Imai Takao 今井貴雄

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IMAI TAKAO 今井貴雄

IMAI Takao 今井貴雄

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Researcher Number	10383712
Other IDs
Affiliation (based on the past Project Information) *help	2018: 慶應義塾大学, 医学部(信濃町), 特任助教 2016: 慶應義塾大学, 医学部(信濃町), 特任准教授 2012 – 2015: 慶應義塾大学, 医学部, 助教 2014: 慶應義塾大学, 医学部生理学教室, 助教 2007 – 2010: Keio University, 医学部, 助教 2005 – 2006: 慶應義塾大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Neurochemistry/Neuropharmacology / Neurochemistry/Neuropharmacology / 医学物理学・放射線技術学 Except Principal Investigator Neurochemistry/Neuropharmacology / Ophthalmology
Keywords	Principal Investigator 神経幹細胞 / RNA結合蛋白質 / Musashi / 神経系 / RNA / ゲノム編集 / let-7 / miRNA / 幹細胞 / 翻訳制御 … More / 翻訳調節 / 翻訳 / iPS細胞 / Oct4 / 多能性幹細胞 / 蛍光蛋白質 / DNA傷害 / レポーター遺伝子 / 放射線 / p53 / 神経細胞 / 転写後調節 / 翻訳抑制 / 蛋白質 / 神経生物学 / 細胞 / 分子 / 3'非翻訳領域 / 翻訳開始因子 / タンパク質 / eIF4G / PABP … More Except Principal Investigator 分化 / 再生医学 / 幹細胞 / Dcx / Dcc / Musashi / 神経分化 / 転写後制御 / 翻訳制御 / 未分化維持 / 神経回路 / 神経発生 / RNA結合タンパク質 / Musashi1 / シグナル伝達 / サイトカイン / 炎症 / 再生 / 発生 / 視機能 / 網膜 Less

Development of pluripotent gene expression indicator using CRISPR/Cas9 genome editing and the study regarding tumorigenicity of human pluripotent stem cell-derived neural stem cells.Principal Investigator
- Principal Investigator
  
  Imai Takao
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Keio University
Analysis for a neural differentiation regulatory factor, Musashi1
- Principal Investigator
  
  HORISAWA Kenichi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Kyushu University
  Keio University
Establishment of the reporter stem cell lines capable of evaluating the cell influence by radiation.Principal Investigator
- Principal Investigator
  
  IMAI TAKAO
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  医学物理学・放射線技術学
- Research Institution
  Keio University
Elucidation of the molecular mechanism for inhibition of let-7 miRNA function by RNA-binding protein Musashi1Principal Investigator
- Principal Investigator
  
  IMAI Takao
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Keio University
The mechanism of photoreceptor cell differentiation to utilize in retinal regenerative therapy
- Principal Investigator
  
  OZAWA Yoko
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Keio University
Identification of target RNAs for neural RNA-binding protein Musashi1Principal Investigator
- Principal Investigator
  
  IMAI Takao
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Keio University
RNA結合蛋白質Musashiが介する神経幹細胞における翻訳調節の分子機構解明Principal Investigator
- Principal Investigator
  
  今井貴雄
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Keio University

All 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2005 Other

All Journal Article Presentation

[Journal Article] Rfx Transcription Factors Control Musashi1 Transcription in Mouse Neural Stem/Progenitor Cells.2014
- Author(s)
  Kawase S, Kuwako K, Imai T, Renault-Mihara F, Yaguchi K, Itohara S, Okano H.
- Journal Title
  
  Stem Cells Dev.
  
  Volume: 23 Issue: 18 Pages: 2250-2261
- DOI
  10.1089/scd.2014.0219
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24500447, KAKENHI-PROJECT-25430073
[Journal Article] Musashi-1 post-transcriptionally enhances phosphotyrosine-binding domain- containing m-Numb protein expression in regenerating gastric mucosa.2013
- Author(s)
  Tetsufumi Takahashi
- Journal Title
  
  PLoS One
  
  Volume: 8 Issue: 1 Pages: 1-13
- DOI
  10.1371/journal.pone.0053540
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300169, KAKENHI-PROJECT-22600011, KAKENHI-PROJECT-24249046, KAKENHI-PROJECT-24500447, KAKENHI-PROJECT-24601016, KAKENHI-PROJECT-24659103, KAKENHI-PROJECT-25293178
[Journal Article] The long non-coding RNA nuclear-enriched abundant transcript 1_2 induces paraspeckle formation in the motor neuron during the early phase of amyotrophic lateral sclerosis2013
- Author(s)
  Nishimoto, Y., Nakagawa, S., Hirose, T., Okano, H. J., Takao, M., Shibata, S., Suyama, S., Kuwako, K., Imai, T., Murayama, S., Suzuki, N., and Okano, H
- Journal Title
  
  Mol. Brain
  
  Volume: 6 Issue: 1 Pages: 31-31
- DOI
  10.1186/1756-6606-6-31
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21228003, KAKENHI-PUBLICLY-24111543, KAKENHI-PROJECT-24300122, KAKENHI-PROJECT-24500447, KAKENHI-PROJECT-24601016, KAKENHI-PROJECT-25430073
[Journal Article] Cellular toxicity induced by the 26-kDa fragment and amyotrophic lateral sclerosis-associated mutant forms of TAR DNA-binding protein 43 in human embryonic stem cell-derived motor neurons.2013
- Author(s)
  Nishimoto Y., Okano HJ, Imai T., Poole AJ., Suzuki N., Keirstead HS and Okano H.
- Journal Title
  
  Neurology and Clinical Neuroscience
  
  Volume: 1 Issue: 1 Pages: 24-31
- DOI
  10.1002/ncn3.2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24601016
[Journal Article] RNA-Binding Protein Musashi1 Modulates Glioma Cell Growth through the Post-Transcriptional Regulation of Notch and PI(3) Kinase/Akt Signaling Pathways2012
- Author(s)
  Muto J, Imai T, Ogawa D, Nishimoto Y, Okada Y, Mabuchi Y, Kawase T, Iwanami A, Mischel PS, Saya H, Yoshida K, Matsuzaki Y, Okano H
- Journal Title
  
  PLoS One
  
  Volume: 7(3) Issue: 3 Pages: e33431-e33431
- DOI
  10.1371/journal.pone.0033431
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390062, KAKENHI-PUBLICLY-23110516, KAKENHI-PROJECT-23650194, KAKENHI-PROJECT-23689017, KAKENHI-PROJECT-23791002, KAKENHI-PROJECT-23791446, KAKENHI-PROJECT-24500447
[Journal Article] RNA結合タンパク質による遺伝子制御と神経発生・神経機能2012
- Author(s)
  今井貴雄、岡野栄之
- Journal Title
  
  細胞工学6月号特集「神経細胞特異的な翻訳制御：鍵を握るRNA結合タンパク質/mRNA輸送/non-coding RNA」編者：武井延之
  
  Volume: 31 Pages: 668-674
- Data Source
  KAKENHI-PROJECT-24601016
[Journal Article] RNA結合タンパク質による遺伝子制御と神経発生・神経機能2012
- Author(s)
  今井貴雄、岡野栄之
- Journal Title
  
  細胞工学
  
  Volume: 31 Pages: 668-674
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24500447
[Journal Article] Identification of a Novel Intronic Enhancer Responsible for the Transcriptional Regulation of Musashil in Neural Stem/Progenitor Cells.2011
- Author(s)
  Kawase S, Imai T, Miyauchi-Hara C, Yaguchi K, Nishimoto Y, Fukami SI, Matsuzaki Y, Miyawaki A, Itohara S, Okano H
- Journal Title
  
  Molecular Brain 4(1)[Epub ahead of print]
  
  Pages: 14-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21700413
[Journal Article] Identification of a Novel Intronic Enhancer Responsible for the Transcriptional Regulation of Musashil in Neural Stem/Progenitor Cells.2011
- Author(s)
  Kawase S, Imai T, Miyauchi-Hara C, Yaguchi K, Nishimoto Y, Fukami SI, Matsuzaki Y, Miyawaki A, Itohara S, Okano H
- Journal Title
  
  Molecular Brain
  
  Volume: 4(Epub ahead of print)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21700413
[Journal Article] Musashi 1 cooperates in abnormal cell LINeage protein 28 (Lin28)-mediated Let-7 family microRNA biogenesis in early neural differentiation.2011
- Author(s)
  Kawahara H, Okada Y, Imai T, Iwanami A, Mischel PS, Okano H.
- Journal Title
  
  J Biol Chem. 286
  
  Pages: 16121-16130
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21700413
[Journal Article] Musashi 1 cooperates in abnormal cell LINeage protein 28 (Lin28)-mediated Let-7 family microRNA biogenesis in early neural differentiation.2011
- Author(s)
  Kawahara H, Okada Y, Imai T, Iwanami A, Mischel PS, Okano H.
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 286(Epub ahead of print)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21700413
[Journal Article] Neural RNA-binding protein Musashil controls midline crossing of precerebellar neurons through posttranscriptional regulation of Robo3/Rig-1 expression.2010
- Author(s)
  Kuwako K, Kakumoto K, Imai T, Igarashi M, Hamakubo T, Sakakibara S, Tessier-Lavigne M, Okano HJ, Okano H.
- Journal Title
  
  Neuron. 12;67(3)
  
  Pages: 407-421
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21700413
[Journal Article] The Musashi family RNA-binding proteins in stem cells.2010
- Author(s)
  Horisawa K., Imai T, Okano H, Yanagawa H.
- Journal Title
  
  BioMol Concepts Vol.1
  
  Pages: 59-66
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21700413
[Journal Article] Musashil as a marker of reactive astrocytes after transient focal brain ischemia.2010
- Author(s)
  Oki K., Kaneko N., Kanki H., Imai T., Suzuki N., Sawamoto K., Okano H.
- Journal Title
  
  Neuroscience Research 66
  
  Pages: 390-395
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21700413
[Journal Article] The Musashi family RNA-binding proteins in stem cells.2010
- Author(s)
  Horisawa K., Imai T, Okano H, Yanagawa H
- Journal Title
  
  BioMol Concepts
  
  Volume: 1 Pages: 59-66
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21700413
[Journal Article] Neural RNA-binding protein Musashi1 controls midline crossing of precerebellar neurons through posttranscriptional regulation of Robo3/Rig-1 expression.2010
- Author(s)
  Kuwako K, Kakumoto K, Imai T, Igarashi M, Hamakubo T, Sakakibara S, Tessier-Lavigne M, Okano HJ, Okano H.
- Journal Title
  
  Neuron
  
  Volume: 12 Pages: 407-421
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21700413
[Journal Article] Musashil as a marker of reactive astrocytes after transient focal brain ischemia.2010
- Author(s)
  Oki K, Kaneko N, Kanki H, Imai T, Suzuki N, Sawamoto K, Okano H.
- Journal Title
  
  Neurosci Res. 66
  
  Pages: 305-309
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21700413
[Journal Article] 3'-Untranslated region of doublecortin mRNA is a binding target of the Musashil RNA-binding protein.2009
- Author(s)
  Horisawa K., Imai T., Okano H., Yanagawa H.
- Journal Title
  
  FEBS Letters 583
  
  Pages: 2429-2434
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21700413
[Journal Article] 3'-Untranslated region of doublecortin mRNA is a binding target of the Musashil RNA-binding protein.2009
- Author(s)
  Horisawa K, Imai T, Okano H, Yanagawa H.
- Journal Title
  
  FEBS Lett. 583(14)
  
  Pages: 2429-2434
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21700413
[Journal Article] Neural RNA-binding protein Musashil inhibits translation ini tiation by competing with eIF4G for PABP2008
- Author(s)
  Kawahara H, Imai T, Imataka H, Tsujimoto M, Matsumoto K. Okano H.
- Journal Title
  
  Journal of Cell Biology 181
  
  Pages: 639-653
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19700348
[Journal Article] Neural RNA-binding protein Musashil Inhibits Translation Initiation by Competing with eIF4G for PABP.2008
- Author(s)
  Kawahara H., Imai T., Imataka H., Tsi!jimoto M., Matsumoto K. and Okano H.
- Journal Title
  
  Journal of Cell Biofogy (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19700348
[Journal Article] Structural analysis of Musashi-RNA complex on the basis of long-range structural information2008
- Author(s)
  Ohyama T, Furukawa A, Mashima T, Sugiyama T, Ohgara S, Yamazaki T, Imai T, Okano H, Nagata T, Katahira M
- Journal Title
  
  Nucleic Acids Symp Ser (Oxf) 52
  
  Pages: 193-194
- Data Source
  KAKENHI-PROJECT-19592038
[Journal Article] Neural RNA-binding protein Musashi1 inhibits translation initiation by competing with eIF4G for PABP.2008
- Author(s)
  Kawahara H, Imai T, Imataka H, Tsujimoto M, Matsumoto K, Okano H.
- Journal Title
  
  Journal of Cell Biology 181
  
  Pages: 639-6532
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19700348
[Journal Article] Neural RNA-binding protein Musashil inhibits translation initiation by competing with eIF4G for PABP2008
- Author(s)
  Kawahara H, Imai T, Imataka H, Tsujimoto M, Matsumoto K, Okano H
- Journal Title
  
  J Cell Biol 181(4)
  
  Pages: 639-653
- Data Source
  KAKENHI-PROJECT-19592038
[Journal Article] Interactions with RNA/DNA of proteins involved in the regulation of transcription, translation and telomere elongation2007
- Author(s)
  Ohyama T, Furukawa A, Miyoshi T, Takada Y, Ohgara S, Hiratsuka K, Imai T, Okano H, Nakagama H, Nagata T, Katahira M
- Journal Title
  
  Nucleic Acids Symp Ser (Oxf) 51
  
  Pages: 77-78
- Data Source
  KAKENHI-PROJECT-19592038
[Journal Article] Functions of neural RNA-binding proteins Musashi and Hu in stem cells and neuronal differentiation.2007
- Author(s)
  Kawahara H., Yano M., Imai T., Akamatsu W., Okano HJ., Okano H.
- Journal Title
  
  RNA Binding Proteins in Development and Disease. (Denman RB. ed.)(Research SignPost) (印刷中)
- Data Source
  KAKENHI-PROJECT-17700354
[Journal Article] Hzf protein regulates dendritic localization and BDNF-induced translation of type 1 inositol 1,4,5-trisphosphate receptor mRNA2005
- Author(s)
  Iijima T., Imai T., Kimura Y., Bernstein A., Okano HJ., Yuzaki M., Okano H.
- Journal Title
  
  Proceedings of the National Academy of Sciences of the USA 102
  
  Pages: 17190-17195
- Data Source
  KAKENHI-PROJECT-17700354
[Journal Article] Function of RNA binding protein Musashi-1 in stem cells.2005
- Author(s)
  Okano H., Kawahara H., Toriya M., Nakao K., Shibata S., Imai T.
- Journal Title
  
  Experimental Cell Research 306
  
  Pages: 349-356
- Data Source
  KAKENHI-PROJECT-17700354
[Presentation] 眼咽頭筋ジストロフィー原因遺伝子PABPN1の持続性発現による疾患モデル作成および機能解析2016
- Author(s)
  今井貴雄、松本恵、熊谷恵、井上浩義、岡野栄之、池田正明、中尾啓子
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15K06779
[Presentation] Functional and pathological analysis of PABPN1, a responsible gene for oculopharyngeal muscular dystrophy (OPMD), that is introduced into mouse skeletal muscles by in vivo electroporation.2016
- Author(s)
  Keiko Nakao，Megumi Matsumoto，Megumi Kumagai，Masaaki Ikeda，Takao Imai
- Organizer
  第39回日本神経科学大会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-07-20
- Data Source
  KAKENHI-PROJECT-15K06779
[Presentation] in vivo 電気穿孔法を用いて作成した眼咽頭筋ジストロフィ疾患モデルにおける原因遺伝子PABPN1の機能解析2015
- Author(s)
  中尾啓子、松本恵、熊谷恵、溝井令一、荒木信夫、池田正明、今井貴雄
- Organizer
  第３８回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド（神戸国際展示場）（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K06779
[Presentation] Musashi1 Post-Transcriptionally Regulates The Gene Expression In Neural Stem/Progenitor Cells And Glioma.2012
- Author(s)
  Imai T., Muto J., Kawase S., Shibata S., Okano H.
- Organizer
  The 4th Biennial Symposium on Brain and Mind Research in the Asia-Pacific (BMAP 2012)/The FIRST Program ‘Strategic Exploitation of Neuro-Genetics for Emergence of the Mind’ Symposium (FIRST 2012)
- Place of Presentation
  North Hall, Mita Campus, Keio University, Tokyo, Japan
- Data Source
  KAKENHI-PROJECT-24601016
[Presentation] ヒト悪性脳腫瘍癌幹細胞におけるMusashiの発現と抗腫瘍効果のメカニズム2011
- Author(s)
  武藤淳、今井貴雄、馬渕洋、松崎由未、吉田一成、岡野栄之
- Organizer
  第10回日本再生医療学会総会、O-19-6、会期3/1-2
- Place of Presentation
  京王プラザホテル・東京
- Year and Date
  2011-03-02
- Data Source
  KAKENHI-PROJECT-21700413
[Presentation] ヒト悪性脳腫瘍癌幹細胞におけるMusashiの発現と抗腫瘍効果のメカニズム2011
- Author(s)
  武藤淳、今井貴雄、馬渕洋、松崎由未、吉田一成、岡野栄之
- Organizer
  第10回日本再生医療学会総会
- Place of Presentation
  京王プラザホテル・東京
- Year and Date
  2011-03-02
- Data Source
  KAKENHI-PROJECT-21700413
[Presentation] 神経幹細胞におけるmusashi1遺伝子の転写制御解析2010
- Author(s)
  河瀬聡、今井貴雄、原央子、矢口邦夫、糸原重美、岡野栄之
- Organizer
  第33回日本神経科学会・第50回日本神経化学会・第20回神経回路学会合同年会
- Place of Presentation
  神戸国際会議場・神戸
- Year and Date
  2010-09-02
- Data Source
  KAKENHI-PROJECT-21700413
[Presentation] Ribonomics解析によるMusashiを介したmRNA regulonの同定2010
- Author(s)
  今井貴雄、河原裕憲、河瀬聡、岩成宏子、望月康弘、児玉龍彦、浜窪隆雄、岡野栄之
- Organizer
  第12回日本RNA学会年会、P-120、会期7/27-29
- Place of Presentation
  一橋記念講堂・東京
- Year and Date
  2010-07-28
- Data Source
  KAKENHI-PROJECT-21700413
[Presentation] Ribonomics解析によるMusashiを介したmRNA regulonの同定2010
- Author(s)
  今井貴雄、河原裕憲、河瀬聡、岩成宏子、望月康弘、児玉龍彦、浜窪隆雄、岡野栄之
- Organizer
  第12回日本RNA学会年会
- Place of Presentation
  一橋記念講堂・東京
- Year and Date
  2010-07-28
- Data Source
  KAKENHI-PROJECT-21700413
[Presentation] 分化制御の鍵をにぎる翻訳抑制複合体のNMR構造機能解析2010
- Author(s)
  大山貴子、永田崇、田中志穂、飯倉裕之、河原裕憲、今井貴雄、岡野栄之、山崎俊夫、片平正人
- Organizer
  第12回日本RNA学会年会、P-119、会期7/27-29
- Place of Presentation
  一橋記念講堂・東京
- Year and Date
  2010-07-27
- Data Source
  KAKENHI-PROJECT-21700413
[Presentation] 分化制御の鍵をにぎる翻訳抑制複合体のNMR構造機能解析2010
- Author(s)
  大山貴子、永田崇、田中志穂、飯倉裕之、河原裕憲、今井貴雄、岡野栄之、山崎俊夫、片平正人
- Organizer
  第12回日本RNA学会年会
- Place of Presentation
  一橋記念講堂・東京
- Year and Date
  2010-07-27
- Data Source
  KAKENHI-PROJECT-21700413
[Presentation] 神経幹細胞におけるmusashil遺伝子の転写制御解析2010
- Author(s)
  河瀬聡、今井貴雄、原央子、矢口邦夫、糸原重美、岡野栄之
- Organizer
  第33回日本神経科学会・第50回日本神経化学会・第20回神経回路学会合同年会、P1-d18、会期9/2-4
- Place of Presentation
  神戸国際会議場・神戸
- Year and Date
  2010-09-02
- Data Source
  KAKENHI-PROJECT-21700413
[Presentation] RNA結合蛋白質Msi1と新規標的mRNAの相互作用解析2010
- Author(s)
  堀澤健一、松尾薫、今井貴雄、岡野栄之、柳川弘志
- Organizer
  第12回日本RNA学会年会
- Place of Presentation
  一橋記念講堂・東京
- Year and Date
  2010-07-28
- Data Source
  KAKENHI-PROJECT-21700413
[Presentation] Analysis of Musashil function in human glioma stem cells and development of gene therapy for tumor growth suppression.2009
- Author(s)
  Jun Muto, Takao Imai, Yumi Matsuzaki, Takeshi Kawase, Hideyuki Okano
- Organizer
  第7回幹細胞シンポジウム
- Place of Presentation
  泉ガーデンギャラリー,東京
- Year and Date
  2009-05-15
- Data Source
  KAKENHI-PROJECT-21700413
[Presentation] RNA結合蛋白質Musashilのlet-7 miRNA機能発現に対する制御(RNA-binding protein Musashil regulates the function of let-7 miRNAs.)2009
- Author(s)
  今井貴雄, 河原裕憲, 河瀬聡, 岡野栄之
- Organizer
  第32回日本分子生物学会年会(MBSJ2009)1P-0286
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2009-12-09
- Data Source
  KAKENHI-PROJECT-21700413
[Presentation] Musashil新規標的doublecortinとの相互作用解析(Ihteraction analysis of the Musashil RNA-binding protein and a novel target Mrna, doublecortin)2009
- Author(s)
  堀澤健一, 今井貴雄, 岡野栄之, 柳川弘志
- Organizer
  第32回日本分子生物学会年会(MBSJ2009)4P-0096
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2009-12-12
- Data Source
  KAKENHI-PROJECT-21700413
[Presentation] RNA-binding protein Musashil inhibits let-7 miRNA activity2009
- Author(s)
  Takao Imai, Hironori Kawahara, Satoshi Kawase, Hideyuki Okano.
- Organizer
  第7回幹細胞シンポジウム
- Place of Presentation
  泉ガーデンギャラリー,東京
- Year and Date
  2009-05-15
- Data Source
  KAKENHI-PROJECT-21700413
[Presentation] Analysis of transcriptional regulation of musashil gene in neural stem cells2009
- Author(s)
  Satoshi Kawase, Takao Imai, Chikako Hara, Hideyuki Okano
- Organizer
  第7回幹細胞シンポジウム
- Place of Presentation
  泉ガーデンギャラリー,東京
- Year and Date
  2009-05-15
- Data Source
  KAKENHI-PROJECT-21700413
[Presentation] RNA結合蛋白質Musashilのlet-7 miRNA機能発現に対する制御2009
- Author(s)
  今井貴雄, 河原裕憲, 河瀬聡, 岡野栄之
- Organizer
  第32回日本分子生物学会年会(MBSJ2009)
- Place of Presentation
  パシフイコ横浜、横浜
- Year and Date
  2009-12-09
- Data Source
  KAKENHI-PROJECT-21700413
[Presentation] Acontribution of Musashil to the regulation by Lin-28 in blocking miRNA processing2009
- Author(s)
  Hironori Kawahara, Takao Imai, Hideyuki Okano
- Organizer
  第7回幹細胞シンポジウム
- Place of Presentation
  泉ガーデンギャラリー,東京
- Year and Date
  2009-05-15
- Data Source
  KAKENHI-PROJECT-21700413
[Presentation] 翻訳制御に関わるMusashi1とPABP1の相互作用と立体構造の解析(NMR approaches to elucidate the molecular mechanism of translation inhibition by Musashil and PABP1)2009
- Author(s)
  飯倉裕之, 田中志穂, 樋口敬介, 河原裕憲, 今井貴雄, 岡野栄之, 永田崇, 片平正人
- Organizer
  第32回日本分子生物学会年会(MBSJ2009)3P-0088
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2009-12-11
- Data Source
  KAKENHI-PROJECT-21700413
[Presentation] RNA-binding protein Musashil inhibits let-7 miRNA activity.2009
- Author(s)
  Imai T., Kawahara H., Kawase H., Okano H.
- Organizer
  第7回幹細胞シンポジウム
- Place of Presentation
  泉ガーデンギャラリー,東京
- Year and Date
  2009-05-15
- Data Source
  KAKENHI-PROJECT-21700413
[Presentation] 神経幹細胞におけるmusashi-1遺伝子の転写制御機構の解析(Analysis of transcriptional regulation of musashi-1 gene in neural stem cells)2009
- Author(s)
  河瀬聡, 今井貴雄, 原央子, 矢口邦雄, 糸原重美, 岡野栄之
- Organizer
  第32回日本分子生物学会年会(MBSJ2009)4p-0004
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2009-12-12
- Data Source
  KAKENHI-PROJECT-21700413
[Presentation] Analysis of transcriptional regulation of musashi1 gene in neural stem cells.2008
- Author(s)
  Satoshi Kawase, Takao Imai, Chikako Hara, Hideyuki Okano.
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2008-12-10
- Data Source
  KAKENHI-PROJECT-19700348
[Presentation] 神経系RNA結合蛋白質Musashi1はeIF4GとPABPの相互作用を阻害する(Neural RNA-binding protein Musashi1 inhibits translation initiation bycompeting with eIF4G for PABPs.)2008
- Author(s)
  河原裕憲、今井貴雄、今高寛晃、辻本雅文、松本健、岡野栄之
- Organizer
  第31回日本神経科学大会(Neuroscience 2008)
- Place of Presentation
  東京国際フォーラム
- Year and Date
  2008-07-10
- Data Source
  KAKENHI-PROJECT-19700348
[Presentation] Musashiタンパク質とPABPの相互作用の解析2008
- Author(s)
  樋口敬介、永田崇、河原裕憲、今井貴雄、岡野栄之、片平正人
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2008-12-11
- Data Source
  KAKENHI-PROJECT-19700348
[Presentation] Musashi蛋白質のRNA結合能と翻訳抑制の翻訳後制御2008
- Author(s)
  今井貴雄、菅田浩司、河原裕憲、河瀬聡、岡野栄之
- Organizer
  第31回日本神経科学大会
- Place of Presentation
  東京・東京国際フォーラム
- Year and Date
  2008-07-10
- Data Source
  KAKENHI-PROJECT-19700348
[Presentation] usashi蛋白質のRNA結合能と翻訳抑制の翻訳後制御(Posttranscriptionalregulation of Musashi1 RNA-binding activity and its translational control.)2008
- Author(s)
  今井貴雄、菅田浩司、河原裕憲、河瀬聡、岡野栄之
- Organizer
  第31回日本神経科学大会(Neuroscience2008)
- Place of Presentation
  東京国際フォーラム
- Year and Date
  2008-07-10
- Data Source
  KAKENHI-PROJECT-19700348
[Presentation] RNA-binding protein Musashi1 inhibits translation initiation by competing with eIF4G for PABP2008
- Author(s)
  Hironori Kawahara, Takao Imai, Hiroaki Imataka, Masafumi Tsujimoto, Ken Matsumoto, Hideyuki Okano 、Neural
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2008-12-12
- Data Source
  KAKENHI-PROJECT-19700348
[Presentation] RNA結合蛋白質Musashi1のlet-7 miRNA機能発現に対する制御2008
- Author(s)
  今井貴雄、河原裕憲、河瀬聡、岡野栄之
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会
- Place of Presentation
  神戸・ポートアイランド
- Year and Date
  2008-12-12
- Data Source
  KAKENHI-PROJECT-19700348
[Presentation] RNA結合蛋白質Musashi1のlet-7 miRNA機能発現に対する制御、4P-0719(BMB2008)2008
- Author(s)
  今井貴雄、河原裕憲、河瀬聡、岡野栄之
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会)
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2008-12-12
- Data Source
  KAKENHI-PROJECT-19700348
[Presentation] ロングレンジの距離情報に基づいたマルチドメイン蛋白質Musashi1と標的RNAの複合体の構造解析2008
- Author(s)
  大山貴子、永田崇、古川亜矢子、杉山孝司、真鶴司、今井貴雄、岡野栄之、山崎俊夫、片平正人
- Organizer
  第10回日本RNA学会年会
- Place of Presentation
  札幌市・札幌コンベンションセンター
- Year and Date
  2008-07-23
- Data Source
  KAKENHI-PROJECT-19700348
[Presentation] 神経幹細胞におけるmusashi遺伝子の転写制御解析(Analysis of transcriptionalregulation of musashi1 gene in neural stemcells.)2008
- Author(s)
  河瀬聡、今井貴雄、原央子、岡野栄之
- Organizer
  第31回日本神経科学大会(Neuroscience2008)
- Place of Presentation
  東京国際フォーラム
- Year and Date
  2008-07-10
- Data Source
  KAKENHI-PROJECT-19700348
[Presentation] Neural RNA-binding protein Musashi1 Inhibits Translational Initiation by Competing with eIF4G for PABP.2007
- Author(s)
  河原裕憲、今井貴雄、今高寛晃、辻本雅文、松本健、岡野栄之
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学大会合同大会
- Place of Presentation
  パシフィコ横浜、ヨコハマグランドインターコンチネンタルホテル
- Year and Date
  2007-12-13
- Data Source
  KAKENHI-PROJECT-19700348
[Presentation] RNA結合蛋白質Musashi1の新規標的RNAの同定2007
- Author(s)
  今井貴雄、河原裕憲、芝田晋介、河瀬聡、岡野栄之
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学大会合同大会
- Place of Presentation
  パシフィコ横浜、ヨコハマグランドインターコンチネンタルホテル
- Year and Date
  2007-12-13
- Data Source
  KAKENHI-PROJECT-19700348
[Presentation] RNA結合蛋白質Musashilの新規標的RNAの同定2007
- Author(s)
  今井貴雄, 河原裕憲, 芝田晋介, 河瀬聡, 岡野栄之
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学大会合同大会
- Place of Presentation
  パシフィコ横浜、ヨコハマグランドインターコンチネンタルホテル
- Year and Date
  2007-12-13
- Data Source
  KAKENHI-PROJECT-19700348
[Presentation] ロングレンジの構造情報を利用したMusashiタンパク質と標的RNAとの複合体の構造解析2007
- Author(s)
  大山貴子、大柄晶太、宮ノ入洋平、古川亜矢子、今井貴雄、岡野栄之、永田崇、片平正人
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学大会合同大会
- Place of Presentation
  パシフィコ横浜、ヨコハマグランドインターコンチネンタルホテル
- Year and Date
  2007-12-11
- Data Source
  KAKENHI-PROJECT-19700348
[Presentation] Musashi-1による胃特異的なm-Numb翻訳促進作用を介した胃粘膜修復機構
- Author(s)
  高橋哲史, 鈴木秀和, 今井貴雄, 土本寛二, 岡野栄之, 日比紀文
- Organizer
  第40回日本潰瘍学会/第14回国際潰瘍学会
- Place of Presentation
  東京、京王プラザホテル
- Data Source
  KAKENHI-PROJECT-24601016
[Presentation] MUSASHI1 POST-TRANSCRIPTIONALLY REGULATES THE GENE EXPRESSION IN NEURAL STEM/PROGENITOR CELLS AND GLIOMA.
- Author(s)
  Imai T., Muto J., Kawase S., Shibata S., Okano H.
- Organizer
  International Society for Stem Cell Research (ISSCR) 10th Annual Meeting
- Place of Presentation
  Pacifico Yokohama Conference Center, Yokohama, Japan
- Data Source
  KAKENHI-PROJECT-24601016
[Presentation] Musashi1 post-transcriptionally regulates the gene expression in neural stem/progenitor cells and glioma
- Author(s)
  今井貴雄, 武藤淳, 河瀬聡, 芝田晋介, 岡野栄之
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡、福岡国際会議場・マリンメッセ福岡
- Data Source
  KAKENHI-PROJECT-24601016

1. OZAWA Yoko (90265885)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. KURIHARA Toshihide (50365342)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. HORISAWA Kenichi (70424207)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. KAWAE Satoshi (80468496)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
5. NISHIMOTO Yoshinori (30398622)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. 芝田晋介 (70407089)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 岡野栄之 (60160694)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. 土居信英 (50327673)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 松崎有未

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 馬渕洋

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 中川真一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Imai Takao 今井 貴雄

IMAI TAKAO 今井 貴雄

IMAI Takao 今井 貴雄

Research Projects

Research Products

Co-Researchers

Development of pluripotent gene expression indicator using CRISPR/Cas9 genome editing and the study regarding tumorigenicity of human pluripotent stem cell-derived neural stem cells.Principal Investigator

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Analysis for a neural differentiation regulatory factor, Musashi1

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Establishment of the reporter stem cell lines capable of evaluating the cell influence by radiation.Principal Investigator

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Elucidation of the molecular mechanism for inhibition of let-7 miRNA function by RNA-binding protein Musashi1Principal Investigator

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The mechanism of photoreceptor cell differentiation to utilize in retinal regenerative therapy

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Identification of target RNAs for neural RNA-binding protein Musashi1Principal Investigator

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RNA結合蛋白質Musashiが介する神経幹細胞における翻訳調節の分子機構解明Principal Investigator

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[Journal Article] Rfx Transcription Factors Control Musashi1 Transcription in Mouse Neural Stem/Progenitor Cells.2014

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[Journal Article] Musashi-1 post-transcriptionally enhances phosphotyrosine-binding domain- containing m-Numb protein expression in regenerating gastric mucosa.2013

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[Journal Article] The long non-coding RNA nuclear-enriched abundant transcript 1_2 induces paraspeckle formation in the motor neuron during the early phase of amyotrophic lateral sclerosis2013

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[Journal Article] Cellular toxicity induced by the 26-kDa fragment and amyotrophic lateral sclerosis-associated mutant forms of TAR DNA-binding protein 43 in human embryonic stem cell-derived motor neurons.2013

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[Journal Article] RNA-Binding Protein Musashi1 Modulates Glioma Cell Growth through the Post-Transcriptional Regulation of Notch and PI(3) Kinase/Akt Signaling Pathways2012

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[Journal Article] RNA結合タンパク質による遺伝子制御と神経発生・神経機能2012

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[Journal Article] RNA結合タンパク質による遺伝子制御と神経発生・神経機能2012

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Imai Takao 今井貴雄

IMAI TAKAO 今井貴雄

IMAI Takao 今井貴雄