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Izumi Yasushi  泉 裕士

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Yasushi Izumi  泉 裕士

IZUMI Yasushi  泉 裕士

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Researcher Number 10373268
Other IDs
External Links
Affiliation (Current) 2025: 生理学研究所, 生体機能調節研究領域, 准教授
Affiliation (based on the past Project Information) *help 2025: 生理学研究所, 生体機能調節研究領域, 准教授
2019 – 2023: 生理学研究所, 生体機能調節研究領域, 准教授
2015 – 2017: 生理学研究所, 生体機能調節研究領域, 准教授
2015 – 2016: 生理学研究所, 大脳皮質機能研究系, 准教授
2014: 神戸大学, 医学(系)研究科(研究院), 准教授 … More
2009 – 2010: Kobe University, 医学研究科, 助教
2007: Kobe University, 大学院・医学系研究科, 助教
2005 – 2006: RIKEN, Cell Asymmetry, Special Postdoctral Fellow, 非対称細胞分裂研究グループ, 基礎科学特別研究員
2004: 独立行政法人理化学研究所, 非対称細胞分裂研究グループ, 研究員 Less
Review Section/Research Field
Principal Investigator
Basic Section 44010:Cell biology-related / Cell biology / Biological Sciences / Developmental biology
Except Principal Investigator
Developmental biology / Cell biology
Keywords
Principal Investigator
ショウジョウバエ / セプテートジャンクション / 上皮細胞 / 腸管 / 細胞増殖 / 幹細胞 / 組織恒常性 / 上皮バリア / 細胞間隙バリア / 細胞間接着装置 … More / 分裂方向 / 紡錘体 / 三量体G蛋白質 / 神経幹細胞 / 非対称分裂 / 腎管/マルピーギ管 / 細胞間結合 / 腸管恒常性 / 細胞間接着 / 閉塞結合 / 細胞接着 / バリア機能 / 上皮 / 発生・分化 / 細胞・組織 / 昆虫 / 遺伝子 / 遺伝学 / 細胞極性 / 細胞運命決定因子 / Gαi / Pins … More
Except Principal Investigator
aPKC / 上皮細胞 / epithelial cell / G-protein / cell polarity / asymmetric division / neural stem cell / Miranda / prospero / 非対称性 / 多様性 / miranda / PKC / G蛋白質 / 細胞極性 / 非対称分裂 / 神経幹細胞 / 上皮 / トリセルラージャンクション / MDCK細胞 / トリセルリン / アンギュリン / 遺伝性難聴 / 上皮バリア機能 / タイトジャンクション / 細胞接着 Less
  • Research Projects

    (9 results)
  • Research Products

    (41 results)
  • Co-Researchers

    (4 People)
  •  細胞間結合とaPKCによる腸管上皮幹細胞の増殖制御機構の解明Principal Investigator

    • Principal Investigator
      泉 裕士
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 44010:Cell biology-related
    • Research Institution
      National Institute for Physiological Sciences
  •  ショウジョウバエ上皮細胞間隙バリア機能低下による幹細胞増殖の促進機構の解明Principal Investigator

    • Principal Investigator
      泉 裕士
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 44010:Cell biology-related
    • Research Institution
      National Institute for Physiological Sciences
  •  The role of epithelial barrier in Drosophila intestinal homeostasisPrincipal Investigator

    • Principal Investigator
      Yasushi Izumi
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 44010:Cell biology-related
    • Research Institution
      National Institute for Physiological Sciences
  •  Analysis of mechanism involved in cell-cell junction formation using Drosophila as a model systemPrincipal Investigator

    • Principal Investigator
      Izumi Yasushi
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cell biology
    • Research Institution
      National Institute for Physiological Sciences
  •  The molecular mechanism underlying the epithelial barrier formation by tricellular tight junctions

    • Principal Investigator
      Furuse Mikio
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Cell biology
    • Research Institution
      National Institute for Physiological Sciences
      Kobe University
  •  Identification and characterization of novel proteins regulating epithelial barrier functionsPrincipal Investigator

    • Principal Investigator
      IZUMI Yasushi
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Cell biology
    • Research Institution
      Kobe University
  •  ショウジョウバエ神経幹細胞の非対称分裂における、三量体G蛋白質経路の役割Principal Investigator

    • Principal Investigator
      泉 裕士
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kobe University
      The Institute of Physical and Chemical Research
  •  ショウジョウバエ神経幹細胞の非対称分裂における三量体G蛋白質経路の役割Principal Investigator

    • Principal Investigator
      泉 裕士
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Developmental biology
    • Research Institution
      The Institute of Physical and Chemical Research
  •  Asymmetric cell division : mechanisms creating cell diversity from cell asymmetry

    • Principal Investigator
      MATSUZAKI Fumio
    • Project Period (FY)
      2001 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Developmental biology
    • Research Institution
      RIKEN
      Tohoku University

All 2023 2022 2021 2020 2019 2017 2016 2015 2014 2011 2010 2009 2006 2005 2004

All Journal Article Presentation

  • [Journal Article] Identification of the genes encoding candidate septate junction components expressed during early development of the sea urchin, Strongylocentrotus purpuratus, and evidence of a role for Mesh in the formation of the gut barrier2023

    • Author(s)
      Jonusaite Sima、Oulhen Nathalie、Izumi Yasushi、Furuse Mikio、Yamamoto Takashi、Sakamoto Naoaki、Wessel Gary、Heyland Andreas
    • Journal Title

      Developmental Biology

      Volume: 495 Pages: 21-34

    • DOI

      10.1016/j.ydbio.2022.12.007

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K06229, KAKENHI-PROJECT-21H02523
  • [Journal Article] Shortened lifespan induced by a high-glucose diet is associated with intestinal immune dysfunction in Drosophila sechellia2022

    • Author(s)
      Abe Maiko、Kamiyama Takumi、Izumi Yasushi、Qian Qingyin、Yoshihashi Yuma、Degawa Yousuke、Watanabe Kaori、Hattori Yukako、Uemura Tadashi、Niwa Ryusuke
    • Journal Title

      Journal of Experimental Biology

      Volume: 225 Issue: 21

    • DOI

      10.1242/jeb.244423

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K06229, KAKENHI-PUBLICLY-21H00251
  • [Journal Article] The novel membrane protein Hoka regulates septate junction organization and stem cell homeostasis in the Drosophila gut2021

    • Author(s)
      Izumi Yasushi、Furuse Kyoko、Furuse Mikio
    • Journal Title

      Journal of Cell Science

      Volume: 134 Issue: 6 Pages: 257022-257022

    • DOI

      10.1242/jcs.257022

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18H02440, KAKENHI-PROJECT-19K06650
  • [Journal Article] The septate junction protein Mesh is required for epithelial morphogenesis, ion transport, and paracellular permeability in the Drosophila Malpighian tubule.2020

    • Author(s)
      Sima Jonusaite, Klaus W. Beyenbach, Heiko Meyer, Achim Paululat, Yasushi Izumi, Mikio Furuse, and Aylin R. Rodan
    • Journal Title

      American Journal of Physiology-Cell Physiology

      Volume: 318 Issue: 3 Pages: C675-C694

    • DOI

      10.1152/ajpcell.00492.2019

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K06650, KAKENHI-PROJECT-18H02440
  • [Journal Article] The extracellular domain of angulin-1 and palmitoylation of its cytoplasmic region are required for angulin-1 assembly at tricellular contacts2020

    • Author(s)
      Yukako Oda, Taichi Sugawara, Yuko Fukata, Yasushi Izumi, Tetsuhisa Otani, Tomohito Higashi, Masaki Fukata and Mikio Furuse
    • Journal Title

      Journal of Biological Chemistry

      Volume: 295 Pages: 4289-4302

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K06650
  • [Journal Article] The septate junction protein Tetraspanin 2A is critical to the structure and function of Malpighian tubules in Drosophila melanogaster.2020

    • Author(s)
      Klaus W Beyenbach, Frederike Schone, Leonhard F Breitsprecher, Felix Tiburcy, Mikio Furuse, Yasushi Izumi, Heiko Meyer, Sima Jonusaite, Aylin R Rodan, Achim Paululat
    • Journal Title

      American journal of physiology. Cell physiology

      Volume: 318 Issue: 6 Pages: C1107-C1122

    • DOI

      10.1152/ajpcell.00061.2020

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K06650, KAKENHI-PROJECT-18H02440
  • [Journal Article] Septate junctions regulate gut homeostasis through regulation of stem cell proliferation and enterocyte behavior in Drosophila.2019

    • Author(s)
      Yasushi Izumi, Kyoko Furuse and Mikio Furuse
    • Journal Title

      Journal of Cell Science

      Volume: 132 Issue: 18

    • DOI

      10.1242/jcs.232108

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K06650, KAKENHI-PROJECT-18H02440
  • [Journal Article] Molecular dissection of smooth septate junctions: understanding their roles in arthropod physiology.2017

    • Author(s)
      Mikio Furuse and Yasushi Izumi
    • Journal Title

      Annals of the New York Academy of Sciences

      Volume: 1397 Issue: 1 Pages: 17-24

    • DOI

      10.1111/nyas.13366

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K07048
  • [Journal Article] A tetraspanin regulates septate junction formation in Drosophila midgut2016

    • Author(s)
      Yasushi Izumi, Minako Motoishi, Kyoko Furuse and Mikio Furuse
    • Journal Title

      Journal of Cell Science

      Volume: 129 Issue: 6 Pages: 1155-1164

    • DOI

      10.1242/jcs.180448

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K07048, KAKENHI-PROJECT-26291043
  • [Journal Article] Molecular organization and function of invertebrate occluding junctions2014

    • Author(s)
      Izumi Y, Furuse M.
    • Journal Title

      Semin Cell Dev Biol

      Volume: 36 Pages: 186-193

    • DOI

      10.1016/j.semcdb.2014.09.009

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26291043
  • [Journal Article] Molecular organization of tricellular tight junctions2014

    • Author(s)
      Furuse M, Izumi Y, Oda Y, Higashi T, Iwamoto N
    • Journal Title

      Tissue Barriers

      Volume: 2 Issue: 3 Pages: e28960-e28960

    • DOI

      10.4161/tisb.28960

    • NAID

      130004756433

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26291043
  • [Journal Article] Phosphorylation state regulates the localization of Scribble at adherens junctions and its association with E-cadherin-catenin complexes.2011

    • Author(s)
      Yoshihara K, Ikenouchi J, Izumi Y, Akashi M, Tsukita S, Furuse M.
    • Journal Title

      Exp Cell Res. 317(4)

      Pages: 413-22

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21770210
  • [Journal Article] Drosophila Pins-binding protein Mud regulates spindle-polarity coupling and centrosome organization2006

    • Author(s)
      Yasushi Izumi, Nao Ohta, Kanako Hisata, Thomas Raabe, Fumio Matsuzaki
    • Journal Title

      Nature Cell Biology 8

      Pages: 586-593

    • Data Source
      KAKENHI-PROJECT-18057027
  • [Journal Article] Drosophila Pins-binding protein Mud regulates spindle-polarity coupling and centrosome organization.2006

    • Author(s)
      Izumi, Y., Ohta, N., Hisata K., Raabe, T., Matsuzaki, F.
    • Journal Title

      Nat.Cell Biol. (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13854027
  • [Journal Article] Drosophila Pins-binding protein Mud regulates spindle-polarity coupling and centrosome organization2006

    • Author(s)
      Izumi, Y.
    • Journal Title

      Nat.Cell Biol. (in press)

      Pages: 11-11

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13854027
  • [Journal Article] 非対称分裂を制御する細胞極性2005

    • Author(s)
      泉 裕士, 松崎 文雄
    • Journal Title

      細胞工学 24

      Pages: 247-251

    • Data Source
      KAKENHI-PROJECT-16770172
  • [Journal Article] ショウジョウバエ神経幹細胞の非対称分裂における三量体G蛋白質の役割2005

    • Author(s)
      泉 裕士, 松崎 文雄
    • Journal Title

      生化学 77

      Pages: 140-144

    • Data Source
      KAKENHI-PROJECT-16770172
  • [Journal Article] Differential functions of G protein and Baz/aPKC signaling pathways in Drosophila neuroblast asymmetric division.2004

    • Author(s)
      Izumi, Y.
    • Journal Title

      Journal of Cell Biology 164(5)

      Pages: 729-738

    • Data Source
      KAKENHI-PROJECT-13854027
  • [Journal Article] Differential functions of G protein and Baz/aPKC signaling pathways in Drosophila neuroblast asymmetric division.2004

    • Author(s)
      Izumi, Y., Ohta, N., Itoh-Furuya, A., Fuse, N., Matsuzaki, F.
    • Journal Title

      J.Cell Biol. 164

      Pages: 729-738

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13854027
  • [Journal Article] Differential functions of G protein and Baz-aPKC signaling pathways in Drosophila neuroblast asymmetric division2004

    • Author(s)
      Yasushi Izumi, Nao Ohta, Itoh-Furuya, Naoyuki Fuse, Fumio Matsuzaki
    • Journal Title

      The Journal of Cell Biology 164

      Pages: 729-738

    • Data Source
      KAKENHI-PROJECT-16770172
  • [Journal Article] Differential functions of G protein and Baz/aPKC signaling pathways in Drosophila neuroblast asymmetric division.2004

    • Author(s)
      Izumi, Y
    • Journal Title

      J.Cell Biol. 164

      Pages: 10-10

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13854027
  • [Presentation] ショウジョウバエ腸管の幹細胞増殖制御における細胞間隙バリアの役割.2023

    • Author(s)
      泉 裕士
    • Organizer
      2023年度生理研研究会「上皮膜輸送と細胞極性形成機構の統合的理解を目指して」
    • Data Source
      KAKENHI-PROJECT-22K06229
  • [Presentation] The role of paracellular diffusion barrier in the Drosophila intestinal and renal stem cell proliferation.2023

    • Author(s)
      泉 裕士、古瀬幹夫
    • Organizer
      第75回日本細胞生物学会大会
    • Data Source
      KAKENHI-PROJECT-22K06229
  • [Presentation] aPKCはショウジョウバエの腸管バリア機能の破綻に伴う腸管上皮幹細胞の増殖に関与する.2022

    • Author(s)
      泉 裕士、古瀬幹夫
    • Organizer
      第74回日本細胞生物学会大会
    • Data Source
      KAKENHI-PROJECT-22K06229
  • [Presentation] Septate junctions regulate renal stem cell proliferation in the Drosophila Malpighian tubules.2022

    • Author(s)
      Izumi Yasushi, Furuse Mikio.
    • Organizer
      第15回日本ショウジョウバエ研究会
    • Data Source
      KAKENHI-PROJECT-22K06229
  • [Presentation] The novel membrane protein Hoka regulates septate junction organization and stem cell homeostasis in the Drosophila intestine.2021

    • Author(s)
      Yasushi Izumi、Mikio Furuse
    • Organizer
      The 14th Japanese Drosophila Research Conference
    • Data Source
      KAKENHI-PROJECT-19K06650
  • [Presentation] 新規膜タンパク質Hokaによるショウジョウバエ腸管のセプテートジャンクション形成と幹細胞恒常性の制御2021

    • Author(s)
      泉 裕士、古瀬幹夫
    • Organizer
      第73回日本細胞生物学会
    • Data Source
      KAKENHI-PROJECT-19K06650
  • [Presentation] 新規膜タンパク質Hokaによるショウジョウバエ腸管のセプテートジャンクション形成と幹細胞恒常性の制御2020

    • Author(s)
      泉 裕士、古瀬幹夫
    • Organizer
      第43回日本分子生物学会
    • Data Source
      KAKENHI-PROJECT-19K06650
  • [Presentation] ショウジョウバエ腸管の恒常性における上皮バリア機能の役割.2020

    • Author(s)
      泉 裕士、古瀬幹夫
    • Organizer
      第9回生理研・名古屋大学医学部合同シンポジウム
    • Data Source
      KAKENHI-PROJECT-19K06650
  • [Presentation] 多様な膜貫通タンパク質により構成されるショウジョウバエのセプテートジャンクション2019

    • Author(s)
      泉 裕士、古瀬幹夫
    • Organizer
      第19回日本蛋白質化学会年会、第71回 日本細胞生物学会 合同年次大会
    • Data Source
      KAKENHI-PROJECT-19K06650
  • [Presentation] Identification and characterization of novel membrane proteins required for septate junction formation in Drosophila midgut.2017

    • Author(s)
      Yasushi Izumi and Mikio Furuse
    • Organizer
      4th Asia-Pacific Drosophila Research Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K07048
  • [Presentation] Identification and characterization of novel membrane proteins required for septate junction formation in Drosophila midgut2017

    • Author(s)
      泉裕士、古瀬幹夫
    • Organizer
      4th Asia-Pacific Drosophila Research Conference, APDRC4
    • Place of Presentation
      大阪大学吹田キャンパスコンベンションセンター(大阪府吹田市)
    • Year and Date
      2017-05-08
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K07048
  • [Presentation] 腸管の恒常性における上皮バリア機能の役割2017

    • Author(s)
      泉 裕士、古瀬幹夫
    • Organizer
      2017年度生命科学系学会合同年次大会
    • Data Source
      KAKENHI-PROJECT-15K07048
  • [Presentation] ショウジョウバエ内胚葉上皮のセプテートジャンクションの形成機構2016

    • Author(s)
      泉裕士
    • Organizer
      第68回日本細胞生物学会大会
    • Place of Presentation
      京都テルサ(京都府京都市)
    • Year and Date
      2016-06-15
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K07048
  • [Presentation] Identifications and characterizations of novel smooth septate junction proteins in Drosophila2016

    • Author(s)
      泉裕士
    • Organizer
      International conference Tight junction and their proteins
    • Place of Presentation
      Harnack House(ドイツ ベルリン)
    • Year and Date
      2016-09-08
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K07048
  • [Presentation] ショウジョウバエ内胚葉上皮のセプテートジャンクションの形成機構2016

    • Author(s)
      泉裕士
    • Organizer
      第68回日本細胞生物学会大会
    • Place of Presentation
      京都府京都市 京都テルサ
    • Year and Date
      2016-06-15
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K07048
  • [Presentation] ショウジョウバエ腸管上皮細胞のセプテートジャンクション形成に関与する分子群の同定2015

    • Author(s)
      泉裕士、元石美奈子、今川裕貴、古瀬幹夫
    • Organizer
      第38回日本分子生物学会、第88回日本生化学会大会 合同大会
    • Place of Presentation
      兵庫県神戸市 神戸ポートアイランド
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-15K07048
  • [Presentation] Molecular dissection of septate junctions in the insect midgut and malpighian tubules2015

    • Author(s)
      Furuse M, Izumi Y
    • Organizer
      Society for Experimental Biology Annual Main Meeting
    • Place of Presentation
      Prague, Czech Republic
    • Year and Date
      2015-06-30
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26291043
  • [Presentation] ショウジョウバエのスムースセプテートジャンクションに局在する新規細胞接着タンパク質の同定と機能解析2010

    • Author(s)
      泉裕士、柳橋祐一、古瀬幹夫
    • Organizer
      第33回日本分子生物学会年会
    • Place of Presentation
      ポートピアホテル(神戸市)
    • Year and Date
      2010-12-07
    • Data Source
      KAKENHI-PROJECT-21770210
  • [Presentation] ショウジョウバエのスムースセプテートジャンクションに局在する新規細胞接着タンパク質の同定と機能解析2010

    • Author(s)
      泉裕士
    • Organizer
      第33回日本分子生物学会年会
    • Place of Presentation
      ポートピアホテル(兵庫県)
    • Year and Date
      2010-12-07
    • Data Source
      KAKENHI-PROJECT-21770210
  • [Presentation] Identification and characterization of a novel smooth septate junction component2009

    • Author(s)
      泉裕士、柳橋祐一、古瀬幹夫
    • Organizer
      The 9^<th> Japanese Drosophila Research Conference
    • Place of Presentation
      ヤマハリゾートつま恋(静岡県)
    • Year and Date
      2009-07-06
    • Data Source
      KAKENHI-PROJECT-21770210
  • 1.  Furuse Mikio (90281089)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 2.  MATSUZAKI Fumio (10173824)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 3.  菅原 太一 (30758412)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  布施 直之 (80321983)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results

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