HASEI Tomohiro 長谷井友尋

Researcher Number	10388027
Other IDs
Affiliation (Current)	2025: 大阪医科薬科大学, 薬学部, 准教授
Affiliation (based on the past Project Information) *help	2021 – 2024: 大阪医科薬科大学, 薬学部, 准教授 2018 – 2020: 大阪薬科大学, 薬学部, 准教授 2015 – 2017: 京都薬科大学, 薬学部, 講師 2009 – 2014: 京都薬科大学, 薬学部, 助教 2007: Kyoto Pharmaceutical University, School of Pharmacy, Research Assistant 2006: 京都薬科大学, 薬学部, 助 2004 – 2005: 京都薬科大学, 薬学部, 助手
Review Section/Research Field	Principal Investigator Basic Section 63040:Environmental impact assessment-related / Environmental pharmacy Except Principal Investigator Environmental pharmacy / Environmental and hygienic pharmacy / Basic Section 64010:Environmental load and risk assessment-related
Keywords	Principal Investigator 大気 / エピジェネティクス / 環境 / 土壌 / エピジェネティック / 血糖 / ABAQ / アミノ酸 / 糖 / ヘテロサイクリックアミン … More / メイラード反応 / 遺伝毒性 / がん / 食品 / 糖尿病 / 栄養化学 … More Except Principal Investigator 大気 / soil / air / nitroarene / 土壌 / ニトロアレーン / タンパク質 / エンドトキシン / 変異原性 / 遺伝毒性 / 求電子ストレス / 付加体生成 / 酸化ストレス / 活性酸素 / 大気粒子 / 細菌 / アレルギー・喘息 / 大気汚染 / たんぱく質 / 喘息 / リポポリサッカライド / carcinogen / Ames test / 3, 6-dinitrobenzo[e]pyrene / mutagenicity / 3,6-dinitrobenzo[e]rene / 化学発がん物質 / エームステスト / 3,6-dinitrobenzo[e]pyrene / mutagen / genotoxicity / 変異原性物質 / 大気粉塵 / グルコース / トリプトファン / 小核試験 / 尿 / ABAQ / メイラード反応 / 糖尿病 / 栄養化学 Less

大気粉塵及び表層土壌のエピジェネティクス誘発活性の季節変動、地域特性及び粒径分布Principal Investigator
- Principal Investigator
  
  長谷井友尋
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 63040:Environmental impact assessment-related
- Research Institution
  Osaka Medical and Pharmaceutical University
Toxicity assessment and identification of contributing chemicals by simultaneous determination of oxidative and electrophilic stress derived from airborne particulate matters
- Principal Investigator
  
  鳥羽陽
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 64010:Environmental load and risk assessment-related
- Research Institution
  Nagasaki University
Seasonal fluctuation and regional characteristics of epigenetic induction via miRNA by airborne particlesPrincipal Investigator
- Principal Investigator
  
  Hasei Tomohiro
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 63040:Environmental impact assessment-related
- Research Institution
  Osaka Medical and Pharmaceutical University
  Osaka University of Pharmaceutical Sciences
Association of bioaerosol in outdoor air with asthma exacerbation
- Principal Investigator
  
  Watanabe Tetsushi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental and hygienic pharmacy
- Research Institution
  Kyoto Pharmaceutical University
Long-range transport and biological activity of inflammatry/allergic material
- Principal Investigator
  
  Watanabe Tetsushi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental and hygienic pharmacy
- Research Institution
  Kyoto Pharmaceutical University
Production and biological effects of ABAQ produced from the Maillard reaction and its relative substances in diabetesPrincipal Investigator
- Principal Investigator
  
  HASEI Tomohiro
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Environmental pharmacy
- Research Institution
  Kyoto Pharmaceutical University
Identification and risk assessment of novel mutagens isolated from diabetes model
- Principal Investigator
  
  WATANABE Tetsushi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental pharmacy
- Research Institution
  Kyoto Pharmaceutical University
Detection and risk assessment of carcinogenic compounds in ambient air and surface soil
- Principal Investigator
  
  WATANABE Tetsushi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental pharmacy
- Research Institution
  Kyoto Pharmaceutical University
Detection and genotoxicity of nitroarenes in ambient air and surface soil
- Principal Investigator
  
  WATANABE Tetsushi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental pharmacy
- Research Institution
  Kyoto Pharmaceutical University

All 2020 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2006 Other

All Journal Article Presentation

[Journal Article] 初年度教育「アカデミックスキル」の効果解析2020
- Author(s)
  倉田里穂、佐藤卓史、山野菜穂、妹尾　怜、堀　貴子、宮崎　誠、井上晴嗣、竹本宏輝、長谷井友尋、大桃善朗
- Journal Title
  
  大阪薬科大学紀要
  
  Volume: 15 Pages: 131-138
- Data Source
  KAKENHI-PROJECT-20K12195
[Journal Article] Seasonal Fluctuation of Endotoxin and Protein Concentrations in Outdoor Air in Sasebo, Japan2018
- Author(s)
  Mohammad Shahriar Khan, Souleymane Coulibaly, Maho Abe, Nami Furukawa, Yuuki Kubo, Yusuke Nakaoji, Kawase Yumi, Takahiro Matsumoto, Tomohiro Hasei, Yuya Deguchi, Hiroaki Nagaoka, Nobuyuki Yamagishi, Masanari Watanabe, Naoko Honda, Keiji Wakabayashi, Tetsushi Watanabe
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 41 Issue: 1 Pages: 115-122
- DOI
  10.1248/bpb.b17-00745
- NAID
  130006301298
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08396
[Journal Article] In vivo genotoxicity of a novel heterocyclic amine,aminobenzoazepinoquinolinone-derivative (ABAQ), produced by theMaillard reaction between glucose and l-tryptophan2014
- Author(s)
  Yukari Totsuka, Tetsushi Watanabe, Souleymane Coulibaly, Sae Kobayashi, Marina Nishizaki, Miho Okazaki, Tomohiro Hasei, Keiji Wakabayashi, Hitoshi Nakagama
- Journal Title
  
  Mutation Research/Genetic Toxicology and Environmental Mutagenesis
  
  Volume: 760 Pages: 48-55
- DOI
  10.1016/j.mrgentox.2013.12.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790132
[Journal Article] Isolation and Identification of a Novel Aromatic Amine Mutagen Produced by the Maillard Reaction2009
- Author(s)
  Rena Nishigaki, Tetsushi Watanabe, Tetsuya Kajimoto, Atsuko Tada, Takeji Takamura-Enya, Shigeki Enomoto, Haruo Nukaya, Yoshiyasu Terao, Atsushi Muroyama, Minoru Ozeki, Manabu Node, Tomohiro Hasei, Yukari Totsuka, Keiji Wakabayashi
- Journal Title
  
  Chemical Research in Toxicology
  
  Volume: 22 Pages: 1588-1593
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590139
[Journal Article] Determination of 3,6-dinitrobenzo[e]pyrene in surface soil and airborne particles by high-performance liquid chromatography with fluorescence detection2006
- Author(s)
  Tomohiro Hasei, et. al.
- Journal Title
  
  Journal of Chromatography A 1135
  
  Pages: 65-70
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590125
[Journal Article] Determination of 3, 6-Dinitrobenzo[e] pyrene in Surface Soil and Airborne Particles by High-performance Liquid Chromatography with Fluorescence Detection.2006
- Author(s)
  Tomohiro Hasei
- Journal Title
  
  Journal of Chromatography A 1135
  
  Pages: 65-70
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590125
[Journal Article] Determination of 3,6-dinitrobenzo〔e〕pyrene in surface soil and airborne particles by high-performance liquid chromatography with fluorescence detection2006
- Author(s)
  Tomohiro Hasei et al.
- Journal Title
  
  Journal of Chromatography A 1135
  
  Pages: 65-70
- Data Source
  KAKENHI-PROJECT-18590125
[Presentation] Seasonal Fluctuation of the Concentrations of Endotoxin, Protein and Ionic Substances in Outdoor Air and their Effect on Asthmatic Patients.2017
- Author(s)
  Mohammad Shahriar Khan, Nami Furukawa, Yuuki Kubo, Yusuke Nakaoji, Yumi Kawase, Tomohiro Hasei, Takahiro Matsumoto, Yoshitaka Yano, Yuya Deguchi, Hiroaki Nagaoka, Makoto Miura, Yukio Nagasaka, Nobuyuki Yamagishi, Tetsushi Watanabe
- Organizer
  フォーラム2017衛生薬学・環境トキシコロジー
- Data Source
  KAKENHI-PROJECT-17K08396
[Presentation] 西日本における大気中のタンパク質、エンドトキシン、イオン類の濃度の季節的変動と長距離輸送の影響.2017
- Author(s)
  渡辺徹志、Khan Mohammad Shahriar、古川奈美、久保裕希、中大路友亮、河瀬裕美、長谷井友尋、松本崇宏、出口雄也、長岡寛明、山岸伸行
- Organizer
  第58回大気環境学会
- Data Source
  KAKENHI-PROJECT-17K08396
[Presentation] Seasonal Fluctuation of Lipopolysaccharide on Airborne Particles and Relation with Asian Dust2016
- Author(s)
  8)Mohammad Shahriar Khan，Maho Abe，Nami Furukawa，Yuuki Kubo，Shigeharu Kitamura，Yusuke Nakaoji，Kawase Yumi，Tomohiro Hasei，Takahiro Matsumoto，Yuya Deguchi，Nobuyuki Yamagishi，Tetsushi Watanabe
- Organizer
  フォーラム2016衛生薬学・環境トキシコロジー
- Place of Presentation
  昭和大学（東京都品川区）
- Year and Date
  2016-09-10
- Data Source
  KAKENHI-PROJECT-26460178
[Presentation] 黄砂飛散と大気中のタンパク及びエンドトキシン濃度の関係2016
- Author(s)
  渡辺徹志、長谷井友尋
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜市
- Year and Date
  2016-03-29
- Data Source
  KAKENHI-PROJECT-26460178
[Presentation] 食品中の新規ヘテロサイクリックアミンABAQの分析2015
- Author(s)
  長谷井友尋、北野祐香、廣本麻里、川久保慶一、河内麻由美、渡辺徹志
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸
- Year and Date
  2015-03-28
- Data Source
  KAKENHI-PROJECT-24790132
[Presentation] 黄砂及び微小粒子状物質中のタンパク質及びLPSの解析2015
- Author(s)
  渡辺徹志、長谷井友尋
- Organizer
  フォーラム2015 衛生薬学・環境トキシコロジー
- Place of Presentation
  神戸市
- Year and Date
  2015-09-17
- Data Source
  KAKENHI-PROJECT-26460178
[Presentation] Ⅰ型及びⅡ型糖尿病ラット並びに正常ラット尿中における新規遺伝毒性物質ABAQの分析2015
- Author(s)
  北野祐香、隆杉桃子、田村友香、廣本麻里、蟹江静、川久保慶一、スレイマン・クゥリバリ、長谷井友尋、戸塚ゆ加里、若林敬二、渡辺徹志
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸
- Year and Date
  2015-03-28
- Data Source
  KAKENHI-PROJECT-24790132
[Presentation] メイラード反応によって生成する新規遺伝毒性物質ABAQのヒト尿中からの検出2014
- Author(s)
  長谷井友尋、川久保慶一、河内麻由美、渡辺徹志
- Organizer
  第3回創薬科学フロンテフィアシンポジウム
- Place of Presentation
  京都
- Year and Date
  2014-11-22
- Data Source
  KAKENHI-PROJECT-24790132
[Presentation] メイラード反応によって生成する新規化合物ABAQのin vivo遺伝毒性2013
- Author(s)
  長谷井友尋、クゥリバリ・スレイマン、戸塚ゆ加里、若林敬二、渡辺徹志
- Organizer
  フォーラム2013衛生薬学・環境トキシコロジー
- Place of Presentation
  福岡県福岡市
- Data Source
  KAKENHI-PROJECT-24790132
[Presentation] 新規遺伝毒性物質ABAQの糖尿病ラットにおける生成2012
- Author(s)
  長谷井友尋、竹中信絵、宮崎千尋、隆杉桃子、岡崎美帆、細田成美、田村有香、増田修一、戸塚ゆ加里、若林敬二、渡辺徹志
- Organizer
  生物分子システムに基づく創薬科学フロンティア研究成果発表会
- Place of Presentation
  京都市
- Year and Date
  2012-02-18
- Data Source
  KAKENHI-PROJECT-21590139
[Presentation] 新規遺伝毒性物質ABAQの糖尿病モデルラット体内における生成2012
- Author(s)
  細田成美、竹中信絵、宮崎千尋、隆杉桃子、長谷井友尋、若林敬二、増田修一、戸塚ゆ加里、渡辺徹志
- Organizer
  第62回日本薬学会近畿支部総会・大会
- Place of Presentation
  兵庫県西宮市
- Data Source
  KAKENHI-PROJECT-24790132
[Presentation] 新規メイラード反応生成物ABAQのin vivo遺伝毒性2012
- Author(s)
  岡崎美帆、細田成美、田村有香、クゥリバリスレイマン、長谷井友尋、渡辺徹志
- Organizer
  生物分子システムに基づく創薬科学フロンティア研究成果発表会
- Place of Presentation
  京都市
- Year and Date
  2012-02-18
- Data Source
  KAKENHI-PROJECT-21590139
[Presentation] メイラード反応生成物アミノベンゾアゼピノキノリノン誘導体の遺伝毒性2011
- Author(s)
  小林沙衣、西崎真理奈、岡崎美帆クゥリバリ・スレイマン、小関稔、梶本哲也、野出學、長谷井友尋、戸塚ゆ加里、川西優喜、八木孝司、若林敬二、渡辺徹志
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡市
- Year and Date
  2011-03-30
- Data Source
  KAKENHI-PROJECT-21590139
[Presentation] メイラード反応由来新規変異原性物質ABAQの生体内生成に関する研究2011
- Author(s)
  山田昌徳、島村裕子、戸塚ゆ加里、稲葉直之、クゥリバリ・スレイマン、田村友佳、長谷井友尋、若林敬二、渡辺徹志、増田修一
- Organizer
  第40回日本環境変異原学会
- Place of Presentation
  東京都千代田区
- Year and Date
  2011-11-22
- Data Source
  KAKENHI-PROJECT-21590139
[Presentation] 新規メイラード反応生成物ABAQのin vivo遺伝毒性2011
- Author(s)
  岡崎美帆、西崎真理奈、細田成美、長谷井友尋、渡辺徹志
- Organizer
  第61回日本薬学会近畿支部総会・大会
- Place of Presentation
  神戸市
- Year and Date
  2011-10-22
- Data Source
  KAKENHI-PROJECT-21590139
[Presentation] 新規メイラード反応生成物アミノアゼピノキノリノン誘導体の遺伝子毒性2010
- Author(s)
  小林沙衣、西崎真理奈、小関稔、梶本哲也、野出學、長谷井友尋、戸塚ゆ加里、若林敬二、渡辺徹志
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山市
- Year and Date
  2010-03-30
- Data Source
  KAKENHI-PROJECT-21590139
[Presentation] 生体内モデルメイラード反応による新規化合物ABAQの生成とその遺伝毒性2010
- Author(s)
  小林沙衣、西崎真理奈、小関稔、梶本哲也、野出學、長谷井友尋、川西優喜、八木孝司、戸塚ゆ加里、若林敬二、渡辺徹志
- Organizer
  難病克服を目指した分子基盤創薬科学の開拓成果発表会
- Place of Presentation
  京都市
- Year and Date
  2010-03-15
- Data Source
  KAKENHI-PROJECT-21590139
[Presentation] メイラード反応生成物アミノアゼピノキノリノン誘導体の遺伝毒性評価2010
- Author(s)
  小林沙衣、西崎真理奈、小関稔、梶本哲也、野出學、長谷井友尋、戸塚ゆ加里、若林敬二、渡辺徹志
- Organizer
  第39回日本環境変異原学会
- Place of Presentation
  つくば市
- Year and Date
  2010-11-17
- Data Source
  KAKENHI-PROJECT-21590139
[Presentation] メイラード反応生成物アミノアゼピノキノリノン誘導体の遺伝毒性評価2010
- Author(s)
  小林沙衣、西崎真理奈、小関稔、梶本哲也、野出學、長谷井友尋、戸塚ゆ加里、若林敬二、渡辺徹志
- Organizer
  第60回日本薬学会近畿支部総会・大会
- Place of Presentation
  枚方市
- Year and Date
  2010-10-30
- Data Source
  KAKENHI-PROJECT-21590139
[Presentation] メイラード反応生成物アミノアゼピノキノリノン誘導体の遺伝子毒性評価2009
- Author(s)
  小林沙衣、西崎真理奈、小関稔、梶本哲也、野出學、長谷井友尋、戸塚ゆ加里、若林敬二、渡辺徹志
- Organizer
  第59回日本薬学会近畿支部総会・大会
- Place of Presentation
  東大阪市
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-21590139
[Presentation] メイラード反応生成物アミノアゼピノキノリノン誘導体の遺伝子毒性評価2009
- Author(s)
  小林沙衣、西崎真理奈、小関稔、梶本哲也、野出學、長谷井友尋、渡辺徹志、戸塚ゆ加里、若林敬二
- Organizer
  第38回日本環境変異原学会
- Place of Presentation
  静岡市
- Year and Date
  2009-11-26
- Data Source
  KAKENHI-PROJECT-21590139
[Presentation] 大気微小粒子(PM2.5)及び粗大粒子中のタンパク質及びリポポリサッカライドの解析
- Author(s)
  渡辺徹志、山岸伸行、長谷井友尋他
- Organizer
  日本薬学会第135年回
- Place of Presentation
  神戸
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-26460178

1. WATANABE Tetsushi (90182930)

# of Collaborated Projects: 5 results

# of Collaborated Products: 18 results
2. 鳥羽陽 (50313680)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. HIRAYAMA Teruhisa (10121568)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. OZEKI Minoru (40465597)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
5. TOTSUKA Yukari (40373401)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
6. YAMAGISHI Nobuyuki (60298685)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. 松本崇宏 (30780431)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. 奥平桂一郎 (10425671)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 畑光彦 (00334756)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 唐寧 (90372490)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 古内正美 (70165463)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. DEGUCHI Yuya

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results

HASEI Tomohiro 長谷井 友尋

Research Projects

Research Products

Co-Researchers

大気粉塵及び表層土壌のエピジェネティクス誘発活性の季節変動、地域特性及び粒径分布Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Toxicity assessment and identification of contributing chemicals by simultaneous determination of oxidative and electrophilic stress derived from airborne particulate matters

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Seasonal fluctuation and regional characteristics of epigenetic induction via miRNA by airborne particlesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Association of bioaerosol in outdoor air with asthma exacerbation

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Long-range transport and biological activity of inflammatry/allergic material

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Production and biological effects of ABAQ produced from the Maillard reaction and its relative substances in diabetesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification and risk assessment of novel mutagens isolated from diabetes model

Principal Investigator

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Detection and risk assessment of carcinogenic compounds in ambient air and surface soil

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Detection and genotoxicity of nitroarenes in ambient air and surface soil

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[Journal Article] 初年度教育「アカデミックスキル」の効果解析2020

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[Journal Article] Seasonal Fluctuation of Endotoxin and Protein Concentrations in Outdoor Air in Sasebo, Japan2018

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[Journal Article] In vivo genotoxicity of a novel heterocyclic amine,aminobenzoazepinoquinolinone-derivative (ABAQ), produced by theMaillard reaction between glucose and l-tryptophan2014

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[Journal Article] Isolation and Identification of a Novel Aromatic Amine Mutagen Produced by the Maillard Reaction2009

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[Journal Article] Determination of 3,6-dinitrobenzo[e]pyrene in surface soil and airborne particles by high-performance liquid chromatography with fluorescence detection2006

HASEI Tomohiro 長谷井友尋