Fujishita Teruaki 藤下晃章

… Alternative Names

Researcher Number	50511870
Other IDs
Affiliation (Current)	2020: 愛知県がんセンター(研究所), がん病態生理学分野, 主任研究員
Affiliation (based on the past Project Information) *help	2018 – 2020: 愛知県がんセンター(研究所), がん病態生理学分野, 主任研究員 2015 – 2017: 愛知県がんセンター(研究所), 分子病態学部, 主任研究員 2013 – 2015: 愛知県がんセンター(研究所), 分子病態学部, 研究員 2012: 京都大学, 医学(系)研究科(研究院), 助教 2012: 京都大学, 大学院・医学研究科, 助教 2011: 京都大学, 工学研究科, 助教
Review Section/Research Field	Principal Investigator Tumor biology / Experimental pathology / Basic Section 49030:Experimental pathology-related Except Principal Investigator Pathological medical chemistry / Tumor biology / Basic Section 50010:Tumor biology-related
Keywords	Principal Investigator 大腸がん / マウスモデル / 腫瘍 / がん微小環境 / 治療抵抗性 / 癌 / 遺伝子 / 薬理学 / 転移 / トランスポゾン … More Except Principal Investigator … More

大腸がん自然転移モデルを利用した転移関連遺伝子の探索Principal InvestigatorOngoing
- Principal Investigator
  
  藤下晃章
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  Aichi Cancer Center Research Institute
Molecular mechanisms and preventive/therapeutic targets of colon cancer metastasisOngoing
- Principal Investigator
  
  青木正博
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Aichi Cancer Center Research Institute
Elucidation of the interaction between tumor epithelial cells and stromal cells in acquiring resistance to molecular-targeted drugsPrincipal Investigator
- Principal Investigator
  
  FUJISHITA Teruaki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor biology
- Research Institution
  Aichi Cancer Center Research Institute
Elucidating the mechanisms of colorectal cancer metastasis using mouse models
- Principal Investigator
  
  Aoki Masahiro
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Tumor biology
- Research Institution
  Aichi Cancer Center Research Institute
The exploration of therapeutic target against colon cancer with KRAS mutationPrincipal Investigator
- Principal Investigator
  
  Fujishita Teruaki
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor biology
- Research Institution
  Aichi Cancer Center Research Institute
The role of mTOR signalng in colorectal cancerPrincipal Investigator
- Principal Investigator
  
  FUJISHITA Teruaki
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Experimental pathology
- Research Institution
  愛知県がんセンター(研究所)
  Kyoto University
StudiesonMetastasisofDigestiveCancersUsingMouseModels
- Principal Investigator
  
  TAKETO Makoto
- Project Period (FY)
  2009 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kyoto University

All 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 Other

All Journal Article Presentation Book

[Book] mTORと発がん2012
- Author(s)
  藤下晃章, 青木正博
- Total Pages
  8
- Publisher
  細胞工学
- Data Source
  KAKENHI-PROJECT-24790382
[Book] mTORと発がん.細胞工学Vol.31 No.122012
- Author(s)
  藤下晃章,青木正博
- Publisher
  秀潤社
- Data Source
  KAKENHI-PROJECT-24790382
[Book] JNKシグナル伝達経路はmTORClの活性化を介してApc^<Δ7l6>マウスにおける腸管腫療形成を促進する.日本メディカルセンター. INTESTINE Vol.16 No.052012
- Author(s)
  藤下晃章,青木正博
- Data Source
  KAKENHI-PROJECT-24790382
[Book] JNKシグナル伝達経路はmTORC1の活性化を介してApcΔ716 マウスにおける腸管腫瘍形成を促進する2012
- Author(s)
  藤下晃章, 青木正博
- Total Pages
  3
- Publisher
  INTESTINE
- Data Source
  KAKENHI-PROJECT-24790382
[Journal Article] TAZ activation by Hippo pathway dysregulation induces cytokine gene expression and promotes mesothelial cell transformation2019
- Author(s)
  Matsushita A, Sato T, Mukai S, Fujishita T, Mishiro-Sato E, Okuda M, Aoki M, Hasegawa Y, Sekido Y
- Journal Title
  
  Oncogene.
  
  Volume: 38 Pages: 1966-1978
- DOI
  10.1038/s41388-018-0417-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19628, KAKENHI-PROJECT-18K15231, KAKENHI-PLANNED-26111005, KAKENHI-PROJECT-16H04706, KAKENHI-PROJECT-18H02686, KAKENHI-PROJECT-16K07139, KAKENHI-PROJECT-17K15569
[Journal Article] Global metabolic reprogramming of colorectal cancer occurs at adenoma stage and is induced by MYC2017
- Author(s)
  Satoh K, Yachida S, Sugimoto M, Oshima M, Nakagawa T, Akamoto S, Tabata S, Saitoh K, Kato K, Sato S, Igarashi K, Aizawa Y, Kajino-Sakamoto R, Kojima Y, Fujishita T, Enomoto A, Hirayama A, Ishikawa T, Taketo MM, Kushida Y, Haba R, Okano K, Tomita M, Suzuki Y, Fukuda S, Aoki M, Soga T.
- Journal Title
  
  Proceedings of the National Academy of Sciences of the United States of America
  
  Volume: 114
- DOI
  10.1073/pnas.1710366114
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K07139, KAKENHI-PROJECT-16K21361, KAKENHI-PROJECT-26290045, KAKENHI-PUBLICLY-17H05654, KAKENHI-PLANNED-26111005, KAKENHI-PROJECT-26462860, KAKENHI-PROJECT-15K21364
[Journal Article] Tumor microenvironment confers mTOR inhibitor resistance in invasive intestinal adenocarcinoma2017
- Author(s)
  Fujishita T, Kojima Y, Kajino-Sakamoto R, Taketo MM, Aoki M.
- Journal Title
  
  Oncogene
  
  Volume: 36 Pages: 6480-6489
- DOI
  10.1038/onc.2017.242
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K07139, KAKENHI-PROJECT-26290045, KAKENHI-PLANNED-26111005
[Journal Article] Antitumor activity of the MEK inhibitor trametinib on intestinal polyp formation in Apc(Δ716) mice involves stromal COX-2.2015
- Author(s)
  Fujishita T, Kajino-Sakamoto R, Kojima Y, Taketo MM, Aoki M.
- Journal Title
  
  Cancer Science
  
  Volume: 106 Pages: 692-699
- DOI
  10.1111/cas.12670
- NAID
  120005767023
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26111005, KAKENHI-PROJECT-25253022, KAKENHI-PROJECT-26830090, KAKENHI-PROJECT-26290045
[Journal Article] CCR1-mediated accumulation of myeloid cells in the liver microenvironment promoting mouse colon cancer metastasis.2014
- Author(s)
  Hirai H, Fujishita T, Kurimoto K, Miyachi H, Kitano S, Inamoto S, Itatani Y, Saitou M, Maekawa T, Taketo MM
- Journal Title
  
  Clinical & Experimental Metastasis
  
  Volume: 31 Pages: 977-89
- DOI
  10.1007/s10585-014-9684-z
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390244, KAKENHI-PROJECT-24681039, KAKENHI-PUBLICLY-25112706, KAKENHI-PROJECT-25253022, KAKENHI-PROJECT-25461415, KAKENHI-PROJECT-25650065, KAKENHI-PROJECT-26830090
[Journal Article] Loss of SMAD4 from colorectal cancer cells promotes CCLl5 expression to recruit CCRl+myeloid cells and facilitate liver metastasis2013
- Author(s)
  Itatani Y, Kawada K, Fujishita T, Kakizaki F, Hirai H, Matsumoto T, Iwamoto M, Inamoto S, Hatano E, Hasegawa S, Maekawa T, Uemoto S, Sakai Y, Taketo MM
- Journal Title
  
  Gastroenterol ogy
  
  Volume: 145(5) Pages: 1064-1075
- DOI
  10.1053/j.gastro.2013.07.033
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390244, KAKENHI-PROJECT-24591975, KAKENHI-PROJECT-24659461, KAKENHI-PROJECT-24790382, KAKENHI-PUBLICLY-25112706, KAKENHI-PROJECT-25253022, KAKENHI-PROJECT-25430149, KAKENHI-PROJECT-25461415
[Journal Article] JNK signaling promotes intestinal tumorigenesis through mTOR complex1 activation in ApcΔ 716 mice2011
- Author(s)
  Fujishita T, Aoki M, and Taketo MM.
- Journal Title
  
  Gatroenterology
  
  Volume: 140(in press)
- Data Source
  KAKENHI-PROJECT-21229005
[Journal Article] JNK signaling promotes intestinal tumorigenesis through activation of mTOR complex 1 in Ape Δ716 mice2011
- Author(s)
  Fujishita T, Aoki M, Taketo MM
- Journal Title
  
  Gastroenterology
  
  Volume: 140 Pages: 1556-1563
- DOI
  10.1053/j.gastro.2011.02.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229005, KAKENHI-PROJECT-23300349
[Journal Article] JNK signaling promotes intestinal tumorigenesis through mTOR complex1 activation in Apc^<716> mice.2011
- Author(s)
  Fujishita T, Aoki M, Taketo MM.
- Journal Title
  
  Gastroenterology
  
  Volume: 140(In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229005
[Journal Article] Molecular mechanisms of liver metastasis.2011
- Author(s)
  Kawada K, HaSegawa S, Murakami T, Itatani Y, Hosogi H, Sonoshita M, Kitamura T, Fujishita T, Iwamoto M, Matsumoto T, Matsusue R, Hida K, Akiyaraa G, Okoshi K, Yamada M, Kawamura J, Taketo MM, Sakai Y
- Journal Title
  
  Int. J. Clin. Oncol
  
  Volume: 16 Pages: 464-472
- DOI
  10.1007/s10147-011-0307-2
- NAID
  10030246531
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229005, KAKENHI-PROJECT-22791276, KAKENHI-PROJECT-23680088
[Journal Article] Inactivation of CCR1 suppresses colon cancer liver metastasis by blocking accumulation of immature myeloid cells in a mouse model.2010
- Author(s)
  Kitamura T, Fujishita T, Loetscher P, Revesz L, Hashida H, Kizaka-Kondoh S, Aoki M, Taketo MM.
- Journal Title
  
  Proc.Natl.Acad.Sci.USA
  
  Volume: 107 Pages: 13063-13068
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229005
[Journal Article] Inactivation of CCR1 suppresses colon cancer liver metastasis by blocking accumulation of immature myeloid cells in a mouse model2010
- Author(s)
  Kitamura T, Fujishita T, Loetscher P, Revesz L, Hashida H, Kizaka-Kondoh S, Aoki M, and Taketo MM.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA
  
  Volume: 107 Pages: 13063-13068
- Data Source
  KAKENHI-PROJECT-21229005
[Journal Article] The role of mTORC1 pathway in intestinal tumorigenesis.2009
- Author(s)
  Fujishita, T., et al.
- Journal Title
  
  Cell Cycle 8
  
  Pages: 3684-3687
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229005
[Journal Article] The role of mTORC1 pathway in intestinal tumorigenesis2009
- Author(s)
  Fujishita T, Aoki M, Taketo MM.
- Journal Title
  
  Cell Cycle
  
  Volume: 8 Pages: 3684-3687
- Data Source
  KAKENHI-PROJECT-21229005
[Presentation] Apc変異マウスの腸管腫瘍形成において腸上皮細胞のMyD88が果たす役割の解明2018
- Author(s)
  梶野　リエ、藤下　晃章、武藤　誠、青木　正博
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K07139
[Presentation] 大腸がん形成におけるDio2の役割2018
- Author(s)
  小島　康、藤下　晃章、三城　恵美、梶野　リエ、武藤　誠、青木　正博
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K07139
[Presentation] Apc変異マウスの腸管腫瘍形成において腸上皮細胞のMyD88が果たす役割の解明2018
- Author(s)
  梶野リエ、藤下晃章、武藤誠、青木正博
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18H02686
[Presentation] 大腸がんのmTOR阻害薬抵抗性獲得にヒスタミンが関与している2018
- Author(s)
  藤下晃章
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18H02686
[Presentation] 大腸がんのmTOR阻害薬抵抗性獲得にヒスタミンが関与している2018
- Author(s)
  藤下　晃章、小島　康、三城　恵美、曽我　朋義、武藤　誠、青木　正博
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K07139
[Presentation] 浸潤性腸がんのmTOR阻害薬抵抗性獲得にはがん微小環境が関与する2017
- Author(s)
  青木正博、藤下晃章
- Organizer
  第21回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-26290045
[Presentation] Combination treatment with erlotinib and trametinib suppresses intestinal adenocarcinoma formation in cis- Apc/Smad4 mice2017
- Author(s)
  津田都子、藤下晃章、小島康、武藤誠、青木正博
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K07139
[Presentation] 腸管腫瘍の薬剤抵抗性獲得におけるEGF受容体の役割2017
- Author(s)
  藤下晃章，津田都子、小島康、武藤誠、青木正博
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-26290045
[Presentation] Apc+/Δ716マウスの腸管腫瘍形成において腸上皮細胞のMyD88が果たす役割の解析2017
- Author(s)
  梶野リエ、藤下晃章、武藤誠、青木正博
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-26290045
[Presentation] がん微小環境は浸潤性大腸がんにmTOR阻害薬抵抗性をもたらす2017
- Author(s)
  藤下晃章
- Organizer
  次世代を担う創薬・医療薬理シンポジウム2017
- Data Source
  KAKENHI-PROJECT-26290045
[Presentation] Role of intestinal epithelial MyD88 in intestinal tumorigenesis in Apc mice2017
- Author(s)
  梶野リエ、藤下晃章、武藤誠、青木正博
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K07139
[Presentation] エルロチニブとトラメチニブの併用投与はcis-Apc/Smad4マウスの腸管腺がん形成を抑制する2017
- Author(s)
  津田都子、藤下晃章、小島康、武藤誠、青木正博
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-26290045
[Presentation] Roles of EGFR activation in drug resistance of intestinal tumors2017
- Author(s)
  藤下晃章、津田都子、小島康、武藤誠、青木正博
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K07139
[Presentation] Role of Deiodinase, lodothyronine, TypeIIin Colon Tumorigenesis2016
- Author(s)
  小島康、今度ゆり子、藤下晃章、梶野リエ、武藤誠、青木正博
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-16K07139
[Presentation] MEK阻害剤trametinibによる間質を介した腸管腫瘍形成抑制およびmTOR阻害薬耐性の回避2016
- Author(s)
  青木正博、藤下晃章
- Organizer
  第68回日本細胞生物学会大会
- Place of Presentation
  京都テルサ（京都府・京都市）
- Data Source
  KAKENHI-PROJECT-26290045
[Presentation] II型脱ヨード酵素の大腸がん進展における役割2016
- Author(s)
  小島康、今度ゆりこ、藤下晃章、梶野リエ、武藤誠、青木正博
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Data Source
  KAKENHI-PROJECT-26290045
[Presentation] がん微小環境は浸潤性腸がんのmTOR阻害薬抵抗性獲得に関与する2016
- Author(s)
  藤下晃章、梶野リエ、小島康、武藤誠、青木正博
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Data Source
  KAKENHI-PROJECT-26290045
[Presentation] Tumor microenvironment confers mTOR inhibitor resistance to invasive intestinal adenocarcinoma2016
- Author(s)
  藤下晃章、梶野リエ、小島康、武藤誠、青木正博
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-16K07139
[Presentation] 腸管腫瘍形成における JNK-mTORC1 経路活性化と神経伝達物質の関連の解明2016
- Author(s)
  梶野リエ、藤下晃章、武藤誠、青木正博
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Data Source
  KAKENHI-PROJECT-26290045
[Presentation] Elucidation of the relevance of JNK-mTORC1 pathway activation to neuropeptides during intestinal tumorigenesis2016
- Author(s)
  梶野リエ、藤下晃章、武藤誠、青木正博
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-16K07139
[Presentation] 腸管腫瘍形成におけるJNK-mTORC1経路活性化機序の解析2015
- Author(s)
  梶野リエ、藤下晃章、小島康、武藤誠、青木正博
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（名古屋市）
- Year and Date
  2015-10-10
- Data Source
  KAKENHI-PROJECT-26830090
[Presentation] II 型脱ヨード酵素の大腸がん進展における役割の検討2015
- Author(s)
  小島康、藤下晃章、武藤誠、青木正博
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（名古屋市）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26830090
[Presentation] MEK/ERK経路の阻害はCOX2およびCCL2の発言レベルを減少させ腸管ポリープ形成を抑制する2015
- Author(s)
  藤下晃章、梶野リエ、小島康、武藤誠、青木正博
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知県・名古屋市）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26290045
[Presentation] 腸管腫瘍形成における甲状腺ホルモンの役割2015
- Author(s)
  小島康, オリムフローレンス, 藤下晃章, 武藤誠, 青木正博
- Organizer
  第38回分子生物学会年会
- Place of Presentation
  神戸ポートアイランド（神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26830090
[Presentation] II型脱ヨード酵素の大腸がん進展における役割の検討2015
- Author(s)
  小島康、藤下晃章、武藤誠、青木正博
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知県・名古屋市）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26290045
[Presentation] MEK/ERK 経路の阻害はCOX2およびCCL2の発現レベルを減少させ腸管ポリープ形成を抑制する2015
- Author(s)
  藤下晃章、梶野リエ、小島康、武藤誠、青木正博
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（名古屋市）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26830090
[Presentation] 腸管腫瘍形成におけるJNK-mTORC1経路活性化機序の解析2015
- Author(s)
  梶野リエ、藤下晃章、小島康、武藤誠、青木正博
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知県・名古屋市）
- Year and Date
  2015-10-10
- Data Source
  KAKENHI-PROJECT-26290045
[Presentation] マウスモデルを用いた大腸がん浸潤･転移の予防･治療標的の探索2015
- Author(s)
  青木正博、藤下晃章、武藤誠
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知県・名古屋市）
- Year and Date
  2015-10-08
- Invited
- Data Source
  KAKENHI-PROJECT-26290045
[Presentation] 腸管腫瘍形成における甲状腺ホルモンの役割2015
- Author(s)
  小島康、オリム・フローレンス、藤下晃章、武藤誠、青木正博
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド（兵庫県・神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26290045
[Presentation] MEK阻害薬trametinibによるAｐｃ△716マウスの腸管ポリープ形成抑制効果と間質COX-2の関与2015
- Author(s)
  青木正博、武藤誠、藤下晃章
- Organizer
  第19回日本分子標的治療学会学術集会
- Place of Presentation
  松山全日空ホテル（愛媛県・松山市）
- Year and Date
  2015-06-11
- Data Source
  KAKENHI-PROJECT-26290045
[Presentation] 腸管腫瘍形成における JNK-mTORC1 経路活性化機序の解析2014
- Author(s)
  梶野　リエ、藤下晃章、小島　康、武藤　誠、青木　正博
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(横浜市)
- Year and Date
  2014-09-27
- Data Source
  KAKENHI-PROJECT-26290045
[Presentation] Simultaneous inhibition of mTOR and EGFR suppresses local invasion of intestinal adenocarcinoma in　cis-Apc+/Δ716/Smad4 mice2014
- Author(s)
  Teruaki Fujishita, Makoto M. Taketo, Masahiro Aoki
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Year and Date
  2014-11-25
- Data Source
  KAKENHI-PROJECT-26830090
[Presentation] MEK阻害薬トラメチニブによる Apc 変異マウスの腸管ポリープ形成抑制効果2014
- Author(s)
  青木正博、梶野リエ、武藤誠、藤下晃章
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(横浜市)
- Year and Date
  2014-09-25
- Data Source
  KAKENHI-PROJECT-26290045
[Presentation] EGF受容体の活性化は大腸がんモデルマウスの大腸がんにmTORキナーゼ阻害薬に対する耐性をもたらす2014
- Author(s)
  藤下晃章, 小島康, 梶野リエ, 武藤誠, 青木正博
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Year and Date
  2014-09-26
- Data Source
  KAKENHI-PROJECT-26830090
[Presentation] MEK阻害薬トラメチニブによるApc変異マウスの腸管ポリープ形成抑制効果2014
- Author(s)
  青木正博, 小島康, 梶野リエ, 武藤誠, 藤下晃章
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Year and Date
  2014-09-25
- Data Source
  KAKENHI-PROJECT-26830090
[Presentation] Apc+/Δ716マウスの腸管腫瘍におけるJNK-mTORC1経路活性化機序の解析2014
- Author(s)
  梶野　リエ、藤下晃章、小島　康、武藤　誠、青木　正博
- Organizer
  第37会日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(横浜市)
- Year and Date
  2014-11-25
- Data Source
  KAKENHI-PROJECT-26290045
[Presentation] Simultaneous inhibition of mTOR and EGFR suppresses local invasion in intestinal adenocarcinoma in cis-ApcΔ716/Smad4 mice.2014
- Author(s)
  青木正博、武藤　誠、藤下晃章
- Organizer
  第37会日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(横浜市)
- Year and Date
  2014-11-25
- Data Source
  KAKENHI-PROJECT-26290045
[Presentation] Apc+/Δ716マウスの腸管腫瘍におけるJNK-mTORC 1経路活性化機序の解析2014
- Author(s)
  梶野リエ, 藤下晃章, 小島康, 武藤誠, 青木正博
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Year and Date
  2014-11-25
- Data Source
  KAKENHI-PROJECT-26830090
[Presentation] 腸管腫瘍形成におけるJNK-mTORC１経路活性化機序の解析2014
- Author(s)
  梶野リエ, 藤下晃章, 小島康, 武藤誠, 青木正博
- Organizer
  第73日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Year and Date
  2014-09-27
- Data Source
  KAKENHI-PROJECT-26830090
[Presentation] EGF受容体の活性化は大腸がんモデルマウスの大腸がんに mTORキナーゼ阻害薬に対する耐性をもたらす2014
- Author(s)
  藤下晃章、武藤　誠、青木　正博
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(横浜市)
- Year and Date
  2014-09-26
- Data Source
  KAKENHI-PROJECT-26290045
[Presentation] The mTOR kinase inhibitor AZD8055 suppresses the expansion of intestinal adenocarcinoma in cis Apc/Smad4 mice2013
- Author(s)
  藤下晃章,武藤誠,青木正博
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(横浜市)
- Year and Date
  2013-10-04
- Data Source
  KAKENHI-PROJECT-24790382
[Presentation] Suppression of intestinal adenocarcinoma formation in cis Apc/Smad4 mice by the mTOR kinase inhibitor AZD80552013
- Author(s)
  藤下晃章,武藤誠,青木正博
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド(神戸市)
- Year and Date
  2013-12-05
- Data Source
  KAKENHI-PROJECT-24790382
[Presentation] INK signaling promotes intestinal tumorigenesis through mTORC1 pathway activation in ApeΔ716 mice2012
- Author(s)
  藤下晃章, 青木正博, 武藤誠
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  京都国際会館
- Year and Date
  2012-03-14
- Data Source
  KAKENHI-PROJECT-21229005
[Presentation] JNK promotes intestinal tumor formation in mutant mice through activation of mTOR couplex 12011
- Author(s)
  青木正博, 藤下晃章、武藤誠
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋コングレスセンター
- Year and Date
  2011-10-04
- Data Source
  KAKENHI-PROJECT-21229005
[Presentation] JNKシグナル伝達経路はmTORC1の活性化を介してApe変異マウスの腸管腫瘍形成を促進する2011
- Author(s)
  青木正博, 藤下晃章、武藤誠
- Organizer
  第15回日本がん分子標的治療学会学術集会
- Place of Presentation
  ホテル日航東京
- Year and Date
  2011-06-23
- Data Source
  KAKENHI-PROJECT-21229005
[Presentation] The roles of mTORC1 in the intestinal adenocarcinoma2011
- Author(s)
  藤下晃章、青木正博, 武藤誠
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋コングレスセンター
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-21229005
[Presentation] JNK signaling promotes intestinal tumorigenesis through mTOR complex 1 activation in ApcΔ716 mice2010
- Author(s)
  藤下晃章
- Organizer
  第69回日本癌学会・学術総会
- Place of Presentation
  大阪
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-21229005
[Presentation] JNK signaling promotes intestinal tumorigenesis through mTORC1 pathway activation in ApcΔ716 mice"2010
- Author(s)
  藤下晃章
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-21229005
[Presentation] JNK signaling promotes intestinal tumorigenesis through mTORC1 pathway activation in ApcΔ^<716> mice2010
- Author(s)
  藤下晃章
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会
- Place of Presentation
  神戸、日本
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-21229005
[Presentation] JNK signaling promotes intestinal tumorigenesis through mTOR complex 1 activation in ApcΔ^<716> mice2010
- Author(s)
  藤下晃章
- Organizer
  第69回日本癌学会・学術総会
- Place of Presentation
  大阪、日本
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-21229005
[Presentation] The mTOR kinase inhibitor AZD8055 suppresses the expansion of intestinal adenocarcinoma in cis-Apc/Smad4 mice.
- Author(s)
  藤下晃章、武藤誠、青木正博
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜 (横浜市)
- Data Source
  KAKENHI-PROJECT-24790382
[Presentation] Suppression of intestinal adenocarcinoma formation in cis-Apc/Smad4 mice by the mTOR kinase inhibitor AZD8055.
- Author(s)
  藤下晃章、武藤誠、青木正博
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド　神戸国際展示場 (神戸市)
- Data Source
  KAKENHI-PROJECT-24790382

1. AOKI Masahiro (60362464)

# of Collaborated Projects: 3 results

# of Collaborated Products: 34 results
2. 梶野リエ (20633184)

# of Collaborated Projects: 2 results

# of Collaborated Products: 13 results
3. 小島康 (30464217)

# of Collaborated Projects: 2 results

# of Collaborated Products: 13 results
4. 佐久間圭一朗 (90402891)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. TAKETO Makoto (70281714)

# of Collaborated Projects: 1 results

# of Collaborated Products: 14 results
6. KITAMURA Takanori (10378622)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
7. SONOSHITA Masahiro (80511857)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. AOKI Koji (40402862)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
9. TAKEDA Junji (50163407)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 三城恵美 (00455544)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. SUGIMOTO Masahiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. HIRAYAMA Akiyoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. TATSUHIRO Sato

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 前川平

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
15. 平位秀世

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
16. 河田健二

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
17. 柿崎文彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 田畑祥

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 福田真嗣

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 栗本一基

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 関戸好孝

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 向井智美

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Fujishita Teruaki 藤下 晃章

FUJISHITA Teruaki 藤下 晃章

Research Projects

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Co-Researchers

大腸がん自然転移モデルを利用した転移関連遺伝子の探索Principal InvestigatorOngoing

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Molecular mechanisms and preventive/therapeutic targets of colon cancer metastasisOngoing

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Elucidation of the interaction between tumor epithelial cells and stromal cells in acquiring resistance to molecular-targeted drugsPrincipal Investigator

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Elucidating the mechanisms of colorectal cancer metastasis using mouse models

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The exploration of therapeutic target against colon cancer with KRAS mutationPrincipal Investigator

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The role of mTOR signalng in colorectal cancerPrincipal Investigator

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StudiesonMetastasisofDigestiveCancersUsingMouseModels

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[Book] mTORと発がん2012

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[Book] mTORと発がん.細胞工学Vol.31 No.122012

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[Book] JNKシグナル伝達経路はmTORClの活性化を介してApc^<Δ7l6>マウスにおける腸管腫療形成を促進する.日本メディカルセンター. INTESTINE Vol.16 No.052012

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[Book] JNKシグナル伝達経路はmTORC1の活性化を介してApcΔ716 マウスにおける腸管腫瘍形成を促進する2012

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[Journal Article] TAZ activation by Hippo pathway dysregulation induces cytokine gene expression and promotes mesothelial cell transformation2019

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[Journal Article] Global metabolic reprogramming of colorectal cancer occurs at adenoma stage and is induced by MYC2017

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[Journal Article] Tumor microenvironment confers mTOR inhibitor resistance in invasive intestinal adenocarcinoma2017

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[Journal Article] Antitumor activity of the MEK inhibitor trametinib on intestinal polyp formation in Apc(Δ716) mice involves stromal COX-2.2015

Fujishita Teruaki 藤下晃章

FUJISHITA Teruaki 藤下晃章