SHIMIZU YASUSHI 清水康

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SHIMIZU Yasushi 清水康

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Researcher Number	10374513
Other IDs
Affiliation (Current)	2025: 北海道大学, 大学病院, 講師
Affiliation (based on the past Project Information) *help	2012 – 2013: 北海道大学, 大学病院, 助教 2011: 北海道大学, 医学(系)研究科(研究院), 助教
Review Section/Research Field	Except Principal Investigator Respiratory organ internal medicine
Keywords	Except Principal Investigator 分子標的薬 / エピジェネティクス / HDAC / cJun / 幹細胞 / EZH2 / ｃJun / 癌幹細胞 / 肺癌

Targeted therapy for cancer stem-like cells of non-small cell lung cancers with inhibition of the cJun transcription factor
- Principal Investigator
  
  KINOSHITA Ichiro
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Hokkaido University

All 2012 2011 Other

All Journal Article Presentation

[Journal Article] Epigenetic therapy with 3-deazaneplanocin A, an inhibitor of the histone methyltransferase EZH2, inhibits growth of non-small cell lung cancer cells2012
- Author(s)
  Kikuchi J, Takashina T, Kinoshita I, Kikuchi E, Shimizu Y, Sakakibara-Konishi J, Oizumi S, Marquez VE, Nishimura M, Dosaka-Akita H
- Journal Title
  
  Lung Cancer
  
  Volume: 78 Issue: 2 Pages: 138-143
- DOI
  10.1016/j.lungcan.2012.08.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591132
[Journal Article] Minichromosome maintenance (MCM) protein 4 as a marker for proliferation and its clinical and clinicopathological significance in non-small cell lung cancer2011
- Author(s)
  Kikuchi J, Kinoshita I, Shimizu Y, Kikuchi E, Takeda K, Aburatani H, Oizumi S, Konishi J, Kaga K, Matsuno Y, Birrer MJ, Nishimura M and Dosaka-Akita H
- Journal Title
  
  Lung Cancer
  
  Volume: 72 Issue: 2 Pages: 229-237
- DOI
  10.1016/j.lungcan.2010.08.020
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591132
[Journal Article] Expression of LGR5, an intestinal stem cell marker, during each stage of colorectal tumorigenesis2011
- Author(s)
  Takeda K, Kinoshita I, Shimizu Y, Matsuno Y, Shichinohe T and Dosaka-Akita H
- Journal Title
  
  Anticancer Res
  
  Volume: 31 Pages: 263-270
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591132
[Presentation] Growth inhibition of non-small cell lung cancer cells by the histone methyltransferase ezh2 inhibitor 3-deazaneplanocin2011
- Author(s)
  Kinoshita I, Kikuchi J, Shimizu Y, Sakakibara-Konishi J, Oizumi S, Nishimura M, Dosaka-Akita H
- Organizer
  9th International Symposium for Future Drug Discovery and Medical Care
- Place of Presentation
  北海道大学（札幌市）
- Data Source
  KAKENHI-PROJECT-23591132
[Presentation] Growth inhibition of non-small cell lung cancer cells by the histone methyltransferase EZH2 inhibitor 3-deazaneplanocin2011
- Author(s)
  木下一郎，菊地順子，菊地英毅, 清水康, 榊原純, 大泉聡史, 西村正治, 秋田弘俊
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知）
- Data Source
  KAKENHI-PROJECT-23591132
[Presentation] ヒストンメチル化酵素EZH2阻害剤3-deazaneplanocin Aによる非小細胞肺癌細胞株に対する増殖抑制効果の検討
- Author(s)
  高階太一、木下一郎、菊地順子、菊地英毅、清水康、榊原純、大泉聡史、西村正治、秋田弘俊
- Organizer
  第53回日本肺癌学会総会
- Place of Presentation
  岡山コンベンションセンター（岡山市）
- Data Source
  KAKENHI-PROJECT-23591132
[Presentation] Effects of combined epigenetic therapy with EZH2 and HDAC inhibitors on NSCLC cells
- Author(s)
  Takashina T, Kinoshita I, Kikuchi J, Kikuchi E, Shimizu Y, Sakakibara-Konishi J, Oizumi S, Nishimura M and Dosaka-Akita H
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Data Source
  KAKENHI-PROJECT-23591132
[Presentation] Effects of combined epigenetic therapy with the histone methyltransferase EZH2 inhibitor 3-deazaneplanocin and the histone deacetylase inhibitor SAHA on non-small cell lung cancer cells
- Author(s)
  Takashina T, Kinoshita I, Kikuchi J, Shimizu Y, Konishi JS, Oizumi S, Nishimura M and Dosaka-Akita H
- Organizer
  the 105th Annual Meeting of the American Association for Cancer Research
- Place of Presentation
  San Diego Conventon Center (San Diego)
- Data Source
  KAKENHI-PROJECT-23591132

1. KINOSHITA Ichiro (40343008)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results

SHIMIZU YASUSHI 清水 康

SHIMIZU Yasushi 清水 康

Research Projects

Research Products

Co-Researchers

Targeted therapy for cancer stem-like cells of non-small cell lung cancers with inhibition of the cJun transcription factor

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Epigenetic therapy with 3-deazaneplanocin A, an inhibitor of the histone methyltransferase EZH2, inhibits growth of non-small cell lung cancer cells2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Minichromosome maintenance (MCM) protein 4 as a marker for proliferation and its clinical and clinicopathological significance in non-small cell lung cancer2011

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Expression of LGR5, an intestinal stem cell marker, during each stage of colorectal tumorigenesis2011

Author(s)

Journal Title

Data Source

[Presentation] Growth inhibition of non-small cell lung cancer cells by the histone methyltransferase ezh2 inhibitor 3-deazaneplanocin2011

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Growth inhibition of non-small cell lung cancer cells by the histone methyltransferase EZH2 inhibitor 3-deazaneplanocin2011

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] ヒストンメチル化酵素EZH2阻害剤3-deazaneplanocin Aによる非小細胞肺癌細胞株に対する増殖抑制効果の検討

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Effects of combined epigenetic therapy with EZH2 and HDAC inhibitors on NSCLC cells

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Effects of combined epigenetic therapy with the histone methyltransferase EZH2 inhibitor 3-deazaneplanocin and the histone deacetylase inhibitor SAHA on non-small cell lung cancer cells

Author(s)

Organizer

Place of Presentation

Data Source

SHIMIZU YASUSHI 清水康

SHIMIZU Yasushi 清水康