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Kajino Rie  梶野 リエ

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KAJINO Rie  梶野 リエ

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Researcher Number 20633184
Other IDs
Affiliation (Current) 2020: 愛知県がんセンター(研究所), がん病態生理学分野, 研究員
Affiliation (based on the past Project Information) *help 2018 – 2020: 愛知県がんセンター(研究所), がん病態生理学分野, 研究員
2017: 愛知県がんセンター(研究所), 分子病態学部`, 研究員
2012 – 2016: 愛知県がんセンター(研究所), 分子病態学部, 研究員
Review Section/Research Field
Principal Investigator
Tumor biology / Tumor biology / Basic Section 50010:Tumor biology-related
Except Principal Investigator
Tumor biology / Basic Section 50010:Tumor biology-related
Keywords
Principal Investigator
免疫学 / 大腸がん / 癌 / シグナル伝達 / 免疫 / 神経 / Apc変異 / 合成致死 / マウスモデル
Except Principal Investigator
大腸がん … More / 転移 / マウスモデル / スプライシング / RNA結合タンパク / トランスポゾン / 遺伝子改変マウス / 動物実験 / 上皮間葉転換 / マルチオミクス解析 / プロテオーム解析 Less
  • Research Projects

    (5 results)
  • Research Products

    (22 results)
  • Co-Researchers

    (11 People)
  •  Apc変異腸管腫瘍におけるMyD88経路の役割解明と治療標的の探索Principal InvestigatorOngoing

    • Principal Investigator
      梶野 リエ
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50010:Tumor biology-related
    • Research Institution
      Aichi Cancer Center Research Institute
  •  Molecular mechanisms and preventive/therapeutic targets of colon cancer metastasisOngoing

    • Principal Investigator
      青木 正博
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 50010:Tumor biology-related
    • Research Institution
      Aichi Cancer Center Research Institute
  •  Elucidating the mechanisms of colorectal cancer metastasis using mouse models

    • Principal Investigator
      Aoki Masahiro
    • Project Period (FY)
      2014 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Tumor biology
    • Research Institution
      Aichi Cancer Center Research Institute
  •  Analysis of the role of nervous and immune system interactions in development of colon cancerPrincipal Investigator

    • Principal Investigator
      Kajino Rie
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Tumor biology
    • Research Institution
      Aichi Cancer Center Research Institute
  •  Analysis of the role of immune system in intestinal carcinogenesis and metastasis using a mouse modelPrincipal Investigator

    • Principal Investigator
      KAJINO Rie
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Research Field
      Tumor biology
    • Research Institution
      愛知県がんセンター(研究所)

All 2019 2018 2017 2016 2015 2014

All Journal Article Presentation

  • [Journal Article] Stromal Iodothyronine Deiodinase 2 (DIO2) Promotes the Growth of Intestinal Tumors in Apc Δ716 Mutant Mice2019

    • Author(s)
      Kojima Yasushi、Kondo Yuriko、Fujishita Teruaki、Mishiro‐Sato Emi、Kajino‐Sakamoto Rie、Taketo Makoto Mark、Aoki Masahiro
    • Journal Title

      Cancer Science

      Volume: 110 Pages: 2520-2528

    • DOI

      10.1111/cas.14100

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H02686, KAKENHI-PROJECT-17K07191
  • [Journal Article] Global metabolic reprogramming of colorectal cancer occurs at adenoma stage and is induced by MYC2017

    • Author(s)
      Satoh K, Yachida S, Sugimoto M, Oshima M, Nakagawa T, Akamoto S, Tabata S, Saitoh K, Kato K, Sato S, Igarashi K, Aizawa Y, Kajino-Sakamoto R, Kojima Y, Fujishita T, Enomoto A, Hirayama A, Ishikawa T, Taketo MM, Kushida Y, Haba R, Okano K, Tomita M, Suzuki Y, Fukuda S, Aoki M, Soga T.
    • Journal Title

      Proceedings of the National Academy of Sciences of the United States of America

      Volume: 114

    • DOI

      10.1073/pnas.1710366114

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K07139, KAKENHI-PROJECT-16K21361, KAKENHI-PROJECT-26290045, KAKENHI-PUBLICLY-17H05654, KAKENHI-PLANNED-26111005, KAKENHI-PROJECT-26462860, KAKENHI-PROJECT-15K21364
  • [Journal Article] Tumor microenvironment confers mTOR inhibitor resistance in invasive intestinal adenocarcinoma2017

    • Author(s)
      Fujishita T, Kojima Y, Kajino-Sakamoto R, Taketo MM, Aoki M.
    • Journal Title

      Oncogene

      Volume: 36 Pages: 6480-6489

    • DOI

      10.1038/onc.2017.242

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K07139, KAKENHI-PROJECT-26290045, KAKENHI-PLANNED-26111005
  • [Journal Article] Antitumor activity of the MEK inhibitor trametinib on intestinal polyp formation in Apc(Δ716) mice involves stromal COX-2.2015

    • Author(s)
      Fujishita T, Kajino-Sakamoto R, Kojima Y, Taketo MM, Aoki M.
    • Journal Title

      Cancer Science

      Volume: 106 Pages: 692-699

    • DOI

      10.1111/cas.12670

    • NAID

      120005767023

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111005, KAKENHI-PROJECT-25253022, KAKENHI-PROJECT-26830090, KAKENHI-PROJECT-26290045
  • [Presentation] 腸管腫瘍形成におけるDio2(2 型脱ヨード酵素)の生物学的役割2019

    • Author(s)
      小島 康、藤下晃章、梶野リエ、三城恵美、武藤 誠、青木正博
    • Organizer
      第78回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-18H02686
  • [Presentation] MyD88 によるApc 変異腸上皮細胞の合成致死メカニズムの解明2019

    • Author(s)
      梶野リエ、藤下晃章、武藤 誠、青木正博
    • Organizer
      第78回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-18H02686
  • [Presentation] Synthetic lethality between Apc mutation and MyD88 loss in intestinal tumor epithelial cells2019

    • Author(s)
      梶野リエ、藤下晃章、武藤誠、青木正博
    • Organizer
      第78回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K07254
  • [Presentation] Apc変異マウスの腸管腫瘍形成において腸上皮細胞のMyD88が果たす役割の解明2018

    • Author(s)
      梶野リエ、藤下晃章、武藤誠、青木正博
    • Organizer
      第77回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K07254
  • [Presentation] Apc変異マウスの腸管腫瘍形成において腸上皮細胞のMyD88が果たす役割の解明2018

    • Author(s)
      梶野リエ、藤下晃章、武藤誠、青木正博
    • Organizer
      第77回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-18H02686
  • [Presentation] Apc+/Δ716マウスの腸管腫瘍形成において腸上皮細胞のMyD88が果たす役割の解析2017

    • Author(s)
      梶野リエ、藤下晃章、武藤誠、青木正博
    • Organizer
      第76回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-26290045
  • [Presentation] がん微小環境は浸潤性腸がんのmTOR阻害薬抵抗性獲得に関与する2016

    • Author(s)
      藤下晃章、梶野リエ、小島康、武藤誠、青木正博
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Data Source
      KAKENHI-PROJECT-26290045
  • [Presentation] II型脱ヨード酵素の大腸がん進展における役割2016

    • Author(s)
      小島康、今度ゆりこ、藤下晃章、梶野リエ、武藤誠、青木正博
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Data Source
      KAKENHI-PROJECT-26290045
  • [Presentation] 腸管腫瘍形成における JNK-mTORC1 経路活性化と神経伝達物質の関連の解明2016

    • Author(s)
      梶野リエ、藤下晃章、武藤誠、青木正博
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Data Source
      KAKENHI-PROJECT-26290045
  • [Presentation] 大腸がんマウスモデルとオルガノイド 培養を用いた腫瘍形成における低酸素 シグナルの役割の解明2016

    • Author(s)
      梶野リエ、青木正博
    • Organizer
      第14回がんとハイポキシア研究会
    • Place of Presentation
      岐阜グランドホテル(岐阜県・岐阜市)
    • Data Source
      KAKENHI-PROJECT-26290045
  • [Presentation] 腸管腫瘍形成におけるJNK-mTORC1経路活性化機序の解析2015

    • Author(s)
      梶野リエ、藤下晃章、小島康、武藤誠、青木正博
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場(愛知県・名古屋市)
    • Year and Date
      2015-10-10
    • Data Source
      KAKENHI-PROJECT-26290045
  • [Presentation] MEK/ERK経路の阻害はCOX2およびCCL2の発言レベルを減少させ腸管ポリープ形成を抑制する2015

    • Author(s)
      藤下晃章、梶野リエ、小島康、武藤誠、青木正博
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場(愛知県・名古屋市)
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-26290045
  • [Presentation] Analysis of the mechanisms of JNK-mTORC1 pathway activation during intestinal tumorigenesis2015

    • Author(s)
      梶野リエ
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場(名古屋市)
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-26830091
  • [Presentation] MEK阻害薬トラメチニブによる Apc 変異マウスの腸管ポリープ形成抑制効果2014

    • Author(s)
      青木正博、梶野リエ、武藤誠、藤下晃章
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Year and Date
      2014-09-25
    • Data Source
      KAKENHI-PROJECT-26290045
  • [Presentation] Apc+/Δ716マウスの腸管腫瘍におけるJNK-mTORC1経路活性化機序の解析2014

    • Author(s)
      梶野 リエ、藤下 晃章、小島 康、武藤 誠、青木 正博
    • Organizer
      第37会日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Year and Date
      2014-11-25
    • Data Source
      KAKENHI-PROJECT-26290045
  • [Presentation] Apc+/Δ716マウスの腸管腫瘍におけるJNK-mTORC1経路活性化機序の解析2014

    • Author(s)
      梶野リエ
    • Organizer
      第37回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Year and Date
      2014-11-25
    • Data Source
      KAKENHI-PROJECT-26830091
  • [Presentation] 腸管腫瘍形成におけるJNK-mTORC1経路活性化機序の解析2014

    • Author(s)
      梶野リエ
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Year and Date
      2014-09-27
    • Data Source
      KAKENHI-PROJECT-26830091
  • [Presentation] 腸管腫瘍形成における JNK-mTORC1 経路活性化機序の解析2014

    • Author(s)
      梶野 リエ、藤下 晃章、小島 康、武藤 誠、青木 正博
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Year and Date
      2014-09-27
    • Data Source
      KAKENHI-PROJECT-26290045
  • 1.  Aoki Masahiro (60362464)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 17 results
  • 2.  小島 康 (30464217)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 11 results
  • 3.  藤下 晃章 (50511870)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 16 results
  • 4.  佐久間 圭一朗 (90402891)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  TAKEDA Junji (50163407)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  三城 恵美 (00455544)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 7.  TABATA Sho
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 8.  SUGIMOTO Masahiro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 9.  HIRAYAMA Akiyoshi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 10.  武藤 誠
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 11.  福田 真嗣
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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