KOJIMA Yasushi 小島康

Researcher Number	30464217
Other IDs
Affiliation (Current)	2025: 愛知県がんセンター(研究所), がん病態生理学分野, 主任研究員
Affiliation (based on the past Project Information) *help	2018 – 2025: 愛知県がんセンター(研究所), がん病態生理学分野, 主任研究員 2011 – 2017: 愛知県がんセンター(研究所), 分子病態学部, 主任研究員 2013: 愛知県がんセンター(研究所), 分子病態学部, 主任研究員
Review Section/Research Field	Principal Investigator Tumor biology / Basic Section 59040:Nutrition science and health science-related / Basic Section 50010:Tumor biology-related / Tumor biology Except Principal Investigator Basic Section 50010:Tumor biology-related / Tumor biology / Tumor biology
Keywords	Principal Investigator 大腸がん / がん悪液質 / リソソーム / 小胞体 / 肝臓 / プロテオミクス / がん / 悪液質 / NAD / ビタミンB … More / がん微小環境 / 遺伝子改変動物 / 腫瘍血管 / 大腸 / DIO2 / 甲状腺 / 実験動物 / Wnt / 大腸癌 / 腫瘍生物学 / 核ラミナ / 核膜孔複合体 … More Except Principal Investigator 大腸がん / 転移 / マウスモデル / がん幹細胞 / スプライシング / 未分化性 / プロテオーム解析 / マルチオミクス解析 / 上皮間葉転換 / 動物実験 / 遺伝子改変マウス / トランスポゾン / RNA結合タンパク / shRNAライブラリー / shRNA Less

Molecular mechanisms maintaining the undifferntiated state of colorectal cancer stem cells
- Principal Investigator
  
  青木正博
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Aichi Cancer Center Research Institute
がん悪液質の病態生理解明Principal Investigator
- Principal Investigator
  
  小島康
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Aichi Cancer Center Research Institute
Molecular mechanisms that maintain stemness in metastatic colorectal cancer
- Principal Investigator
  
  青木正博
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Aichi Cancer Center Research Institute
Elucidating the pathophysiology of cancer cachexiaPrincipal Investigator
- Principal Investigator
  
  Kojima Yasushi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Aichi Cancer Center Research Institute
Molecular mechanisms and preventive/therapeutic targets of colon cancer metastasis
- Principal Investigator
  
  AOKI MASAHIRO
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Aichi Cancer Center Research Institute
Roles of Dio2 (deiodinase, iodothyronine, type II) in colorectal tumorigenesisPrincipal Investigator
- Principal Investigator
  
  Kojima Yasushi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor biology
- Research Institution
  Aichi Cancer Center Research Institute
Generation of a genetically engineered mouse model that reproducibly develops tumors in the large intestinePrincipal Investigator
- Principal Investigator
  
  Kojima Yasushi
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Tumor biology
- Research Institution
  Aichi Cancer Center Research Institute
Elucidating the mechanisms of colorectal cancer metastasis using mouse models
- Principal Investigator
  
  Aoki Masahiro
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Tumor biology
- Research Institution
  Aichi Cancer Center Research Institute
Development of in vivo screening systems for cancer metastasis suppressors
- Principal Investigator
  
  AOKI MASAHIRO
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Tumor biology
- Research Institution
  愛知県がんセンター(研究所)
Roles of nuclear pore complex and lamina in intestinal tumor formationPrincipal Investigator
- Principal Investigator
  
  KOJIMA Yasushi
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Tumor biology
- Research Institution
  Aichi Cancer Center Research Institute

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013

All Journal Article Presentation

[Journal Article] がん悪液質に伴う代謝臓器変容のマルチオミクス解析2024
- Author(s)
  青木正博　小島康
- Volume
  42
- Pages
  528
- DOI
  10.18958/7427-00001-0001354-00
- Language
  Japanese
- Data Source
  KAKENHI-PROJECT-21K07140
[Journal Article] Decreased liver B vitamin-related enzymes as a metabolic hallmark of cancer cachexia2023
- Author(s)
  Kojima Yasushi、Mishiro-Sato Emi、Fujishita Teruaki、Satoh Kiyotoshi、Kajino-Sakamoto Rie、Oze Isao、Nozawa Kazuki、Narita Yukiya、Ogata Takatsugu、Matsuo Keitaro、Muro Kei、Taketo Makoto Mark、Soga Tomoyoshi、Aoki Masahiro
- Journal Title
  
  Nature Communications
  
  Volume: 14 Issue: 1 Pages: 1-23
- DOI
  10.1038/s41467-023-41952-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K06624, KAKENHI-PROJECT-21K07140, KAKENHI-ORGANIZER-23H04939, KAKENHI-PROJECT-22H04923, KAKENHI-PROJECT-23K24170
[Journal Article] L-2hydroxyglutaric acid rewires amino acid metabolism in colorectal cancer via the mTOR-ATF4 axis2023
- Author(s)
  Tabata Sho、Kojima Yasushi、Sakamoto Takeharu、Igarashi Kaori、Umetsu Ko、Ishikawa Takamasa、Hirayama Akiyoshi、Kajino-Sakamoto Rie、Sakamoto Naoya、Yasumoto Ken-ichi、Okano Keiichi、Suzuki Yasuyuki、Yachida Shinichi、Aoki Masahiro、Soga Tomoyoshi
- Journal Title
  
  Oncogene
  
  Volume: 42 Issue: 16 Pages: 1294-1307
- DOI
  10.1038/s41388-023-02632-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07150, KAKENHI-PROJECT-19K07659, KAKENHI-PROJECT-17KK0199, KAKENHI-PROJECT-22K19464, KAKENHI-ORGANIZER-23H04939, KAKENHI-PROJECT-23K24170, KAKENHI-PROJECT-23K28008
[Journal Article] TGF‐β signaling promotes desmoid tumor formation via CSRP2 upregulation2023
- Author(s)
  Li Yu、Fujishita Teruaki、Mishiro‐Sato Emi、Kojima Yasushi、Niu Yanqing、Taketo Makoto Mark、Urano Yuya、Sakai Tomohisa、Enomoto Atsushi、Nishida Yoshihiro、Aoki Masahiro
- Journal Title
  
  Cancer Science
  
  Volume: 115 Issue: 2 Pages: 401-411
- DOI
  10.1111/cas.16037
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K06624, KAKENHI-PROJECT-23K24170
[Journal Article] The cAMP/PKA/CREB and TGFβ/SMAD4 Pathways Regulate Stemness and Metastatic Potential in Colorectal Cancer Cells2022
- Author(s)
  Fujishita Teruaki、Kojima Yasushi、Kajino-Sakamoto Rie、Mishiro-Sato Emi、Shimizu Yasuhiro、Hosoda Waki、Yamaguchi Rui、Taketo Makoto Mark、Aoki Masahiro
- Journal Title
  
  Cancer Research
  
  Volume: 82 Issue: 22 Pages: 4179-4190
- DOI
  10.1158/0008-5472.can-22-1369
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K19456, KAKENHI-PROJECT-20K07440, KAKENHI-PROJECT-23K24170, KAKENHI-PROJECT-22H04923
[Journal Article] Experimental Animal Model of Re-irradiation to Evaluate Radiation-induced Damage in the Normal Intestine2020
- Author(s)
  Hiroshi Doi , Mikoto Tamura , Kiyoshi Nakamatsu , Hajime Monzen , Yasumasa Nishimura
- Journal Title
  
  Anticancer Res
  
  Volume: 40(4) Issue: 12 Pages: 1981-1988
- DOI
  10.1038/s41417-020-00282-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08135, KAKENHI-PROJECT-20K07623, KAKENHI-PROJECT-18H02686, KAKENHI-PROJECT-18K09012, KAKENHI-PROJECT-20K07440, KAKENHI-PROJECT-20K09378
[Journal Article] Stromal iodothyronine deiodinase 2 ( DIO 2) promotes the growth of intestinal tumors in Apc Δ716 mutant mice2019
- Author(s)
  Kojima Yasushi、Kondo Yuriko、Fujishita Teruaki、Mishiro‐Sato Emi、Kajino‐Sakamoto Rie、Taketo Makoto Mark、Aoki Masahiro
- Journal Title
  
  Cancer Science
  
  Volume: 110 Issue: 8 Pages: 2520-2528
- DOI
  10.1111/cas.14100
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02686, KAKENHI-PROJECT-17K07191
[Journal Article] Tumor microenvironment confers mTOR inhibitor resistance in invasive intestinal adenocarcinoma2017
- Author(s)
  Fujishita T, Kojima Y, Kajino-Sakamoto R, Taketo MM, Aoki M.
- Journal Title
  
  Oncogene
  
  Volume: 36 Issue: 46 Pages: 6480-6489
- DOI
  10.1038/onc.2017.242
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K07139, KAKENHI-PROJECT-26290045, KAKENHI-PLANNED-26111005
[Journal Article] Global metabolic reprogramming of colorectal cancer occurs at adenoma stage and is induced by MYC2017
- Author(s)
  Satoh K, Yachida S, Sugimoto M, Oshima M, Nakagawa T, Akamoto S, Tabata S, Saitoh K, Kato K, Sato S, Igarashi K, Aizawa Y, Kajino-Sakamoto R, Kojima Y, Fujishita T, Enomoto A, Hirayama A, Ishikawa T, Taketo MM, Kushida Y, Haba R, Okano K, Tomita M, Suzuki Y, Fukuda S, Aoki M, Soga T.
- Journal Title
  
  Proc Natl Acad Sci U S A
  
  Volume: 114 Issue: 37
- DOI
  10.1073/pnas.1710366114
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K07139, KAKENHI-PROJECT-16K21361, KAKENHI-PROJECT-26290045, KAKENHI-PUBLICLY-17H05654, KAKENHI-PLANNED-26111005, KAKENHI-PROJECT-26462860, KAKENHI-PROJECT-15K21364
[Journal Article] Association between and polymorphisms and adverse drug reactions to regorafenib: A preliminary study2017
- Author(s)
  Maeda A, Ando H, Ura T, Komori A, Hasegawa A, Taniguchi H, Kadowaki S, Muro K, Tajika M, Kobara M, Matsuzaki M, Hashimoto N, Maeda M, Kojima Y, Aoki M, Kondo E, Mizutani A, Fujimura A.
- Journal Title
  
  Int. J. Clin. Pharmacol. Ther
  
  Volume: epub ahead of print Issue: 05 Pages: 409-415
- DOI
  10.5414/cp202788
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-26111005, KAKENHI-PROJECT-26290045, KAKENHI-PROJECT-16K15245
[Journal Article] Antitumor activity of the MEK inhibitor trametinib on intestinal polyp formation in ApcΔ716 mice involves stromal COX-2.2015
- Author(s)
  Fujishita T, Kajino-Sakamoto R, Kojima Y, Taketo MM, Aoki M.
- Journal Title
  
  Cancer Science
  
  Volume: 5（予定） Issue: 6 Pages: 692-699
- DOI
  10.1111/cas.12670
- NAID
  120005767023
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26830090, KAKENHI-PLANNED-26111005, KAKENHI-PROJECT-25253022, KAKENHI-PROJECT-26290045
[Presentation] がん悪液質の代謝学的特徴としての肝臓ビタミンB関連酵素群の減少2024
- Author(s)
  小島康
- Organizer
  第11回日本サルコペニア・悪液質・消耗性疾患研究会
- Invited
- Data Source
  KAKENHI-PROJECT-21K07140
[Presentation] がん悪液質における全身性代謝異常の解析2023
- Author(s)
  青木正博　曽我朋義　小島康
- Organizer
  がんと代謝研究会
- Data Source
  KAKENHI-PROJECT-21K07140
[Presentation] がん悪液質における肝臓代謝変化の特徴2023
- Author(s)
  小島康　三城恵美　武藤誠　曽我朋義　青木正博
- Organizer
  日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K07140
[Presentation] The landscape of systemic metabolic alterations in cancer cachexia2023
- Author(s)
  Aoki, M., Soga T., Kojima, Y
- Organizer
  The 7th Cancer Cachexia Conference, Edingburgh, Scotland
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07140
[Presentation] Metabolomic and proteomic landscape of cancer cachexia2022
- Author(s)
  Kojima, Y., Mishiro E., Taketo, M.M., Soga T. & Aoki M.
- Organizer
  The 81th Annual Meeting of the Japanese Cancer Association, Yokohama, Sep. 2022
- Data Source
  KAKENHI-PROJECT-21K07140
[Presentation] The landscape of systemic metabolic alterations in cancer cachexia2022
- Author(s)
  Aoki, M., Soga T., Kojima, Y
- Organizer
  The 7th JCA-AACR Special Joint Conference. The Latest Advances in Pancreatic Cancer Research, Kyoto, Jul. 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07140
[Presentation] 大腸腫瘍組織における翻訳後修飾変化の解析2021
- Author(s)
  三城恵美、藤下晃章、小島康、梶野リエ、田中努、田近正洋、青木正博
- Organizer
  日本プロテオーム学会2021年大会
- Data Source
  KAKENHI-PROJECT-18H02686
[Presentation] デュアルオミクス解析で明らかとなったがん悪液質に伴う肝臓の代謝変化の概要2021
- Author(s)
  青木正博、三城恵美、曽我朋義、小島康
- Organizer
  第80回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02686
[Presentation] 腸管腫瘍形成におけるDio2（２型脱ヨード酵素）の生物学的役割2019
- Author(s)
  小島　康
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K07191
[Presentation] cis-Apc/Smad4 マウスのMEK 阻害薬抵抗性腸管腺がんにおけるInpp5f タンパクの発現低下2019
- Author(s)
  藤下晃章、三城恵美、小島　康、武藤　誠、青木正博
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18H02686
[Presentation] 腸管腫瘍形成におけるDio2(2 型脱ヨード酵素）の生物学的役割2019
- Author(s)
  小島　康、藤下晃章、梶野リエ、三城恵美、武藤　誠、青木正博
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18H02686
[Presentation] Apc変異マウスの腸管腫瘍形成におけるMyD88の役割の解析2018
- Author(s)
  青木正博、小島康、曽我朋義
- Organizer
  第22回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-18H02686
[Presentation] 大腸がん形成におけるDio2の役割2018
- Author(s)
  小島康
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18H02686
[Presentation] Role of Dio2 (deiodinase, Iodothyronine, Type II) in colon tumorigenesis.2018
- Author(s)
  Kojima, Y., Fujishita T., Mishiro E., Kajino R., Taketo, M.M. & Aoki M.
- Organizer
  The 77th Annual Meeting of the Japanese Cancer Association, Osaka
- Data Source
  KAKENHI-PROJECT-17K07191
[Presentation] がん悪液質マウスモデルにおける全身的代謝異常2017
- Author(s)
  青木正博、小島康、曽我朋義
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-26290045
[Presentation] エルロチニブとトラメチニブの併用投与はcis-Apc/Smad4マウスの腸管腺がん形成を抑制する2017
- Author(s)
  津田都子、藤下晃章、小島康、武藤誠、青木正博
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-26290045
[Presentation] 腸管腫瘍の薬剤抵抗性獲得におけるEGF受容体の役割2017
- Author(s)
  藤下晃章，津田都子、小島康、武藤誠、青木正博
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-26290045
[Presentation] 新規がん悪液質マウスモデルの表現型解析2017
- Author(s)
  小島康、曽我朋義、武藤誠、青木正博
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-26290045
[Presentation] がん悪液質の代謝異常2017
- Author(s)
  青木正博、小島康、曽我朋義
- Organizer
  第5回がんと代謝研究会
- Data Source
  KAKENHI-PROJECT-26290045
[Presentation] II型脱ヨード酵素の大腸がん進展における役割2016
- Author(s)
  小島康、今度ゆりこ、藤下晃章、梶野リエ、武藤誠、青木正博
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Data Source
  KAKENHI-PROJECT-26290045
[Presentation] がん微小環境は浸潤性腸がんのmTOR阻害薬抵抗性獲得に関与する2016
- Author(s)
  藤下晃章、梶野リエ、小島康、武藤誠、青木正博
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Data Source
  KAKENHI-PROJECT-26290045
[Presentation] MEK/ERK経路の阻害はCOX2およびCCL2の発言レベルを減少させ腸管ポリープ形成を抑制する2015
- Author(s)
  藤下晃章、梶野リエ、小島康、武藤誠、青木正博
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知県・名古屋市）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26290045
[Presentation] 腸管腫瘍形成におけるJNK-mTORC1経路活性化機序の解析2015
- Author(s)
  梶野リエ、藤下晃章、小島康、武藤誠、青木正博
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知県・名古屋市）
- Year and Date
  2015-10-10
- Data Source
  KAKENHI-PROJECT-26290045
[Presentation] II型脱ヨード酵素の大腸がん進展における役割の検討2015
- Author(s)
  小島康、藤下晃章、武藤誠、青木正博
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知県・名古屋市）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26290045
[Presentation] 腸管腫瘍形成における甲状腺ホルモンの役割2015
- Author(s)
  小島康、オリム・フローレンス、藤下晃章、武藤誠、青木正博
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド（兵庫県・神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26290045
[Presentation] Apc+/Δ716マウスの腸管腫瘍におけるJNK-mTORC1経路活性化機序の解析2014
- Author(s)
  梶野　リエ、藤下晃章、小島　康、武藤　誠、青木　正博
- Organizer
  第37会日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(横浜市)
- Year and Date
  2014-11-25
- Data Source
  KAKENHI-PROJECT-26290045
[Presentation] 腸管腫瘍形成における JNK-mTORC1 経路活性化機序の解析2014
- Author(s)
  梶野　リエ、藤下晃章、小島　康、武藤　誠、青木　正博
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(横浜市)
- Year and Date
  2014-09-27
- Data Source
  KAKENHI-PROJECT-26290045
[Presentation] 日本人胃がん患者の体組成変化2013
- Author(s)
  小島康、松尾恵太郎、伊藤秀美、細野覚代、田中英夫、青木正博
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2013-10-05
- Data Source
  KAKENHI-PROJECT-24650627

1. AOKI MASAHIRO (60362464)

# of Collaborated Projects: 5 results

# of Collaborated Products: 22 results
2. 三城恵美 (00455544)

# of Collaborated Projects: 5 results

# of Collaborated Products: 7 results
3. 梶野リエ (20633184)

# of Collaborated Projects: 4 results

# of Collaborated Products: 9 results
4. 藤下晃章 (50511870)

# of Collaborated Projects: 4 results

# of Collaborated Products: 19 results
5. SAKUMA Keiichiro (90402891)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. TAKEDA Junji (50163407)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. ORIM FLORENCE (90750810)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. TABATA Sho

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. SAKAMOTO Takeharu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. DOI Hiroshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. TACHIBANA Izumi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 曽我朋義

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KOJIMA Yasushi 小島 康

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Molecular mechanisms maintaining the undifferntiated state of colorectal cancer stem cells

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がん悪液質の病態生理解明Principal Investigator

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Molecular mechanisms that maintain stemness in metastatic colorectal cancer

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Elucidating the pathophysiology of cancer cachexiaPrincipal Investigator

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Molecular mechanisms and preventive/therapeutic targets of colon cancer metastasis

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Roles of Dio2 (deiodinase, iodothyronine, type II) in colorectal tumorigenesisPrincipal Investigator

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Generation of a genetically engineered mouse model that reproducibly develops tumors in the large intestinePrincipal Investigator

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Elucidating the mechanisms of colorectal cancer metastasis using mouse models

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Development of in vivo screening systems for cancer metastasis suppressors

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Roles of nuclear pore complex and lamina in intestinal tumor formationPrincipal Investigator

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[Journal Article] がん悪液質に伴う代謝臓器変容のマルチオミクス解析2024

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[Journal Article] Decreased liver B vitamin-related enzymes as a metabolic hallmark of cancer cachexia2023

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[Journal Article] L-2hydroxyglutaric acid rewires amino acid metabolism in colorectal cancer via the mTOR-ATF4 axis2023

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KOJIMA Yasushi 小島康