi Shintaro、Daub Steffen、Sands Jeff M.、Klein Janet D.、Bailey James L.、Kovalik Jean‐Paul、Rauh Manfred、Karbach Susanne、Hilgers Karl F.、Luft Friedrich、Nishiyama Akira、Nakano Daisuke、Kitada Kento、Titze Jens
- Journal Title
  
  Acta Physiologica
  
  Volume: 00 Issue: 1
- DOI
  10.1111/apha.13629
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K17124, KAKENHI-PROJECT-20K22876, KAKENHI-PROJECT-19K17889, KAKENHI-PROJECT-18H03191, KAKENHI-PROJECT-20K20664
[Journal Article] Sodium/glucose cotransporter 2 and renoprotection: From the perspective of energy regulation and water conservation.2021
- Author(s)
  Kento Kitada, Satoshi Kidoguchi, Daisuke Nakano, Akira Nishiyama.
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 147 Issue: 3 Pages: 245-250
- DOI
  10.1016/j.jphs.2021.07.006
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K22876, KAKENHI-PROJECT-18H03191, KAKENHI-PROJECT-20K20664, KAKENHI-PROJECT-21K17685
[Journal Article] Cardioprotective Effects of a Nonsteroidal Mineralocorticoid Receptor Blocker, Esaxerenone, in Dahl Salt-Sensitive Hypertensive Rats2021
- Author(s)
  Rahman Asadur、Sawano Tatsuya、Sen Anupoma、Hossain Akram、Jahan Nourin、Kobara Hideki、Masaki Tsutomu、Kosaka Shinji、Kitada Kento、Nakano Daisuke、Imamura Takeshi、Ohsaki Hiroyuki、Nishiyama Akira
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 4 Pages: 2069-2069
- DOI
  10.3390/ijms22042069
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K20664, KAKENHI-PROJECT-18H03191
[Journal Article] Renal NG2-expressing cells have a macrophage-like phenotype and facilitate renal recovery after ischemic injury2021
- Author(s)
  Kittikulsuth Wararat、Nakano Daisuke、Kitada Kento、Suzuki Norio、Yamamoto Masayuki、Nishiyama Akira
- Journal Title
  
  American Journal of Physiology-Renal Physiology
  
  Volume: 321 Issue: 2 Pages: F170-F178
- DOI
  10.1152/ajprenal.00011.2021
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K20664, KAKENHI-PROJECT-23K21372
[Journal Article] 】Identification of black microplastics using long-wavelength infrared hyperspectral imaging with imaging-type two-dimensional Fourier spectroscopy2021
- Author(s)
  Kosuke Nogo, Kou Ikejima, Wei Qi, Natsumi Kawashima, Tomoya Kitazaki, Satoru Adachi, Kenji Wada, Akira Nishiyama, Ichiro Ishimaru
- Journal Title
  
  Analytical Methods
  
  Volume: 13 Issue: 5 Pages: 647-659
- DOI
  10.1039/d0ay01738h
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H01452, KAKENHI-PROJECT-19H04283
[Journal Article] The angiotensin II receptor-neprilysin inhibitor LCZ696 attenuates the progression of proteinuria in type 2 diabetic rats2020
- Author(s)
  Rahman Asadur、Sherajee Shamshad J.、Rafiq Kazi、Kobara Hideki、Masaki Tsutomu、Nakano Daisuke、Morikawa Takashi、Konishi Yoshio、Imanishi Masahito、Nishiyama Akira
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 142 Issue: 3 Pages: 124-126
- DOI
  10.1016/j.jphs.2019.09.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H03191
[Journal Article] Aberrant (pro)renin receptor expression induces genomic instability in pancreatic ductal adenocarcinoma through upregulation of SMARCA5/SNF2H2020
- Author(s)
  Shibayama,Y., Takahashi, K., Yamaguchi, H., Yasuda, J., Yamazaki, D., Rahman, A., Fujimori, T., Fujisawa, Y., Takai, S., Furukawa, T., Nakagawa, T., Ohsaki, H., Kobara, H., Wong, J.H., Masaki, T., Yuzawa, Y., Kiyomoto, H., Yachida, S., Fujimoto, A., Nishiyama, A.
- Journal Title
  
  Communications Biology
  
  Volume: 3 Issue: 1 Pages: 724-724
- DOI
  10.1038/s42003-020-01434-x
- NAID
  130008001357
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07690, KAKENHI-PLANNED-18H05511, KAKENHI-PROJECT-18H03191, KAKENHI-PROJECT-19H03795, KAKENHI-PROJECT-17K07193
[Journal Article] Effects of an SGLT2 inhibitor on the salt sensitivity of blood pressure and sympathetic nerve activity in a nondiabetic rat model of chronic kidney disease2020
- Author(s)
  Wan Ningning、Fujisawa Yoshihide、Kobara Hideki、Masaki Tsutomu、Nakano Daisuke、Rahman Asadur、Nishiyama Akira
- Journal Title
  
  Hypertension Research
  
  Volume: - Issue: 6 Pages: 492-499
- DOI
  10.1038/s41440-020-0410-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H03191
[Journal Article] Esaxerenone, a novel nonsteroidal mineralocorticoid receptor blocker (MRB) in hypertension and chronic kidney disease2020
- Author(s)
  Wan Ningning、Rahman Asadur、Nishiyama Akira
- Journal Title
  
  Journal of Human Hypertension
  
  Volume: 35 Issue: 2 Pages: 148-156
- DOI
  10.1038/s41371-020-0377-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H03191
[Journal Article] Klotho supplementation ameliorates blood pressure and renal function in DBA/2-pcy mice, a model of polycystic kidney disease.2020
- Author(s)
  Takenaka T, Kobori H, Inoue T, Takashi Miyasaki T,Suzuki H, Nishiyama H, Ishii N, Hayashi M
- Journal Title
  
  Am J Physiol Renal Physiol
  
  Volume: 316 Issue: 3 Pages: F557-F564
- DOI
  10.1152/ajprenal.00299.2019
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07455, KAKENHI-PROJECT-20K08641
[Journal Article] Antiproliferative effects of monoclonal antibodies against (pro)renin receptor in pancreatic ductal adenocarcinoma2020
- Author(s)
  Asadur Rahman , Makoto Matsuyama , Akio Ebihara , Yuki Shibayama , Arif Ul Hasan , Hironori Nakagami , Fumiaki Suzuki , Jiao Sun , Tomoe Kobayashi , Hiroki Hayashi , Daisuke Nakano , Hideki Kobara , Tsutomu Masaki , Akira Nishiyama
- Journal Title
  
  Molecular Cancer Therapeutics
  
  Volume: 19 Issue: 9 Pages: 1844-1845
- DOI
  10.1158/1535-7163.mct-19-0228
- NAID
  130007811853
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07690, KAKENHI-PROJECT-18H03191
[Journal Article] Partial Body Mass Recovery After Caloric Restriction Abolishes Improved Glucose Tolerance in Obese, Insulin Resistant Rats2020
- Author(s)
  Cornejo Manuel A.、Nguyen Julie、Cazares Joshua、Escobedo Benny、Nishiyama Akira、Nakano Daisuke、Ortiz Rudy M.
- Journal Title
  
  Frontiers in Endocrinology
  
  Volume: 11 Pages: 363-363
- DOI
  10.3389/fendo.2020.00363
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03191
[Journal Article] Effects of post-renal anemia treatment with the HIF-PHD inhibitor molidustat on adenine-induced renal anemia and kidney disease in mice2020
- Author(s)
  Li Lei、Nakano Daisuke、Zhang Anqi、Kittikulsuth Wararat、Morisawa Norihiko、Ohsaki Hiroyuki、Suzuki Norio、Yamamoto Masayuki、Nishiyama Akira
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 144 Issue: 4 Pages: 229-236
- DOI
  10.1016/j.jphs.2020.09.004
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H05649, KAKENHI-PROJECT-18H03191
[Journal Article] Organ protection by SGLT2 inhibitors: role of metabolic energy and water conservation2020
- Author(s)
  Marton Adriana、Kaneko Tatsuroh、Kovalik Jean-Paul、Yasui Atsutaka、Nishiyama Akira、Kitada Kento、Titze Jens
- Journal Title
  
  Nature Reviews Nephrology
  
  Volume: 17 Issue: 1 Pages: 65-77
- DOI
  10.1038/s41581-020-00350-x
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K20664, KAKENHI-PROJECT-18H03191
[Journal Article] Lipopolysaccharide induces filtrate leakage from renal tubular lumina into the interstitial space via a proximal tubular Toll-like receptor 4?dependent pathway and limits sensitivity to fluid therapy in mice2020
- Author(s)
  Nakano Daisuke、Kitada Kento、Wan Ningning、Zhang Yahua、Wiig Helge、Wararat Kittikulsuth、Yanagita Motoko、Lee Syann、Jia Lin、Titze Jens M.、Nishiyama Akira
- Journal Title
  
  Kidney International
  
  Volume: 97 Issue: 5 Pages: 904-912
- DOI
  10.1016/j.kint.2019.11.024
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03191
[Journal Article] Association of a Disrupted Dipping Pattern of Blood Pressure with Progression of Renal Injury during the Development of Salt-Dependent Hypertension in Rats2020
- Author(s)
  Sufiun Abu、Rahman Asadur、Rafiq Kazi、Fujisawa Yoshihide、Nakano Daisuke、Kobara Hideki、Masaki Tsutomu、Nishiyama Akira
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 21 Issue: 6 Pages: 2248-2248
- DOI
  10.3390/ijms21062248
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H03191
[Journal Article] Renal sympathetic nerve activity regulates cardiovascular energy expenditure in rats fed high salt2020
- Author(s)
  Morisawa N, Kitada K, Fujisawa Y, Nakano D, Yamazaki D, Kobuchi S, Li L, Zhang Y, Morikawa T, Konishi Y, Yokoo T, Luft FC, Titze J, Nishiyama A.
- Journal Title
  
  Hypertension research
  
  Volume: Epub Issue: 6 Pages: 482-491
- DOI
  10.1038/s41440-019-0389-1
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16003, KAKENHI-PROJECT-18H03191
[Journal Article] Simultaneous angiotensin receptor blockade and glucagon‐like peptide‐1 receptor activation ameliorate albuminuria in obese insulin‐resistant rats2019
- Author(s)
  Rodriguez Ruben、Escobedo Benny、Lee Andrew Y.、Thorwald Max、Godoy‐Lugo Jose A.、Nakano Daisuke、Nishiyama Akira、Parkes David G.、Ortiz Rudy M.
- Journal Title
  
  Clinical and Experimental Pharmacology and Physiology
  
  Volume: 47 Issue: 3 Pages: 422-431
- DOI
  10.1111/1440-1681.13206
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03191
[Journal Article] Nrf2-related gene expression is impaired during a glucose challenge in type II diabetic rat hearts2019
- Author(s)
  Thorwald Max A.、Godoy-Lugo Jose A.、Rodriguez Gema J.、Rodriguez Marco Antonio、Jamal Mostofa、Kinoshita Hiroshi、Nakano Daisuke、Nishiyama Akira、Forman Henry J.、Ortiz Rudy M.
- Journal Title
  
  Free Radical Biology and Medicine
  
  Volume: 130 Pages: 306-317
- DOI
  10.1016/j.freeradbiomed.2018.10.405
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03191
[Journal Article] Parametric standing wave generation of a shallow reflection plane in a nonrigid sample for use in a noninvasive blood glucose monitor2019
- Author(s)
  Tomoya Kitazaki; Natsumi Kawashima; Naoyuki Yamamoto; Hiroyuki Nomura; Hanyue Kang; Akira Nishiyama; Kenji Wada; Ichiro Ishimaru
- Journal Title
  
  Journal of Biomedical Optics
  
  Volume: 24(3) Issue: 03 Pages: 1-1
- DOI
  10.1117/1.jbo.24.3.036003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H01452, KAKENHI-PROJECT-18J22468
[Journal Article] A mouse model of renal fibrosis to overcome the technical variability in ischaemia/reperfusion injury among operators2019
- Author(s)
  Guan Yu、Nakano Daisuke、Zhang Yifan、Li Lei、Tian Ye、Nishiyama Akira
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 10435-10435
- DOI
  10.1038/s41598-019-46994-z
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03191
[Journal Article] Effect of a novel nonsteroidal selective mineralocorticoid receptor antagonist, esaxerenone (CS-3150), on blood pressure and renal injury in high salt-treated type 2 diabetic mice2019
- Author(s)
  Bhuiyan Abdus Sattar、Rafiq Kazi、Kobara Hideki、Masaki Tsutomu、Nakano Daisuke、Nishiyama Akira
- Journal Title
  
  Hypertension Research
  
  Volume: 42 Issue: 6 Pages: 892-902
- DOI
  10.1038/s41440-019-0211-0
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03191
[Journal Article] Effects of the novel nonsteroidal mineralocorticoid receptor blocker, esaxerenone (CS-3150), on blood pressure and urinary angiotensinogen in low-renin Dahl salt-sensitive hypertensive rats2019
- Author(s)
  Li Lei、Guan Yu、Kobori Hiroyuki、Morishita Asahiro、Kobara Hideki、Masaki Tsutomu、Nakano Daisuke、Nishiyama Akira
- Journal Title
  
  Hypertension Research
  
  Volume: 42 Issue: 6 Pages: 769-778
- DOI
  10.1038/s41440-018-0187-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H03191
[Journal Article] Diuretic Effects of Sodium Glucose Cotransporter 2 Inhibitors and Their Influence on the Renin-Angiotensin System2019
- Author(s)
  Ansary Tuba M.、Nakano Daisuke、Nishiyama Akira
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 20 Issue: 3 Pages: 629-629
- DOI
  10.3390/ijms20030629
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06893, KAKENHI-PROJECT-18H03191
[Journal Article] The Effects of Sodium-Glucose Cotransporter 2 Inhibitors on Sympathetic Nervous Activity.2018
- Author(s)
  Wan N, Rahman A, Hitomi H, Nishiyama A.
- Journal Title
  
  Front Endocrinol
  
  Volume: 26 Pages: 421-421
- DOI
  10.3389/fendo.2018.00421
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08246, KAKENHI-PROJECT-18H03191
[Journal Article] Pathophysiological mechanisms of mineralocorticoid receptor-dependent cardiovascular and chronic kidney disease2018
- Author(s)
  Nishiyama Akira
- Journal Title
  
  Hypertension Research
  
  Volume: 42 Issue: 3 Pages: 293-300
- DOI
  10.1038/s41440-018-0158-6
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03191
[Journal Article] Guanylyl cyclase A in both renal proximal tubular and vascular endothelial cells protects the kidney against acute injury in rodent experimental endotoxemia models.2018
- Author(s)
  Kidney against Acute Injury in Rodent Experimental Endotoxemia Models. Kitamura H, Nakano D, Sawanobori Y, Asaga T, Yokoi H, Yanagita M, Mukoyama M, Tokudome T, Kangawa K, Shirakami G, Nishiyama A.
- Journal Title
  
  Anesthesiology
  
  Volume: 印刷中 Issue: 2 Pages: 296-310
- DOI
  10.1097/aln.0000000000002214
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15KK0346, KAKENHI-PROJECT-17K09697, KAKENHI-PROJECT-17K09706, KAKENHI-PROJECT-17K09897, KAKENHI-PUBLICLY-18H04673, KAKENHI-PROJECT-18H03191, KAKENHI-PROJECT-17K19677
[Journal Article] Simultaneous GLP-1 receptor activation and angiotensin receptor blockade increase natriuresis independent of altered arterial pressure in obese OLETF rats2018
- Author(s)
  Rodriguez Ruben、Moreno Meagan、Lee Andrew Y.、Godoy-Lugo Jose A.、Nakano Daisuke、Nishiyama Akira、Parkes David、Awayda Mouhamed S.、Ortiz Rudy M.
- Journal Title
  
  Hypertension Research
  
  Volume: 41 Issue: 10 Pages: 798-808
- DOI
  10.1038/s41440-018-0070-0
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03191
[Journal Article] Chronic AT1 blockade improves glucose homeostasis in obese OLETF rats2018
- Author(s)
  Rodriguez Ruben、Minas Jacqueline N、Vazquez-Medina Jose Pablo、Nakano Daisuke、Parkes David G、Nishiyama Akira、Ortiz Rudy M
- Journal Title
  
  Journal of Endocrinology
  
  Volume: 237 Issue: 3 Pages: 271-284
- DOI
  10.1530/joe-17-0678
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03191
[Journal Article] A novel approach to adenine-induced chronic kidney disease associated anemia in rodents.2018
- Author(s)
  Rahman A, Yamazaki D, Sufiun A, Kitada K, Hitomi H, Nakano D, Nishiyama A.
- Journal Title
  
  PLoS One
  
  Volume: 13 Issue: 2 Pages: e0192531-e0192531
- DOI
  10.1371/journal.pone.0192531
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08246, KAKENHI-PROJECT-18H03191
[Journal Article] Independent regulation of renin?angiotensin?aldosterone system in the kidney2018
- Author(s)
  Nishiyama Akira、Kobori Hiroyuki
- Journal Title
  
  Clinical and Experimental Nephrology
  
  Volume: 22 Issue: 6 Pages: 1231-1239
- DOI
  10.1007/s10157-018-1567-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03191
[Journal Article] Effects of the selective chymase inhibitor TEI-F00806 on the intrarenal renin-angiotensin system in salt-treated angiotensin I-infused hypertensive mice2018
- Author(s)
  Ansary Tuba M.、Urushihara Maki、Fujisawa Yoshihide、Nagata Sayaka、Urata Hidenori、Nakano Daisuke、Hirofumi Hitomi、Kitamura Kazuo、Kagami Shoji、Nishiyama Akira
- Journal Title
  
  Experimental Physiology
  
  Volume: 103 Issue: 11 Pages: 1524-1531
- DOI
  10.1113/ep087209
- NAID
  130007900469
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03191, KAKENHI-PROJECT-16K19413
[Journal Article] Effects of an SGLT2 inhibitor on the systemic and intrarenal renin-angiotensin system in subtotally nephrectomized rats.2018
- Author(s)
  Li L, Konishi Y, Morikawa T, Zhang Y, Kitabayashi C, Kobara H, Masaki T, Nakano D, Hitomi H, Kobori H, Nishiyama A.
- Journal Title
  
  J. Pharmacol. Sci.
  
  Volume: 137 Issue: 2 Pages: 220-223
- DOI
  10.1016/j.jphs.2017.10.006
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08246, KAKENHI-PROJECT-18H03191
[Journal Article] Angiotensin receptor and tumor necrosis factor-α activation contributes to glucose intolerance independent of systolic blood pressure in obese rats2018
- Author(s)
  Rodriguez Ruben、Lee Andrew、Mathis Keisa W.、Broome Hanna J.、Thorwald Max、Martinez Bridget、Nakano Daisuke、Nishiyama Akira、Ryan Michael J.、Ortiz Rudy M.
- Journal Title
  
  American Journal of Physiology-Renal Physiology
  
  Volume: 315 Issue: 4 Pages: F1081-F1090
- DOI
  10.1152/ajprenal.00156.2018
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03191
[Journal Article] Ultrasonic standing wave preparation of a liquid cell for glucose measurements in urine by midinfrared spectroscopy and potential application to smart toilets2018
- Author(s)
  Naoyuki Yamamoto Natsumi Kawashima Tomoya Kitazaki Keita Mori Hanyue Kang Akira Nishiyama Kenji Wada Ichiro Ishimaru
- Journal Title
  
  Journal of Biomedical Optics
  
  Volume: 23(5) Issue: 05 Pages: 1-1
- DOI
  10.1117/1.jbo.23.5.050503
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H01452, KAKENHI-PROJECT-18J22468
[Journal Article] A sodium-glucose cotransporter 2 inhibitor attenuates renal capillary injury and fibrosis by a vascular endothelial growth factor-dependent pathway after renal injury in mice.2018
- Author(s)
  Zhang Y, Nakano D, Guan Y, Hitomi H, Uemura A, Masaki T, Kobara H, Sugaya T, Nishiyama A.
- Journal Title
  
  Kidney Int
  
  Volume: 94 Issue: 3 Pages: 524-535
- DOI
  10.1016/j.kint.2018.05.002
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08246, KAKENHI-PROJECT-18H03191, KAKENHI-PROJECT-16H06276
[Journal Article] Effect of a selective SGLT2 inhibitor, luseogliflozin, on circadian rhythm of sympathetic nervous function and locomotor activities in metabolic syndrome rats.2017
- Author(s)
  Rahman A, Fujisawa Y, Nakano D, Hitomi H, Nishiyama A.
- Journal Title
  
  Clin Exp Pharmacol Physiol.
  
  Volume: 44(4) Issue: 4 Pages: 522-525
- DOI
  10.1111/1440-1681.12725
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460343, KAKENHI-PROJECT-15K09266
[Journal Article] A sodium-glucose co-transporter 2 inhibitor empagliflozin prevents abnormality of circadian rhythm of blood pressure in salt-treated obese rats.2016
- Author(s)
  Takeshige Y, Fujisawa Y, Rahman A, Kittkulsuth W, Nakano D, Mori H, Masaki T, Ohmori K, Kohno M, Ogata H, Nishiyama A.
- Journal Title
  
  Hypertens. Res.
  
  Volume: 39(6) Issue: 6 Pages: 415-422
- DOI
  10.1038/hr.2016.2
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460343
[Journal Article] Effects of diuretics on sodium-dependent glucose cotransporter 2 inhibitor-induced changes in blood pressure in obese rats suffering from the metabolic syndrome.2016
- Author(s)
  Rahman A, Kittikulsuth W, Fujisawa Y, Sufiun A, Rafiq K, Hitomi H, Nakano D, Sohara E, Uchida S, Nishiyama A.
- Journal Title
  
  J Hypertens.
  
  Volume: 34 Issue: 5 Pages: 893-906
- DOI
  10.1097/hjh.0000000000000871
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05314, KAKENHI-PROJECT-26460343, KAKENHI-PROJECT-15K09266
[Journal Article] Unilateral ureteral obstruction attenuates intrarenal angiotensin Ⅱgeneration induced by podocyte injury.2015
- Author(s)
  Okabe M,Miyazaki Y,Niimura F,Pastan I,Nishiyama A,Yokoo T,Ichikawa I,Matsusaka T.
- Journal Title
  
  Am J Physiol Renal Physiol
  
  Volume: 308・8 Issue: 8 Pages: F932-F937
- DOI
  10.1152/ajprenal.00444.2014
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-22249033, KAKENHI-PROJECT-23249047, KAKENHI-PROJECT-26461241
[Journal Article] Effect of dipeptidyl peptidase-4 inhibition on circadian blood pressure during the development of salt-dependent hypertension in rats.2015
- Author(s)
  Sufiun A, Rafiq K, Fujisawa Y, Rahman A, Mori H, Nakano D, Kobori H, Ohmori K, Masaki T, Kohno M, Nishiyama A.
- Journal Title
  
  Hypertens Res.
  
  Volume: 38(4) Issue: 4 Pages: 237-243
- DOI
  10.1038/hr.2014.173
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460343
[Journal Article] Role of the renal sympathetic nerve in renal glucose metabolism during the development of type 2 diabetes in rats.2015
- Author(s)
  Rafiq K, Fujisawa Y, Sherajee SJ, Rahman A, Sufiun A, Kobori H, Koepsell H, Mogi M, Horiuchi M, Nishiyama A.
- Journal Title
  
  Diabetologia.
  
  Volume: 58(12) Issue: 12 Pages: 2885-2898
- DOI
  10.1007/s00125-015-3771-9
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460343
[Journal Article] Regression of glomerular and tubulointerstitial injuries by dietary salt reduction with combination therapy of angiotensin II receptor blocker and calcium channel blocker in Dahl salt-sensitive rats.2014
- Author(s)
  Rafiq K, Nishiyama A, Konishi Y, Morikawa T, Kitabayashi C, Kohno M, Masaki T, Mori H, Kobori H, Imanishi M.
- Journal Title
  
  PLoS One.
  
  Volume: 9(9) Issue: 9 Pages: e107853-e107853
- DOI
  10.1371/journal.pone.0107853
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-12F02420
[Journal Article] High sodium augments angiotensin II-induced vascular smooth muscle cell proliferation through the ERK 1/2-dependent pathway.2014
- Author(s)
  Liu G, Hitomi H, Rahman A, Nakano D, Mori H, Masaki T, Ma H, Iwamoto T, Kobori H, Nishiyama A.
- Journal Title
  
  Hypertens Res.
  
  Volume: 37(1) Issue: 1 Pages: 13-8
- DOI
  10.1038/hr.2013.108
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590303, KAKENHI-PROJECT-24591204
[Journal Article] Aldosterone aggravates glucose intolerance induced by high fructose2013
- Author(s)
  Sherajee SJ, Rafiq K, Nakano D, Mori H, Kobara H, Hitomi H, Fujisawa Y, Kobori H, Masaki T, Nishiyama A
- Journal Title
  
  Eur J Pharmacol
  
  Volume: 720 Pages: 63-68
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590303
[Journal Article] Calcium channel blocker enhances beneficial effects of an angiotensin II AT1 receptor blocker against cerebrovascular-renal injury in type 2 diabetic mice.2013
- Author(s)
  Rafiq K, Sherajee SJ, Hitomi H, Nakano D, Kobori H, Ohmori K, Mori H, Kobara H, Masaki T, Kohno M, Nishiyama A.
- Journal Title
  
  PLoS One.
  
  Volume: 8(12) Issue: 12 Pages: e82082-e82082
- DOI
  10.1371/journal.pone.0082082
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590303, KAKENHI-PROJECT-24591204
[Journal Article] Angiotensin-converting enzyme inhibitor does not suppress renal angiotensin II levels in angiotensin I-infused rats.2013
- Author(s)
  Ohnishi K, Murase M, Nakano D, Pelisch N, Hitomi H, Kobori H, Morimoto S, Mori H, Masaki T, Ohmori K, Kohno M, Ichihara A, Nishiyama A.
- Journal Title
  
  J Pharmacol Sci.
  
  Volume: 122(2) Pages: 103-8
- NAID
  10031185402
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590303
[Journal Article] Aldosterone aggravates glucose intolerance induced by high fructose.2013
- Author(s)
  Sherajee SJ, Rafiq K, Nakano D, Mori H, Kobara H, Hitomi H, Fujisawa Y, Kobori H, Masaki T, Nishiyama A.
- Journal Title
  
  Eur J Pharmacol.
  
  Volume: 720(1-3) Issue: 1-3 Pages: 63-8
- DOI
  10.1016/j.ejphar.2013.10.051
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590303, KAKENHI-PROJECT-24591204
[Journal Article] Calcium channel blocker enhances beneficial effects of an angiotensin II AT1 receptor blocker against cerebrovascular-renal injury in type 2 diabetic mice.2013
- Author(s)
  Rafiq K, Sherajee SJ, Hitomi H, Nakano D, Kobori H, Ohmori K, Mori H, Kobara H, Masaki T, Kohno M, Nishiyama A.
- Journal Title
  
  PLoS ONE.
  
  Volume: 8(12)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12F02420
[Journal Article] Complement 3 activates the renal renin-angiotensin system by induction of epithelial-to-mesenchymal transition of the nephrotubulus in mice.2013
- Author(s)
  Zhou X, Fukuda N, Matsuda H, Endo M, Wang X, Saito K, Ueno T, Matsumoto T, Matsumoto K, Soma M, Kobayashi N, Nishiyama A.
- Journal Title
  
  American Journal of Physiology Renal Physiology
  
  Volume: 305(7)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591242
[Journal Article] Podocyte injury enhances filtration of liver-derived angiotensinogen and renal angiotensinIIgeneration.2013
- Author(s)
  T Matsusaka,F Niimura,I Pastan ,A Shintani, A Nishiyama , I Ichikawa.
- Journal Title
  
  Kidney Int.
  
  Volume: - Issue: 5 Pages: 1068-1077
- DOI
  10.1038/ki.2013.453
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249033, KAKENHI-PROJECT-23249047
[Journal Article] Aldosterone: a mediator of retinal ganglion cell death and the potential role in the pathogenesis in normal-tension glaucoma.2013
- Author(s)
  Nitta E, Hirooka K, Tenkumo K, Fujita T, Nishiyama A, Nakamura T, Itano T, Shiraga F.
- Journal Title
  
  Cell Death Dis.
  
  Volume: 4 Issue: 7 Pages: e711-e711
- DOI
  10.1038/cddis.2013.240
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590303
[Journal Article] Roles of Na⁺/H⁺ exchanger type 1 and intracellular pH in angiotensin II-induced reactive oxygen species generation and podocyte apoptosis.2013
- Author(s)
  Liu Y, Hitomi H, Diah S, Deguchi K, Mori H, Masaki T, Nakano D, Kobori H, Nishiyama A.
- Journal Title
  
  J Pharmacol Sci.
  
  Volume: 122(3) Pages: 176-83
- NAID
  10031185411
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590303
[Journal Article] Oxidative stress-induced glomerular mineralocorticoid receptor activation limits the benefit of salt reduction in Dahl salt-sensitive rats2012
- Author(s)
  Kitada K, Nakano D, Liu Y, Fujisawa Y, Hitomi H, Shibayama Y, Shibata H, Nagai Y, Mori H, Masaki T, Kobori H, Nishiyama A
- Journal Title
  
  PLoS ONE
  
  Volume: 7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590303
[Journal Article] Aldosterone induces insulin-like growth factor-1 receptor and hybrid receptor2012
- Author(s)
  Sherajee SJ, Fujita Y, Rafiq K, Nakano D, Mori H, Masaki T, Hara T, Kohno M, Nishiyama A, Hitomi H
- Journal Title
  
  Arterioscler Thromb Vasc Biol
  
  Volume: 32 Pages: 257-263
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590303
[Journal Article] Aldosterone induces p21-regulated apoptosis via increased synthesis and secretion of tumour necrosis factor-αin human proximal tubular cells2012
- Author(s)
  Kitada K, Nakano D, Hitomi H, Kobori H, Deguchi K, Mori H, Masaki T, Nishiyama A
- Journal Title
  
  Clin Exp Pharmacol Physiol
  
  Volume: 39 Pages: 858-863
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590303
[Journal Article] Liver angiotensinogen is the primary source of renal angiotensin II2012
- Author(s)
  Matsusaka T, Niimura F, Shimizu A, Pastan I, Saito A, Kobori H, Nishiyama A, Ichikawa I
- Journal Title
  
  J Am Soc Nephrol.
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591023
[Journal Article] Liver Angiotensinogen Is the Primary Source of Renal Angiotensin2012
- Author(s)
  松阪泰二、新村文男、西山成、市川家國, 他
- Journal Title
  
  J.Am.Soc.Nephrology
  
  Volume: (in print)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249033
[Journal Article] Oxidative stress-induced glomerular mineralocorticoid receptor activation olimits the benefit of salt reduction in Dahl salt-sensitive rats2012
- Author(s)
  K.Kitada, H.Shibata, et al.
- Journal Title
  
  PLoS One
  
  Volume: 7 Issue: 7 Pages: e41896-e41896
- DOI
  10.1371/journal.pone.0041896
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591018, KAKENHI-PROJECT-23590303, KAKENHI-PROJECT-24591204
[Journal Article] Aldosterone Does Not Contribute to Renal p21 Expression During the Development of Angiotensin II-Induced Hypertension in Mice2012
- Author(s)
  Nakano D, Minamino T, et al
- Journal Title
  
  Am J Hypertens
  
  Volume: 25 Issue: 3 Pages: 354-358
- DOI
  10.1038/ajh.2011.224
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390237, KAKENHI-PUBLICLY-23126504, KAKENHI-PROJECT-23590303, KAKENHI-PROJECT-23659411, KAKENHI-PROJECT-24390195
[Journal Article] Aldosterone does not contribute to renal p21 expression during the development of angiotensin II-induced hypertension in mice2012
- Author(s)
  Nakano D, Lei B, Kitada K, Hitomi H, Kobori H, Mori H, Deguchi K, Masaki T, Minamino T, Nishiyama A
- Journal Title
  
  Am J Hypertens
  
  Volume: 25 Pages: 354-358
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590303
[Journal Article] 結像型2次元フーリエ分光法による分光断層像計測技術2012
- Author(s)
  小林宏明、河尻武、矢野川果奈、西山成、田中直孝、高橋悟、石丸伊知郎
- Journal Title
  
  光学
  
  Volume: 41巻 1号 Pages: 36-44
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22360165
[Journal Article] Liver angiotensinogen is the primary source of renal angiotensin II.2012
- Author(s)
  Matsusaka T, Niimura F, Shimizu A, Pastan I, Saito A, Kobori H, Nishiyama A, Ichikawa I.
- Journal Title
  
  J Am Soc Nephrol.
  
  Volume: 23-7 Issue: 7 Pages: 1181-1189
- DOI
  10.1681/asn.2011121159
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249033, KAKENHI-PROJECT-23249047
[Journal Article] Aldosterone induces p21-regulated apoptosis via increased synthesis and secretion of tumour necrosis factor-α in human proximal tubular cells.2012
- Author(s)
  Kitada K, Nakano D, Hitomi H, Kobori H, Deguchi K, Mori H, Masaki T, Nishiyama A.
- Journal Title
  
  Clin Exp Pharmacol Physiol.
  
  Volume: 39(10) Issue: 10 Pages: 858-863
- DOI
  10.1111/j.1440-1681.2012.12001.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590303, KAKENHI-PROJECT-24591204
[Journal Article] Urinary angiotensinogen reflects the activity of intrarenal renin-angiotensin system in patients with IgA nephropathy.2011
- Author(s)
  Nishiyama A, et al.
- Journal Title
  
  Nephrol Dial Transplant.
  
  Volume: 26 Pages: 170-177
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590253
[Journal Article] アンジオテンシンII受容体拮抗薬2011
- Author(s)
  北田研人、中野大介、人見浩史、西山成
- Journal Title
  
  薬局 Vol.62
  
  Pages: 51-55
- Data Source
  KAKENHI-PROJECT-20590253
[Journal Article] Urinary angiotensinogen reflects the activity of intrarenal renin-angiotensin system in patients with IgA nephropathy2011
- Author(s)
  Nishiyama A、Konishi Y、Ohashi N
- Journal Title
  
  Nephrol Dial Transplant Vol.26
  
  Pages: 170-177
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590253
[Journal Article] 抗アルドステロン薬2011
- Author(s)
  北田研人、中野大介、西山成
- Journal Title
  
  Angiology Frontier Vol.10
  
  Pages: 31-38
- Data Source
  KAKENHI-PROJECT-20590253
[Journal Article] Pathophysiological roles of Aldosterone and mineralocorticoid receptor in the kidney2011
- Author(s)
  Rafiq K、Hitomi H、Nakano D、Nishiyama A
- Journal Title
  
  J.Pharmacol. Sci Vol.115
  
  Pages: 1-7
- NAID
  10029891280
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590253
[Journal Article] 腎とレニン・アンジオテンシン・アルドステロン系/高血圧2010
- Author(s)
  西山成, 他
- Journal Title
  
  Pharma Medica.
  
  Volume: 28 Pages: 29-33
- Data Source
  KAKENHI-PROJECT-20590253
[Journal Article] Mineralocorticoid receptor blockade enhances the anti-proteinuric effect of an angiotensin II blocker through inhibiting podocyte injury in type 2 diabetic rats.2010
- Author(s)
  Nishiyama A, et al.
- Journal Title
  
  J.Pharmacol.Exp.Ther.
  
  Volume: 332 Pages: 1072-1080
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590253
[Journal Article] New approaches to blockade of the renin-angiotensin-aldosterone system : Overview of the regulation of the renin-angiotensin-aldosterone system.2010
- Author(s)
  Nishiyama A, et al.
- Journal Title
  
  J.Pharmacol.Sci.
  
  Volume: 113 Pages: 289-291
- NAID
  10027745720
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590253
[Journal Article] 腎とレニン・アンジオテンシン・アルドステロン系/高血圧2010
- Author(s)
  西山成、中野大介、人見浩史
- Journal Title
  
  Pharma Medica Vol.28
  
  Pages: 29-33
- Data Source
  KAKENHI-PROJECT-20590253
[Journal Article] 腎RAAS(アルドステロンを中心に)と酸化ストレス2010
- Author(s)
  北田研人、中野大介、西山成
- Journal Title
  
  最新医学 Vol.65
  
  Pages: 63-70
- Data Source
  KAKENHI-PROJECT-20590253
[Journal Article] アルドステロンブレイクスルー2010
- Author(s)
  北田研人、中野大介、西山成
- Journal Title
  
  腎と透析 Vol.68
  
  Pages: 977-982
- Data Source
  KAKENHI-PROJECT-20590253
[Journal Article] RASSとたんぱく尿2010
- Author(s)
  西山成、中野大介、人見浩史
- Journal Title
  
  腎臓 Vol.32
  
  Pages: 190-195
- Data Source
  KAKENHI-PROJECT-20590253
[Journal Article] 慢性腎疾患患者における腎臓局所レニン・アンジオテンシン系の評価2010
- Author(s)
  西山成, 他
- Journal Title
  
  臨床薬理の進歩
  
  Volume: 31 Pages: 33-39
- Data Source
  KAKENHI-PROJECT-20590253
[Journal Article] 腎とRASSオーバービュー～腎障害、高血圧への関与～2010
- Author(s)
  山本龍夫、西山成
- Journal Title
  
  日本腎学会誌 Vol.52
  
  Pages: 87-91
- Data Source
  KAKENHI-PROJECT-20590253
[Journal Article] Mineralocorticoid receptor blockad enhances the anti-proteinuric effect of an angiotensin II blocker through inhibiting podocyte injury in type 2 diabetic rats2010
- Author(s)
  Nishiyama A、Kobori H、Konishi Y
- Journal Title
  
  J.Pharmacol. Exp. Ther Vol.332
  
  Pages: 1072-1080
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590253
[Journal Article] Role of (pro)renin receptor in cardiovascular cells from the aspect ofsignaling2010
- Author(s)
  Hitomi H、Liu G、Nishiyama A
- Journal Title
  
  Front Biosci 1
  
  Pages: 1246-1249
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590253
[Journal Article] New approaches to blockade of the Renin-Angiotensin-Aldosterone system : Mineralocorticoid receptor blockers exert antihypertensive and renoprotective effects independently of the renin-angiotensin system.2010
- Author(s)
  Nishiyama A, et al.
- Journal Title
  
  J.Pharmacol.Sci.
  
  Volume: 113 Pages: 310-314
- NAID
  10027745871
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590253
[Journal Article] New approaches to blockade of the reninangiotensin-aldosterone system : Overview of the regulation of the renin-angiotensin-aldosterone system2010
- Author(s)
  Nishiyama A、Mistuyama-Kim S
- Journal Title
  
  J.Pharmacol. Sci Vol.113
  
  Pages: 289-291
- NAID
  10027745720
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590253
[Journal Article] 慢性腎疾患患者における腎臓局所レニン・アンジオテンシン系の評価2010
- Author(s)
  西山成、人見浩史、今西政仁、小堀浩幸
- Journal Title
  
  臨床薬理の進歩 Vol.31
  
  Pages: 33-39
- Data Source
  KAKENHI-PROJECT-20590253
[Journal Article] New approaches to blockade of the Renin-Angiotensin-Aldosterone system : MR blockers exert antihypertensive and renoprotective effects independently of the renin-angiotensin system2010
- Author(s)
  Nishiyama A、Hasegawa K、Diah S、Hitomi H
- Journal Title
  
  J.Pharmacol. Sci Vol.113
  
  Pages: 310-314
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590253
[Journal Article] アルドステロンブロッカーの腎保護作用研究の最先端2010
- Author(s)
  中野大介、人見浩史、西山成
- Journal Title
  
  血圧 Vol.17
  
  Pages: 512-514
- Data Source
  KAKENHI-PROJECT-20590253
[Journal Article] RASSとたんぱく尿2010
- Author(s)
  西山成, 他
- Journal Title
  
  腎臓
  
  Volume: 32 Pages: 190-195
- Data Source
  KAKENHI-PROJECT-20590253
[Journal Article] The opposite roles of nNOS in cardiac ischemia-reperfusion-induced injury and in ischemia preconditioning-induced cardioprotection in mice.2009
- Author(s)
  Lu XM, Zhang GX, Yu YQ, Kimura S, Nishiyama A, Matsuyoshi H, Shimizu J, Takaki M.
- Journal Title
  
  J Physiol Sci.
- NAID
  10025218967
- Data Source
  KAKENHI-PROJECT-19590250
[Journal Article]2009
- Author(s)
  西山成
- Journal Title
  
  高血圧(第4版)上-日本における最新の研究動向血管作動性物質-生合成、分泌、生理作用-アルドステロン(日本臨床社)
  
  Pages: 188-193
- Data Source
  KAKENHI-PROJECT-20590253
[Journal Article] Tissue Doppler echocardiography for predicting arterial stiffnes aessed by cardio-anke vascular ndex2009
- Author(s)
  Masugata H, Senda S, Goda F, YamA, Okuyama H, Kohno T, Hosomi N, Yukiiri K, Noma T, Kiyomoto H, Murao K, Nishiyama A, Kohno M
- Journal Title
  
  Tohoku J Exp Med 217
  
  Pages: 139-146
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590945
[Journal Article] Insulin attenuates apoptosis induced by high glucose via the PI3-kinase/Akt pathway in rat peritoneal mesothelial cells2009
- Author(s)
  Kaifu K, Kiyomoto H, Hitomi H, Matsubara K, Hara T, Moriwaki K, Ihara G, Fujita Y, Sugasawa S, Nagata D, Nishiyama A, Kohno M.
- Journal Title
  
  Nephrol Dial Transplant 24(3)
  
  Pages: 809-815
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590830
[Journal Article] The expression of matrix metalloproteinase-13 (MMP3) is ineased in vessels with blood-brain barrier impairment in a stroke-prone hypertensive model2009
- Author(s)
  Ueno M, Wu B, Nishiyama A, Huang C, Hosomi N, Kusaka T, Nakagawa T, Onodera M, Kido M, Sakamoto H
- Journal Title
  
  Hypertens Res
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590945
[Journal Article] Do vasculature reactive oxygen species play a role in the mobilization of bone marrow endothelial progenitor cells?2008
- Author(s)
  Kiyomoto H, Nishiyama A.
- Journal Title
  
  J. Hypertens. 26
  
  Pages: 188-190
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590253
[Journal Article] Strict angiotensin blockade prevents the augmentation of intrarenal angioensin II and podocyte abnormalitiesn ty 2 diatic rats with microalbuminuria2008
- Author(s)
  Nishiyama A, Nakagawa T, Koori Nagai Y, Okada N, Konishi Y, Morikawa T, Okumura M, Meda I, Kiyomoto H, Hosomi N, Mori T, Ito S, Imanishi M
- Journal Title
  
  J Hypertens 26
  
  Pages: 1849-1859
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590945
[Journal Article] ミネラロコルチコイド受容体拮抗薬.2008
- Author(s)
  西山成, 他
- Journal Title
  
  日本薬理学学会誌. 132
  
  Pages: 244-246
- NAID
  10024384088
- Data Source
  KAKENHI-PROJECT-20590253
[Journal Article] Aldosterone induces myofibroblastic transdifferentiation and collagen gene expression through the Rho-kinase dependent signaling pathway in rat mesangial cells2008
- Author(s)
  Diah S, Zhang GX, Nagai Y, Zhang W, Gang L, Kimura S, Hamid MRWA, Tamiya T, Nishiyama A, Hitomi H.
- Journal Title
  
  Exp Cell Res 314
  
  Pages: 3654-3662
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590250
[Journal Article] ARBとCCBによる尿細管間質障害治療2008
- Author(s)
  西山成、清元秀泰
- Journal Title
  
  医学のあゆみ 225(4)
  
  Pages: 321-325
- Data Source
  KAKENHI-PROJECT-17590830
[Journal Article] strict angiotensin blockade prevents the augmentation of intrarenal angio tensin ll and podocyte abnormalities in type 2 diabetic rats with microalbuminuria.2008
- Author(s)
  Nishiyama A, et al.
- Journal Title
  
  J. Hypertens. 26
  
  Pages: 1849-1859
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590253
[Journal Article] 腎内レニン・アンジオテンシン活性.2008
- Author(s)
  西山成
- Journal Title
  
  腎と透析. 64 : 64
  
  Pages: 11-15
- Data Source
  KAKENHI-PROJECT-20590253
[Journal Article] ARBとCCBによる尿細管間質障害治療.2008
- Author(s)
  西山成, 他
- Journal Title
  
  医学のあゆみ 225
  
  Pages: 321-325
- Data Source
  KAKENHI-PROJECT-20590253
[Journal Article] Possible involvement of Rho-kinase in aldosterone-iducevascular smth muscle cell remodeling2008
- Author(s)
  Miyata K, Hitomi H, Guo P, Zhang GX, Kimura S, Kiyomoto H, Hosomi N, Kagami S, Kohno M, Nishiyama A
- Journal Title
  
  Hypertens Res 31
  
  Pages: 1407-1413
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590945
[Journal Article] Strict angiotensin blockade prevents the augmentation of intrarenal angiotens in II and podocyte abnormalities in type 2 diabetic rats with microalbuminuria.2008
- Author(s)
  Nishiyama A
- Journal Title
  
  J Hypertens. 26
  
  Pages: 1849-1859
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590945
[Journal Article] Do vasculature reactive oxygen species play a role in the mobilization of bone marrow endothelial progenitor cells?2008
- Author(s)
  Kiyomoto H, Nishiyama A
- Journal Title
  
  J Hypertens 26
  
  Pages: 188-190
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590830
[Journal Article] Possible involvement of Rho-kinase in aldosterone-induced vascular remodeling2008
- Author(s)
  Miyata K, Sun GP, Guo P, Hitomi H, Kimura S, Kiyomoto H, Hosomi N, Kohno M and Nishiyama A.
- Journal Title
  
  Hypertens Res 31
  
  Pages: 1407-1413
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590250
[Journal Article] Role of mitochondria in angiotensn II-induced reactive oxygen species and mitogen-activated protein kinase activation2007
- Author(s)
  Zhang GX, Lu XM, Kimura S, Nishiyama A.
- Journal Title
  
  Cardiovasc Res 76
  
  Pages: 204-212
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590250
[Journal Article] Angiotensin II and oxidative stress2007
- Author(s)
  Hitomi H, Kiyomoto H, Nishiyama A
- Journal Title
  
  Curr Opin Cardiol 22(4)
  
  Pages: 311-315
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590830
[Journal Article] Role of AT1 receptor in isoproterenol-induced cardiac hypertrophy and oxidative stress in mice.2007
- Author(s)
  Zhang G, Ohmori K, Nagai Y, Fujisawa Y, Nishiyama A, Abe Y, Kimura S.
- Journal Title
  
  J Mol Cell Cardiol. (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590220
[Journal Article] Aldosterone suppresses insulin signaling via the downregulation of insulin receptor substrate-1 in vascular smooth muscle cells.2007
- Author(s)
  Hitomi H, Kiyomoto H, Nishiyama A, et. al.
- Journal Title
  
  Hypertension 50(4)
  
  Pages: 750-755
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590830
[Journal Article] Effects of adrenomedullin 2 on regional hemodynamics in conscious rats.2007
- Author(s)
  Fujisawa Y, Nagai Y, Miyatake A, Miura K, Nishiyama A, Kimura S, Abe Y.
- Journal Title
  
  Eur J Pharmacol. 558
  
  Pages: 128-132
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590220
[Journal Article] Effects of adrenomedullin 2 on regional hemodynamics in conscious rats2007
- Author(s)
  Fujisawa Y, Nagai Y, Miyatake A, Miura K, Nishiyama A, Kimura S, Abe Y.
- Journal Title
  
  Eur J Pharmacol 558
  
  Pages: 128-132
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590250
[Journal Article] Role of AT1 receptor in isoproterenol-induced cardiac hypertrophy and oxidative stress in mi2007
- Author(s)
  Zhang GX, Ohmori K, Nagai Y, Fujisawa Y, Nishiyama A, Abe Y, Kimura S
- Journal Title
  
  J Mol Cell Cardiol 42
  
  Pages: 804-811
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590250
[Journal Article] Involvement of endogenous nitric oxide in angiotensin II-induced activation of vascular mitogen-activated protein kinases2007
- Author(s)
  Zhang GX, Nagai Y, Nakagawa T, Miyanaka H, Fujisawa Y, Nishiyama A, Izuishi K, Ohmori K, Kimura S.
- Journal Title
  
  Am J Physiol Heart Circ Physiol 293
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590250
[Journal Article] Angiotensin II and oxidative stress.2007
- Author(s)
  Hitomi H, Kiyomoto H, Nishiyama A.
- Journal Title
  
  Curr Opin Cardiol 22(4)
  
  Pages: 311-315
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590830
[Journal Article] Na・水調節におけるレニン・アンジオテンシン・アルドステロン系の役割.2006
- Author(s)
  西山成, 安部陽一
- Journal Title
  
  ホルモンと臨床. 54
  
  Pages: 403-410
- NAID
  10017442522
- Data Source
  KAKENHI-PROJECT-17790171
[Journal Article] Renal interstitial fluid ATP responses to arterial pressure and tubuloglomerular feedback activation during treatment with a calcium channel blocker.2006
- Author(s)
  Nishiyama A, et al.
- Journal Title
  
  Am.J.Physiol.Heart Circ.Physiol. 290
- Data Source
  KAKENHI-PROJECT-17790171
[Journal Article] Contribution of reactive oxygen species to the pathogenesis of left ventricular failure in Dahl salt-sensitive hypertensive rats : effects of angiotensin II blockade.2006
- Author(s)
  Guo P, Nishiyama A, Rahman M, Nagai Y, Noma T, Namba T, Ishizawa M, Murakami K, Miyatake A, Kimura S, Mizushige K, Abe Y, Ohmori K, Kohno M.
- Journal Title
  
  J Hypertens. 24
  
  Pages: 1097-1104
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590220
[Journal Article] Interferon-gamma enhances superoxide production in human mesangial cells via the JAK-STAT pathway.2006
- Author(s)
  Moriwaki K, Kiyomoto H, Hitomi H, Hara T, Ohmori K, Nishiyama A, et al.
- Journal Title
  
  Kidney Int. 70(4)
  
  Pages: 788-793
- Data Source
  KAKENHI-PROJECT-17590830
[Journal Article] Augmentationof intrareal angiotensin els in uninephrectomd osterone/slt -treated hypertensive rats ; renoprotece effects of an ahigh dose of olmesartan2006
- Author(s)
  Fan YY, Baba R, Nagai Y, Miyatake Hosomi N, Kimura S, Sun GP, Kohno M, Fujita M, Abe Y, Nishiyama A.
- Journal Title
  
  Hypertens Res 29
  
  Pages: 169-178
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590945
[Journal Article] 輸入細動脈,輸出細動脈の分子構造と機能.2006
- Author(s)
  西山成, 安部陽一
- Journal Title
  
  日本臨床. 64
  
  Pages: 107-112
- Data Source
  KAKENHI-PROJECT-17790171
[Journal Article] Effects of adrenomedullin on cardiac oxidative stress and collagen accumulation in aldosterone-dependent malignant hypertensive rats.2006
- Author(s)
  Rahman M, Nishiyama A, Guo P, Nagai Y, Zhang GX, Fujisawa Y, Fan YY, Kimura S, Hosomi N, Omori K, Abe Y, Kohno M.
- Journal Title
  
  J Pharmacol Exp Ther. 318
  
  Pages: 1323-1329
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590220
[Journal Article] Synergistic effect of mechanical stretch and angiotensin II on superoxide production via NADPH oxidase in vascular smooth muscle cells.2006
- Author(s)
  Hitomi H, Fukui T, Moriwaki K, Matsubara K, Sun GP, Rahman M, Nishiyama A, Kiyomoto H, Kimura S, Ohmori K, Abe Y, Kohno M.
- Journal Title
  
  J Hypertens. 24
  
  Pages: 1089-1095
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590220
[Journal Article] Reno-protective effects of aldosterone blockade.2006
- Author(s)
  Nishiyama A, Abe Y.
- Journal Title
  
  J.Pharmacol.Sci. 100
  
  Pages: 9-16
- Data Source
  KAKENHI-PROJECT-17790171
[Journal Article] アルドステロンと酸化ストレス2006
- Author(s)
  河野雅和, 西山成
- Journal Title
  
  治療学. 40
  
  Pages: 29-33
- Data Source
  KAKENHI-PROJECT-17790171
[Journal Article] Roles of adrenomedullin2 in regulating the cardiovascular and sympathetic nervous systems in conscious rats.2006
- Author(s)
  Fujisawa Y, Nagai Y, Miyatake A, Miura K, Shokoji T, Nishiyama A, Kimura S, Abe Y.
- Journal Title
  
  Am J Physiol Heart Circ Physiol. 290
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590220
[Journal Article] Interferon-γ enhances superoxide production in human mesangial cells via the JAK-STAT pathway2006
- Author(s)
  Moriwaki K, Kiyomoto H, Hitomi H, Ihara G, Kaifu K, Matsubara K, Hara T, Kondo N, Ohmori K, Nishiyama A, Fukui T, Kohno M
- Journal Title
  
  Kidney Int 70(4)
  
  Pages: 788-93
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590830
[Journal Article] Synergistic effect of mechanical stretch and angiotensin II on superoxide production via NADPH oxidase in vascular smooth muscle cells2006
- Author(s)
  Hitomi H, Fukui T, Moriwaki K, Matsubara K, Sun GP, Rahman M, Nishiyama A, Kiyomoto H, Kimura S, Ohmori K, Abe Y, Kohno M
- Journal Title
  
  J Hypertens 24
  
  Pages: 1089-95
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590830
[Journal Article] Effects of adrenomedullin on cardiac oxidative stress and collagen accumulatio in aldoseroneependent malignant hypertensive rats2006
- Author(s)
  Rahman M, Nishiyama A, Guo P, Nagai Y, Zhang GX, Fujisawa Y, Fan YY, Kimura S, Hosomi N, Omori K, Abe Y, Kohno M
- Journal Title
  
  J Pharmacol Exp Ther 318
  
  Pages: 1323-1329
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590945
[Journal Article] 腎障害進展におけるアルドステロン/ミネラロコルチコイド受容体と酸化ストレスの役割2006
- Author(s)
  西山成、今西政仁、清元秀泰、河野雅和、安部陽一
- Journal Title
  
  臨床薬理の進歩 27
  
  Pages: 139-144
- Data Source
  KAKENHI-PROJECT-17590830
[Journal Article] 腎内RAA系と酸化ストレスの制御機構と病態への関与.2006
- Author(s)
  西山成, 安部陽一.
- Journal Title
  
  腎と透折 60
  
  Pages: 307-312
- Data Source
  KAKENHI-PROJECT-17790171
[Journal Article] Reno-protective effects of aldosterone blockade.2006
- Author(s)
  Nishiyama A, Abe Y.
- Journal Title
  
  J. Pharmacol. Sci. 100
  
  Pages: 9-16
- Data Source
  KAKENHI-PROJECT-17790171
[Journal Article] 輸入細動脈,輸出細動脈の分子構造と機能.2006
- Author(s)
  西山成, 安部陽一.
- Journal Title
  
  日本臨床 64
  
  Pages: 107-112
- Data Source
  KAKENHI-PROJECT-17790171
[Journal Article] Effects of calcium channel blockade on angiotensin II-induced peritubular ischemia in rats.2006
- Author(s)
  Kondo N, Kiyomoto H, Hitomi H, Moriwaki K, Hra T, Abe Y, Kohno M, Nishiyama A, et al.
- Journal Title
  
  J Pharmacol Exp Ther. 316(3)
  
  Pages: 1047-1052
- Data Source
  KAKENHI-PROJECT-17590830
[Journal Article] Involvements of Rho-kinase and TGF-beta pathways in aldosterone-induced renal injury.2006
- Author(s)
  Sun GP, Kohno M, Guo P, Nagai Y, Miyata K, Fan YY, Kimura S, Kiyomoto H, Ohmori K, Li DT, Abe Y, Nishiyama A.
- Journal Title
  
  J Am Soc Nephrol. 17
  
  Pages: 2193-2201
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590220
[Journal Article] 腎内RAA系と酸化ストレスの制御機構と病態への関与.2006
- Author(s)
  西山成, 安部陽一
- Journal Title
  
  腎と透析. 60
  
  Pages: 307-312
- Data Source
  KAKENHI-PROJECT-17790171
[Journal Article] Renal interstitial fluid ATP responses to arterial pressure and tubuloglomerular feedback activation during treatment with a calcium channel blocker.2006
- Author(s)
  Nishiyama A, et al.
- Journal Title
  
  Am. J. Physiol. Heart Circ. Physiol. 290
- Data Source
  KAKENHI-PROJECT-17790171
[Journal Article] アルドステロン依存性腎障害における酸化ストレス、MAPキナーゼ、Rhoキナーゼの役割2006
- Author(s)
  人見浩史、清元秀泰、河野雅和、西山成
- Journal Title
  
  内分泌・糖尿病科 23(6)
  
  Pages: 575-580
- Data Source
  KAKENHI-PROJECT-17590830
[Journal Article] アルドステロン関連研究のジレンマについて2006
- Author(s)
  西山成
- Journal Title
  
  治療学. 40
  
  Pages: 22-23
- Data Source
  KAKENHI-PROJECT-17790171
[Journal Article] 腎障害におけるアルドステロン/MRと酸化ストレスの役割.2006
- Author(s)
  西山成, 他
- Journal Title
  
  臨床薬理の進歩. 27
  
  Pages: 139-144
- Data Source
  KAKENHI-PROJECT-17790171
[Journal Article] Augmentation of intrarenal angiotensin II levels in uninephrectomized aldosterone/salt-treated hypertensive rats; renoprotective effects of an ultrahigh dose of olmesartan.2006
- Author(s)
  Fan YY, Baba R, Nagai Y, Miyatake A, Hosomi N, Kimura S, Sun GP, Kohno M, Fujita M, Abe Y, Nishiyama A.
- Journal Title
  
  Hypertens Res. 29
  
  Pages: 169-78
- NAID
  10018347547
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590220
[Journal Article] 腎不全および維持血液透析における酸化ストレスの評価とその対策に関する研究2005
- Author(s)
  東山智香子、清元秀泰、西山成、今西政仁、河野雅和
- Journal Title
  
  腎臓 27(2)
  
  Pages: 105-109
- Data Source
  KAKENHI-PROJECT-17590830
[Journal Article] D-allose, an all-cis aldo-hexose, suppresses development of salt induced hypertension in Dahl rats.2005
- Author(s)
  Kimura S, Zhang GX, Nishiyama A, Nagai Y, Nakagawa T, Miyanaka H, Fujisawa Y, Miyatake A, Nagai T, Tokuda M, Abe Y.
- Journal Title
  
  J Hypertens. 23
  
  Pages: 1887-1894
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590220
[Journal Article] Role of NAD(P)H oxidase-and mitochondria-derived reactive oxygen species in cardioprotection of ischemic reperfusion injury by angiotensin II.2005
- Author(s)
  Kimura S, Zhang GX, Nishiyama A, Shokoji T, Yao L, Fan YY, Rahman M, Suzuki T, Maeta H, Abe Y.
- Journal Title
  
  Hypertension. 45
  
  Pages: 860-866
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590220
[Journal Article] Involvement of aldosterone and mineralocorticoid receptor in rat mesangial cell proliferation and deformability.2005
- Author(s)
  Akira Nishiyama
- Journal Title
  
  Hypertension. (In press)
- Data Source
  KAKENHI-PROJECT-15790136
[Journal Article] Aldosterone Stimulates Reactive Oxygen Species Production through Activation of NADPH Oxidase in Rat Mesangial Cells2005
- Author(s)
  Miyata K, Rahman M, Shokoji T, Nagai Y, Zhang GX, Sun GP, Kimura S, Yukimura T, Kiyomoto H, Kohno M, Abe Y, Nishiyama A
- Journal Title
  
  J Am Soc Nephrol 16(10)
  
  Pages: 2906-2912
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590830
[Journal Article] Aldosterone stimulates collagen gene expression and synthesis via activation of ERK1/2 in renal fibroblasts.2005
- Author(s)
  Nagai Y, Miyata K, Sun GP, Rahman M, Kimura S, Miyatake A, Kiyomoto H, Kohno M, Abe Y, Yoshizumi M, Nishiyama A.
- Journal Title
  
  Hypertension. 46
  
  Pages: 1039-1045
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590220
[Journal Article] Involvement of aldosterone and mineralocorticoid receptor in rat mesangial cell proliferation and deformability.2005
- Author(s)
  Nishiyama A, et al.
- Journal Title
  
  Hypertension. 45
  
  Pages: 710-716
- Data Source
  KAKENHI-PROJECT-17790171
[Journal Article] Involvement of aldosterone and mineralocorticoid receptors in rat mesangial cell proliferat ion and deformability.2005
- Author(s)
  Nishiyama Akira
- Journal Title
  
  Hypertension 45
  
  Pages: 710-716
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390158
[Journal Article] Involvement of aldosterone and mineralocorticoid receptors in rat mesangial cell proliferation and deformability.2005
- Author(s)
  Nishiyama Akara
- Journal Title
  
  Hypertension 45
  
  Pages: 710-716
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390158
[Journal Article] アルドステロンの新しい腎作用.2005
- Author(s)
  西山成, 安部陽一.
- Journal Title
  
  Hypertension Frontier 8
  
  Pages: 47-59
- Data Source
  KAKENHI-PROJECT-17790171
[Journal Article] Involvement of aldosterone and mineralocorticoid receptors in rat mesangial cell proliferation and deformability.2005
- Author(s)
  Nishiyama Akira
- Journal Title
  
  Hypertension 45
  
  Pages: 710-716
- Data Source
  KAKENHI-PROJECT-16390158
[Journal Article] Reduction of oxidized low-density lipoprotein by the long-term use of vitamin E-coated dialyzers in hemodialysis patients2005
- Author(s)
  Hara T, Takahashi N, Kiyomoto H, Moriwaki K, Fujioka H, Matsubara K, Kondo N, Shokoji T, Kiyomoto K, Hirohata M, Ishizu T, Akiyama K, Nishiyama A, Ohmori K, Kohno M
- Journal Title
  
  Dialysis & Transplantation 33(4)
  
  Pages: 197-202
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590830
[Journal Article] Involvement of aldosterone and mineralocorticoid receptors in rat mesangial cell proliferation and deformability.2005
- Author(s)
  Nishiyama Akira
- Journal Title
  
  Hypertension 45
  
  Pages: 710-716
- Data Source
  KAKENHI-PROJECT-17590220
[Journal Article] The SOD mimetic tempol ameliorates glomerular injury and reduces mitogen-activated protein kinase activity in Dahl salt-sensitive rats.2004
- Author(s)
  Nishiyama A.et al.
- Journal Title
  
  J.Am.Soc.Nephrol. 15
  
  Pages: 306-315
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590230
[Journal Article] Role of interstitial ATP and adenosine in the regulation of renal hemodynamics and microvascular function.2004
- Author(s)
  Nishiyama Akira
- Journal Title
  
  Hypertens. Res. 27
  
  Pages: 791-804
- NAID
  10014387419
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390158
[Journal Article] The SOD mimetic tempol ameliorates glomerular injury and reduces mitogen-activated protein kinase actibvity in Dahl salt-sensitive rats.2004
- Author(s)
  Nishiyama A. et al.
- Journal Title
  
  J.Am.Soc.Nephrol. 15
  
  Pages: 306-315
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590230
[Journal Article] Role of interstitial ATP and adenosine in the regulation of renal hemodynamics and microvascular function.2004
- Author(s)
  Nihsiyama Akira
- Journal Title
  
  Hypertens. Res. 27
  
  Pages: 791-804
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390158
[Journal Article] The SOD mimetic tempol ameliorates glomerular injury and reduces mitogen-activated protein kinase activity in Dahl salt-sensitive rats.2004
- Author(s)
  Nishiyama Akira
- Journal Title
  
  J.Am.Soc.Nephrol. 15
  
  Pages: 306-315
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390158
[Journal Article] Effects of AT1 receptor blockade on renal injury and mitogen-activated protein kinase activity in Dahl salt-sensitive rats.2004
- Author(s)
  Nishiyama Akira
- Journal Title
  
  Kidney Int. 65
  
  Pages: 972-981
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390158
[Journal Article] Effects of AT1 receptor blockade on renal injury and mitogen-activated protein activity in Dahl salt-sensitive rats.2004
- Author(s)
  Nishiyama Akira
- Journal Title
  
  Kidney Int. 65
  
  Pages: 972-981
- Data Source
  KAKENHI-PROJECT-16390158
[Journal Article] Possible contributions of reactive oxygen species and mitogen-activated protein kinase to renal injury in aldosterone/salt-induced hypertensive rats.2004
- Author(s)
  Nishiyama Akira
- Journal Title
  
  Hypertension 43
  
  Pages: 841-848
- Data Source
  KAKENHI-PROJECT-16390158
[Journal Article] Possible contribution of reactive oxygen species and mitogen-activated protein kinase to renal injury in aldosterone/salt-induced hypertensive rats.2004
- Author(s)
  Nishiyama A.et al.
- Journal Title
  
  Hypertension 43
  
  Pages: 841-848
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590230
[Journal Article] Possible contribution of reactive oxygen species and mitogen-activated protein kinase to renal injury in aldosterone/salt-induced hypertensive rats.2004
- Author(s)
  Nishiyama A. et al.
- Journal Title
  
  Hypertension 43・4
  
  Pages: 841-848
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590230
[Journal Article] The SOD mimetic tempol ameliorates glomerular injury and reduces mitogen-activated protein kinase activity in Dahl salt-sensitive rats.2004
- Author(s)
  Nishiyama Akira
- Journal Title
  
  J. Am. Soc. Nephrol. 15
  
  Pages: 306-315
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390158
[Journal Article] The SOD mimetic tempol ameliorates glomerular injury and reduces MAPK activity in Dahl salt-sensitive rats.2004
- Author(s)
  Akira Nishiyama
- Journal Title
  
  J.Am.Soc.Nephrol. 15
  
  Pages: 306-315
- Data Source
  KAKENHI-PROJECT-15790136
[Journal Article] Possible contributions of reactive oxygen species and mitogen-activated protein kinase to renal injury in aldosterone/salt-induced hypertensive rats.2004
- Author(s)
  Akira Nishiyama
- Journal Title
  
  Hypertension. 43
  
  Pages: 841-848
- Data Source
  KAKENHI-PROJECT-15790136
[Journal Article] Effects of AT1 receptor blockade on renal injury and mitogen-activated protein kinase activity in Dah1 salt-sensitive rats.2004
- Author(s)
  Nishiyama Akira
- Journal Title
  
  Kidney Int. 65
  
  Pages: 972-981
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390158
[Journal Article] Role of interstitial ATP and adenosine in the regulation of renal hemodynamics and microvascular function.2004
- Author(s)
  Akira Nishiyama
- Journal Title
  
  Hypertens.Res. 27
  
  Pages: 791-804
- NAID
  10014387419
- Data Source
  KAKENHI-PROJECT-15790136
[Journal Article] Effects of ATI receptor blockade on renal injury and mitogen-activated protein kinase activity in Dahl salt-sensitive rats.2004
- Author(s)
  Nishiyama A.et al.
- Journal Title
  
  Kidney Int. 65
  
  Pages: 972-981
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590230
[Journal Article] Effects of AT_1 receptor blockade on renal injury and mitogen-activated protein activity in Dahl salt-sensitive rats.2004
- Author(s)
  Akira Nishiyama
- Journal Title
  
  Kidney Int. 65
  
  Pages: 972-981
- Data Source
  KAKENHI-PROJECT-15790136
[Journal Article] Effects of AT1 receptor blockade on renal injury and mitogen-activated protein activity in Dahl salt-sensitive rats.2004
- Author(s)
  Nishiyama A. et al.
- Journal Title
  
  Kidney Int. 65・3
  
  Pages: 972-981
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590230
[Journal Article] Role of angiotensin II and reactive oxygen species in cyclosporine A-dependent hypertension.2003
- Author(s)
  Nishiyama A.et al.
- Journal Title
  
  Hypertension 42
  
  Pages: 754-760
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590230
[Journal Article] Role of angiotensin II and reactive oxygen species in cyclosporine A-dependent hypertension.2003
- Author(s)
  Nishiyama A.
- Journal Title
  
  Hypertension 42・4
  
  Pages: 754-760
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590230
[Patent] 細胞増殖遅延剤、それを含む化粧品、及び細胞増殖を遅延させる方法2023
- Inventor(s)
  西山　成、他
- Industrial Property Rights Holder
  西山　成、他
- Industrial Property Rights Type
  特許
- Filing Date
  2023
- Overseas
- Data Source
  KAKENHI-PROJECT-22K19712
[Patent] 細胞増殖遅延剤、それを含む化粧品、及び細胞増殖を遅延させる方法2022
- Inventor(s)
  西山成
- Industrial Property Rights Holder
  西山成
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2022-004569
- Filing Date
  2022
- Data Source
  KAKENHI-PROJECT-22K19712
[Patent] プロレニン受容体に対する抗体またはその抗原結合断片、およびその用途2016
- Inventor(s)
  西山　成, 他
- Industrial Property Rights Holder
  西山　成, 他
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2016-215385
- Filing Date
  2016-11-02
- Acquisition Date
  2016-12-02
- Data Source
  KAKENHI-PROJECT-26460343
[Presentation] Klotho deficiency induces regulatory T cells in murine lupus nephritis.2023
- Author(s)
  Tsuneo Takenaka, Naohito Ishii, Yoshifumi Kurosaki, Takashi Miyazaki, Akira Nishiyama, Matsuhiko Hayashi
- Organizer
  欧州腎臓学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K07702
[Presentation] Pathophysiology of Hypertension -From a new perspectives2023
- Author(s)
  西山　成
- Organizer
  第45会日本高血圧学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-23K24771
[Presentation] 神経膠芽腫に対する希少糖D-alloseの効果とエネルギー代謝との関連2023
- Author(s)
  西山成、菅田峻光、北田研人、ラフマンアサダ、三宅啓介.
- Organizer
  第143回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-22K19712
[Presentation] 高食塩接種が各骨のナトリウム・カリウム含量に与える影響2023
- Author(s)
  北田　研人，宗定　優紘，中野　大介，西山　成
- Organizer
  第52回日本心脈管作動物質学会
- Data Source
  KAKENHI-PROJECT-20K20664
[Presentation] カラダの水分保持技術創出を目指したバイオミメティクス～肺魚の夏眠から学ぶ～2023
- Author(s)
  北田研人、西山　成
- Organizer
  黒潮カンファレンス
- Data Source
  KAKENHI-PROJECT-23K24771
[Presentation] Klotho deficiency induces regulatory T cells in murine lupus nephritis2023
- Author(s)
  Tsuneo Takenaka, Naohito Ishii, Yoshifumi Kurosaki, Tsutomu Inoue, Takashi Miyazaki, Akira Nishiyama, Matsuhiko Hayashi
- Organizer
  欧州腎臓学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08641
[Presentation] Raman imaging grasped the molecular changes during the cell differentiation of human induced pluripotent stem cells into erythropoietin-producing cells2022
- Author(s)
  Ishigaki, M., Hitomi, H., Ozaki, Y., Nishiyama, A.
- Organizer
  SCIX 2022
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K05556
[Presentation] Onco-Hypertension.2022
- Author(s)
  Nishiyama A.
- Organizer
  International SHR meeting 2022.
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19712
[Presentation] 肝細胞がんラットは，組織ナトリウム・体液貯留を伴う体質量の減少を示す.2022
- Author(s)
  北田研人，木戸口慧，中野大介，西山成．
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-18H03191
[Presentation] New salt concept and significance of MR inhibition2022
- Author(s)
  Nishiyama A.
- Organizer
  The 29th Scientific Meeting of the International Society of Hypertension.
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19712
[Presentation] Onco-Hypertension.2022
- Author(s)
  Akira Nishiyama
- Organizer
  International SHR meeting 2022
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24771
[Presentation] Klotho deficiency induces regulatory T cells in murine lupus nephritis.2022
- Author(s)
  Tsuneo Takenaka, Yishifumi Kurosaki, Naohito Ishii, Tsutomu Inoue, Akira Nishiyama
- Organizer
  Kidney Week 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08641
[Presentation] New salt concept and significance of MR inhibition.2022
- Author(s)
  Akira Nishiyama
- Organizer
  The 29th Scientific Meeting of the International Society of Hypertension.
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24771
[Presentation] New salt concept and significance of MR inhibition.2022
- Author(s)
  Akira Nishiyama
- Organizer
  The 29th Scientific Meeting of the International Society of Hypertension.
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K20664
[Presentation] KLOTHO SUPPLEMENTATION REVERSES RENAL DYSFUNCTION AND INTERSTITIAL FIBROSIS IN REMNANT KIDNEY2022
- Author(s)
  Tsuneo Takenaka, Arif Hasan, Takeshi Marumo, Tsutomu Inoue, Takashi Miyazaki, Hiromichi Suzuki, Yoshifumi Kurosaki, Naohito Ishii, Akira Nishiyama, Matsuihiko Hayashi
- Organizer
  ERA-EDTA Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08641
[Presentation] シン・ナトリウム調節2022
- Author(s)
  西山　成
- Organizer
  第52回日本腎臓学会西部学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-20K20664
[Presentation] 高血圧合併心不全ラットに対する新規の非ステロイド型MRブロッカーの薬効検討.2021
- Author(s)
  西山　成、澤野達哉、中野大介、北田研人、今村武史、ラフマンアサダ.
- Organizer
  第31回日本循環薬理学会
- Data Source
  KAKENHI-PROJECT-18H03191
[Presentation] 非侵襲血糖値センサを目指した非冷却マイクロボロメーターアレイセンサを用いた新たな中赤外パッシブ分光イメージングの提案2021
- Author(s)
  北崎友哉, 野郷孝介, 足立智, 岩城順也, 森本裕介, 宮村匡雅, 西山成, 和田健司, 石丸伊知郎
- Organizer
  Optics & Photonics Japan2021（OPJ2021）
- Data Source
  KAKENHI-PROJECT-18H01452
[Presentation] Effects of an SGLT2 inhibitor on salt sensitivity of blood pressure and sympathetic nerve activity in a non-diabetic rat model of chronic kidney disease.2021
- Author(s)
  Wan N, Rahman A, Nishiyama A.
- Organizer
  International Society of Hypertension.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K20664
[Presentation] Pathophysiological mechanism of mineralocorticoid receptor-dependent chronic kidney disease.2021
- Author(s)
  Nishiyama A.
- Organizer
  The 19th International Symposium on Atherosclerosis.
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K20664
[Presentation] クロト蛋白補充は腎亜全摘モデルにおける腎障害を抑制する2021
- Author(s)
  竹中　恒夫、井上　勉、西山　成、石井　直仁、林　松彦
- Organizer
  日本腎臓学会
- Data Source
  KAKENHI-PROJECT-20K08641
[Presentation] デキサメタゾンは皮膚のナトリウム・水分含量を減少させる.2021
- Author(s)
  北田研人. 森澤紀彦. 中野大介. Jens T. 西山成.
- Organizer
  第94回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-18H03191
[Presentation] 塩と病態生理・MR阻害薬,2020
- Author(s)
  西山　成，北田研人
- Organizer
  第63回日本糖尿病学会
- Invited
- Data Source
  KAKENHI-PROJECT-20K20664
[Presentation] 皮膚におけるナトリウム貯留と電解質調節2020
- Author(s)
  西山　成
- Organizer
  第63回日本腎臓学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-20K20664
[Presentation] New concept of salt and water balance2020
- Author(s)
  Akira Nishiyama
- Organizer
  第24回日本心血管内分泌代謝学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-18H03191
[Presentation] 塩と病態生理・MR阻害薬2020
- Author(s)
  西山　成
- Organizer
  第63回日本糖尿病学会シンポジウム
- Data Source
  KAKENHI-PROJECT-18H03191
[Presentation] 皮膚におけるナトリウム貯留と電解質調節2020
- Author(s)
  西山　成
- Organizer
  第63回日本腎臓学会学術総会シンポジウム
- Data Source
  KAKENHI-PROJECT-18H03191
[Presentation] DKD治療におけるRAS阻害剤とMR拮抗薬への期待2020
- Author(s)
  西山　成
- Organizer
  第35回日本糖尿病合併症学会
- Data Source
  KAKENHI-PROJECT-18H03191
[Presentation] クロト補充は多発性嚢胞腎モデルで血圧と腎機能を改善する2020
- Author(s)
  竹中恒夫, 小堀浩幸, 井上勉, 宮崎孝, 鈴木洋通, 西山成, 石井直仁, 林松彦
- Organizer
  日本腎臓学会学術集会
- Data Source
  KAKENHI-PROJECT-20K08641
[Presentation] New concept of salt and water balance2020
- Author(s)
  Akira Nishiyama
- Organizer
  CVMW2020心血管代謝週間（第28回日本血管生物医学会学術集会, 第24回日本心血管内分泌代謝学会学術総会, 第37回国際心臓研究学会日本部会, International Society for Applied Cardiovascular Biology (ISACB）
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K20664
[Presentation] （プロ）レニン受容体をターゲットとした癌に対する新規診断治療法の開発2020
- Author(s)
  西山　成
- Organizer
  第41回日本臨床薬理学会学術総会シンポジウム
- Data Source
  KAKENHI-PROJECT-18H03191
[Presentation] SGLT2阻害薬の腎保護作用のメカニズム2020
- Author(s)
  西山　成
- Organizer
  第84回日本循環器学会学術集会
- Data Source
  KAKENHI-PROJECT-18H03191
[Presentation] ミネラルコルチコイド受容体ブロッカー2020
- Author(s)
  西山　成
- Organizer
  第50回日本腎臓学会東部学術大会シンポジウム
- Data Source
  KAKENHI-PROJECT-18H03191
[Presentation] 食塩感受性高血圧の新しい機序2019
- Author(s)
  西山　成
- Organizer
  第42回日本高血圧学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-18H03191
[Presentation] Renoprotective effects of nonsteroidal MR blockers.2019
- Author(s)
  Nishiyama A.
- Organizer
  Asian Pacific Congress of Hypertension 2019.
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03191
[Presentation] Renal denervation attenuates a catabolic state in mice fed high salt2019
- Author(s)
  Yamazaki D, Kitada K, Morisawa N, Fujisawa Y, Nakano D, HItomi H, Titze J, Nishiyama A.
- Organizer
  Hypertension 2019 Scientific Sessions.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03191
[Presentation] Anemia Disrupts Renal Compensatory Responses After Uninephrectomy in Mice.2019
- Author(s)
  Nakano D, Nishiyama A.
- Organizer
  Annual Meetings of American Society of Nephrology.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03191
[Presentation] イヤリング型非侵襲血糖値センサーを目指した超音波アシスト中赤外フーリエ分光法2019
- Author(s)
  川嶋なつみ，北崎友哉，西山成，和田健司，石丸伊知郎
- Organizer
  2019年度精密工学会秋季大会学術講演会，L46，静岡，2019.09
- Data Source
  KAKENHI-PROJECT-18H01452
[Presentation] イヤリング型非侵襲血糖値センサーを目指した皮膚表層近傍における微弱な反射光検出が可能な高感度中赤外分光法2019
- Author(s)
  川嶋なつみ，北崎友哉，西山成，和田健司，石丸伊知郎，
- Organizer
  第4回黒潮カンファレンス，P37，沖縄，2019.11
- Data Source
  KAKENHI-PROJECT-18H01452
[Presentation] マルチスリット搭載型高感度中赤外ワンショットフーリエ分光器2019
- Author(s)
  川嶋なつみ，北崎友哉，西山成，和田健司，石丸伊知郎,
- Organizer
  Optics & Photonics Japan 2019, PDP3，大阪，2019.12
- Data Source
  KAKENHI-PROJECT-18H01452
[Presentation] Effects of the novel nonsteroidal mineralocorticoid receptor blocker, esaxerenone(CS-3150),on blood pressure and urinary angiotensinogen in low-renin dahl satl-sensitive hypertensive rats2019
- Author(s)
  Nishiyama A, Nakako D, Kobori H, Li L.
- Organizer
  World Congress of Nephrology. 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03191
[Presentation] Antiproliferative effects of monoclonal antibodies against (pro)renin receptor in pancreatic ductal adenocarcinoma.2019
- Author(s)
  Rahman A, Matsuyama M, Shibayama Y, Ebihara A, Nishiyama A.
- Organizer
  Hypertension 2019 Scientific Sessions.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03191
[Presentation] 食塩過剰摂取で生じるカタボリズム2019
- Author(s)
  西山　成
- Organizer
  第19回日本ＮＯ学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18H03191
[Presentation] High Salt Intake Induces Catabolism Accompanied　By Hepatic Urea Osmolyte Production And　Decreases Renal Sympathetic Nerve Activity2018
- Author(s)
  Morisawa N, Kitada K, Yamazaki D, Nakano D, Fujisawa Y, Nishiyama A.
- Organizer
  AHA Joint Hypertension 2018
- Data Source
  KAKENHI-PROJECT-18H03191
[Presentation] (Pro)renin Receptor Promotes Colorectal Cancer through the Wnt/Beta-Catenin Signaling Pathway despite Constitutive Pathway Component Mutations.2018
- Author(s)
  Nishiyama A, Shibayama Y, Wang J.
- Organizer
  AHA Joint Hypertension 2018
- Data Source
  KAKENHI-PROJECT-18H03191
[Presentation] Effects of a SGLT2　inhibitor on blood pressure and sympathetic nervous activity in salt-treated CKD rats.2018
- Author(s)
  Nakano D, Yifan Z, Nishiyama A
- Organizer
  Pulse of Asia 2018
- Data Source
  KAKENHI-PROJECT-18H03191
[Presentation] SGLT2阻害薬の腎循環・機能に及ぼす直接的な影響2017
- Author(s)
  西山　成、藤澤良秀、ラフマンアサダ、中野大介、人見浩史、北田研人、アンサリーチュバ
- Organizer
  第７回日本腎臓リハビリーテーション学会
- Place of Presentation
  筑波
- Year and Date
  2017-02-18
- Data Source
  KAKENHI-PROJECT-26460343
[Presentation] SGLT阻害薬は腎虚血再灌流後に生じる腎線維化の進展を抑制する2016
- Author(s)
  西山　成、張　一凡、人見浩史、中野大介
- Organizer
  第20回日本心血管内分泌代謝学会学術総会
- Place of Presentation
  東京
- Year and Date
  2016-12-15
- Data Source
  KAKENHI-PROJECT-26460343
[Presentation] Direct responses of tubular function to acute administration of SFLT2 inhibitor in anesthetized rats2016
- Author(s)
  西山　成、藤澤良秀、ラフマンアサダ、中野大介、人見浩史、北田研人、アンサリチュバ
- Organizer
  第20回日本心血管内分泌代謝学会学術総会
- Place of Presentation
  東京
- Year and Date
  2016-12-15
- Data Source
  KAKENHI-PROJECT-26460343
[Presentation] SGLT2阻害薬の利尿作用と降圧効果2016
- Author(s)
  西山　成、武重由衣、藤澤良秀、中野大介、人見浩史、Rahman　A.
- Organizer
  第16回日本抗加齢医学会総会
- Place of Presentation
  横浜
- Year and Date
  2016-06-10
- Data Source
  KAKENHI-PROJECT-26460343
[Presentation] 食塩感受性高血圧における腎内RASの役割2016
- Author(s)
  西山　成
- Organizer
  第39回日本高血圧学会総会
- Place of Presentation
  仙台
- Year and Date
  2016-09-30
- Invited
- Data Source
  KAKENHI-PROJECT-26460343
[Presentation] 18th International Congress on Nutrition and Metabolism in Renal Disease 20162016
- Author(s)
  Nishiyama A.
- Organizer
  Roles of Sympathetic Nerve and SGLT2 in the Development of Glucose Metabolism and Hypertension.
- Place of Presentation
  Naha
- Year and Date
  2016-04-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460343
[Presentation] Dipping pattern of blood pressure in Dahl salt-sensitive hypertensive rats during the progression of renal injury.2016
- Author(s)
  Sufin A, Fujisawa Y, Rahma A, Nakano D, Nishiyama A.
- Organizer
  The 17th International SHR Symposium
- Place of Presentation
  Tokyo
- Year and Date
  2016-09-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460343
[Presentation] SHR/NDmcr-cpにおけるSGLT2阻害薬の利尿作用と降圧効果2015
- Author(s)
  西山　成、藤澤良秀、中野大介、ラフマンアサダ
- Organizer
  第19回日本心血管内分泌代謝学会学術総会
- Place of Presentation
  神戸
- Year and Date
  2015-12-11
- Data Source
  KAKENHI-PROJECT-26460343
[Presentation] A sodium-glucose co-transporter 2 inhibitor prevents abnormality of circadian rhythm of blood pressure in salt-treated obese rats.2015
- Author(s)
  Nishiyama A, Nakano D, Ogata H, Takeshige Y
- Organizer
  American Heart Association Scientific Session
- Place of Presentation
  Orland
- Year and Date
  2015-11-10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460343
[Presentation] Effects of diuretics on SGLT2 inhibitor-induced changes in blood pressure and natriuresis in obese rats suffering from the metabolic syndrome.2015
- Author(s)
  Rahman A, Kittikulsuth W, Fujisawa Y, Hitomi H, Nakano D, Sohara E, Uchida S, Nishiyama A
- Organizer
  American Society of Nephrology
- Place of Presentation
  San Diego
- Year and Date
  2015-11-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460343
[Presentation] Changes in dipping pattern of blood pressure during the progression of renal injury in Dahl salt-sensitive hypertensive rats.2015
- Author(s)
  Sufiun A, Fujisawa Y, Rahman A, Nakano D, Hitomi H, Nishiyama A
- Organizer
  American Heart Association High Blood Pressure Council
- Place of Presentation
  Washington DC
- Year and Date
  2015-09-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460343
[Presentation] Effect of intravenous administration of a SGLT2 inhibitor on renal hemodynamics and functions in anesthetized rats.2015
- Author(s)
  Ansary TM、藤澤良秀、西山　成
- Organizer
  第58回日本腎臓学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2015-06-06
- Data Source
  KAKENHI-PROJECT-26460343
[Presentation] 腎交感神経を介した腎糖代謝連関；メタボリックシンドロームラットでの検討2014
- Author(s)
  西山　成、Asadur R、藤澤良秀、Sufiun A、小堀浩幸、Kazi R
- Organizer
  第125回日本薬理学会近畿部会
- Place of Presentation
  岡山
- Year and Date
  2014-06-20
- Data Source
  KAKENHI-PROJECT-12F02420
[Presentation] 補体C3は上皮間葉化(EMT)により腎尿細管でのレニン－アンジオテンシン(RA)系を活性化する2013
- Author(s)
  福田　昇、上野高浩、遠藤守人、松本紘一、相馬正義、西山　成
- Organizer
  第56回　日本腎臓学会
- Place of Presentation
  東京国際フォーラム（東京都千代田区）
- Data Source
  KAKENHI-PROJECT-24591242
[Presentation] Novel algorithm for background correctionof the quantitative spectroscopic tomography of the biogenic-substances2013
- Author(s)
  Praveen K.W. Abeygunawardhana,Wei Qi,Daisuke Kojima, Satoru Suzuki ,Akira Nishiyama,Ichirou Ishimaru
- Organizer
  SPIE BiOS
- Year and Date
  2013-02-21
- Data Source
  KAKENHI-PROJECT-22360165
[Presentation] 腎障害におけるレニン・アンジオテンシン・アルドステロン系の関与2013
- Author(s)
  西山　成
- Organizer
  第36回日本高血圧学会総会
- Place of Presentation
  大阪
- Invited
- Data Source
  KAKENHI-PROJECT-23590303
[Presentation] 日常生活空間で利用できる超小型ワンショット分光断層像計測装置(第二報)-高鮮明度化と高頑健性を保証する機能性共役面位相シフト格子法-2013
- Author(s)
  佐藤駿,藤原大,Kumara Praveen,鈴木聡,西山成,石丸伊知郎
- Organizer
  第60回応用物理学会春季学術講演会
- Year and Date
  2013-03-21
- Data Source
  KAKENHI-PROJECT-22360165
[Presentation] Quantitative Spectroscopic Tomography for Non-invasive Blood Glucose Concentration Measurement2013
- Author(s)
  Satoru Suzuki, Ryosuke Tsutsumi, Asuka Inui, Daisuke Kojima, Akira Nishiyama, and Ichiro Ishimaru
- Organizer
  International Symposium on Nonlinear Theory and its Applications
- Year and Date
  2013-02-22
- Data Source
  KAKENHI-PROJECT-22360165
[Presentation] ダール食塩感受性高血圧ラットで生じる腎組織障害は、減塩とARB・カルシウムチャネル拮抗薬併用による積極的な降圧で減退する2013
- Author(s)
  西山　成、ラフィーカジ、森川　貴、柴田幹子、岸田真嗣、濱田真宏、北林千津子、小西啓夫、今西政仁
- Organizer
  第49 回高血圧関連疾患モデル学会学術総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23590303
[Presentation] 2型糖尿病マウスにおけるCCBの降圧を介さないＡＲＢの脳腎保護効果の増強2013
- Author(s)
  西山　成、中野大介、人見浩史、小堀浩幸、Rafiq K
- Organizer
  第86回日本内分泌学会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-23590303
[Presentation] 補体C3は腎尿細管上皮間葉化(EMT)により腎内レニン・アンジオテンシン(RA)系を活性化する2013
- Author(s)
  福田　昇、上野高浩、松田裕之、西山　成、松本紘一、相馬正義
- Organizer
  第42回　日本心脈管作動物質学会
- Place of Presentation
  奈良
- Data Source
  KAKENHI-PROJECT-24591242
[Presentation] Renal sympahtetic denervation at a prediabetic stage suppresses insulin resistance in obese rats.2013
- Author(s)
  西山成, Rafiq K
- Organizer
  第61回日本心臓病学会学術集会
- Place of Presentation
  熊本市
- Year and Date
  2013-09-21
- Data Source
  KAKENHI-PROJECT-12F02420
[Presentation] RAASと腎障害2013
- Author(s)
  西山成, 小堀浩幸
- Organizer
  第86回日本内分泌学会
- Place of Presentation
  仙台
- Year and Date
  2013-04-26
- Data Source
  KAKENHI-PROJECT-23590303
[Presentation] Ｎ型カルシウムチャネルを介したアンジオテンシンIIによるポドサイト内カルシウムイオン変動の解析2013
- Author(s)
  中野大介、Liu　Y、人見浩史、小堀浩幸、西山　成
- Organizer
  第56回日本腎臓学会学術総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23590303
[Presentation] 日常生活空間で利用できる超小型ワンショット分光断層像計測装置(第一報) -透過型相対傾斜位相シフターによる実証実験-2013
- Author(s)
  藤原大,佐藤駿,鈴木聡, Kumara Praveen,西山成,石丸伊知郎
- Organizer
  第60回応用物理学会春季学術講演会
- Year and Date
  2013-03-21
- Data Source
  KAKENHI-PROJECT-22360165
[Presentation] 2型糖尿病マウスにおけるCCBの降圧を介さないARBの脳腎保護効果の増強2013
- Author(s)
  西山成、中野大介、人見浩史、小堀浩幸、Rafiq K
- Organizer
  第86回日本内分泌学会
- Place of Presentation
  仙台市
- Year and Date
  2013-04-26
- Data Source
  KAKENHI-PROJECT-12F02420
[Presentation] Renal sympathetic denervation at a prediabetic stage suppresses insulin resistance in OLETF rats2013
- Author(s)
  Rafiq K, Fujisawa Y, Rahman A, Suffin K, Nishiyama A
- Organizer
  第49回高血圧関連疾患モデル学会学術総会
- Place of Presentation
  東京
- Year and Date
  2013-09-07
- Data Source
  KAKENHI-PROJECT-12F02420
[Presentation] 補体C3は腎髄質上皮間葉化現象(EMT)により腎内レニン・アンジオテンシン(RA)系を活性化し高血圧およぎ腎硬化症を引き起こす2013
- Author(s)
  Zhou Xueli、福田　昇、上野高浩、遠藤守人、相馬正義、西山　成
- Organizer
  第49回　高血圧関連疾患モデル学会
- Place of Presentation
  日本大学会館（東京都千代田区）
- Data Source
  KAKENHI-PROJECT-24591242
[Presentation] 2型糖尿病マウスにおけるCCBの降圧を介さないARBの脳腎保護効果の増強2013
- Author(s)
  西山成, 中野大介, 人見浩史, 小堀浩幸, Rafiq K
- Organizer
  第86回日本内分泌学会
- Place of Presentation
  仙台
- Year and Date
  2013-04-26
- Data Source
  KAKENHI-PROJECT-23590303
[Presentation] 腎尿細管上皮間葉化による腎臓内レニン・アンジオテンシン系の亢進.2013
- Author(s)
  Zhou Xueli、福田　昇、上野高浩、相馬正義、西山　成
- Organizer
  第86回　日本内分泌学会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Data Source
  KAKENHI-PROJECT-24591242
[Presentation] Renal sympathetic deneravation suppresses de novo albuminuria in rats with aortic regurgitation2012
- Author(s)
  Nishiyama A
- Organizer
  24th Scientific Meeting of the International Society of Hypertension
- Place of Presentation
  シドニー市、オーストラリア
- Year and Date
  2012-10-01
- Data Source
  KAKENHI-PROJECT-12F02420
[Presentation] Quantitative Spectroscopic-tomography of Biological Membrane for the Non-invasive Blood Glucose Sensor2012
- Author(s)
  石丸伊知郎 ,西山成
- Organizer
  ISOT(International Symposium on Optomechatronic Technologies)2012
- Year and Date
  2012-10-20
- Data Source
  KAKENHI-PROJECT-22360165
[Presentation] Filtered Angiotensinogen, Not Renal Renin, Determines the Renal Angiotensin II Synthesis when Podocytes Lose Their Molecular Barrier Function.2012
- Author(s)
  Fumio Niimura, Akira Nishiyama, Iekuni Ichikawa, Taiji Matsusaka.
- Organizer
  ASN meeting 2012
- Place of Presentation
  San Diegoｺﾝﾍﾞﾝｼｮﾝｾﾝﾀｰ
- Data Source
  KAKENHI-PROJECT-22249033
[Presentation] The Phase and Amplitude Correction Algorithm for the Quantitative Spectroscopic Tomography of the Biogenic Substances2012
- Author(s)
  Pradeep K.W. Abeygunawardhana, Wei Qi,Satoru Suzuki , Ichiro Ishimaru,and Akira Nishiyama
- Organizer
  日本光学会 Optics & Photonics Japan 2012
- Year and Date
  2012-10-21
- Data Source
  KAKENHI-PROJECT-22360165
[Presentation] 近赤外分光法による温度変化に頑健なグルコース濃度推定法の提案2012
- Author(s)
  鈴木聡,堤良介,乾明日香,小島大輔,石田茜,西山成,石丸伊知郎
- Organizer
  電子・情報・システム部門大会
- Year and Date
  2012-09-21
- Data Source
  KAKENHI-PROJECT-22360165
[Presentation] アルドステロンにより老化した細胞はTNF-α発現および分泌の増大を介して近位尿細管細胞のアポトーシスを惹起する2012
- Author(s)
  北田研人, 中野大介, 人見浩史, 小堀浩幸, 西山成
- Organizer
  第49回日本臨床分子医学会学術集会
- Place of Presentation
  京都
- Year and Date
  2012-04-13
- Data Source
  KAKENHI-PROJECT-23590303
[Presentation] 共役面超解像格子によるフーリエ分光断層イメージングの高鮮明度化2012
- Author(s)
  鈴木陽,堤良介,QI Wei,小島大輔,佐藤駿,鈴木聡, Pradeep K.W.Abeygunawardhana,西山成,石丸伊知郎
- Organizer
  日本光学会Optics & Photonics Japan2012
- Year and Date
  2012-10-21
- Data Source
  KAKENHI-PROJECT-22360165
[Presentation] 食塩感受性高血圧で減塩治療しても蛋白尿が改善しないのは, 腎糸球体で生じる酸化ストレスが鉱質コルチコイド受容体を活性化するのが原因である(ラットによる検討)2012
- Author(s)
  西山成, 中野大介, Liu Y, 藤澤良秀, 人見浩史, 小堀浩幸, 北田研人
- Organizer
  第1回臨床高血圧フォーラム
- Place of Presentation
  大阪
- Year and Date
  2012-05-13
- Data Source
  KAKENHI-PROJECT-23590303
[Presentation] 補体C3による腎尿細管上皮間葉化(EMT)と腎内レニン-アンジオテンシン(RA)系の活性化2012
- Author(s)
  Zhou Xueli、福田　昇、上野高浩、松田裕之、西山　成、松本紘一、相馬正義
- Organizer
  第16回　心血管内分泌代謝学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24591242
[Presentation] 酸化ストレスは食塩感受性高血圧ラットの腎糸球体における鉱質コルチコイド受容体を活性化し、減塩により得られる蛋白尿抑制効果を減弱する2012
- Author(s)
  北田研人、中野大介、Liu Y、藤澤良秀、人見浩史、小堀浩幸、西山　成
- Organizer
  第49回日本臨床分子医学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23590303
[Presentation] 食塩感受性高血圧で減塩治療しても蛋白尿が改善しないのは、腎糸球体で生じる酸化ストレスが鉱質コルチコイド受容体を活性化するのが原因である（ラットによる検討）2012
- Author(s)
  西山　成、中野大介、LiuY、藤澤良秀、人見浩史、小堀浩幸、北田研人
- Organizer
  第1回臨床高血圧フォーラム
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23590303
[Presentation] アルドステロンにより老化した細胞はTNF-α分泌を介して近位尿細管細胞のアポトーシスを惹起する2012
- Author(s)
  北田研人、中野大介、谷田部淳一、人見浩史、小堀浩幸、西山　成
- Organizer
  第55回日本腎臓学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23590303
[Presentation] 腎内局所レニン・アンジオテンシン・アルドステロン系の病態への関与2012
- Author(s)
  西山成
- Organizer
  第55回日本腎臓学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2012-06-02
- Data Source
  KAKENHI-PROJECT-23590303
[Presentation] Liver-, but Not Kidney-Specific Angiotensinogen Gene Knockout Abrogates the Enhancement of Renal Angiotensin II Synthesis that Follows Podocyte Injury in Progressive Glomerulosclerosis2012
- Author(s)
  Taiji Matsusaka, Fumio Niimura, Masafumi Fukagawa, Akira Nishiyama, Iekuni Ichikawa.
- Organizer
  ASN meeting 2012
- Place of Presentation
  San Diegoｺﾝﾍﾞﾝｼｮﾝｾﾝﾀｰ
- Data Source
  KAKENHI-PROJECT-22249033
[Presentation] 腎尿細管上皮間葉化現象(EMT)による腎内レニン-アンジオテンシン(RA)系活性化―補体C3の関与―2012
- Author(s)
  Zhou Xueli、福田　昇、上野高浩、遠藤守人、松本紘一、相馬正義、西山　成
- Organizer
  第3回　腎不全研究会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24591242
[Presentation] Quantitative spectroscopic-tomography of biological tissues with near-infrared radiation for non-invasive measurement of the biogenic-substances2012
- Author(s)
  石丸伊知郎,西山成
- Organizer
  第二回日韓生体医用光学シンポジウム
- Year and Date
  2012-08-23
- Data Source
  KAKENHI-PROJECT-22360165
[Presentation] カード型相対傾斜位相シフターによる親指サイズのワンショット分光断層イメージングユニット2012
- Author(s)
  佐藤駿,QI Wei,鈴木聡,Pradeep K.W. Abeygunawardhana,西山成,石丸伊知郎
- Organizer
  日本光学会 Optics & Photonics Japan 2012
- Year and Date
  2012-10-21
- Data Source
  KAKENHI-PROJECT-22360165
[Presentation] 定量化フーリエ分光断層イメージングの ex-vivo による生体成分計測能力の実験的評価2012
- Author(s)
  QI Wei,堤良介,小島大輔,佐藤駿,石田茜,鈴木陽, Pradeep K.W.Abeygunawardhana,鈴木聡,西山成,石丸伊知郎
- Organizer
  日本光学会Optics& Photonics Japan 2012
- Year and Date
  2012-10-21
- Data Source
  KAKENHI-PROJECT-22360165
[Presentation] アンジオテンシンIIは内因性アルドステロン分泌の増加とは関係なく, 腎におけるP21発現を亢進する2011
- Author(s)
  中野大介, Bai L, Fan Y, 北田研人, 人見浩史, 西山成
- Organizer
  第34回日本高血圧学会
- Place of Presentation
  宇都宮
- Year and Date
  2011-10-21
- Data Source
  KAKENHI-PROJECT-23590303
[Presentation] 脳心腎関連における交感神経とレニン-アンジオテンシン-アルドステロン系の役割2011
- Author(s)
  西山成
- Organizer
  第84回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-03-23
- Data Source
  KAKENHI-PROJECT-20590253
[Presentation] 脳心腎関連における交感神経とレニン-アンジオテンシン-アルドステロン系の役割2011
- Author(s)
  西山成
- Organizer
  第84回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜(神奈川県)(招待講演)
- Year and Date
  2011-03-23
- Data Source
  KAKENHI-PROJECT-20590253
[Presentation] RAS阻害薬を使用した新しいコンセプトによるCKD治療戦略2010
- Author(s)
  西山成
- Organizer
  第31回日本臨床薬理学会年会
- Place of Presentation
  国立京都国際会館(京都府)(招待講演)
- Year and Date
  2010-12-02
- Data Source
  KAKENHI-PROJECT-20590253
[Presentation] 新しいコンセプトに基づいたRAS阻害薬による臓器保護戦略2010
- Author(s)
  西山成
- Organizer
  第218回日本循環器学会関東甲信越地方会
- Place of Presentation
  東京
- Year and Date
  2010-12-04
- Data Source
  KAKENHI-PROJECT-20590253
[Presentation] IgA腎症患者で発症する食塩感受性高血圧と腎内レニン・アンジオテンシン系2010
- Author(s)
  西山成
- Organizer
  第38回薬物活性シンポジウム
- Place of Presentation
  札幌
- Year and Date
  2010-11-12
- Data Source
  KAKENHI-PROJECT-20590253
[Presentation] Regression of superficial glomerular podocyte injury in type 2 diabetic rats with overt proteinuria : effect of angiotensin II blockade2010
- Author(s)
  西山成
- Organizer
  ISN Nexus
- Place of Presentation
  京都
- Year and Date
  2010-04-16
- Data Source
  KAKENHI-PROJECT-20590253
[Presentation] Intrarenal renin-angiotensin system and sodium sensitivity of blood pressure in patients with IGA nephropathy2010
- Author(s)
  西山成
- Organizer
  12th Asian Pacific Congress of Nephrology
- Place of Presentation
  Seoul, Korea
- Year and Date
  2010-06-06
- Data Source
  KAKENHI-PROJECT-20590253
[Presentation] RAAS and ROS-dependent renal injury2010
- Author(s)
  西山成
- Organizer
  The 6th International Conference on the Biology, Chemistry, and Therapeutic Applications of NitricOxide
- Place of Presentation
  京都
- Year and Date
  2010-06-14
- Data Source
  KAKENHI-PROJECT-20590253
[Presentation] Olmesartan ameliorates the impairment of renal function in aortic regulation model rats2010
- Author(s)
  西山成
- Organizer
  The 6th International Conference on the Biology, Chemistry, and Therapeutic Applications of NitricOxide
- Place of Presentation
  京都
- Year and Date
  2010-06-14
- Data Source
  KAKENHI-PROJECT-20590253
[Presentation] IgA腎症患者における尿中アンジオテンシノーゲン測定による、腎内レニン・アンジオテンシン系と食塩感受性高血圧との関連2010
- Author(s)
  西山成, 他
- Organizer
  第31回日本臨床薬理学会年会
- Place of Presentation
  国立京都国際会館(京都府)
- Year and Date
  2010-12-02
- Data Source
  KAKENHI-PROJECT-20590253
[Presentation] IgA腎症患者における尿中アンジオテンシノーゲン測定による、腎内レニン・アンジオテンシン系と食塩感受性高血圧との関連2010
- Author(s)
  西山成
- Organizer
  第31回日本臨床薬理学会年会
- Place of Presentation
  京都
- Year and Date
  2010-12-02
- Data Source
  KAKENHI-PROJECT-20590253
[Presentation] IgA腎症患者で発症する食塩感受性高血圧と腎内レニン・アンジオテンシン系2010
- Author(s)
  西山成, 他
- Organizer
  第38回薬物活性シンポジウム
- Place of Presentation
  札幌市教育文化会館(北海道)
- Year and Date
  2010-11-12
- Data Source
  KAKENHI-PROJECT-20590253
[Presentation] ダール食塩感受性高血圧ラットで生じる脳関門障害に対するオルメサルタンの効果2010
- Author(s)
  西山成
- Organizer
  第33回日本高血圧学会総会
- Place of Presentation
  静岡
- Year and Date
  2010-10-16
- Data Source
  KAKENHI-PROJECT-20590253
[Presentation] Sodium as a culprit for cardio-renal syndrome2010
- Author(s)
  西山成
- Organizer
  ISN Nexus
- Place of Presentation
  京都
- Year and Date
  2010-04-16
- Data Source
  KAKENHI-PROJECT-20590253
[Presentation] ダール食塩感受性高血圧ラットで生じる脳関門障害に対するオルメサルタンの効果2010
- Author(s)
  西山成, 他
- Organizer
  第33回日本高血圧学会総会
- Place of Presentation
  福岡国際会議場(福岡県)
- Year and Date
  2010-10-16
- Data Source
  KAKENHI-PROJECT-20590253
[Presentation] RAS阻害薬を使用した新しいコンセプトによるCKD治療戦略2010
- Author(s)
  西山成
- Organizer
  第31回日本臨床薬理学会年会
- Place of Presentation
  京都
- Year and Date
  2010-12-02
- Data Source
  KAKENHI-PROJECT-20590253
[Presentation] Possible mechanisms responsible for aldosterone and mineralocorticoid receptor-dependent renal injury2010
- Author(s)
  西山成
- Organizer
  The Third International Aldosterone Forum in Japan
- Place of Presentation
  東京
- Year and Date
  2010-05-15
- Data Source
  KAKENHI-PROJECT-20590253
[Presentation] Possible mechanisms responsible for aldosterone and mineralocorticoid receptor-dependent renal injury2010
- Author(s)
  Nishiyama A
- Organizer
  The Third International Aldosterone Forum in Japan
- Place of Presentation
  The Grand Hall(東京都)(招待講演)
- Year and Date
  2010-05-15
- Data Source
  KAKENHI-PROJECT-20590253
[Presentation] RAAS and ROS-dependent renal injury2010
- Author(s)
  Nishiyama A
- Organizer
  The 6th International Conference on the Biology, Chemistry, and Therapeutic Applications of Nitric Oxide
- Place of Presentation
  インターナショナルカンファレンスセンター(京都府)(招待講演)
- Year and Date
  2010-06-14
- Data Source
  KAKENHI-PROJECT-20590253
[Presentation] Regression of superficial glomerular podocytc injury in type 2diabetilrats with overt proteinuria : effect of angiotensin II blockade2010
- Author(s)
  Nishiyama A, et al.
- Organizer
  ISN Nexus
- Place of Presentation
  国立京都国際会館(京都府)
- Year and Date
  2010-04-16
- Data Source
  KAKENHI-PROJECT-20590253
[Presentation] Olmesartan ameliorates the impairment of renal function in aortic regulation model rats2010
- Author(s)
  Nishiyama A, et al.
- Organizer
  The 6th International Conference on the Biology, Chemistry, and Therapeutic Applications of Nitric Oxide
- Place of Presentation
  インターナショナルカンファレンスセンター(京都府)
- Year and Date
  2010-06-14
- Data Source
  KAKENHI-PROJECT-20590253
[Presentation] Sodium as a culprit for cardio-renal syndrome2010
- Author(s)
  Nishiyama A
- Organizer
  ISN Nexus
- Place of Presentation
  国立京都国際会館(京都府)(招待講演)
- Year and Date
  2010-04-16
- Data Source
  KAKENHI-PROJECT-20590253
[Presentation] 新しいコンセプトに基づいたRAS阻害薬による臓器保護戦略2010
- Author(s)
  西山成
- Organizer
  第218回日本循環器学会関東甲信越地方会
- Place of Presentation
  東京ステーションコンファレンス(東京都)(招待講演)
- Year and Date
  2010-12-04
- Data Source
  KAKENHI-PROJECT-20590253
[Presentation] Role of ARB on blood-brain barrier permeability and cognitive disorders in Dahl salt sensitive rats2009
- Author(s)
  Pelisch N, 細見直永, 上野正樹, 西山成, 河野雅和
- Organizer
  第34回日本脳卒中学会
- Place of Presentation
  松江
- Year and Date
  2009-03-22
- Data Source
  KAKENHI-PROJECT-18590945
[Presentation] Role of aldosterone in oxidative stress and renal injury2009
- Author(s)
  Akira Nishiyama
- Organizer
  World Congress of Nephrology
- Place of Presentation
  ミラノ市ミラノコンベンションセンター(イタリア)
- Data Source
  KAKENHI-PROJECT-20590253
[Presentation] Role of aldosterone in the pathogenesis of renal injury2009
- Author(s)
  Akira Nishiyama
- Organizer
  International Congress of Physiological Sciences
- Place of Presentation
  京都市京都国際会議場(日本)
- Data Source
  KAKENHI-PROJECT-20590253
[Presentation] 臓器保護薬としてのアルドステロン受容体格抗薬2009
- Author(s)
  西山成, 他
- Organizer
  第82回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-03-17
- Data Source
  KAKENHI-PROJECT-20590253
[Presentation] 尿中アンジオテンシノージェンはIgA腎症における腎内アンジオテンシン活性のマーカーとなる2009
- Author(s)
  西山成, 他
- Organizer
  第82回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-03-17
- Data Source
  KAKENHI-PROJECT-20590253
[Presentation] Urinary Angiotensin as a Biomarker for Intrarenal Angiotensin Activity in Patientu with lga Nephropathy : Effects of Antiotensin Blockade2009
- Author(s)
  Nishiyama A, et al.
- Organizer
  62nd High Blood Pressure Research Conference
- Place of Presentation
  Atlanta, Georgia U. S. A
- Year and Date
  2009-09-19
- Data Source
  KAKENHI-PROJECT-20590253
[Presentation] 尿中アンジオテンシノーゲンは腎内局所アンジオテンシン活性のバイオマーカーとなりうるか? 〜IgA腎症患者におけるARB投与での検討〜2009
- Author(s)
  西山成, 他
- Organizer
  第38回日本心脈管作動物質学会
- Place of Presentation
  岡山
- Year and Date
  2009-02-06
- Data Source
  KAKENHI-PROJECT-20590253
[Presentation] 局所脳虚血後における脳組織アンギオンテンシIIの変化2008
- Author(s)
  付華, 細見直永, Pelisch Nicolas, 劉鋼, 納谷貴之, 大北弘幸, 向井麻央, 西山成, 河野雅和
- Organizer
  第31回日本高血圧学会総会
- Place of Presentation
  札幌
- Year and Date
  2008-10-10
- Data Source
  KAKENHI-PROJECT-18590945
[Presentation] Role of candesartan in the regulatio of brain renin-angiotensin system2008
- Author(s)
  Pelisch N, 細見直永, 劉鋼, 大北弘幸, 納谷貴之, 向井麻央, 西山成, 河野雅和
- Organizer
  第20回日本脳循環代謝学会総会
- Place of Presentation
  東京
- Year and Date
  2008-11-06
- Data Source
  KAKENHI-PROJECT-18590945
[Presentation] Iga腎症患者における腎内RA系活性マーカーとしての尿中アンジオテンシノーゲンの測定とバルサルタンの効果2008
- Author(s)
  西山成, 他
- Organizer
  第12回日本心血管内分泌代謝学会学術総会
- Place of Presentation
  熊本
- Year and Date
  2008-11-28
- Data Source
  KAKENHI-PROJECT-20590253
[Presentation] Effects of angiotensin II stimulation of astrocytes2008
- Author(s)
  Hosomi N, Kobayashi S, Pelisch N, FuH, Liu G, Ohkita H, Naya T, Nishiyama A, Kohno M
- Organizer
  6th World Stroke Congress
- Place of Presentation
  ウィ-ン(オーストリア)
- Year and Date
  2008-09-25
- Data Source
  KAKENHI-PROJECT-18590945
[Presentation] Effects of Dual Blockade of Angiotensin II and Aldosterone on Renal Injury in Type 2 Diabetic Rats2008
- Author(s)
  Nishiyama A, et al
- Organizer
  62nd High Blood Pressure Research Conference
- Place of Presentation
  Atlanta, Georgia U. S. A
- Year and Date
  2008-09-19
- Data Source
  KAKENHI-PROJECT-20590253
[Presentation] Iga腎症における腎内RA系活性マーカーとしての尿中アンジオテンシンノーゲン2008
- Author(s)
  西山成, 他
- Organizer
  第29回日本臨床薬理学会年会
- Place of Presentation
  東京
- Year and Date
  2008-12-05
- Data Source
  KAKENHI-PROJECT-20590253
[Presentation] 顕性腎症を呈する2型糖尿病ラットで生じる表層・傍髄質糸球体上皮細胞障害と、オルメサルタンの保護効果2008
- Author(s)
  西山成, 他
- Organizer
  第31回日本高血圧学会総会
- Place of Presentation
  札幌
- Year and Date
  2008-10-10
- Data Source
  KAKENHI-PROJECT-20590253
[Presentation] Role of candesartan in the regulation of brain renin-angiotensin system2008
- Author(s)
  Pelisch N, Hosomi N, Kobayashi S, Fu H, Liu G, Ohkita H, Naya T, Miyake A, Ueno M, Nishiyama A, Kohno M
- Organizer
  6th World Stroke Congress
- Place of Presentation
  ウィ-ン(オーストリア)
- Year and Date
  2008-09-25
- Data Source
  KAKENHI-PROJECT-18590945
[Presentation] Brain angiotensin II regulaton with sysemic angiotenin type 1 receptor blocker.2008
- Author(s)
  Pelisch N, Hosomi N, Liu G, Fu H, Naya T, Ohkita H, Mukai M, Nishiyama A, Kohno M.
- Organizer
  Internonasymposiumfor the establishment of sustainable and recycling-based society
- Place of Presentation
  高松
- Year and Date
  2008-10-17
- Data Source
  KAKENHI-PROJECT-18590945
[Presentation] Role of candesartan in the regulationof bain renin-angotensin system2008
- Author(s)
  Pelisch N, Hosomi N, kobayashi S, Fu H Liu G, Ohkita H, Naya T, Mukai M, Ueno M, Miyatake A, Nishiyama A, Kohno M
- Organizer
  第31回日本高血圧学会総会
- Place of Presentation
  札幌
- Year and Date
  2008-10-10
- Data Source
  KAKENHI-PROJECT-18590945
[Presentation] Brain angiotensin II expresson increase following foal cerebral ischemia2008
- Author(s)
  Hosomi N, Fu H, Pelisch N, Liu G, Naya T, Ohkita H, Kobayashi S, Nishiyama A, Kohno M
- Organizer
  6th World Stroke Congress
- Place of Presentation
  ウィ-ン(オーストリア)
- Year and Date
  2008-09-25
- Data Source
  KAKENHI-PROJECT-18590945
[Presentation] Brain angiotensin II increasd following focal cerebral ischemia2008
- Author(s)
  Fu H, Hosomi N, Pelisch N, Liu G, Naya T, Ohkita H, Kobayashi H, Nishiyama A, Kohno M
- Organizer
  International symposium for the establishment of sustainable and recycling-based society
- Place of Presentation
  高松
- Year and Date
  2008-10-17
- Data Source
  KAKENHI-PROJECT-18590945
[Presentation] 顕性腎症を呈する2型糖尿病ラットで生じる表層・傍髄質糸球体上皮細胞障害と、オルメサルタンの保護効果2008
- Author(s)
  西山成, 他
- Organizer
  第12回日本心血管内分泌代謝学会学術総会
- Place of Presentation
  熊本
- Year and Date
  2008-11-28
- Data Source
  KAKENHI-PROJECT-20590253
[Presentation] 腎不全合併末梢循環不全におけるLDLアフェレシス療法の有効性と白血球NADPH oxidaseの関与2007
- Author(s)
  原大雅、清元秀泰、森脇久美子、西山成、近藤直樹、鵜川豊世武、人見浩史、松原啓介、伊原玄英、海部久美子、森諭史、東山智香子、岩崎憲泰、海部泰夫、岡本雅也、河野雅和
- Organizer
  第27回日本アフェレシス学会学術大会
- Place of Presentation
  横浜
- Year and Date
  2007-03-15
- Data Source
  KAKENHI-PROJECT-17590830
[Presentation] 酸化ストレスの評価方法と腎障害への応用酸化ストレスと腎障害2007
- Author(s)
  西山成、清元秀泰、小堀浩幸、河野雅和
- Organizer
  第50回日本腎臓学会学術総会
- Place of Presentation
  浜松
- Year and Date
  2007-06-08
- Data Source
  KAKENHI-PROJECT-17590830
[Presentation] 末梢循環不全合併透析患者に対するLDLアフェレシス療法の有用性-LDLアフェレシス療法による酸化ストレス軽減について-2006
- Author(s)
  原大雅、清元秀泰、森脇久美子、西山成、近藤直樹、鵜川豊世武、人見浩史、松原啓介、伊原玄英、海部久美子、森諭史、東山智香子、岩崎憲泰、海部泰夫、岡本雅也、河野雅和
- Organizer
  第26回日本アフェレシス学会学術大会
- Place of Presentation
  大津
- Year and Date
  2006-09-26
- Data Source
  KAKENHI-PROJECT-17590830
[Presentation] IFN-γによるヒトメサンギウム細胞のスーパーオキサイド産生系の検討2006
- Author(s)
  森脇久美子、清元秀泰、人見浩史、西山成、河野雅和
- Organizer
  第6回日本NO学会学術集会
- Place of Presentation
  東京
- Year and Date
  2006-09-16
- Data Source
  KAKENHI-PROJECT-17590830
[Presentation] 血液透析療法における酸化ストレスの産生と白血球NAD(P)H oxidaseコンポーネントp22phox遺伝子発現に関する検討2005
- Author(s)
  清元秀泰、森脇久美子、藤田昌子、マットルーブル・ラフマン、原大雅、近藤直樹、松向寺孝臣、鵜川豊世武、松原啓介、西山成、河野雅和
- Organizer
  第5回腎不全病態治療研究会
- Place of Presentation
  東京
- Year and Date
  2005-03-26
- Data Source
  KAKENHI-PROJECT-17590830
[Presentation] 末梢循環不全合併透析患者に対するLDLアフェレシス療法の有用性-LDLアフェレシス療法による酸化ストレス軽減について-2005
- Author(s)
  原大雅、清元秀泰、森脇久美子、近藤直樹、鵜川豊世武、人見浩史、松原啓介、伊原玄英、海部久美子、藤田昌子、西山成、森諭史、濱本有祐、佐野法久、東山智香子、松本恵子、森田順子、佐藤弘子、岩崎憲泰、小野茂男、海部泰夫、松本正義、嘉村智美、宮野恭匡
- Organizer
  第25回日本アフェレシス学会学術大会
- Place of Presentation
  奈良
- Year and Date
  2005-10-20
- Data Source
  KAKENHI-PROJECT-17590830
[Presentation] 末梢循環不全合併透析患者に対するLDLアフェレシス療法の有用性2005
- Author(s)
  原大雅、清元秀泰、森脇久美子、東山智香子、松本恵子、横山るみ子、佐藤弘子、岩崎泰憲、海部泰夫、宮野恭匡、近藤直樹、鵜川豊世武、松向寺孝臣、人見浩史、西山成、河野雅和
- Organizer
  第50回日本透析医学会学術集会
- Place of Presentation
  神奈川
- Year and Date
  2005-06-07
- Data Source
  KAKENHI-PROJECT-17590830
[Presentation] 血液透析療法にける酸化ストレスと白血球NAD(P)H oxidase p22phox遺伝子発現に関する検討2005
- Author(s)
  清元秀泰、森脇久美子、原大雅、伊原玄英、近藤直樹、松向寺孝臣、鵜川豊世武、松原啓介、人見浩史、西山成、河野雅和
- Organizer
  第48回日本腎臓学会総会
- Place of Presentation
  神奈川
- Year and Date
  2005-06-04
- Data Source
  KAKENHI-PROJECT-17590830
[Presentation] Renal sympathetic denervation improves glucose metabolism through an activation of sodium dependent glucose transporter 2 in type 2 diabetic rats
- Author(s)
  Nishiyama A, Fujisawa Y, Rahman A, Mogi M, Sufiun A, Rafiq K.
- Organizer
  International Society of Hypertension
- Place of Presentation
  Athens
- Year and Date
  2014-06-13 – 2014-06-16
- Data Source
  KAKENHI-PROJECT-12F02420
[Presentation] Effect of SGLT2 inhibitors on circadian blood pressure in metabolic syndrome.
- Author(s)
  Nishiyama A.
- Organizer
  ISN NEXUS Symposium Hypertension and Kidney
- Place of Presentation
  Brisbane
- Year and Date
  2014-09-26 – 2014-09-28
- Invited
- Data Source
  KAKENHI-PROJECT-26460343
[Presentation] Effects of renal sympathetic denervation on blood pressure and glucose metabolism in obese type 2 diabetic rats.
- Author(s)
  Rafiq K, Sherajee S, Fujisawa Y, Mogi M, Sufiun A, Rahman A, Nakano D, Koepsell H, Nishiyama A
- Organizer
  The 14th Asian Pacific Congress of Nephrology
- Place of Presentation
  Tokyo
- Year and Date
  2014-05-15 – 2014-05-17
- Data Source
  KAKENHI-PROJECT-12F02420
[Presentation] アンジオテンシンIIは内因性アルドステロン分泌の増加とは関係なく、腎におけるP21発現を亢進する
- Author(s)
  中野大介、Bai L、Fan Y、北田研人、人見浩史、西山　成
- Organizer
  第34回日本高血圧学会
- Place of Presentation
  宇都宮
- Data Source
  KAKENHI-PROJECT-23590303
[Presentation] 腎交感神経切除術はSGLT-2発現を抑制してメタボリックシンドロームでのインスリン抵抗性を改善する
- Author(s)
  西山　成、藤澤良秀、小堀浩幸、ラフィーカジ
- Organizer
  第3回臨床高血圧フォーラム
- Place of Presentation
  広島
- Year and Date
  2014-05-24 – 2014-05-26
- Data Source
  KAKENHI-PROJECT-12F02420
[Presentation] SGLT2阻害薬エンパグリフロジンは、メタボリックシンドロームラッットのdippingパターンの正常化を伴った降圧を示す
- Author(s)
  武重由依、藤澤良秀、Sufiun A、Asadur R、Rafiq K、中野大介、小堀浩幸、緒方浩顕、西山　成
- Organizer
  第37回日本高血圧学会総会
- Place of Presentation
  横浜
- Year and Date
  2014-10-17 – 2014-10-19
- Data Source
  KAKENHI-PROJECT-26460343
[Presentation] OLETFラットにおけるSGLT2阻害薬エンパグリフロジンの降圧作用
- Author(s)
  武重由依、藤澤良秀、Sufiun A、Asadur R、Rafiq K、中野大介、小堀浩幸、緒方浩顕、西山　成
- Organizer
  第57回日本腎臓学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-07-04 – 2014-07-06
- Data Source
  KAKENHI-PROJECT-26460343
[Presentation] SGLT2阻害薬は塩分負荷した肥満OLETEラットにおいてナトリウム利尿を伴った降圧を示す
- Author(s)
  武重由依、緒方浩顕、西山　成
- Organizer
  第44回日本心脈管作動物質学会
- Place of Presentation
  高松
- Year and Date
  2015-02-06 – 2015-02-07
- Data Source
  KAKENHI-PROJECT-26460343

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Nishiyama Akira 西山 成

NISHIYAMA Akira 西山 成

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過酷環境における「夏眠様反応」による体液制御法の開発Principal Investigator

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Glycobiology-based cellular slow cycling for the development of anti-ageing drugsPrincipal Investigator

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老化・加齢性疾患の予防に向けた「夏眠様反応」制御メカニズム解明のための基盤研究Principal Investigator

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Identification of aestivation-dependent longevity and its regulationPrincipal Investigator

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Kidney-mediated aging processPrincipal Investigator

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New therapeutic strategy for brain-cardiorenal-glucose metabolism syndrome: targeting on the sympathetic nervous system and SGLT2Principal Investigator

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脳心腎連関の病態における腎内アンジオテンシノーゲンの役割Principal Investigator

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Nishiyama Akira 西山成

NISHIYAMA Akira 西山成