Hiroshi Ohkawara 大河原浩

… Alternative Names

大河原浩オオカワラヒロシ

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Researcher Number	10381360
Other IDs
Affiliation (Current)	2025: 福島県立医科大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2019 – 2023: 福島県立医科大学, 医学部, 准教授 2018: 福島県立医科大学, 医学部, 講師 2017: 福島県立医科大学, 医学部, 准教授
Review Section/Research Field	Principal Investigator Basic Section 54010:Hematology and medical oncology-related / Hematology Except Principal Investigator Basic Section 54010:Hematology and medical oncology-related
Keywords	Principal Investigator 造血幹細胞移植 / VOD/SOS / 血栓性微小血管障害症 / 移植片対宿主病 / TA-TMA / GVHD / 内皮障害 / Mer / 同種造血幹細胞移植 / Gas6 … More Except Principal Investigator … More 同種造血幹細胞移植 / HSCT / Mer / Gas6 / 生着不全 / TAM受容体 / 急性移植片対宿主病 / 血栓性微小血管障害症 / TA-TMA / TMA / GVHD / 移植後TMA / 造血幹細胞移植 / HMGA2 / ヒストン修飾 / ドライバー変異 / カルレチクリン / ポリコーム抑制複合体 / CALR変異 / CALR / 髄外造血 / 血管病変 / 病態進展 / 骨髄増殖性腫瘍 Less

造血細胞移植後VOD/SOSに対する新たな治療戦略Principal Investigator
- Principal Investigator
  
  大河原浩
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Fukushima Medical University
Therapeutic Strategies and Biomarkers for Graft Failure in Allogenic Hematopoietic Cell Transplantation
- Principal Investigator
  
  Ogawa Kazuei
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Fukushima Medical University
Mutual role of a driver mutation and abnormality of histone modification in progression of myeloproliferative neoplasms
- Principal Investigator
  
  Ikeda Kazuhiko
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Fukushima Medical University
A critical role of Gas6-TAM signaling pathway in the pathology of HSCT-associated TMA
- Principal Investigator
  
  Ogawa Kazuei
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Fukushima Medical University
Critical roles of Gas6 in the pathology of GVHDPrincipal Investigator
- Principal Investigator
  
  Hiroshi Ohkawara
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Fukushima Medical University

All 2020 2019 2018 2017

All Journal Article Presentation

[Journal Article] Optimal timing of apheresis for the efficient mobilization of peripheral blood progenitor cells recruited by high-dose granulocyte colony-stimulating factor in healthy donors2020
- Author(s)
  Kimura Satoshi、Ohkawara Hiroshi、Minakawa Keiji、Fukatsu Masahiko、Mori Hirotaka、Takahashi Hiroshi、Harada-Shirado Kayo、Ohara Yoshihiro、Takahashi Nobuhisa、Mochizuki Kazuhiro、Sano Hideki、Nollet Kenenth E、Ogawa Kazuei、Ohto Hitoshi、Kikuta Atsushi、Ikeda Kazuhiko、Ikezoe Takayuki
- Journal Title
  
  Transfusion and Apheresis Science
  
  Volume: - Issue: 3 Pages: 102737-102737
- DOI
  10.1016/j.transci.2020.102737
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08365, KAKENHI-PROJECT-18H02844
[Journal Article] The link between interleukin-1β and acute myocardial infarction in chronic myeloid leukemia patients treated with nilotinib: crosssectional study2020
- Author(s)
  Hirotaka Mori, Masumi Sukegawa, Masahiko Fukatsu, Takahiro Sano, Hiroshi Takahashi, Kayo Harada, Satoshi Kimura, Hiroshi Ohkawara, Kenichi Nakamura, Masayuki Mita, Tomiyoshi Saito, Yoichi Hamazaki, Masatsugu Ohta, Takayuki Ikezoe
- Journal Title
  
  Annals of Hematology
  
  Volume: 99 (2) Pages: 359-361
- Data Source
  KAKENHI-PROJECT-17K09959
[Journal Article] Optimal timing of apheresis for the efficient mobilization of peripheral blood progenitor cells recruited by high-dose granulocyte colony-stimulating factor in healthy donors2020
- Author(s)
  Satoshi Kimura, Hiroshi Ohkawara, Keiji Minakawa, Masahiko Fukatsu, Hirotaka Mori, Hiroshi Takahashi, Kayo Harada-Shirado, Yoshihiko Ohara, Nobuhisa Takahashi, Kazuhiko Mochizuki, Hideki Sano, Kenenth E Nollet, Kazuei Ogawa, Hitoshi Ohto, Atsushi Kikuta, Kazuhiko Ikeda, Takayuki Ikezoe
- Journal Title
  
  Transfusion and Apheresis Science
  
  Volume: 59 (3) Pages: 102737-102737
- Data Source
  KAKENHI-PROJECT-17K09959
[Journal Article] Circulating intranuclear proteins may play a role in development of disseminated intravascular coagulation in individuals with acute leukemia2020
- Author(s)
  Kayo Harada-Shirado, Xintao Wang, Hirotaka Mori, Masahiko Fukatsu, Hiroshi Takahashi, Akiko Shichishima-Nakamura, Satoshi Kimura, Hiroshi Ohkawara, Shingo Yamada, Takashi Ito, Takayuki Ikezoe
- Journal Title
  
  International Journal of Hematology
  
  Volume: 111 (3) Pages: 378-387
- Data Source
  KAKENHI-PROJECT-17K09959
[Journal Article] A critical role of the Gas6-Mer axis in endothelial dysfunction contributing to TA-TMA associated with GVHD2019
- Author(s)
  Miki Furukawa, Xintao Wang, Hiroshi Ohkawara, Masahiko Fukatsu, Lobna Alkebsi, Hiroshi Takahashi, Kayo Harada-Shirado, Akiko Shichishima-Nakamura, Satoshi Kimura, Kazuei Ogawa, Takayuki Ikezoe
- Journal Title
  
  Blood Advances
  
  Volume: 3（14） Pages: 2128-2143
- Data Source
  KAKENHI-PROJECT-18K08366
[Journal Article] A critical role of the Gas6-Mer axis in endothelial dysfunction contributing to TA-TMA associated with GVHD2019
- Author(s)
  Miki Furukawa, Xintao Wang, Hiroshi Ohkawara, Masahiko Fukatsu, Lobna Alkebsi, Hiroshi Takahashi, Kayo Harada-Shirado, Akiko Shichishima-Nakamura, Satoshi Kimura, Kazuei Ogawa, Takayuki Ikezoe
- Journal Title
  
  Blood advances
  
  Volume: 3 (14) Pages: 2128-2143
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09959
[Journal Article] Lenalidomide as a Beneficial Treatment Option for Renal Impairment Caused by Light Chain Deposition Disease2018
- Author(s)
  Kimura Satoshi、Ohkawara Hiroshi、Ogawa Kazuei、Tanaka Mizuko、Sano Takahiro、Harada-Shirado Kayo、Takahashi Hiroshi、Ueda Koki、Shichishima-Nakamura Akiko、Matsumoto Hayato、Ikeda Kazuhiko、Kazama Junichiro James、Hashimoto Yuko、Ikezoe Takayuki
- Journal Title
  
  Intern. Med.
  
  Volume: 57 Issue: 24 Pages: 3651-3657
- DOI
  10.2169/internalmedicine.1018-18
- NAID
  130007531184
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2018-12-15
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08365
[Presentation] HIV 感染に合併した赤芽球癆の 1 例2020
- Author(s)
  木村哲, 永田兼司, 柳沼真維, 深津真彦, 原田佳代, 遠藤麻美子, 森博隆, 高橋裕志, 大河原浩, 小川一英, 橋本優子, 池添隆之
- Organizer
  第 82 回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-17K09959
[Presentation] IgG4 関連疾患の治療中に発症したびまん性大細胞型 B 細胞リンパ腫の 1 例2020
- Author(s)
  栁沼真維, 深津真彦, 原田佳代, 木村哲, 遠藤麻美子, 森博隆, 高橋裕志, 大河原浩, 橋本優子, 池添隆之
- Organizer
  第 221 回日本内科学会東北地方会
- Data Source
  KAKENHI-PROJECT-17K09959
[Presentation] 急性白血病の DIC 診断における核内蛋白の有用性について2020
- Author(s)
  原田佳代, 森博隆, 深津真彦, 佐野隆浩, 高橋裕志, 木村哲, 大河原浩, 山田晋吾, 池添隆之
- Organizer
  第 82 回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-17K09959
[Presentation] 血液腫瘍に合併する DIC の診断における核内蛋白の有用性について2020
- Author(s)
  原田佳代, 森博隆, 深津真彦, 佐野隆浩, 高橋裕志, 木村哲, 大河原浩, 山田晋吾, 池添隆之
- Organizer
  第 21 回日本検査血液学会学術集会
- Data Source
  KAKENHI-PROJECT-17K09959
[Presentation] 発症後 4 日で突然の心停止に至った血栓性血小板減少性紫斑病の 1 剖検例2020
- Author(s)
  高田満喜, 関根黎, 深津真彦, 森博隆, 原田佳代, 木村哲, 大河原浩, 小川一英, 池添隆之
- Organizer
  第 219 回日本内科学会東北地方会
- Data Source
  KAKENHI-PROJECT-17K09959
[Presentation] 造血器腫瘍に合併する DIC への核内蛋白の関与2020
- Author(s)
  原田佳代, 王新涛, 森博隆, 深津真彦, 高橋裕志, 七島晶子, 木村哲, 大河原浩, 山田晋吾, 伊藤隆史, 池添隆之
- Organizer
  第 14 回日本血栓止血学会学術標準化委員会シンポジウム
- Data Source
  KAKENHI-PROJECT-17K09959
[Presentation] 難治性結節性リンパ球優位型ホジキンリンパ腫に対して rituximab 併用化学療法が奏功した一例2020
- Author(s)
  矢澤里穂, 佐野隆浩, 高橋裕志, 大河原浩, 橋本優子, 池添隆之
- Organizer
  第 129 回日本血液学会東北地方会
- Data Source
  KAKENHI-PROJECT-17K09959
[Presentation] 当院におけるポナチニブの使用経験2020
- Author(s)
  大河原浩
- Organizer
  Ph+白血病学術講演会
- Data Source
  KAKENHI-PROJECT-17K09959
[Presentation] ARDSの新規治療ターゲット：Gas6-Merシグナル2019
- Author(s)
  第81回　日本血液学会学術集会 (2019.10.11-10.13, 東京) 古川未希, 王新涛, 大河原浩, 深津真彦, Alkebsi Lobna, 小川一英, 池添隆之.
- Organizer
  第81回　日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08366
[Presentation] A Critical Role of Growth Arrest-Specific Gene 6-Mer Axis in the Pathogenesis of Endothelial Damage Contributing to Thrombotic Microangiopathy Associated with Graft-Versus-Host Disease after Allogeneic Hematopoietic Stem Cell Transplantation2018
- Author(s)
  古川未希　大河原浩
- Organizer
  2018年12月米国血液学会学術集会(サンディエゴ)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09959
[Presentation] GVHD及びTMAの病態におけるGas6-TAM受容体シグナルの関与2018
- Author(s)
  古川未希　大河原浩　小川一英　池添隆之
- Organizer
  2018年10月日本血液学会総会（大阪）
- Data Source
  KAKENHI-PROJECT-18K08366
[Presentation] A Critical Role of Growth Arrest-Specific Gene 6-Mer Axis in the Pathogenesis of Endothelial Damage Contributing to Thrombotic Microangiopathy Associated with Graft-Versus-Host Disease after Allogeneic Hematopoietic Stem Cell Transplantation2018
- Author(s)
  古川未希　大河原浩　小川一英　池添隆之
- Organizer
  2018年12月米国血液学会学術集会(サンディエゴ)
- Data Source
  KAKENHI-PROJECT-18K08366
[Presentation] GVHD及びTMAの病態におけるGas6-TAM受容体シグナルの関与2018
- Author(s)
  古川未希　大河原浩
- Organizer
  2018年10月日本血液学会総会（大阪）
- Data Source
  KAKENHI-PROJECT-17K09959
[Presentation] A critical role of growth arrest-specific gene 6 in the pathogenesis of HSCT-associated thrombotic microangiopathy.2017
- Author(s)
  Sho Takeyasu, Hiroshi Ohkawara, Koichiro Fukuchi, Wang Xiangmin, Koki Ueda, Kazuhiko Ikeda, Kazuei Ogawa,Takayuki Ikezoe.
- Organizer
  第79回日本血液学会学術集会 (2017.10.20東京)　優秀ポスター賞受賞
- Data Source
  KAKENHI-PROJECT-17K09959

1. 池添隆之 (80294833)

# of Collaborated Projects: 4 results

# of Collaborated Products: 16 results
2. Ogawa Kazuei (40423800)

# of Collaborated Projects: 3 results

# of Collaborated Products: 9 results
3. Ikeda Kazuhiko (90381392)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
4. 深津真彦 (30827829)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 橋本優子 (60305357)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Hiroshi Ohkawara 大河原 浩

大河原 浩 オオカワラ ヒロシ

Research Projects

Research Products

Co-Researchers

造血細胞移植後VOD/SOSに対する新たな治療戦略Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Therapeutic Strategies and Biomarkers for Graft Failure in Allogenic Hematopoietic Cell Transplantation

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mutual role of a driver mutation and abnormality of histone modification in progression of myeloproliferative neoplasms

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

A critical role of Gas6-TAM signaling pathway in the pathology of HSCT-associated TMA

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Critical roles of Gas6 in the pathology of GVHDPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Optimal timing of apheresis for the efficient mobilization of peripheral blood progenitor cells recruited by high-dose granulocyte colony-stimulating factor in healthy donors2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The link between interleukin-1β and acute myocardial infarction in chronic myeloid leukemia patients treated with nilotinib: crosssectional study2020

Author(s)

Journal Title

Data Source

[Journal Article] Optimal timing of apheresis for the efficient mobilization of peripheral blood progenitor cells recruited by high-dose granulocyte colony-stimulating factor in healthy donors2020

Author(s)

Journal Title

Data Source

[Journal Article] Circulating intranuclear proteins may play a role in development of disseminated intravascular coagulation in individuals with acute leukemia2020

Author(s)

Journal Title

Data Source

[Journal Article] A critical role of the Gas6-Mer axis in endothelial dysfunction contributing to TA-TMA associated with GVHD2019

Author(s)

Journal Title

Data Source

[Journal Article] A critical role of the Gas6-Mer axis in endothelial dysfunction contributing to TA-TMA associated with GVHD2019

Author(s)

Journal Title

Data Source

[Journal Article] Lenalidomide as a Beneficial Treatment Option for Renal Impairment Caused by Light Chain Deposition Disease2018

Author(s)

Journal Title

DOI

NAID

ISSN

Year and Date

Language

Data Source

[Presentation] HIV 感染に合併した赤芽球癆の 1 例2020

Author(s)

Organizer

Data Source

[Presentation] IgG4 関連疾患の治療中に発症したびまん性大細胞型 B 細胞リンパ腫の 1 例2020

Author(s)

Organizer

Data Source

[Presentation] 急性白血病の DIC 診断における核内蛋白の有用性について2020

Author(s)

Organizer

Hiroshi Ohkawara 大河原浩

大河原浩オオカワラヒロシ

[Presentation] 難治性結節性リンパ球優位型ホジキンリンパ腫に対して rituximab 併用化学療法が奏功した一例2020