Kitamura Takanori 北村剛規

… Alternative Names

KITAMURA Takanori 北村剛規

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Researcher Number	10378622
Affiliation (Current)	2025: 京都大学, 医学研究科, 助教
Affiliation (based on the past Project Information) *help	2012: 京都大学, 大学院・医学研究科, 助教 2006 – 2009: 京都大学, 医学研究科, 助教 2004 – 2006: Kyoto University, Graduate School of Medicine, Assistant Professor, 医学研究科, 助手
Review Section/Research Field	Principal Investigator Experimental pathology Except Principal Investigator Pathological medical chemistry / Biological Sciences
Keywords	Principal Investigator 大腸癌 / 抗癌剤 / c-KIT / 腫瘍・マウスモデル・大腸癌 Except Principal Investigator COX-2 / マイクロアレイ / 病理学 / 癌 / トランスジェニックマウス / 転移 … More / APC / Notch / 分子腫瘍学 / 間質細胞 / Apc / Lkb1 / 血管新生 / LKB1 / CXCR3 / ケモカイン / LKB 1 / Pathology / Cancer / Transgenic mouse / Stromal cells / Prostaglandin / EP2 / PGE_2 / cPLA2 / ポリープ / β-catenin / Smad2 / ノックアウトマウス / 肝癌 / 大腸癌 / TGF-βシグナル / 線維芽細胞 / Fhit / プロスタグランジン / 消化器癌 / 未分化骨髄球 / マウスモデル / 消化器がん / 細胞・組織 / MMP7 / mTORC1 / 遺伝子改変マウス / シグナル伝達 / 炎症 / mPGES / LYVE-1 / リンパ管新生 / B16F10 / mTOR / Cdx2 / プロテオミクス / マクロファージ / 染色体不安定性 / Wnt / CDX2 / CCL9 / CCR1 / 同所移植 / 浸潤 Less

StudiesonMetastasisofDigestiveCancersUsingMouseModels
- Principal Investigator
  
  TAKETO Makoto
- Project Period (FY)
  2009 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kyoto University
The role of c-KIT positive cancer cells in a drug resistance of the intestinal tumorsPrincipal Investigator
- Principal Investigator
  
  KITAMURA Takanori
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Experimental pathology
- Research Institution
  Kyoto University
Studies on digestive cancer metastasis using mouse models
- Principal Investigator
  
  TAKETO Makoto
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kyoto University
Epitehial-stromal interactions and molecularly targeted therapy
- Principal Investigator
  
  TAKETO Makoto
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
消化器癌の転移機構とその治療の研究
- Principal Investigator
  
  TAKETO Makoto
- Project Period (FY)
  2002 – 2006
- Research Category
  
  Grant-in-Aid for Creative Scientific Research
- Research Institution
  Kyoto University
Epithelium-stroma interactions in carcinogenesis
- Principal Investigator
  
  TAKETO Makoto Mark
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  KYOTO UNIVERSITY

All 2011 2010 2009 2007 Other

All Journal Article Presentation

[Journal Article] Molecular mechanisms of liver metastasis2011
- Author(s)
  Kawada K, HaSegawa S, Murakami T, Itatani Y, Hosogi H, Sonoshita M, Kitamura T, Fujishita T, Iwamoto M, Matsumoto T, Matsusue R, Hida K, Akiyaraa G, Okoshi K, Yamada M, Kawamura J, Taketo MM, Sakai Y
- Journal Title
  
  Int J Clin Oncol
  
  Volume: 16 Issue: 5 Pages: 464-472
- DOI
  10.1007/s10147-011-0307-2
- NAID
  10030246531
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229005, KAKENHI-PROJECT-22791276, KAKENHI-PROJECT-23680088
[Journal Article] Suppression of colon cancer metastasis by Aes through inhibition of Notch signaling2011
- Author(s)
  Sonoshita M, Aoki M, Fuwa H, Aoki K, Hosogi H, Sakai Y, Hashida H, Takabayashi A, Sasaki M, Robine S, Itoh K, Yoshioka K, Kakizaki F, Kitamura K, Oshima M, and Taketo MM.
- Journal Title
  
  Cancer Cell
  
  Volume: 19 Pages: 125-137
- Data Source
  KAKENHI-PROJECT-21229005
[Journal Article] Suppression of colon cancer metastasis by Aes through inhibition of Notch signaling.2011
- Author(s)
  Sonoshita M, Aoki M, Fuwa H, Aoki K, Hosogi H, Sakai Y, Hashida H, Takabayashi A, Sasaki M, Robine S, Itoh K, Yoshioka K, Kakizaki F, Kitamura K, Oshima M, Taketo MM.
- Journal Title
  
  Cancer Cell
  
  Volume: 19 Pages: 125-137
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229005
[Journal Article] Inactivation of CCR1 suppresses colon cancer liver metastasis by blocking accumulation of immature myeloid cells in a mouse model.2010
- Author(s)
  Kitamura T, Fujishita T, Loetscher P, Revesz L, Hashida H, Kizaka-Kondoh S, Aoki M, Taketo MM.
- Journal Title
  
  Proc.Natl.Acad.Sci.USA
  
  Volume: 107 Pages: 13063-13068
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229005
[Journal Article] Inactivation of CCR1 suppresses colon cancer liver metastasis by blocking accumulation of immature myeloid cells in a mouse model2010
- Author(s)
  Kitamura T, Fujishita T, Loetscher P, Revesz L, Hashida H, Kizaka-Kondoh S, Aoki M, and Taketo MM.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA
  
  Volume: 107 Pages: 13063-13068
- Data Source
  KAKENHI-PROJECT-21229005
[Journal Article] Matrix metalloproteinase 7 is required for tumor formation, but dispensable for invasion and fibrosis in SMAD4-deficient intestinal adenocarcinomas.2009
- Author(s)
  Kitamura, T., et al.
- Journal Title
  
  Lab Invest. 89
  
  Pages: 98-105
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209010
[Journal Article] Reduced level of smoothened suppresses intestinal tumorigenesis by down-regulation of Wne signaling.2009
- Author(s)
  Arimura S, Matsunaga A, Kitamura T, Aoki K, Aoki M, Taketo MM.
- Journal Title
  
  Gastroenterology 137(2)
  
  Pages: 629-638
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790303
[Journal Article] Matrix metalloproteinase 7 is required for tumor formation, but dispensable for invasion and fibrosis in SMAD4 -deficient intestinal adenocarcinomas2009
- Author(s)
  Kitamura, T., Biyajima, K., Aoki, M., Oshima, M., Taketo, M. M.
- Journal Title
  
  Lab Invest 89
  
  Pages: 98-105
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209010
[Journal Article] Matrix metalloproteinase 7 is required for tumor formation, but dispensable for invasion and fibrosis in SMAD4-deficient intestinal adenocarcinomas2009
- Author(s)
  Kitamura T, et.al.
- Journal Title
  
  Laboratory Investigation 89
  
  Pages: 98-105
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790303
[Journal Article] Matrix metalloproteinase 7 is required for tumor formation, but indispensable for invasion and fibrosis in SMAD4-deficient intestinal adenocarcinomas.2009
- Author(s)
  Kitamura, T., Biyajima, K., Aoki, M., Oshima, M., Taketo, M.M.
- Journal Title
  
  Lab. Invest. 89
  
  Pages: 98-105
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016032
[Journal Article] Matrix metalloproteinase 7 is required for tumor formation, but dispensable for invasion and fibrosis in SMAD4-deficient intestinal adenocarcinomas2009
- Author(s)
  Kitamura, T., et.al.
- Journal Title
  
  Lab Invest 89
  
  Pages: 98-105
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016032
[Journal Article] Matrix metalloproteinase 7 is required for tumor formation, but dispensable for invasion and fibrosis in SMAD4-deficient intestinal adenocarcinomas2009
- Author(s)
  Kitamura T, et al.
- Journal Title
  
  Laboratory Investigation 89
  
  Pages: 98-105
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790303
[Journal Article] Reduced Level of Smoothened Suppresses Intestinal Tumorigenesis by Down-Regulation of Wnt Signaling2009
- Author(s)
  Arimura S, Matsunaga A, Kitamura T, Aoki K, Aoki M, Taketo MM.
- Journal Title
  
  Gastroenterology
  
  Volume: 137 Pages: 629-638
- Data Source
  KAKENHI-PROJECT-21229005
[Journal Article] Reduced level of Smoothened suppresses intestinal tumorigenesis by down-regulation of Wnt signaling.2009
- Author(s)
  Arimura, S., Matsunaga, A., Kitamura, T., Aoki, K., Aoki, M., Taketo, M.M.
- Journal Title
  
  Gastroenterology 137
  
  Pages: 629-638
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016032
[Journal Article] Matrix metalloproteinase 7 is required for tumor formation, but dispensable for invasion and fibrosis in SMAD4-deficient intestinal adenocarcinomas.2009
- Author(s)
  Kitamura T, Biyajima K, Aoki M, Oshima M, Taketo MM
- Journal Title
  
  Lab Invest 89(1)
  
  Pages: 98-105
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790303
[Journal Article] SMAD4-deficient intestinal tumors recruit CCR1+-myeloid cells that help invasion.2007
- Author(s)
  Kitamura, T., Kometani, K., Hashida, H., Matsunaga, A., Miyoshi, H., Hosogi, H., Aoki, M., Oshima, M., Hattori, M., Takabayashi, A., Minato, M., Taketo, M.M.
- Journal Title
  
  Nat. Genet. 39
  
  Pages: 467-475
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016032
[Journal Article] SMAD4-deficient intestinal tumors recruit CCR1+-myeloid cells that help invasion.2007
- Author(s)
  Kitamura, T, et. al.
- Journal Title
  
  Nat. Genet. 39
  
  Pages: 467-475
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016032
[Journal Article] Keeping out the bad guys: gateway to cellular target therapy.2007
- Author(s)
  Kitamura T, et. al.
- Journal Title
  
  Cancer Res. 67
  
  Pages: 10099-10102
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016032
[Journal Article] Keeping out the bad guys: gateway to cellular target therapy.2007
- Author(s)
  Kitamura, T., Taketo, M.M.
- Journal Title
  
  Cancer Res. 67
  
  Pages: 10099-10102
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016032
[Journal Article] SMAD4-deficient intestinal tumors recruit CCR1^+-myeloid cells that help invasion.2007
- Author(s)
  Kitamura, T.et al.
- Journal Title
  
  Nat.Genet. 39
  
  Pages: 467-475
- Data Source
  KAKENHI-PROJECT-17016032
[Journal Article] Keeping out the bad guys: gateway to cellular target therapy.2007
- Author(s)
  Kitamura T, et. al.
- Journal Title
  
  Cancer Res. 67
  
  Pages: 10099-10102
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209010
[Journal Article] SMAD4-deficient intestinal tumors recruit CCR1+-myeloid cells that help invasion.2007
- Author(s)
  Kitamura, T, et. al.
- Journal Title
  
  Nat. Genet. 39
  
  Pages: 467-475
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209010
[Journal Article] SMAD4-deficient intestinal tumors recruit CCR1^+-myeloid cells that help invasion.2007
- Author(s)
  Kitamura, T., et. al.
- Journal Title
  
  Nat. Genet. 125
  
  Pages: 467-4765
- Data Source
  KAKENHI-PROJECT-14GS0316
[Journal Article] Inactivation of CCR1 suppresses colon cancer liver metastasis by blocking accumulation of immature myeloid cells in a mouse model.
- Author(s)
  Kitamura T, Fujishita T, Loetscherb P, Reveszb L, Hashidac H, Kizaka-Kondohd S, Aoki M, Taketo MM
- Journal Title
  
  Proc Natl Acad Sci USA (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790303
[Presentation] The role of CCR1-expressing myeloid cells in invasion and metastasis of colon cancer cells2009
- Author(s)
  北村剛規
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸、日本
- Data Source
  KAKENHI-PROJECT-17016032
[Presentation] The role of CCR1-expressing myeloid cells in invasion and metastasis of colon cancer cells2009
- Author(s)
  北村剛規、藤下晃章、武藤誠
- Organizer
  第82回日本生化学会大会シンポジウム
- Place of Presentation
  東京
- Year and Date
  2009-10-22
- Data Source
  KAKENHI-PROJECT-20790303
[Presentation] The role of CCR1-expressing myeloid cells in invasion and metastasis of colon cancer cells2009
- Author(s)
  北村剛規
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸、日本
- Data Source
  KAKENHI-PROJECT-21229005
[Presentation] The role of CCR1-expressing myeloid cells in invasion and me tastasis of colon cancer cells2009
- Author(s)
  北村剛規
- Organizer
  第82回日本生化学会大会シンポジウム
- Place of Presentation
  神戸
- Year and Date
  2009-10-22
- Data Source
  KAKENHI-PROJECT-20790303
[Presentation] 腸癌の浸潤・転移における骨髄由来 CCR1発現細胞の役割2009
- Author(s)
  北村剛規、藤下晃章、武藤誠
- Organizer
  第10回運動器科学研究会
- Place of Presentation
  東京
- Year and Date
  2009-09-18
- Data Source
  KAKENHI-PROJECT-20790303
[Presentation] SMAD4-deficient intestinal tumors secrete CCL9, and recruit CCR1^+-immature myeloid cells that help invasion2007
- Author(s)
  北村剛規
- Organizer
  日本癌学会・学術総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-04
- Data Source
  KAKENHI-PROJECT-17016032
[Presentation] SMAD4-deficient intestinal tumors secrete CCL9, and recruit CCR1^+-immature myeloid cells that help invasion2007
- Author(s)
  北村剛規
- Organizer
  日本癌学会・学術総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-04
- Data Source
  KAKENHI-PROJECT-19209010

1. TAKETO Makoto (70281714)

# of Collaborated Projects: 5 results

# of Collaborated Products: 11 results
2. AOKI Masahiro (60362464)

# of Collaborated Projects: 5 results

# of Collaborated Products: 9 results
3. MIYOSHI Hiroyuki (30362479)

# of Collaborated Projects: 4 results

# of Collaborated Products: 1 results
4. OSHIMA Masanobu (40324610)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
5. SONOSHITA Masahiro (80511857)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
6. 石川智夫 (70322162)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 高久和明 (90313121)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. OSHIMA Hiroko (80362515)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. AOKI Koji (40402862)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
10. FUJISHITA Teruaki (50511870)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results

Kitamura Takanori 北村 剛規

KITAMURA Takanori 北村 剛規

Research Projects

Research Products

Co-Researchers

StudiesonMetastasisofDigestiveCancersUsingMouseModels

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The role of c-KIT positive cancer cells in a drug resistance of the intestinal tumorsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on digestive cancer metastasis using mouse models

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Epitehial-stromal interactions and molecularly targeted therapy

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

消化器癌の転移機構とその治療の研究

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Epithelium-stroma interactions in carcinogenesis

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Molecular mechanisms of liver metastasis2011

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Suppression of colon cancer metastasis by Aes through inhibition of Notch signaling2011

Author(s)

Journal Title

Data Source

[Journal Article] Suppression of colon cancer metastasis by Aes through inhibition of Notch signaling.2011

Author(s)

Journal Title

Data Source

[Journal Article] Inactivation of CCR1 suppresses colon cancer liver metastasis by blocking accumulation of immature myeloid cells in a mouse model.2010

Author(s)

Journal Title

Data Source

[Journal Article] Inactivation of CCR1 suppresses colon cancer liver metastasis by blocking accumulation of immature myeloid cells in a mouse model2010

Author(s)

Journal Title

Data Source

[Journal Article] Matrix metalloproteinase 7 is required for tumor formation, but dispensable for invasion and fibrosis in SMAD4-deficient intestinal adenocarcinomas.2009

Author(s)

Journal Title

Data Source

[Journal Article] Reduced level of smoothened suppresses intestinal tumorigenesis by down-regulation of Wne signaling.2009

Author(s)

Journal Title

Data Source

[Journal Article] Matrix metalloproteinase 7 is required for tumor formation, but dispensable for invasion and fibrosis in SMAD4 -deficient intestinal adenocarcinomas2009

Author(s)

Journal Title

Data Source

[Journal Article] Matrix metalloproteinase 7 is required for tumor formation, but dispensable for invasion and fibrosis in SMAD4-deficient intestinal adenocarcinomas2009

Author(s)

Journal Title

Data Source

[Journal Article] Matrix metalloproteinase 7 is required for tumor formation, but indispensable for invasion and fibrosis in SMAD4-deficient intestinal adenocarcinomas.2009

Author(s)

Kitamura Takanori 北村剛規

KITAMURA Takanori 北村剛規