YOKOSUKA Tadashi 横須賀忠

Researcher Number	10359599
Other IDs
External Links
Affiliation (Current)	2025: 東京医科大学, 医学部, 主任教授
Affiliation (based on the past Project Information) *help	2016 – 2024: 東京医科大学, 医学部, 主任教授 2015 – 2016: 東京医科大学, 医学部, 教授 2013 – 2014: 独立行政法人理化学研究所, 統合生命医科学研究センター, 上級研究員 2006 – 2012: 独立行政法人理化学研究所, 免疫シグナル研究グループ, 上級研究員 2004 – 2005: 独立行政法人理化学研究所, 免疫シグナル研究グループ, 研究員 2003: 千葉大学, 大学院・医学研究院, 助手
Review Section/Research Field	Principal Investigator Immunology / Biological Sciences / Basic Section 50020:Tumor diagnostics and therapeutics-related / Transformative Research Areas, Section (III) / Medium-sized Section 49:Pathology, infection/immunology, and related fields / Tumor therapeutics Except Principal Investigator Biological Sciences / Basic Section 54010:Hematology and medical oncology-related / Immunology
Keywords	Principal Investigator シグナル伝達 / 免疫学 / 分子イメージング / 免疫シナプス / マイクロクラスター / シグナル伝達分子 / キメラ抗原受容体 / CAR-T細胞 / 免疫チェックポイント / T細胞受容体 … More / イメージング / 細胞療法 / T細胞 / MHC / 獲得免疫 / 受容体・細胞内シグナル伝達 / バイオイメージング / リンパ球 / 抗原認識 / 補助刺激受容体 / SMAC / プレイナーメンブラン / シグナルソーム / T細胞活性化 / Tリンパ球 / ICOS / 2B4 / T細胞補助刺激受容体 / 共受容体 / 自己抗原 / T細胞補助シグナル / T細胞疲弊 / 免疫チェックポイント分子 / TIGIT / シグナロソーム / 副刺激受容体 / 腫瘍免疫 / T細胞シグナル / キメラ抗原受容体T細胞 / がん免疫 / 自己免疫疾患 / 抗リン脂質抗体症候群 / TCR / 超解像イメージング / ミスフォールド蛋白質 / 自己抗体 / HLA / ネオ・セルフ / 癌 / エフェクター / 細胞傷害性T細胞 / T細胞受容体シグナル / ホメオスタシス増殖 / サイトカインシグナル / 分化誘導 / 細胞分裂 / 細胞傷害活性 / キラーT細胞 … More Except Principal Investigator 免疫学的自己 / ネオ・セルフ / 分子イメージング / BiTE抗体療法 / hCD3 / hCD19 / サイトカイン産生 / 腫瘍殺傷能力 / effector T細胞 / TCRマイクロクラスター / BiTE / 成果とりまとめ / 国際研究協力 / 免疫認識機構 / T細胞抗原受容体 / HLA / バイオリソース / 国際共同研究 / 国際活動支援 / 構造生物学 / アレルギー / MHC / 自己免疫疾患 / 連携強化 / 免疫的自己 / 抗原認識機構 / 研究支援 / 総括班 / イメージング / 免疫学 / T細胞活性化 / 獲得免疫 / TCR複合体 / イメージング解析 / ミクロチューブル / 細胞骨格 / ダイニン / PD-i / 活性化シグナル / 副刺激 / 細胞活性化 / T細胞 / 抗原認識 / シグナル伝達 / ミクロクラスター / 免疫シナプス Less

Benefits of endogenous TCRs recognizing self antigens in CAR-T cell funcitonsPrincipal Investigator
- Principal Investigator
  
  横須賀忠
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Tokyo Medical University
Development of the basis of the crosstalk between T cell costimulatory receptors and chimeric antigen receptorsPrincipal Investigator
- Principal Investigator
  
  横須賀忠
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Tokyo Medical University
先端的分子イメージング法を基盤としたBiTE抗体療法の解析
- Principal Investigator
  
  西嶋仁
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Tokyo Medical University
ネオ・セルフの生成・機能・構造
- Principal Investigator
  
  松本満
- Project Period (FY)
  2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokushima
Molecualr imaging for development of chimeric antigen receptors (CARs) resistant to T cell exhaustionPrincipal Investigator
- Principal Investigator
  
  Yokosuka Tadashi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Tokyo Medical University
Signalosome formation and functions of the immune-checkpoint receptor TIGIT regulated by the height of its ectodomain.Principal Investigator
- Principal Investigator
  
  Yokosuka Tadashi
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 49:Pathology, infection/immunology, and related fields
- Research Institution
  Tokyo Medical University
Basic research for the development of a novel CAR-adaptor T cells by an advanced imaging systemPrincipal Investigator
- Principal Investigator
  
  Yokosuka Tadashi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Tumor therapeutics
- Research Institution
  Tokyo Medical University
Comprehensive understanding of neo-self generation, function, and structure
- Principal Investigator
  
  MATSUMOTO Mitsuru
- Project Period (FY)
  2016 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokushima
Analysis for neo-self in MHC-misfolded protein complexPrincipal Investigator
- Principal Investigator
  
  Yokosuka Tadashi
- Project Period (FY)
  2016 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical University
International support for the reseach activities for the production, function and structure of neo-self
- Principal Investigator
  
  MATSUMOTO Mitsuru
- Project Period (FY)
  2016 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokushima
ユビキチンが形成するT細胞抑制性シグナルソームの分子イメージング解析Principal Investigator
- Principal Investigator
  
  横須賀忠
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical University
E3ユビキチンリガーゼの機能ドメイン形成によるT細胞活性化制御機構の解明Principal Investigator
- Principal Investigator
  
  横須賀忠
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  The Institute of Physical and Chemical Research
Mechanism of T cell activation regulation by TCR microclusters and the costimulation network.Principal Investigator
- Principal Investigator
  
  Yokosuka Tadashi
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Tokyo Medical University
  The Institute of Physical and Chemical Research
ユビキチン化と抑制性マイクロクラスターの分子イメージング解析Principal Investigator
- Principal Investigator
  
  横須賀忠
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  The Institute of Physical and Chemical Research
Mechanisms of T cell activation regulation by inhibitory microclustersPrincipal Investigator
- Principal Investigator
  
  YOKOSUKA Tadashi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  The Institute of Physical and Chemical Research
Spatiotemporal regulation of antigen recognition and activation of T cells
- Principal Investigator
  
  SAITO Takashi
- Project Period (FY)
  2007 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Immunology
- Research Institution
  The Institute of Physical and Chemical Research
Positive and negative regulation of T-cell activation by costimulatory molecules through TCR microclustersPrincipal Investigator
- Principal Investigator
  
  YOKOSUKA Tadashi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  The Institute of Physical and Chemical Research
プレーナーメンブランを用いた細胞傷害性T細胞の自己認識機構の解明Principal Investigator
- Principal Investigator
  
  横須賀忠
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Immunology
- Research Institution
  The Institute of Physical and Chemical Research
細胞増殖を伴わないキラーT細胞の機能分化のメカニズムPrincipal Investigator
- Principal Investigator
  
  横須賀忠
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Immunology
- Research Institution
  The Institute of Physical and Chemical Research
  Chiba University

[Book] Basic Immunology and Its Clinical Application2024
- Author(s)
  Nishi Wataru, Ei Wakamatsu, Hiroaki Machiyama, Ryohei Matsushima, Yosuke Yoshida, Tetsushi Nishikawa, Hiroko Toyota, Masae Furuhata, Hitoshi Nishijima, Arata Takeuchi, Makoto Suzuki, Tadashi Yokosuka
- Total Pages
  258
- Publisher
  Springer
- Data Source
  KAKENHI-PUBLICLY-23H04790
[Book] Basic Immunology and Its Clinical Application2024
- Author(s)
  Nishi Wataru, Ei Wakamatsu, Hiroaki Machiyama, Ryohei Matsushima, Yosuke Yoshida, Tetsushi Nishikawa, Hiroko Toyota, Masae Furuhata, Hitoshi Nishijima, Arata Takeuchi, Makoto Suzuki, Tadashi Yokosuka
- Total Pages
  258
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-23K27466
[Book] 腫瘍内科2022
- Author(s)
  横須賀忠、若松英、西嶋仁、西航、松島遼平、西川哲史、町山裕亮、竹内新
- Total Pages
  139
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-20H03536
[Book] 腫瘍内科2022
- Author(s)
  横須賀忠、若松英、西嶋仁、西航、松島遼平、西川哲史、町山裕亮、竹内新
- Total Pages
  139
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-19K22545
[Book] Precision Medicine2022
- Author(s)
  横須賀忠、若松英、西嶋仁、竹内新、町山裕亮
- Total Pages
  90
- Publisher
  北隆館
- Data Source
  KAKENHI-PROJECT-19K22545
[Book] Precision Medicine2022
- Author(s)
  横須賀忠、若松英、西嶋仁、竹内新、町山裕亮
- Total Pages
  90
- Publisher
  北隆館
- Data Source
  KAKENHI-PROJECT-20H03536
[Book] 標準免疫学第4版2021
- Author(s)
  横須賀忠
- Total Pages
  416
- Publisher
  医学書院
- ISBN
  9784758103909
- Data Source
  KAKENHI-PROJECT-20H03536
[Book] 標準免疫学第4版2021
- Author(s)
  横須賀忠
- Total Pages
  12
- Publisher
  医学書院
- Data Source
  KAKENHI-INTERNATIONAL-16K21731
[Book] 標準免疫学第4版2021
- Author(s)
  横須賀忠
- Total Pages
  416
- Publisher
  医学書院
- ISBN
  9784758103909
- Data Source
  KAKENHI-PROJECT-19K22545
[Book] 標準免疫学第4版2021
- Author(s)
  横須賀忠
- Total Pages
  434
- Publisher
  医学書院
- ISBN
  9784260042383
- Data Source
  KAKENHI-PLANNED-16H06501
[Book] 実験医学増刊号「新規の創薬モダリティ」細胞医薬2020
- Author(s)
  横須賀忠, 若松英, 西嶋仁, 竹原朋宏, 西航, 塚本昌子, 町山裕亮
- Total Pages
  243
- Publisher
  羊土社
- ISBN
  9784758103909
- Data Source
  KAKENHI-PLANNED-16H06501
[Book] 実験医学増刊号「新規の創薬モダリティ　細胞医薬」2020
- Author(s)
  横須賀忠, 若松英, 西嶋仁, 竹原朋宏, 西航, 塚本昌子, 町山裕亮
- Total Pages
  241
- Publisher
  羊土社
- ISBN
  9784260042383
- Data Source
  KAKENHI-PROJECT-20H03536
[Book] 「膜タンパク質工学ハンドブック」第7章第2節免疫チェックポイント受容体PD-1とCTLA-42020
- Author(s)
  横須賀忠、若松英、町山裕亮
- Total Pages
  624
- Publisher
  株NTS
- ISBN
- Data Source
  KAKENHI-PLANNED-16H06501
[Book] 「膜タンパク質工学ハンドブック」第7章第2節免疫チェックポイント受容体PD-1とCTLA-42020
- Author(s)
  横須賀忠、若松英、町山裕亮
- Total Pages
  624
- Publisher
  株NTS
- ISBN
- Data Source
  KAKENHI-PROJECT-19K22545
[Book] 実験医学増刊号「新規の創薬モダリティ　細胞医薬」2020
- Author(s)
  横須賀忠, 若松英, 西嶋仁, 竹原朋宏, 西航, 塚本昌子, 町山裕亮
- Total Pages
  241
- Publisher
  羊土社
- ISBN
  9784260042383
- Data Source
  KAKENHI-PROJECT-19K22545
[Book] 「膜タンパク質工学ハンドブック」第7章第2節免疫チェックポイント受容体PD-1とCTLA-42020
- Author(s)
  横須賀忠、若松英、町山裕亮
- Total Pages
  624
- Publisher
  株NTS
- ISBN
  9784860435370
- Data Source
  KAKENHI-PROJECT-17H03600
[Book] 「膜タンパク質工学ハンドブック」第7章第2節免疫チェックポイント受容体PD-1とCTLA-42019
- Author(s)
  横須賀忠、若松英、町山裕亮
- Total Pages
  624
- Publisher
  （株）NTS
- Data Source
  KAKENHI-ORGANIZER-16H06495
[Book] 実験医学増刊号「新・腫瘍免疫学」免疫チェックポイント分子の分子作用機序2019
- Author(s)
  横須賀忠、若松英、秦喜久美、竹原朋宏、西航、矢那瀬紀子、町山裕亮
- Total Pages
  268
- Publisher
  羊土社
- ISBN
  9784758103817
- Data Source
  KAKENHI-PROJECT-17H03600
[Book] 実験医学増刊号「新・腫瘍免疫学」免疫チェックポイント分子の分子作用機序2019
- Author(s)
  横須賀忠、若松英、秦喜久美、竹原朋宏、西航、矢那瀬紀子、町山裕亮
- Total Pages
  268
- Publisher
  羊土社
- ISBN
  9784758103817
- Data Source
  KAKENHI-PROJECT-19K22545
[Book] 「膜タンパク質工学ハンドブック」第7章第2節免疫チェックポイント受容体PD-1とCTLA-42019
- Author(s)
  横須賀忠、若松英、町山裕亮
- Total Pages
  624
- Publisher
  （株）NTS
- Data Source
  KAKENHI-INTERNATIONAL-16K21731
[Book] 実験医学増刊号「新・腫瘍免疫学」免疫チェックポイント分子の分子作用機序2019
- Author(s)
  横須賀忠、若松英、秦喜久美、竹原朋宏、西航、矢那瀬紀子、町山裕亮
- Total Pages
  268
- Publisher
  羊土社
- Data Source
  KAKENHI-INTERNATIONAL-16K21731
[Book] Janeway's免疫生物学原著第9版第7章リンパ球レセプターシグナル2019
- Author(s)
  横須賀忠、監訳：笹月健彦、吉開泰信
- Total Pages
  884
- Publisher
  南江堂
- ISBN
  9784524251155
- Data Source
  KAKENHI-PROJECT-17H03600
[Book] Janeway's免疫生物学原著第9版第7章リンパ球レセプターシグナル2019
- Author(s)
  横須賀忠、西川博嘉
- Total Pages
  884
- Publisher
  南江堂
- Data Source
  KAKENHI-ORGANIZER-16H06495
[Book] Janeway's免疫生物学原著第9版第7章リンパ球レセプターシグナル2019
- Author(s)
  横須賀忠、監訳：笹月健彦、吉開泰信
- Total Pages
  884
- Publisher
  南江堂
- ISBN
  9784524251155
- Data Source
  KAKENHI-PLANNED-16H06501
[Book] 実験医学増刊号「新・腫瘍免疫学」免疫チェックポイント分子の分子作用機序2019
- Author(s)
  横須賀忠、若松英、秦喜久美、竹原朋宏、西航、矢那瀬紀子、町山裕亮
- Total Pages
  268
- Publisher
  羊土社
- ISBN
  9784758103817
- Data Source
  KAKENHI-PLANNED-16H06501
[Book] Janeway's免疫生物学原著第9版第7章リンパ球レセプターシグナル2019
- Author(s)
  横須賀忠、西川博嘉
- Total Pages
  884
- Publisher
  南江堂
- Data Source
  KAKENHI-INTERNATIONAL-16K21731
[Book] 実験医学増刊号「新・腫瘍免疫学」免疫チェックポイント分子の分子作用機序2019
- Author(s)
  横須賀忠、若松英、秦喜久美、竹原朋宏、西航、矢那瀬紀子、町山裕亮
- Total Pages
  268
- Publisher
  羊土社
- Data Source
  KAKENHI-ORGANIZER-16H06495
[Book] 実験医学すべてはここから始まった、CTLA-42018
- Author(s)
  横須賀忠、若松英、古畑昌枝、豊田博子、秦喜久美、矢那瀬紀子、町山裕亮
- Total Pages
  138
- Publisher
  羊土社
- ISBN
- Data Source
  KAKENHI-PROJECT-17H03600
[Book] 東邦医学会雑誌分子イメージングが拓く免疫チェックポイント受容体のT細胞活性化制御機構2018
- Author(s)
  横須賀忠、若松英、秦喜久美、矢那瀬紀子、竹原朋宏、町山裕亮
- Total Pages
  22
- Publisher
  東邦医学会雑誌編集事務局
- ISBN
- Data Source
  KAKENHI-PLANNED-16H06501
[Book] 東邦医学会雑誌分子イメージングが拓く免疫チェックポイント受容体のT細胞活性化制御機構2018
- Author(s)
  横須賀忠、若松英、秦喜久美、矢那瀬紀子、竹原朋宏、町山裕亮
- Total Pages
  22
- Publisher
  東邦医学会雑誌編集事務局
- ISBN
- Data Source
  KAKENHI-PROJECT-17H03600
[Book] 臨床免疫・アレルギー科　分子イメージングから考察した免疫チェックポイント分子のT細胞抑制機構2018
- Author(s)
  横須賀忠、若松英、古畑昌枝、豊田博子、秦喜久美、矢那瀬紀子、町山裕亮
- Total Pages
  119
- Publisher
  科学評論社
- ISBN
- Data Source
  KAKENHI-PROJECT-17H03600
[Book] 生物物理2018
- Author(s)
  横須賀忠、若松英、矢那瀬紀子、秦喜久美、町山裕亮
- Total Pages
  64
- Publisher
  日本生物物理学会
- ISBN
- Data Source
  KAKENHI-PLANNED-16H06501
[Book] アバスーリックマンーピレ分子細胞免疫学原著歳9版第7章免疫受容体とシグナル伝達2018
- Author(s)
  横須賀忠、監訳：中尾篤人
- Total Pages
  577
- Publisher
  エルゼビア・ジャパン
- ISBN
  9784860349172
- Data Source
  KAKENHI-PLANNED-16H06501
[Book] アバスーリックマンーピレ分子細胞免疫学原著歳9版第7章免疫受容体とシグナル伝達2018
- Author(s)
  横須賀忠、監訳：中尾篤人
- Total Pages
  577
- Publisher
  エルゼビア・ジャパン
- ISBN
  9784860349172
- Data Source
  KAKENHI-PROJECT-17H03600
[Book] 実験医学すべてはここから始まった、CTLA-42018
- Author(s)
  横須賀忠、若松英、古畑昌枝、豊田博子、秦喜久美、矢那瀬紀子、町山裕亮
- Total Pages
  138
- Publisher
  羊土社
- ISBN
- Data Source
  KAKENHI-PLANNED-16H06501
[Book] 臨床免疫・アレルギー科　分子イメージングから考察した免疫チェックポイント分子のT細胞抑制機構2018
- Author(s)
  横須賀忠、若松英、古畑昌枝、豊田博子、秦喜久美、矢那瀬紀子、町山裕亮
- Total Pages
  119
- Publisher
  科学評論社
- ISBN
- Data Source
  KAKENHI-PLANNED-16H06501
[Book] 生物物理2018
- Author(s)
  横須賀忠、若松英、矢那瀬紀子、秦喜久美、町山裕亮
- Total Pages
  64
- Publisher
  日本生物物理学会
- ISBN
- Data Source
  KAKENHI-PROJECT-17H03600
[Book] 臨床免疫・アレルギー科　細胞膜脂質成分によるT細胞シグナルソームと活性化の制御機構2017
- Author(s)
  横須賀忠、古畑昌枝、豊田博子、秦喜久美、矢那瀬紀子、町山裕亮
- Total Pages
  102
- Publisher
  科学評論社
- Data Source
  KAKENHI-PLANNED-16H06501
[Book] 臨床免疫・アレルギー科　最先端イメージング技術によるTCRシグナル研究の進歩2016
- Author(s)
  横須賀忠、古畑昌枝、豊田博子、秦喜久美、矢那瀬紀子、町山裕亮
- Total Pages
  104
- Publisher
  科学評論社
- Data Source
  KAKENHI-PLANNED-16H06501
[Book] CTLA-4によるT細胞活性化制御の分子機序,臨床免疫・アレルギー科2012
- Author(s)
  横須賀忠
- Data Source
  KAKENHI-PROJECT-21590548
[Book] 免疫の辞典2011
- Author(s)
  横須賀忠
- Publisher
  朝倉書店
- Data Source
  KAKENHI-PUBLICLY-23113521
[Book] 免疫の辞典2011
- Author(s)
  横須賀忠
- Publisher
  朝倉書店
- Data Source
  KAKENHI-PROJECT-21590548
[Book] Curr.Top.Microbiol.Immunol. (T. Saito and F. D. Batista (eds.), The immunological synapse, TCR microclusters, and T cell activation.)2010
- Author(s)
  Yokosuka T, Saito T.
- Publisher
  Springer-Verlag
- Data Source
  KAKENHI-PROJECT-19109005
[Book] T細胞の活性化に対する補助刺激受容体CTLA-4による時空間的な制御機構の解明2010
- Author(s)
  横須賀忠、斉藤隆
- Publisher
  ライフサイエンス新着論文レビュー
- Data Source
  KAKENHI-PROJECT-21590548
[Book] The immunological synapse, TCR microclusters, and T cell activation2010
- Author(s)
  Yokosuka T and Saito T.
- Publisher
  Springer-Verlag Berlin Heidelberg
- Data Source
  KAKENHI-PROJECT-19109005
[Book] The immunological synapse, TCR microclusters, and T cell activation2010
- Author(s)
  Yokosuka T, Saito T.
- Publisher
  Springer-Verlag Berlin Heidelberg
- Data Source
  KAKENHI-PROJECT-21590548
[Book] T細胞活性化時のTCRとシグナル伝達分子の動態:臨床免疫・アレルギー科50巻3号 2008年9月号2008
- Author(s)
  横須賀忠
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-19590504
[Book] T細胞受容体マイクロクラスター-T細胞活性化を制御するシグナルソームの発見-:感染炎症免疫37巻2号2007
- Author(s)
  横須賀忠
- Publisher
  医薬の門社
- Data Source
  KAKENHI-PROJECT-19590504
[Book] 免疫シナプスを構成するTCRマイクロクラスターと T 細胞活性化機構:Annual Review 2008 2007年11月20日2007
- Author(s)
  横須賀忠
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-19590504
[Book] 実験医学2006
- Author(s)
  横須賀忠
- Total Pages
  3
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-17790330
[Book] シグナル伝達病を知るーその分子機序解明から新たな治療戦略までー(遺伝子医学MOOK6)2006
- Author(s)
  横須賀忠
- Total Pages
  328
- Publisher
  メディカルドゥ
- Data Source
  KAKENHI-PROJECT-17790330
[Journal Article] Evaluation of therapeutic PD-1 antibodies by an advanced single-molecule imaging system detecting human PD-1 microclusters2023
- Author(s)
  Nishi Wataru、Wakamatsu Ei、Machiyama Hiroaki、Matsushima Ryohei、Saito Kensho、Yoshida Yosuke、Nishikawa Tetsushi、Takehara Tomohiro、Toyota Hiroko、Furuhata Masae、Nishijima Hitoshi、Takeuchi Arata、Azuma Miyuki、Suzuki Makoto、Yokosuka Tadashi
- Journal Title
  
  Nature Communications
  
  Volume: 14 Issue: 1 Pages: 1-16
- DOI
  10.1038/s41467-023-38512-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07124, KAKENHI-PROJECT-22K07261, KAKENHI-PROJECT-22K08487, KAKENHI-PUBLICLY-23H04790, KAKENHI-PROJECT-23K27466
[Journal Article] Evaluation of therapeutic PD-1 antibodies by an advanced single-molecule imaging system detecting human PD-1 microclusters2023
- Author(s)
  Nishi W, Wakamatsu E, Machiyama H, Matsushima R, Saito K, Yoshida Y, Nishikawa T, Takehara T, Toyota H, Furuhata M, Nishijima H, Takeuchi A, Azuma M, Suzuki M, Yokosuka T
- Journal Title
  
  Nature Communications
  
  Volume: -
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-INTERNATIONAL-16K21731
[Journal Article] PD-L2 suppresses T cell signaling via coinhibitory microcluster formation and SHP2 phosphatase recruitment2021
- Author(s)
  Tomohiro Takehara, Ei Wakamatsu, Hiroaki Machiyama, Wataru Nishi, Katsura Emoto, Miyuki Azuma, Kenzo Soejima, Koichi Fukunaga, Tadashi Yokosuka
- Journal Title
  
  Communications Biology
  
  Volume: 4 Issue: 1 Pages: 1-12
- DOI
  10.1038/s42003-021-02111-3
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22545, KAKENHI-PROJECT-20J10564, KAKENHI-PROJECT-18K06165, KAKENHI-ORGANIZER-16H06495, KAKENHI-WRAPUP-21H00461, KAKENHI-PROJECT-19H03671, KAKENHI-PROJECT-19K07718, KAKENHI-INTERNATIONAL-16K21731, KAKENHI-PROJECT-20H03536
[Journal Article] 受容体シグナルの「デザイン」を評価するイメージング技術～脂質二重支持膜～2020
- Author(s)
  横須賀忠，若松英，西嶋仁，竹原朋宏，西航，塚本昌子，町山裕亮
- Journal Title
  
  実験医学増刊号「新規の創薬モダリティ　細胞医薬」
  
  Volume: 1 Pages: 64-70
- Data Source
  KAKENHI-INTERNATIONAL-16K21731
[Journal Article] Inhibition of T cell activation and function by the adaptor protein CIN85.2019
- Author(s)
  Kong Mei S*., Hashimoto-Tane A*., Kawashima Y., Sakuma M., Yokosuka T., Kometani K., Onishi R., Carpino N., Ohara O., Kurosaki T., Phua K.K. and Saito, T.
- Journal Title
  
  Science Signaling
  
  Volume: 12 Issue: 567 Pages: 1609-1625
- DOI
  10.1126/scisignal.aav4373
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19576, KAKENHI-PROJECT-18K19447, KAKENHI-INTERNATIONAL-16K21731, KAKENHI-ORGANIZER-16H06495, KAKENHI-PLANNED-16H06501, KAKENHI-PUBLICLY-17H05806, KAKENHI-PROJECT-26221306, KAKENHI-PROJECT-17H03600, KAKENHI-PROJECT-18H02672, KAKENHI-PROJECT-16K08851
[Journal Article] 細胞膜脂質成分によるT細胞シグナルソームと活性化の制御機構2017
- Author(s)
  横須賀忠、古畑昌枝、豊田博子、秦喜久美、矢那瀬紀子、町山裕亮
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 67 Pages: 321-326
- NAID
  40021132650
- Data Source
  KAKENHI-ORGANIZER-16H06495
[Journal Article] Analyzing the Dynamics of Signaling Microclusters2017
- Author(s)
  Hashimoto-Tane A, Yokosuka T, Saito T.
- Journal Title
  
  The Immune Synapse
  
  Volume: 1584 Pages: 5-64
- DOI
  10.1007/978-1-4939-6881-7_4
- ISBN
  9781493968794, 9781493968817
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06501, KAKENHI-PROJECT-16K08851, KAKENHI-PROJECT-17K19576, KAKENHI-INTERNATIONAL-16K21731, KAKENHI-PROJECT-24229004, KAKENHI-ORGANIZER-16H06495, KAKENHI-PUBLICLY-17H05806
[Journal Article] 細胞膜脂質成分によるT細胞シグナルソームと活性化の制御機構2017
- Author(s)
  横須賀忠、古畑昌枝、豊田博子、秦喜久美、矢那瀬紀子、町山裕亮
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 67 Pages: 321-326
- NAID
  40021132650
- Data Source
  KAKENHI-INTERNATIONAL-16K21731
[Journal Article] Role of interleukin-25 in development of spontaneous arthritis in interleukin-1 receptor antagonist-deficient mice2017
- Author(s)
  Abe Yasuharu、Nambu Aya、Yamaguchi Sachiko、Takamori Ayako、Suto Hajime、Hirose Sachiko、 Yokosuka Tadashi、Nakae Susumu、Sudo Katsuko
- Journal Title
  
  Biochemistry and Biophysics Reports
  
  Volume: 12 Pages: 62065-62065
- DOI
  10.1016/j.bbrep.2017.08.006
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-16H06501, KAKENHI-PROJECT-17H03600
[Journal Article] Blockage of Core Fucosylation Reduces Cell-Surface Expression of PD-1 and Promotes Anti-tumor Immune Responses of T Cells.2017
- Author(s)
  Okada M, Chikuma S et al.
- Journal Title
  
  Cell Reports
  
  Volume: 20 Issue: 5 Pages: 1017-1028
- DOI
  10.1016/j.celrep.2017.07.027
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08847, KAKENHI-PROJECT-17K15451, KAKENHI-INTERNATIONAL-16K21731, KAKENHI-ORGANIZER-16H06495, KAKENHI-PLANNED-16H06501, KAKENHI-PUBLICLY-17H05801, KAKENHI-PROJECT-17H03600, KAKENHI-PROJECT-17H07088, KAKENHI-PROJECT-15J07566, KAKENHI-PROJECT-15K19128
[Journal Article] Micro-adhesion rings surrounding TCR microclusters are essential for T cell activation.2016
- Author(s)
  Akiko Hashimoto-Tane, Machie Sakuma, Hiroshi Ike, Tadashi Yokosuka, Yayoi Kimura, Osamu Ohara, Takashi Saito
- Journal Title
  
  Journal of Experimental Medicine
  
  Volume: 213 Pages: 1609-1625
- DOI
  10.1007/978-3-642-03858-7_5
- ISBN
  9783642038570, 9783642038587
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-15H01194
[Journal Article] 最先端イメージング技術によるTCRシグナル研究の進歩2016
- Author(s)
  横須賀忠、古畑昌枝、豊田博子、畑喜久美、矢那瀬紀子、町山裕亮
- Journal Title
  
  臨床免疫・アレルギー
  
  Volume: 66 Pages: 169-176
- NAID
  40020941348
- Data Source
  KAKENHI-PUBLICLY-15H01194
[Journal Article] Micro-adhesion rings surrounding TCR microclusters are essential for T cell activation2016
- Author(s)
  Hashimoto-Tane A, Sakuma M, Ike H, Yokosuka T, Kimura Y, Ohara O, Saito T.
- Journal Title
  
  J. Exp. Med.
  
  Volume: 213 Issue: 8 Pages: 1609-1625
- DOI
  10.1084/jem.20151088
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-16H06495, KAKENHI-PLANNED-16H06501, KAKENHI-PROJECT-16K08851, KAKENHI-INTERNATIONAL-16K21731, KAKENHI-PROJECT-16H05230
[Journal Article] 最先端イメージング技術によるTCRシグナル研究の進歩2016
- Author(s)
  横須賀忠、古畑昌枝、豊田博子、秦喜久美、矢那瀬紀子、町山裕亮
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 66 Pages: 169-176
- NAID
  40020941348
- Data Source
  KAKENHI-INTERNATIONAL-16K21731
[Journal Article] The Multifaceted Role of PD-1 in Health and Disease2016
- Author(s)
  Badr MEISG, Hata K, Furuhata M, Toyoda H, Yokosuka T.
- Journal Title
  
  Choronic Inflammation
  
  Volume: 1 Pages: 441-457
- DOI
  10.1007/978-4-431-56068-5_34
- ISBN
  9784431560661, 9784431560685
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-ORGANIZER-16H06495, KAKENHI-PLANNED-16H06501, KAKENHI-PROJECT-16K08746, KAKENHI-INTERNATIONAL-16K21731
[Journal Article] Differential Regulation of T-dependent and -independent Antibody Responses through Arginine Methyltransferase PRMT1 in vivo2016
- Author(s)
  Kikumi Hata, Noriko Yanase, Katsuko Sudo, Hiroshi Kiyonari, Yoshiko Mukumoto, Junichiro Mizuguchi, Tadashi Yokosuka
- Journal Title
  
  FEBS Letters
  
  Volume: 590 Issue: 8 Pages: 1200-1210
- DOI
  10.1002/1873-3468.12161
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01194, KAKENHI-PROJECT-24590286, KAKENHI-PROJECT-24590590
[Journal Article] 最先端イメージング技術によるTCRシグナル研究の進歩2016
- Author(s)
  横須賀忠、古畑昌枝、豊田博子、秦喜久美、矢那瀬紀子、町山裕亮
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 66 Pages: 169-176
- NAID
  40020941348
- Data Source
  KAKENHI-ORGANIZER-16H06495
[Journal Article] T細胞免疫シナプス研究の最新事情2015
- Author(s)
  横須賀忠
- Journal Title
  
  臨床免疫・アレルギー
  
  Volume: 63 Pages: 193-200
- NAID
  40020362893
- Data Source
  KAKENHI-PUBLICLY-25113725
[Journal Article] 免疫シナプス2015
- Author(s)
  横須賀忠
- Journal Title
  
  生体の科学
  
  Volume: 66 Pages: 522-523
- Data Source
  KAKENHI-PUBLICLY-15H01194
[Journal Article] 免疫シナプス2015
- Author(s)
  横須賀忠
- Journal Title
  
  生体の科学
  
  Volume: 66 Pages: 522-523
- Data Source
  KAKENHI-PROJECT-24590590
[Journal Article] T細胞免疫シナプス研究の最新事情2015
- Author(s)
  横須賀忠
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 63 Pages: 193-200
- NAID
  40020362893
- Data Source
  KAKENHI-PUBLICLY-15H01194
[Journal Article] T細胞活性化におけるチェックポイント2015
- Author(s)
  横須賀忠
- Journal Title
  
  炎症と免疫
  
  Volume: 23 Pages: 10-20
- Data Source
  KAKENHI-PUBLICLY-15H01194
[Journal Article] T細胞免疫シナプス研究の最新事情2015
- Author(s)
  横須賀忠
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 63 Pages: 193-200
- NAID
  40020362893
- Data Source
  KAKENHI-PROJECT-24590590
[Journal Article] Clustering of CARMA1 through SH3-GUK domain interactions is required for its activation of NF-kB signaling2015
- Author(s)
  Hara, H., Yokosuka, T., Hirakawa, H., Ishihara, C., Yasukawa, S., Yamazaki, M., Koseki, H., Yoshida, H. and Saito, T.
- Journal Title
  
  Nat. Commun.
  
  Volume: 6 Issue: 1 Pages: 5555-5555
- DOI
  10.1038/ncomms6555
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24229004, KAKENHI-PROJECT-24390256, KAKENHI-PROJECT-24590590, KAKENHI-PUBLICLY-25113725, KAKENHI-PROJECT-25460594
[Journal Article] T細胞におけるPD-1の生理機能と分子基盤2014
- Author(s)
  横須賀忠
- Journal Title
  
  腫瘍内科
  
  Volume: 14 Pages: 419-426
- Data Source
  KAKENHI-PUBLICLY-25113725
[Journal Article] T細胞活性化におけるチェックポイント2014
- Author(s)
  横須賀忠
- Journal Title
  
  炎症と免疫
  
  Volume: 23 Pages: 10-20
- Data Source
  KAKENHI-PUBLICLY-25113725
[Journal Article] T細胞におけるPD-1の生理機能と分子基盤2014
- Author(s)
  横須賀忠
- Journal Title
  
  腫瘍内科
  
  Volume: 14 Pages: 419-426
- Data Source
  KAKENHI-PROJECT-24590590
[Journal Article] T細胞活性化におけるチェックポイント2014
- Author(s)
  横須賀忠
- Journal Title
  
  炎症と免疫
  
  Volume: 23 Pages: 10-20
- Data Source
  KAKENHI-PROJECT-24590590
[Journal Article] リンパ球に特異的なアクチン脱キャッピングタンパク質RltprはCD28を介するT細胞の活性化と制御性T細胞の分化に必須である2013
- Author(s)
  横須賀忠、斉藤隆、Bernard Malissen
- Journal Title
  
  ライフサイエンス新着論文レビュー
  
  Volume: -
- Data Source
  KAKENHI-PUBLICLY-25113725
[Journal Article] The lymphoid lineage-specific actin-uncapping protein Rltpr is essential for costimulation via CD28 and the development of regulatory T cells2013
- Author(s)
  Liang, Y., Cucchetti, M., Roncagalli, R., Yokosuka, T., Malzac, A., Bertosio, E., Imbert, J., Nijman, I.J., Suchanek, M., Saito, T., Wulfing, C., Malissen, B., Malissen, M.
- Journal Title
  
  Nat. Immunol.
  
  Volume: 14 Issue: 8 Pages: 858-866
- DOI
  10.1038/ni.2634
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24229004, KAKENHI-PROJECT-24590590, KAKENHI-PUBLICLY-25113725
[Journal Article] リンパ球に特異的なアクチン脱キャッピングタンパク質RltprはCD28を介するT細胞の活性化と制御性T細胞の分化に必須である2013
- Author(s)
  横須賀忠、斉藤隆、Bernard Malissen
- Journal Title
  
  ライフサイエンス新着論文レビュー
  
  Volume: -
- Data Source
  KAKENHI-PROJECT-24590590
[Journal Article] Programmed cell death-1 forms negative costimulatorymicroclusters that directly inhibit T cell receptor signaling by recruiting phosphatase SHP22012
- Author(s)
  Yokosuka T, Takamatsu M, Kobayashi-Imanishi W, Hashimoto-Tani A, Azuma M, Saito T
- Journal Title
  
  J Exp Med
  
  Volume: 209 Issue: 6 Pages: 935-945
- DOI
  10.1084/jem.20112741
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249082, KAKENHI-PROJECT-24229004, KAKENHI-PROJECT-24590590, KAKENHI-PROJECT-24590591, KAKENHI-PUBLICLY-23113521
[Journal Article] CIN85 regulates the canonical NF-κB pathway and subsequent B cell responses2011
- Author(s)
  Kometani K, Yamada T, Sasaki Y, Yokosuka T, Saito T, Rajewsky K, Ishiai M, Hikida M, Kurosaki T.
- Journal Title
  
  J Exp Med
  
  Volume: 208(7) Pages: 1447-1457
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590548
[Journal Article] Dynein-driven transport of T cell receptor microclusters regulates immune synapse formation and T cell activation2011
- Author(s)
  Hashimoto-Tane A, Yokosuka T, Sakata-Sogawa K, Sakuma M, Ishihara C, Tokunaga M, Saito T.
- Journal Title
  
  Immunity
  
  Volume: 34(6) Pages: 919-931
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590548
[Journal Article] Dynein-driven transport of T cell receptor microclusters regulates immune synapse formation and T cell activation2011
- Author(s)
  Hashimoto-Tane A, Yokosuka T, Sakata-Sogawa K, Sakuma M, Ishihara C, Tokunaga M, Saito T.
- Journal Title
  
  Immunity
  
  Volume: 34 Pages: 919-931
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109005
[Journal Article] A motif in the V3 domain of the kinase PKC-θ determines its localization in the immunological synapse and functions in T cells via association with CD282011
- Author(s)
  Kong, K-F., Yokosuka, T., Canonigo-Balancio, A.J., et al
- Journal Title
  
  Nat.Immunol.
  
  Volume: 12 Issue: 11 Pages: 1105-1112
- DOI
  10.1038/ni.2120
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19059013, KAKENHI-PROJECT-19109005, KAKENHI-PROJECT-21590548, KAKENHI-PUBLICLY-23113521, KAKENHI-PROJECT-24590590, KAKENHI-PUBLICLY-25113725
[Journal Article] A motif in the V3 domain of the kinase PKC-θdetermines its localization in the immunological synapse and functions in T cells via association with CD282011
- Author(s)
  Kong K-F, Yokosuka T, Canonigo-Balancio A. J, Isakov N, Saito T, Altman A.
- Journal Title
  
  Nat. Immunol
  
  Volume: 12(11) Pages: 1105-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590548
[Journal Article] CIN85 regulates the canonical NF-κB pathway and subsequent B cell responses2011
- Author(s)
  Kometani K, Yamada T, Sasaki Y, Yokosuka T, Saito T, Rajewsky K, Ishiai M, Hikida M, Kurosaki T.
- Journal Title
  
  J. Exp. Med
  
  Volume: 208 Pages: 1447-1457
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109005
[Journal Article] Spatiotemporal basis of CTLA-4 costimulatory molecule-mediated negative regulation of T cell activation2010
- Author(s)
  Yokosuka T, Kobayashi W, Takamatsu M, Sakata-Sogawa K, Zeng H, Hashimoto-Tane A, Yagita H, Tokunaga M, Saito T
- Journal Title
  
  Immunity
  
  Volume: 33 Pages: 326-339
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109005
[Journal Article] Spatiotemporal basis of CTLA-4 costimulatory molecule-mediated negative regulation of T cell activation.2010
- Author(s)
  Tadashi Yokosuka
- Journal Title
  
  Immunity
  
  Volume: 33 Pages: 326-339
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109005
[Journal Article] T cell receptor-microclusters critical for T-cell activation are formed independently of lipid raft clustering2010
- Author(s)
  Hashimoto-Tane A, Yokosuka T, Ishihara C, Sakuma M, Kobayashi W and Saito T.
- Journal Title
  
  Mol. Cel. Biol
  
  Volume: 30 Pages: 3421-3429
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109005
[Journal Article] Dynamic regulation of T cell activation and co-stimulation through TCR-microclusters2010
- Author(s)
  Saito T, Yokosuka T, Hashimoto-Tane A.
- Journal Title
  
  FEBS Lett
  
  Volume: 584 Pages: 4865-4871
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109005
[Journal Article]2010
- Author(s)
  Tadashi Yokosuka
- Journal Title
  
  Immunological Synapse (Current Topics in Microbiology and Immunology)(Springer-Verlag Berlin Heidelberg)
  
  Pages: 81-107
- Data Source
  KAKENHI-PROJECT-19109005
[Journal Article]2010
- Author(s)
  Tadashi Yokosuka
- Journal Title
  
  Immunological Synapse(Current Topics in Microbiology and Immunology)(Springer-Verlag Berlin Heidelberg)
  
  Pages: 81-107
- Data Source
  KAKENHI-PROJECT-21590548
[Journal Article] Spatiotemporal basis of CTLA-4 costimulatory molecule-mediated negative regulation of T cell activation2010
- Author(s)
  Tadashi Yokosuka
- Journal Title
  
  Immunity
  
  Volume: 33 Pages: 326-339
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590548
[Journal Article] T cell receptor-microclusters critical for T-cell activation are formed independently of lipid raft clustering2010
- Author(s)
  Hashimoto-Tane A, Yokosuka T, Ishihara C, Sakuma M, Kobayashi W, Saito T.
- Journal Title
  
  Mol Cel Biol
  
  Volume: 30(14) Pages: 3421-3429
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590548
[Journal Article] Dynamic regulation of T cell activation and co-stimulation through TCR-microclusters2010
- Author(s)
  Saito T, Yokosuka T, Hashimoto-Tane A.
- Journal Title
  
  FEBS Lett
  
  Volume: 584 Pages: 4865-4871
- Data Source
  KAKENHI-PROJECT-21590548
[Journal Article] Spatiotemporal basis of CTLA-4 costimulatory molecule-mediated negative regulation of T cell activation2010
- Author(s)
  Yokosuka T, Kobayashi W, Takamatsu M, Sakata-Sogaw, K, Zen H, Hashimoto-Tane A, Yagita H, Tokunaga M, Saito T.
- Journal Title
  
  Immunity
  
  Volume: 33(3) Pages: 326-339
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590548
[Journal Article] Dynamic regulation of T-cell costimulation through TCR?CD28 microclusters2009
- Author(s)
  Yokosuka T. and Saito T.
- Journal Title
  
  Immunol. Rev. 229
  
  Pages: 27-40
- Data Source
  KAKENHI-PROJECT-19590504
[Journal Article] Dynamic regulation of T-cell costimulation through TCR-CD28 microclusters2009
- Author(s)
  Tadashi Yokosuka
- Journal Title
  
  Immnological Review 299
  
  Pages: 27-40
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590548
[Journal Article] CRTAM confers late-stage activation of CD8+T cells to regulate retention within lymph node2009
- Author(s)
  Takeuchi A, Itoh Y, Takumi A, Ishihara C, Arase N, Yokosuka T, Koseki H, Yamasaki S, Takai Y, Miyoshi J, Ogasawara K, and Saito T.
- Journal Title
  
  J. Immunol
  
  Volume: 183 Pages: 4220-4228
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109005
[Journal Article] Dynamic regulation of T-cell costimulation through TCR-CD28 microclusters2009
- Author(s)
  Tadashi Yokosuka
- Journal Title
  
  Immunological Reviews 229
  
  Pages: 27-40
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109005
[Journal Article] Dynamic regulation of T-cell costimulation through TCR-CD28 microclusters2009
- Author(s)
  Yokosuka T and Saito T
- Journal Title
  
  Immunol. Rev
  
  Volume: 229 Pages: 27-40
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109005
[Journal Article] Costimulation signals mediated by CD28-microclusters2009
- Author(s)
  Yokosuka, T., Saito, T.
- Journal Title
  
  Immunol.Rev. 229
  
  Pages: 27-40
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109005
[Journal Article] Dynamic regulation of T-cell costimulation through TCR-CD28 microclusters2009
- Author(s)
  Yokosuka T, Saito T.
- Journal Title
  
  Immunol Rev
  
  Volume: 229(1) Pages: 27-40
- Data Source
  KAKENHI-PROJECT-21590548
[Journal Article] CRTAM confers late-stage activation of CD8+T cells to regulate retention within lymph node2009
- Author(s)
  Takeuchi A, Itoh Y, Takumi A, Ishihara C, Arase N, Yokosuka T, Koseki H, Yamasaki S, Takai Y, Miyoshi J, Ogasawara K, Saito T.
- Journal Title
  
  J Immunol
  
  Volume: 183(7) Pages: 4220-4228
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590548
[Journal Article] Spatiotemporal regulation of T cell costimulation by TCR-CD28 microclusters and protein kinase C θ translocation2008
- Author(s)
  Yokosuka, T.
- Journal Title
  
  Immunity 29
  
  Pages: 589-601
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109005
[Journal Article] Spatiotemporal regulation of T cell costimulation by TCR-CD28 microclusters through protein kinase C θ translocation2008
- Author(s)
  Yokosuka T., Kobayashi, W., Sakata-Sogawa K., Hashimoto-Tane, A., Dustin, M.L., Tokunaga. M., Saito, T.
- Journal Title
  
  Immunity 29
  
  Pages: 589-301
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590504
[Journal Article] Spatiotemporal regulation of T cell costimulation by TCR-CD28 microclusters through protein kinase C θ translocation2008
- Author(s)
  Yokosuka T, Kobayashi W, Sakata-Sogawa K, Takamatsu M, Hashimoto-Tane A, Dustin ML, Tokunaga M, Saito T
- Journal Title
  
  Immunity 29
  
  Pages: 589-601
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109005
[Journal Article] T細胞活性化時のTCRとシグナル伝達分子の動態2008
- Author(s)
  横須賀忠
- Journal Title
  
  臨床免疫・アレルギー科(Clinical Immunology & Allergology) 50
  
  Pages: 247-254
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590504
[Journal Article] LFA-1 decreases the antigen dose for T cell activation in vivo2008
- Author(s)
  Wang Y, Shibuya K, Yamashita Y, Shirakawa J, Shibata K, Kai H, Yokosuka T, Saito T, Honda S, Tahara-Hanaoka S, Shibuya A.
- Journal Title
  
  Int. Immunol. 20
  
  Pages: 1119-1127
- NAID
  10022599219
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590504
[Journal Article] Spatiotemporal regulation of T cell costimulation by TCR-CD28 microclusters through protein kinase Cθtranslocation2008
- Author(s)
  Yokosuka T, Kobayashi W, Sakata-Sogawa, K, Takamatsu M, Hashimoto-Tane A, Dustin ML, Tokunaga M, Saito T.
- Journal Title
  
  Immunity
  
  Volume: 29 Pages: 589-601
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109005
[Journal Article] Genetic analysis reveals an intrinsic property of the germinal center B cells to generate A:T mutations2008
- Author(s)
  Ouchida R, Ukai A, Mori H, Kawamura K, Dolle ME, Tagawa M, Sakamoto A, Tokuhisa T, Yokosuka T, Saito T, Yokoi M, Hanaoka F, Vijg J, Wang JY.
- Journal Title
  
  DNA Repair 7
  
  Pages: 1392-1398
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590504
[Journal Article] Spatiotemporal regulation of T cell costimulation by TCR-CD28 microclusters through protein kinase C θ translocation2008
- Author(s)
  Yokosuka, T.
- Journal Title
  
  Immunity 29
  
  Pages: 589-601
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590504
[Journal Article] Cloning of B cell-specific membrane tetraspanning molecule BTS possessing B cell proliferation-inhibitory function2007
- Author(s)
  Suenaga T, Arase H, Yamasaki S, Kohno M, Yokosuka T, Takeuchi A, Hattori T, Saito T.
- Journal Title
  
  Eur. J. Immunol. 37
  
  Pages: 3197-3207
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590504
[Journal Article] 免疫シナプスを構成するTCRマイクロクラスターとT細胞活性化機構2007
- Author(s)
  横須賀忠
- Journal Title
  
  Annual Review免疫2008
  
  Pages: 1-11
- Data Source
  KAKENHI-PROJECT-19590504
[Journal Article] Cloning of B cell-specific membrane tetraspanning molecule BTS possessing B cell proliferation-inhibitory function2007
- Author(s)
  Suenaga T, Arase H, Yamasaki S, Kohno M, Yokosuka T, Takeuchi A, Hattori T, Saito T.
- Journal Title
  
  Eur. J. Immunol
  
  Volume: 37 Pages: 3197-3207
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109005
[Journal Article] T細胞活性化の開始と維持を担うシグナルソーム'TCRマイクロクラスター'2006
- Author(s)
  横須賀忠
- Journal Title
  
  実験医学 24・4
  
  Pages: 499-501
- Data Source
  KAKENHI-PROJECT-17790330
[Journal Article] T細胞受容体のクラスター形成とT細胞活性化のシグナル伝達2006
- Author(s)
  横須賀忠
- Journal Title
  
  臨床免疫・アレルギー科 46
  
  Pages: 227-232
- NAID
  40007394147
- Data Source
  KAKENHI-PROJECT-17790330
[Journal Article] Newly generated T cell receptor microclusters initiate and sustain T cell activation by recruitment of Zap70 and SLP-762005
- Author(s)
  Yokosuka, T
- Journal Title
  
  Nat.Immunol. 6・12
  
  Pages: 1253-1253
- Data Source
  KAKENHI-PROJECT-17790330
[Journal Article] フローサイトメトリー2004
- Author(s)
  横須賀忠
- Journal Title
  
  蛋白質核酸酵素 49
  
  Pages: 1620-1627
- Data Source
  KAKENHI-PROJECT-15790247
[Journal Article] CD8^+T細胞のエフェクター、メモリーへの分化と細胞増殖2004
- Author(s)
  横須賀忠
- Journal Title
  
  臨床免疫 42・3
  
  Pages: 271-277
- Data Source
  KAKENHI-PROJECT-15790247
[Journal Article] Programmed cell death 1 forms negative costimulatory microclusters that directly inhibit T cell receptor signaling by recruiting phosphatase SHP2
- Author(s)
  Yokosuka T, Takamatsu M, Kobayashi-Imanishi W, Hashimoto-Tane A, Azuma M, Saito T.
- Journal Title
  
  J. Exp. Med
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109005
[Patent] クラスターを形成し得る細胞表面レセプターを有する細胞の活性化制御剤およびそのスクリーニング方法2005
- Inventor(s)
  斉藤隆, 横須賀忠
- Industrial Property Rights Holder
  理化学研究所
- Industrial Property Number
  2005-298279
- Filing Date
  2005-10-13
- Data Source
  KAKENHI-PROJECT-17790330
[Presentation] PD-1-mediated suppression of CAR-T cells via CAR signalosomes colocalized by PD-12024
- Author(s)
  Yosuke Yoshida、Hiroaki Machiyama、Ei Wakamatsu、Arata Takeuchi、Hitoshi Nishijima、Tetsushi Nishikawa、Ryohei Matsushima、Masae Furuhata、Hiroko Toyota、Mamonkin Maksim、Brenner Malcolm K、Tadashi Yokosuka
- Organizer
  第52回日本免疫学会総会
- Data Source
  KAKENHI-PROJECT-23K27466
[Presentation] 超解像イメージングが解明する免疫チェックポイント阻害療法の分子メカニズム2024
- Author(s)
  横須賀忠、西航、松島遼平、西川哲史、吉田洋輔、竹原朋宏、西嶋仁、町山裕亮、若松英、竹内新
- Organizer
  第51回日本集中治療医学会総会
- Invited
- Data Source
  KAKENHI-PUBLICLY-23H04790
[Presentation] 超解像イメージングが解明する免疫チェックポイント阻害療法の分子メカニズム2024
- Author(s)
  横須賀忠、西航、松島遼平、西川哲史、吉田洋輔、竹原朋宏、西嶋仁、町山裕亮、若松英、竹内新
- Organizer
  第51回日本集中治療医学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-23K27466
[Presentation] CD4/CD8 coreceptor binding to MHCs positively regulate CAR-T cell response via translocation of Lck into CAR microclusters2024
- Author(s)
  Hiroaki Machiyama、Ei Wakamatsu、Arata Takeuchi、Hitoshi Nishijima、Tetsushi Nishikawa、Ryohei Matsushima、Yosuke Yoshida、Masae Furuhata、Hiroko Toyota、Mamonkin Maksim、Brenner Malcolm K、Tadashi Yokosuka
- Organizer
  第52回日本免疫学会総会
- Data Source
  KAKENHI-PROJECT-23K27466
[Presentation] c-SMAC formation in double positive T cells functions as a checkpoint in thymic selection2024
- Author(s)
  Hitoshi Nishijima、Ei Wakamatsu、Hiroaki Machiyama、Arata Takeuchi、Tetsushi Nishikawa、Yosuke Yoshida、Tadashi Yokosuka
- Organizer
  第52回日本免疫学会総会
- Data Source
  KAKENHI-PROJECT-23K27466
[Presentation] PD-1-mediated suppression of CAR-T cells via CAR signalosomes colocalized by PD-12024
- Author(s)
  Yosuke Yoshida、Hiroaki Machiyama、Ei Wakamatsu、Arata Takeuchi、Hitoshi Nishijima、Tetsushi Nishikawa、Ryohei Matsushima、Masae Furuhata、Hiroko Toyota、Mamonkin Maksim、Brenner Malcolm K、Tadashi Yokosuka
- Organizer
  第52回日本免疫学会総会
- Data Source
  KAKENHI-PUBLICLY-23H04790
[Presentation] Fine tuning of T cell activation by multistep regulation of CD6 and its ligand CD1662024
- Author(s)
  Arata Takeuchi、Tetsushi Nishikawa、Hiroaki Machiyama、Ei Wakamatsu、Hitoshi Nishijima、Masae Furuhata、Hiroko Toyota、Ryohei Matsushima、Yosuke Yoshida、Tadashi Yokosuka
- Organizer
  第52回日本免疫学会総会
- Data Source
  KAKENHI-PROJECT-23K27466
[Presentation] CD4/CD8 coreceptor binding to MHCs positively regulate CAR-T cell response via translocation of Lck into CAR microclusters2024
- Author(s)
  Hiroaki Machiyama、Ei Wakamatsu、Arata Takeuchi、Hitoshi Nishijima、Tetsushi Nishikawa、Ryohei Matsushima、Yosuke Yoshida、Masae Furuhata、Hiroko Toyota、Mamonkin Maksim、Brenner Malcolm K、Tadashi Yokosuka
- Organizer
  第52回日本免疫学会総会
- Data Source
  KAKENHI-PUBLICLY-23H04790
[Presentation] Comparison of linear and parallel co-stimulatory signaling via CD28 in the activation of Chimeric Antigen Receptor T Cells2024
- Author(s)
  Tetsushi Nishikawa、Arata Takeuchi、Hiroaki Machiyama、Ei Wakamatsu、Hitoshi Nishijima、Masae Furuhata、Hiroko Toyota、Nishi Wataru、Ryohei Matsushima、Yosuke Yoshida、Tadashi Yokosuka
- Organizer
  第52回日本免疫学会総会
- Data Source
  KAKENHI-PUBLICLY-23H04790
[Presentation] Fine tuning of T cell activation by multistep regulation of CD6 and its ligand CD1662024
- Author(s)
  Arata Takeuchi、Tetsushi Nishikawa、Hiroaki Machiyama、Ei Wakamatsu、Hitoshi Nishijima、Masae Furuhata、Hiroko Toyota、Ryohei Matsushima、Yosuke Yoshida、Tadashi Yokosuka
- Organizer
  第52回日本免疫学会総会
- Data Source
  KAKENHI-PUBLICLY-23H04790
[Presentation] c-SMAC formation in double positive T cells functions as a checkpoint in thymic selection2024
- Author(s)
  Hitoshi Nishijima、Ei Wakamatsu、Hiroaki Machiyama、Arata Takeuchi、Tetsushi Nishikawa、Yosuke Yoshida、Tadashi Yokosuka
- Organizer
  第52回日本免疫学会総会
- Data Source
  KAKENHI-PUBLICLY-23H04790
[Presentation] Comparison of linear and parallel co-stimulatory signaling via CD28 in the activation of Chimeric Antigen Receptor T Cells2024
- Author(s)
  Tetsushi Nishikawa、Arata Takeuchi、Hiroaki Machiyama、Ei Wakamatsu、Hitoshi Nishijima、Masae Furuhata、Hiroko Toyota、Nishi Wataru、Ryohei Matsushima、Yosuke Yoshida、Tadashi Yokosuka
- Organizer
  第52回日本免疫学会総会
- Data Source
  KAKENHI-PROJECT-23K27466
[Presentation] 分子イメージングシステムを用いた補助刺激受容体2B4のT細胞におけるスイッチング機構の解明とCAR-T細胞への応用2023
- Author(s)
  松島遼平、若松英、齋藤顕昇、吉田洋輔、西川哲史、西航、豊田博子、古畑昌枝、町山裕亮、西嶋仁、竹内新、鈴木実、横須賀忠
- Organizer
  第26回日本がん免疫学会総会
- Data Source
  KAKENHI-PUBLICLY-23H04790
[Presentation] 免疫チェックポイント阻害剤の効果に影響するヒトPD-1変異の解析2023
- Author(s)
  西航、若松英、町山裕亮、松島遼平、西川哲史、吉田洋輔、豊田博子、古畑昌枝、西嶋仁、竹内新、池田公英、鈴木実、横須賀忠
- Organizer
  第64回日本肺癌学会学術集会
- Data Source
  KAKENHI-PUBLICLY-23H04790
[Presentation] Super-resolution imaging elucidates the molecular mechanism of CAR-T cells and ICI immunotherapy2023
- Author(s)
  横須賀忠、若松英、西嶋仁、竹内新、松島遼平、西航、西川哲史、吉田洋輔、Maksim Mamokin、Malcolm K Brenner、町山裕亮
- Organizer
  第85回日本血液学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-23K27466
[Presentation] 分子イメージングシステムを用いた補助刺激受容体2B4のT細胞におけるスイッチング機構の解明とCAR-T細胞への応用2023
- Author(s)
  松島遼平、若松英、齋藤顕昇、吉田洋輔、西川哲史、西航、豊田博子、古畑昌枝、町山裕亮、西嶋仁、竹内新、鈴木実、横須賀忠
- Organizer
  第26回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-23K27466
[Presentation] Super-resolution imaging elucidates the molecular mechanism of CAR-T cells and ICI immunotherapy2023
- Author(s)
  横須賀忠、若松英、西嶋仁、竹内新、松島遼平、西航、西川哲史、吉田洋輔、Maksim Mamokin、Malcolm K Brenner、町山裕亮
- Organizer
  第85回日本血液学会学術集会
- Invited
- Data Source
  KAKENHI-PUBLICLY-23H04790
[Presentation] キメラ抗原受容体CAR-T細胞の初期の活性化と細胞応答におけるLckの分子動態と共受容体の関与2023
- Author(s)
  町山裕亮、若松英、西嶋仁、竹内新、横須賀忠
- Organizer
  第32回京都T細胞カンファレンス
- Data Source
  KAKENHI-PROJECT-23K27466
[Presentation] ヒトPD-1マイクロクラスターの1分子イメージングを用いた治療用抗PD-1/PD-L1抗体の機能評価の研究2023
- Author(s)
  横須賀忠、西航、若松英、町山裕亮、松島遼平、吉田洋輔、西川哲史、竹原朋宏、西嶋仁、竹内新、東みゆき、鈴木実
- Organizer
  第26回日本がん免疫学会総会
- Data Source
  KAKENHI-PUBLICLY-23H04790
[Presentation] ヒトPD-1マイクロクラスターの1分子イメージングを用いた治療用抗PD-1/PD-L1抗体の機能評価の研究2023
- Author(s)
  横須賀忠、西航、若松英、町山裕亮、松島遼平、吉田洋輔、西川哲史、竹原朋宏、西嶋仁、竹内新、東みゆき、鈴木実
- Organizer
  第26回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-23K27466
[Presentation] 免疫チェックポイント阻害剤の効果に影響するヒトPD-1変異の解析2023
- Author(s)
  西航、若松英、町山裕亮、松島遼平、西川哲史、吉田洋輔、豊田博子、古畑昌枝、西嶋仁、竹内新、池田公英、鈴木実、横須賀忠
- Organizer
  第64回日本肺癌学会学術集会
- Data Source
  KAKENHI-PROJECT-23K27466
[Presentation] Super-resolution imaging elucidates the molecular mechanism of CAR-T cells and ICI immunotherapy2023
- Author(s)
  Tadashi Yokosuka
- Organizer
  第82回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PUBLICLY-23H04790
[Presentation] キメラ抗原受容体CAR-T細胞の初期の活性化と細胞応答におけるLckの分子動態と共受容体の関与2023
- Author(s)
  町山裕亮、若松英、西嶋仁、竹内新、横須賀忠
- Organizer
  第32回京都T細胞カンファレンス
- Data Source
  KAKENHI-PUBLICLY-23H04790
[Presentation] Super-resolution imaging elucidates the molecular mechanism of CAR-T cells and ICI immunotherapy2023
- Author(s)
  Tadashi Yokosuka
- Organizer
  第82回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-23K27466
[Presentation] 超解像イメージングが解明するCAR-T細胞療法とICI療法のシグナル伝達2023
- Author(s)
  横須賀忠、若松英、西嶋仁、竹内新、町山裕亮
- Organizer
  第45回日本造血・免疫細胞療法学会総会
- Data Source
  KAKENHI-INTERNATIONAL-16K21731
[Presentation] Molecular imaging unveils realistic features of T cell activation signaling via TCRs, costimulatory and coinhibitory receptors and CARs2023
- Author(s)
  Tadashi Yokosuka
- Organizer
  第20回日本臨床腫瘍学会学術集会
- Data Source
  KAKENHI-INTERNATIONAL-16K21731
[Presentation] Binding of the CD4/CD8 coreceptor to an MHC molecule positively modulates CAR-T cell response2022
- Author(s)
  Hiroaki Machiyama, Ei Wakamatsu, Arata Takeuchi, Hitoshi Nishijima, Masae Furuhata, Hiroko Toyota, Maksim Mamonkin, Malcolm K Brenner, Tadashi Yokosuka
- Organizer
  第51回日本免疫学会総会
- Data Source
  KAKENHI-PROJECT-19K22545
[Presentation] Dynamics of the PI3K signaling pathway through the cytosolic domain of ICOS2022
- Author(s)
  Ei Wakamatsu, Hiroaki Machiyama, Hiroko Toyota, Masae Furuhata, Hitoshi Nishijima, Arata Takeuchi, Tadashi Yokosuka
- Organizer
  第51回日本免疫学会総会
- Data Source
  KAKENHI-PROJECT-19K22545
[Presentation] 分子イメージングが解明するT細胞活性化機構とがん免疫療法2022
- Author(s)
  横須賀忠
- Organizer
  Hematology Web Seminar
- Invited
- Data Source
  KAKENHI-PROJECT-20H03536
[Presentation] 超解像イメージングが解明するT細胞疲弊とICIの分子メカニズム2022
- Author(s)
  横須賀忠
- Organizer
  Lung Cancer Clinical Conference
- Invited
- Data Source
  KAKENHI-PROJECT-20H03536
[Presentation] Evaluation of therapeutic PD-1 antibodies by a newly established imaging system for human PD-1 microclusters2022
- Author(s)
  Wataru Nishi, Ei Wakamatsu, Ryohei Matsushima, Tetsushi Nishikawa, Tomohiro Takehara, Hiroaki Machiyama, Hitoshi Nishijima, Arata Takeuchi, Miyuki Azuma, Makoto Suzuki, and Tadashi Yokosuka
- Organizer
  第26回日本がん免疫学会
- Data Source
  KAKENHI-INTERNATIONAL-16K21731
[Presentation] 分子イメージングが解明するT細胞活性化機構とがん免疫療法2022
- Author(s)
  横須賀忠
- Organizer
  Hematology Web Seminar
- Invited
- Data Source
  KAKENHI-PROJECT-19K22545
[Presentation] Extrinsic and intrinsic inhibition of T cell response by co-inhibitory receptors, TIGIT and CD962022
- Author(s)
  Ann Hattori, Ei Wakamatsu, Hiroaki Machiyama, Ryuji Hashimoto, Hiroko Toyota, Masae Furuhata, Hitoshi Nishijima, Arata Takeuchi, Tadashi Yokosuka
- Organizer
  第51回日本免疫学会総会
- Data Source
  KAKENHI-INTERNATIONAL-16K21731
[Presentation] リンパ節の皮髄境界面は新規の間質細胞サブセットで構成され、リンパ球に抗原認識の場を提供する2022
- Author(s)
  竹内新、神田泰洋、小澤まどか、町山裕亮、横須賀忠、片貝智哉
- Organizer
  第31回 Kyoto T Cell Conference
- Data Source
  KAKENHI-PROJECT-19K22545
[Presentation] 超解像イメージングが拓くT細胞活性化とICIの分子メカニズム2022
- Author(s)
  横須賀忠
- Organizer
  第9回 Next Generation Seminar
- Invited
- Data Source
  KAKENHI-PROJECT-20H03536
[Presentation] 超解像イメージングが解明するCAR-T細胞療法とICI療法のシグナル伝達2022
- Author(s)
  横須賀忠、若松英、竹内新、町山裕亮
- Organizer
  第45回日本造血・免疫細胞療法学会
- Invited
- Data Source
  KAKENHI-PROJECT-19K22545
[Presentation] Binding of the CD4/CD8 coreceptor to an MHC molecule positively modulates CAR-T cell response2022
- Author(s)
  Hiroaki Machiyama, Ei Wakamatsu, Arata Takeuchi, Hitoshi Nishijima, Masae Furuhata, Hiroko Toyota, Maksim Mamonkin, Malcolm K Brenner, Tadashi Yokosuka
- Organizer
  第51回日本免疫学会総会
- Data Source
  KAKENHI-INTERNATIONAL-16K21731
[Presentation] 超解像イメージングが拓くがん免疫療法のシグナロソーム-免疫チェックポイント受容体とキメラ抗原受容体-2022
- Author(s)
  横須賀忠
- Organizer
  第19回日本免疫治療学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03536
[Presentation] CAR-T細胞活性化における共受容体CD8の役割2022
- Author(s)
  横須賀忠, 若松英, 西嶋仁, 竹内新, Mamonkin Maksim, Brenner K. Malcom, 町山裕亮
- Organizer
  第26回日本がん免疫学会
- Data Source
  KAKENHI-INTERNATIONAL-16K21731
[Presentation] Evaluation of therapeutic PD-1 antibodies by a newly established imaging system for human PD-1 microclusters2022
- Author(s)
  Wataru Nishi，Ei Wakamatsu、Ryohei Matsushima、Tetsushi Nishikawa, Tomohiro Takehara, Hiroaki Machiyama, Hitoshi Nishijima, Arata Takeuchi, Miyuki Azuma, Makoto Suzuki, and Tadashi Yokosuka
- Organizer
  第26回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-20H03536
[Presentation] リンパ節の皮髄境界面は新規の間質細胞サブセットで構成され、リンパ球に抗原認識の場を提供する2022
- Author(s)
  竹内新、神田泰洋、小澤まどか、町山裕亮、横須賀忠、片貝智哉
- Organizer
  第31回 Kyoto T Cell Conference
- Data Source
  KAKENHI-PROJECT-20H03536
[Presentation] キメラ抗原受容体CAR-T細胞の初期の活性化と細胞応答性におけるLckの分子動態とCD8-MHC相互作用の寄与2022
- Author(s)
  町山裕亮、若松英、西嶋仁、竹内新、横須賀忠、Maksim Mamonkin, Malcolm K Brenner
- Organizer
  第31回 Kyoto T Cell Conference
- Data Source
  KAKENHI-PROJECT-19K22545
[Presentation] Extrinsic and intrinsic inhibition of T cell response by co-inhibitory receptors, TIGIT and CD962022
- Author(s)
  Ann Hattori, Ei Wakamatsu, Hiroaki Machiyama, Ryuji Hashimoto, Hiroko Toyota, Masae Furuhata, Hitoshi Nishijima, Arata Takeuchi, Tadashi Yokosuka
- Organizer
  第51回日本免疫学会総会
- Data Source
  KAKENHI-PROJECT-19K22545
[Presentation] Molecular imaging unveils realistic features of T cell activation signaling via TCRs, costimulatory and coinhibitory receptors and CARs2022
- Author(s)
  Tadashi Yokosuka
- Organizer
  第20回日本臨床腫瘍学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19K22545
[Presentation] キメラ抗原受容体CAR-T細胞の初期の活性化と細胞応答性におけるLckの分子動態とCD8-MHC相互作用の寄与2022
- Author(s)
  町山裕亮、若松英、西嶋仁、竹内新、横須賀忠、Maksim Mamonkin, Malcolm K Brenner
- Organizer
  第31回 Kyoto T Cell Conference
- Data Source
  KAKENHI-PROJECT-20H03536
[Presentation] 超解像イメージングが解明するCAR-T細胞療法とICI療法のシグナル伝達2022
- Author(s)
  横須賀忠、若松英、竹内新、町山裕亮
- Organizer
  第45回日本造血・免疫細胞療法学会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03536
[Presentation] Dynamics of the PI3K signaling pathway through the cytosolic domain of ICOS2022
- Author(s)
  Ei Wakamatsu, Hiroaki Machiyama, Hiroko Toyota, Masae Furuhata, Hitoshi Nishijima, Arata Takeuchi, Tadashi Yokosuka
- Organizer
  第51回日本免疫学会総会
- Data Source
  KAKENHI-PROJECT-20H03536
[Presentation] CAR-T細胞活性化における共受容体CD8の役割2022
- Author(s)
  町山裕亮, 若松英, Mamonkin Maksim, Brenner K. Malcom, 横須賀忠
- Organizer
  第26回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-19K22545
[Presentation] CAR-T細胞活性化における共受容体CD8の役割2022
- Author(s)
  町山裕亮, 若松英, Mamonkin Maksim, Brenner K. Malcom, 横須賀忠
- Organizer
  第26回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-20H03536
[Presentation] Evaluation of therapeutic PD-1 antibodies by a newly established imaging system for human PD-1 microclusters2022
- Author(s)
  Wataru Nishi，Ei Wakamatsu、Ryohei Matsushima、Tetsushi Nishikawa, Tomohiro Takehara, Hiroaki Machiyama, Hitoshi Nishijima, Arata Takeuchi, Miyuki Azuma, Makoto Suzuki, and Tadashi Yokosuka
- Organizer
  第26回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-19K22545
[Presentation] 超解像イメージングが拓くがん免疫療法のシグナロソーム-免疫チェックポイント受容体とキメラ抗原受容体-2022
- Author(s)
  横須賀忠
- Organizer
  第19回日本免疫治療学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19K22545
[Presentation] Molecular imaging unveils realistic features of T cell activation signaling via TCRs, costimulatory and coinhibitory receptors and CARs2022
- Author(s)
  Tadashi Yokosuka
- Organizer
  第20回日本臨床腫瘍学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03536
[Presentation] 超解像イメージングが解明するT細胞疲弊とICIの分子メカニズム2022
- Author(s)
  横須賀忠
- Organizer
  Lung Cancer Clinical Conference
- Invited
- Data Source
  KAKENHI-PROJECT-19K22545
[Presentation] 超解像イメージングが拓くT細胞活性化とICIの分子メカニズム2022
- Author(s)
  横須賀忠
- Organizer
  第9回 Next Generation Seminar
- Invited
- Data Source
  KAKENHI-PROJECT-19K22545
[Presentation] Dynamics of the PI3K signaling pathway through the cytosolic domain of ICOS2022
- Author(s)
  Ei Wakamatsu, Hiroaki Machiyama, Hiroko Toyota, Masae Furuhata, Hitoshi Nishijima, Arata Takeuchi, Tadashi Yokosuka
- Organizer
  第51回日本免疫学会総会
- Data Source
  KAKENHI-INTERNATIONAL-16K21731
[Presentation] Extrinsic and intrinsic inhibition of T cell response by co-inhibitory receptors, TIGIT and CD962022
- Author(s)
  Ann Hattori, Ei Wakamatsu, Hiroaki Machiyama, Ryuji Hashimoto, Hiroko Toyota, Masae Furuhata, Hitoshi Nishijima, Arata Takeuchi, Tadashi Yokosuka
- Organizer
  第51回日本免疫学会総会
- Data Source
  KAKENHI-PROJECT-20H03536
[Presentation] Binding of the CD4/CD8 coreceptor to an MHC molecule positively modulates CAR-T cell response2022
- Author(s)
  Hiroaki Machiyama, Ei Wakamatsu, Arata Takeuchi, Hitoshi Nishijima, Masae Furuhata, Hiroko Toyota, Maksim Mamonkin, Malcolm K Brenner, Tadashi Yokosuka
- Organizer
  第51回日本免疫学会総会
- Data Source
  KAKENHI-PROJECT-20H03536
[Presentation] Human T cells illustrate TCR microclusters by triggering with bispecific antibodies, blinatumomab2021
- Author(s)
  Hitoshi Nishijima, Arata Takeuchi, Ei Wakamatsu, Wataru Nishi, Hiroaki Machiyama, Tadashi Yokosuka
- Organizer
  第50回日本免疫学会総会
- Data Source
  KAKENHI-PROJECT-20H03536
[Presentation] LAG-3発現CD4+ T細胞はMHC class IIのトロゴサイトーシスを介して間接的にCD4+ T細胞の活性化を抑制する2021
- Author(s)
  若松英、町山裕亮、豊田博子、古畑昌枝、西嶋仁、竹内新、横須賀忠
- Organizer
  第30回 Kyoto T Cell Conference
- Data Source
  KAKENHI-ORGANIZER-16H06495
[Presentation] LAG-3-mediated trogoytosis of MHC class II indirectly regulates CD4+ T cell actibation2021
- Author(s)
  Ei Wakamatsu, Hiroaki Machiyama, Hiroko Toyota, Masae Furuhata, Hitoshi Nishijima, Arata Takeuchi, Tadashi Yokosuka
- Organizer
  第50回日本免疫学会総会
- Data Source
  KAKENHI-ORGANIZER-16H06495
[Presentation] Establishment of a molecular imaging system to evaluate the T cell exhaustion releasing function of human PD-1/PD-L1 antibodies2021
- Author(s)
  Wataru Nishi，Ei Wakamatsu, Masae Furuhata, Hiroaki Machiyama, Hiroaki Machiyama, Hitoshi Nishijima, Arata Takeuchi, Miyuki Azuma, Tadashi Yokosuka
- Organizer
  第50回日本免疫学会総会
- Data Source
  KAKENHI-WRAPUP-21H00461
[Presentation] Establishment of a molecular imaging system to evaluate the T cell exhaustion releasing function of human PD-1/PD-L1 antibodies.2021
- Author(s)
  Nishi Wataru, Ei Wakamatsu, Nishiakwa Tetsuji, Takehara Tomohiro, Toyoda Hiroko, Furuhata Masae, Hiroaki Machiyama, Nishijima Hitoshi, Azuma Miyuki, Suzuki Makoto, Tadashi Yokosuka
- Organizer
  第50回日本免疫学会総会
- Data Source
  KAKENHI-PROJECT-20H03536
[Presentation] CAR-T細胞の抗原認識と活性化を担うCARマイクロクラスターの分子イメージング解析2021
- Author(s)
  横須賀忠、若松英、西嶋仁、竹内新、竹原朋宏、西航、西川哲史、Maksim Mamokin、Malcolm K. Brenner、町山裕亮
- Organizer
  第25回日本がん免疫学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03536
[Presentation] LAG-3-mediated trogoytosis of MHC class II indirectly regulates CD4+ T cell actibation2021
- Author(s)
  Ei Wakamatsu, Hiroaki Machiyama, Hiroko Toyota, Masae Furuhata, Hitoshi Nishijima, Arata Takeuchi, Tadashi Yokosuka
- Organizer
  第50回日本免疫学会総会
- Data Source
  KAKENHI-INTERNATIONAL-16K21731
[Presentation] The kinase Lck activate CAR-T cells independently upon co-receptor association.2021
- Author(s)
  Hiroaki Machiyama, Ei Wakamatsu, Masae Furuhata, Hiroko Toyota, Mamonkin Maksim, Brenner Malcolm K, Tadashi Yokosuka
- Organizer
  第50回日本免疫学会総会
- Data Source
  KAKENHI-PROJECT-19K22545
[Presentation] LAG-3発現CD4+ T細胞はMHC class IIのトロゴサイトーシスを介して間接的にCD4+ T細胞の活性化を抑制する2021
- Author(s)
  若松英、町山裕亮、豊田博子、古畑昌枝、西嶋仁、竹内新、横須賀忠
- Organizer
  第30回 Kyoto T Cell Conference
- Data Source
  KAKENHI-PROJECT-19K22545
[Presentation] The kinase Lck activate CAR-T cells independently upon co-receptor association2021
- Author(s)
  Hiroaki Machiyama, Ei Wakamatsu, Masae Furuhata, Hiroko Toyota, Mamonkin Maksim, Brenner K. Malcom, Tadashi Yokosuka
- Organizer
  第50回日本免疫学会総会
- Data Source
  KAKENHI-WRAPUP-21H00461
[Presentation] Establishment of a molecular imaging system to evaluate the T cell exhaustion releasing function of human PD-1/PD-L1 antibodies2021
- Author(s)
  Wataru Nishi，Ei Wakamatsu, Masae Furuhata, Hiroaki Machiyama, Hitoshi Nishijima, Arata Takeuchi, Miyuki Azuma, Tadashi Yokosuka
- Organizer
  第50回日本免疫学会総会
- Data Source
  KAKENHI-INTERNATIONAL-16K21731
[Presentation] Human T cells illustrate TCR microclusters by triggering with bispecific antibodies, blinatumomab2021
- Author(s)
  Hitoshi Nishijima, Arata Takeuchi, Ei Wakamatsu, Wataru Nishi, Hiroaki Machiyama, Tadashi Yokosuka
- Organizer
  第50回日本免疫学会総会
- Data Source
  KAKENHI-PROJECT-19K22545
[Presentation] 分子イメージングによるT細胞活性化機構の解明とがん免疫2021
- Author(s)
  横須賀忠、若松英、西嶋仁、竹内新、竹原朋宏、西航、西川哲史、Maksim Mamokin、Malcolm K. Brenner、町山裕亮
- Organizer
  第61回日本リンパ網内系学会総会
- Invited
- Data Source
  KAKENHI-WRAPUP-21H00461
[Presentation] The kinase Lck activate CAR-T cells independently upon co-receptor association2021
- Author(s)
  Hiroaki Machiyama, Ei Wakamatsu, Masae Furuhata, Hiroko Toyota, Mamonkin Maksim, Brenner K. Malcom, Tadashi Yokosuka
- Organizer
  第50回日本免疫学会総会
- Data Source
  KAKENHI-ORGANIZER-16H06495
[Presentation] 分子イメージングによるT細胞活性化機構の解明とがん免疫2021
- Author(s)
  横須賀忠、若松英、西嶋仁、竹内新、竹原朋宏、西航、西川哲史、Maksim Mamokin、Malcolm K. Brenner、町山裕亮
- Organizer
  第61回日本リンパ網内系学会総会
- Invited
- Data Source
  KAKENHI-INTERNATIONAL-16K21731
[Presentation] Human T cells illustrate TCR microclusters by triggering with bispecific antibodies, blinatumomab2021
- Author(s)
  Hitoshi Nishijima, Arata Takeuchi, Ei Wakamatsu, Wataru Nishi, Hiroaki Machiyama, Tadashi Yokosuka
- Organizer
  第50回日本免疫学会総会
- Data Source
  KAKENHI-INTERNATIONAL-16K21731
[Presentation] LAG-3-mediated trogocytosis of MHC class II indirectly regulates CD4+ T cell activation2021
- Author(s)
  Ei Wakamatsu, Hiroaki Machiyama, Hiroko Toyota, Masae Furuhata, Hitoshi Nishijima, Arata Takeuchi, Tadashi Yokosuka
- Organizer
  第50回日本免疫学会総会
- Data Source
  KAKENHI-PROJECT-19K22545
[Presentation] 分子イメージングによるT細胞活性化機構の解明とがん免疫2021
- Author(s)
  横須賀忠、若松英、西嶋仁、竹内新、竹原朋宏、西航、西川哲史、Maksim Mamokin、Malcolm K. Brenner、町山裕亮
- Organizer
  第61回日本リンパ網内系学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03536
[Presentation] LAG-3発現CD4+ T細胞はMHC class IIのトロゴサイトーシスを介して間接的にCD4+ T細胞の活性化を抑制する2021
- Author(s)
  若松英、町山裕亮、豊田博子、古畑昌枝、西嶋仁、竹内新、横須賀忠
- Organizer
  第30回 Kyoto T Cell Conference
- Data Source
  KAKENHI-PROJECT-20H03536
[Presentation] LAG-3-mediated trogoytosis of MHC class II indirectly regulates CD4+ T cell actibation2021
- Author(s)
  Ei Wakamatsu, Hiroaki Machiyama, Hiroko Toyota, Masae Furuhata, Hitoshi Nishijima, Arata Takeuchi, Tadashi Yokosuka
- Organizer
  第50回日本免疫学会総会
- Data Source
  KAKENHI-WRAPUP-21H00461
[Presentation] 分子イメージングによるT細胞活性化機構の解明とがん免疫2021
- Author(s)
  横須賀忠、若松英、西嶋仁、竹内新、竹原朋宏、西航、西川哲史、Maksim Mamokin、Malcolm K Brenner、町山裕亮
- Organizer
  第61回日本リンパ網内系学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-19K22545
[Presentation] LAG-3発現CD4+ T細胞はMHC class IIのトロゴサイトーシスを介して間接的にCD4+ T細胞の活性化を抑制する2021
- Author(s)
  若松英、町山裕亮、豊田博子、古畑昌枝、西嶋仁、竹内新、横須賀忠
- Organizer
  第30回 Kyoto T Cell Conference
- Data Source
  KAKENHI-WRAPUP-21H00461
[Presentation] CAR-T細胞の抗原認識と活性化を担うCARマイクロクラスターの分子イメージング解析2021
- Author(s)
  横須賀忠
- Organizer
  第25回日本がん免疫学会総会シンポジウム
- Data Source
  KAKENHI-ORGANIZER-16H06495
[Presentation] The kinase Lck activate CAR-T cells independently upon co-receptor association.2021
- Author(s)
  Hiroaki Machiyama, Ei Wakamatsu, Masae Furuhata, Hiroko Toyota, Mamonkin Maksim, Brenner Malcolm K, Tadashi Yokosuka
- Organizer
  第50回日本免疫学会総会
- Data Source
  KAKENHI-PROJECT-20H03536
[Presentation] LAG-3発現CD4+ T細胞はMHC class IIのトロゴサイトーシスを介して間接的にCD4+ T細胞の活性化を抑制する2021
- Author(s)
  若松英、町山裕亮、豊田博子、古畑昌枝、西嶋仁、竹内新、横須賀忠
- Organizer
  第30回 Kyoto T Cell Conference
- Data Source
  KAKENHI-INTERNATIONAL-16K21731
[Presentation] Establishment of a molecular imaging system to evaluate the T cell exhaustion releasing function of human PD-1/PD-L1 antibodies2021
- Author(s)
  Wataru Nishi，Ei Wakamatsu, Masae Furuhata, Hiroaki Machiyama, Hiroaki Machiyama, Hitoshi Nishijima, Arata Takeuchi, Miyuki Azuma, Tadashi Yokosuka
- Organizer
  第50回日本免疫学会総会
- Data Source
  KAKENHI-ORGANIZER-16H06495
[Presentation] LAG-3-mediated trogocytosis of MHC class II indirectly regulates CD4+ T cell activation2021
- Author(s)
  Ei Wakamatsu, Hiroaki Machiyama, Hiroko Toyota, Masae Furuhata, Hitoshi Nishijima, Arata Takeuchi, Tadashi Yokosuka
- Organizer
  第50回日本免疫学会総会
- Data Source
  KAKENHI-PROJECT-20H03536
[Presentation] CAR-T細胞の抗原認識と活性化を担うCARマイクロクラスターの分子イメージング解析2021
- Author(s)
  横須賀忠、若松英、西嶋仁、竹内新、竹原朋宏、西航、西川哲史、Maksim Mamokin、Malcolm K Brenner、町山裕亮
- Organizer
  第25回日本がん免疫学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-19K22545
[Presentation] Human T cells illustrate TCR microclusters by triggering with bispecific antibodies, blinatumomab2021
- Author(s)
  Hitoshi Nishijima, Arata Takeuchi, Ei Wakamatsu, Wataru Nishi, Hiroaki Machiyama, Tadashi Yokosuka
- Organizer
  第50回日本免疫学会総会
- Data Source
  KAKENHI-WRAPUP-21H00461
[Presentation] Establishment of a molecular imaging system to evaluate the T cell exhaustion releasing function of human PD-1/PD-L1 antibodies.2021
- Author(s)
  Nishi Wataru, Ei Wakamatsu, Nishiakwa Tetsuji, Takehara Tomohiro, Toyoda Hiroko, Furuhata Masae, Hiroaki Machiyama, Nishijima Hitoshi, Azuma Miyuki, Suzuki Makoto, Tadashi Yokosuka
- Organizer
  第50回日本免疫学会総会
- Data Source
  KAKENHI-PROJECT-19K22545
[Presentation] CAR-T細胞の抗原認識と活性化を担うCARマイクロクラスターの分子イメージング解析2021
- Author(s)
  横須賀忠
- Organizer
  第25回日本がん免疫学会総会シンポジウム
- Invited
- Data Source
  KAKENHI-WRAPUP-21H00461
[Presentation] 分子イメージングによるT細胞活性化機構の解明とがん免疫2021
- Author(s)
  横須賀忠、若松英、西嶋仁、竹内新、竹原朋宏、西航、西川哲史、Maksim Mamokin、Malcolm K. Brenner、町山裕亮
- Organizer
  第61回日本リンパ網内系学会総会
- Invited
- Data Source
  KAKENHI-ORGANIZER-16H06495
[Presentation] Human T cells illustrate TCR microclusters by triggering with bispecific antibodies, blinatumomab2021
- Author(s)
  Hitoshi Nishijima, Arata Takeuchi, Ei Wakamatsu, Wataru Nishi, Hiroaki Machiyama, Tadashi Yokosuka
- Organizer
  第50回日本免疫学会総会
- Data Source
  KAKENHI-ORGANIZER-16H06495
[Presentation] CAR-T細胞の抗原認識と活性化を担うCARマイクロクラスターの分子イメージング解析2021
- Author(s)
  横須賀忠
- Organizer
  第25回日本がん免疫学会総会シンポジウム
- Invited
- Data Source
  KAKENHI-INTERNATIONAL-16K21731
[Presentation] The kinase Lck activate CAR-T cells independently upon co-receptor association2021
- Author(s)
  Hiroaki Machiyama, Ei Wakamatsu, Masae Furuhata, Hiroko Toyota, Mamonkin Maksim, Brenner K. Malcom, Tadashi Yokosuka
- Organizer
  第50回日本免疫学会総会
- Data Source
  KAKENHI-INTERNATIONAL-16K21731
[Presentation] 一分子動態解析法を用いたT細胞活性化におけるシグナルソームの時空間的制御機構の解明～簡単・簡便なキメラ抗原受容体CAR-T細胞療法に向けて～2020
- Author(s)
  町山裕亮、若松英、矢那瀬紀子、横須賀忠
- Organizer
  第36回日本DDS学会学術集会
- Data Source
  KAKENHI-INTERNATIONAL-16K21731
[Presentation] Role of cytoskeleton in Chimeric antigen receptor (CAR)-T cell therapy.2020
- Author(s)
  Machiyama H, Wakamatsu E, Yokosuka T
- Organizer
  The 43rd Annual Meeting of Molecular Biology Society of Japan
- Invited
- Data Source
  KAKENHI-PROJECT-19K22545
[Presentation] 一分子動態解析法を用いたT細胞活性化におけるシグナルソームの時空間的制御機構の解明～簡単・簡便なキメラ抗原受容体CAR-T細胞療法に向けて～2020
- Author(s)
  町山裕亮, 若松英, 矢那瀬紀子, 横須賀忠
- Organizer
  第36回日本DDS学会学術集会
- Invited
- Data Source
  KAKENHI-PLANNED-16H06501
[Presentation] Visualizing of neo-self phenomena in chimeric antigen receptor (CAR)-T cells.2020
- Author(s)
  町山裕亮, 若松英, 秦喜久美, 矢那瀬紀子, 竹原朋宏, 西航, Mamonkin Maksim, Brenner Malcolm K, 横須賀忠
- Organizer
  第58回日本生物物理学会年会
- Data Source
  KAKENHI-INTERNATIONAL-16K21731
[Presentation] Visualizing of neo-self phenomena in chimeric antigen receptor (CAR)-T cells.2020
- Author(s)
  町山裕亮, 若松英, 秦喜久美, 矢那瀬紀子, 竹原朋宏, 西航, Mamonkin M, Brenner MK, 横須賀忠
- Organizer
  第58回日本生物物理学会年会
- Invited
- Data Source
  KAKENHI-PLANNED-16H06501
[Presentation] Role of cytoskeleton in Chimeric antigen receptor (CAR)-T cell therapy2020
- Author(s)
  Hiroaki Machiyama, Ei Wakamatsu, Tadashi Yokosuka
- Organizer
  The 43rd Annual Meeting of Molecular Biology Society of Japan
- Data Source
  KAKENHI-INTERNATIONAL-16K21731
[Presentation] 一分子動態解析法を用いたT細胞活性化におけるシグナルソームの時空間的制御機構の解明～簡単・簡便なキメラ抗原受容体CAR-T細胞療法に向けて～2020
- Author(s)
  町山裕亮, 若松英, 矢那瀬紀子, 横須賀忠
- Organizer
  第36回日本DDS学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03536
[Presentation] Visualizing of neo-self phenomena in chimeric antigen receptor (CAR)-T cells.2020
- Author(s)
  町山裕亮, 若松英, 秦喜久美, 矢那瀬紀子, 竹原朋宏, 西航, Mamonkin M, Brenner MK, 横須賀忠
- Organizer
  第58回日本生物物理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03536
[Presentation] 分子イメージングによるPD-1ーPD-L2を介するT細胞抑制機構の解明2020
- Author(s)
  竹原朋宏, 若松英, 町山裕亮, 副島研造, 福永興壱, 横須賀忠
- Organizer
  第24回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-20H03536
[Presentation] 分子イメージングによるPD-1ーPD-L2を介するT細胞抑制機構の解明2020
- Author(s)
  竹原朋宏, 若松英, 町山裕亮, 副島研造, 福永興壱, 横須賀忠
- Organizer
  第24回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-19K22545
[Presentation] Visualizing of neo-self phenomena in chimeric antigen receptor (CAR)-T cells.2020
- Author(s)
  町山裕亮, 若松英, 秦喜久美, 矢那瀬紀子, 竹原朋宏, 西航, Mamonkin M, Brenner MK, 横須賀忠
- Organizer
  第58回日本生物物理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-19K22545
[Presentation] 分子イメージングによるPD-1ーPD-L2を介するT細胞抑制機構の解明2020
- Author(s)
  竹原朋宏、若松英、町山裕亮、副島研造、福永興壱、横須賀忠
- Organizer
  第24回日本がん免疫学会総会
- Data Source
  KAKENHI-INTERNATIONAL-16K21731
[Presentation] Role of cytoskeleton in Chimeric antigen receptor (CAR)-T cell therapy.2020
- Author(s)
  Machiyama H, Wakamatsu E, Yokosuka T
- Organizer
  The 43rd Annual Meeting of Molecular Biology Society of Japan
- Invited
- Data Source
  KAKENHI-PLANNED-16H06501
[Presentation] 分子イメージングによるPD-1ーPD-L2を介するT細胞抑制機構の解明2020
- Author(s)
  竹原朋宏, 若松英, 町山裕亮, 副島研造, 福永興壱, 横須賀忠
- Organizer
  第24回日本がん免疫学会総会
- Data Source
  KAKENHI-PLANNED-16H06501
[Presentation] 一分子動態解析法を用いたT細胞活性化におけるシグナルソームの時空間的制御機構の解明～簡単・簡便なキメラ抗原受容体CAR-T細胞療法に向けて～2020
- Author(s)
  町山裕亮, 若松英, 矢那瀬紀子, 横須賀忠
- Organizer
  第36回日本DDS学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19K22545
[Presentation] Role of cytoskeleton in Chimeric antigen receptor (CAR)-T cell therapy.2020
- Author(s)
  Machiyama H, Wakamatsu E, Yokosuka T
- Organizer
  The 43rd Annual Meeting of Molecular Biology Society of Japan
- Invited
- Data Source
  KAKENHI-PROJECT-20H03536
[Presentation] 分子イメージングが拓くT細胞活性化機構の解明とがん免疫療法2020
- Author(s)
  横須賀忠
- Organizer
  第82回日本血液学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19K22545
[Presentation] 分子イメージングが拓くT細胞活性化機構の解明とがん免疫療法2020
- Author(s)
  横須賀忠
- Organizer
  第82回日本血液学会学術集会
- Invited
- Data Source
  KAKENHI-PLANNED-16H06501
[Presentation] 分子イメージングが拓くT細胞活性化機構の解明とがん免疫療法2020
- Author(s)
  横須賀忠
- Organizer
  第82回日本血液学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03536
[Presentation] 分子イメージングが拓くT細胞活性化機構の解明とがん免疫療法2020
- Author(s)
  横須賀忠
- Organizer
  第82回日本血液学会学術集会
- Data Source
  KAKENHI-INTERNATIONAL-16K21731
[Presentation] CARマイクロクラスターによる腫瘍抗原の認識とCAR-T細胞活性化の時空間的制御機構2019
- Author(s)
  横須賀忠、若松英、矢那瀬紀子、秦喜久美、竹原朋宏、西航、町山裕亮
- Organizer
  第23回日本がん免疫学会総会
- Data Source
  KAKENHI-INTERNATIONAL-16K21731
[Presentation] Indirect suppression of CD4+ T cell activation by LAG3-mediated trogocytosis of MHC Class II.2019
- Author(s)
  Wakamatsu E, Machiyama H, Toyota H, Furuhata M, Hata K, Yanase N, Yokosuka T
- Organizer
  第48回日本免疫学会学術集会
- Data Source
  KAKENHI-ORGANIZER-16H06495
[Presentation] Different requirement of the coreceptors CD4 and CD8 for initiation of T cell activation.2019
- Author(s)
  Machiyama H Wakamatsu E, Hata K, Yanase N, Furuhata M, Toyota H, Yokosuka T
- Organizer
  第48回日本免疫学会総会
- Data Source
  KAKENHI-PROJECT-17H03600
[Presentation] Programmed cell death 2 forms coinhibitory microclusters that directly attenuate T cell receptor signaling by recruiting the phosphatase SHP2.2019
- Author(s)
  Takehara T, Wakamatsu E, Machiyama H, Yanase N, Toyota H, Furuhata M, Koichi F, Soejima K, Yokosuka T
- Organizer
  第48回日本免疫学会総会
- Data Source
  KAKENHI-PROJECT-19K22545
[Presentation] 分子イメージングが拓くT細胞活性化機構の解明とがん免疫療法2019
- Author(s)
  横須賀忠
- Organizer
  第81回日本血液学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-17H03600
[Presentation] Programmed cell death 2 forms coinhibitory microclusters that directly attenuate T cell receptor signaling by recruiting phosphatase SHP22019
- Author(s)
  Takehara T, Wakamatsu E, Machiyama H, Yanase N, Hata K, Toyoda H, Furuhata M, Yasuda H, Soejima K, Yokosuka T.
- Organizer
  American Association for Cancer Research
- Int'l Joint Research
- Data Source
  KAKENHI-INTERNATIONAL-16K21731
[Presentation] Programmed cell death 2 forms coinhibitory microclusters that directly attenuate T cell receptor signaling by recruiting the phosphatase SHP2.2019
- Author(s)
  Takehara T, Wakamatsu E, Machiyama H, Yanase N, Toyota H, Furuhata M, Koichi F, Soejima K, Yokosuka T
- Organizer
  第48回日本免疫学会学術集会
- Data Source
  KAKENHI-ORGANIZER-16H06495
[Presentation] CARマイクロクラスターによる腫瘍抗原の認識とCAR-T細胞活性化の時空間的制御機構2019
- Author(s)
  横須賀忠、若松英、矢那瀬紀子、秦喜久美、竹原朋宏、西航、町山裕亮
- Organizer
  第23回日本がん免疫学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-19K22545
[Presentation] 多様なT細胞シグナルソームによる腫瘍およびネオ・セルフ抗原認識の分子機構2019
- Author(s)
  横須賀忠、若松英、矢那瀬紀子、秦喜久美、竹原朋宏、西航、町山裕亮
- Organizer
  第92回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-19K22545
[Presentation] 分子イメージングが拓くT細胞活性化機構の解明とがん免疫療法 -免疫チェックポイント分子とキメラ抗原受容体のシグナルソーム-2019
- Author(s)
  横須賀忠
- Organizer
  Scientific Exchange Meeting in 北九州2019
- Invited
- Data Source
  KAKENHI-PLANNED-16H06501
[Presentation] 分子イメージングが拓くがん免疫応答とT細胞活性化メカニズムの解明2019
- Author(s)
  横須賀忠
- Organizer
  第75回日本口腔科学会学術集会
- Invited
- Data Source
  KAKENHI-ORGANIZER-16H06495
[Presentation] 末梢T細胞ではLckと共受容体CD4/CD8との協調的クラスター形成よって初期のTCRシグナルが惹起される2019
- Author(s)
  町山裕亮、若松英、秦喜久美、矢那瀬紀子、古畑昌枝、豊田博子、横須賀忠
- Organizer
  Kyot T cell Conference 第29回学術集会
- Data Source
  KAKENHI-PLANNED-16H06501
[Presentation] 分子イメージングが拓くT細胞活性化機構の解明とがん免疫療法～免疫チェックポイント分子とキメラ抗原受容体のシグナルソーム～2019
- Author(s)
  横須賀忠
- Organizer
  Scientific Exchange Meeting in 北九州2019
- Invited
- Data Source
  KAKENHI-ORGANIZER-16H06495
[Presentation] 分子イメージングが拓くT細胞活性化機構の解明とがん免疫療法への応用　-チェックポイント分子のとキメラ抗原受容体CARのシグナルソーム形成-2019
- Author(s)
  横須賀忠
- Organizer
  Urology Conference at Shinanomachi
- Invited
- Data Source
  KAKENHI-PLANNED-16H06501
[Presentation] 多様なT細胞シグナルソームによる腫瘍およびネオ・セルフ抗原認識の分子機構2019
- Author(s)
  横須賀忠、若松英、矢那瀬紀子、秦喜久美、竹原朋宏、西航、町山裕亮
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-ORGANIZER-16H06495
[Presentation] 分子イメージングが拓くT細胞活性化機構の解明とがん免疫応答ーチェックポイント分子とキメラ抗原受容体CARのシグナルソーム形成ー2019
- Author(s)
  横須賀忠
- Organizer
  Immuno-Oncology Forum in Ehime
- Invited
- Data Source
  KAKENHI-PROJECT-17H03600
[Presentation] Programmed cell death 2 forms coinhibitory microclusters that directly attenuate T cell receptor signaling by recruiting the phosphatase SHP2.2019
- Author(s)
  Takehara T, Wakamatsu E, Machiyama H, Yanase N, Toyota H, Furuhata M, Koichi F, Soejima K, Yokosuka T
- Organizer
  第48回日本免疫学会学術集会
- Data Source
  KAKENHI-INTERNATIONAL-16K21731
[Presentation] Programmed cell death 2 forms coinhibitory microclusters that directly attenuate T cell receptor signaling by recruiting phosphatase SHP22019
- Author(s)
  Takehara　T, Wakamatsu E, Machiyama H, Yanase N, Hata K, Toyoda H, Furuhata M, Yasuda H, Soejima K, Yokosuka T.
- Organizer
  American Association fro Cancer Reserach
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06501
[Presentation] Indirect suppression of CD4+ T cell activation by LAG3-mediated trogocytosis of MHC Class II.2019
- Author(s)
  Wakamatsu E, Machiyama H, Toyota H, Furuhata M, Hata K, Yanase N, Yokosuka T
- Organizer
  第48回日本免疫学会学術集会
- Data Source
  KAKENHI-INTERNATIONAL-16K21731
[Presentation] 分子イメージングが拓くT細胞活性化機構の解明とがん免疫療法への応用　-チェックポイント分子のとキメラ抗原受容体CARのシグナルソーム形成-2019
- Author(s)
  横須賀忠
- Organizer
  Urology Conference at Shinanomachi
- Invited
- Data Source
  KAKENHI-PROJECT-19K22545
[Presentation] Indirect suppression of CD4+ T cell activation by LAG3-mediated trogocytosis of MHC Class II.2019
- Author(s)
  Wakamatsu E, Machiyama H, Toyota H, Furuhata M, Hata K, Yanase N, Yokosuka T
- Organizer
  第48回日本免疫学会総会
- Data Source
  KAKENHI-PROJECT-19K22545
[Presentation] CARマイクロクラスターによる腫瘍抗原の認識とCAR-T細胞活性化の時空間的制御機構2019
- Author(s)
  横須賀忠、若松英、矢那瀬紀子、秦喜久美、竹原朋宏、西航、町山裕亮
- Organizer
  第23回日本がん免疫学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-17H03600
[Presentation] Indirect suppression of CD4+ T cell activation by LAG3-mediated trogocytosis of MHC Class II.2019
- Author(s)
  Wakamatsu E, Machiyama H, Toyota H, Furuhata M, Hata K, Yanase N, Yokosuka T
- Organizer
  第48回日本免疫学会総会
- Data Source
  KAKENHI-PROJECT-17H03600
[Presentation] 分子イメージングが拓くT細胞活性化機構の解明とがん免疫療法への応用 -チェックポイント分子のとキメラ抗原受容体CARのシグナルソーム形成-2019
- Author(s)
  横須賀忠
- Organizer
  Urology Conference at Shinanomachi
- Invited
- Data Source
  KAKENHI-PROJECT-17H03600
[Presentation] 末梢T細胞ではLckと共受容体CD4/CD8との協調的クラスター形成よって初期のTCRシグナルが惹起される2019
- Author(s)
  町山裕亮、若松英、秦喜久美、矢那瀬紀子、古畑昌枝、豊田博子、横須賀忠
- Organizer
  Kyot T cell Conference 第29回学術集会
- Data Source
  KAKENHI-PROJECT-17H03600
[Presentation] 多様なT細胞シグナルソームによる腫瘍およびネオ・セルフ抗原認識の分子機構2019
- Author(s)
  横須賀忠、若松英、矢那瀬紀子、秦喜久美、竹原朋宏、西航、町山裕亮
- Organizer
  第92回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-17H03600
[Presentation] Programmed cell death 2 forms coinhibitory microclusters that directly attenuate T cell receptor signaling by recruiting phosphatase SHP22019
- Author(s)
  Takehara　T, Wakamatsu E, Machiyama H, Yanase N, Hata K, Toyoda H, Furuhata M, Yasuda H, Soejima K, Yokosuka T.
- Organizer
  American Association fro Cancer Reserach
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22545
[Presentation] Programmed cell death 2 forms coinhibitory microclusters that directly attenuate T cell receptor signaling by recruiting the phosphatase SHP2.2019
- Author(s)
  Takehara T, Wakamatsu E, Machiyama H, Yanase N, Toyota H, Furuhata M, Koichi F, Soejima K, Yokosuka T
- Organizer
  第48回日本免疫学会総会
- Data Source
  KAKENHI-PROJECT-17H03600
[Presentation] Extrinsic and intrinsic inhibition of T cell response by co-inhibitory receptors, TIGIT and CD96.2019
- Author(s)
  Yanase N, Machiyama H, Toyota H, Furuhata M, Hata K, Takehara T, Wakamatsu E, Yokosuka T
- Organizer
  第48回日本免疫学会学術集会
- Data Source
  KAKENHI-ORGANIZER-16H06495
[Presentation] 末梢T細胞ではLckと共受容体CD4/CD8との協調的クラスター形成よって初期のTCRシグナルが惹起される2019
- Author(s)
  町山裕亮、若松英、秦喜久美、矢那瀬紀子、古畑昌枝、豊田博子、横須賀忠
- Organizer
  Kyot T cell Conference 第29回学術集会
- Data Source
  KAKENHI-PROJECT-19K22545
[Presentation] Different requirement of the coreceptors CD4 and CD8 for initiation of T cell activation.2019
- Author(s)
  Machiyama H Wakamatsu E, Hata K, Yanase N, Furuhata M, Toyota H, Yokosuka T
- Organizer
  第48回日本免疫学会学術集会
- Data Source
  KAKENHI-INTERNATIONAL-16K21731
[Presentation] 分子イメージングが拓くT細胞活性化機構の解明とがん免疫療法 -免疫チェックポイント分子とキメラ抗原受容体のシグナルソーム-2019
- Author(s)
  横須賀忠
- Organizer
  Scientific Exchange Meeting in 北九州2019
- Invited
- Data Source
  KAKENHI-PROJECT-17H03600
[Presentation] 分子イメージングが拓くT細胞活性化機構の解明とがん免疫療法2019
- Author(s)
  横須賀忠
- Organizer
  第81回日本血液学会学術集会
- Invited
- Data Source
  KAKENHI-PLANNED-16H06501
[Presentation] 分子イメージングが拓くT細胞活性化機構の解明とがん免疫療法ー免疫チェックポイント分子とキメラ抗原受容体のシグナルソーム2019
- Author(s)
  横須賀忠
- Organizer
  Scientific Exchange Meeting in 北九州2019
- Data Source
  KAKENHI-INTERNATIONAL-16K21731
[Presentation] CARマイクロクラスターによる腫瘍抗原の認識とCAR-T細胞活性化の時空間的制御機構2019
- Author(s)
  横須賀忠、若松英、矢那瀬紀子、秦喜久美、竹原朋宏、西航、町山裕亮
- Organizer
  第23回日本がん免疫学会総会
- Invited
- Data Source
  KAKENHI-ORGANIZER-16H06495
[Presentation] 分子イメージングが拓くT細胞活性化機構の解明とがん免疫応答ーチェックポイント分子とキメラ抗原受容体CARのシグナルソーム形成ー2019
- Author(s)
  横須賀忠
- Organizer
  Immuno-Oncology Forum in Ehime
- Invited
- Data Source
  KAKENHI-PLANNED-16H06501
[Presentation] Extrinsic and intrinsic inhibition of T cell response by co-inhibitory receptors, TIGIT and CD96.2019
- Author(s)
  Yanase N, Machiyama H, Toyota H, Furuhata M, Hata K, Takehara T, Wakamatsu E, Yokosuka T
- Organizer
  第48回日本免疫学会学術集会
- Data Source
  KAKENHI-INTERNATIONAL-16K21731
[Presentation] 分子イメージングが拓くT細胞活性化機構の解明とがん免疫応答ーチェックポイント分子とキメラ抗原受容体CARのシグナルソーム形成ー2019
- Author(s)
  横須賀忠
- Organizer
  Immuno-Oncology Forum in Ehime
- Invited
- Data Source
  KAKENHI-ORGANIZER-16H06495
[Presentation] Extrinsic and intrinsic inhibition of T cell response by co-inhibitory receptors, TIGIT and CD96.2019
- Author(s)
  Yanase N, Machiyama H, Toyota H, Furuhata M, Hata K, Takehara T, Wakamatsu E, Yokosuka T
- Organizer
  第48回日本免疫学会総会
- Data Source
  KAKENHI-PROJECT-17H03600
[Presentation] 分子イメージングが拓くT細胞活性化機構の解明とがん免疫療法2019
- Author(s)
  横須賀忠
- Organizer
  第81回日本血液学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19K22545
[Presentation] Programmed cell death 2 forms coinhibitory microclusters that directly attenuate T cell receptor signaling by recruiting phosphatase SHP22019
- Author(s)
  Takehara　T, Wakamatsu E, Machiyama H, Yanase N, Hata K, Toyoda H, Furuhata M, Yasuda H, Soejima K, Yokosuka T.
- Organizer
  American Association for Cancer Research
- Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-16H06495
[Presentation] Extrinsic and intrinsic inhibition of T cell response by co-inhibitory receptors, TIGIT and CD96.2019
- Author(s)
  Yanase N, Machiyama H, Toyota H, Furuhata M, Hata K, Takehara T, Wakamatsu E, Yokosuka T
- Organizer
  第48回日本免疫学会総会
- Data Source
  KAKENHI-PLANNED-16H06501
[Presentation] 分子イメージングが拓くT細胞活性化機構の解明とがん免疫応答ーチェックポイント分子とキメラ抗原受容体CARのシグナルソーム形成ー2019
- Author(s)
  横須賀忠
- Organizer
  Immuno-Oncology Forum in Ehime
- Invited
- Data Source
  KAKENHI-INTERNATIONAL-16K21731
[Presentation] 分子イメージングが拓くがん免疫応答とT細胞活性化メカニズムの解明2019
- Author(s)
  横須賀忠
- Organizer
  第75回日本口腔科学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19K22545
[Presentation] 分子イメージングが拓くT細胞活性化機構の解明とがん免疫療法　-免疫チェックポイント分子とキメラ抗原受容体のシグナルソーム-2019
- Author(s)
  横須賀忠
- Organizer
  Scientific Exchange Meeting in 北九州2019
- Invited
- Data Source
  KAKENHI-PROJECT-19K22545
[Presentation] Programmed cell death 2 forms coinhibitory microclusters that directly attenuate T cell receptor signaling by recruiting phosphatase SHP22019
- Author(s)
  Takehara T, Wakamatsu E, Machiyama H, Yanase N, Hata K, Toyoda H, Furuhata M, Yasuda H, Soejima K, Yokosuka T
- Organizer
  American Association fro Cancer Reserach
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03600
[Presentation] 分子イメージングが拓くがん免疫応答とT細胞活性化メカニズムの解明2019
- Author(s)
  横須賀忠
- Organizer
  第75回日本口腔科学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-17H03600
[Presentation] 分子イメージングが拓くがん免疫応答とT細胞活性化メカニズムの解明2019
- Author(s)
  横須賀忠
- Organizer
  第75回日本口腔科学会学術集会
- Invited
- Data Source
  KAKENHI-PLANNED-16H06501
[Presentation] Different requirement of the coreceptors CD4 and CD8 for initiation of T cell activation.2019
- Author(s)
  Machiyama H Wakamatsu E, Hata K, Yanase N, Furuhata M, Toyota H, Yokosuka T
- Organizer
  第48回日本免疫学会総会
- Data Source
  KAKENHI-PROJECT-19K22545
[Presentation] Extrinsic and intrinsic inhibition of T cell response by co-inhibitory receptors, TIGIT and CD96.2019
- Author(s)
  Yanase N, Machiyama H, Toyota H, Furuhata M, Hata K, Takehara T, Wakamatsu E, Yokosuka T
- Organizer
  第48回日本免疫学会総会
- Data Source
  KAKENHI-PROJECT-19K22545
[Presentation] 多様なT細胞シグナルソームによる腫瘍およびネオ・セルフ抗原認識の分子機構2019
- Author(s)
  横須賀忠、若松英、矢那瀬紀子、秦喜久美、竹原朋宏、西航、町山裕亮
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-INTERNATIONAL-16K21731
[Presentation] Programmed cell death 2 forms coinhibitory microclusters that directly attenuate T cell receptor signaling by recruiting the phosphatase SHP2.2019
- Author(s)
  Takehara T, Wakamatsu E, Machiyama H, Yanase N, Toyota H, Furuhata M, Koichi F, Soejima K, Yokosuka T
- Organizer
  第48回日本免疫学会総会
- Data Source
  KAKENHI-PLANNED-16H06501
[Presentation] 末梢T細胞ではLckと共受容体CD4/CD8との協調的クラスター形成よって初期のTCRシグナルが惹起される2019
- Author(s)
  町山裕亮、若松英、秦喜久美、矢那瀬紀子、古畑昌枝、豊田博子、横須賀忠
- Organizer
  Kyot T cell Conference 第29回学術集会
- Data Source
  KAKENHI-INTERNATIONAL-16K21731
[Presentation] Molecular imaging unveils a mechanism of T cell activation regulation by immune checkpoint microclusters.2019
- Author(s)
  Tadashi Yokosuka, Ei Wakamatsu, Tomohiro Takehara, Kikumi Hata, Noriko Yanase,Hiroaki Machiyama
- Organizer
  The 23rd JFCR-ISCC New Antitumor Agents under Development in the US, Europe and Japan
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03600
[Presentation] 末梢T細胞ではLckと共受容体CD4/CD8との協調的クラスター形成よって初期のTCRシグナルが惹起される2019
- Author(s)
  町山裕亮、若松英、秦喜久美、矢那瀬紀子、古畑昌枝、豊田博子、横須賀忠
- Organizer
  Kyot T cell Conference 第29回学術集会
- Data Source
  KAKENHI-ORGANIZER-16H06495
[Presentation] 多様なT細胞シグナルソームによる腫瘍およびネオ・セルフ抗原認識の分子機構2019
- Author(s)
  横須賀忠、若松英、矢那瀬紀子、秦喜久美、竹原朋宏、西航、町山裕亮
- Organizer
  第92回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PLANNED-16H06501
[Presentation] Indirect suppression of CD4+ T cell activation by LAG3-mediated trogocytosis of MHC Class II.2019
- Author(s)
  Wakamatsu E, Machiyama H, Toyota H, Furuhata M, Hata K, Yanase N, Yokosuka T
- Organizer
  第48回日本免疫学会総会
- Data Source
  KAKENHI-PLANNED-16H06501
[Presentation] 分子イメージングが拓くT細胞活性化機構の解明とがん免疫療法2019
- Author(s)
  横須賀忠
- Organizer
  第81回日本血液学会学術集会
- Invited
- Data Source
  KAKENHI-INTERNATIONAL-16K21731
[Presentation] CARマイクロクラスターによる腫瘍抗原の認識とCAR-T細胞活性化の時空間的制御機構2019
- Author(s)
  横須賀忠、若松英、矢那瀬紀子、秦喜久美、竹原朋宏、西航、町山裕亮
- Organizer
  第23回日本がん免疫学会総会
- Invited
- Data Source
  KAKENHI-PLANNED-16H06501
[Presentation] 分子イメージングが拓くT細胞活性化機構の解明とがん免疫療法2019
- Author(s)
  横須賀忠
- Organizer
  第81回日本血液学会学術集会
- Invited
- Data Source
  KAKENHI-ORGANIZER-16H06495
[Presentation] Different requirement of the coreceptors CD4 and CD8 for initiation of T cell activation.2019
- Author(s)
  Machiyama H Wakamatsu E, Hata K, Yanase N, Furuhata M, Toyota H, Yokosuka T
- Organizer
  第48回日本免疫学会総会
- Data Source
  KAKENHI-PLANNED-16H06501
[Presentation] 分子イメージングが拓くがん免疫応答とT細胞活性化メカニズムの解明2019
- Author(s)
  横須賀忠
- Organizer
  第75回日本口腔科学会学術集会
- Invited
- Data Source
  KAKENHI-INTERNATIONAL-16K21731
[Presentation] Different requirement of the coreceptors CD4 and CD8 for initiation of T cell activation.2019
- Author(s)
  Machiyama H Wakamatsu E, Hata K, Yanase N, Furuhata M, Toyota H, Yokosuka T
- Organizer
  第48回日本免疫学会学術集会
- Data Source
  KAKENHI-ORGANIZER-16H06495
[Presentation] 免疫チェックポイント療法はなぜ効くのか？分子イメージングが明らかにするT細胞活性化の時空間的制御機構2018
- Author(s)
  横須賀忠
- Organizer
  国立がんセンター東がん免疫セミナー
- Invited
- Data Source
  KAKENHI-ORGANIZER-16H06495
[Presentation] 胸腺ダブルポジティブT細胞におけるc-Cblのシグナルソーム形成と胸腺選択との相関2018
- Author(s)
  秦喜久美、町山裕亮、若松英、豊田博子、古畑昌枝、矢那瀬紀子、横須賀忠
- Organizer
  Kyot T cell Conference 第28回学術集会
- Data Source
  KAKENHI-INTERNATIONAL-16K21731
[Presentation] 免疫チェックポイント療法はなぜ効くのか？分子イメージングが明らかにするT細胞活性化の時空間的制御機構2018
- Author(s)
  横須賀忠
- Organizer
  国立がんセンター東がん免疫セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-17H03600
[Presentation] がん免疫と分子イメージング先端的研究ー免疫チェックポイント分子とキメラ抗原受容体CARの分子メカニズムー2018
- Author(s)
  横須賀忠
- Organizer
  第77回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-ORGANIZER-16H06495
[Presentation] Cooperative regulation of thymic selection by receptor endocytosis and signal strength through TCR and E3 ubiquitin ligase c-Cbl microcluster formation.2018
- Author(s)
  Kikumi Hata, Hiroaki Machiyama, Noriko Yanase, Masae Furuhata, Hiroko Toyota, Ei Wakamatsu, Tadashi Yokosuka
- Organizer
  第47回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-17H03600
[Presentation] Molecular imaging unveils a mechanism of T cell activation regulation by immune checkpoint microclusters.2018
- Author(s)
  Tadashi Yokosuka, Ei Wakamatsu, Tomohiro Takehara, Kikumi Hata, Noriko Yanase,Hiroaki Machiyama
- Organizer
  The 23rd JFCR-ISCC New Antitumor Agents under Development in the US, Europe and Japan
- Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-16H06495
[Presentation] がん免疫と分子イメージング先端的研究ー免疫チェックポイント分子とキメラ抗原受容体CARの分子メカニズムー2018
- Author(s)
  横須賀忠
- Organizer
  第77回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-INTERNATIONAL-16K21731
[Presentation] Cooperative regulation of thymic selection by receptor endocytosis and signal strength through TCR and E3 ubiquitin ligase c-Cbl microcluster formation.2018
- Author(s)
  Kikumi Hata, Hiroaki Machiyama, Noriko Yanase, Masae Furuhata, Hiroko Toyota, Ei Wakamatsu, Tadashi Yokosuka
- Organizer
  第47回日本免疫学会学術集会
- Data Source
  KAKENHI-ORGANIZER-16H06495
[Presentation] 胸腺ダブルポジティブT細胞におけるc-Cblのシグナルソーム形成と胸腺選択との相関2018
- Author(s)
  秦喜久美、町山裕亮、若松英、豊田博子、古畑昌枝、矢那瀬紀子、横須賀忠
- Organizer
  Kyoto T cell Conference 第28回学術集会
- Data Source
  KAKENHI-PROJECT-17H03600
[Presentation] Single molecule imaging unveils a distinct difference in Lck-dynamics between CD4+ and CD8+ T cells.2018
- Author(s)
  Hiroaki Machiyama, Ei Wakamatsu, Noriko Yanase, Kikumi Hata, Masae Furuhata, Hiroko Toyota, Tadashi Yokosuka
- Organizer
  第47回日本免疫学会学術集会
- Data Source
  KAKENHI-INTERNATIONAL-16K21731
[Presentation] Single molecule imaging unveils a distinct difference in Lck-dynamics between CD4+ and CD8+ T cells.2018
- Author(s)
  Hiroaki Machiyama, Ei Wakamatsu, Noriko Yanase, Kikumi Hata, Masae Furuhata, Hiroko Toyota, Tadashi Yokosuka
- Organizer
  第47回日本免疫学会学術集会
- Data Source
  KAKENHI-ORGANIZER-16H06495
[Presentation] 分子イメージングが明らかにするマイクロクラスターによるT細胞活性化制御機構ー免疫チェックポイント受容体とCARのマイクロクラスターー2018
- Author(s)
  横須賀忠
- Organizer
  第一三共株式会社細胞治療研究所講演会
- Invited
- Data Source
  KAKENHI-PLANNED-16H06501
[Presentation] チェックポイントから学ぶことー科学的思考は疫学や過去の結論から新天地を築くー2018
- Author(s)
  横須賀忠
- Organizer
  第35回日本呼吸器外科学会総会
- Invited
- Data Source
  KAKENHI-ORGANIZER-16H06495
[Presentation] 免疫チェックポイント阻害剤と癌治療の進歩ー臨床と基礎の視点からー2018
- Author(s)
  横須賀忠
- Organizer
  第22回日本がん分子標的治療学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-17H03600
[Presentation] チェックポイントから学ぶことー科学的思考は疫学や過去の結論から新天地を築くー2018
- Author(s)
  横須賀忠
- Organizer
  第35回日本呼吸器外科学会総会
- Invited
- Data Source
  KAKENHI-INTERNATIONAL-16K21731
[Presentation] Molecular imaging of the hCD19 CAR signalosomes, “CAR microclusters”.2018
- Author(s)
  Yanase Noriko, Machiyama Hiroaki, Wakamatsu Ei, Toyota Hiroko, Furuhata Masae, Hata Kikumi, Mamonkin Maksim, Brenner Malcolm K, Yokosuka Tadashi
- Organizer
  第47回日本免疫学会学術集会
- Data Source
  KAKENHI-PLANNED-16H06501
[Presentation] Dynamics of the PI3K signaling pathway induced by a T cell costimulator, ICOS.2018
- Author(s)
  Yokosuka Tadashi, Wakamatsu Ei, Yanase Noriko, Toyota Hiroko, Furuhata Masae, Hata Kikumi, Machiyama Hiroaki
- Organizer
  第47回日本免疫学会学術集会
- Data Source
  KAKENHI-PLANNED-16H06501
[Presentation] 分子イメージングが解明する免疫チェックポイント療法によるT細胞の疲弊解除とその分子メカニズム2018
- Author(s)
  横須賀忠
- Organizer
  中外製薬株式会社セミナー
- Invited
- Data Source
  KAKENHI-ORGANIZER-16H06495
[Presentation] イメージングが拓くT細胞活性化の時空間的制御機構ー免疫チェックポイントはなぜ効くのか？ー2018
- Author(s)
  横須賀忠
- Organizer
  第12回肝免疫フォーラム
- Invited
- Data Source
  KAKENHI-PLANNED-16H06501
[Presentation] チェックポイントから学ぶこと～科学的思考は疫学や過去の結論から新天地を築く～2018
- Author(s)
  横須賀忠
- Organizer
  第35回日本呼吸器外科学会総会
- Invited
- Data Source
  KAKENHI-PLANNED-16H06501
[Presentation] 分子イメージングが解明する免疫チェックポイント療法によるT細胞の疲弊解除とその分子メカニズム2018
- Author(s)
  横須賀忠
- Organizer
  中外製薬株式会社セミナー
- Invited
- Data Source
  KAKENHI-PLANNED-16H06501
[Presentation] 分子イメージングが明らかにするマイクロクラスターによるT細胞活性化制御機構ー免疫チェックポイント受容体とCARのマイクロクラスターー2018
- Author(s)
  横須賀忠
- Organizer
  第一三共株式会社細胞治療研究所講演会
- Invited
- Data Source
  KAKENHI-INTERNATIONAL-16K21731
[Presentation] 胸腺ダブルポジティブT細胞におけるc-Cblのシグナルソーム形成と胸腺選択との相関2018
- Author(s)
  秦喜久美、町山裕亮、若松英、豊田博子、古畑昌枝、矢那瀬紀子、横須賀忠
- Organizer
  Kyoto T cell Conference 第28回学術集会
- Data Source
  KAKENHI-PLANNED-16H06501
[Presentation] 分子イメージングによる免疫チェックポイント療法によるT細胞の疲弊解除とその分子メカニズムの解明2018
- Author(s)
  横須賀忠、若松英、矢那瀬紀子、竹原朋宏、秦喜久美、町山裕亮
- Organizer
  第22回日本がん免疫学会総会
- Invited
- Data Source
  KAKENHI-PLANNED-16H06501
[Presentation] Molecular imaging unveils a mechanism of T cell activation regulation by immune checkpoint microclusters.2018
- Author(s)
  Tadashi Yokosuka, Ei Wakamatsu, Tomohiro Takehara, Kikumi Hata, Noriko Yanase,Hiroaki Machiyama
- Organizer
  The 23rd JFCR-ISCC New Antitumor Agents under Development in the US, Europe and Japan
- Int'l Joint Research
- Data Source
  KAKENHI-INTERNATIONAL-16K21731
[Presentation] イメージングが拓くT細胞活性化の時空間的制御機構ー免疫チェックポイントはなぜ効くのか？ー2018
- Author(s)
  横須賀忠
- Organizer
  第12回肝免疫フォーラム
- Invited
- Data Source
  KAKENHI-PROJECT-17H03600
[Presentation] 分子イメージングが拓くT細胞活性化機構の解明とがん免疫応答ー;免疫チェックポイント分子とキメラ抗原受容体CARのシグナルソーム形成ー2018
- Author(s)
  横須賀忠
- Organizer
  三重大学院医学研究科セミナー
- Invited
- Data Source
  KAKENHI-ORGANIZER-16H06495
[Presentation] Molecular imaging unveils spatiotemporal regulation of T cell activation by immune checkpoint receptors.2018
- Author(s)
  Yokosuka T
- Organizer
  The 1st International Cancer Research Symposium of Training Plan for Oncology Professionals
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06501
[Presentation] Molecular imaging unveils spatiotemporal regulation of T cell activation by immune checkpoint receptors2018
- Author(s)
  Yokosuka T
- Organizer
  The 1st International Cancer Research Symposium of Training Plan for Oncology Professionals
- Invited
- Data Source
  KAKENHI-ORGANIZER-16H06495
[Presentation] 分子イメージングが明らかにするT細胞活性化の時空間的制御機構～免疫チェックポイント分子とCAR～2018
- Author(s)
  横須賀忠
- Organizer
  第59回日本肺癌学会学術集会
- Invited
- Data Source
  KAKENHI-PLANNED-16H06501
[Presentation] Dynamics of the PI3K signaling pathway induced by a T cell costimulator, ICOS.2018
- Author(s)
  Yokosuka Tadashi, Wakamatsu Ei, Yanase Noriko, Toyota Hiroko, Furuhata Masae, Hata Kikumi, Machiyama Hiroaki
- Organizer
  第47回日本免疫学会学術集会
- Data Source
  KAKENHI-ORGANIZER-16H06495
[Presentation] 免疫チェックポイント療法はなぜ効くのか？分子イメージングが明らかにするT細胞活性化の時空間的制御機構2018
- Author(s)
  横須賀忠
- Organizer
  国立がんセンター東がん免疫セミナー
- Invited
- Data Source
  KAKENHI-PLANNED-16H06501
[Presentation] 分子イメージングが解明する免疫チェックポイント療法によるT細胞の疲弊解除とその分子メカニズム2018
- Author(s)
  横須賀忠
- Organizer
  中外製薬株式会社セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-17H03600
[Presentation] 分子イメージングが明らかにするT細胞活性化の時空間的制御機構～免疫チェックポイント分子とCAR～2018
- Author(s)
  横須賀忠
- Organizer
  第59回日本肺癌学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-17H03600
[Presentation] 免疫チェックポイント阻害剤と癌治療の進歩ー臨床と基礎の視点からー2018
- Author(s)
  横須賀忠
- Organizer
  第22回日本がん分子標的治療学会学術集会
- Invited
- Data Source
  KAKENHI-INTERNATIONAL-16K21731
[Presentation] チェックポイントから学ぶことー科学的思考は疫学や過去の結論から新天地を築くー2018
- Author(s)
  横須賀忠
- Organizer
  第35回日本呼吸器外科学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-17H03600
[Presentation] Molecular imaging of the hCD19 CAR signalosomes, “CAR microclusters”.2018
- Author(s)
  Yanase Noriko, Machiyama Hiroaki, Wakamatsu Ei, Toyota Hiroko, Furuhata Masae, Hata Kikumi, Mamonkin Maksim, Brenner Malcolm K, Yokosuka Tadashi
- Organizer
  第47回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-17H03600
[Presentation] 分子イメージングが拓くT細胞活性化機構の解明とがん免疫応答～免疫チェックポイント分子とキメラ抗原受容体CARのシグナルソーム形成～2018
- Author(s)
  横須賀忠
- Organizer
  三重大学院医学研究科セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-17H03600
[Presentation] Dynamics of the PI3K signaling pathway induced by a T cell costimulator, ICOS.2018
- Author(s)
  Yokosuka Tadashi, Wakamatsu Ei, Yanase Noriko, Toyota Hiroko, Furuhata Masae, Hata Kikumi, Machiyama Hiroaki
- Organizer
  第47回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-17H03600
[Presentation] 分子イメージングが拓くT細胞活性化機構の解明とがん免疫応答～免疫チェックポイント分子とキメラ抗原受容体CARのシグナルソーム形成～2018
- Author(s)
  横須賀忠
- Organizer
  三重大学院医学研究科セミナー
- Invited
- Data Source
  KAKENHI-PLANNED-16H06501
[Presentation] 分子イメージングが明らかにするT細胞活性化の時空間的制御機構ー免疫チェックポイント分子とCARー2018
- Author(s)
  横須賀忠
- Organizer
  第59回日本肺癌学会学術集会
- Invited
- Data Source
  KAKENHI-ORGANIZER-16H06495
[Presentation] 分子イメージングによる免疫チェックポイント療法によるT細胞の疲弊解除とその分子メカニズムの解明2018
- Author(s)
  横須賀忠、若松英、矢那瀬紀子、竹原朋宏、秦喜久美、町山裕亮
- Organizer
  第22回日本がん免疫学会総会
- Data Source
  KAKENHI-INTERNATIONAL-16K21731
[Presentation] Single molecule imaging unveils a distinct difference in Lck-dynamics between CD4+ and CD8+ T cells.2018
- Author(s)
  Hiroaki Machiyama, Ei Wakamatsu, Noriko Yanase, Kikumi Hata, Masae Furuhata, Hiroko Toyota, Tadashi Yokosuka
- Organizer
  第47回日本免疫学会学術集会
- Data Source
  KAKENHI-PLANNED-16H06501
[Presentation] 分子イメージングが解明する免疫チェックポイント療法によるT細胞の疲弊解除とその分子メカニズム2018
- Author(s)
  横須賀忠
- Organizer
  中外製薬株式会社セミナー
- Invited
- Data Source
  KAKENHI-INTERNATIONAL-16K21731
[Presentation] 分子イメージングによる免疫チェックポイント療法によるT細胞の疲弊解除とその分子メカニズムの解明2018
- Author(s)
  横須賀忠、若松英、矢那瀬紀子、竹原朋宏、秦喜久美、町山裕亮
- Organizer
  第22回日本がん免疫学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-17H03600
[Presentation] 分子イメージングが明らかにするマイクロクラスターによるT細胞活性化制御機構ー免疫チェックポイント受容体とCARのマイクロクラスターー2018
- Author(s)
  横須賀忠
- Organizer
  第一三共株式会社細胞治療研究所講演会
- Invited
- Data Source
  KAKENHI-ORGANIZER-16H06495
[Presentation] Cooperative regulation of thymic selection by receptor endocytosis and signal strength through TCR and E3 ubiquitin ligase c-Cbl microcluster formation.2018
- Author(s)
  Kikumi Hata, Hiroaki Machiyama, Noriko Yanase, Masae Furuhata, Hiroko Toyota, Ei Wakamatsu, Tadashi Yokosuka
- Organizer
  第47回日本免疫学会学術集会
- Data Source
  KAKENHI-PLANNED-16H06501
[Presentation] Molecular imaging of the hCD19 CAR signalosomes, “CAR microclusters”.2018
- Author(s)
  Yanase Noriko, Machiyama Hiroaki, Wakamatsu Ei, Toyota Hiroko, Furuhata Masae, Hata Kikumi, Mamonkin Maksim, Brenner Malcolm K, Yokosuka Tadashi
- Organizer
  第47回日本免疫学会学術集会
- Data Source
  KAKENHI-INTERNATIONAL-16K21731
[Presentation] 分子イメージングが明らかにするマイクロクラスターによるT細胞活性化制御機構ー免疫チェックポイント受容体とCARのマイクロクラスターー2018
- Author(s)
  横須賀忠
- Organizer
  第一三共株式会社細胞治療研究所講演会
- Invited
- Data Source
  KAKENHI-PROJECT-17H03600
[Presentation] Single molecule imaging unveils a distinct difference in Lck-dynamics between CD4+ and CD8+ T cells.2018
- Author(s)
  Hiroaki Machiyama, Ei Wakamatsu, Noriko Yanase, Kikumi Hata, Masae Furuhata, Hiroko Toyota, Tadashi Yokosuka
- Organizer
  第47回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-17H03600
[Presentation] がん免疫と分子イメージング先端的研究～免疫チェックポイント分子とキメラ抗原受容体CARの分子メカニズム～2018
- Author(s)
  横須賀忠
- Organizer
  第77回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PLANNED-16H06501
[Presentation] がん免疫と分子イメージング先端的研究ー免疫チェックポイント分子とキメラ抗原受容体CARの分子メカニズムー2018
- Author(s)
  横須賀忠
- Organizer
  第77回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-17H03600
[Presentation] Molecular imaging unveils spatiotemporal regulation of T cell activation by immune checkpoint receptors.2018
- Author(s)
  Yokosuka T,
- Organizer
  The 1st International Cancer Research Symposium of Training Plan for Oncology Professionals
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-INTERNATIONAL-16K21731
[Presentation] Molecular imaging unveils spatiotemporal regulation of T cell activation by immune checkpoint receptors.2018
- Author(s)
  Yokosuka T
- Organizer
  The 1st International Cancer Research Symposium of Training Plan for Oncology Professionals
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03600
[Presentation] 分子イメージングによる免疫チェックポイント療法によるT細胞の疲弊解除とその分子メカニズムの解明2018
- Author(s)
  横須賀忠、若松英、矢那瀬紀子、竹原朋宏、秦喜久美、町山裕亮
- Organizer
  第22回日本がん免疫学会総会
- Data Source
  KAKENHI-ORGANIZER-16H06495
[Presentation] 胸腺ダブルポジティブT細胞におけるc-Cblのシグナルソーム形成と胸腺選択との相関2018
- Author(s)
  秦喜久美、町山裕亮、若松英、豊田博子、古畑昌枝、矢那瀬紀子、横須賀忠
- Organizer
  Kyot T cell Conference 第28回学術集会
- Data Source
  KAKENHI-ORGANIZER-16H06495
[Presentation] 分子イメージングが拓くT細胞活性化機構の解明とがん免疫応答ー;免疫チェックポイント分子とキメラ抗原受容体CARのシグナルソーム形成ー2018
- Author(s)
  横須賀忠
- Organizer
  三重大学院医学研究科セミナー
- Invited
- Data Source
  KAKENHI-INTERNATIONAL-16K21731
[Presentation] Dynamics of the PI3K signaling pathway induced by a T cell costimulator, ICOS.2018
- Author(s)
  Yokosuka Tadashi, Wakamatsu Ei, Yanase Noriko, Toyota Hiroko, Furuhata Masae, Hata Kikumi, Machiyama Hiroaki
- Organizer
  第47回日本免疫学会学術集会
- Data Source
  KAKENHI-INTERNATIONAL-16K21731
[Presentation] 免疫チェックポイント阻害剤と癌治療の進歩～臨床と基礎の視点から～2018
- Author(s)
  横須賀忠
- Organizer
  第22回日本がん分子標的治療学会学術集会
- Invited
- Data Source
  KAKENHI-PLANNED-16H06501
[Presentation] 免疫チェックポイント阻害剤と癌治療の進歩ー臨床と基礎の視点からー2018
- Author(s)
  横須賀忠
- Organizer
  第22回日本がん分子標的治療学会学術集会
- Invited
- Data Source
  KAKENHI-ORGANIZER-16H06495
[Presentation] Molecular imaging of the hCD19 CAR signalosomes, “CAR microclusters”.2018
- Author(s)
  Yanase Noriko, Machiyama Hiroaki, Wakamatsu Ei, Toyota Hiroko, Furuhata Masae, Hata Kikumi, Mamonkin Maksim, Brenner Malcolm K, Yokosuka Tadashi
- Organizer
  第47回日本免疫学会学術集会
- Data Source
  KAKENHI-ORGANIZER-16H06495
[Presentation] 分子イメージングが明らかにするT細胞活性化の時空間的制御機構ー免疫チェックポイント分子とCARー2018
- Author(s)
  横須賀忠
- Organizer
  第59回日本肺癌学会学術集会
- Invited
- Data Source
  KAKENHI-INTERNATIONAL-16K21731
[Presentation] Molecular imaging unveils a mechanism of T cell activation regulation by immune checkpoint microclusters.2018
- Author(s)
  Tadashi Yokosuka, Ei Wakamatsu, Tomohiro Takehara, Kikumi Hata, Noriko Yanase,Hiroaki Machiyama
- Organizer
  The 23rd JFCR-ISCC New Antitumor Agents under Development in the US, Europe and Japan
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06501
[Presentation] Cooperative regulation of thymic selection by receptor endocytosis and signal strength through TCR and E3 ubiquitin ligase c-Cbl microcluster formation.2018
- Author(s)
  Kikumi Hata, Hiroaki Machiyama, Noriko Yanase, Masae Furuhata, Hiroko Toyota, Ei Wakamatsu, Tadashi Yokosuka
- Organizer
  第47回日本免疫学会学術集会
- Data Source
  KAKENHI-INTERNATIONAL-16K21731
[Presentation] 免疫チェックポイント療法はなぜ効くのか？分子イメージングが明らかにするT細胞活性化の時空間的制御機構2018
- Author(s)
  横須賀忠
- Organizer
  国立がんセンター東がん免疫セミナー
- Invited
- Data Source
  KAKENHI-INTERNATIONAL-16K21731
[Presentation] イメージングが拓くT細胞活性化の時空間的制御機構ーT細胞シグナルソームの視点から免疫チェックポイント分子を解釈するー2017
- Author(s)
  横須賀忠
- Organizer
  Meet The Specialist 2017
- Invited
- Data Source
  KAKENHI-PROJECT-17H03600
[Presentation] イメージングが拓くT細胞活性化の時空間的制御機構－シグナルソームの視点から免疫チェックポイントを解釈する－2017
- Author(s)
  横須賀忠
- Organizer
  Expert Seminar of Immunology
- Invited
- Data Source
  KAKENHI-PROJECT-17H03600
[Presentation] イメージングが拓く免疫チェックポイント分子によるT細胞活性化の時空間的制御機構2017
- Author(s)
  横須賀忠
- Organizer
  第2回肺癌バイオカンファレンス
- Invited
- Data Source
  KAKENHI-PROJECT-17H03600
[Presentation] イメージンブが拓くT細胞活性化の時空間的制御機構2017
- Author(s)
  横須賀忠
- Organizer
  Expert Seminar of Immunology
- Invited
- Data Source
  KAKENHI-ORGANIZER-16H06495
[Presentation] Microclusters as a signaling unit for T cell receptor endocytosis2017
- Author(s)
  Machiyama H, Hata K, Yanase N, Hashimoto-Tane A, Saito T, Yokosuka T.
- Organizer
  The 7th International Symposium of Kyoto T Cell Conference
- Place of Presentation
  京都大学（京都・京都市）
- Year and Date
  2017-03-13
- Data Source
  KAKENHI-INTERNATIONAL-16K21731
[Presentation] Microclusters as a signaling unit for T cell receptor endocytosis2017
- Author(s)
  Machiyama H, Hata K, Yanase N, Hashimoto-Tane A, Saito T, Yokosuka T.
- Organizer
  The 7th International Symposium of Kyoto T Cell Conference
- Place of Presentation
  京都大学（京都府・京都市）
- Year and Date
  2017-03-13
- Data Source
  KAKENHI-ORGANIZER-16H06495
[Presentation] Microclusters as a functional unit for endocytosis of TCRs2017
- Author(s)
  Yokosuka T, Machiyama H, Hata K, Yanase N, Hashimoto-Tane A, Siato T
- Organizer
  第46回日本免疫学会総会学術集会
- Data Source
  KAKENHI-PLANNED-16H06501
[Presentation] イメージングが拓く免疫チェックポイント分子によるT細胞活性化の時空間的制御機構2017
- Author(s)
  横須賀忠
- Organizer
  第14回日本免疫治療学研究会学術集会
- Place of Presentation
  東京大学（東京都）
- Year and Date
  2017-02-11
- Invited
- Data Source
  KAKENHI-PLANNED-16H06501
[Presentation] イメージングが拓く免疫チェックポイント分子によるT細胞活性化の時空間的制御機構2017
- Author(s)
  横須賀忠
- Organizer
  第2回肺癌バイオカンファレンス
- Invited
- Data Source
  KAKENHI-PLANNED-16H06501
[Presentation] Microclusters as a functional unit for endocytosis of TCRs2017
- Author(s)
  Yokosuka T, Machiyama H, Hata K, Yanase N, Hashimoto-Tane A, Siato T
- Organizer
  第46回日本免疫学会総会学術集会
- Data Source
  KAKENHI-PROJECT-17H03600
[Presentation] イメージングが拓く免疫チェックポイント分子による細胞活性化の時空間的制御機構2017
- Author(s)
  横須賀忠
- Organizer
  第32回日本肺癌学会ワークショップ
- Invited
- Data Source
  KAKENHI-PLANNED-16H06501
[Presentation] イメージングが拓く免疫チェックポイント分子によるT細胞活性化の時空間的制御機構2017
- Author(s)
  横須賀忠
- Organizer
  第14回日本免疫治療学研究会学術集会
- Place of Presentation
  東京大学（東京・文京区）
- Year and Date
  2017-02-11
- Data Source
  KAKENHI-INTERNATIONAL-16K21731
[Presentation] 分子イメージングが明らかにするT細胞の活性化制御機構－がんの免疫チェックポイント療法はなぜ効くのか？－2017
- Author(s)
  横須賀忠
- Organizer
  第71回東邦医学会総会
- Invited
- Data Source
  KAKENHI-PLANNED-16H06501
[Presentation] 分子イメージングが明らかにするT細胞の活性化制御機構－がんの免疫チェックポイント療法はなぜ効くのか？－2017
- Author(s)
  横須賀忠
- Organizer
  第71回東邦医学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-17H03600
[Presentation] イメージングが拓くT細胞活性化の時空間的制御機構－シグナルソームの視点から免疫チェックポイントを解釈する－2017
- Author(s)
  横須賀忠
- Organizer
  Expert Seminar of Immunology
- Invited
- Data Source
  KAKENHI-PLANNED-16H06501
[Presentation] イメージングが拓くT細胞活性化の時空間的制御機構ーT細胞シグナルソームの視点から免疫チェックポイント分子を解釈するー2017
- Author(s)
  横須賀忠
- Organizer
  Meet The Specialist 2017
- Invited
- Data Source
  KAKENHI-PLANNED-16H06501
[Presentation] Microclusters as a signaling unit for T cell receptor endocytosis.2017
- Author(s)
  Machiyama H, Hata K, Yanase N, Hashimoto-Tane A, Saito T, Yokosuka T.
- Organizer
  The 7th International Symposium of Kyoto T Cell Conference
- Place of Presentation
  京都大学（京都府）
- Year and Date
  2017-03-13
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06501
[Presentation] イメージングが拓く免疫チェックポイント分子によるT細胞活性化の時空間的制御機構2017
- Author(s)
  横須賀忠
- Organizer
  上総イムノオンコロジーセミナー
- Invited
- Data Source
  KAKENHI-PROJECT-17H03600
[Presentation] イメージンブが拓くT細胞活性化の時空間的制御機構2017
- Author(s)
  横須賀忠
- Organizer
  Expert Seminar of Immunology
- Invited
- Data Source
  KAKENHI-INTERNATIONAL-16K21731
[Presentation] イメージングが拓く免疫チェックポイント分子によるT細胞活性化の時空間的制御機構2017
- Author(s)
  横須賀忠
- Organizer
  上総イムノオンコロジーセミナー
- Invited
- Data Source
  KAKENHI-PLANNED-16H06501
[Presentation] イメージングが拓く免疫チェックポイント分子による細胞活性化の時空間的制御機構2017
- Author(s)
  横須賀忠
- Organizer
  第32回日本肺癌学会ワークショップ
- Invited
- Data Source
  KAKENHI-PROJECT-17H03600
[Presentation] イメージングが拓く免疫チェックポイント分子によるT細胞活性化の時空間的制御機構2017
- Author(s)
  横須賀忠
- Organizer
  第14回日本免疫治療学研究会学術集会
- Place of Presentation
  東京大学（東京都・文京区）
- Year and Date
  2017-02-11
- Data Source
  KAKENHI-ORGANIZER-16H06495
[Presentation] B細胞の分化・機能におけるアルギニンメチル化酵素PRMT1の役割の解析2016
- Author(s)
  秦喜久美、矢那瀬紀子、水口純一郎、横須賀忠
- Organizer
  第26回京都T細胞カンファランス
- Place of Presentation
  大津
- Year and Date
  2016-05-20
- Data Source
  KAKENHI-PUBLICLY-15H01194
[Presentation] Balance of T cell activation and suppression controlled by Cbl-b-mediated ubiquitination of TCR microclusters2016
- Author(s)
  Tadashi Yokosuka
- Organizer
  MEXT Research Project Symposium
- Place of Presentation
  理化学研究所（横浜）
- Year and Date
  2016-03-02
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01194
[Presentation] Microclusters as a functional unit for the endocytosis of TCRs2016
- Author(s)
  Yokosuka T, Machiyama H, Hata K, Yanase N, Hashimoto-Tane A, Saito T.
- Organizer
  第45回日本免疫学会学術集会
- Place of Presentation
  沖縄コンベンションセンター（沖縄・宜野湾市）
- Year and Date
  2016-12-06
- Data Source
  KAKENHI-INTERNATIONAL-16K21731
[Presentation] Microclusters as a functional unit for the endocytosis of TCRs2016
- Author(s)
  Yokosuka T, Machiyama H, Hata K, Yanase N, Hashimoto-Tane A, Saito T.
- Organizer
  第45回日本免疫学会学術集会
- Place of Presentation
  沖縄コンベンションセンター（沖縄県・宜野湾市）
- Year and Date
  2016-12-06
- Data Source
  KAKENHI-ORGANIZER-16H06495
[Presentation] Microclusters as a functional unit for the endocytosis of TCRs2016
- Author(s)
  Yokosuka T, Machiyama H, Hata K, Yanase N, Hashimoto-Tane A, Saito T.
- Organizer
  第45回日本免疫学会学術集会
- Place of Presentation
  沖縄コンベンションセンター（沖縄）
- Year and Date
  2016-12-06
- Data Source
  KAKENHI-PLANNED-16H06501
[Presentation] Balance of T cell activation and suppression controlled by Cbl-b-mediated ubiquitination of TCR microclusters2016
- Author(s)
  Tadashi Yokosuka
- Organizer
  MEXT Research Project Symposium
- Place of Presentation
  理化学研究所（横浜）
- Year and Date
  2016-03-02
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24590590
[Presentation] Cytoskeletal regulation of the clustering of a Ras-GEF, RasGRP1, upon T cell activation2015
- Author(s)
  Tadashi Yokosuka, Akiko Hashimoto-Tane, Masae Furuhata, Hiroko Toyoda, Takashi Saito
- Organizer
  第44回日本免疫学会総会学術集会
- Place of Presentation
  札幌コンベンションセンター（札幌）
- Year and Date
  2015-11-18
- Data Source
  KAKENHI-PUBLICLY-15H01194
[Presentation] 分子イメージングが拓くT細胞活性化の時空間的制御機構2015
- Author(s)
  横須賀忠
- Organizer
  第14回四国免疫フォーラム
- Place of Presentation
  愛媛大学（松山）
- Year and Date
  2015-06-20
- Invited
- Data Source
  KAKENHI-PROJECT-24590590
[Presentation] Cytoskeletal regulation of the clustering of a Ras-GEF, RasGRP1, upon T cell activation2015
- Author(s)
  Tadashi Yokosuka, Akiko Hashimoto-Tane, Takashi Saito
- Organizer
  第25回京都T細胞カンファランス
- Place of Presentation
  京都大学（京都）
- Year and Date
  2015-05-15
- Data Source
  KAKENHI-PROJECT-24590590
[Presentation] Cytoskeletal regulation of the clustering of a Ras-GEF, RasGRP1, upon T cell activation2015
- Author(s)
  Tadashi Yokosuka, Akiko Hashimoto-Tane, Takashi Saito
- Organizer
  第25回京都T細胞カンファランス
- Place of Presentation
  京都大学（京都）
- Year and Date
  2015-05-15
- Data Source
  KAKENHI-PUBLICLY-15H01194
[Presentation] Cytoskeletal regulation of the clustering of a Ras-GEF, RasGRP1, upon T cell activation2015
- Author(s)
  Tadashi Yokosuka, Akiko Hashimoto-Tane, Masae Furuhata, Hiroko Toyoda, Takashi Saito
- Organizer
  第44回日本免疫学会総会学術集会
- Place of Presentation
  札幌コンベンションセンター（札幌）
- Year and Date
  2015-11-18
- Data Source
  KAKENHI-PROJECT-24590590
[Presentation] 分子イメージングが拓くT細胞活性化の時空間的制御機構2015
- Author(s)
  横須賀忠
- Organizer
  第14回四国免疫フォーラム
- Place of Presentation
  愛媛大学（松山）
- Year and Date
  2015-06-20
- Invited
- Data Source
  KAKENHI-PUBLICLY-15H01194
[Presentation] Distinct signalosome formation by two Ras-GEFs to activate the Ras-MAPK pathway in T cell signaling2013
- Author(s)
  Tadashi Yokosuka, Akiko Hashimoto-Tane, Takashi Saito
- Organizer
  第42回日本免疫学会総会学術集会
- Place of Presentation
  幕張メッセ（千葉）
- Data Source
  KAKENHI-PUBLICLY-25113725
[Presentation] Distinct signalosome formation by two Ras-GEFs to activate the Ras-MAPK pathway in T cell signaling2013
- Author(s)
  Tadashi Yokosuka, Akiko Hashimoto-Tane, Takashi Saito
- Organizer
  第42回日本免疫学会総会学術集会
- Place of Presentation
  幕張メッセ（千葉）
- Data Source
  KAKENHI-PROJECT-24590590
[Presentation] Negative costimulatory microclusters inhibiting T cell-mediated inflammation2013
- Author(s)
  Tadashi Yokosuka, Akiko Hashimoto-Tane, Takashi Saito
- Organizer
  JST-CREST International Symposium
- Place of Presentation
  学術総合センター（東京）
- Year and Date
  2013-02-12
- Data Source
  KAKENHI-PUBLICLY-23113521
[Presentation] Negative costimulatory microclusters inhibiting T cell-mediated inflammation2013
- Author(s)
  Tadashi Yokosuka, Akiko Hashimoto-Tane, Takashi Saito
- Organizer
  JST-CREST International Symposium
- Place of Presentation
  学術総合センター（東京）
- Data Source
  KAKENHI-PROJECT-24590590
[Presentation] Arp2/3 complex-mediated actin-nucleation supports T cell receptor microcluster2013
- Author(s)
  Akiko Hashimoto-Tane, Tadashi Yokosuka, Takashi Saito
- Organizer
  第42回日本免疫学会総会学術集会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-24590590
[Presentation] Dynamic and cytoskeletal regulation of T cell activation2013
- Author(s)
  Takashi Saito, Tadashi Yokosuka, Akiko Hashimoto-Tane
- Organizer
  RIKEN RCAI-University of Michigan Joint Workshop
- Place of Presentation
  Detroit, USA
- Invited
- Data Source
  KAKENHI-PROJECT-24590590
[Presentation] Basilic, a lymphoid-specific protein essential for CD28 costimulation and regulatory T cell development2013
- Author(s)
  Marie Malissen, Yinming Liangv, Margot Cucchetti, Romain Roncagalli, Tadashi Yokosuka, Takashi Saito, Christoph Wulfing, Bernard Malissen,
- Organizer
  International Congress of Immunology 2013
- Place of Presentation
  Italia Milano
- Data Source
  KAKENHI-PROJECT-24590590
[Presentation] Arp2/3 complex-mediated actin-nucleation supports T cell receptor microcluster2013
- Author(s)
  kiko Hashimoto-Tane, Tadashi Yokosuka, Takashi Saito
- Organizer
  第42回日本免疫学会総会学術集会
- Place of Presentation
  幕張メッセ（千葉）
- Data Source
  KAKENHI-PUBLICLY-25113725
[Presentation] Basilic, a lymphoid-specific protein essential for CD28 costimulation and regulatory T cell development2013
- Author(s)
  Marie Malissen, Yinming Liangv, Margot Cucchetti, Romain Roncagalli, Tadashi Yokosuka, Takashi Saito, Christoph Wulfing, Bernard Malissen
- Organizer
  International Congress of Immunology 2013
- Place of Presentation
  Italia Milano
- Data Source
  KAKENHI-PUBLICLY-25113725
[Presentation] Dynamic and cytoskeletal regulation of T cell activation2013
- Author(s)
  Takashi Saito, Tadashi Yokosuka, Akiko Hashimoto-Tane
- Organizer
  RIKEN RCAI-University of Michigan Joint Workshop
- Place of Presentation
  Detroit, USA
- Year and Date
  2013-01-16
- Invited
- Data Source
  KAKENHI-PUBLICLY-23113521
[Presentation] Negative regulation of TCR signaling by PD-1 microcluster2012
- Author(s)
  Yokosuka, T., Saito, T.
- Organizer
  Keystone Symposia-Regulation of Lymphocyte Signaling
- Place of Presentation
  Keystone, CO, USA(招待講演)
- Year and Date
  2012-03-15
- Data Source
  KAKENHI-PROJECT-19109005
[Presentation] 免疫シナプス形成を担うダイニンによるT細胞抗原受容体運搬の分子機構2012
- Author(s)
  多根(橋本)彰子、横須賀忠、斉藤隆
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  京都
- Year and Date
  2012-03-08
- Data Source
  KAKENHI-PROJECT-21590548
[Presentation] Ｔ細胞の抗原認識と免疫応答を司る活性化シグナルユニットの研究2012
- Author(s)
  横須賀忠
- Organizer
  第４回千葉医学会賞受賞講演
- Place of Presentation
  千葉大学医学部（千葉）
- Year and Date
  2012-06-20
- Invited
- Data Source
  KAKENHI-PUBLICLY-23113521
[Presentation] Negative regulation of TCR signaling by PD-1 microclusters2012
- Author(s)
  Yokosuka T, Saito T
- Organizer
  The 4th Joint RCAI-LIAI Workshop
- Place of Presentation
  La Jolla, CA. USA
- Year and Date
  2012-07-08
- Data Source
  KAKENHI-PROJECT-21590548
[Presentation] Essential role for intra- and intermolecular SH3-GUK interactions of CARMA1 in antigen receptor-induced NF-κB and JNK activation2012
- Author(s)
  Hiromitsu Hara, Tadashi Yokosuka, Hideki Hirakawa, Chitose Ishihara, Shinsuke Yasukawa, Haruhiko Koseki, Hiroki Yoshida, Takashi Saito
- Organizer
  第41回日本免疫学会総会学術集会
- Place of Presentation
  神戸国際会議場（神戸）
- Data Source
  KAKENHI-PROJECT-24590590
[Presentation] Negative regulation of TCR signaling by PD-1 microcluster2012
- Author(s)
  Yokosuka, T. and Saito, T
- Organizer
  Keystone Symposia-Regulation of Lymphocyte Signaling
- Place of Presentation
  Keystone, CO. USA
- Year and Date
  2012-03-15
- Data Source
  KAKENHI-PROJECT-19109005
[Presentation] Negative regulation of TCR signaling by PD-1 microcluster2012
- Author(s)
  Yokosuka T, Saito T
- Organizer
  Keystone Symposia-Regulation of Lymphocyte Signaling
- Place of Presentation
  Keystone, CO. USA
- Data Source
  KAKENHI-PROJECT-21590548
[Presentation] Essential role for intra- and intermolecular SH3-GUK interactions of CARMA1 in antigen receptor-induced NF-κB and JNK activation2012
- Author(s)
  Hiromitsu Hara, Tadashi Yokosuka, Hideki Hirakawa, Chitose Ishihara, Shinsuke Yasukawa, Haruhiko Koseki, Hiroki Yoshida, Takashi Saito
- Organizer
  第41回日本免疫学会総会学術集会
- Place of Presentation
  神戸国際会議場（神戸）
- Year and Date
  2012-12-05
- Data Source
  KAKENHI-PUBLICLY-23113521
[Presentation] The PD-1 microclusters : negative costimulatory signalosomes directly targeting TCR downstream2011
- Author(s)
  Yokosuka T, Saito T
- Organizer
  第40回日本免疫学会総会学術集会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-21590548
[Presentation] Dynamic regulation of T cell activation by TCR microclusters2011
- Author(s)
  Tadashi Yokosuka
- Organizer
  2nd CSI/JSI/KAI Joint symposium on Immunology
- Place of Presentation
  大阪(招待講演)
- Year and Date
  2011-12-06
- Data Source
  KAKENHI-PUBLICLY-23113521
[Presentation] Imaging of T cell activation regulation :-Negative regulation of TCR signaling by PD-1 microcluster-2011
- Author(s)
  Yokosuka T, Saito T
- Organizer
  University of Michigan-RCAI Joint Workshop
- Place of Presentation
  Yokohama
- Data Source
  KAKENHI-PROJECT-21590548
[Presentation] Dynamic regulation of T cell activation by TCR microclusters2011
- Author(s)
  Yokosuka, T.
- Organizer
  2^<nd> CSI/JSI/KAI Joint Symposium on Immunology "Regulation of Immune Responses in Health and Diseases"
- Place of Presentation
  Osaka(日中韓免疫シンポジウム)(招待講演)
- Year and Date
  2011-12-06
- Data Source
  KAKENHI-PROJECT-19109005
[Presentation] Dynamic regulation of T-cell activation by TCR microclusters2011
- Author(s)
  Yokosuka T
- Organizer
  RIKEN 2011 Joint Retreat
- Place of Presentation
  Kakegawa
- Data Source
  KAKENHI-PROJECT-21590548
[Presentation] 分子イメージングが拓くT細胞活性化の制御機構2011
- Author(s)
  横須賀忠
- Organizer
  第20回日本バイオイメージング学会学術集会
- Place of Presentation
  千歳(招待講演)
- Year and Date
  2011-09-02
- Data Source
  KAKENHI-PROJECT-19109005
[Presentation] 免疫シナプスにおけるダイニンによるT細胞受容体ミクロクラスター運搬の分子機構2011
- Author(s)
  多根(橋本)彰子、横須賀忠、斉藤隆
- Organizer
  第40回日本免疫学会総会学術集会
- Place of Presentation
  千葉
- Year and Date
  2011-11-29
- Data Source
  KAKENHI-PROJECT-19109005
[Presentation] PD-1マイクロクラスターによるT細胞活性化制御機構の解明2011
- Author(s)
  横須賀忠
- Organizer
  第21回Kyoto T Cell Conference
- Place of Presentation
  京都
- Year and Date
  2011-06-10
- Data Source
  KAKENHI-PUBLICLY-23113521
[Presentation] Dynein-driven transport of TCR microclusters forms Immune synapse and regulates T cell activation2011
- Author(s)
  Hashimoto-Tane A, Yokosuka T, Sakuma M, Saito T.
- Organizer
  第84回日本薬理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21590548
[Presentation] The PD-1 microclusters : negative costimulatory signalosome directly targeting TCR downstream2011
- Author(s)
  Tadashi Yokosuka
- Organizer
  第40回日本免疫学会総会学術集会
- Place of Presentation
  千葉(招待講演)
- Year and Date
  2011-11-28
- Data Source
  KAKENHI-PUBLICLY-23113521
[Presentation] PD-1マイクロクラスターによるT細胞活性化制御機構の解明2011
- Author(s)
  横須賀忠
- Organizer
  第21回Kyoto T Cell Conference
- Place of Presentation
  京都
- Year and Date
  2011-06-10
- Data Source
  KAKENHI-PROJECT-21590548
[Presentation] 分子イメージングが拓くT細胞活性化の制御機構2011
- Author(s)
  横須賀忠
- Organizer
  第20回日本バイオイメージング学会学術集会
- Place of Presentation
  千歳
- Data Source
  KAKENHI-PROJECT-21590548
[Presentation] 分子イメージングが拓くT細胞活性化の制御機構2011
- Author(s)
  横須賀忠
- Organizer
  第20回日本バイオイメージング学会学術集会
- Place of Presentation
  千歳(招待講演)
- Year and Date
  2011-09-02
- Data Source
  KAKENHI-PROJECT-21590548
[Presentation] Dynamic regulation of T cell activation by TCR microclusters2011
- Author(s)
  Yokosuka T
- Organizer
  2nd CSI/JSI/KAI Joint Symposium on Immunology "Regulation of Immune Responses in Health and Diseases"
- Place of Presentation
  Osaka
- Data Source
  KAKENHI-PROJECT-21590548
[Presentation] Spatiotemporal regulation of T cell activation and costimulation2011
- Author(s)
  Saito T, Yokosuka T, Hashimoto-Tane A.
- Organizer
  1st POSTECH International Symposium of Bio-Imaging
- Place of Presentation
  Pohang, Korea
- Data Source
  KAKENHI-PROJECT-21590548
[Presentation] The PD-1 microclusters : negative costimulatory signalosome directly targeting TCR downstream2011
- Author(s)
  Tadashi Yokosuka
- Organizer
  第40回日本免疫学会総会学術集会
- Place of Presentation
  千葉(招待講演)
- Year and Date
  2011-11-28
- Data Source
  KAKENHI-PROJECT-21590548
[Presentation] 免疫シナプスにおけるダイニンによるT細胞受容体ミクロクラスター運搬の分子機構2011
- Author(s)
  多根(橋本)彰子、横須賀忠、斉藤隆
- Organizer
  第40回日本免疫学会総会学術集会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-21590548
[Presentation] Dynamic Regulation of T-cell Activation by TCR Microclusters2011
- Author(s)
  Yokosuka T
- Organizer
  東京理科大学生命科学研究所セミナー
- Place of Presentation
  野田
- Year and Date
  2011-01-11
- Data Source
  KAKENHI-PROJECT-21590548
[Presentation] SH3-Guk domain regulating Carmal micro-cluster formation is essential for antigen receptor-induced NF-κB activation2011
- Author(s)
  Hara, H., Yokosuka, T., et al
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PROJECT-19109005
[Presentation] PD-1マイクロクラスターによるT細胞活性化制御機構の解明2011
- Author(s)
  横須賀忠
- Organizer
  Kyoto T Cell Conference
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-21590548
[Presentation] Spatiotemporal regulation of T cell co-stimulation2011
- Author(s)
  Saito T, Yokosuka T, Tane-Hashimoto A.
- Organizer
  FASEB Summer Conferences Signal Transduction in the Immune System
- Place of Presentation
  Snowmass Village, CO
- Data Source
  KAKENHI-PROJECT-21590548
[Presentation] 分子イメージングが拓くT細胞活性化の制御機構2011
- Author(s)
  横須賀忠
- Organizer
  第20回日本バイオイメージング学会学術集会
- Place of Presentation
  千歳(招待講演)
- Year and Date
  2011-09-02
- Data Source
  KAKENHI-PUBLICLY-23113521
[Presentation] SH3-Guk domain regulating Carma1 micro-cluster formation is essential for antigen receptor-induced NF-κB activation2011
- Author(s)
  Hara H, Yokosuka T, Ishihara C, Yasukawa S, Hirakawa H, Iizasa E, Yoshida H, Saito T.
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  Yokohama
- Data Source
  KAKENHI-PROJECT-21590548
[Presentation] Visualising the dynamics of immune synapse by TIRF2011
- Author(s)
  Saito, T., Yokosuka, T., Tane-Hashimoto, A., Sakata-Sogawa, K., Tokunaga, M.
- Organizer
  XXVI Congress of the International Society for Advancement of Cytometry(CYTO2011)
- Place of Presentation
  Baltimore, MD, USA
- Year and Date
  2011-05-24
- Data Source
  KAKENHI-PROJECT-19109005
[Presentation] Dynamic regulation of T cell activation by TCR microclusters2011
- Author(s)
  Tadashi Yokosuka
- Organizer
  2nd CSI/JSI/KAI Joint symposium on Immunology
- Place of Presentation
  大阪(招待講演)
- Year and Date
  2011-12-06
- Data Source
  KAKENHI-PROJECT-21590548
[Presentation] A. Spatiotemporal regulation of T cell activation and costimulation2011
- Author(s)
  Saito, T., Yokosuka, T., Hashimoto-Tane
- Organizer
  1^<st> POSTECH International Symposium of Bio-Imaging
- Place of Presentation
  Pohang, Korea
- Year and Date
  2011-09-30
- Data Source
  KAKENHI-PROJECT-19109005
[Presentation] Visualising the dynamics of immune synapse by TIRF2011
- Author(s)
  Saito, T., Yokosuka, T., Tane-Hashimoto, A.
- Organizer
  XXVI Congress of the International Society for Advancement of Cytometry (CYTO2011)
- Place of Presentation
  Baltimore, MD, USA(招待講演)
- Year and Date
  2011-05-24
- Data Source
  KAKENHI-PROJECT-19109005
[Presentation] Visualising the dynamics of immune synapse by TIRF2011
- Author(s)
  Saito T, Yokosuka T, Tane-Hashimoto A, Sakata-Sogawa K, Tokunaga M.
- Organizer
  XXVI Congress of the International Society for Advancement of Cytometry(CYTO2011)
- Place of Presentation
  Baltimore, MD, USA
- Data Source
  KAKENHI-PROJECT-21590548
[Presentation] Spatiotemporal regulation of T cell activation and costimulation2011
- Author(s)
  Saito, T., Yokosuka, T., Tane-Hashimoto, A.
- Organizer
  1^<st> POSTECH International Symposium of Bio-Imaging
- Place of Presentation
  Pophang, Korea(招待講演)
- Year and Date
  2011-09-30
- Data Source
  KAKENHI-PROJECT-19109005
[Presentation] Spatiotemporal regulation of T cell co-stimulation2011
- Author(s)
  Saito, T., Yokosuka, T., Tane-Hashimoto, A.
- Organizer
  FASEB Summer Conferences-Signal Transduction in the Immune System
- Place of Presentation
  Snowmass Village, CO
- Year and Date
  2011-06-23
- Data Source
  KAKENHI-PROJECT-19109005
[Presentation] The PD-1 microclusters : negative costimulatory signalosomes directly targeting TCR downstream2011
- Author(s)
  Yokosuka, T., Saito, T.
- Organizer
  第40回日本免疫学会総会学術集会
- Place of Presentation
  千葉(招待講演)
- Year and Date
  2011-11-28
- Data Source
  KAKENHI-PROJECT-19109005
[Presentation] Spatiotemporal regulation of T cell co-stimulation2011
- Author(s)
  Saito, T., Yokosuka, T., Tane-Hashimoto, A.
- Organizer
  FASEB Summer Conferences-Signal Transduction in the Immune System
- Place of Presentation
  Snowmass Village, CO, USA(招待講演)
- Year and Date
  2011-06-23
- Data Source
  KAKENHI-PROJECT-19109005
[Presentation] Dynamic regulation of T-cell costimulation by TCR microclusters and the c-SMAC2010
- Author(s)
  Yokosuka T, Sakata-Sogawa K, Tokunaga M, Saito T
- Organizer
  14th International Congress of Immunology
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-21590548
[Presentation] Dynamic Regulation of T-cell Activation by TCR Microclusters2010
- Author(s)
  Tadashi Yokosuka
- Organizer
  第16回武田科学振興財団生命科学シンポジウム(The 16th Takeda Science Foundation Symposium on Bioscience)
- Place of Presentation
  東京
- Year and Date
  2010-12-01
- Data Source
  KAKENHI-PROJECT-21590548
[Presentation] 分子イメージングが拓くT細胞活性化の制御機構2010
- Author(s)
  横須賀忠
- Organizer
  第2回バイオフロンティアセミナー「免疫・疾患制御に向けたイメージング解析」
- Place of Presentation
  東京
- Year and Date
  2010-11-18
- Data Source
  KAKENHI-PROJECT-21590548
[Presentation] CRTAM confers late-stage activation of CD8+T cells to regulate retention within lymph node2010
- Author(s)
  Takeuchi A, Itoh A, Yokosuka T, Ogasawara K, Saito T
- Organizer
  14th International Congress of Immunology
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-21590548
[Presentation] Dynamic Regulation of T-cell Activation by TCR Microclusters2010
- Author(s)
  Yokosuka T, Saito T
- Organizer
  第16回武田科学振興財団生命科学シンポジウム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21590548
[Presentation] Dynamic regulation of T-cell costimulation by TCR microclusters and the c-SNAG2010
- Author(s)
  Tadashi Yokosuka
- Organizer
  14th International Congress of Immunology(第14回国際免疫学会議)
- Place of Presentation
  神戸
- Year and Date
  2010-08-23
- Data Source
  KAKENHI-PROJECT-21590548
[Presentation] Dynamic regulation of T-cell costimulation by TCR microclusters and the c-SMAC2010
- Author(s)
  Tadashi Yokosuka
- Organizer
  第13回国際細胞膜研究フォーラム/第6回iCeMS国際シンポジウム
- Place of Presentation
  京都市、ホテルフジタ京都
- Year and Date
  2010-01-27
- Data Source
  KAKENHI-PROJECT-21590548
[Presentation] Dynamic regulation of T-cell costimulation by TCR microclusters and the c-SMAC2010
- Author(s)
  Tadashi Yokosuka
- Organizer
  第13回国際細胞膜研究フォーラム/第6回iCeMS国際シンポジウム
- Place of Presentation
  京都
- Year and Date
  2010-01-27
- Data Source
  KAKENHI-PROJECT-19109005
[Presentation] T細胞の免疫シナプス形成と胸腺選択性との機能的相関の解析2010
- Author(s)
  横須賀忠、斉藤隆
- Organizer
  第20回Kyoto T Cell Conference(KTCC)学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-21590548
[Presentation] Dynein-mediated translocation of TCR microclusters along microtubules to form cSMAC2010
- Author(s)
  Hashimoto-Tane A, Yokosuka T, Saito T.
- Organizer
  Keystone Symposia(Breckenridge
- Place of Presentation
  CO. USA
- Data Source
  KAKENHI-PROJECT-21590548
[Presentation] Dynamic regulation of T-cell costimulation by TCR microclusters and the c-SMAC2010
- Author(s)
  Yokosuka T
- Organizer
  The 13th International Membrane Research Forum/The 6th iCeMS International Symposium, Featuring Membrane Meso Mechanisms
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-21590548
[Presentation] Dynein-mediated translocation of TCR microclusters along microtubules to form c-SMAC during T cell activation2010
- Author(s)
  Hashimoto-Tane A, Yokosuka T, Sakuma M, Saito T.
- Organizer
  14th International Congress of Immunology
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-21590548
[Presentation] Dynamic regulation of T cell co-stimulation by TCR-CD28 microclusters2009
- Author(s)
  Yokosuka, T.
- Organizer
  LIAI-RCAI Joint Workshop 2009
- Place of Presentation
  横浜
- Year and Date
  2009-01-07
- Data Source
  KAKENHI-PROJECT-19109005
[Presentation] Dynamic regulation of T-cell costimulation by TCR microclusters2009
- Author(s)
  Tadashi Yokosuka
- Organizer
  FASEB Summer Research Conferences
- Place of Presentation
  Snowmass Village(USA)
- Year and Date
  2009-06-24
- Data Source
  KAKENHI-PROJECT-21590548
[Presentation] Dynamic Regulation of T Cell Co-stimulation by TCR-CD28 Microclusters2009
- Author(s)
  Yokosuka, T.
- Organizer
  LIAI-RCAI Joint Workshop 2009-Regulation of Lymphocyte Function and Immune Responses
- Place of Presentation
  横浜
- Year and Date
  2009-01-07
- Data Source
  KAKENHI-PROJECT-19590504
[Presentation] Dynamic regulation of T-cell costimulation by TCR microclusters and the c-SMAC2009
- Author(s)
  Tadashi Yokosuka
- Organizer
  第39回日本免疫学会総会・学術集会
- Place of Presentation
  大阪市国際会議場
- Year and Date
  2009-12-03
- Data Source
  KAKENHI-PROJECT-21590548
[Presentation] Dynamic assembly of signaling complex for positive and negative costimulation of T cell activation2009
- Author(s)
  Yokosuka T and Saito T
- Organizer
  The 5th International Workshop of Kyoto T Cell
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-21590548
[Presentation] Dynamic regulation of T-cell costimulation by TCR microclusters and the c-SMAC2009
- Author(s)
  Tadashi Yokosuka
- Organizer
  第39回日本免疫学会総会・学術集会
- Place of Presentation
  大阪
- Year and Date
  2009-12-03
- Data Source
  KAKENHI-PROJECT-19109005
[Presentation] Imaging of Immune Responses Dynamic regulation of T-cell costimulation by TCR microclusters and the c-SMAC2009
- Author(s)
  Yokosuka T, Saito T
- Organizer
  第39回日本免疫学会総会・学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-21590548
[Presentation] T細胞活性化及びcSMAC形成につながる微小管モーター・ダイニンによるTCRミクロクラスターの移動2009
- Author(s)
  橋本彰子(多根)、横須賀忠、斉藤隆
- Organizer
  第39回日本免疫学会総会・学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-21590548
[Presentation] Dynamic regulation of T-cell costimulation by TCR microclusters2009
- Author(s)
  Tadashi Yokosuka
- Organizer
  FASEB Summer Research Conferences-Signal Transduction in the Immune System
- Place of Presentation
  Snowmass Village(USA)
- Year and Date
  2009-06-24
- Data Source
  KAKENHI-PROJECT-19109005
[Presentation] TCR microclusters move along microtubules in early T cell activation2009
- Author(s)
  Hashimoto-Tane A, Yokosuka T, Ishihara C, Saito T.
- Organizer
  The 5th International Workshop of Kyoto T Cell Conference
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-21590548
[Presentation] Dynamic regulation of T-cell costimulation by TCR microclusters2009
- Author(s)
  Yokosuka T, Saito T
- Organizer
  FASEB Summer Research Conferences
- Place of Presentation
  Snowmass Village, CO
- Data Source
  KAKENHI-PROJECT-21590548
[Presentation] Identification of a region in immunological synapse critical for T cell co-stimulation2008
- Author(s)
  Yokosuka, T.
- Organizer
  第38回日本免疫学会総会・学術集会
- Place of Presentation
  京都
- Year and Date
  2008-12-03
- Data Source
  KAKENHI-PROJECT-19109005
[Presentation] Visualization of signaling complex upon T cell activation2008
- Author(s)
  Yokosuka, T.
- Organizer
  The 2nd joint symposium between immunology and imaging, WIP-iFReC,
- Place of Presentation
  大阪
- Year and Date
  2008-08-28
- Data Source
  KAKENHI-PROJECT-19590504
[Presentation] T細胞の副刺激を制御する免疫シナプスの領域の同定/ Identification of a region in immunological synapse critical for T cell co-stimulation2008
- Author(s)
  Yokosuka, T., Sogawa-Sakata, K., Tane-Hashimoto, A., Tokunaga, M., Dustine, ML., Saito, T.
- Organizer
  第38回日本免疫学会総会・学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19590504
[Presentation] Dynamic Regulation of T Cell Co-stimulation by TCR-CD28 Microclusters2008
- Author(s)
  Yokosuka, T. and Saito, T
- Organizer
  RCAI-JSI International Symposium on Immunology 2008 : Regulation of Immune Homeostasis and Diseases
- Place of Presentation
  Yokohama
- Year and Date
  2008-06-26
- Data Source
  KAKENHI-PROJECT-19109005
[Presentation] T細胞の副刺激を制御する免疫シナプスの領域の同定/Identification of a region in immunological synapse critical for T cell co-stimulation2008
- Author(s)
  Yokosuka, T.
- Organizer
  第38回日本免疫学会総会・学術集会
- Place of Presentation
  京都
- Year and Date
  2008-12-03
- Data Source
  KAKENHI-PROJECT-19590504
[Presentation] TCR-CD28マイクロクラスターとc-SMACによるT細胞活性化の時空間的制御/Spatiotemporal regulations of T cell activation by a c-SMAC and TCR-CD28-microclusters2007
- Author(s)
  Yokosuka, T.
- Organizer
  第37回日本免疫学会総会・学術集会
- Place of Presentation
  東京
- Year and Date
  2007-11-21
- Data Source
  KAKENHI-PROJECT-19590504
[Presentation] Spatiotemporal regulation of T cell activation by TCR-CD28-microclusters2007
- Author(s)
  Yokosuka, T.
- Organizer
  第7回日本蛋白質科学会年会(The7^<th>Annual Meeting of Protein Science Society of Japan)
- Place of Presentation
  仙台
- Year and Date
  2007-05-25
- Data Source
  KAKENHI-PROJECT-19590504
[Presentation] TCR-CD28-マイクロクラスターによるT細胞活性化の時空間的制御2007
- Author(s)
  横須賀忠
- Organizer
  第7回日本蛋白質科学会年会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-19590504
[Presentation] Spatiotemporal regulation of T cell activation by TCR-CD28-microclusters2007
- Author(s)
  Yokosuka, T.
- Organizer
  第10回国際細胞膜研究フォーラム
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19590504
[Presentation] TCR-CD28マイクロクラスターによるT細胞活性化の時空間的制御2007
- Author(s)
  横須賀忠
- Organizer
  第17回Kyoto T Cell Coference(KTCC)学術集会
- Place of Presentation
  京都
- Year and Date
  2007-06-15
- Data Source
  KAKENHI-PROJECT-19109005
[Presentation] Spatiotemporal regulation of T cell activation by TCR-CD28-microclusters2007
- Author(s)
  Yokosuka, T.
- Organizer
  13^<th>International Congress of Immunology
- Place of Presentation
  Rio de Janeiro,Brazil
- Year and Date
  2007-08-21
- Data Source
  KAKENHI-PROJECT-19590504
[Presentation] TCR-CD28マイクロクラスターによるT細胞活性化の時空間的制御2007
- Author(s)
  横須賀忠
- Organizer
  第17回Kyoto T Cell Coference(KTCC)学術集会
- Place of Presentation
  京都
- Year and Date
  2007-06-15
- Data Source
  KAKENHI-PROJECT-19590504
[Presentation] Spatiotemporal regulation of lymphocyte activation-Signalsome,TCR-microcluster-2007
- Author(s)
  Yokosuka, T.
- Organizer
  National Academy of Engineering 2007 Japan-America Frontiers of Engineering Symposium(第7回日米先端工学シンポジウム)
- Place of Presentation
  California,USA
- Year and Date
  2007-11-05
- Data Source
  KAKENHI-PROJECT-19590504
[Presentation] Spatiotemporal regulation of lymphocyte activation-Signalsome,TCR-microcluster-2007
- Author(s)
  Yokosuka, T.
- Organizer
  2007Japan-America Frontiers of Engineering Symposium
- Place of Presentation
  Palo Alto,USA
- Data Source
  KAKENHI-PROJECT-19109005
[Presentation] Spatiotemporal regulation of T cell activation by TCR-CD28-microclusters2007
- Author(s)
  Yokosuka, T.
- Organizer
  FASEB Summer Research Conferences-Signal Transduction in the Immune System
- Place of Presentation
  Snowmass,USA
- Data Source
  KAKENHI-PROJECT-19109005
[Presentation] Spatiotemporal regulation of T cell activation by TCR-CD28-microclusters2007
- Author(s)
  Yokosuka, T., Sakata-Sogawa, K. Kobayashi, W., Hiroshima, M., Hashimoto-Tane, A., Tokunaga, M., Dustine M.L. and Saito, T. (Minisymposium) (20070821)
- Organizer
  13th International Congress of Immunology
- Place of Presentation
  リオデジャネイロ
- Data Source
  KAKENHI-PROJECT-19590504
[Presentation] Spatiotemporal regulation of T cell activation by TCR-CD28-microclusters2007
- Author(s)
  Yokosuka, T.
- Organizer
  13^<th> International Congress of Immunology
- Place of Presentation
  Rio de Janeiro,Brazil
- Year and Date
  2007-08-21
- Data Source
  KAKENHI-PROJECT-19109005
[Presentation] Spatiotemporal regulation of lymphocyte activation: Signalsome, TCR-microcluster2007
- Author(s)
  Yokosuka, T.
- Organizer
  National Academy of Engineering 2007 Japan-America Frontiers of Engineering Symposium 第7回日米先端工学シンポジウム
- Place of Presentation
  パロアルト
- Data Source
  KAKENHI-PROJECT-19590504
[Presentation] TCR-CD28マイクロクラスターとc-SMACによるT細胞活性化の時空間的制御Spatiotemporal regulations of T cell activation by a c-SMAC and TCR-CD28-microclusters2007
- Author(s)
  Yokosuka, T., Sakata-Sogawa, Hashimoto-Tane, A., Tokunaga, M., Dustin, ML. and Saito, T.
- Organizer
  第37回日本免疫学会総会・学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19590504
[Presentation] Spatiotemporal regulation of T cell activation by TCR-CD28-microclusters2007
- Author(s)
  Yokosuka, T.
- Organizer
  FASEB Summer Research Conferences
- Place of Presentation
  Colorado,USA
- Year and Date
  2007-06-26
- Data Source
  KAKENHI-PROJECT-19590504
[Presentation] Spatiotemporal regulation of T cell activation by TCR-CD28-microclusters2007
- Author(s)
  Yokosuka, T.
- Organizer
  第7回日本蛋白質科学会年会
- Place of Presentation
  仙台
- Year and Date
  2007-05-25
- Data Source
  KAKENHI-PROJECT-19109005
[Presentation] TCR-CD28マイクロクラスターとc-SMACによるT細胞活性化の時空間的制御2007
- Author(s)
  横須賀忠
- Organizer
  第37回日本免疫学会総会・学術集会
- Place of Presentation
  東京
- Year and Date
  2007-11-21
- Data Source
  KAKENHI-PROJECT-19109005
[Presentation] Spatiotemporal regulation of lymphocyte activation : Signalsome2007
- Author(s)
  Yokosuka, T
- Organizer
  TCR-microcluster. National Academy of Engineering 2007 Japan-America Frontiers of Engineering Symposium
- Place of Presentation
  Palo Alto, CA
- Data Source
  KAKENHI-PROJECT-19109005
[Presentation] “Microsynapse” structure supporting TCR microclusters augments T cell activation
- Author(s)
  Akiko Hashimoto-Tane, Tadashi Yokosuka, Takashi Saito
- Organizer
  第42回日本免疫学会総会学術集会
- Place of Presentation
  京都国際会議場（京都）
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-24590590
[Presentation] Molecular imaging unveils the dynamic regulation of T cell activation
- Author(s)
  Tadashi Yokosuka, Akiko Hashimoto-Tane, Takashi Saito
- Organizer
  第18回日本がん免疫学会総会
- Place of Presentation
  ひめ銀ホール（松山）
- Year and Date
  2014-07-30 – 2014-08-01
- Invited
- Data Source
  KAKENHI-PROJECT-24590590
[Presentation] Subcellular imaging of the E3 ubiquitin ligases, c-Cbl and Cbl-b, to control T cell activation signals through ubiquitin clustering at TCR microclusters
- Author(s)
  Tadashi Yokosuka, Akiko Hashimoto-Tane, Takashi Saito
- Organizer
  第42回日本免疫学会総会学術集会
- Place of Presentation
  京都国際会議場（京都）
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PUBLICLY-25113725
[Presentation] Molecular imaging unveils the dynamic regulation of T cell activation
- Author(s)
  Tadashi Yokosuka, Akiko Hashimoto-Tane, Takashi Saito
- Organizer
  第18回日本がん免疫学会総会
- Place of Presentation
  ひめ銀ホール（松山）
- Year and Date
  2014-07-30 – 2014-08-01
- Invited
- Data Source
  KAKENHI-PUBLICLY-25113725
[Presentation] Distinct signalosome formation by two Ras-GEFs to activate the Ras-MAPK pathway in T cell signaling
- Author(s)
  Tadashi Yokosuka, Akiko Hashimoto-Tane, Takashi Saito
- Organizer
  第24回京都T細胞カンファランス
- Place of Presentation
  京都大学（京都）
- Year and Date
  2014-05-16 – 2014-05-17
- Data Source
  KAKENHI-PROJECT-24590590
[Presentation] Subcellular imaging of the E3 ubiquitin ligases, c-Cbl and Cbl-b, to control T cell activation signals through ubiquitin clustering at TCR microclusters
- Author(s)
  Tadashi Yokosuka, Akiko Hashimoto-Tane, Takashi Saito
- Organizer
  第42回日本免疫学会総会学術集会
- Place of Presentation
  京都国際会議場（京都）
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-24590590
[Presentation] Distinct signalosome formation by two Ras-GEFs to activate the Ras-MAPK pathway in T cell signaling
- Author(s)
  Tadashi Yokosuka, Akiko Hashimoto-Tane, Takashi Saito
- Organizer
  第24回京都T細胞カンファランス
- Place of Presentation
  京都大学（京都）
- Year and Date
  2014-05-16 – 2014-05-17
- Data Source
  KAKENHI-PUBLICLY-25113725
[Presentation] Ｔ細胞の抗原認識と免疫応答を司る活性化シグナルユニットの研究
- Author(s)
  横須賀忠
- Organizer
  第４回千葉医学会賞受賞講演
- Place of Presentation
  千葉大学医学部（千葉）
- Invited
- Data Source
  KAKENHI-PROJECT-24590590
[Presentation] “Microsynapse” structure supporting TCR microclusters augments T cell activation
- Author(s)
  Akiko Hashimoto-Tane, Tadashi Yokosuka, Takashi Saito
- Organizer
  第42回日本免疫学会総会学術集会
- Place of Presentation
  京都国際会議場（京都）
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PUBLICLY-25113725

1. MATSUMOTO Mitsuru (60221595)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. 町山裕亮 (40704606)

# of Collaborated Projects: 3 results

# of Collaborated Products: 56 results
3. 若松英 (40632617)

# of Collaborated Projects: 2 results

# of Collaborated Products: 33 results
4. 西嶋仁 (60425410)

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
5. SAITO Takashi (50205655)

# of Collaborated Projects: 1 results

# of Collaborated Products: 28 results
6. 末永忠広 (20396675)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 矢那瀬紀子 (10210303)

# of Collaborated Projects: 1 results

# of Collaborated Products: 21 results
8. 竹内新 (00360579)

# of Collaborated Projects: 1 results

# of Collaborated Products: 13 results
9. 東みゆき

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 竹馬俊介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

YOKOSUKA Tadashi 横須賀 忠

Research Projects

Research Products

Co-Researchers

Benefits of endogenous TCRs recognizing self antigens in CAR-T cell funcitonsPrincipal Investigator

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Development of the basis of the crosstalk between T cell costimulatory receptors and chimeric antigen receptorsPrincipal Investigator

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先端的分子イメージング法を基盤としたBiTE抗体療法の解析

Principal Investigator

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ネオ・セルフの生成・機能・構造

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Molecualr imaging for development of chimeric antigen receptors (CARs) resistant to T cell exhaustionPrincipal Investigator

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Signalosome formation and functions of the immune-checkpoint receptor TIGIT regulated by the height of its ectodomain.Principal Investigator

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Basic research for the development of a novel CAR-adaptor T cells by an advanced imaging systemPrincipal Investigator

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Comprehensive understanding of neo-self generation, function, and structure

Principal Investigator

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Research Institution

Analysis for neo-self in MHC-misfolded protein complexPrincipal Investigator

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Review Section

Research Institution

International support for the reseach activities for the production, function and structure of neo-self

Principal Investigator

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ユビキチンが形成するT細胞抑制性シグナルソームの分子イメージング解析Principal Investigator

Principal Investigator

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Research Institution

E3ユビキチンリガーゼの機能ドメイン形成によるT細胞活性化制御機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

Mechanism of T cell activation regulation by TCR microclusters and the costimulation network.Principal Investigator

Principal Investigator

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YOKOSUKA Tadashi 横須賀忠