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YOKOSUKA Tadashi  横須賀 忠

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Researcher Number 10359599
Other IDs
External Links
Affiliation (Current) 2022: 東京医科大学, 医学部, 主任教授
Affiliation (based on the past Project Information) *help 2016 – 2021: 東京医科大学, 医学部, 主任教授
2015 – 2016: 東京医科大学, 医学部, 教授
2013 – 2014: 独立行政法人理化学研究所, 統合生命医科学研究センター, 上級研究員
2006 – 2012: 独立行政法人理化学研究所, 免疫シグナル研究グループ, 上級研究員
2004 – 2005: 独立行政法人理化学研究所, 免疫シグナル研究グループ, 研究員
2003: 千葉大学, 大学院・医学研究院, 助手
Review Section/Research Field
Principal Investigator
Immunology / Biological Sciences / Tumor therapeutics / Basic Section 50020:Tumor diagnostics and therapeutics-related / Medium-sized Section 49:Pathology, infection/immunology, and related fields
Except Principal Investigator
Biological Sciences / Immunology
Keywords
Principal Investigator
シグナル伝達 / 免疫学 / 分子イメージング / 免疫シナプス / マイクロクラスター / T細胞受容体 / Tリンパ球 / T細胞活性化 / シグナルソーム / プレイナーメンブラン … More / SMAC / 補助刺激受容体 / 抗原認識 / リンパ球 / バイオイメージング / 受容体・細胞内シグナル伝達 / 獲得免疫 / 細胞療法 / T細胞 / キメラ抗原受容体 / 免疫チェックポイント / キラーT細胞 / 細胞傷害活性 / 細胞分裂 / 分化誘導 / サイトカインシグナル / ホメオスタシス増殖 / T細胞受容体シグナル / 細胞傷害性T細胞 / エフェクター / 癌 / MHC / ミスフォールド蛋白質 / ネオ・セルフ / TCR / 抗リン脂質抗体症候群 / 自己免疫疾患 / 自己抗体 / がん免疫 / キメラ抗原受容体T細胞 / 免疫チェックポイント分子 / 副刺激受容体 / TIGIT / シグナル伝達分子 / イメージング … More
Except Principal Investigator
免疫学的自己 / 免疫シナプス / ミクロクラスター / シグナル伝達 / 抗原認識 / T細胞 / 細胞活性化 / 副刺激 / 活性化シグナル / PD-i / ダイニン / 細胞骨格 / ミクロチューブル / イメージング解析 / TCR複合体 / 獲得免疫 / T細胞活性化 / 免疫学 / イメージング / 抗原認識機構 / 免疫的自己 / 連携強化 / 分子イメージング / 自己免疫疾患 / MHC / アレルギー / 構造生物学 / 国際共同研究 / ネオ・セルフ / HLA / T細胞抗原受容体 / 免疫認識機構 / 国際研究協力 Less
  • Research Projects

    (16 results)
  • Research Products

    (390 results)
  • Co-Researchers

    (18 People)
  •  ネオ・セルフの生成・機能・構造

    • Principal Investigator
      松本 満
    • Project Period (FY)
      2021
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokushima
  •  Molecualr imaging for development of chimeric antigen receptors (CARs) resistant to T cell exhaustionPrincipal Investigator

    • Principal Investigator
      横須賀 忠
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Tokyo Medical University
  •  Signalosome formation and functions of the immune-checkpoint receptor TIGIT regulated by the height of its ectodomain.Principal Investigator

    • Principal Investigator
      横須賀 忠
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 49:Pathology, infection/immunology, and related fields
    • Research Institution
      Tokyo Medical University
  •  Basic research for the development of a novel CAR-adaptor T cells by an advanced imaging systemPrincipal Investigator

    • Principal Investigator
      Yokosuka Tadashi
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Tumor therapeutics
    • Research Institution
      Tokyo Medical University
  •  ネオ・セルフの生成・機能・構造の総括的理解

    • Principal Investigator
      松本 満
    • Project Period (FY)
      2016 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokushima
  •  Analysis for neo-self in MHC-misfolded protein complexPrincipal Investigator

    • Principal Investigator
      横須賀 忠
    • Project Period (FY)
      2016 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Tokyo Medical University
  •  ネオ・セルフの生成・機能・構造に対する国際活動支援

    • Principal Investigator
      松本 満
    • Project Period (FY)
      2016 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokushima
  •  ユビキチンが形成するT細胞抑制性シグナルソームの分子イメージング解析Principal Investigator

    • Principal Investigator
      横須賀 忠
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Tokyo Medical University
  •  E3ユビキチンリガーゼの機能ドメイン形成によるT細胞活性化制御機構の解明Principal Investigator

    • Principal Investigator
      横須賀 忠
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      The Institute of Physical and Chemical Research
  •  Mechanism of T cell activation regulation by TCR microclusters and the costimulation network.Principal Investigator

    • Principal Investigator
      Yokosuka Tadashi
    • Project Period (FY)
      2012 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Immunology
    • Research Institution
      Tokyo Medical University
      The Institute of Physical and Chemical Research
  •  ユビキチン化と抑制性マイクロクラスターの分子イメージング解析Principal Investigator

    • Principal Investigator
      横須賀 忠
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      The Institute of Physical and Chemical Research
  •  Mechanisms of T cell activation regulation by inhibitory microclustersPrincipal Investigator

    • Principal Investigator
      YOKOSUKA Tadashi
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Immunology
    • Research Institution
      The Institute of Physical and Chemical Research
  •  Spatiotemporal regulation of antigen recognition and activation of T cells

    • Principal Investigator
      SAITO Takashi
    • Project Period (FY)
      2007 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Immunology
    • Research Institution
      The Institute of Physical and Chemical Research
  •  Positive and negative regulation of T-cell activation by costimulatory molecules through TCR microclustersPrincipal Investigator

    • Principal Investigator
      YOKOSUKA Tadashi
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Immunology
    • Research Institution
      The Institute of Physical and Chemical Research
  •  プレーナーメンブランを用いた細胞傷害性T細胞の自己認識機構の解明Principal Investigator

    • Principal Investigator
      横須賀 忠
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Immunology
    • Research Institution
      The Institute of Physical and Chemical Research
  •  細胞増殖を伴わないキラーT細胞の機能分化のメカニズムPrincipal Investigator

    • Principal Investigator
      横須賀 忠
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Immunology
    • Research Institution
      The Institute of Physical and Chemical Research
      Chiba University

All 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 Other

All Journal Article Presentation Book Patent

  • [Book] 標準免疫学第4版2021

    • Author(s)
      横須賀忠
    • Total Pages
      12
    • Publisher
      医学書院
    • Data Source
      KAKENHI-INTERNATIONAL-16K21731
  • [Book] 標準免疫学第4版2021

    • Author(s)
      横須賀忠
    • Total Pages
      416
    • Publisher
      医学書院
    • ISBN
      9784758103909
    • Data Source
      KAKENHI-PROJECT-19K22545
  • [Book] 「膜タンパク質工学ハンドブック」 第7章 第2節 免疫チェックポイント受容体PD-1とCTLA-42020

    • Author(s)
      横須賀忠、若松英、町山裕亮
    • Total Pages
      624
    • Publisher
      株NTS
    • ISBN
    • Data Source
      KAKENHI-PLANNED-16H06501
  • [Book] 「膜タンパク質工学ハンドブック」 第7章 第2節 免疫チェックポイント受容体PD-1とCTLA-42020

    • Author(s)
      横須賀忠、若松英、町山裕亮
    • Total Pages
      624
    • Publisher
      株NTS
    • ISBN
    • Data Source
      KAKENHI-PROJECT-19K22545
  • [Book] 実験医学増刊号「新規の創薬モダリティ 細胞医薬」2020

    • Author(s)
      横須賀忠, 若松英, 西嶋仁, 竹原朋宏, 西航, 塚本昌子, 町山裕亮
    • Total Pages
      241
    • Publisher
      羊土社
    • ISBN
      9784260042383
    • Data Source
      KAKENHI-PROJECT-19K22545
  • [Book] 「膜タンパク質工学ハンドブック」 第7章 第2節 免疫チェックポイント受容体PD-1とCTLA-42020

    • Author(s)
      横須賀忠、若松英、町山裕亮
    • Total Pages
      624
    • Publisher
      株NTS
    • ISBN
      9784860435370
    • Data Source
      KAKENHI-PROJECT-17H03600
  • [Book] 「膜タンパク質工学ハンドブック」 第7章 第2節 免疫チェックポイント受容体PD-1とCTLA-42019

    • Author(s)
      横須賀忠、若松英、町山裕亮
    • Total Pages
      624
    • Publisher
      (株)NTS
    • Data Source
      KAKENHI-ORGANIZER-16H06495
  • [Book] 実験医学増刊号「新・腫瘍免疫学」免疫チェックポイント分子の分子作用機序2019

    • Author(s)
      横須賀忠、若松英、秦喜久美、竹原朋宏、西航、矢那瀬紀子、町山裕亮
    • Total Pages
      268
    • Publisher
      羊土社
    • ISBN
      9784758103817
    • Data Source
      KAKENHI-PROJECT-17H03600
  • [Book] 実験医学増刊号「新・腫瘍免疫学」免疫チェックポイント分子の分子作用機序2019

    • Author(s)
      横須賀忠、若松英、秦喜久美、竹原朋宏、西航、矢那瀬紀子、町山裕亮
    • Total Pages
      268
    • Publisher
      羊土社
    • ISBN
      9784758103817
    • Data Source
      KAKENHI-PROJECT-19K22545
  • [Book] 「膜タンパク質工学ハンドブック」 第7章 第2節 免疫チェックポイント受容体PD-1とCTLA-42019

    • Author(s)
      横須賀忠、若松英、町山裕亮
    • Total Pages
      624
    • Publisher
      (株)NTS
    • Data Source
      KAKENHI-INTERNATIONAL-16K21731
  • [Book] 実験医学増刊号「新・腫瘍免疫学」免疫チェックポイント分子の分子作用機序2019

    • Author(s)
      横須賀忠、若松英、秦喜久美、竹原朋宏、西航、矢那瀬紀子、町山裕亮
    • Total Pages
      268
    • Publisher
      羊土社
    • Data Source
      KAKENHI-INTERNATIONAL-16K21731
  • [Book] Janeway's免疫生物学原著第9版 第7章リンパ球レセプターシグナル2019

    • Author(s)
      横須賀忠、監訳:笹月健彦、吉開泰信
    • Total Pages
      884
    • Publisher
      南江堂
    • ISBN
      9784524251155
    • Data Source
      KAKENHI-PROJECT-17H03600
  • [Book] Janeway's免疫生物学原著第9版 第7章リンパ球レセプターシグナル2019

    • Author(s)
      横須賀忠、西川博嘉
    • Total Pages
      884
    • Publisher
      南江堂
    • Data Source
      KAKENHI-ORGANIZER-16H06495
  • [Book] Janeway's免疫生物学原著第9版 第7章リンパ球レセプターシグナル2019

    • Author(s)
      横須賀忠、監訳:笹月健彦、吉開泰信
    • Total Pages
      884
    • Publisher
      南江堂
    • ISBN
      9784524251155
    • Data Source
      KAKENHI-PLANNED-16H06501
  • [Book] 実験医学増刊号「新・腫瘍免疫学」免疫チェックポイント分子の分子作用機序2019

    • Author(s)
      横須賀忠、若松英、秦喜久美、竹原朋宏、西航、矢那瀬紀子、町山裕亮
    • Total Pages
      268
    • Publisher
      羊土社
    • ISBN
      9784758103817
    • Data Source
      KAKENHI-PLANNED-16H06501
  • [Book] Janeway's免疫生物学原著第9版 第7章リンパ球レセプターシグナル2019

    • Author(s)
      横須賀忠、西川博嘉
    • Total Pages
      884
    • Publisher
      南江堂
    • Data Source
      KAKENHI-INTERNATIONAL-16K21731
  • [Book] 実験医学増刊号「新・腫瘍免疫学」免疫チェックポイント分子の分子作用機序2019

    • Author(s)
      横須賀忠、若松英、秦喜久美、竹原朋宏、西航、矢那瀬紀子、町山裕亮
    • Total Pages
      268
    • Publisher
      羊土社
    • Data Source
      KAKENHI-ORGANIZER-16H06495
  • [Book] 実験医学 すべてはここから始まった、CTLA-42018

    • Author(s)
      横須賀忠、若松英、古畑昌枝、豊田博子、秦喜久美、矢那瀬紀子、町山裕亮
    • Total Pages
      138
    • Publisher
      羊土社
    • ISBN
    • Data Source
      KAKENHI-PROJECT-17H03600
  • [Book] 東邦医学会雑誌 分子イメージングが拓く免疫チェックポイント受容体のT細胞活性化制御機構2018

    • Author(s)
      横須賀忠、若松英、秦喜久美、矢那瀬紀子、竹原朋宏、町山裕亮
    • Total Pages
      22
    • Publisher
      東邦医学会雑誌編集事務局
    • ISBN
    • Data Source
      KAKENHI-PLANNED-16H06501
  • [Book] 東邦医学会雑誌 分子イメージングが拓く免疫チェックポイント受容体のT細胞活性化制御機構2018

    • Author(s)
      横須賀忠、若松英、秦喜久美、矢那瀬紀子、竹原朋宏、町山裕亮
    • Total Pages
      22
    • Publisher
      東邦医学会雑誌編集事務局
    • ISBN
    • Data Source
      KAKENHI-PROJECT-17H03600
  • [Book] 臨床免疫・アレルギー科 分子イメージングから考察した免疫チェックポイント分子のT細胞抑制機構2018

    • Author(s)
      横須賀忠、若松英、古畑昌枝、豊田博子、秦喜久美、矢那瀬紀子、町山裕亮
    • Total Pages
      119
    • Publisher
      科学評論社
    • ISBN
    • Data Source
      KAKENHI-PROJECT-17H03600
  • [Book] 生物物理2018

    • Author(s)
      横須賀忠、若松英、矢那瀬紀子、秦喜久美、町山裕亮
    • Total Pages
      64
    • Publisher
      日本生物物理学会
    • ISBN
    • Data Source
      KAKENHI-PLANNED-16H06501
  • [Book] アバスーリックマンーピレ分子細胞免疫学原著歳9版 第7章免疫受容体とシグナル伝達2018

    • Author(s)
      横須賀忠、監訳:中尾篤人
    • Total Pages
      577
    • Publisher
      エルゼビア・ジャパン
    • ISBN
      9784860349172
    • Data Source
      KAKENHI-PLANNED-16H06501
  • [Book] アバスーリックマンーピレ分子細胞免疫学原著歳9版 第7章免疫受容体とシグナル伝達2018

    • Author(s)
      横須賀忠、監訳:中尾篤人
    • Total Pages
      577
    • Publisher
      エルゼビア・ジャパン
    • ISBN
      9784860349172
    • Data Source
      KAKENHI-PROJECT-17H03600
  • [Book] 実験医学 すべてはここから始まった、CTLA-42018

    • Author(s)
      横須賀忠、若松英、古畑昌枝、豊田博子、秦喜久美、矢那瀬紀子、町山裕亮
    • Total Pages
      138
    • Publisher
      羊土社
    • ISBN
    • Data Source
      KAKENHI-PLANNED-16H06501
  • [Book] 臨床免疫・アレルギー科 分子イメージングから考察した免疫チェックポイント分子のT細胞抑制機構2018

    • Author(s)
      横須賀忠、若松英、古畑昌枝、豊田博子、秦喜久美、矢那瀬紀子、町山裕亮
    • Total Pages
      119
    • Publisher
      科学評論社
    • ISBN
    • Data Source
      KAKENHI-PLANNED-16H06501
  • [Book] 生物物理2018

    • Author(s)
      横須賀忠、若松英、矢那瀬紀子、秦喜久美、町山裕亮
    • Total Pages
      64
    • Publisher
      日本生物物理学会
    • ISBN
    • Data Source
      KAKENHI-PROJECT-17H03600
  • [Book] 臨床免疫・アレルギー科 細胞膜脂質成分によるT細胞シグナルソームと活性化の制御機構2017

    • Author(s)
      横須賀忠、古畑昌枝、豊田博子、秦喜久美、矢那瀬紀子、町山裕亮
    • Total Pages
      102
    • Publisher
      科学評論社
    • Data Source
      KAKENHI-PLANNED-16H06501
  • [Book] 臨床免疫・アレルギー科 最先端イメージング技術によるTCRシグナル研究の進歩2016

    • Author(s)
      横須賀忠、古畑昌枝、豊田博子、秦喜久美、矢那瀬紀子、町山裕亮
    • Total Pages
      104
    • Publisher
      科学評論社
    • Data Source
      KAKENHI-PLANNED-16H06501
  • [Book] CTLA-4によるT細胞活性化制御の分子機序,臨床免疫・アレルギー科2012

    • Author(s)
      横須賀忠
    • Data Source
      KAKENHI-PROJECT-21590548
  • [Book] 免疫の辞典2011

    • Author(s)
      横須賀忠
    • Publisher
      朝倉書店
    • Data Source
      KAKENHI-PUBLICLY-23113521
  • [Book] 免疫の辞典2011

    • Author(s)
      横須賀忠
    • Publisher
      朝倉書店
    • Data Source
      KAKENHI-PROJECT-21590548
  • [Book] Curr.Top.Microbiol.Immunol. (T. Saito and F. D. Batista (eds.), The immunological synapse, TCR microclusters, and T cell activation.)2010

    • Author(s)
      Yokosuka T, Saito T.
    • Publisher
      Springer-Verlag
    • Data Source
      KAKENHI-PROJECT-19109005
  • [Book] T細胞の活性化に対する補助刺激受容体CTLA-4による時空間的な制御機構の解明2010

    • Author(s)
      横須賀忠、斉藤隆
    • Publisher
      ライフサイエンス新着論文レビュー
    • Data Source
      KAKENHI-PROJECT-21590548
  • [Book] The immunological synapse, TCR microclusters, and T cell activation2010

    • Author(s)
      Yokosuka T and Saito T.
    • Publisher
      Springer-Verlag Berlin Heidelberg
    • Data Source
      KAKENHI-PROJECT-19109005
  • [Book] The immunological synapse, TCR microclusters, and T cell activation2010

    • Author(s)
      Yokosuka T, Saito T.
    • Publisher
      Springer-Verlag Berlin Heidelberg
    • Data Source
      KAKENHI-PROJECT-21590548
  • [Book] T細胞活性化時のTCRとシグナル伝達分子の動態:臨床免疫・アレルギー科50巻3号 2008年9月号2008

    • Author(s)
      横須賀忠
    • Publisher
      科学評論社
    • Data Source
      KAKENHI-PROJECT-19590504
  • [Book] T細胞受容体マイクロクラスター-T細胞活性化を制御するシグナルソームの発見-:感染炎症免疫37巻2号2007

    • Author(s)
      横須賀忠
    • Publisher
      医薬の門社
    • Data Source
      KAKENHI-PROJECT-19590504
  • [Book] 免疫シナプスを構成するTCRマイクロクラスターと T 細胞活性化機構:Annual Review 2008 2007年11月20日2007

    • Author(s)
      横須賀忠
    • Publisher
      中外医学社
    • Data Source
      KAKENHI-PROJECT-19590504
  • [Book] 実験医学2006

    • Author(s)
      横須賀 忠
    • Total Pages
      3
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PROJECT-17790330
  • [Book] シグナル伝達病を知るーその分子機序解明から新たな治療戦略までー(遺伝子医学MOOK6)2006

    • Author(s)
      横須賀 忠
    • Total Pages
      328
    • Publisher
      メディカルドゥ
    • Data Source
      KAKENHI-PROJECT-17790330
  • [Journal Article] PD-L2 suppresses T cell signaling via coinhibitory microcluster formation and SHP2 phosphatase recruitment2021

    • Author(s)
      Tomohiro Takehara, Ei Wakamatsu, Hiroaki Machiyama, Wataru Nishi, Katsura Emoto, Miyuki Azuma, Kenzo Soejima, Koichi Fukunaga, Tadashi Yokosuka
    • Journal Title

      Communications Biology

      Volume: 4 Pages: 1-12

    • DOI

      10.1038/s42003-021-02111-3

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K22545, KAKENHI-PROJECT-20J10564
  • [Journal Article] 受容体シグナルの「デザイン」を評価するイメージング技術~脂質二重支持膜~2020

    • Author(s)
      横須賀忠,若松英,西嶋仁,竹原朋宏,西航,塚本昌子,町山裕亮
    • Journal Title

      実験医学増刊号「新規の創薬モダリティ 細胞医薬」

      Volume: 1 Pages: 64-70

    • Data Source
      KAKENHI-INTERNATIONAL-16K21731
  • [Journal Article] Inhibition of T cell activation and function by the adaptor protein CIN852019

    • Author(s)
      Kong Mei S*., Hashimoto-Tane A*., Kawashima Y., Sakuma M., Yokosuka T., Kometani K., Onishi R., Carpino N., Ohara O., Kurosaki T., Phua K.K. and Saito, T.
    • Journal Title

      Sci Signal

      Volume: 12 Pages: 1609-1625

    • DOI

      10.1126/scisignal.aav4373

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19576, KAKENHI-PROJECT-18K19447, KAKENHI-INTERNATIONAL-16K21731, KAKENHI-ORGANIZER-16H06495, KAKENHI-PLANNED-16H06501, KAKENHI-PUBLICLY-17H05806, KAKENHI-PROJECT-26221306, KAKENHI-PROJECT-17H03600, KAKENHI-PROJECT-16K08851, KAKENHI-PROJECT-18H02672
  • [Journal Article] 細胞膜脂質成分によるT細胞シグナルソームと活性化の制御機構2017

    • Author(s)
      横須賀忠、古畑昌枝、豊田博子、秦喜久美、矢那瀬紀子、町山裕亮
    • Journal Title

      臨床免疫・アレルギー科

      Volume: 67 Pages: 321-326

    • NAID

      40021132650

    • Data Source
      KAKENHI-ORGANIZER-16H06495
  • [Journal Article] Analyzing the Dynamics of Signaling Microclusters2017

    • Author(s)
      Hashimoto-Tane A, Yokosuka T, Saito T.
    • Journal Title

      Methods Mol. Biol.

      Volume: 1584 Pages: 5-64

    • DOI

      10.1007/978-1-4939-6881-7_4

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06501, KAKENHI-PROJECT-16K08851, KAKENHI-PROJECT-17K19576, KAKENHI-INTERNATIONAL-16K21731, KAKENHI-PROJECT-24229004, KAKENHI-ORGANIZER-16H06495, KAKENHI-PUBLICLY-17H05806
  • [Journal Article] 細胞膜脂質成分によるT細胞シグナルソームと活性化の制御機構2017

    • Author(s)
      横須賀忠、古畑昌枝、豊田博子、秦喜久美、矢那瀬紀子、町山裕亮
    • Journal Title

      臨床免疫・アレルギー科

      Volume: 67 Pages: 321-326

    • NAID

      40021132650

    • Data Source
      KAKENHI-INTERNATIONAL-16K21731
  • [Journal Article] Role of interleukin-25 in development of spontaneous arthritis in interleukin-1 receptor antagonist-deficient mice2017

    • Author(s)
      Abe Yasuharu、Nambu Aya、Yamaguchi Sachiko、Takamori Ayako、Suto Hajime、Hirose Sachiko、 Yokosuka Tadashi、Nakae Susumu、Sudo Katsuko
    • Journal Title

      Biochemistry and Biophysics Reports

      Volume: 12 Pages: 62065-62065

    • DOI

      10.1016/j.bbrep.2017.08.006

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-16H06501, KAKENHI-PROJECT-17H03600
  • [Journal Article] Blockage of Core Fucosylation Reduces Cell-Surface Expression of PD-1 and Promotes Anti-tumor Immune Responses of T Cells2017

    • Author(s)
      Okada M, Chikuma S et al.
    • Journal Title

      Cell Rep

      Volume: 20 Pages: 1017-1028

    • DOI

      10.1016/j.celrep.2017.07.027

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K08847, KAKENHI-PROJECT-17K15451, KAKENHI-INTERNATIONAL-16K21731, KAKENHI-ORGANIZER-16H06495, KAKENHI-PLANNED-16H06501, KAKENHI-PUBLICLY-17H05801, KAKENHI-PROJECT-17H03600, KAKENHI-PROJECT-17H07088, KAKENHI-PROJECT-15J07566, KAKENHI-PROJECT-15K19128
  • [Journal Article] Micro-adhesion rings surrounding TCR microclusters are essential for T cell activation.2016

    • Author(s)
      Akiko Hashimoto-Tane, Machie Sakuma, Hiroshi Ike, Tadashi Yokosuka, Yayoi Kimura, Osamu Ohara, Takashi Saito
    • Journal Title

      Journal of Experimental Medicine

      Volume: 213 Pages: 1609-1625

    • DOI

      10.1007/978-3-642-03858-7_5

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-15H01194
  • [Journal Article] 最先端イメージング技術によるTCRシグナル研究の進歩2016

    • Author(s)
      横須賀忠、古畑昌枝、豊田博子、畑喜久美、矢那瀬紀子、町山裕亮
    • Journal Title

      臨床免疫・アレルギー

      Volume: 66 Pages: 169-176

    • NAID

      40020941348

    • Data Source
      KAKENHI-PUBLICLY-15H01194
  • [Journal Article] Micro-adhesion rings surrounding TCR microclusters are essential for T cell activation.2016

    • Author(s)
      Hashimoto-Tane A, Sakuma M, Ike H, Yokosuka T, Kimura Y, Ohara O, Saito T.
    • Journal Title

      The Journal of Experimental Medicine

      Volume: 213 Pages: 1609-1625

    • DOI

      10.1084/jem.20151088

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-ORGANIZER-16H06495, KAKENHI-PLANNED-16H06501, KAKENHI-PROJECT-16K08851, KAKENHI-INTERNATIONAL-16K21731, KAKENHI-PROJECT-16H05230
  • [Journal Article] 最先端イメージング技術によるTCRシグナル研究の進歩2016

    • Author(s)
      横須賀忠、古畑昌枝、豊田博子、秦喜久美、矢那瀬紀子、町山裕亮
    • Journal Title

      臨床免疫・アレルギー科

      Volume: 66 Pages: 169-176

    • NAID

      40020941348

    • Data Source
      KAKENHI-INTERNATIONAL-16K21731
  • [Journal Article] The Multifaceted Role of PD-1 in Health and Disease.2016

    • Author(s)
      Badr MEISG, Hata K, Furuhata M, Toyoda H, Yokosuka T.
    • Journal Title

      Chronic inflammation

      Volume: 1 Pages: 441-457

    • DOI

      10.1007/978-4-431-56068-5_34

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-ORGANIZER-16H06495, KAKENHI-PLANNED-16H06501, KAKENHI-PROJECT-16K08746, KAKENHI-INTERNATIONAL-16K21731
  • [Journal Article] Differential Regulation of T-dependent and -independent Antibody Responses through Arginine Methyltransferase PRMT1 in vivo2016

    • Author(s)
      Kikumi Hata, Noriko Yanase, Katsuko Sudo, Hiroshi Kiyonari, Yoshiko Mukumoto, Junichiro Mizuguchi, Tadashi Yokosuka
    • Journal Title

      FEBS Letters

      Volume: 590 Pages: 1200-1210

    • DOI

      10.1002/1873-3468.12161

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-15H01194, KAKENHI-PROJECT-24590286, KAKENHI-PROJECT-24590590
  • [Journal Article] 最先端イメージング技術によるTCRシグナル研究の進歩2016

    • Author(s)
      横須賀忠、古畑昌枝、豊田博子、秦喜久美、矢那瀬紀子、町山裕亮
    • Journal Title

      臨床免疫・アレルギー科

      Volume: 66 Pages: 169-176

    • NAID

      40020941348

    • Data Source
      KAKENHI-ORGANIZER-16H06495
  • [Journal Article] T細胞免疫シナプス研究の最新事情2015

    • Author(s)
      横須賀忠
    • Journal Title

      臨床免疫・アレルギー

      Volume: 63 Pages: 193-200

    • NAID

      40020362893

    • Data Source
      KAKENHI-PUBLICLY-25113725
  • [Journal Article] 免疫シナプス2015

    • Author(s)
      横須賀忠
    • Journal Title

      生体の科学

      Volume: 66 Pages: 522-523

    • Data Source
      KAKENHI-PUBLICLY-15H01194
  • [Journal Article] 免疫シナプス2015

    • Author(s)
      横須賀忠
    • Journal Title

      生体の科学

      Volume: 66 Pages: 522-523

    • Data Source
      KAKENHI-PROJECT-24590590
  • [Journal Article] T細胞免疫シナプス研究の最新事情2015

    • Author(s)
      横須賀忠
    • Journal Title

      臨床免疫・アレルギー科

      Volume: 63 Pages: 193-200

    • NAID

      40020362893

    • Data Source
      KAKENHI-PUBLICLY-15H01194
  • [Journal Article] T細胞活性化におけるチェックポイント2015

    • Author(s)
      横須賀忠
    • Journal Title

      炎症と免疫

      Volume: 23 Pages: 10-20

    • Data Source
      KAKENHI-PUBLICLY-15H01194
  • [Journal Article] T細胞免疫シナプス研究の最新事情2015

    • Author(s)
      横須賀忠
    • Journal Title

      臨床免疫・アレルギー科

      Volume: 63 Pages: 193-200

    • NAID

      40020362893

    • Data Source
      KAKENHI-PROJECT-24590590
  • [Journal Article] Clustering of CARMA1 through SH3-GUK domain interactions is required for its activation of NF-κB signaling2015

    • Author(s)
      Hara, H., Yokosuka, T., Hirakawa, H., Ishihara, C., Yasukawa, S., Yamazaki, M., Koseki, H., Yoshida, H. and Saito, T.
    • Journal Title

      Nat Commun

      Volume: 6 Pages: 5555-5555

    • DOI

      10.1038/ncomms6555

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24229004, KAKENHI-PROJECT-24390256, KAKENHI-PROJECT-24590590, KAKENHI-PUBLICLY-25113725, KAKENHI-PROJECT-25460594
  • [Journal Article] T細胞におけるPD-1の生理機能と分子基盤2014

    • Author(s)
      横須賀忠
    • Journal Title

      腫瘍内科

      Volume: 14 Pages: 419-426

    • Data Source
      KAKENHI-PUBLICLY-25113725
  • [Journal Article] T細胞活性化におけるチェックポイント2014

    • Author(s)
      横須賀忠
    • Journal Title

      炎症と免疫

      Volume: 23 Pages: 10-20

    • Data Source
      KAKENHI-PUBLICLY-25113725
  • [Journal Article] Protein kinase C-η controls CTLA-4-mediated regulatory T cell function2014

    • Author(s)
      Kong, K-F., Yokosuka, T., Canonigo-Balancio, A.J., et al
    • Journal Title

      Nature Immunology

      Volume: 12 Pages: 1105-1112

    • DOI

      10.1038/ni.2120

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19059013, KAKENHI-PROJECT-19109005, KAKENHI-PROJECT-21590548, KAKENHI-PUBLICLY-23113521, KAKENHI-PROJECT-24590590, KAKENHI-PUBLICLY-25113725
  • [Journal Article] T細胞におけるPD-1の生理機能と分子基盤2014

    • Author(s)
      横須賀忠
    • Journal Title

      腫瘍内科

      Volume: 14 Pages: 419-426

    • Data Source
      KAKENHI-PROJECT-24590590
  • [Journal Article] T細胞活性化におけるチェックポイント2014

    • Author(s)
      横須賀忠
    • Journal Title

      炎症と免疫

      Volume: 23 Pages: 10-20

    • Data Source
      KAKENHI-PROJECT-24590590
  • [Journal Article] リンパ球に特異的なアクチン脱キャッピングタンパク質RltprはCD28を介するT細胞の活性化と制御性T細胞の分化に必須である2013

    • Author(s)
      横須賀忠、斉藤隆、Bernard Malissen
    • Journal Title

      ライフサイエンス新着論文レビュー

      Volume: -

    • Data Source
      KAKENHI-PUBLICLY-25113725
  • [Journal Article] The lymphoid lineage-specific actin-uncapping protein Rltpr is essential for costimulation via CD28 and the development of regulatory T cells2013

    • Author(s)
      Liang, Y., Cucchetti, M., Roncagalli, R., Yokosuka, T., Malzac, A., Bertosio, E., Imbert, J., Nijman, I.J., Suchanek, M., Saito, T., Wulfing, C., Malissen, B., Malissen, M.
    • Journal Title

      Nature Immunology

      Volume: 14 Pages: 858-866

    • DOI

      10.1038/ni.2634

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24229004, KAKENHI-PROJECT-24590590, KAKENHI-PUBLICLY-25113725
  • [Journal Article] リンパ球に特異的なアクチン脱キャッピングタンパク質RltprはCD28を介するT細胞の活性化と制御性T細胞の分化に必須である2013

    • Author(s)
      横須賀忠、斉藤隆、Bernard Malissen
    • Journal Title

      ライフサイエンス新着論文レビュー

      Volume: -

    • Data Source
      KAKENHI-PROJECT-24590590
  • [Journal Article] Programmed cell death 1 forms negative costimulatory microclusters that directly inhibit T cell receptor signaling by recruiting phosphatase SHP22012

    • Author(s)
      Yokosuka T, Takamatsu M, Kobayashi-Imanishi W, Hashimoto-Tani A, Azuma M, Saito T
    • Journal Title

      Journal of Experimental Medicine

      Volume: 209 Pages: 1201-1217

    • DOI

      10.1084/jem.20112741

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23249082, KAKENHI-PROJECT-24229004, KAKENHI-PROJECT-24590590, KAKENHI-PROJECT-24590591, KAKENHI-PUBLICLY-23113521
  • [Journal Article] CIN85 regulates the canonical NF-κB pathway and subsequent B cell responses2011

    • Author(s)
      Kometani K, Yamada T, Sasaki Y, Yokosuka T, Saito T, Rajewsky K, Ishiai M, Hikida M, Kurosaki T.
    • Journal Title

      J Exp Med

      Volume: 208(7) Pages: 1447-1457

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590548
  • [Journal Article] Dynein-driven transport of T cell receptor microclusters regulates immune synapse formation and T cell activation2011

    • Author(s)
      Hashimoto-Tane A, Yokosuka T, Sakata-Sogawa K, Sakuma M, Ishihara C, Tokunaga M, Saito T.
    • Journal Title

      Immunity

      Volume: 34(6) Pages: 919-931

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590548
  • [Journal Article] Dynein-driven transport of T cell receptor microclusters regulates immune synapse formation and T cell activation2011

    • Author(s)
      Hashimoto-Tane A, Yokosuka T, Sakata-Sogawa K, Sakuma M, Ishihara C, Tokunaga M, Saito T.
    • Journal Title

      Immunity

      Volume: 34 Pages: 919-931

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19109005
  • [Journal Article] A motif in the V3 domain of the kinase PKC-θdetermines its localization in the immunological synapse and functions in T cells via association with CD282011

    • Author(s)
      Kong K-F, Yokosuka T, Canonigo-Balancio A. J, Isakov N, Saito T, Altman A.
    • Journal Title

      Nat. Immunol

      Volume: 12(11) Pages: 1105-12

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590548
  • [Journal Article] CIN85 regulates the canonical NF-κB pathway and subsequent B cell responses2011

    • Author(s)
      Kometani K, Yamada T, Sasaki Y, Yokosuka T, Saito T, Rajewsky K, Ishiai M, Hikida M, Kurosaki T.
    • Journal Title

      J. Exp. Med

      Volume: 208 Pages: 1447-1457

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19109005
  • [Journal Article] Spatiotemporal basis of CTLA-4 costimulatory molecule-mediated negative regulation of T cell activation2010

    • Author(s)
      Yokosuka T, Kobayashi W, Takamatsu M, Sakata-Sogawa K, Zeng H, Hashimoto-Tane A, Yagita H, Tokunaga M, Saito T
    • Journal Title

      Immunity

      Volume: 33 Pages: 326-339

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19109005
  • [Journal Article] Spatiotemporal basis of CTLA-4 costimulatory molecule-mediated negative regulation of T cell activation.2010

    • Author(s)
      Tadashi Yokosuka
    • Journal Title

      Immunity

      Volume: 33 Pages: 326-339

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19109005
  • [Journal Article] T cell receptor-microclusters critical for T-cell activation are formed independently of lipid raft clustering2010

    • Author(s)
      Hashimoto-Tane A, Yokosuka T, Ishihara C, Sakuma M, Kobayashi W and Saito T.
    • Journal Title

      Mol. Cel. Biol

      Volume: 30 Pages: 3421-3429

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19109005
  • [Journal Article] Dynamic regulation of T cell activation and co-stimulation through TCR-microclusters2010

    • Author(s)
      Saito T, Yokosuka T, Hashimoto-Tane A.
    • Journal Title

      FEBS Lett

      Volume: 584 Pages: 4865-4871

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19109005
  • [Journal Article]2010

    • Author(s)
      Tadashi Yokosuka
    • Journal Title

      Immunological Synapse (Current Topics in Microbiology and Immunology)(Springer-Verlag Berlin Heidelberg)

      Pages: 81-107

    • Data Source
      KAKENHI-PROJECT-19109005
  • [Journal Article]2010

    • Author(s)
      Tadashi Yokosuka
    • Journal Title

      Immunological Synapse(Current Topics in Microbiology and Immunology)(Springer-Verlag Berlin Heidelberg)

      Pages: 81-107

    • Data Source
      KAKENHI-PROJECT-21590548
  • [Journal Article] Spatiotemporal basis of CTLA-4 costimulatory molecule-mediated negative regulation of T cell activation2010

    • Author(s)
      Tadashi Yokosuka
    • Journal Title

      Immunity

      Volume: 33 Pages: 326-339

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590548
  • [Journal Article] T cell receptor-microclusters critical for T-cell activation are formed independently of lipid raft clustering2010

    • Author(s)
      Hashimoto-Tane A, Yokosuka T, Ishihara C, Sakuma M, Kobayashi W, Saito T.
    • Journal Title

      Mol Cel Biol

      Volume: 30(14) Pages: 3421-3429

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590548
  • [Journal Article] Dynamic regulation of T cell activation and co-stimulation through TCR-microclusters2010

    • Author(s)
      Saito T, Yokosuka T, Hashimoto-Tane A.
    • Journal Title

      FEBS Lett

      Volume: 584 Pages: 4865-4871

    • Data Source
      KAKENHI-PROJECT-21590548
  • [Journal Article] Spatiotemporal basis of CTLA-4 costimulatory molecule-mediated negative regulation of T cell activation2010

    • Author(s)
      Yokosuka T, Kobayashi W, Takamatsu M, Sakata-Sogaw, K, Zen H, Hashimoto-Tane A, Yagita H, Tokunaga M, Saito T.
    • Journal Title

      Immunity

      Volume: 33(3) Pages: 326-339

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590548
  • [Journal Article] Dynamic regulation of T-cell costimulation through TCR?CD28 microclusters2009

    • Author(s)
      Yokosuka T. and Saito T.
    • Journal Title

      Immunol. Rev. 229

      Pages: 27-40

    • Data Source
      KAKENHI-PROJECT-19590504
  • [Journal Article] Dynamic regulation of T-cell costimulation through TCR-CD28 microclusters2009

    • Author(s)
      Tadashi Yokosuka
    • Journal Title

      Immnological Review 299

      Pages: 27-40

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590548
  • [Journal Article] CRTAM confers late-stage activation of CD8+T cells to regulate retention within lymph node2009

    • Author(s)
      Takeuchi A, Itoh Y, Takumi A, Ishihara C, Arase N, Yokosuka T, Koseki H, Yamasaki S, Takai Y, Miyoshi J, Ogasawara K, and Saito T.
    • Journal Title

      J. Immunol

      Volume: 183 Pages: 4220-4228

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19109005
  • [Journal Article] Dynamic regulation of T-cell costimulation through TCR-CD28 microclusters2009

    • Author(s)
      Tadashi Yokosuka
    • Journal Title

      Immunological Reviews 229

      Pages: 27-40

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19109005
  • [Journal Article] Dynamic regulation of T-cell costimulation through TCR-CD28 microclusters2009

    • Author(s)
      Yokosuka T and Saito T
    • Journal Title

      Immunol. Rev

      Volume: 229 Pages: 27-40

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19109005
  • [Journal Article] Costimulation signals mediated by CD28-microclusters2009

    • Author(s)
      Yokosuka, T., Saito, T.
    • Journal Title

      Immunol.Rev. 229

      Pages: 27-40

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19109005
  • [Journal Article] Dynamic regulation of T-cell costimulation through TCR-CD28 microclusters2009

    • Author(s)
      Yokosuka T, Saito T.
    • Journal Title

      Immunol Rev

      Volume: 229(1) Pages: 27-40

    • Data Source
      KAKENHI-PROJECT-21590548
  • [Journal Article] CRTAM confers late-stage activation of CD8+T cells to regulate retention within lymph node2009

    • Author(s)
      Takeuchi A, Itoh Y, Takumi A, Ishihara C, Arase N, Yokosuka T, Koseki H, Yamasaki S, Takai Y, Miyoshi J, Ogasawara K, Saito T.
    • Journal Title

      J Immunol

      Volume: 183(7) Pages: 4220-4228

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590548
  • [Journal Article] Spatiotemporal regulation of T cell costimulation by TCR-CD28 microclusters and protein kinase C θ translocation2008

    • Author(s)
      Yokosuka, T.
    • Journal Title

      Immunity 29

      Pages: 589-601

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19109005
  • [Journal Article] Spatiotemporal regulation of T cell costimulation by TCR-CD28 microclusters through protein kinase C θ translocation2008

    • Author(s)
      Yokosuka T., Kobayashi, W., Sakata-Sogawa K., Hashimoto-Tane, A., Dustin, M.L., Tokunaga. M., Saito, T.
    • Journal Title

      Immunity 29

      Pages: 589-301

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590504
  • [Journal Article] Spatiotemporal regulation of T cell costimulation by TCR-CD28 microclusters through protein kinase C θ translocation2008

    • Author(s)
      Yokosuka T, Kobayashi W, Sakata-Sogawa K, Takamatsu M, Hashimoto-Tane A, Dustin ML, Tokunaga M, Saito T
    • Journal Title

      Immunity 29

      Pages: 589-601

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19109005
  • [Journal Article] T細胞活性化時のTCRとシグナル伝達分子の動態2008

    • Author(s)
      横須賀忠
    • Journal Title

      臨床免疫・アレルギー科(Clinical Immunology & Allergology) 50

      Pages: 247-254

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590504
  • [Journal Article] LFA-1 decreases the antigen dose for T cell activation in vivo2008

    • Author(s)
      Wang Y, Shibuya K, Yamashita Y, Shirakawa J, Shibata K, Kai H, Yokosuka T, Saito T, Honda S, Tahara-Hanaoka S, Shibuya A.
    • Journal Title

      Int. Immunol. 20

      Pages: 1119-1127

    • NAID

      10022599219

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590504
  • [Journal Article] Spatiotemporal regulation of T cell costimulation by TCR-CD28 microclusters through protein kinase Cθtranslocation2008

    • Author(s)
      Yokosuka T, Kobayashi W, Sakata-Sogawa, K, Takamatsu M, Hashimoto-Tane A, Dustin ML, Tokunaga M, Saito T.
    • Journal Title

      Immunity

      Volume: 29 Pages: 589-601

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19109005
  • [Journal Article] Genetic analysis reveals an intrinsic property of the germinal center B cells to generate A:T mutations2008

    • Author(s)
      Ouchida R, Ukai A, Mori H, Kawamura K, Dolle ME, Tagawa M, Sakamoto A, Tokuhisa T, Yokosuka T, Saito T, Yokoi M, Hanaoka F, Vijg J, Wang JY.
    • Journal Title

      DNA Repair 7

      Pages: 1392-1398

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590504
  • [Journal Article] Spatiotemporal regulation of T cell costimulation by TCR-CD28 microclusters through protein kinase C θ translocation2008

    • Author(s)
      Yokosuka, T.
    • Journal Title

      Immunity 29

      Pages: 589-601

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590504
  • [Journal Article] Cloning of B cell-specific membrane tetraspanning molecule BTS possessing B cell proliferation-inhibitory function2007

    • Author(s)
      Suenaga T, Arase H, Yamasaki S, Kohno M, Yokosuka T, Takeuchi A, Hattori T, Saito T.
    • Journal Title

      Eur. J. Immunol. 37

      Pages: 3197-3207

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590504
  • [Journal Article] 免疫シナプスを構成するTCRマイクロクラスターとT細胞活性化機構2007

    • Author(s)
      横須賀 忠
    • Journal Title

      Annual Review免疫2008

      Pages: 1-11

    • Data Source
      KAKENHI-PROJECT-19590504
  • [Journal Article] Cloning of B cell-specific membrane tetraspanning molecule BTS possessing B cell proliferation-inhibitory function2007

    • Author(s)
      Suenaga T, Arase H, Yamasaki S, Kohno M, Yokosuka T, Takeuchi A, Hattori T, Saito T.
    • Journal Title

      Eur. J. Immunol

      Volume: 37 Pages: 3197-3207

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19109005
  • [Journal Article] T細胞活性化の開始と維持を担うシグナルソーム'TCRマイクロクラスター'2006

    • Author(s)
      横須賀 忠
    • Journal Title

      実験医学 24・4

      Pages: 499-501

    • Data Source
      KAKENHI-PROJECT-17790330
  • [Journal Article] T細胞受容体のクラスター形成とT細胞活性化のシグナル伝達2006

    • Author(s)
      横須賀 忠
    • Journal Title

      臨床免疫・アレルギー科 46

      Pages: 227-232

    • NAID

      40007394147

    • Data Source
      KAKENHI-PROJECT-17790330
  • [Journal Article] Newly generated T cell receptor microclusters initiate and sustain T cell activation by recruitment of Zap70 and SLP-762005

    • Author(s)
      Yokosuka, T
    • Journal Title

      Nat.Immunol. 6・12

      Pages: 1253-1253

    • Data Source
      KAKENHI-PROJECT-17790330
  • [Journal Article] フローサイトメトリー2004

    • Author(s)
      横須賀 忠
    • Journal Title

      蛋白質 核酸 酵素 49

      Pages: 1620-1627

    • Data Source
      KAKENHI-PROJECT-15790247
  • [Journal Article] CD8^+T細胞のエフェクター、メモリーへの分化と細胞増殖2004

    • Author(s)
      横須賀 忠
    • Journal Title

      臨床免疫 42・3

      Pages: 271-277

    • Data Source
      KAKENHI-PROJECT-15790247
  • [Journal Article] Programmed cell death 1 forms negative costimulatory microclusters that directly inhibit T cell receptor signaling by recruiting phosphatase SHP2

    • Author(s)
      Yokosuka T, Takamatsu M, Kobayashi-Imanishi W, Hashimoto-Tane A, Azuma M, Saito T.
    • Journal Title

      J. Exp. Med

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19109005
  • [Patent] クラスターを形成し得る細胞表面レセプターを有する細胞の活性化制御剤およびそのスクリーニング方法2005

    • Inventor(s)
      斉藤 隆, 横須賀 忠
    • Industrial Property Rights Holder
      理化学研究所
    • Industrial Property Number
      2005-298279
    • Filing Date
      2005-10-13
    • Data Source
      KAKENHI-PROJECT-17790330
  • [Presentation] 一分子動態解析法を用いたT細胞活性化におけるシグナルソームの時空間的制御機構の解明~簡単・簡便なキメラ抗原受容体CAR-T細胞療法に向けて~2020

    • Author(s)
      町山裕亮、若松英、矢那瀬紀子、横須賀忠
    • Organizer
      第36回日本DDS学会学術集会
    • Data Source
      KAKENHI-INTERNATIONAL-16K21731
  • [Presentation] Role of cytoskeleton in Chimeric antigen receptor (CAR)-T cell therapy.2020

    • Author(s)
      Machiyama H, Wakamatsu E, Yokosuka T
    • Organizer
      The 43rd Annual Meeting of Molecular Biology Society of Japan
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K22545
  • [Presentation] Visualizing of neo-self phenomena in chimeric antigen receptor (CAR)-T cells.2020

    • Author(s)
      町山裕亮, 若松英, 秦喜久美, 矢那瀬紀子, 竹原朋宏, 西航, Mamonkin Maksim, Brenner Malcolm K, 横須賀忠
    • Organizer
      第58回日本生物物理学会年会
    • Data Source
      KAKENHI-INTERNATIONAL-16K21731
  • [Presentation] Role of cytoskeleton in Chimeric antigen receptor (CAR)-T cell therapy2020

    • Author(s)
      Hiroaki Machiyama, Ei Wakamatsu, Tadashi Yokosuka
    • Organizer
      The 43rd Annual Meeting of Molecular Biology Society of Japan
    • Data Source
      KAKENHI-INTERNATIONAL-16K21731
  • [Presentation] 分子イメージングによるPD-1ーPD-L2を介するT細胞抑制機構の解明2020

    • Author(s)
      竹原朋宏, 若松英, 町山裕亮, 副島研造, 福永興壱, 横須賀忠
    • Organizer
      第24回日本がん免疫学会総会
    • Data Source
      KAKENHI-PROJECT-19K22545
  • [Presentation] Visualizing of neo-self phenomena in chimeric antigen receptor (CAR)-T cells.2020

    • Author(s)
      町山裕亮, 若松英, 秦喜久美, 矢那瀬紀子, 竹原朋宏, 西航, Mamonkin M, Brenner MK, 横須賀忠
    • Organizer
      第58回日本生物物理学会年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K22545
  • [Presentation] 分子イメージングによるPD-1ーPD-L2を介するT細胞抑制機構の解明2020

    • Author(s)
      竹原朋宏、若松英、町山裕亮、副島研造、福永興壱、横須賀忠
    • Organizer
      第24回日本がん免疫学会総会
    • Data Source
      KAKENHI-INTERNATIONAL-16K21731
  • [Presentation] 一分子動態解析法を用いたT細胞活性化におけるシグナルソームの時空間的制御機構の解明~簡単・簡便なキメラ抗原受容体CAR-T細胞療法に向けて~2020

    • Author(s)
      町山裕亮, 若松英, 矢那瀬紀子, 横須賀忠
    • Organizer
      第36回日本DDS学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K22545
  • [Presentation] 分子イメージングが拓くT細胞活性化機構の解明とがん免疫療法2020

    • Author(s)
      横須賀忠
    • Organizer
      第82回日本血液学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K22545
  • [Presentation] 分子イメージングが拓くT細胞活性化機構の解明とがん免疫療法2020

    • Author(s)
      横須賀忠
    • Organizer
      第82回日本血液学会学術集会
    • Data Source
      KAKENHI-INTERNATIONAL-16K21731
  • [Presentation] CARマイクロクラスターによる腫瘍抗原の認識とCAR-T細胞活性化の時空間的制御機構2019

    • Author(s)
      横須賀忠、若松英、矢那瀬紀子、秦喜久美、竹原朋宏、西航、町山裕亮
    • Organizer
      第23回日本がん免疫学会総会
    • Data Source
      KAKENHI-INTERNATIONAL-16K21731
  • [Presentation] Indirect suppression of CD4+ T cell activation by LAG3-mediated trogocytosis of MHC Class II.2019

    • Author(s)
      Wakamatsu E, Machiyama H, Toyota H, Furuhata M, Hata K, Yanase N, Yokosuka T
    • Organizer
      第48回日本免疫学会学術集会
    • Data Source
      KAKENHI-ORGANIZER-16H06495
  • [Presentation] Different requirement of the coreceptors CD4 and CD8 for initiation of T cell activation.2019

    • Author(s)
      Machiyama H Wakamatsu E, Hata K, Yanase N, Furuhata M, Toyota H, Yokosuka T
    • Organizer
      第48回日本免疫学会総会
    • Data Source
      KAKENHI-PROJECT-17H03600
  • [Presentation] Programmed cell death 2 forms coinhibitory microclusters that directly attenuate T cell receptor signaling by recruiting the phosphatase SHP2.2019

    • Author(s)
      Takehara T, Wakamatsu E, Machiyama H, Yanase N, Toyota H, Furuhata M, Koichi F, Soejima K, Yokosuka T
    • Organizer
      第48回日本免疫学会総会
    • Data Source
      KAKENHI-PROJECT-19K22545
  • [Presentation] 分子イメージングが拓くT細胞活性化機構の解明とがん免疫療法2019

    • Author(s)
      横須賀忠
    • Organizer
      第81回日本血液学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H03600
  • [Presentation] Programmed cell death 2 forms coinhibitory microclusters that directly attenuate T cell receptor signaling by recruiting phosphatase SHP22019

    • Author(s)
      Takehara T, Wakamatsu E, Machiyama H, Yanase N, Hata K, Toyoda H, Furuhata M, Yasuda H, Soejima K, Yokosuka T.
    • Organizer
      American Association for Cancer Research
    • Int'l Joint Research
    • Data Source
      KAKENHI-INTERNATIONAL-16K21731
  • [Presentation] Programmed cell death 2 forms coinhibitory microclusters that directly attenuate T cell receptor signaling by recruiting the phosphatase SHP2.2019

    • Author(s)
      Takehara T, Wakamatsu E, Machiyama H, Yanase N, Toyota H, Furuhata M, Koichi F, Soejima K, Yokosuka T
    • Organizer
      第48回日本免疫学会学術集会
    • Data Source
      KAKENHI-ORGANIZER-16H06495
  • [Presentation] CARマイクロクラスターによる腫瘍抗原の認識とCAR-T細胞活性化の時空間的制御機構2019

    • Author(s)
      横須賀忠、若松英、矢那瀬紀子、秦喜久美、竹原朋宏、西航、町山裕亮
    • Organizer
      第23回日本がん免疫学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K22545
  • [Presentation] 多様なT細胞シグナルソームによる腫瘍およびネオ・セルフ抗原認識の分子機構2019

    • Author(s)
      横須賀忠、若松英、矢那瀬紀子、秦喜久美、竹原朋宏、西航、町山裕亮
    • Organizer
      第92回日本生化学会大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K22545
  • [Presentation] 分子イメージングが拓くT細胞活性化機構の解明とがん免疫療法 -免疫チェックポイント分子とキメラ抗原受容体のシグナルソーム-2019

    • Author(s)
      横須賀忠
    • Organizer
      Scientific Exchange Meeting in 北九州2019
    • Invited
    • Data Source
      KAKENHI-PLANNED-16H06501
  • [Presentation] 分子イメージングが拓くがん免疫応答とT細胞活性化メカニズムの解明2019

    • Author(s)
      横須賀忠
    • Organizer
      第75回日本口腔科学会学術集会
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-16H06495
  • [Presentation] 末梢T細胞ではLckと共受容体CD4/CD8との協調的クラスター形成よって初期のTCRシグナルが惹起される2019

    • Author(s)
      町山裕亮、若松英、秦喜久美、矢那瀬紀子、古畑昌枝、豊田博子、横須賀忠
    • Organizer
      Kyot T cell Conference 第29回学術集会
    • Data Source
      KAKENHI-PLANNED-16H06501
  • [Presentation] 分子イメージングが拓くT細胞活性化機構の解明とがん免疫療法~免疫チェックポイント分子とキメラ抗原受容体のシグナルソーム~2019

    • Author(s)
      横須賀忠
    • Organizer
      Scientific Exchange Meeting in 北九州2019
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-16H06495
  • [Presentation] 分子イメージングが拓くT細胞活性化機構の解明とがん免疫療法への応用 -チェックポイント分子のとキメラ抗原受容体CARのシグナルソーム形成-2019

    • Author(s)
      横須賀忠
    • Organizer
      Urology Conference at Shinanomachi
    • Invited
    • Data Source
      KAKENHI-PLANNED-16H06501
  • [Presentation] 多様なT細胞シグナルソームによる腫瘍およびネオ・セルフ抗原認識の分子機構2019

    • Author(s)
      横須賀忠、若松英、矢那瀬紀子、秦喜久美、竹原朋宏、西航、町山裕亮
    • Organizer
      第92回日本生化学会大会
    • Data Source
      KAKENHI-ORGANIZER-16H06495
  • [Presentation] 分子イメージングが拓くT細胞活性化機構の解明とがん免疫応答ーチェックポイント分子とキメラ抗原受容体CARのシグナルソーム形成ー2019

    • Author(s)
      横須賀忠
    • Organizer
      Immuno-Oncology Forum in Ehime
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H03600
  • [Presentation] Programmed cell death 2 forms coinhibitory microclusters that directly attenuate T cell receptor signaling by recruiting the phosphatase SHP2.2019

    • Author(s)
      Takehara T, Wakamatsu E, Machiyama H, Yanase N, Toyota H, Furuhata M, Koichi F, Soejima K, Yokosuka T
    • Organizer
      第48回日本免疫学会学術集会
    • Data Source
      KAKENHI-INTERNATIONAL-16K21731
  • [Presentation] Programmed cell death 2 forms coinhibitory microclusters that directly attenuate T cell receptor signaling by recruiting phosphatase SHP22019

    • Author(s)
      Takehara T, Wakamatsu E, Machiyama H, Yanase N, Hata K, Toyoda H, Furuhata M, Yasuda H, Soejima K, Yokosuka T.
    • Organizer
      American Association fro Cancer Reserach
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06501
  • [Presentation] Indirect suppression of CD4+ T cell activation by LAG3-mediated trogocytosis of MHC Class II.2019

    • Author(s)
      Wakamatsu E, Machiyama H, Toyota H, Furuhata M, Hata K, Yanase N, Yokosuka T
    • Organizer
      第48回日本免疫学会学術集会
    • Data Source
      KAKENHI-INTERNATIONAL-16K21731
  • [Presentation] 分子イメージングが拓くT細胞活性化機構の解明とがん免疫療法への応用 -チェックポイント分子のとキメラ抗原受容体CARのシグナルソーム形成-2019

    • Author(s)
      横須賀忠
    • Organizer
      Urology Conference at Shinanomachi
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K22545
  • [Presentation] Indirect suppression of CD4+ T cell activation by LAG3-mediated trogocytosis of MHC Class II.2019

    • Author(s)
      Wakamatsu E, Machiyama H, Toyota H, Furuhata M, Hata K, Yanase N, Yokosuka T
    • Organizer
      第48回日本免疫学会総会
    • Data Source
      KAKENHI-PROJECT-19K22545
  • [Presentation] CARマイクロクラスターによる腫瘍抗原の認識とCAR-T細胞活性化の時空間的制御機構2019

    • Author(s)
      横須賀忠、若松英、矢那瀬紀子、秦喜久美、竹原朋宏、西航、町山裕亮
    • Organizer
      第23回日本がん免疫学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H03600
  • [Presentation] Indirect suppression of CD4+ T cell activation by LAG3-mediated trogocytosis of MHC Class II.2019

    • Author(s)
      Wakamatsu E, Machiyama H, Toyota H, Furuhata M, Hata K, Yanase N, Yokosuka T
    • Organizer
      第48回日本免疫学会総会
    • Data Source
      KAKENHI-PROJECT-17H03600
  • [Presentation] 分子イメージングが拓くT細胞活性化機構の解明とがん免疫療法への応用 -チェックポイント分子のとキメラ抗原受容体CARのシグナルソーム形成-2019

    • Author(s)
      横須賀忠
    • Organizer
      Urology Conference at Shinanomachi
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H03600
  • [Presentation] 末梢T細胞ではLckと共受容体CD4/CD8との協調的クラスター形成よって初期のTCRシグナルが惹起される2019

    • Author(s)
      町山裕亮、若松英、秦喜久美、矢那瀬紀子、古畑昌枝、豊田博子、横須賀忠
    • Organizer
      Kyot T cell Conference 第29回学術集会
    • Data Source
      KAKENHI-PROJECT-17H03600
  • [Presentation] 多様なT細胞シグナルソームによる腫瘍およびネオ・セルフ抗原認識の分子機構2019

    • Author(s)
      横須賀忠、若松英、矢那瀬紀子、秦喜久美、竹原朋宏、西航、町山裕亮
    • Organizer
      第92回日本生化学会大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H03600
  • [Presentation] Programmed cell death 2 forms coinhibitory microclusters that directly attenuate T cell receptor signaling by recruiting phosphatase SHP22019

    • Author(s)
      Takehara T, Wakamatsu E, Machiyama H, Yanase N, Hata K, Toyoda H, Furuhata M, Yasuda H, Soejima K, Yokosuka T.
    • Organizer
      American Association fro Cancer Reserach
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K22545
  • [Presentation] Programmed cell death 2 forms coinhibitory microclusters that directly attenuate T cell receptor signaling by recruiting the phosphatase SHP2.2019

    • Author(s)
      Takehara T, Wakamatsu E, Machiyama H, Yanase N, Toyota H, Furuhata M, Koichi F, Soejima K, Yokosuka T
    • Organizer
      第48回日本免疫学会総会
    • Data Source
      KAKENHI-PROJECT-17H03600
  • [Presentation] Extrinsic and intrinsic inhibition of T cell response by co-inhibitory receptors, TIGIT and CD96.2019

    • Author(s)
      Yanase N, Machiyama H, Toyota H, Furuhata M, Hata K, Takehara T, Wakamatsu E, Yokosuka T
    • Organizer
      第48回日本免疫学会学術集会
    • Data Source
      KAKENHI-ORGANIZER-16H06495
  • [Presentation] 末梢T細胞ではLckと共受容体CD4/CD8との協調的クラスター形成よって初期のTCRシグナルが惹起される2019

    • Author(s)
      町山裕亮、若松英、秦喜久美、矢那瀬紀子、古畑昌枝、豊田博子、横須賀忠
    • Organizer
      Kyot T cell Conference 第29回学術集会
    • Data Source
      KAKENHI-PROJECT-19K22545
  • [Presentation] Different requirement of the coreceptors CD4 and CD8 for initiation of T cell activation.2019

    • Author(s)
      Machiyama H Wakamatsu E, Hata K, Yanase N, Furuhata M, Toyota H, Yokosuka T
    • Organizer
      第48回日本免疫学会学術集会
    • Data Source
      KAKENHI-INTERNATIONAL-16K21731
  • [Presentation] 分子イメージングが拓くT細胞活性化機構の解明とがん免疫療法 -免疫チェックポイント分子とキメラ抗原受容体のシグナルソーム-2019

    • Author(s)
      横須賀忠
    • Organizer
      Scientific Exchange Meeting in 北九州2019
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H03600
  • [Presentation] 分子イメージングが拓くT細胞活性化機構の解明とがん免疫療法2019

    • Author(s)
      横須賀忠
    • Organizer
      第81回日本血液学会学術集会
    • Invited
    • Data Source
      KAKENHI-PLANNED-16H06501
  • [Presentation] 分子イメージングが拓くT細胞活性化機構の解明とがん免疫療法ー免疫チェックポイント分子とキメラ抗原受容体のシグナルソーム2019

    • Author(s)
      横須賀忠
    • Organizer
      Scientific Exchange Meeting in 北九州2019
    • Data Source
      KAKENHI-INTERNATIONAL-16K21731
  • [Presentation] CARマイクロクラスターによる腫瘍抗原の認識とCAR-T細胞活性化の時空間的制御機構2019

    • Author(s)
      横須賀忠、若松英、矢那瀬紀子、秦喜久美、竹原朋宏、西航、町山裕亮
    • Organizer
      第23回日本がん免疫学会総会
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-16H06495
  • [Presentation] 分子イメージングが拓くT細胞活性化機構の解明とがん免疫応答ーチェックポイント分子とキメラ抗原受容体CARのシグナルソーム形成ー2019

    • Author(s)
      横須賀忠
    • Organizer
      Immuno-Oncology Forum in Ehime
    • Invited
    • Data Source
      KAKENHI-PLANNED-16H06501
  • [Presentation] Extrinsic and intrinsic inhibition of T cell response by co-inhibitory receptors, TIGIT and CD96.2019

    • Author(s)
      Yanase N, Machiyama H, Toyota H, Furuhata M, Hata K, Takehara T, Wakamatsu E, Yokosuka T
    • Organizer
      第48回日本免疫学会学術集会
    • Data Source
      KAKENHI-INTERNATIONAL-16K21731
  • [Presentation] 分子イメージングが拓くT細胞活性化機構の解明とがん免疫応答ーチェックポイント分子とキメラ抗原受容体CARのシグナルソーム形成ー2019

    • Author(s)
      横須賀忠
    • Organizer
      Immuno-Oncology Forum in Ehime
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-16H06495
  • [Presentation] Extrinsic and intrinsic inhibition of T cell response by co-inhibitory receptors, TIGIT and CD96.2019

    • Author(s)
      Yanase N, Machiyama H, Toyota H, Furuhata M, Hata K, Takehara T, Wakamatsu E, Yokosuka T
    • Organizer
      第48回日本免疫学会総会
    • Data Source
      KAKENHI-PROJECT-17H03600
  • [Presentation] 分子イメージングが拓くT細胞活性化機構の解明とがん免疫療法2019

    • Author(s)
      横須賀忠
    • Organizer
      第81回日本血液学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K22545
  • [Presentation] Programmed cell death 2 forms coinhibitory microclusters that directly attenuate T cell receptor signaling by recruiting phosphatase SHP22019

    • Author(s)
      Takehara T, Wakamatsu E, Machiyama H, Yanase N, Hata K, Toyoda H, Furuhata M, Yasuda H, Soejima K, Yokosuka T.
    • Organizer
      American Association for Cancer Research
    • Int'l Joint Research
    • Data Source
      KAKENHI-ORGANIZER-16H06495
  • [Presentation] Extrinsic and intrinsic inhibition of T cell response by co-inhibitory receptors, TIGIT and CD96.2019

    • Author(s)
      Yanase N, Machiyama H, Toyota H, Furuhata M, Hata K, Takehara T, Wakamatsu E, Yokosuka T
    • Organizer
      第48回日本免疫学会総会
    • Data Source
      KAKENHI-PLANNED-16H06501
  • [Presentation] 分子イメージングが拓くT細胞活性化機構の解明とがん免疫応答ーチェックポイント分子とキメラ抗原受容体CARのシグナルソーム形成ー2019

    • Author(s)
      横須賀忠
    • Organizer
      Immuno-Oncology Forum in Ehime
    • Invited
    • Data Source
      KAKENHI-INTERNATIONAL-16K21731
  • [Presentation] 分子イメージングが拓くがん免疫応答とT細胞活性化メカニズムの解明2019

    • Author(s)
      横須賀忠
    • Organizer
      第75回日本口腔科学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K22545
  • [Presentation] 分子イメージングが拓くT細胞活性化機構の解明とがん免疫療法 -免疫チェックポイント分子とキメラ抗原受容体のシグナルソーム-2019

    • Author(s)
      横須賀忠
    • Organizer
      Scientific Exchange Meeting in 北九州2019
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K22545
  • [Presentation] Programmed cell death 2 forms coinhibitory microclusters that directly attenuate T cell receptor signaling by recruiting phosphatase SHP22019

    • Author(s)
      Takehara T, Wakamatsu E, Machiyama H, Yanase N, Hata K, Toyoda H, Furuhata M, Yasuda H, Soejima K, Yokosuka T
    • Organizer
      American Association fro Cancer Reserach
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03600
  • [Presentation] 分子イメージングが拓くがん免疫応答とT細胞活性化メカニズムの解明2019

    • Author(s)
      横須賀忠
    • Organizer
      第75回日本口腔科学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H03600
  • [Presentation] 分子イメージングが拓くがん免疫応答とT細胞活性化メカニズムの解明2019

    • Author(s)
      横須賀忠
    • Organizer
      第75回日本口腔科学会学術集会
    • Invited
    • Data Source
      KAKENHI-PLANNED-16H06501
  • [Presentation] Different requirement of the coreceptors CD4 and CD8 for initiation of T cell activation.2019

    • Author(s)
      Machiyama H Wakamatsu E, Hata K, Yanase N, Furuhata M, Toyota H, Yokosuka T
    • Organizer
      第48回日本免疫学会総会
    • Data Source
      KAKENHI-PROJECT-19K22545
  • [Presentation] Extrinsic and intrinsic inhibition of T cell response by co-inhibitory receptors, TIGIT and CD96.2019

    • Author(s)
      Yanase N, Machiyama H, Toyota H, Furuhata M, Hata K, Takehara T, Wakamatsu E, Yokosuka T
    • Organizer
      第48回日本免疫学会総会
    • Data Source
      KAKENHI-PROJECT-19K22545
  • [Presentation] 多様なT細胞シグナルソームによる腫瘍およびネオ・セルフ抗原認識の分子機構2019

    • Author(s)
      横須賀忠、若松英、矢那瀬紀子、秦喜久美、竹原朋宏、西航、町山裕亮
    • Organizer
      第92回日本生化学会大会
    • Data Source
      KAKENHI-INTERNATIONAL-16K21731
  • [Presentation] Programmed cell death 2 forms coinhibitory microclusters that directly attenuate T cell receptor signaling by recruiting the phosphatase SHP2.2019

    • Author(s)
      Takehara T, Wakamatsu E, Machiyama H, Yanase N, Toyota H, Furuhata M, Koichi F, Soejima K, Yokosuka T
    • Organizer
      第48回日本免疫学会総会
    • Data Source
      KAKENHI-PLANNED-16H06501
  • [Presentation] 末梢T細胞ではLckと共受容体CD4/CD8との協調的クラスター形成よって初期のTCRシグナルが惹起される2019

    • Author(s)
      町山裕亮、若松英、秦喜久美、矢那瀬紀子、古畑昌枝、豊田博子、横須賀忠
    • Organizer
      Kyot T cell Conference 第29回学術集会
    • Data Source
      KAKENHI-INTERNATIONAL-16K21731
  • [Presentation] Molecular imaging unveils a mechanism of T cell activation regulation by immune checkpoint microclusters.2019

    • Author(s)
      Tadashi Yokosuka, Ei Wakamatsu, Tomohiro Takehara, Kikumi Hata, Noriko Yanase,Hiroaki Machiyama
    • Organizer
      The 23rd JFCR-ISCC New Antitumor Agents under Development in the US, Europe and Japan
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03600
  • [Presentation] 末梢T細胞ではLckと共受容体CD4/CD8との協調的クラスター形成よって初期のTCRシグナルが惹起される2019

    • Author(s)
      町山裕亮、若松英、秦喜久美、矢那瀬紀子、古畑昌枝、豊田博子、横須賀忠
    • Organizer
      Kyot T cell Conference 第29回学術集会
    • Data Source
      KAKENHI-ORGANIZER-16H06495
  • [Presentation] 多様なT細胞シグナルソームによる腫瘍およびネオ・セルフ抗原認識の分子機構2019

    • Author(s)
      横須賀忠、若松英、矢那瀬紀子、秦喜久美、竹原朋宏、西航、町山裕亮
    • Organizer
      第92回日本生化学会大会
    • Invited
    • Data Source
      KAKENHI-PLANNED-16H06501
  • [Presentation] Indirect suppression of CD4+ T cell activation by LAG3-mediated trogocytosis of MHC Class II.2019

    • Author(s)
      Wakamatsu E, Machiyama H, Toyota H, Furuhata M, Hata K, Yanase N, Yokosuka T
    • Organizer
      第48回日本免疫学会総会
    • Data Source
      KAKENHI-PLANNED-16H06501
  • [Presentation] 分子イメージングが拓くT細胞活性化機構の解明とがん免疫療法2019

    • Author(s)
      横須賀忠
    • Organizer
      第81回日本血液学会学術集会
    • Invited
    • Data Source
      KAKENHI-INTERNATIONAL-16K21731
  • [Presentation] CARマイクロクラスターによる腫瘍抗原の認識とCAR-T細胞活性化の時空間的制御機構2019

    • Author(s)
      横須賀忠、若松英、矢那瀬紀子、秦喜久美、竹原朋宏、西航、町山裕亮
    • Organizer
      第23回日本がん免疫学会総会
    • Invited
    • Data Source
      KAKENHI-PLANNED-16H06501
  • [Presentation] 分子イメージングが拓くT細胞活性化機構の解明とがん免疫療法2019

    • Author(s)
      横須賀忠
    • Organizer
      第81回日本血液学会学術集会
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-16H06495
  • [Presentation] Different requirement of the coreceptors CD4 and CD8 for initiation of T cell activation.2019

    • Author(s)
      Machiyama H Wakamatsu E, Hata K, Yanase N, Furuhata M, Toyota H, Yokosuka T
    • Organizer
      第48回日本免疫学会総会
    • Data Source
      KAKENHI-PLANNED-16H06501
  • [Presentation] 分子イメージングが拓くがん免疫応答とT細胞活性化メカニズムの解明2019

    • Author(s)
      横須賀忠
    • Organizer
      第75回日本口腔科学会学術集会
    • Invited
    • Data Source
      KAKENHI-INTERNATIONAL-16K21731
  • [Presentation] Different requirement of the coreceptors CD4 and CD8 for initiation of T cell activation.2019

    • Author(s)
      Machiyama H Wakamatsu E, Hata K, Yanase N, Furuhata M, Toyota H, Yokosuka T
    • Organizer
      第48回日本免疫学会学術集会
    • Data Source
      KAKENHI-ORGANIZER-16H06495
  • [Presentation] 免疫チェックポイント療法はなぜ効くのか?分子イメージングが明らかにするT細胞活性化の時空間的制御機構2018

    • Author(s)
      横須賀忠
    • Organizer
      国立がんセンター東がん免疫セミナー
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-16H06495
  • [Presentation] 胸腺ダブルポジティブT細胞におけるc-Cblのシグナルソーム形成と胸腺選択との相関2018

    • Author(s)
      秦喜久美、町山裕亮、若松英、豊田博子、古畑昌枝、矢那瀬紀子、横須賀忠
    • Organizer
      Kyot T cell Conference 第28回学術集会
    • Data Source
      KAKENHI-INTERNATIONAL-16K21731
  • [Presentation] 免疫チェックポイント療法はなぜ効くのか?分子イメージングが明らかにするT細胞活性化の時空間的制御機構2018

    • Author(s)
      横須賀忠
    • Organizer
      国立がんセンター東がん免疫セミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H03600
  • [Presentation] がん免疫と分子イメージング先端的研究ー免疫チェックポイント分子とキメラ抗原受容体CARの分子メカニズムー2018

    • Author(s)
      横須賀忠
    • Organizer
      第77回日本癌学会学術総会
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-16H06495
  • [Presentation] Cooperative regulation of thymic selection by receptor endocytosis and signal strength through TCR and E3 ubiquitin ligase c-Cbl microcluster formation.2018

    • Author(s)
      Kikumi Hata, Hiroaki Machiyama, Noriko Yanase, Masae Furuhata, Hiroko Toyota, Ei Wakamatsu, Tadashi Yokosuka
    • Organizer
      第47回日本免疫学会学術集会
    • Data Source
      KAKENHI-PROJECT-17H03600
  • [Presentation] Molecular imaging unveils a mechanism of T cell activation regulation by immune checkpoint microclusters.2018

    • Author(s)
      Tadashi Yokosuka, Ei Wakamatsu, Tomohiro Takehara, Kikumi Hata, Noriko Yanase,Hiroaki Machiyama
    • Organizer
      The 23rd JFCR-ISCC New Antitumor Agents under Development in the US, Europe and Japan
    • Int'l Joint Research
    • Data Source
      KAKENHI-ORGANIZER-16H06495
  • [Presentation] がん免疫と分子イメージング先端的研究ー免疫チェックポイント分子とキメラ抗原受容体CARの分子メカニズムー2018

    • Author(s)
      横須賀忠
    • Organizer
      第77回日本癌学会学術総会
    • Invited
    • Data Source
      KAKENHI-INTERNATIONAL-16K21731
  • [Presentation] Cooperative regulation of thymic selection by receptor endocytosis and signal strength through TCR and E3 ubiquitin ligase c-Cbl microcluster formation.2018

    • Author(s)
      Kikumi Hata, Hiroaki Machiyama, Noriko Yanase, Masae Furuhata, Hiroko Toyota, Ei Wakamatsu, Tadashi Yokosuka
    • Organizer
      第47回日本免疫学会学術集会
    • Data Source
      KAKENHI-ORGANIZER-16H06495
  • [Presentation] 胸腺ダブルポジティブT細胞におけるc-Cblのシグナルソーム形成と胸腺選択との相関2018

    • Author(s)
      秦喜久美、町山裕亮、若松英、豊田博子、古畑昌枝、矢那瀬紀子、横須賀忠
    • Organizer
      Kyoto T cell Conference 第28回学術集会
    • Data Source
      KAKENHI-PROJECT-17H03600
  • [Presentation] Single molecule imaging unveils a distinct difference in Lck-dynamics between CD4+ and CD8+ T cells.2018

    • Author(s)
      Hiroaki Machiyama, Ei Wakamatsu, Noriko Yanase, Kikumi Hata, Masae Furuhata, Hiroko Toyota, Tadashi Yokosuka
    • Organizer
      第47回日本免疫学会学術集会
    • Data Source
      KAKENHI-INTERNATIONAL-16K21731
  • [Presentation] Single molecule imaging unveils a distinct difference in Lck-dynamics between CD4+ and CD8+ T cells.2018

    • Author(s)
      Hiroaki Machiyama, Ei Wakamatsu, Noriko Yanase, Kikumi Hata, Masae Furuhata, Hiroko Toyota, Tadashi Yokosuka
    • Organizer
      第47回日本免疫学会学術集会
    • Data Source
      KAKENHI-ORGANIZER-16H06495
  • [Presentation] 分子イメージングが明らかにするマイクロクラスターによるT細胞活性化制御機構ー免疫チェックポイント受容体とCARのマイクロクラスターー2018

    • Author(s)
      横須賀忠
    • Organizer
      第一三共株式会社細胞治療研究所講演会
    • Invited
    • Data Source
      KAKENHI-PLANNED-16H06501
  • [Presentation] チェックポイントから学ぶことー科学的思考は疫学や過去の結論から新天地を築くー2018

    • Author(s)
      横須賀忠
    • Organizer
      第35回日本呼吸器外科学会総会
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-16H06495
  • [Presentation] 免疫チェックポイント阻害剤と癌治療の進歩ー臨床と基礎の視点からー2018

    • Author(s)
      横須賀忠
    • Organizer
      第22回日本がん分子標的治療学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H03600
  • [Presentation] チェックポイントから学ぶことー科学的思考は疫学や過去の結論から新天地を築くー2018

    • Author(s)
      横須賀忠
    • Organizer
      第35回日本呼吸器外科学会総会
    • Invited
    • Data Source
      KAKENHI-INTERNATIONAL-16K21731
  • [Presentation] Molecular imaging of the hCD19 CAR signalosomes, “CAR microclusters”.2018

    • Author(s)
      Yanase Noriko, Machiyama Hiroaki, Wakamatsu Ei, Toyota Hiroko, Furuhata Masae, Hata Kikumi, Mamonkin Maksim, Brenner Malcolm K, Yokosuka Tadashi
    • Organizer
      第47回日本免疫学会学術集会
    • Data Source
      KAKENHI-PLANNED-16H06501
  • [Presentation] Dynamics of the PI3K signaling pathway induced by a T cell costimulator, ICOS.2018

    • Author(s)
      Yokosuka Tadashi, Wakamatsu Ei, Yanase Noriko, Toyota Hiroko, Furuhata Masae, Hata Kikumi, Machiyama Hiroaki
    • Organizer
      第47回日本免疫学会学術集会
    • Data Source
      KAKENHI-PLANNED-16H06501
  • [Presentation] 分子イメージングが解明する免疫チェックポイント療法によるT細胞の疲弊解除とその分子メカニズム2018

    • Author(s)
      横須賀忠
    • Organizer
      中外製薬株式会社セミナー
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-16H06495
  • [Presentation] イメージングが拓くT細胞活性化の時空間的制御機構ー免疫チェックポイントはなぜ効くのか?ー2018

    • Author(s)
      横須賀忠
    • Organizer
      第12回肝免疫フォーラム
    • Invited
    • Data Source
      KAKENHI-PLANNED-16H06501
  • [Presentation] チェックポイントから学ぶこと~科学的思考は疫学や過去の結論から新天地を築く~2018

    • Author(s)
      横須賀忠
    • Organizer
      第35回日本呼吸器外科学会総会
    • Invited
    • Data Source
      KAKENHI-PLANNED-16H06501
  • [Presentation] 分子イメージングが解明する免疫チェックポイント療法によるT細胞の疲弊解除とその分子メカニズム2018

    • Author(s)
      横須賀忠
    • Organizer
      中外製薬株式会社セミナー
    • Invited
    • Data Source
      KAKENHI-PLANNED-16H06501
  • [Presentation] 分子イメージングが明らかにするマイクロクラスターによるT細胞活性化制御機構ー免疫チェックポイント受容体とCARのマイクロクラス ターー2018

    • Author(s)
      横須賀忠
    • Organizer
      第一三共株式会社細胞治療研究所講演会
    • Invited
    • Data Source
      KAKENHI-INTERNATIONAL-16K21731
  • [Presentation] 胸腺ダブルポジティブT細胞におけるc-Cblのシグナルソーム形成と胸腺選択との相関2018

    • Author(s)
      秦喜久美、町山裕亮、若松英、豊田博子、古畑昌枝、矢那瀬紀子、横須賀忠
    • Organizer
      Kyoto T cell Conference 第28回学術集会
    • Data Source
      KAKENHI-PLANNED-16H06501
  • [Presentation] 分子イメージングによる免疫チェックポイント療法によるT細胞の疲弊解除とその分子メカニズムの解明2018

    • Author(s)
      横須賀忠、若松英、矢那瀬紀子、竹原朋宏、秦喜久美、町山裕亮
    • Organizer
      第22回日本がん免疫学会総会
    • Invited
    • Data Source
      KAKENHI-PLANNED-16H06501
  • [Presentation] Molecular imaging unveils a mechanism of T cell activation regulation by immune checkpoint microclusters.2018

    • Author(s)
      Tadashi Yokosuka, Ei Wakamatsu, Tomohiro Takehara, Kikumi Hata, Noriko Yanase,Hiroaki Machiyama
    • Organizer
      The 23rd JFCR-ISCC New Antitumor Agents under Development in the US, Europe and Japan
    • Int'l Joint Research
    • Data Source
      KAKENHI-INTERNATIONAL-16K21731
  • [Presentation] イメージングが拓くT細胞活性化の時空間的制御機構ー免疫チェックポイントはなぜ効くのか?ー2018

    • Author(s)
      横須賀忠
    • Organizer
      第12回肝免疫フォーラム
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H03600
  • [Presentation] 分子イメージングが拓くT細胞活性化機構の解明とがん免疫応答ー;免疫チェックポイント分子とキメラ抗原受容体CARのシグナルソーム形成ー2018

    • Author(s)
      横須賀忠
    • Organizer
      三重大学院医学研究科セミナー
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-16H06495
  • [Presentation] Molecular imaging unveils spatiotemporal regulation of T cell activation by immune checkpoint receptors.2018

    • Author(s)
      Yokosuka T
    • Organizer
      The 1st International Cancer Research Symposium of Training Plan for Oncology Professionals
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06501
  • [Presentation] Molecular imaging unveils spatiotemporal regulation of T cell activation by immune checkpoint receptors2018

    • Author(s)
      Yokosuka T
    • Organizer
      The 1st International Cancer Research Symposium of Training Plan for Oncology Professionals
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-16H06495
  • [Presentation] 分子イメージングが明らかにするT細胞活性化の時空間的制御機構~免疫チェックポイント分子とCAR~2018

    • Author(s)
      横須賀忠
    • Organizer
      第59回日本肺癌学会学術集会
    • Invited
    • Data Source
      KAKENHI-PLANNED-16H06501
  • [Presentation] Dynamics of the PI3K signaling pathway induced by a T cell costimulator, ICOS.2018

    • Author(s)
      Yokosuka Tadashi, Wakamatsu Ei, Yanase Noriko, Toyota Hiroko, Furuhata Masae, Hata Kikumi, Machiyama Hiroaki
    • Organizer
      第47回日本免疫学会学術集会
    • Data Source
      KAKENHI-ORGANIZER-16H06495
  • [Presentation] 免疫チェックポイント療法はなぜ効くのか?分子イメージングが明らかにするT細胞活性化の時空間的制御機構2018

    • Author(s)
      横須賀忠
    • Organizer
      国立がんセンター東がん免疫セミナー
    • Invited
    • Data Source
      KAKENHI-PLANNED-16H06501
  • [Presentation] 分子イメージングが解明する免疫チェックポイント療法によるT細胞の疲弊解除とその分子メカニズム2018

    • Author(s)
      横須賀忠
    • Organizer
      中外製薬株式会社セミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H03600
  • [Presentation] 分子イメージングが明らかにするT細胞活性化の時空間的制御機構~免疫チェックポイント分子とCAR~2018

    • Author(s)
      横須賀忠
    • Organizer
      第59回日本肺癌学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H03600
  • [Presentation] 免疫チェックポイント阻害剤と癌治療の進歩ー臨床と基礎の視点からー2018

    • Author(s)
      横須賀忠
    • Organizer
      第22回日本がん分子標的治療学会学術集会
    • Invited
    • Data Source
      KAKENHI-INTERNATIONAL-16K21731
  • [Presentation] チェックポイントから学ぶことー科学的思考は疫学や過去の結論から新天地を築くー2018

    • Author(s)
      横須賀忠
    • Organizer
      第35回日本呼吸器外科学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H03600
  • [Presentation] Molecular imaging of the hCD19 CAR signalosomes, “CAR microclusters”.2018

    • Author(s)
      Yanase Noriko, Machiyama Hiroaki, Wakamatsu Ei, Toyota Hiroko, Furuhata Masae, Hata Kikumi, Mamonkin Maksim, Brenner Malcolm K, Yokosuka Tadashi
    • Organizer
      第47回日本免疫学会学術集会
    • Data Source
      KAKENHI-PROJECT-17H03600
  • [Presentation] 分子イメージングが拓くT細胞活性化機構の解明とがん免疫応答~免疫チェックポイント分子とキメラ抗原受容体CARのシグナルソーム形成~2018

    • Author(s)
      横須賀忠
    • Organizer
      三重大学院医学研究科セミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H03600
  • [Presentation] Dynamics of the PI3K signaling pathway induced by a T cell costimulator, ICOS.2018

    • Author(s)
      Yokosuka Tadashi, Wakamatsu Ei, Yanase Noriko, Toyota Hiroko, Furuhata Masae, Hata Kikumi, Machiyama Hiroaki
    • Organizer
      第47回日本免疫学会学術集会
    • Data Source
      KAKENHI-PROJECT-17H03600
  • [Presentation] 分子イメージングが拓くT細胞活性化機構の解明とがん免疫応答~免疫チェックポイント分子とキメラ抗原受容体CARのシグナルソーム形成~2018

    • Author(s)
      横須賀忠
    • Organizer
      三重大学院医学研究科セミナー
    • Invited
    • Data Source
      KAKENHI-PLANNED-16H06501
  • [Presentation] 分子イメージングが明らかにするT細胞活性化の時空間的制御機構ー免疫チェックポイント分子とCARー2018

    • Author(s)
      横須賀忠
    • Organizer
      第59回日本肺癌学会学術集会
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-16H06495
  • [Presentation] 分子イメージングによる免疫チェックポイント療法によるT細胞の疲弊解除とその分子メカニズムの解明2018

    • Author(s)
      横須賀忠、若松英、矢那瀬紀子、竹原朋宏、秦喜久美、町山裕亮
    • Organizer
      第22回日本がん免疫学会総会
    • Data Source
      KAKENHI-INTERNATIONAL-16K21731
  • [Presentation] Single molecule imaging unveils a distinct difference in Lck-dynamics between CD4+ and CD8+ T cells.2018

    • Author(s)
      Hiroaki Machiyama, Ei Wakamatsu, Noriko Yanase, Kikumi Hata, Masae Furuhata, Hiroko Toyota, Tadashi Yokosuka
    • Organizer
      第47回日本免疫学会学術集会
    • Data Source
      KAKENHI-PLANNED-16H06501
  • [Presentation] 分子イメージングが解明する免疫チェックポイント療法によるT細胞の疲弊解除とその分子メカニズム2018

    • Author(s)
      横須賀忠
    • Organizer
      中外製薬株式会社セミナー
    • Invited
    • Data Source
      KAKENHI-INTERNATIONAL-16K21731
  • [Presentation] 分子イメージングによる免疫チェックポイント療法によるT細胞の疲弊解除とその分子メカニズムの解明2018

    • Author(s)
      横須賀忠、若松英、矢那瀬紀子、竹原朋宏、秦喜久美、町山裕亮
    • Organizer
      第22回日本がん免疫学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H03600
  • [Presentation] 分子イメージングが明らかにするマイクロクラスターによるT細胞活性化制御機構ー免疫チェックポイント受容体とCARのマイクロクラスターー2018

    • Author(s)
      横須賀忠
    • Organizer
      第一三共株式会社細胞治療研究所講演会
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-16H06495
  • [Presentation] Cooperative regulation of thymic selection by receptor endocytosis and signal strength through TCR and E3 ubiquitin ligase c-Cbl microcluster formation.2018

    • Author(s)
      Kikumi Hata, Hiroaki Machiyama, Noriko Yanase, Masae Furuhata, Hiroko Toyota, Ei Wakamatsu, Tadashi Yokosuka
    • Organizer
      第47回日本免疫学会学術集会
    • Data Source
      KAKENHI-PLANNED-16H06501
  • [Presentation] Molecular imaging of the hCD19 CAR signalosomes, “CAR microclusters”.2018

    • Author(s)
      Yanase Noriko, Machiyama Hiroaki, Wakamatsu Ei, Toyota Hiroko, Furuhata Masae, Hata Kikumi, Mamonkin Maksim, Brenner Malcolm K, Yokosuka Tadashi
    • Organizer
      第47回日本免疫学会学術集会
    • Data Source
      KAKENHI-INTERNATIONAL-16K21731
  • [Presentation] 分子イメージングが明らかにするマイクロクラスターによるT細胞活性化制御機構ー免疫チェックポイント受容体とCARのマイクロクラスターー2018

    • Author(s)
      横須賀忠
    • Organizer
      第一三共株式会社細胞治療研究所講演会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H03600
  • [Presentation] Single molecule imaging unveils a distinct difference in Lck-dynamics between CD4+ and CD8+ T cells.2018

    • Author(s)
      Hiroaki Machiyama, Ei Wakamatsu, Noriko Yanase, Kikumi Hata, Masae Furuhata, Hiroko Toyota, Tadashi Yokosuka
    • Organizer
      第47回日本免疫学会学術集会
    • Data Source
      KAKENHI-PROJECT-17H03600
  • [Presentation] がん免疫と分子イメージング先端的研究~免疫チェックポイント分子とキメラ抗原受容体CARの分子メカニズム~2018

    • Author(s)
      横須賀忠
    • Organizer
      第77回日本癌学会学術総会
    • Invited
    • Data Source
      KAKENHI-PLANNED-16H06501
  • [Presentation] がん免疫と分子イメージング先端的研究ー免疫チェックポイント分子とキメラ抗原受容体CARの分子メカニズムー2018

    • Author(s)
      横須賀忠
    • Organizer
      第77回日本癌学会学術総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H03600
  • [Presentation] Molecular imaging unveils spatiotemporal regulation of T cell activation by immune checkpoint receptors.2018

    • Author(s)
      Yokosuka T,
    • Organizer
      The 1st International Cancer Research Symposium of Training Plan for Oncology Professionals
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-INTERNATIONAL-16K21731
  • [Presentation] Molecular imaging unveils spatiotemporal regulation of T cell activation by immune checkpoint receptors.2018

    • Author(s)
      Yokosuka T
    • Organizer
      The 1st International Cancer Research Symposium of Training Plan for Oncology Professionals
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03600
  • [Presentation] 分子イメージングによる免疫チェックポイント療法によるT細胞の疲弊解除とその分子メカニズムの解明2018

    • Author(s)
      横須賀忠、若松英、矢那瀬紀子、竹原朋宏、秦喜久美、町山裕亮
    • Organizer
      第22回日本がん免疫学会総会
    • Data Source
      KAKENHI-ORGANIZER-16H06495
  • [Presentation] 胸腺ダブルポジティブT細胞におけるc-Cblのシグナルソーム形成と胸腺選択との相関2018

    • Author(s)
      秦喜久美、町山裕亮、若松英、豊田博子、古畑昌枝、矢那瀬紀子、横須賀忠
    • Organizer
      Kyot T cell Conference 第28回学術集会
    • Data Source
      KAKENHI-ORGANIZER-16H06495
  • [Presentation] 分子イメージングが拓くT細胞活性化機構の解明とがん免疫応答ー;免疫チェックポイント分子とキメラ抗原受容体CARのシグナルソーム形 成ー2018

    • Author(s)
      横須賀忠
    • Organizer
      三重大学院医学研究科セミナー
    • Invited
    • Data Source
      KAKENHI-INTERNATIONAL-16K21731
  • [Presentation] Dynamics of the PI3K signaling pathway induced by a T cell costimulator, ICOS.2018

    • Author(s)
      Yokosuka Tadashi, Wakamatsu Ei, Yanase Noriko, Toyota Hiroko, Furuhata Masae, Hata Kikumi, Machiyama Hiroaki
    • Organizer
      第47回日本免疫学会学術集会
    • Data Source
      KAKENHI-INTERNATIONAL-16K21731
  • [Presentation] 免疫チェックポイント阻害剤と癌治療の進歩~臨床と基礎の視点から~2018

    • Author(s)
      横須賀忠
    • Organizer
      第22回日本がん分子標的治療学会学術集会
    • Invited
    • Data Source
      KAKENHI-PLANNED-16H06501
  • [Presentation] 免疫チェックポイント阻害剤と癌治療の進歩ー臨床と基礎の視点からー2018

    • Author(s)
      横須賀忠
    • Organizer
      第22回日本がん分子標的治療学会学術集会
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-16H06495
  • [Presentation] Molecular imaging of the hCD19 CAR signalosomes, “CAR microclusters”.2018

    • Author(s)
      Yanase Noriko, Machiyama Hiroaki, Wakamatsu Ei, Toyota Hiroko, Furuhata Masae, Hata Kikumi, Mamonkin Maksim, Brenner Malcolm K, Yokosuka Tadashi
    • Organizer
      第47回日本免疫学会学術集会
    • Data Source
      KAKENHI-ORGANIZER-16H06495
  • [Presentation] 分子イメージングが明らかにするT細胞活性化の時空間的制御機構ー免疫チェックポイント分子とCARー2018

    • Author(s)
      横須賀忠
    • Organizer
      第59回日本肺癌学会学術集会
    • Invited
    • Data Source
      KAKENHI-INTERNATIONAL-16K21731
  • [Presentation] Molecular imaging unveils a mechanism of T cell activation regulation by immune checkpoint microclusters.2018

    • Author(s)
      Tadashi Yokosuka, Ei Wakamatsu, Tomohiro Takehara, Kikumi Hata, Noriko Yanase,Hiroaki Machiyama
    • Organizer
      The 23rd JFCR-ISCC New Antitumor Agents under Development in the US, Europe and Japan
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06501
  • [Presentation] Cooperative regulation of thymic selection by receptor endocytosis and signal strength through TCR and E3 ubiquitin ligase c-Cbl microcluster formation.2018

    • Author(s)
      Kikumi Hata, Hiroaki Machiyama, Noriko Yanase, Masae Furuhata, Hiroko Toyota, Ei Wakamatsu, Tadashi Yokosuka
    • Organizer
      第47回日本免疫学会学術集会
    • Data Source
      KAKENHI-INTERNATIONAL-16K21731
  • [Presentation] 免疫チェックポイント療法はなぜ効くのか?分子イメージングが明らかにするT細胞活性化の時空間的制御機構2018

    • Author(s)
      横須賀忠
    • Organizer
      国立がんセンター東がん免疫セミナー
    • Invited
    • Data Source
      KAKENHI-INTERNATIONAL-16K21731
  • [Presentation] イメージングが拓くT細胞活性化の時空間的制御機構ーT細胞シグナルソームの視点から免疫チェックポイント分子を解釈するー2017

    • Author(s)
      横須賀忠
    • Organizer
      Meet The Specialist 2017
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H03600
  • [Presentation] イメージングが拓くT細胞活性化の時空間的制御機構 -シグナルソームの視点から免疫チェックポイントを解釈する-2017

    • Author(s)
      横須賀忠
    • Organizer
      Expert Seminar of Immunology
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H03600
  • [Presentation] イメージングが拓く免疫チェックポイント分子によるT細胞活性化の時空間的制御機構2017

    • Author(s)
      横須賀忠
    • Organizer
      第2回肺癌バイオカンファレンス
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H03600
  • [Presentation] イメージンブが拓くT細胞活性化の時空間的制御機構2017

    • Author(s)
      横須賀忠
    • Organizer
      Expert Seminar of Immunology
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-16H06495
  • [Presentation] Microclusters as a signaling unit for T cell receptor endocytosis2017

    • Author(s)
      Machiyama H, Hata K, Yanase N, Hashimoto-Tane A, Saito T, Yokosuka T.
    • Organizer
      The 7th International Symposium of Kyoto T Cell Conference
    • Place of Presentation
      京都大学(京都・京都市)
    • Year and Date
      2017-03-13
    • Data Source
      KAKENHI-INTERNATIONAL-16K21731
  • [Presentation] Microclusters as a signaling unit for T cell receptor endocytosis2017

    • Author(s)
      Machiyama H, Hata K, Yanase N, Hashimoto-Tane A, Saito T, Yokosuka T.
    • Organizer
      The 7th International Symposium of Kyoto T Cell Conference
    • Place of Presentation
      京都大学(京都府・京都市)
    • Year and Date
      2017-03-13
    • Data Source
      KAKENHI-ORGANIZER-16H06495
  • [Presentation] Microclusters as a functional unit for endocytosis of TCRs2017

    • Author(s)
      Yokosuka T, Machiyama H, Hata K, Yanase N, Hashimoto-Tane A, Siato T
    • Organizer
      第46回日本免疫学会総会学術集会
    • Data Source
      KAKENHI-PLANNED-16H06501
  • [Presentation] イメージングが拓く免疫チェックポイント分子によるT細胞活性化の時空間的制御機構2017

    • Author(s)
      横須賀忠
    • Organizer
      第14回日本免疫治療学研究会学術集会
    • Place of Presentation
      東京大学(東京都)
    • Year and Date
      2017-02-11
    • Invited
    • Data Source
      KAKENHI-PLANNED-16H06501
  • [Presentation] イメージングが拓く免疫チェックポイント分子によるT細胞活性化の時空間的制御機構2017

    • Author(s)
      横須賀忠
    • Organizer
      第2回肺癌バイオカンファレンス
    • Invited
    • Data Source
      KAKENHI-PLANNED-16H06501
  • [Presentation] Microclusters as a functional unit for endocytosis of TCRs2017

    • Author(s)
      Yokosuka T, Machiyama H, Hata K, Yanase N, Hashimoto-Tane A, Siato T
    • Organizer
      第46回日本免疫学会総会学術集会
    • Data Source
      KAKENHI-PROJECT-17H03600
  • [Presentation] イメージングが拓く免疫チェックポイント分子による細胞活性化の時空間的制御機構2017

    • Author(s)
      横須賀忠
    • Organizer
      第32回日本肺癌学会ワークショップ
    • Invited
    • Data Source
      KAKENHI-PLANNED-16H06501
  • [Presentation] イメージングが拓く免疫チェックポイント分子によるT細胞活性化の時空間的制御機構2017

    • Author(s)
      横須賀忠
    • Organizer
      第14回日本免疫治療学研究会学術集会
    • Place of Presentation
      東京大学(東京・文京区)
    • Year and Date
      2017-02-11
    • Data Source
      KAKENHI-INTERNATIONAL-16K21731
  • [Presentation] 分子イメージングが明らかにするT細胞の活性化制御機構- がんの免疫チェックポイント療法はなぜ効くのか? -2017

    • Author(s)
      横須賀忠
    • Organizer
      第71回東邦医学会総会
    • Invited
    • Data Source
      KAKENHI-PLANNED-16H06501
  • [Presentation] 分子イメージングが明らかにするT細胞の活性化制御機構- がんの免疫チェックポイント療法はなぜ効くのか? -2017

    • Author(s)
      横須賀忠
    • Organizer
      第71回東邦医学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H03600
  • [Presentation] イメージングが拓くT細胞活性化の時空間的制御機構 -シグナルソームの視点から免疫チェックポイントを解釈する-2017

    • Author(s)
      横須賀忠
    • Organizer
      Expert Seminar of Immunology
    • Invited
    • Data Source
      KAKENHI-PLANNED-16H06501
  • [Presentation] イメージングが拓くT細胞活性化の時空間的制御機構ーT細胞シグナルソームの視点から免疫チェックポイント分子を解釈するー2017

    • Author(s)
      横須賀忠
    • Organizer
      Meet The Specialist 2017
    • Invited
    • Data Source
      KAKENHI-PLANNED-16H06501
  • [Presentation] Microclusters as a signaling unit for T cell receptor endocytosis.2017

    • Author(s)
      Machiyama H, Hata K, Yanase N, Hashimoto-Tane A, Saito T, Yokosuka T.
    • Organizer
      The 7th International Symposium of Kyoto T Cell Conference
    • Place of Presentation
      京都大学(京都府)
    • Year and Date
      2017-03-13
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06501
  • [Presentation] イメージングが拓く免疫チェックポイント分子によるT細胞活性化の時空間的制御機構2017

    • Author(s)
      横須賀忠
    • Organizer
      上総イムノオンコロジーセミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H03600
  • [Presentation] イメージンブが拓くT細胞活性化の時空間的制御機構2017

    • Author(s)
      横須賀忠
    • Organizer
      Expert Seminar of Immunology
    • Invited
    • Data Source
      KAKENHI-INTERNATIONAL-16K21731
  • [Presentation] イメージングが拓く免疫チェックポイント分子によるT細胞活性化の時空間的制御機構2017

    • Author(s)
      横須賀忠
    • Organizer
      上総イムノオンコロジーセミナー
    • Invited
    • Data Source
      KAKENHI-PLANNED-16H06501
  • [Presentation] イメージングが拓く免疫チェックポイント分子による細胞活性化の時空間的制御機構2017

    • Author(s)
      横須賀忠
    • Organizer
      第32回日本肺癌学会ワークショップ
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H03600
  • [Presentation] イメージングが拓く免疫チェックポイント分子によるT細胞活性化の時空間的制御機構2017

    • Author(s)
      横須賀忠
    • Organizer
      第14回日本免疫治療学研究会学術集会
    • Place of Presentation
      東京大学(東京都・文京区)
    • Year and Date
      2017-02-11
    • Data Source
      KAKENHI-ORGANIZER-16H06495
  • [Presentation] B細胞の分化・機能におけるアルギニンメチル化酵素PRMT1の役割の解析2016

    • Author(s)
      秦喜久美、矢那瀬紀子、水口純一郎、横須賀忠
    • Organizer
      第26回京都T細胞カンファランス
    • Place of Presentation
      大津
    • Year and Date
      2016-05-20
    • Data Source
      KAKENHI-PUBLICLY-15H01194
  • [Presentation] Balance of T cell activation and suppression controlled by Cbl-b-mediated ubiquitination of TCR microclusters2016

    • Author(s)
      Tadashi Yokosuka
    • Organizer
      MEXT Research Project Symposium
    • Place of Presentation
      理化学研究所(横浜)
    • Year and Date
      2016-03-02
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-15H01194
  • [Presentation] Microclusters as a functional unit for the endocytosis of TCRs2016

    • Author(s)
      Yokosuka T, Machiyama H, Hata K, Yanase N, Hashimoto-Tane A, Saito T.
    • Organizer
      第45回日本免疫学会学術集会
    • Place of Presentation
      沖縄コンベンションセンター(沖縄・宜野湾市)
    • Year and Date
      2016-12-06
    • Data Source
      KAKENHI-INTERNATIONAL-16K21731
  • [Presentation] Microclusters as a functional unit for the endocytosis of TCRs2016

    • Author(s)
      Yokosuka T, Machiyama H, Hata K, Yanase N, Hashimoto-Tane A, Saito T.
    • Organizer
      第45回日本免疫学会学術集会
    • Place of Presentation
      沖縄コンベンションセンター(沖縄県・宜野湾市)
    • Year and Date
      2016-12-06
    • Data Source
      KAKENHI-ORGANIZER-16H06495
  • [Presentation] Microclusters as a functional unit for the endocytosis of TCRs2016

    • Author(s)
      Yokosuka T, Machiyama H, Hata K, Yanase N, Hashimoto-Tane A, Saito T.
    • Organizer
      第45回日本免疫学会学術集会
    • Place of Presentation
      沖縄コンベンションセンター(沖縄)
    • Year and Date
      2016-12-06
    • Data Source
      KAKENHI-PLANNED-16H06501
  • [Presentation] Balance of T cell activation and suppression controlled by Cbl-b-mediated ubiquitination of TCR microclusters2016

    • Author(s)
      Tadashi Yokosuka
    • Organizer
      MEXT Research Project Symposium
    • Place of Presentation
      理化学研究所(横浜)
    • Year and Date
      2016-03-02
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24590590
  • [Presentation] Cytoskeletal regulation of the clustering of a Ras-GEF, RasGRP1, upon T cell activation2015

    • Author(s)
      Tadashi Yokosuka, Akiko Hashimoto-Tane, Masae Furuhata, Hiroko Toyoda, Takashi Saito
    • Organizer
      第44回日本免疫学会総会学術集会
    • Place of Presentation
      札幌コンベンションセンター(札幌)
    • Year and Date
      2015-11-18
    • Data Source
      KAKENHI-PUBLICLY-15H01194
  • [Presentation] 分子イメージングが拓くT細胞活性化の時空間的制御機構2015

    • Author(s)
      横須賀忠
    • Organizer
      第14回四国免疫フォーラム
    • Place of Presentation
      愛媛大学(松山)
    • Year and Date
      2015-06-20
    • Invited
    • Data Source
      KAKENHI-PROJECT-24590590
  • [Presentation] Cytoskeletal regulation of the clustering of a Ras-GEF, RasGRP1, upon T cell activation2015

    • Author(s)
      Tadashi Yokosuka, Akiko Hashimoto-Tane, Takashi Saito
    • Organizer
      第25回京都T細胞カンファランス
    • Place of Presentation
      京都大学(京都)
    • Year and Date
      2015-05-15
    • Data Source
      KAKENHI-PROJECT-24590590
  • [Presentation] Cytoskeletal regulation of the clustering of a Ras-GEF, RasGRP1, upon T cell activation2015

    • Author(s)
      Tadashi Yokosuka, Akiko Hashimoto-Tane, Takashi Saito
    • Organizer
      第25回京都T細胞カンファランス
    • Place of Presentation
      京都大学(京都)
    • Year and Date
      2015-05-15
    • Data Source
      KAKENHI-PUBLICLY-15H01194
  • [Presentation] Cytoskeletal regulation of the clustering of a Ras-GEF, RasGRP1, upon T cell activation2015

    • Author(s)
      Tadashi Yokosuka, Akiko Hashimoto-Tane, Masae Furuhata, Hiroko Toyoda, Takashi Saito
    • Organizer
      第44回日本免疫学会総会学術集会
    • Place of Presentation
      札幌コンベンションセンター(札幌)
    • Year and Date
      2015-11-18
    • Data Source
      KAKENHI-PROJECT-24590590
  • [Presentation] 分子イメージングが拓くT細胞活性化の時空間的制御機構2015

    • Author(s)
      横須賀忠
    • Organizer
      第14回四国免疫フォーラム
    • Place of Presentation
      愛媛大学(松山)
    • Year and Date
      2015-06-20
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-15H01194
  • [Presentation] Distinct signalosome formation by two Ras-GEFs to activate the Ras-MAPK pathway in T cell signaling2013

    • Author(s)
      Tadashi Yokosuka, Akiko Hashimoto-Tane, Takashi Saito
    • Organizer
      第42回日本免疫学会総会学術集会
    • Place of Presentation
      幕張メッセ(千葉)
    • Data Source
      KAKENHI-PUBLICLY-25113725
  • [Presentation] Distinct signalosome formation by two Ras-GEFs to activate the Ras-MAPK pathway in T cell signaling2013

    • Author(s)
      Tadashi Yokosuka, Akiko Hashimoto-Tane, Takashi Saito
    • Organizer
      第42回日本免疫学会総会学術集会
    • Place of Presentation
      幕張メッセ(千葉)
    • Data Source
      KAKENHI-PROJECT-24590590
  • [Presentation] Negative costimulatory microclusters inhibiting T cell-mediated inflammation2013

    • Author(s)
      Tadashi Yokosuka, Akiko Hashimoto-Tane, Takashi Saito
    • Organizer
      JST-CREST International Symposium
    • Place of Presentation
      学術総合センター(東京)
    • Year and Date
      2013-02-12
    • Data Source
      KAKENHI-PUBLICLY-23113521
  • [Presentation] Negative costimulatory microclusters inhibiting T cell-mediated inflammation2013

    • Author(s)
      Tadashi Yokosuka, Akiko Hashimoto-Tane, Takashi Saito
    • Organizer
      JST-CREST International Symposium
    • Place of Presentation
      学術総合センター(東京)
    • Data Source
      KAKENHI-PROJECT-24590590
  • [Presentation] Arp2/3 complex-mediated actin-nucleation supports T cell receptor microcluster2013

    • Author(s)
      Akiko Hashimoto-Tane, Tadashi Yokosuka, Takashi Saito
    • Organizer
      第42回日本免疫学会総会学術集会
    • Place of Presentation
      千葉
    • Data Source
      KAKENHI-PROJECT-24590590
  • [Presentation] Dynamic and cytoskeletal regulation of T cell activation2013

    • Author(s)
      Takashi Saito, Tadashi Yokosuka, Akiko Hashimoto-Tane
    • Organizer
      RIKEN RCAI-University of Michigan Joint Workshop
    • Place of Presentation
      Detroit, USA
    • Invited
    • Data Source
      KAKENHI-PROJECT-24590590
  • [Presentation] Basilic, a lymphoid-specific protein essential for CD28 costimulation and regulatory T cell development2013

    • Author(s)
      Marie Malissen, Yinming Liangv, Margot Cucchetti, Romain Roncagalli, Tadashi Yokosuka, Takashi Saito, Christoph Wulfing, Bernard Malissen,
    • Organizer
      International Congress of Immunology 2013
    • Place of Presentation
      Italia Milano
    • Data Source
      KAKENHI-PROJECT-24590590
  • [Presentation] Arp2/3 complex-mediated actin-nucleation supports T cell receptor microcluster2013

    • Author(s)
      kiko Hashimoto-Tane, Tadashi Yokosuka, Takashi Saito
    • Organizer
      第42回日本免疫学会総会学術集会
    • Place of Presentation
      幕張メッセ(千葉)
    • Data Source
      KAKENHI-PUBLICLY-25113725
  • [Presentation] Basilic, a lymphoid-specific protein essential for CD28 costimulation and regulatory T cell development2013

    • Author(s)
      Marie Malissen, Yinming Liangv, Margot Cucchetti, Romain Roncagalli, Tadashi Yokosuka, Takashi Saito, Christoph Wulfing, Bernard Malissen
    • Organizer
      International Congress of Immunology 2013
    • Place of Presentation
      Italia Milano
    • Data Source
      KAKENHI-PUBLICLY-25113725
  • [Presentation] Dynamic and cytoskeletal regulation of T cell activation2013

    • Author(s)
      Takashi Saito, Tadashi Yokosuka, Akiko Hashimoto-Tane
    • Organizer
      RIKEN RCAI-University of Michigan Joint Workshop
    • Place of Presentation
      Detroit, USA
    • Year and Date
      2013-01-16
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-23113521
  • [Presentation] Negative regulation of TCR signaling by PD-1 microcluster2012

    • Author(s)
      Yokosuka, T., Saito, T.
    • Organizer
      Keystone Symposia-Regulation of Lymphocyte Signaling
    • Place of Presentation
      Keystone, CO, USA(招待講演)
    • Year and Date
      2012-03-15
    • Data Source
      KAKENHI-PROJECT-19109005
  • [Presentation] 免疫シナプス形成を担うダイニンによるT細胞抗原受容体運搬の分子機構2012

    • Author(s)
      多根(橋本)彰子、横須賀忠、斉藤隆
    • Organizer
      第85回日本薬理学会年会
    • Place of Presentation
      京都
    • Year and Date
      2012-03-08
    • Data Source
      KAKENHI-PROJECT-21590548
  • [Presentation] T細胞の抗原認識と免疫応答を司る活性化シグナルユニットの研究2012

    • Author(s)
      横須賀忠
    • Organizer
      第4回千葉医学会賞受賞講演
    • Place of Presentation
      千葉大学医学部(千葉)
    • Year and Date
      2012-06-20
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-23113521
  • [Presentation] Negative regulation of TCR signaling by PD-1 microclusters2012

    • Author(s)
      Yokosuka T, Saito T
    • Organizer
      The 4th Joint RCAI-LIAI Workshop
    • Place of Presentation
      La Jolla, CA. USA
    • Year and Date
      2012-07-08
    • Data Source
      KAKENHI-PROJECT-21590548
  • [Presentation] Essential role for intra- and intermolecular SH3-GUK interactions of CARMA1 in antigen receptor-induced NF-κB and JNK activation2012

    • Author(s)
      Hiromitsu Hara, Tadashi Yokosuka, Hideki Hirakawa, Chitose Ishihara, Shinsuke Yasukawa, Haruhiko Koseki, Hiroki Yoshida, Takashi Saito
    • Organizer
      第41回日本免疫学会総会学術集会
    • Place of Presentation
      神戸国際会議場(神戸)
    • Data Source
      KAKENHI-PROJECT-24590590
  • [Presentation] Negative regulation of TCR signaling by PD-1 microcluster2012

    • Author(s)
      Yokosuka, T. and Saito, T
    • Organizer
      Keystone Symposia-Regulation of Lymphocyte Signaling
    • Place of Presentation
      Keystone, CO. USA
    • Year and Date
      2012-03-15
    • Data Source
      KAKENHI-PROJECT-19109005
  • [Presentation] Negative regulation of TCR signaling by PD-1 microcluster2012

    • Author(s)
      Yokosuka T, Saito T
    • Organizer
      Keystone Symposia-Regulation of Lymphocyte Signaling
    • Place of Presentation
      Keystone, CO. USA
    • Data Source
      KAKENHI-PROJECT-21590548
  • [Presentation] Essential role for intra- and intermolecular SH3-GUK interactions of CARMA1 in antigen receptor-induced NF-κB and JNK activation2012

    • Author(s)
      Hiromitsu Hara, Tadashi Yokosuka, Hideki Hirakawa, Chitose Ishihara, Shinsuke Yasukawa, Haruhiko Koseki, Hiroki Yoshida, Takashi Saito
    • Organizer
      第41回日本免疫学会総会学術集会
    • Place of Presentation
      神戸国際会議場(神戸)
    • Year and Date
      2012-12-05
    • Data Source
      KAKENHI-PUBLICLY-23113521
  • [Presentation] The PD-1 microclusters : negative costimulatory signalosomes directly targeting TCR downstream2011

    • Author(s)
      Yokosuka T, Saito T
    • Organizer
      第40回日本免疫学会総会学術集会
    • Place of Presentation
      千葉
    • Data Source
      KAKENHI-PROJECT-21590548
  • [Presentation] Dynamic regulation of T cell activation by TCR microclusters2011

    • Author(s)
      Tadashi Yokosuka
    • Organizer
      2nd CSI/JSI/KAI Joint symposium on Immunology
    • Place of Presentation
      大阪(招待講演)
    • Year and Date
      2011-12-06
    • Data Source
      KAKENHI-PUBLICLY-23113521
  • [Presentation] Imaging of T cell activation regulation :-Negative regulation of TCR signaling by PD-1 microcluster-2011

    • Author(s)
      Yokosuka T, Saito T
    • Organizer
      University of Michigan-RCAI Joint Workshop
    • Place of Presentation
      Yokohama
    • Data Source
      KAKENHI-PROJECT-21590548
  • [Presentation] Dynamic regulation of T cell activation by TCR microclusters2011

    • Author(s)
      Yokosuka, T.
    • Organizer
      2^<nd> CSI/JSI/KAI Joint Symposium on Immunology "Regulation of Immune Responses in Health and Diseases"
    • Place of Presentation
      Osaka(日中韓免疫シンポジウム)(招待講演)
    • Year and Date
      2011-12-06
    • Data Source
      KAKENHI-PROJECT-19109005
  • [Presentation] Dynamic regulation of T-cell activation by TCR microclusters2011

    • Author(s)
      Yokosuka T
    • Organizer
      RIKEN 2011 Joint Retreat
    • Place of Presentation
      Kakegawa
    • Data Source
      KAKENHI-PROJECT-21590548
  • [Presentation] 分子イメージングが拓くT細胞活性化の制御機構2011

    • Author(s)
      横須賀忠
    • Organizer
      第20回日本バイオイメージング学会学術集会
    • Place of Presentation
      千歳(招待講演)
    • Year and Date
      2011-09-02
    • Data Source
      KAKENHI-PROJECT-19109005
  • [Presentation] 免疫シナプスにおけるダイニンによるT細胞受容体ミクロクラスター運搬の分子機構2011

    • Author(s)
      多根(橋本)彰子、横須賀忠、斉藤隆
    • Organizer
      第40回日本免疫学会総会学術集会
    • Place of Presentation
      千葉
    • Year and Date
      2011-11-29
    • Data Source
      KAKENHI-PROJECT-19109005
  • [Presentation] PD-1マイクロクラスターによるT細胞活性化制御機構の解明2011

    • Author(s)
      横須賀忠
    • Organizer
      第21回Kyoto T Cell Conference
    • Place of Presentation
      京都
    • Year and Date
      2011-06-10
    • Data Source
      KAKENHI-PUBLICLY-23113521
  • [Presentation] Dynein-driven transport of TCR microclusters forms Immune synapse and regulates T cell activation2011

    • Author(s)
      Hashimoto-Tane A, Yokosuka T, Sakuma M, Saito T.
    • Organizer
      第84回日本薬理学会年会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-21590548
  • [Presentation] The PD-1 microclusters : negative costimulatory signalosome directly targeting TCR downstream2011

    • Author(s)
      Tadashi Yokosuka
    • Organizer
      第40回日本免疫学会総会学術集会
    • Place of Presentation
      千葉(招待講演)
    • Year and Date
      2011-11-28
    • Data Source
      KAKENHI-PUBLICLY-23113521
  • [Presentation] PD-1マイクロクラスターによるT細胞活性化制御機構の解明2011

    • Author(s)
      横須賀忠
    • Organizer
      第21回Kyoto T Cell Conference
    • Place of Presentation
      京都
    • Year and Date
      2011-06-10
    • Data Source
      KAKENHI-PROJECT-21590548
  • [Presentation] 分子イメージングが拓くT細胞活性化の制御機構2011

    • Author(s)
      横須賀忠
    • Organizer
      第20回日本バイオイメージング学会学術集会
    • Place of Presentation
      千歳
    • Data Source
      KAKENHI-PROJECT-21590548
  • [Presentation] 分子イメージングが拓くT細胞活性化の制御機構2011

    • Author(s)
      横須賀忠
    • Organizer
      第20回日本バイオイメージング学会学術集会
    • Place of Presentation
      千歳(招待講演)
    • Year and Date
      2011-09-02
    • Data Source
      KAKENHI-PROJECT-21590548
  • [Presentation] Dynamic regulation of T cell activation by TCR microclusters2011

    • Author(s)
      Yokosuka T
    • Organizer
      2nd CSI/JSI/KAI Joint Symposium on Immunology "Regulation of Immune Responses in Health and Diseases"
    • Place of Presentation
      Osaka
    • Data Source
      KAKENHI-PROJECT-21590548
  • [Presentation] Spatiotemporal regulation of T cell activation and costimulation2011

    • Author(s)
      Saito T, Yokosuka T, Hashimoto-Tane A.
    • Organizer
      1st POSTECH International Symposium of Bio-Imaging
    • Place of Presentation
      Pohang, Korea
    • Data Source
      KAKENHI-PROJECT-21590548
  • [Presentation] The PD-1 microclusters : negative costimulatory signalosome directly targeting TCR downstream2011

    • Author(s)
      Tadashi Yokosuka
    • Organizer
      第40回日本免疫学会総会学術集会
    • Place of Presentation
      千葉(招待講演)
    • Year and Date
      2011-11-28
    • Data Source
      KAKENHI-PROJECT-21590548
  • [Presentation] 免疫シナプスにおけるダイニンによるT細胞受容体ミクロクラスター運搬の分子機構2011

    • Author(s)
      多根(橋本)彰子、横須賀忠、斉藤隆
    • Organizer
      第40回日本免疫学会総会学術集会
    • Place of Presentation
      千葉
    • Data Source
      KAKENHI-PROJECT-21590548
  • [Presentation] Dynamic Regulation of T-cell Activation by TCR Microclusters2011

    • Author(s)
      Yokosuka T
    • Organizer
      東京理科大学生命科学研究所セミナー
    • Place of Presentation
      野田
    • Year and Date
      2011-01-11
    • Data Source
      KAKENHI-PROJECT-21590548
  • [Presentation] SH3-Guk domain regulating Carmal micro-cluster formation is essential for antigen receptor-induced NF-κB activation2011

    • Author(s)
      Hara, H., Yokosuka, T., et al
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2011-12-15
    • Data Source
      KAKENHI-PROJECT-19109005
  • [Presentation] PD-1マイクロクラスターによるT細胞活性化制御機構の解明2011

    • Author(s)
      横須賀忠
    • Organizer
      Kyoto T Cell Conference
    • Place of Presentation
      Kyoto
    • Data Source
      KAKENHI-PROJECT-21590548
  • [Presentation] Spatiotemporal regulation of T cell co-stimulation2011

    • Author(s)
      Saito T, Yokosuka T, Tane-Hashimoto A.
    • Organizer
      FASEB Summer Conferences Signal Transduction in the Immune System
    • Place of Presentation
      Snowmass Village, CO
    • Data Source
      KAKENHI-PROJECT-21590548
  • [Presentation] 分子イメージングが拓くT細胞活性化の制御機構2011

    • Author(s)
      横須賀忠
    • Organizer
      第20回日本バイオイメージング学会学術集会
    • Place of Presentation
      千歳(招待講演)
    • Year and Date
      2011-09-02
    • Data Source
      KAKENHI-PUBLICLY-23113521
  • [Presentation] SH3-Guk domain regulating Carma1 micro-cluster formation is essential for antigen receptor-induced NF-κB activation2011

    • Author(s)
      Hara H, Yokosuka T, Ishihara C, Yasukawa S, Hirakawa H, Iizasa E, Yoshida H, Saito T.
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      Yokohama
    • Data Source
      KAKENHI-PROJECT-21590548
  • [Presentation] Visualising the dynamics of immune synapse by TIRF2011

    • Author(s)
      Saito, T., Yokosuka, T., Tane-Hashimoto, A., Sakata-Sogawa, K., Tokunaga, M.
    • Organizer
      XXVI Congress of the International Society for Advancement of Cytometry(CYTO2011)
    • Place of Presentation
      Baltimore, MD, USA
    • Year and Date
      2011-05-24
    • Data Source
      KAKENHI-PROJECT-19109005
  • [Presentation] Dynamic regulation of T cell activation by TCR microclusters2011

    • Author(s)
      Tadashi Yokosuka
    • Organizer
      2nd CSI/JSI/KAI Joint symposium on Immunology
    • Place of Presentation
      大阪(招待講演)
    • Year and Date
      2011-12-06
    • Data Source
      KAKENHI-PROJECT-21590548
  • [Presentation] A. Spatiotemporal regulation of T cell activation and costimulation2011

    • Author(s)
      Saito, T., Yokosuka, T., Hashimoto-Tane
    • Organizer
      1^<st> POSTECH International Symposium of Bio-Imaging
    • Place of Presentation
      Pohang, Korea
    • Year and Date
      2011-09-30
    • Data Source
      KAKENHI-PROJECT-19109005
  • [Presentation] Visualising the dynamics of immune synapse by TIRF2011

    • Author(s)
      Saito, T., Yokosuka, T., Tane-Hashimoto, A.
    • Organizer
      XXVI Congress of the International Society for Advancement of Cytometry (CYTO2011)
    • Place of Presentation
      Baltimore, MD, USA(招待講演)
    • Year and Date
      2011-05-24
    • Data Source
      KAKENHI-PROJECT-19109005
  • [Presentation] Visualising the dynamics of immune synapse by TIRF2011

    • Author(s)
      Saito T, Yokosuka T, Tane-Hashimoto A, Sakata-Sogawa K, Tokunaga M.
    • Organizer
      XXVI Congress of the International Society for Advancement of Cytometry(CYTO2011)
    • Place of Presentation
      Baltimore, MD, USA
    • Data Source
      KAKENHI-PROJECT-21590548
  • [Presentation] Spatiotemporal regulation of T cell activation and costimulation2011

    • Author(s)
      Saito, T., Yokosuka, T., Tane-Hashimoto, A.
    • Organizer
      1^<st> POSTECH International Symposium of Bio-Imaging
    • Place of Presentation
      Pophang, Korea(招待講演)
    • Year and Date
      2011-09-30
    • Data Source
      KAKENHI-PROJECT-19109005
  • [Presentation] Spatiotemporal regulation of T cell co-stimulation2011

    • Author(s)
      Saito, T., Yokosuka, T., Tane-Hashimoto, A.
    • Organizer
      FASEB Summer Conferences-Signal Transduction in the Immune System
    • Place of Presentation
      Snowmass Village, CO
    • Year and Date
      2011-06-23
    • Data Source
      KAKENHI-PROJECT-19109005
  • [Presentation] The PD-1 microclusters : negative costimulatory signalosomes directly targeting TCR downstream2011

    • Author(s)
      Yokosuka, T., Saito, T.
    • Organizer
      第40回日本免疫学会総会学術集会
    • Place of Presentation
      千葉(招待講演)
    • Year and Date
      2011-11-28
    • Data Source
      KAKENHI-PROJECT-19109005
  • [Presentation] Spatiotemporal regulation of T cell co-stimulation2011

    • Author(s)
      Saito, T., Yokosuka, T., Tane-Hashimoto, A.
    • Organizer
      FASEB Summer Conferences-Signal Transduction in the Immune System
    • Place of Presentation
      Snowmass Village, CO, USA(招待講演)
    • Year and Date
      2011-06-23
    • Data Source
      KAKENHI-PROJECT-19109005
  • [Presentation] Dynamic regulation of T-cell costimulation by TCR microclusters and the c-SMAC2010

    • Author(s)
      Yokosuka T, Sakata-Sogawa K, Tokunaga M, Saito T
    • Organizer
      14th International Congress of Immunology
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-21590548
  • [Presentation] Dynamic Regulation of T-cell Activation by TCR Microclusters2010

    • Author(s)
      Tadashi Yokosuka
    • Organizer
      第16回武田科学振興財団生命科学シンポジウム(The 16th Takeda Science Foundation Symposium on Bioscience)
    • Place of Presentation
      東京
    • Year and Date
      2010-12-01
    • Data Source
      KAKENHI-PROJECT-21590548
  • [Presentation] 分子イメージングが拓くT細胞活性化の制御機構2010

    • Author(s)
      横須賀忠
    • Organizer
      第2回バイオフロンティアセミナー「免疫・疾患制御に向けたイメージング解析」
    • Place of Presentation
      東京
    • Year and Date
      2010-11-18
    • Data Source
      KAKENHI-PROJECT-21590548
  • [Presentation] CRTAM confers late-stage activation of CD8+T cells to regulate retention within lymph node2010

    • Author(s)
      Takeuchi A, Itoh A, Yokosuka T, Ogasawara K, Saito T
    • Organizer
      14th International Congress of Immunology
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-21590548
  • [Presentation] Dynamic Regulation of T-cell Activation by TCR Microclusters2010

    • Author(s)
      Yokosuka T, Saito T
    • Organizer
      第16回武田科学振興財団生命科学シンポジウム
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-21590548
  • [Presentation] Dynamic regulation of T-cell costimulation by TCR microclusters and the c-SNAG2010

    • Author(s)
      Tadashi Yokosuka
    • Organizer
      14th International Congress of Immunology(第14回国際免疫学会議)
    • Place of Presentation
      神戸
    • Year and Date
      2010-08-23
    • Data Source
      KAKENHI-PROJECT-21590548
  • [Presentation] Dynamic regulation of T-cell costimulation by TCR microclusters and the c-SMAC2010

    • Author(s)
      Tadashi Yokosuka
    • Organizer
      第13回国際細胞膜研究フォーラム/第6回iCeMS国際シンポジウム
    • Place of Presentation
      京都市、ホテルフジタ京都
    • Year and Date
      2010-01-27
    • Data Source
      KAKENHI-PROJECT-21590548
  • [Presentation] Dynamic regulation of T-cell costimulation by TCR microclusters and the c-SMAC2010

    • Author(s)
      Tadashi Yokosuka
    • Organizer
      第13回国際細胞膜研究フォーラム/第6回iCeMS国際シンポジウム
    • Place of Presentation
      京都
    • Year and Date
      2010-01-27
    • Data Source
      KAKENHI-PROJECT-19109005
  • [Presentation] T細胞の免疫シナプス形成と胸腺選択性との機能的相関の解析2010

    • Author(s)
      横須賀忠、斉藤隆
    • Organizer
      第20回Kyoto T Cell Conference(KTCC)学術集会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-21590548
  • [Presentation] Dynein-mediated translocation of TCR microclusters along microtubules to form cSMAC2010

    • Author(s)
      Hashimoto-Tane A, Yokosuka T, Saito T.
    • Organizer
      Keystone Symposia(Breckenridge
    • Place of Presentation
      CO. USA
    • Data Source
      KAKENHI-PROJECT-21590548
  • [Presentation] Dynamic regulation of T-cell costimulation by TCR microclusters and the c-SMAC2010

    • Author(s)
      Yokosuka T
    • Organizer
      The 13th International Membrane Research Forum/The 6th iCeMS International Symposium, Featuring Membrane Meso Mechanisms
    • Place of Presentation
      Kyoto
    • Data Source
      KAKENHI-PROJECT-21590548
  • [Presentation] Dynein-mediated translocation of TCR microclusters along microtubules to form c-SMAC during T cell activation2010

    • Author(s)
      Hashimoto-Tane A, Yokosuka T, Sakuma M, Saito T.
    • Organizer
      14th International Congress of Immunology
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-21590548
  • [Presentation] Dynamic regulation of T cell co-stimulation by TCR-CD28 microclusters2009

    • Author(s)
      Yokosuka, T.
    • Organizer
      LIAI-RCAI Joint Workshop 2009
    • Place of Presentation
      横浜
    • Year and Date
      2009-01-07
    • Data Source
      KAKENHI-PROJECT-19109005
  • [Presentation] Dynamic regulation of T-cell costimulation by TCR microclusters2009

    • Author(s)
      Tadashi Yokosuka
    • Organizer
      FASEB Summer Research Conferences
    • Place of Presentation
      Snowmass Village(USA)
    • Year and Date
      2009-06-24
    • Data Source
      KAKENHI-PROJECT-21590548
  • [Presentation] Dynamic Regulation of T Cell Co-stimulation by TCR-CD28 Microclusters2009

    • Author(s)
      Yokosuka, T.
    • Organizer
      LIAI-RCAI Joint Workshop 2009-Regulation of Lymphocyte Function and Immune Responses
    • Place of Presentation
      横浜
    • Year and Date
      2009-01-07
    • Data Source
      KAKENHI-PROJECT-19590504
  • [Presentation] Dynamic regulation of T-cell costimulation by TCR microclusters and the c-SMAC2009

    • Author(s)
      Tadashi Yokosuka
    • Organizer
      第39回日本免疫学会総会・学術集会
    • Place of Presentation
      大阪市 国際会議場
    • Year and Date
      2009-12-03
    • Data Source
      KAKENHI-PROJECT-21590548
  • [Presentation] Dynamic assembly of signaling complex for positive and negative costimulation of T cell activation2009

    • Author(s)
      Yokosuka T and Saito T
    • Organizer
      The 5th International Workshop of Kyoto T Cell
    • Place of Presentation
      Kyoto
    • Data Source
      KAKENHI-PROJECT-21590548
  • [Presentation] Dynamic regulation of T-cell costimulation by TCR microclusters and the c-SMAC2009

    • Author(s)
      Tadashi Yokosuka
    • Organizer
      第39回日本免疫学会総会・学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2009-12-03
    • Data Source
      KAKENHI-PROJECT-19109005
  • [Presentation] Imaging of Immune Responses Dynamic regulation of T-cell costimulation by TCR microclusters and the c-SMAC2009

    • Author(s)
      Yokosuka T, Saito T
    • Organizer
      第39回日本免疫学会総会・学術集会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-21590548
  • [Presentation] T細胞活性化及びcSMAC形成につながる微小管モーター・ダイニンによるTCRミクロクラスターの移動2009

    • Author(s)
      橋本彰子(多根)、横須賀忠、斉藤隆
    • Organizer
      第39回日本免疫学会総会・学術集会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-21590548
  • [Presentation] Dynamic regulation of T-cell costimulation by TCR microclusters2009

    • Author(s)
      Tadashi Yokosuka
    • Organizer
      FASEB Summer Research Conferences-Signal Transduction in the Immune System
    • Place of Presentation
      Snowmass Village(USA)
    • Year and Date
      2009-06-24
    • Data Source
      KAKENHI-PROJECT-19109005
  • [Presentation] TCR microclusters move along microtubules in early T cell activation2009

    • Author(s)
      Hashimoto-Tane A, Yokosuka T, Ishihara C, Saito T.
    • Organizer
      The 5th International Workshop of Kyoto T Cell Conference
    • Place of Presentation
      Kyoto
    • Data Source
      KAKENHI-PROJECT-21590548
  • [Presentation] Dynamic regulation of T-cell costimulation by TCR microclusters2009

    • Author(s)
      Yokosuka T, Saito T
    • Organizer
      FASEB Summer Research Conferences
    • Place of Presentation
      Snowmass Village, CO
    • Data Source
      KAKENHI-PROJECT-21590548
  • [Presentation] Identification of a region in immunological synapse critical for T cell co-stimulation2008

    • Author(s)
      Yokosuka, T.
    • Organizer
      第38回日本免疫学会総会・学術集会
    • Place of Presentation
      京都
    • Year and Date
      2008-12-03
    • Data Source
      KAKENHI-PROJECT-19109005
  • [Presentation] Visualization of signaling complex upon T cell activation2008

    • Author(s)
      Yokosuka, T.
    • Organizer
      The 2nd joint symposium between immunology and imaging, WIP-iFReC,
    • Place of Presentation
      大阪
    • Year and Date
      2008-08-28
    • Data Source
      KAKENHI-PROJECT-19590504
  • [Presentation] T細胞の副刺激を制御する免疫シナプスの領域の同定/ Identification of a region in immunological synapse critical for T cell co-stimulation2008

    • Author(s)
      Yokosuka, T., Sogawa-Sakata, K., Tane-Hashimoto, A., Tokunaga, M., Dustine, ML., Saito, T.
    • Organizer
      第38回日本免疫学会総会・学術集会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-19590504
  • [Presentation] Dynamic Regulation of T Cell Co-stimulation by TCR-CD28 Microclusters2008

    • Author(s)
      Yokosuka, T. and Saito, T
    • Organizer
      RCAI-JSI International Symposium on Immunology 2008 : Regulation of Immune Homeostasis and Diseases
    • Place of Presentation
      Yokohama
    • Year and Date
      2008-06-26
    • Data Source
      KAKENHI-PROJECT-19109005
  • [Presentation] T細胞の副刺激を制御する免疫シナプスの領域の同定/Identification of a region in immunological synapse critical for T cell co-stimulation2008

    • Author(s)
      Yokosuka, T.
    • Organizer
      第38回日本免疫学会総会・学術集会
    • Place of Presentation
      京都
    • Year and Date
      2008-12-03
    • Data Source
      KAKENHI-PROJECT-19590504
  • [Presentation] TCR-CD28マイクロクラスターとc-SMACによるT細胞活性化の時空間的制御/Spatiotemporal regulations of T cell activation by a c-SMAC and TCR-CD28-microclusters2007

    • Author(s)
      Yokosuka, T.
    • Organizer
      第37回日本免疫学会総会・学術集会
    • Place of Presentation
      東京
    • Year and Date
      2007-11-21
    • Data Source
      KAKENHI-PROJECT-19590504
  • [Presentation] Spatiotemporal regulation of T cell activation by TCR-CD28-microclusters2007

    • Author(s)
      Yokosuka, T.
    • Organizer
      第7回日本蛋白質科学会年会(The7^<th>Annual Meeting of Protein Science Society of Japan)
    • Place of Presentation
      仙台
    • Year and Date
      2007-05-25
    • Data Source
      KAKENHI-PROJECT-19590504
  • [Presentation] TCR-CD28-マイクロクラスターによるT細胞活性化の時空間的制御2007

    • Author(s)
      横須賀忠
    • Organizer
      第7回日本蛋白質科学会年会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-19590504
  • [Presentation] Spatiotemporal regulation of T cell activation by TCR-CD28-microclusters2007

    • Author(s)
      Yokosuka, T.
    • Organizer
      第10回国際細胞膜研究フォーラム
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-19590504
  • [Presentation] TCR-CD28マイクロクラスターによるT細胞活性化の時空間的制御2007

    • Author(s)
      横須賀 忠
    • Organizer
      第17回Kyoto T Cell Coference(KTCC)学術集会
    • Place of Presentation
      京都
    • Year and Date
      2007-06-15
    • Data Source
      KAKENHI-PROJECT-19109005
  • [Presentation] Spatiotemporal regulation of T cell activation by TCR-CD28-microclusters2007

    • Author(s)
      Yokosuka, T.
    • Organizer
      13^<th>International Congress of Immunology
    • Place of Presentation
      Rio de Janeiro,Brazil
    • Year and Date
      2007-08-21
    • Data Source
      KAKENHI-PROJECT-19590504
  • [Presentation] TCR-CD28マイクロクラスターによるT細胞活性化の時空間的制御2007

    • Author(s)
      横須賀 忠
    • Organizer
      第17回Kyoto T Cell Coference(KTCC)学術集会
    • Place of Presentation
      京都
    • Year and Date
      2007-06-15
    • Data Source
      KAKENHI-PROJECT-19590504
  • [Presentation] Spatiotemporal regulation of lymphocyte activation-Signalsome,TCR-microcluster-2007

    • Author(s)
      Yokosuka, T.
    • Organizer
      National Academy of Engineering 2007 Japan-America Frontiers of Engineering Symposium(第7回日米先端工学シンポジウム)
    • Place of Presentation
      California,USA
    • Year and Date
      2007-11-05
    • Data Source
      KAKENHI-PROJECT-19590504
  • [Presentation] Spatiotemporal regulation of lymphocyte activation-Signalsome,TCR-microcluster-2007

    • Author(s)
      Yokosuka, T.
    • Organizer
      2007Japan-America Frontiers of Engineering Symposium
    • Place of Presentation
      Palo Alto,USA
    • Data Source
      KAKENHI-PROJECT-19109005
  • [Presentation] Spatiotemporal regulation of T cell activation by TCR-CD28-microclusters2007

    • Author(s)
      Yokosuka, T.
    • Organizer
      FASEB Summer Research Conferences-Signal Transduction in the Immune System
    • Place of Presentation
      Snowmass,USA
    • Data Source
      KAKENHI-PROJECT-19109005
  • [Presentation] Spatiotemporal regulation of T cell activation by TCR-CD28-microclusters2007

    • Author(s)
      Yokosuka, T., Sakata-Sogawa, K. Kobayashi, W., Hiroshima, M., Hashimoto-Tane, A., Tokunaga, M., Dustine M.L. and Saito, T. (Minisymposium) (20070821)
    • Organizer
      13th International Congress of Immunology
    • Place of Presentation
      リオデジャネイロ
    • Data Source
      KAKENHI-PROJECT-19590504
  • [Presentation] Spatiotemporal regulation of T cell activation by TCR-CD28-microclusters2007

    • Author(s)
      Yokosuka, T.
    • Organizer
      13^<th> International Congress of Immunology
    • Place of Presentation
      Rio de Janeiro,Brazil
    • Year and Date
      2007-08-21
    • Data Source
      KAKENHI-PROJECT-19109005
  • [Presentation] Spatiotemporal regulation of lymphocyte activation: Signalsome, TCR-microcluster2007

    • Author(s)
      Yokosuka, T.
    • Organizer
      National Academy of Engineering 2007 Japan-America Frontiers of Engineering Symposium 第7回日米先端工学シンポジウム
    • Place of Presentation
      パロアルト
    • Data Source
      KAKENHI-PROJECT-19590504
  • [Presentation] TCR-CD28マイクロクラスターとc-SMACによるT細胞活性化の時空間的制御Spatiotemporal regulations of T cell activation by a c-SMAC and TCR-CD28-microclusters2007

    • Author(s)
      Yokosuka, T., Sakata-Sogawa, Hashimoto-Tane, A., Tokunaga, M., Dustin, ML. and Saito, T.
    • Organizer
      第37回日本免疫学会総会・学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-19590504
  • [Presentation] Spatiotemporal regulation of T cell activation by TCR-CD28-microclusters2007

    • Author(s)
      Yokosuka, T.
    • Organizer
      FASEB Summer Research Conferences
    • Place of Presentation
      Colorado,USA
    • Year and Date
      2007-06-26
    • Data Source
      KAKENHI-PROJECT-19590504
  • [Presentation] Spatiotemporal regulation of T cell activation by TCR-CD28-microclusters2007

    • Author(s)
      Yokosuka, T.
    • Organizer
      第7回日本蛋白質科学会年会
    • Place of Presentation
      仙台
    • Year and Date
      2007-05-25
    • Data Source
      KAKENHI-PROJECT-19109005
  • [Presentation] TCR-CD28マイクロクラスターとc-SMACによるT細胞活性化の時空間的制御2007

    • Author(s)
      横須賀 忠
    • Organizer
      第37回日本免疫学会総会・学術集会
    • Place of Presentation
      東京
    • Year and Date
      2007-11-21
    • Data Source
      KAKENHI-PROJECT-19109005
  • [Presentation] Spatiotemporal regulation of lymphocyte activation : Signalsome2007

    • Author(s)
      Yokosuka, T
    • Organizer
      TCR-microcluster. National Academy of Engineering 2007 Japan-America Frontiers of Engineering Symposium
    • Place of Presentation
      Palo Alto, CA
    • Data Source
      KAKENHI-PROJECT-19109005
  • [Presentation] “Microsynapse” structure supporting TCR microclusters augments T cell activation

    • Author(s)
      Akiko Hashimoto-Tane, Tadashi Yokosuka, Takashi Saito
    • Organizer
      第42回日本免疫学会総会学術集会
    • Place of Presentation
      京都国際会議場(京都)
    • Year and Date
      2014-12-10 – 2014-12-12
    • Data Source
      KAKENHI-PROJECT-24590590
  • [Presentation] Molecular imaging unveils the dynamic regulation of T cell activation

    • Author(s)
      Tadashi Yokosuka, Akiko Hashimoto-Tane, Takashi Saito
    • Organizer
      第18回日本がん免疫学会総会
    • Place of Presentation
      ひめ銀ホール(松山)
    • Year and Date
      2014-07-30 – 2014-08-01
    • Invited
    • Data Source
      KAKENHI-PROJECT-24590590
  • [Presentation] Subcellular imaging of the E3 ubiquitin ligases, c-Cbl and Cbl-b, to control T cell activation signals through ubiquitin clustering at TCR microclusters

    • Author(s)
      Tadashi Yokosuka, Akiko Hashimoto-Tane, Takashi Saito
    • Organizer
      第42回日本免疫学会総会学術集会
    • Place of Presentation
      京都国際会議場(京都)
    • Year and Date
      2014-12-10 – 2014-12-12
    • Data Source
      KAKENHI-PUBLICLY-25113725
  • [Presentation] Molecular imaging unveils the dynamic regulation of T cell activation

    • Author(s)
      Tadashi Yokosuka, Akiko Hashimoto-Tane, Takashi Saito
    • Organizer
      第18回日本がん免疫学会総会
    • Place of Presentation
      ひめ銀ホール(松山)
    • Year and Date
      2014-07-30 – 2014-08-01
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-25113725
  • [Presentation] Distinct signalosome formation by two Ras-GEFs to activate the Ras-MAPK pathway in T cell signaling

    • Author(s)
      Tadashi Yokosuka, Akiko Hashimoto-Tane, Takashi Saito
    • Organizer
      第24回京都T細胞カンファランス
    • Place of Presentation
      京都大学(京都)
    • Year and Date
      2014-05-16 – 2014-05-17
    • Data Source
      KAKENHI-PROJECT-24590590
  • [Presentation] Subcellular imaging of the E3 ubiquitin ligases, c-Cbl and Cbl-b, to control T cell activation signals through ubiquitin clustering at TCR microclusters

    • Author(s)
      Tadashi Yokosuka, Akiko Hashimoto-Tane, Takashi Saito
    • Organizer
      第42回日本免疫学会総会学術集会
    • Place of Presentation
      京都国際会議場(京都)
    • Year and Date
      2014-12-10 – 2014-12-12
    • Data Source
      KAKENHI-PROJECT-24590590
  • [Presentation] Distinct signalosome formation by two Ras-GEFs to activate the Ras-MAPK pathway in T cell signaling

    • Author(s)
      Tadashi Yokosuka, Akiko Hashimoto-Tane, Takashi Saito
    • Organizer
      第24回京都T細胞カンファランス
    • Place of Presentation
      京都大学(京都)
    • Year and Date
      2014-05-16 – 2014-05-17
    • Data Source
      KAKENHI-PUBLICLY-25113725
  • [Presentation] T細胞の抗原認識と免疫応答を司る活性化シグナルユニットの研究

    • Author(s)
      横須賀忠
    • Organizer
      第4回千葉医学会賞受賞講演
    • Place of Presentation
      千葉大学医学部(千葉)
    • Invited
    • Data Source
      KAKENHI-PROJECT-24590590
  • [Presentation] “Microsynapse” structure supporting TCR microclusters augments T cell activation

    • Author(s)
      Akiko Hashimoto-Tane, Tadashi Yokosuka, Takashi Saito
    • Organizer
      第42回日本免疫学会総会学術集会
    • Place of Presentation
      京都国際会議場(京都)
    • Year and Date
      2014-12-10 – 2014-12-12
    • Data Source
      KAKENHI-PUBLICLY-25113725
  • 1.  松本 満 (60221595)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 2.  町山 裕亮 (40704606)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 23 results
  • 3.  SAITO Takashi (50205655)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 29 results
  • 4.  末永 忠広 (20396675)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  矢那瀬 紀子 (10210303)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 21 results
  • 6.  若松 英 (40632617)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  TANE Akiko
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 4 results
  • 8.  HATA Kikumi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 9.  FURUHATA Masae
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 10.  木村 弥生
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 11.  豊田 博子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 12.  東 みゆき
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 13.  黒崎 知博
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 14.  原 博満
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 15.  吉田 裕樹
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 16.  竹馬 俊介
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 17.  岡田 匡央
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 18.  近藤 泰介
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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