Fujiwara Noriko 藤原範子

… Alternative Names

FUJIWARA Noriko 藤原範子

Less

Researcher Number	10368532
Other IDs
Affiliation (Current)	2025: 兵庫医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2025: 兵庫医科大学, 医学部, 教授 2016 – 2023: 兵庫医科大学, 医学部, 教授 2008 – 2016: 兵庫医科大学, 医学部, 准教授 2003 – 2008: 兵庫医科大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Basic Section 59040:Nutrition science and health science-related / Nerve anatomy/Neuropathology / Applied health science / Neurology Except Principal Investigator Basic Section 59040:Nutrition science and health science-related / Applied health science / Pathological medical chemistry / Hygiene / Basic Section 59030:Physical education, and physical and health education-related / Environmental and hygienic pharmacy / Laboratory medicine / General medical chemistry / Applied health science
Keywords	Principal Investigator ALS / 筋萎縮性側索硬化症 / SOD1 / Zn-SOD / Cu / 凝集体 / 凝集 / アミロイド / モノクローナル抗体 / 酸化 … More / 抗体 / スーパーオキシドジスムターゼ / 分子動力学シミュレーション / エピトープ / 免疫組織染色 / Cu,Zn-スーパーオキシドディスムターゼ / モノクロ－ナル抗体 / QCM / タンパク質凝集 / conformational change / oxidation / monoclonal antibody / superoxide dismutase / amyotrophic lateral sclerosis / 銅代謝 / 脳神経疾患 / NMR / SOD / 構造解析 / 免疫療法 / チャージアイソマー / 構造変化 / MALDI-TOF-MS / 酸化的翻訳後修飾 / 筋萎縮性側索硬化症(ALS) … More Except Principal Investigator 酸化ストレス / 肥満 / 転写因子 / ChREBP / 糖・脂質代謝 / メタボリックシンドローム / 糖尿病 / 活性酸素 / SOD1 / 生活習慣病 / 抗肥満 / 褐色脂肪組織 / 鉄代謝 / 鉄 / スーパーオキシドジスムターゼ / 動脈硬化 / 阻害剤 / ミトコンドリア / スクラーゼ / 老化 / HB-EGF / Cu, Zn-SOD / SOD / Cu / EC-SOD / 鉄欠乏 / 細胞質型アコニターゼ / 細胞質型のアコニターゼ / 食品成分 / crebp / エネルギー代謝 / 神経発達障害 / 発達障害 / ドーパミントランスポーター / コミュニケーション障害 / 遺伝子発現制御 / ニトロ化ストレス / 抗肥満効果 / 褐色脂肪細胞 / UCP1 / スクロース / 代謝 / フェロトーシス / TIMP1 / MMP9 / コラーゲン / グリケーション / 脂肪肝 / NASH / 抗酸化酵素 / cleavage of oligosaccharides / LEC rat / sugar chain / reactive oxygen species / プロテオグリカン / ヒアルロン酸 / 銅イオン / トランスフェリン / グリコサミノグリカン / Zn-SOD / 糖鎖 / Cys111 / Cu,Zn-SOD / LECラット / 家族性筋萎縮性側策硬化症 / 活性酸素種 / arteriosclerosis / oxidative stress / superoxside dismutase / ROS / DNA傷害 / 核移行シグナル / 突然変異 / N型糖鎖 / FALS / 細胞外型SOD / 糖代謝 / グルコース / 行動 / 加齢 / モノアミン / 行動学 / 神経伝達 / N-結合型糖鎖 / メタボリック症候群 / 脂肪前駆細胞 / 高血圧症 / N結合型糖鎖修飾 / 細胞外型スーパーオキシドジスムターゼ / 予防医学 / Zn-SODノックアウトマウス / スーパーオキドジスムターゼ / 過酸化脂質 / ヒドロキシノネナール / Cu/Zn-SODノックアウトマウス / グルタチオンSトランスフェラーゼ / 腎臓 / SOD1ノックアウトマウス / 血管平滑筋 / 一酸化窒素 Less

Elucidation of the molecular mechanism of ALS causative protein aggregate formation and pathogenesisPrincipal Investigator
- Principal Investigator
  
  藤原範子
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Hyogo Medical University
食品成分によるChREBP活性化阻害を介したメタボリックシンドローム予防の解析
- Principal Investigator
  
  崎山晴彦
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Senri Kinran University
鉄欠乏は老化を促進するのか？：鉄含有酵素ACO1による生体防御機構の解明
- Principal Investigator
  
  吉原大作
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Hyogo Medical University
Elucidation of intracellular aggregation mechanism of ALS-causing protein and development of aggregation inhibitorPrincipal Investigator
- Principal Investigator
  
  藤原範子
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Hyogo Medical University
Elucidation of epigenetic control and NASH pathogenesis by nitrosative stress.
- Principal Investigator
  
  Suzuki Keiichiro
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Hyogo Medical University
The role of oxidative stress in developmental disorders
- Principal Investigator
  
  Yoshihara Daisaku
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59030:Physical education, and physical and health education-related
- Research Institution
  Hyogo Medical University
Improvement of metabolic syndrome by inhibiting activation of ChREBP
- Principal Investigator
  
  sakiyama haruhiko
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Senri Kinran University
  Hyogo Medical University
Anti-obesity effect by re-programming glycolysis and lipogenesis
- Principal Investigator
  
  Suzuki Keiichiro
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Hyogo Medical University
The role of iron in aging
- Principal Investigator
  
  Yoshihara Daisaku
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental and hygienic pharmacy
- Research Institution
  Hyogo Medical University
Mechanism on efffect of anti-obesity by chrebp deficiency
- Principal Investigator
  
  sakiyama haruhiko
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied health science
- Research Institution
  Hyogo Medical University
Elucidation of ALS pathophysiology using monoclonal antibodies that specifically recognizes SOD1 aggregatesPrincipal Investigator
- Principal Investigator
  
  FUJIWARA Noriko
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Applied health science
- Research Institution
  Hyogo Medical University
Elucidation of the mechanism of onset of fatty liver / NASH caused by oxidative stress
- Principal Investigator
  
  Suzuki Keiichiro
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied health science
- Research Institution
  Hyogo Medical University
Detection of nitrated molecules involved in sugar metabolism
- Principal Investigator
  
  Eguchi Hironobu
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Hyogo Medical University
The effect of ChREBP activation in the development of metabolic syndrome
- Principal Investigator
  
  SAKIYAMA HARUHIKO
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied health science
- Research Institution
  Hyogo Medical University
Effects of oxidative stress on brain function
- Principal Investigator
  
  SUZUKI Keiichiro
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied health science
- Research Institution
  Hyogo Medical University
Structure analysis of mutant SOD1 and ALS immunotherapy using new monoclonal antibodiesPrincipal Investigator
- Principal Investigator
  
  FUJIWARA Noriko
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Hyogo Medical University
Obesity and oxidative stress: involvement of SOD in the physiology of metabolic syndrome and atherosclerosis
- Principal Investigator
  
  OOKAWARA Tomomi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hygiene
- Research Institution
  Hyogo University of Health Sciences
The compensatory mechanism against oxidative stress in kidney dysfunction
- Principal Investigator
  
  SUZUKI Keiichiro
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Hyogo College of Medicine
The role of oxidized SOD1 on ALS using the new antibody against oxidized SOD1 (anti-C111ox-SOD1)Principal Investigator
- Principal Investigator
  
  FUJIWARA Noriko
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Hyogo College of Medicine
Anti-oxidative effect of EC-SOD and prevention of atherosclerosis in lifestyle-related diseases.
- Principal Investigator
  
  OOKAWARA Tomomi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hygiene
- Research Institution
  Hyogo University of Health Sciences
  Hyogo College of Medicine
Nuclear translocation of antioxidant enzymes and ROS metabolism
- Principal Investigator
  
  SUZUKI Keiichiro
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Hyogo College of Medicine
Conformational change in FALS-linked mutant Cu/Zn-SOD analyzed by monoclonal antibodiesPrincipal Investigator
- Principal Investigator
  
  FUJIWARA Noriko
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Hyogo College of Medicine
Nuclear translocation of antioxidant enzymes and ROS metabolism
- Principal Investigator
  
  SUZUKI Keiichirou
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Hyogo College of Medicine

[Book] 月刊細胞2017
- Author(s)
  崎山晴彦、中川勉、江口裕伸、吉原大作、藤原範子、鈴木敬一郎
- Total Pages
  4
- Publisher
  ニューサイエンス社
- Data Source
  KAKENHI-PROJECT-17K01883
[Book] 改訂2版　集中講義　生化学2017
- Author(s)
  鈴木敬一郎、本家孝一、大河原知水、藤原範子
- Total Pages
  410
- Publisher
  （株）メジカルビュー社
- Data Source
  KAKENHI-PROJECT-16K13060
[Book] 活性酸素の本当の姿2014
- Author(s)
  鈴木敬一郎, 藤原範子　他
- Publisher
  NAP limited
- Data Source
  KAKENHI-PROJECT-24500877
[Book] 酸化ストレスの医学2014
- Author(s)
  吉原大作、藤原範子、鈴木敬一郎
- Total Pages
  456
- Publisher
  診断と治療社
- Data Source
  KAKENHI-PROJECT-25350911
[Book] 活性酸素の生成・消去は日常茶飯事、活性酸素の本当の姿2014
- Author(s)
  藤原範子(鈴木敬一郎編)
- Publisher
  有限会社ナップ
- Data Source
  KAKENHI-PROJECT-23591259
[Book] Systems biology of free radicals and anti-oxidants2014
- Author(s)
  Eguchi H., Sakiyama H., Yoshihara D., Fujiwara N., Suzuki K.
- Total Pages
  4178
- Publisher
  Springer-Verlag
- Data Source
  KAKENHI-PROJECT-25350911
[Book] 酸化ストレスの医学　改訂第２版2014
- Author(s)
  吉原大作、藤原範子、鈴木敬一郎
- Total Pages
  456
- Publisher
  診断と治療社
- Data Source
  KAKENHI-PROJECT-24500877
[Book] Systems biology of free radicals and anti-oxidants2014
- Author(s)
  Eguchi H., Sakiyama H., Yoshihara D., Fujiwara N., Suzuki K
- Total Pages
  4178
- Publisher
  Springer-Verlag
- Data Source
  KAKENHI-PROJECT-24500877
[Book] 活性酸素の本当の姿2014
- Author(s)
  藤原範子, 鈴木敬一郎　他
- Publisher
  NAP limited
- Data Source
  KAKENHI-PROJECT-23591259
[Book] アミノ酸・タンパク質, 集中講義・生化学2011
- Author(s)
  藤原範子(鈴木敬一郎、本家孝一、大河原知水、藤原範子編)
- Publisher
  メジカルビュー社
- Data Source
  KAKENHI-PROJECT-23591259
[Book] ストレスの医学(吉川敏一監修)(CHAPTER 3, 生体の抗酸化システム(1)スーパーオキシドジスムターゼ系酸化)2008
- Author(s)
  鈴木敬一郎、藤原範子、大河原知水
- Publisher
  診断と治療社
- Data Source
  KAKENHI-PROJECT-20590320
[Book] 生体の抗酸化システム(1)スーパーオキシドジスムターゼ系. 酸化ストレスの医学, (吉川敏一監修)2008
- Author(s)
  鈴木敬一郎, 藤原範子, 大河原知水
- Publisher
  診断と治療社
- Data Source
  KAKENHI-PROJECT-19590605
[Book] Control of NO Production. Nitric Oxide Donors for Pharmaceutical and Biological Applications2005
- Author(s)
  Fujiwara, N.
- Total Pages
  27
- Publisher
  WILEY-VCH, Weinheim
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17500242
[Book] CHAPTER 3, 生体の抗酸化システム(1)スーパーオキシドジスムターゼ系、酸化ストレスの医学(吉川敏一監修)
- Author(s)
  鈴木敬一郎、藤原範子、大河原知水
- Publisher
  診断と治療社
- Data Source
  KAKENHI-PROJECT-19500313
[Journal Article] ChREBP deficiency prevents high sucrose diet-induced obesity through reducing sucrase expression2022
- Author(s)
  Sakiyama Haruhiko, Li Lan, Inoue Minako, Eguchi Hironobu, Yoshihara Daisaku, Fujiwara Noriko, Suzuki Keiichiro.
- Journal Title
  
  Journal of Clinical Biochemistry and Nutrition
  
  Volume: 71 Issue: 3 Pages: 221-228
- DOI
  10.3164/jcbn.22-15
- ISSN
  0912-0009, 1880-5086
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K11570
[Journal Article] Iron deficiency aggravates DMNQ-induced cytotoxicity via redox cycling in kidney-derived cells2022
- Author(s)
  Yoshihara Daisaku、Fujiwara Noriko、Eguchi Hironobu、Sakiyama Haruhiko、Suzuki Keiichiro
- Journal Title
  
  Free Radical Research
  
  Volume: 56 Issue: 7-8 Pages: 544-554
- DOI
  10.1080/10715762.2022.2154668
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K11478, KAKENHI-PROJECT-20K11570
[Journal Article] Activation of the mitogen-activated protein kinase ERK1/2 signaling pathway suppresses the expression of ChREBPα and β in HepG2 cells2021
- Author(s)
  Li L, Sakiyama H, Eguchi H, Yoshihara D, Fujiwara N, Suzuki K
- Journal Title
  
  FEBS Open Bio
  
  Volume: 11 Issue: 7 Pages: 2008-2018
- DOI
  10.1002/2211-5463.13208
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K11570
[Journal Article] A lack of ChREBP inhibits mitochondrial cristae formation in brown adipose tissue2021
- Author(s)
  Sakiyama H, Li L, Kuwahara-Otani S, Nakagawa T, Eguchi H, Yoshihara D, Shinohara M, Fujiwara N, Suzuki K.
- Journal Title
  
  Mol Cell Biochem
  
  Volume: 476 Issue: 10 Pages: 3577-3590
- DOI
  10.1007/s11010-021-04178-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K11570, KAKENHI-PROJECT-20K11628
[Journal Article] Cu/Zn-superoxide dismutase forms fibrillar hydrogels in a pH-dependent manner via a water-rich extended intermediate state2018
- Author(s)
  Fujiwara Noriko、Wagatsuma Michiru、Oba Naoto、Yoshihara Daisaku、Tokuda Eiichi、Sakiyama Haruhiko、Eguchi Hironobu、Ichihashi Motoko、Furukawa Yoshiaki、Inoue Tadashi、Suzuki Keiichiro
- Journal Title
  
  PLOS ONE
  
  Volume: 13 Issue: 10 Pages: e0205090-e0205090
- DOI
  10.1371/journal.pone.0205090
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-17H05705, KAKENHI-PUBLICLY-18H04564, KAKENHI-PROJECT-16H04768, KAKENHI-PROJECT-16K13060, KAKENHI-PROJECT-17K15077
[Journal Article] Caffeine-stimulated muscle IL-6 mediates alleviation of non-alcoholic fatty liver disease.2018
- Author(s)
  Fang C, Cai X, Hayashi S, Hao S, Sakiyama H, Wang X, Yang Q, Akira S, Nishiguchi S, Fujiwara N, Tsutsui H, Sheng J.
- Journal Title
  
  Biochim Biophys Acta Mol Cell Biol Lipids
  
  Volume: 1864 Issue: 3 Pages: 271-280
- DOI
  10.1016/j.bbalip.2018.12.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K01883
[Journal Article] 筋萎縮性側索硬化症に関与するCu,Zn-スーパーオキシドディスムターゼの研究2018
- Author(s)
  藤原範子
- Journal Title
  
  兵医大医会誌
  
  Volume: 42 Pages: 11-16
- Data Source
  KAKENHI-PROJECT-16K13060
[Journal Article] Cu,Zn-SOD deficiency induces the accumulation of hepatic collagen2016
- Author(s)
  Sakiyama H, Fujiwara N, Yoneoka Y, Yoshihara D, Eguchi H, Suzuki K
- Journal Title
  
  Free Radic Res
  
  Volume: 50 Issue: 6 Pages: 666-677
- DOI
  10.3109/10715762.2016.1164856
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K01736
[Journal Article] Solution oxygen-17 NMR application for observing a peroxidized cysteine residue in oxidized human SOD12016
- Author(s)
  Fujiwara N, Yoshihara D, Sakiyama H, Eguchi H, Suzuki K
- Journal Title
  
  Hyperfine Interact.
  
  Volume: 237 Issue: 1
- DOI
  10.1007/s10751-016-1320-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K13060
[Journal Article] The absence of the SOD1 gene causes abnormal monoaminergic neurotransmission and motivational impairment-like behavior in mice.2016
- Author(s)
  Daisaku Yoshihara, Noriko Fujiwara, Nobue Kitanaka, Junichi Kitanaka, Haruhiko Sakiyama, Hironobu Eguchi, Motohiko Takemura and Keiichiro Suzuki
- Journal Title
  
  Free Radical Research
  
  Volume: 50(11) Issue: 11 Pages: 1245-1256
- DOI
  10.1080/10715762.2016.1234048
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K16534, KAKENHI-PROJECT-15K01736, KAKENHI-PROJECT-16K13060
[Journal Article] Solution 17O-NMR approach for observing an oxidized cysteine residue in Cu,Zn-superoxide.2013
- Author(s)
  Hanashima S, Fujiwara N., Matsumoto K, Iwasaki N, Zheng G-Q, Torigoe H, Suzuki K, Taniguchi N, Yamaguchi Y.
- Journal Title
  
  Chem. Commun.
  
  Volume: 49 Issue: 14 Pages: 1449-1451
- DOI
  10.1039/c2cc36918d
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591259, KAKENHI-PROJECT-24500877
[Journal Article] Aberrant assembly of RNA-recognition motif 1 links to pathogenic conversion of TAR DNA-binding protein-43 (TDP-43)2013
- Author(s)
  Shodai A, Morimura T, Ido A, Uchida T, Ayaki T, Takahashi R, Kitazawa S, Suzuki S, Shirouzu M, Kigawa T, Muto Y, Yokoyama S, Takahashi R, Kitahara R, Ito H, Fujiwara N, Urushitani M
- Journal Title
  
  J Biol Chem
  
  Volume: 288(21) Issue: 21 Pages: 14886-14905
- DOI
  10.1074/jbc.m113.451849
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-23111001, KAKENHI-PLANNED-23111002, KAKENHI-PROJECT-23370080, KAKENHI-PROJECT-23390232, KAKENHI-PROJECT-23580417, KAKENHI-PROJECT-23591259, KAKENHI-PROJECT-24300132, KAKENHI-PROJECT-25840025
[Journal Article] Structural switching of Cu,Zn-superoxide dismutases at loop VI: insights from the crystal structure of 2-mercaptoethanol-modified enzyme.2012
- Author(s)
  Ihara K, Fujiwara N, Yamaguchi Y, Torigoe H, Wakatsuki S, Taniguchi N, Suzuki K.
- Journal Title
  
  Biosci Rep
  
  Volume: 32(6) Issue: 6 Pages: 539-48
- DOI
  10.1042/bsr20120029
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590563, KAKENHI-PROJECT-23591259, KAKENHI-PROJECT-24500877
[Journal Article] Alterations in renal iron metabolism caused by a copper/zinc-superoxide dismutase deficiency.2012
- Author(s)
  Yoshihara D, Fujiwara N, Kato S, Sakiyama H, Eguchi H, Suzuki K.
- Journal Title
  
  Free Radic Res
  
  Volume: 46(6) Issue: 6 Pages: 750-7
- DOI
  10.3109/10715762.2012.673223
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590563, KAKENHI-PROJECT-23591259, KAKENHI-PROJECT-24500420, KAKENHI-PROJECT-24500877
[Journal Article] Conserved Acidic Amino Acid Residues in a Second RNA Recognition Motif Regulate Assembly and Function of TDP-432012
- Author(s)
  Shodai A
- Journal Title
  
  PLoS ONE
  
  Volume: 7 Issue: 12 Pages: e52776-e52776
- DOI
  10.1371/journal.pone.0052776
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300131, KAKENHI-PROJECT-23580417, KAKENHI-PROJECT-23591259, KAKENHI-PROJECT-24300132, KAKENHI-PLANNED-23111002
[Journal Article] Oxidative Modification of Cysteine 111 Promotes Disulfide Bond-Independent Aggregation of SOD1.2012
- Author(s)
  Chen X., Shang H., Qiu X., Fujiwara N., Cui L., Li X-M., Gao T-M, Kong J.
- Journal Title
  
  Neurochem. Res.
  
  Volume: 37 Issue: 4 Pages: 835-845
- DOI
  10.1007/s11064-011-0679-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591259
[Journal Article] Cu,Zn-スーパーオキシドジスムターゼに関する研究2011
- Author(s)
  藤原範子
- Journal Title
  
  兵医大医会誌
  
  Volume: 第36巻1号 Pages: 59-65
- Data Source
  KAKENHI-PROJECT-23591259
[Journal Article] Hydrogen peroxide enhances LPS-induced nitric oxide production via the expression of interferon beta in BV-2 microglial cells.2011
- Author(s)
  Eguchi H, Fujiwara N, Sakiyama H, Yoshihara D, Suzuki K.
- Journal Title
  
  Neurosci Lett
  
  Volume: 494(1) Issue: 1 Pages: 29-33
- DOI
  10.1016/j.neulet.2011.02.047
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590563, KAKENHI-PROJECT-22790535, KAKENHI-PROJECT-23591259, KAKENHI-PROJECT-23700850
[Journal Article] Benefits and risks of antioxidants for health2010
- Author(s)
  Yoshihara D., Fujiwara N., Suzuki K.
- Journal Title
  
  Maturitas 67
  
  Pages: 375-376
- Data Source
  KAKENHI-PROJECT-20590320
[Journal Article] Induction of protective immunity by vaccination with wild-type apo SOD1 in the mutant SOD1 transgenic mice2010
- Author(s)
  Takeuchi S., Fujiwara N., Ido A., Ono M., Takeuchi Y., Tateno M., Suzuki K., Takahashi R., Tooyama I., Taniguchi N., Julien JP, Urushitani M.
- Journal Title
  
  J. Neuropathol. Exp. Neurol. 69
  
  Pages: 1044-1056
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590320
[Journal Article] The role of O-linked GlcNAc modification on the glucose response of ChREBP2010
- Author(s)
  Sakiyama H., Fujiwara N., Noguchi T., Eguchi H., Yoshihara D., Suzuki K.
- Journal Title
  
  Biochem. Biophys. Res. Commun. 402
  
  Pages: 784-789
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590320
[Journal Article] Antioxidants : benefits and risks for long-term health2010
- Author(s)
  Yoshihara D., Fujiwara N., Suzuki K.
- Journal Title
  
  Maturitas 67
  
  Pages: 103-107
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590320
[Journal Article] Protective role of glutathione S-transferase A4 induced in copper/zinc-superoxide dismutase knockout mice2009
- Author(s)
  Yoshihara D., Fujiwara N., Ookawara T., Kato S., Sakiyama H., Yokoe S., Eguchi H., Suzuki K
- Journal Title
  
  Free Radic. Biol. Med 47
  
  Pages: 559-567
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500313
[Journal Article] ALSにおける酸化ストレスおよび酸化型SODIの関与2009
- Author(s)
  藤原範子
- Journal Title
  
  実験医学(増刊) 27
  
  Pages: 140-144
- Data Source
  KAKENHI-PROJECT-19500313
[Journal Article] Protective role of glutathione S-transferase A4 induced in copper/zinc-superoxide dismutase knockout mice2009
- Author(s)
  Yoshihara D., Fujiwara N., Ookawara T., Kato S., Sakiyama H., Yokoe S., Eguchi H., Suzuki K.
- Journal Title
  
  Free Radic. Biol. Med. 47
  
  Pages: 559-567
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590320
[Journal Article] 酸化ストレスと健康2009
- Author(s)
  江口裕伸、藤原範子、大河原知水、鈴木敬一郎、谷口直之
- Journal Title
  
  生物資料分析 Vol.32,No.4
  
  Pages: 247-256
- NAID
  40019884015
- Data Source
  KAKENHI-PROJECT-19500313
[Journal Article] ALSにおける酸化ストレスおよび酸化型SOD1の関与2009
- Author(s)
  藤原範子
- Journal Title
  
  実験医学(増刊) 27
  
  Pages: 140-144
- Data Source
  KAKENHI-PROJECT-20590320
[Journal Article] 酸化ストレスと健康、2009
- Author(s)
  江口裕伸、藤原範子、大河原知水、鈴木敬一郎、谷口直之
- Journal Title
  
  生物資料分析 Vol.32, No.4
  
  Pages: 247-256
- NAID
  40019884015
- Data Source
  KAKENHI-PROJECT-20590320
[Journal Article] ALSにおける酸化ストレスおよび酸化型SOD1の関与、実験医学(増刊)2009
- Author(s)
  藤原範子、松本紋子、鈴木敬一郎、谷口直之
- Journal Title
  
  病態解明に迫る活性酸素シグナルと酸化ストレス(谷口直之監修)(羊土社) Vol.27, No.15
  
  Pages: 140-144
- Data Source
  KAKENHI-PROJECT-20590320
[Journal Article] ALSにおける酸化ストレスおよび酸化型SOD1の関与2009
- Author(s)
  藤原範子、松本紋子、鈴木敬一郎、谷口直之
- Journal Title
  
  病態解明に迫る活性酸素シグナルと酸化ストレス(谷口直之監修)(羊土社) Vol.27,No.15
  
  Pages: 140-144
- Data Source
  KAKENHI-PROJECT-19500313
[Journal Article] MEDICAL TOPICS第28回、ヒトCu,Zn-SOD (SOD1)のシステイン残基の酸化的修飾とその特異抗体の開発2008
- Author(s)
  藤原範子
- Journal Title
  
  THE LUNG perspectives(メディカルレビュー社) Vol.16, No.3
  
  Pages: 90-95
- Data Source
  KAKENHI-PROJECT-20590320
[Journal Article] ヒトCu, Zn-SOD (SOD1)のシステイン残基の酸化的修飾とその特異抗体の開発2008
- Author(s)
  藤原範子
- Journal Title
  
  THE LUNG perspectives(メディカルレビュー) Vol.16,No.3
  
  Pages: 90-95
- Data Source
  KAKENHI-PROJECT-19500313
[Journal Article] Oxidative modification to cysteine sulfonic acid of Cys111 in human copper-zinc superoxide dismutase2007
- Author(s)
  Fujiwara, N.
- Journal Title
  
  J.Biol.Chem 282
  
  Pages: 35933-35944
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500313
[Journal Article] Oxidative modification to cysteine sulfonic Acid of cys111 in human copper-zinc superoxide dismutase2007
- Author(s)
  Fujiwara N., Nakano M, Kato S, Yoshihara D, Ookawara T, Eguchi H, Taniguchi N, Suzuki K
- Journal Title
  
  J. Biol. Chem 282
  
  Pages: 35933-35944
- NAID
  120006782320
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500313
[Journal Article] Oxidative modification to cysteine sulfonic acid of Cys111 in human copper-zinc superoxide dismutase2007
- Author(s)
  Fujiwara N., et. al.
- Journal Title
  
  J.Biol.Chem 282
  
  Pages: 35933-35944
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590605
[Journal Article] Oxidative modification to Cysteine sulfonic acid of cys111 in human copper-zinc superoxide dismutase2007
- Author(s)
  Fujiwara, N.
- Journal Title
  
  J.Biol.Chem. 282
  
  Pages: 35933-35944
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590305
[Journal Article] Oxidative modification to cysteine sulfonic acid of Cyslll in human copper-zinc superoxide dismutase2007
- Author(s)
  Fujiwara, N
- Journal Title
  
  J.Biol.Chem 282
  
  Pages: 35933-35944
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590305
[Journal Article] Oxidative modification to Cysteine sulfomc acid of cysill in human copper-zinc superoxide dismutase2006
- Author(s)
  Fujiwara. N.
- Journal Title
  
  J. Biol. Chem. 282
  
  Pages: 35933-35944
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590305
[Journal Article] Effects of copper metabolism on neurological functions in Wistar and Wilson's disease model rats.2006
- Author(s)
  Fujiwara N.
- Journal Title
  
  Biochem. Biophys. Res. Commun. 349・3
  
  Pages: 1079-1086
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17500242
[Journal Article] Effects of copper metabolism on neurological functions in Wistar and Wilson's disease model rats.2006
- Author(s)
  Fujiwara, N.
- Journal Title
  
  Biochem. Biophys. Res. Commun. 349
  
  Pages: 1079-1086
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590305
[Journal Article] Effects of copper metabolism on neurological functions in Wistar and Wilson's disease model rats.2006
- Author(s)
  Fujiwara, N.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 349・3
  
  Pages: 1079-1086
- Data Source
  KAKENHI-PROJECT-18590305
[Journal Article] Effects of copper metabolism on neurological functions in Wistar and Wilson's disease model rats.2006
- Author(s)
  Fujiwara, N.
- Journal Title
  
  Biochem Biophys Res Coommun. 349. 3
  
  Pages: 1079-1086
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17500242
[Journal Article] Effects of copper metabolism on neurological functions in Wistar and Wilson's disease model rats2006
- Author(s)
  Fujiwara, N.
- Journal Title
  
  Biochem.Biophys.Res.Commun 349
  
  Pages: 1079-1086
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590305
[Journal Article] Effects of copper metabolism on neurological functions in Wistar and Wilson's disease model rats.2006
- Author(s)
  Fujiwara N.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 349・3
  
  Pages: 1079-1086
- Data Source
  KAKENHI-PROJECT-17500242
[Journal Article] Different immunoreactivity against monoclonal antibodies between wild-type and mutant copper/zinc superoxide dismutase linked to amyotrophic lateral sclerosis.2005
- Author(s)
  Fujiwara, N.
- Journal Title
  
  J. Biol. Chem. 28・6
  
  Pages: 5061-5070
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17500242
[Journal Article] Different immunoreactivity against monoclonal antibodies between wild-type and mutant copper/zinc superoxide dismutase linked to amyotrophic lateral sclerosis.2005
- Author(s)
  Fujiwara, N.
- Journal Title
  
  J Biol Chem. 280.6
  
  Pages: 5061-70
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17500242
[Journal Article] Different immunoreactivity against monoclonal antibodies between wild-type and mutant copper/zinc superoxide dismutase linked to amyotrophic lateral sclerosis.2005
- Author(s)
  Fujiwara, N.
- Journal Title
  
  J Biol Chem. 280.6
  
  Pages: 5061-5070
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590258
[Journal Article] Different immunoreactivity against monoclonal antibodies between wild-type and mutant copper/zinc superoxide dismutase linked to amyotrophic lateral sclerosis.2005
- Author(s)
  Fujiwara, N.
- Journal Title
  
  J Biol Chem. 28・6
  
  Pages: 5061-5070
- Data Source
  KAKENHI-PROJECT-17500242
[Journal Article] Different immunoreactivity against monoclonal antibodies between wild-type and mutant copper/zinc superoxide dismutase linked to amyotrophic lateral sclerosis.2005
- Author(s)
  Fujiwara, N.
- Journal Title
  
  J Biol Chem 280・6
  
  Pages: 5061-70
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590258
[Patent] TDP-43の凝集体が蓄積する疾患を治療及び/又は予防するための化合物のスクリーニング方法2013
- Inventor(s)
  漆谷真、藤原範子、北原亮、伊東秀文
- Industrial Property Rights Holder
  漆谷真、藤原範子、北原亮、伊東秀文
- Industrial Property Rights Type
  特許
- Filing Date
  2013-03-08
- Overseas
- Data Source
  KAKENHI-PROJECT-23591259
[Patent] TTDP-43の凝集体が蓄積する疾患を治療及び／又は予防するための化合物のスクリーニング方法2013
- Inventor(s)
  漆谷真、藤原範子、北原亮、伊東秀文
- Industrial Property Rights Holder
  漆谷真、藤原範子、北原亮、伊東秀文
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2013-046451
- Filing Date
  2013-03-08
- Data Source
  KAKENHI-PROJECT-23591259
[Patent] TDP-43の凝集体が蓄積する疾患の発症リスクを予測する方法、診断薬及び治療薬2012
- Inventor(s)
  漆谷真、藤原範子、伊東秀文
- Industrial Property Rights Holder
  漆谷真、藤原範子、伊東秀文
- Industrial Property Rights Type
  特許
- Filing Date
  2012-02-13
- Overseas
- Data Source
  KAKENHI-PROJECT-23591259
[Presentation] スーパーオキシドディスムターゼ1の野生型とG93A変異体の分子の揺らぎの違いに関する分子動力学的研究2024
- Author(s)
  福島和明、藤原範子
- Organizer
  日本化学会第104春季年会
- Data Source
  KAKENHI-PROJECT-22K11870
[Presentation] ALS原因タンパク質であるSOD1のアミロイドゲルの研究から細胞内凝集の研究へ2023
- Author(s)
  藤原範子
- Organizer
  第14回タンパク質の異常凝集とその防御・修復機構に関する研究会
- Invited
- Data Source
  KAKENHI-PROJECT-22K11870
[Presentation] 家族性ALS原因タンパク質であるSOD1の細胞内凝集に寄与するアミノ酸残基の同定2023
- Author(s)
  浅井新喜, 矢埜杏果, 東野智行, 吉原大作, 江口裕伸, 鈴木敬一郎, 藤原範子
- Organizer
  第69回日本生化学会近畿支部例会
- Data Source
  KAKENHI-PROJECT-22K11870
[Presentation] 家族性ALSを引き起こす変異SOD1の凝集体形成に寄与するIle352023
- Author(s)
  矢埜杏果, 浅井新喜, 東野智行, 吉原大作, 江口裕伸, 崎山晴彦, 鈴木敬一郎, 藤原範子
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-22K11870
[Presentation] 家族性ALS原因タンパク質SOD1のアミロイド化配列と凝集体形成配列の比較2023
- Author(s)
  矢埜杏果，浅井新喜，東野智行，吉原大作，江口裕伸，崎山晴彦，鈴木敬一郎，藤原範子
- Organizer
  第69回日本生化学会近畿支部例会
- Data Source
  KAKENHI-PROJECT-22K11870
[Presentation] 家族性ALSの原因となるSOD1の細胞内凝集コア配列とアミロイドコア配列の比較検討2023
- Author(s)
  矢埜杏果、浅井新喜、東野智行、吉原大作、江口裕伸、崎山晴彦、鈴木敬一郎、藤原範子
- Organizer
  第46回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-22K11870
[Presentation] 家族性ALSを引き起こすSOD1の細胞内凝集におけるIle35の重要性2023
- Author(s)
  浅井新喜、矢埜杏果、東野智行、吉原大作、江口裕伸、崎山晴彦、鈴木敬一郎、藤原範子
- Organizer
  第46回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-22K11870
[Presentation] Effects of peroxynitrite on the fucosylation and phosphorylation of c-Met in HepG2 cells2022
- Author(s)
  Eguchi Hironobu, Hamazaki Shigeaki, Sakiyama Haruhiko, Yoshihara Daisaku, Fujiwara Noriko, Suzuki Keiichiro
- Organizer
  The 22nd Annual Scientific Meeting of the Nitric Oxide Society of Japan
- Data Source
  KAKENHI-PROJECT-20K11570
[Presentation] ALS原因タンパク質であるSOD1の凝集体形成に必要なアミノ酸配列の同定2022
- Author(s)
  東野智行, 浅井新喜, 矢埜杏果, 吉原大作, 江口裕伸, 崎山晴彦, 藤原範子, 鈴木敬一郎
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-22K11870
[Presentation] SOD1欠損マウスにおける脳内モノアミン代謝の変化と行動異常2022
- Author(s)
  吉原大作、藤原範子、北中順惠、北中純一、崎山晴彦、江口裕伸、竹村基彦、鈴木敬一郎
- Organizer
  第75回日本酸化ストレス学会学術集会
- Data Source
  KAKENHI-PROJECT-20K11478
[Presentation] Comparison of the sequences required for intracellular aggregation and amyloid formation of SOD1 causing familial ALS2022
- Author(s)
  Kyoka Yano, Tomoyuki Higashino, Yoshiyuki Asai, Daisaku Yoshihara, Hironobu Eguchi, Haruhiko Sakiyama, Noriko Fujiwara, Keiichiro Suzuki
- Organizer
  Asian Pacific Prion Symposium 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K11870
[Presentation] 鉄欠乏状態はキノンの細胞毒性を増強させる2022
- Author(s)
  吉原大作, 藤原範子, 江口裕伸, 崎山晴彦, 鈴木敬一郎
- Organizer
  第46回日本鉄バイオサイエンス学会学術集会
- Data Source
  KAKENHI-PROJECT-20K11570
[Presentation] 鉄欠乏はRedox cycling quinoneによるROS産生と細胞障害性を増大させる2022
- Author(s)
  吉原大作, 藤原範子, 江口裕伸, 崎山晴彦, 鈴木敬一郎
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-20K11570
[Presentation] ALS原因タンパク質であるSOD1の凝集体形成に必要なアミノ酸配列の同定2022
- Author(s)
  東野智行, 浅井新喜, 矢埜杏果, 吉原大作, 江口裕伸, 崎山晴彦, 藤原範子, 鈴木敬一郎
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-20K11570
[Presentation] 転写因子ChREBPのミトコンドリアのクリステ形成における役割2021
- Author(s)
  崎山晴彦、Li Lan、江口裕伸、吉原大作、藤原範子、鈴木敬一郎
- Organizer
  第94回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-20K11570
[Presentation] 転写因子ChREBPは褐色脂肪組織でカルジオリピン合成に関与する2021
- Author(s)
  崎山晴彦、Li Lan、江口裕伸、吉原大作、藤原範子、鈴木敬一郎
- Organizer
  第74回日本酸化ストレス学会学術集会
- Data Source
  KAKENHI-PROJECT-20K11570
[Presentation] 鉄欠乏状態におけるRedox cycling quinone: DMNQによる細胞傷害2021
- Author(s)
  吉原大作、藤原範子、江口裕伸、崎山晴彦、鈴木敬一郎
- Organizer
  第74回日本酸化ストレス学会　第21回日本NO学会合同学術集会
- Data Source
  KAKENHI-PROJECT-20K11478
[Presentation] 転写因子ChREBPの脂肪組織におけるあらたな役割2020
- Author(s)
  崎山晴彦、Li Ran、中川勉、江口裕伸、吉原大作、藤原範子、鈴木敬一郎
- Organizer
  日本生化学会
- Data Source
  KAKENHI-PROJECT-20K11570
[Presentation] 転写因子ChREBPの脂肪組織におけるあらたな役割2020
- Author(s)
  崎山晴彦、Li Ran、中川勉、江口裕伸、吉原大作、藤原範子、鈴木敬一郎
- Organizer
  日本生化学会
- Data Source
  KAKENHI-PROJECT-18K11147
[Presentation] Abnormal monoaminergic neurotransmission and motivational impairment-like behavior in SOD1 knockout (KO) mice2019
- Author(s)
  Daisaku Yoshihara, Noriko Fujiwara, Nobue Kitanaka, Junichi Kitanaka, Haruhiko Sakiyama, Hironobu Eguchi, Motohiko Takemura and Keiichiro Suzuki
- Organizer
  The 9th Biennial Meeting of Society for Free Radical Research-Asia (SFRR-Asia)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08400
[Presentation] ChREBP-KOマウスの褐色脂肪組織における脂質代謝と熱産生に関する研究2019
- Author(s)
  Li Ran、崎山晴彦、中川勉、江口裕伸、吉原大作、藤原範子、鈴木敬一郎
- Organizer
  日本分子生物学会
- Data Source
  KAKENHI-PROJECT-18K11147
[Presentation] ChREBP-KOマウスの褐色脂肪組織における脂質代謝と熱産生に関する研究2019
- Author(s)
  Li Ran、崎山晴彦、中川勉、江口裕伸、吉原大作、藤原範子、鈴木敬一郎
- Organizer
  日本分子生物学会
- Data Source
  KAKENHI-PROJECT-17K01883
[Presentation] 細胞内レドックス環境の変化が鉄動態に与える影響2019
- Author(s)
  吉原大作、藤原範子、平山祐、丹羽正人、江口裕伸、崎山晴彦、永澤秀子、鈴木敬一郎
- Organizer
  第72回日本酸化ストレス学会学術集会
- Data Source
  KAKENHI-PROJECT-17K08400
[Presentation] 転写因子ChREBP阻害による抗肥満効果のメカニズムの検討2019
- Author(s)
  崎山晴彦、Li Ran、中川勉、江口裕伸、吉原大作、藤原範子、鈴木敬一郎.
- Organizer
  日本生化学会
- Data Source
  KAKENHI-PROJECT-17K01883
[Presentation] 転写因子ChREBP欠損マウスにおける抗肥満効果に関する研究2019
- Author(s)
  崎山晴彦、Li Ran、中川勉、江口裕伸、吉原大作、藤原範子、鈴木敬一郎
- Organizer
  日本酸化ストレス学会
- Data Source
  KAKENHI-PROJECT-18K11147
[Presentation] スーパーオキシド産生剤DMNQによる細胞内の鉄動態の変化2019
- Author(s)
  吉原大作、藤原範子、平山祐、丹羽正人、江口裕伸、崎山晴彦、永澤秀子、鈴木敬一郎
- Organizer
  第43回日本鉄バイオサイエンス学会学術集会
- Data Source
  KAKENHI-PROJECT-17K08400
[Presentation] 転写因子ChREBP阻害による抗肥満効果のメカニズムの検討2019
- Author(s)
  崎山晴彦、Li Ran、中川勉、江口裕伸、吉原大作、藤原範子、鈴木敬一郎
- Organizer
  日本生化学会
- Data Source
  KAKENHI-PROJECT-18K11147
[Presentation] 転写因子ChREBP欠損マウスにおける抗肥満効果に関する研究2019
- Author(s)
  崎山晴彦、Li Ran、中川勉、江口裕伸、吉原大作、藤原範子、鈴木敬一郎
- Organizer
  日本酸化ストレス学会
- Data Source
  KAKENHI-PROJECT-17K01883
[Presentation] 酸化ストレスが鉄代謝異常を引き起こす機序の解析2018
- Author(s)
  吉原大作、藤原範子、平山祐、丹羽正人、江口裕伸、崎山晴彦、永澤秀子、鈴木敬一郎
- Organizer
  第42回日本鉄バイオサイエンス学会学術集会
- Data Source
  KAKENHI-PROJECT-17K08400
[Presentation] ChREBP欠損マウスが有する抗肥満作用の検討2018
- Author(s)
  井上美奈子、崎山晴彦、江口裕伸、吉原大作、藤原範子、鈴木敬一郎
- Organizer
  第65回日本生化学会　近畿支部例会
- Data Source
  KAKENHI-PROJECT-18K11147
[Presentation] ALS原因タンパク質であるSOD1の変性と凝集2018
- Author(s)
  藤原範子
- Organizer
  第18回日本蛋白質科学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-16K13060
[Presentation] 転写因子ChREBP欠損マウスにおける抗肥満効果の解明2018
- Author(s)
  崎山晴彦、Li Ran、中川勉、江口裕伸、吉原大作、藤原範子、鈴木敬一郎
- Organizer
  第28回日本メイラード学会年会
- Data Source
  KAKENHI-PROJECT-17K01883
[Presentation] 転写因子ChREBP欠損マウスにおける抗肥満効果に関する研究2018
- Author(s)
  崎山晴彦、Li Ran、中川勉、江口裕伸、吉原大作、藤原範子、鈴木敬一郎
- Organizer
  第28回　日本メイラード学会年会
- Data Source
  KAKENHI-PROJECT-18K11147
[Presentation] Appropriate water-rich elongated intermediate is required for fibrillation and hydrogellation of ALS-causative SOD12018
- Author(s)
  Noriko Fujiwara, Michiru Wagatsuma, Naoto Oba, Daisaku Yoshihara, Eiichi Tokuda, Hironobu Eguchi, Haruhiko Sakiyama, Tadashi Inoue, Yoshiaki Furukawa, Keiichiro Suzuki
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-16K13060
[Presentation] ChREBP欠損マウスが有する抗肥満作用の検討2018
- Author(s)
  崎山晴彦、中川勉、江口裕伸、吉原大作、藤原範子、鈴木敬一郎
- Organizer
  第91回　日本生化学会大会
- Data Source
  KAKENHI-PROJECT-17K01883
[Presentation] ChREBP欠損マウスが有する抗肥満作用の検討2018
- Author(s)
  崎山晴彦、中川勉、井上美奈子、江口裕伸、吉原大作、藤原範子、鈴木敬一郎
- Organizer
  第91回　日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18K11147
[Presentation] ChREBP欠損マウスが有する抗肥満作用の検討2018
- Author(s)
  井上美奈子、崎山晴彦、江口裕伸、吉原大作、藤原範子、鈴木敬一郎
- Organizer
  第65回日本生化学会　近畿支部例会
- Data Source
  KAKENHI-PROJECT-17K01883
[Presentation] Wild-type SOD1 is misfolded in cerebrospinal fluid of sporadic ALS2018
- Author(s)
  Yoshiaki Furukawa, Eiichi Tokuda, Shinji Ohara, Noriko Fujiwara
- Organizer
  29th International symposium on ALS/MND
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K13060
[Presentation] 酸化ストレスによる鉄代謝の変化と細胞死の誘導2018
- Author(s)
  吉原大作、藤原範子、平山祐、丹羽正人、江口裕伸、崎山晴彦、永澤秀子、鈴木敬一郎
- Organizer
  第71回日本酸化ストレス学会　第18回日本NO学会　合同学術集会
- Data Source
  KAKENHI-PROJECT-17K08400
[Presentation] Cu/Zn-Superoxide Dismutase Forms hydrogels composed of amyloid fibrils in a pH-Dependent Manner2018
- Author(s)
  Noriko Fujiwara, Michiru Wagatsuma, Naoto Oba, Daisaku Yoshihara, Eiichi Tokuda, Haruhiko Sakiyama, Hironobu Eguchi, Motoko Ichihashi, Yoshiaki Furukawa, Tadashi Inoue, Keiichiro Suzuki
- Organizer
  APPS2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K13060
[Presentation] 転写因子ChREBP欠損マウスにおける抗肥満効果の解明2017
- Author(s)
  崎山晴彦、中川勉、江口裕伸、吉原大作、藤原範子、鈴木敬一郎
- Organizer
  第90回日本生化学会
- Data Source
  KAKENHI-PROJECT-17K01883
[Presentation] 転写因子ChREBP欠損マウスにおけるフルクトース代謝の解析2017
- Author(s)
  崎山晴彦、井上美奈子、江口裕伸、藤原範子、吉原大作、鈴木敬一郎
- Organizer
  第27回日本メイラード学会
- Data Source
  KAKENHI-PROJECT-17K01883
[Presentation] ALS原因タンパク質であるSOD1の変性と凝集2017
- Author(s)
  藤原範子
- Organizer
  第11回QCM研究会
- Invited
- Data Source
  KAKENHI-PROJECT-16K13060
[Presentation] 酸化ストレスによる細胞死の誘導と鉄イオン動態の変化2017
- Author(s)
  吉原大作、藤原範子、平山祐、丹羽正人、江口裕伸、崎山晴彦、永澤秀子、鈴木敬一郎
- Organizer
  第41回日本鉄バイオサイエンス学会学術集会
- Data Source
  KAKENHI-PROJECT-17K08400
[Presentation] 酸化ストレスが細胞内の鉄イオン動態に与える影響2017
- Author(s)
  吉原大作、藤原範子、平山祐、丹羽正人、江口裕伸、崎山晴彦、永澤秀子、鈴木敬一郎
- Organizer
  生命科学系学会合同年次集会（第90回日本生化学会大会）
- Data Source
  KAKENHI-PROJECT-17K08400
[Presentation] 転写因子ChREBP欠損マウスにおけるフルクトース代謝の解析2017
- Author(s)
  崎山　晴彦、中川　勉、井上　美奈子、江口　裕伸、吉原　大作、藤原　範子、鈴木　敬一郎
- Organizer
  第27回日本メイラード学会
- Data Source
  KAKENHI-PROJECT-15K01736
[Presentation] ALS原因タンパク質であるSOD1の線維ゲル形成とその物性2017
- Author(s)
  藤原範子、我妻美千留、大場矢登、吉原大作、徳田栄一、江口裕伸、崎山晴彦、井上正志、古川良明、鈴木敬一郎
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-16K13060
[Presentation] 転写因子ChREBP欠損マウスにおける抗肥満効果の解明2017
- Author(s)
  崎山晴彦、井上美奈子、中川勉、江口裕伸、吉原大作、藤原範子、鈴木敬一郎
- Organizer
  第90回日本生化学会
- Data Source
  KAKENHI-PROJECT-15K01736
[Presentation] Lacking SOD1 gene causes motivational impairment-like behaviors2016
- Author(s)
  Fujiwara Noriko, Yoshihara Daisaku, Sakiyama Haruhiko, Eguchi Hironobu, Suzuki Keiichiro
- Organizer
  NO2016
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2016-05-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K13060
[Presentation] Solution oxygen17-NMR application for observing a peroxidized cysteine residue in oxidized copper/zinc-superoxide dismutase2016
- Author(s)
  Fujiwara Noriko, Yoshihara Daisaku, Sakiyama Haruhiko, Eguchi Hironobu, Suzuki Keiichiro
- Organizer
  Huperfine2016
- Place of Presentation
  Leuven
- Year and Date
  2016-07-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K13060
[Presentation] The study of liver fiborisis in SOD1 knockout mice2016
- Author(s)
  H Sakiyama, H Eguchi, N Fujiwara, D Yoshihara, K Suzuki
- Organizer
  第9回　国際NO学会
- Place of Presentation
  仙台国際センター（宮城県　仙台市）
- Year and Date
  2016-05-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K01736
[Presentation] SOD1欠損はモチベーション低下を引き起こす2016
- Author(s)
  吉原大作, 藤原範子, 崎山晴彦, 江口裕伸, 鈴木敬一郎
- Organizer
  第69回日本酸化ストレス学会学術集会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2016-08-30
- Data Source
  KAKENHI-PROJECT-16K13060
[Presentation] 酸化ストレスがChREBP活性化に与える影響の検討2016
- Author(s)
  崎山晴彦、井上美奈子、江口裕伸、藤原範子、吉原大作、鈴木敬一郎
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台国際センター（宮城県　仙台市）
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-15K01736
[Presentation] 糖化修飾がSOD1欠損による肝繊維化へ及ぼす影響2016
- Author(s)
  崎山晴彦、江口裕伸、藤原範子、吉原大作、鈴木敬一郎
- Organizer
  第26回日本メイラード学会
- Place of Presentation
  つくば国際会議場（茨城県　つくば市）
- Year and Date
  2016-11-11
- Data Source
  KAKENHI-PROJECT-15K01736
[Presentation] Involvement of the Maillard reaction product of liver fibrosis by oxidative stress2015
- Author(s)
  Haruhiko Sakiyama, Hironobu Eguchi, Noriko Fujiwara, Daisaku Yoshihara, and Keiichiro Suzuki
- Organizer
  第12回国際メイラード反応シンポジウム
- Place of Presentation
  ITO International Research Center（東京都）
- Year and Date
  2015-09-01
- Data Source
  KAKENHI-PROJECT-15K01736
[Presentation] SOD1 KOマウスの肝臓におけるコラーゲン蓄積の検討2015
- Author(s)
  崎山晴彦、米岡由佳、藤原範子、江口裕伸、吉原大作、鈴木敬一郎
- Organizer
  第88回日本生化学会大会
- Place of Presentation
  神戸国際会議場(兵庫県、神戸市)
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25350911
[Presentation] Involvement of the Maillard reaction product of liver fibrosis by oxidative stress2015
- Author(s)
  Haruhiko Sakiyama, Hironobu Eguchi, Noriko Fujiwara, Daisaku Yoshihara, and Keiichiro Suzuki
- Organizer
  第12回国際メイラード反応シンポジウム
- Place of Presentation
  ITO international Research Center(東京都)
- Year and Date
  2015-09-01
- Data Source
  KAKENHI-PROJECT-25350911
[Presentation] SOD1 KOマウスの肝臓におけるコラーゲン蓄積の検討2015
- Author(s)
  崎山晴彦、米岡由佳、藤原範子、江口裕伸、吉原大作、鈴木敬一郎
- Organizer
  第88回日本生化学会大会
- Place of Presentation
  神戸国際会議場（兵庫県、神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K01736
[Presentation] 酸化ストレスと転写因子Carbohydrate Response Element-binding Protein (ChREBP)の活性化について2015
- Author(s)
  崎山晴彦、江口裕伸、吉原大作、米岡由佳、藤原範子、鈴木敬一郎
- Organizer
  第15回日本NO学会学術集会
- Place of Presentation
  千里ライフサイエンスセンター（大阪府、豊中市）
- Year and Date
  2015-06-26
- Data Source
  KAKENHI-PROJECT-15K01736
[Presentation] 酸化ストレスと転写因子Carbohydrate Response Element-binding Protein (ChREBP)の活性化について2015
- Author(s)
  崎山晴彦、江口裕伸、吉原大作、米岡由佳、藤原範子、鈴木敬一郎
- Organizer
  第15回日本NO学会学術集会
- Place of Presentation
  千里ライフサイエンスセンター(大阪府、豊中市)
- Year and Date
  2015-06-26
- Data Source
  KAKENHI-PROJECT-25350911
[Presentation] Immunotherapy targeting loop VI in Cu,Zn-superoxide dismutase exacerbates ALS pathogenesis2014
- Author(s)
  Fujiwara Noriko, Urushitani Makoto, Yoshihara Daisaku, Morimura Toshifumi Sakiyama Haruhiko, Eguchi Hironobu, Suzuki Keiichiro
- Organizer
  SFRRI2014
- Place of Presentation
  Kyoto
- Year and Date
  2014-03-24
- Data Source
  KAKENHI-PROJECT-23591259
[Presentation] Immunotherapy targeting loop VI in Cu,Zn-superoxide dismutase exacerbates ALS pathogenesis2014
- Author(s)
  Fujiwara Noriko, Urushitani Makoto, Yoshihara Daisaku, Morimura Toshifumi Sakiyama Haruhiko, Eguchi Hironobu, Suzuki Keiichiro
- Organizer
  SFRRI 2014
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-23591259
[Presentation] SODlの酸化修飾および構造解析---ALS病態への関与---2013
- Author(s)
  藤原範子
- Organizer
  レドックス・ライフイノベーション第l70委員会、第6回夏の委員会
- Place of Presentation
  弘前
- Year and Date
  2013-08-23
- Data Source
  KAKENHI-PROJECT-23591259
[Presentation] SOD1 KO マウスの肝臓における糖および脂質代謝の検討2013
- Author(s)
  米岡由佳, 崎山晴彦, 藤原範子, 江口裕伸, 吉原大作, 鈴木敬一郎
- Organizer
  第60回生化学会近畿支部例会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-25350911
[Presentation] SOD1 KOマウスの肝臓における糖および脂質代謝の検討2013
- Author(s)
  崎山晴彦, 江口裕伸, 吉原大作, 米岡由佳, 藤原範子, 鈴木敬一郎
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-25350911
[Presentation] 酸素NMRによる酸化型SODlの新規検出方法2013
- Author(s)
  藤原範子、花島慎弥、山口芳樹、鄭国慶、鳥越秀峰、谷口直之、鈴木敬一郎
- Organizer
  第66回日本酸化ストレス学会学術集会
- Place of Presentation
  名古屋
- Year and Date
  2013-06-13
- Data Source
  KAKENHI-PROJECT-23591259
[Presentation] 糖化と酸化ストレスによる脂質代謝異常2013
- Author(s)
  米岡由佳, 崎山晴彦, 藤原範子, 江口裕伸, 吉原大作, 鈴木敬一郎
- Organizer
  第23回　日本メイラード学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-25350911
[Presentation] ヒトSOD1二量体のループVIは非対称構造を有する2012
- Author(s)
  藤原範子、伊原健太郎、山口芳樹、若槻壮市、谷口直之、鈴木敬一郎
- Organizer
  第65回日本酸化ストレス学会学術集会
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-23591259
[Presentation] TWO FORMS OF LOOP VI INCLUDING REACTIVE CYS111 OF HUMAN COPPER-ZINC SUPEROXIDE DISMUTASE2012
- Author(s)
  Fujiwara N, Ihara K, Kato S, Yoshihara D, Eguchi H, Sakiyama H, Suzuki K
- Organizer
  13th International Congress of Biochemistry and Molecular biology 2012 (FAOBMB CONGRESS)
- Place of Presentation
  Bankok, Thailand
- Data Source
  KAKENHI-PROJECT-23591259
[Presentation] TWO FORMS OF LOOP VI INCLUDING REACTIVE CYS111 OF HUMAN COPPER-ZINC SUPEROXIDE DISMUTASE2012
- Author(s)
  Fujiwara N, Ihara K, Kato S, Yoshihara D, Eguchi H, Sakiyama H, Suzuki K.
- Organizer
  13th International Congress of Biochemistry and Molecular biology 2012 (FAOBMB CONGRESS)
- Place of Presentation
  Bankok, Thailand
- Data Source
  KAKENHI-PROJECT-24500877
[Presentation] Cu/Zn-スーパーオキシドジスムターゼのループVI構造は2種類のタイプに分類される2012
- Author(s)
  藤原範子、伊原健太郎、山口芳樹、鳥越秀峰、若槻壮市、谷口直之、鈴木敬一郎
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23591259
[Presentation] Cu/Zn-スーパーオキシドジスムターゼのループVI構造は２種類のタイプに分類される2012
- Author(s)
  藤原範子、伊原健太郎、山口芳樹、鳥越秀峰、若槻壮市、谷口直之、鈴木敬一郎
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23591259
[Presentation] 変異型SODlに対する新規モノクローナル抗体の反応性2012
- Author(s)
  野口隆弘,藤原範子,鴨田信子,北野隆之,武内悠希,吉原大作,崎山晴彦,江口裕伸,鈴木敬一郎
- Organizer
  第59回日本生化学会近畿支部例会
- Place of Presentation
  京都
- Year and Date
  2012-05-19
- Data Source
  KAKENHI-PROJECT-23591259
[Presentation] TWO FORMS OF LOOP VI INCLUDING REACTIVE CYS^<11>1 OF HUMAN COPPER-ZINC SUPEROXIDE DISMUTASE2012
- Author(s)
  Fujiwara N, Ihara K, Kato S, Yoshihara D, Eguchi H, Sakiyama H, Suzuki K
- Organizer
  13th International Congress of Biochemistry and Molecular biology 2012 (FAOBMB CONGRESS)
- Place of Presentation
  Bankok, Thailand
- Data Source
  KAKENHI-PROJECT-23591259
[Presentation] SOD1欠損が腎臓の鉄代謝に与える影響2012
- Author(s)
  吉原大作，藤原範子，加藤信介，崎山晴彦，江口裕伸，鈴木敬一郎
- Organizer
  第65回日本酸化ストレス学会学術集会
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-24500877
[Presentation] 変異型SOD1に対する新規モノクローナル抗体の反応性2012
- Author(s)
  野口隆弘，藤原範子，鴨田信子，北野隆之，武内悠希，吉原大作，崎山晴彦，江口裕伸，鈴木敬一郎
- Organizer
  第59回日本生化学会近畿支部例会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24500877
[Presentation] 変異型SOD1に対する新規モノクローナル抗体の反応性2012
- Author(s)
  野口隆弘，藤原範子，鴨田信子，北野隆之，武内悠希，吉原大作，崎山晴彦，江口裕伸，鈴木敬一郎
- Organizer
  第59回日本生化学会近畿支部例会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23591259
[Presentation] 細胞増殖活性を指標とした抗体選択法2012
- Author(s)
  寺西佑理、河原正浩、藤原範子、上田宏、鈴木敬一郎、長棟輝行
- Organizer
  化学工学会第77年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23591259
[Presentation] ヒトSOD1二量体のループVIは非対称構造を有する2012
- Author(s)
  藤原範子、伊原健太郎、山口芳樹、若槻壮市、谷口直之、鈴木敬一郎
- Organizer
  第65回日本酸化ストレス学会学術集会
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-24500877
[Presentation] Oxidation of Cys111 residue in loop VI of human copper/zinc superoxide dismutase2011
- Author(s)
  Fujiwara N., Ihara K., Kato S., Yoshihara D., Eguchi H., Sakiyama H., Wakatsuki S., Taniguchi N. and Suzuki K
- Organizer
  12th Int. Congress on Amino Acids, Peptides and Proteins, Beijing 2011
- Place of Presentation
  Beijing, China
- Data Source
  KAKENHI-PROJECT-23591259
[Presentation] TWO TYPES OF LOOP VI STRUCTURE IN COPPER ZINC SUPEROXIDE DISMUTASE2011
- Author(s)
  Fujiwara N., Ihara K., Yamaguchi Y., Torigoe H., Yoshihara D., Eguchi H., Sakiyama H., Wakatsuki S., Taniguchi N. and Suzuki K
- Organizer
  5th Biennial Meeting of SFRR Asia (5th SFRR Asia)
- Place of Presentation
  Kagoshima, Japan
- Data Source
  KAKENHI-PROJECT-23591259
[Presentation] ヒトSOD1ダイマーのループVI構造は非対称である2011
- Author(s)
  藤原範子、伊原健太郎、鳥越秀峰、山口芳樹、若槻壮市、谷口直之、鈴木敬一郎
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23591259
[Presentation] 2-メルカプトエタノール修飾型Cu,Zn-SODの構造解析と安定性について2010
- Author(s)
  藤原範子
- Organizer
  第33回日本分子生物学会第83回日本生化学会大会合同大会(BMB2010)
- Place of Presentation
  神戸ポートアイランド(神戸)
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-20590320
[Presentation] SOD1ノックアウトマウスの腎臓における鉄代謝異常2009
- Author(s)
  吉原大作、藤原範子、崎山晴彦、江口裕伸、鈴木敬一郎
- Organizer
  第63回日本酸化ストレス学会学術集会
- Place of Presentation
  神奈川
- Year and Date
  2009-06-24
- Data Source
  KAKENHI-PROJECT-20590320
[Presentation] 抗酸化能を獲得した2-メルカプトエタノール修飾型Cu,Zn-SODの構造解析2009
- Author(s)
  藤原範子
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸ポートアイランド(神戸)
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-19500313
[Presentation] 抗酸化能を獲得した2-メルカプトエタノール修飾型Cu,Zn-SODの構造解析2009
- Author(s)
  藤原範子、伊原健太郎、若槻壮市、谷口直之、鈴木敬一郎
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20590320
[Presentation] 抗酸化能を獲得した2-メルカプトエタノール修飾型Cu, Zn-SODの構造解析2009
- Author(s)
  藤原範子、伊原健太郎、若槻壮市、谷口直之、鈴木敬一郎
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-19500313
[Presentation] 2ME化SOD1の結晶構造解析2009
- Author(s)
  伊原健太郎、藤原範子、富本裕介、若槻壮市、谷口直之、鈴木敬一郎
- Organizer
  第26回PFシンポジウム
- Place of Presentation
  つくば
- Data Source
  KAKENHI-PROJECT-19500313
[Presentation] Oxidative modification of Cys111 residue in human Copper/zinc superoxide dismutase and its immuno-probe2009
- Author(s)
  Fujiwara N., Nakano M., Kato S., Yoshihara D., Eguchi H., Sakiyama H., Taniguchi N., Suzuki K
- Organizer
  The 5th Joint Meeting of The Societies For Free Radical Research Australasia and Japan
- Place of Presentation
  Sydney, Australia
- Data Source
  KAKENHI-PROJECT-19500313
[Presentation] 抗酸化能を獲得した2-メルカプトエタノール修飾型Cu,Zn-SODの構造解析2009
- Author(s)
  藤原範子
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸ポートアイランド(神戸)
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-20590320
[Presentation] 2ME化SOD1の結晶構造解析2009
- Author(s)
  伊原健太郎、藤原範子、富本裕介、若槻壮市、谷口直之、鈴木敬一郎
- Organizer
  第26回PFシンポジウム
- Place of Presentation
  つくば
- Data Source
  KAKENHI-PROJECT-20590320
[Presentation] SOD1ノックアウトマウスの腎臓における鉄代謝異常とその分子機構2009
- Author(s)
  吉原大作、藤原範子、崎山晴彦、江口裕伸、鈴木敬一郎
- Organizer
  第83回日本生化学会大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20590320
[Presentation] Oxidative modification of Cys111 residue in human Copper/zinc superoxide dismutase and its immuno-probe2009
- Author(s)
  Fujiwara N., Nakano M., Kato S., Yoshihara D., Eguchi H., Sakiyama H., Taniguchi N., Suzuki K.
- Organizer
  The 5th Joint Meeting of The Societies For Free Radical Research Australasia and Japan
- Place of Presentation
  Sydney, Australia
- Data Source
  KAKENHI-PROJECT-20590320
[Presentation] Oxidative modification of Cys111 residue in human Copper/zinc superoxide dismutase and its immuno-probe2009
- Author(s)
  Fujiwara N.
- Organizer
  The 5th Joint Meeting of The Societies For Free Radical Research Australasia and Japan
- Place of Presentation
  Sydney University(Sydney, Australia)
- Year and Date
  2009-12-03
- Data Source
  KAKENHI-PROJECT-20590320
[Presentation] Oxidative modification of Cys 111 residue in human Copper/zinc superoxide dismutase and its immuno-probe2009
- Author(s)
  Fujiwara N.
- Organizer
  The 5th Joint Meeting of The Societies For Free Radical Research Australasia and Japan
- Place of Presentation
  Sydney University (Sydney, Australia)
- Year and Date
  2009-12-03
- Data Source
  KAKENHI-PROJECT-19500313
[Presentation] GSTA4-4 as a biomarker of oxidative stress in renal tubular cells2008
- Author(s)
  Yoshihara D., Fujiwara N., Ookawara T., Yokoe S., Suzuki K.
- Organizer
  BOSHD2008 Biomarkers of Oxidative Stress in Health and Diseases
- Place of Presentation
  Osaka
- Data Source
  KAKENHI-PROJECT-20590320
[Presentation] Cys111 in human copper-zinc-superoxide dismutase is a primary target for peroxidation to cysteine sulfonic acid2008
- Author(s)
  Fujiwara, N.
- Organizer
  The Gordon Research conference on Thiol-based Redox Regulation and Signaling
- Place of Presentation
  イタリア
- Data Source
  KAKENHI-PROJECT-19500313
[Presentation] Cys111 in human copper-zinc-superoxide dismutase is a primary target for peroxidation to cysteine sulfonic acid2008
- Author(s)
  Fujiwara N., Nakano M., Yoshihara D., Ookawara T., Eguchi H., Taniguchi N., Suzuki K.
- Organizer
  The Gordon Research conference on Thiol-based Redox Regulation and Signaling
- Place of Presentation
  Lucca, Italy
- Data Source
  KAKENHI-PROJECT-20590320
[Presentation] ヒトCu/Zn-スーパーオキシドジスムターゼ(SOD1)のCys111の酸化と酸化型SOD1特異抗体の作製2008
- Author(s)
  藤原範子、中の三弥子、大河原知水、吉原大作、横江俊一、加藤信介、谷口直之、鈴木敬一郎
- Organizer
  第61回日本酸化ストレス学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19500313
[Presentation] ヒトCu/Zn-スーパーオキシドジスムターゼ(SOD1)のCys111の酸化と酸化型SOD1特異抗体の作製2008
- Author(s)
  藤原範子, ほか
- Organizer
  第61回日本酸化ストレス学会学術集会
- Place of Presentation
  国立京都国際会館
- Data Source
  KAKENHI-PROJECT-19590605
[Presentation] SOD1ノックアウトマウスにおけるGSTA4の誘導と生理的意義2008
- Author(s)
  吉原大作、藤原範子、大河原知水、崎山晴彦、横江俊一、江口裕伸、鈴木敬一郎
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会(BMB2008)(p14)
- Place of Presentation
  神戸(Late-Breaking Abstracts)
- Data Source
  KAKENHI-PROJECT-20590320
[Presentation] Cys111 in human copper-zinc-superoxide dismutase is a primary target for peroxidation to cysteine sulfonic acid2008
- Author(s)
  Fujiwara N., Nakano M., Yoshihara D., Ookawara T., Eguchi H., Taniguchi N., Suzuki K
- Organizer
  The Gordon Research conference on Thiol-based Redox Regulation and Signaling
- Place of Presentation
  Lucca, Italy
- Data Source
  KAKENHI-PROJECT-19500313
[Presentation] ヒトCu/Zn-スーパーオキシドジスムターゼ(SOD1)のCys111の酸化と酸化型SOD1特異抗体の作製2008
- Author(s)
  藤原範子
- Organizer
  第61回日本酸化ストレス学会学術集会
- Place of Presentation
  京都市
- Data Source
  KAKENHI-PROJECT-19590605
[Presentation] Cu/Zn-SODノックアウトマウスにおけるGSTA4の生理的意義2008
- Author(s)
  吉原大作、藤原範子、大河原知水、横江俊一、崎山晴彦、鈴木敬一郎
- Organizer
  第61回日本酸化ストレス学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20590320
[Presentation] ヒトCu/Zn-スーパーオキシドジスムターゼ(SOD1)のCys111の酸化と酸化型SOD1特異抗体の作製2008
- Author(s)
  藤原範子、中の三弥子、大河原知水、吉原大作、横江俊一、加藤信介、谷口直之、鈴木敬一郎
- Organizer
  第61回日本酸化ストレス学会学術集会(p66)
- Place of Presentation
  京都(抄録)
- Data Source
  KAKENHI-PROJECT-20590320
[Presentation] Cys_<111> in human copper-zinc-superoxide dismutase is a primary target for peroxidation to cysteine sulfonic acid.2008
- Author(s)
  Fujiwara, N, ほか
- Organizer
  The Gordon Research conference on Thiolbased Redox Regulation and Signaling
- Place of Presentation
  Lucca, Italy
- Data Source
  KAKENHI-PROJECT-19590605
[Presentation] Cys111 in human copper-zinc-superoxide dismutase is a primary target for peroxidation to cysteine sulfonic acid.2008
- Author(s)
  Fujiwara, N
- Organizer
  The Gordon Research conference on Thiol-based Redox Regulation and Signaling
- Place of Presentation
  Lucca, Italy
- Data Source
  KAKENHI-PROJECT-19590605
[Presentation] Effects of copper metabolism on behavioral functions and brain monoamine contents in Wistar and Wilson's disease model rats2007
- Author(s)
  Fujiwara, N., Iso, H., Kitanaka, N., Kitanaka, J., Yoshihara, D., Ookawara, T., Suzuki, K
- Organizer
  ISTERH2007
- Place of Presentation
  Crete, Greece
- Data Source
  KAKENHI-PROJECT-19500313
[Presentation] Role of Cys111 in an oxidative damage of human Cu/Zn-superoxide dismutase2007
- Author(s)
  Fujiwara, N., Nakano, M., Yoshihara, D., Ookawara, T., Eguchi, H., Taniguchi, N., Suzuki, K
- Organizer
  第30回日本神経科学大会、第50回日本神経化学会大会、第17回日本神経回路学会大会、合同大会(Neuro 2007)
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19500313
[Presentation] Role of Cys111 in an oxidative damage of human Cu/Zn-superoxide dismutase2007
- Author(s)
  Fujiwara, N.
- Organizer
  第30回日本神経科学大会、第50回日本神経化学会大会、第17回日本神経回路学会大会、合同大会(Neuro2007)
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19500313
[Presentation] SOD1欠損が脳機能に与える影響　Behavioral and neurobiological changes in SOD1 deficient mice
- Author(s)
  吉原大作、藤原範子、崎山晴彦、江口裕伸、鈴木敬一郎
- Organizer
  第８６回日本生化学大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24500877
[Presentation] 酸化ストレス亢進が鉄代謝調節機構に与える影響
- Author(s)
  吉原大作、藤原範子、加藤信介、崎山晴彦、江口裕伸、鈴木敬一郎
- Organizer
  第66回日本酸化ストレス学会学術集会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-24500877
[Presentation] SOD1の酸化修飾および構造解析---ALS病態への関与---
- Author(s)
  藤原範子
- Organizer
  レドックス・ライフイノベーション第170委員会、第6回夏の委員会
- Place of Presentation
  弘前
- Invited
- Data Source
  KAKENHI-PROJECT-23591259
[Presentation] Alterations in renal iron metabolism caused by SOD1 deficiency
- Author(s)
  Daisaku Yoshihara, Noriko Fujiwara, Haruhiko Sakiyama, Hironobu Eguchi, and Keiichiro Suzuki
- Organizer
  SFRRI2014
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-24500877
[Presentation] SOD1KOマウスに発症する肝障害への糖・脂質代謝の関与の検討
- Author(s)
  米岡由佳、崎山晴彦、藤原範子、江口裕伸、吉原大作、鈴木敬一郎
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-25350911
[Presentation] 酸化ストレスによる肝線維化のメイラード反応生成物の関与
- Author(s)
  米岡由佳、崎山晴彦、藤原範子、江口裕伸、吉原大作、鈴木敬一郎
- Organizer
  第24回日本メイラード学会年会
- Place of Presentation
  熊本
- Year and Date
  2014-11-07 – 2014-11-08
- Data Source
  KAKENHI-PROJECT-25350911
[Presentation] 酸化ストレスが細胞内鉄イオン動態に与える影響
- Author(s)
  吉原大作、藤原範子、崎山晴彦、江口裕伸、鈴木敬一郎
- Organizer
  第67回　日本酸化ストレス学会学術集会
- Place of Presentation
  京都
- Year and Date
  2014-09-04 – 2014-09-05
- Data Source
  KAKENHI-PROJECT-24500877
[Presentation] 糖化と酸化ストレスによる脂質代謝異常
- Author(s)
  米岡由佳, 崎山晴彦, 藤原範子, 江口裕伸, 吉原大作, 鈴木敬一郎
- Organizer
  第23回日本メイラード学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-24500877
[Presentation] SOD1 KO マウスの肝臓における糖および脂質代謝の検討
- Author(s)
  米岡由佳, 崎山晴彦, 藤原範子, 江口裕伸, 吉原大作, 鈴木敬一郎
- Organizer
  第60回生化学会近畿支部例会
- Place of Presentation
  吹田
- Data Source
  KAKENHI-PROJECT-24500877
[Presentation] SOD1KOマウスに発症する肝障害への糖・脂質代謝の関与の検討
- Author(s)
  米岡由佳、崎山晴彦、藤原範子、江口裕伸、吉原大作、鈴木敬一郎
- Organizer
  第87回　日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-24500877
[Presentation] 酸化ストレスと転写因子Carbohydrate Response Element-Binding Protein (ChREBP)活性化について
- Author(s)
  崎山晴彦、米岡由佳、藤原範子、江口裕伸、吉原大作、鈴木敬一郎
- Organizer
  第87回　日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-24500877
[Presentation] 溶液酸素NMRによる酸化修飾タンパク質の新規検出方法
- Author(s)
  藤原範子、花島慎弥、山口芳樹、鄭国慶、鳥越秀峰、谷口直之、鈴木敬一郎
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23591259
[Presentation] SOD1KOマウスの肝疾患における糖・脂質代謝異常の寄与の検討
- Author(s)
  崎山晴彦、米岡由佳、藤原範子、江口裕伸、吉原大作、鈴木敬一郎
- Organizer
  第67回日本酸化ストレス学会
- Place of Presentation
  京都
- Year and Date
  2014-09-04 – 2014-09-05
- Data Source
  KAKENHI-PROJECT-25350911
[Presentation] 酸化ストレスと転写因子Carbohydrate Response Element-Binding Protein (ChREBP)活性化について
- Author(s)
  崎山晴彦、米岡由佳、藤原範子、江口裕伸、吉原大作、鈴木敬一郎
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-25350911
[Presentation] 酸化ストレスによる肝線維化のメイラード反応生成物の関与
- Author(s)
  米岡由佳、崎山晴彦、藤原範子、江口裕伸、吉原大作、鈴木敬一郎
- Organizer
  第24回日本メイラード学会年会
- Place of Presentation
  熊本
- Year and Date
  2014-11-07 – 2014-11-08
- Data Source
  KAKENHI-PROJECT-24500877
[Presentation] 酸素NMRによる酸化型SOD1の新規検出方法
- Author(s)
  藤原範子、花島慎弥、山口芳樹、鄭国慶、鳥越秀峰、谷口直之、鈴木敬一郎
- Organizer
  第66回日本酸化ストレス学会学術集会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23591259
[Presentation] SOD1欠損が脳内モノアミン代謝に与える影響
- Author(s)
  吉原大作、藤原範子、崎山晴彦、江口裕伸、鈴木敬一郎
- Organizer
  第87回　日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-24500877
[Presentation] Conserved acidic amino acid residues in the nuclear export signal of the RNA interacting domain regulates conformation and function of TDP-43
- Author(s)
  Makoto Urushitani, Akemi Shodai, Takashi Ayaki, Noriko Fujiwara, Hidefumi Ito
- Organizer
  Neuro 2013
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-23591259
[Presentation] SOD1 KOマウスの肝臓における糖および脂質代謝の検討
- Author(s)
  崎山晴彦, 江口裕伸, 吉原大作, 米岡由佳, 藤原範子, 鈴木敬一郎
- Organizer
  第８６回日本生化学大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24500877
[Presentation] Neurobiological and behavioral changes in SOD1 knockout mice
- Author(s)
  Daisaku Yoshihara, Noriko Fujiwara, Hiroyuki Iso, Nobue Kitanaka, Junichi Kitanaka, Hironobu Eguchi, Haruhiko Sakiyama, Motohiko Takemura and Keiichiro Suzuki
- Organizer
  Neuro2013
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-24500877
[Presentation] SOD1KOマウスの肝疾患における糖・脂質代謝異常の寄与の検討
- Author(s)
  崎山晴彦、米岡由佳、藤原範子、江口裕伸、吉原大作、鈴木敬一郎
- Organizer
  第67回　日本酸化ストレス学会
- Place of Presentation
  京都
- Year and Date
  2014-09-04 – 2014-09-05
- Data Source
  KAKENHI-PROJECT-24500877

1. SUZUKI Keiichiro (70221322)

# of Collaborated Projects: 20 results

# of Collaborated Products: 138 results
2. EGUCHI Hironobu (60351798)

# of Collaborated Projects: 18 results

# of Collaborated Products: 91 results
3. YOSHIHARA Daisaku (00567266)

# of Collaborated Projects: 16 results

# of Collaborated Products: 109 results
4. SAKIYAMA Haruhiko (30508958)

# of Collaborated Projects: 15 results

# of Collaborated Products: 86 results
5. OOKAWARA Tomomi (50330452)

# of Collaborated Projects: 8 results

# of Collaborated Products: 17 results
6. YOKOE Syunichi (40454756)

# of Collaborated Projects: 3 results

# of Collaborated Products: 7 results
7. KOREKANE Atsuko (80461169)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. URUSHITANI Makoto (60332326)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
9. KUROTSU Tositsugu (20098528)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 井原秀之 (50452834)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
11. 鎌田洋一 (20152837)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 長井薫 (20340953)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 八木千鶴 (20425086)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 福島和明 (00273730)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. WAGATSUMA michiru

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
16. FURUKAWA yoshiaki

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
17. TOKUDA eiichi

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
18. TACHIBANA taro

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. KATO shinsuke

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 高橋良輔

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Fujiwara Noriko 藤原 範子

FUJIWARA Noriko 藤原 範子

Research Projects

Research Products

Co-Researchers

Elucidation of the molecular mechanism of ALS causative protein aggregate formation and pathogenesisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of intracellular aggregation mechanism of ALS-causing protein and development of aggregation inhibitorPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of ALS pathophysiology using monoclonal antibodies that specifically recognizes SOD1 aggregatesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Fujiwara Noriko 藤原範子

FUJIWARA Noriko 藤原範子

[Book] 改訂2版　集中講義　生化学2017