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YANAI Ayako  柳内 綾子

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柳内 綾子  ヤナイ アヤコ

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Researcher Number 10415961
Affiliation (Current) 2025: 公益財団法人朝日生命成人病研究所, その他部局等, 准教授(移行)
Affiliation (based on the past Project Information) *help 2010: 朝日生命成人病研究所, 主任研究員
2008: 財団法人朝日生命成人病研究所, 准教授
2007: 財団法人朝日生命成人病研究所, その他部局等, 准教授
Review Section/Research Field
Except Principal Investigator
Gastroenterology
Keywords
Except Principal Investigator
JNK / 動物モデル / 消化管 / 発がん / NF-κB / 炎症 / 癌 / 癌・動物
  • Research Projects

    (1 results)
  • Research Products

    (17 results)
  • Co-Researchers

    (3 People)
  •  Mechanism of inflammation-associated gastro-intestinal carcinogenesis

    • Principal Investigator
      MAEDA Shin
    • Project Period (FY)
      2007 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Yokohama City University
      The Institute for Adult Diseases, Asahi Life Foundation

All 2010 2009 2008 2007

All Journal Article Presentation

  • [Journal Article] IkappaB kinase beta regulates gastric carcinogenesis via IL-1α expression.2010

    • Author(s)
      Sakamoto K, Hikiba Y, Nakagawa H, Hayakawa Y, Yanai A, Akanuma M, Ogura K, Yoshida H, Hirata Y, Kaestner KH, Omata M, Maeda S.
    • Journal Title

      Gastroenterology 139

      Pages: 226-38

    • Data Source
      KAKENHI-PROJECT-19390205
  • [Journal Article] IKKβ/NF-κB Activation Controls the Development of Liver Metastasis via IL-6 Expression.2009

    • Author(s)
      Maeda S, Hikiba Y, Sakamoto K, Nakagawa H, Hirata Y, Hayakawa Y, Yanai A, Ogura K, Karin M, Omata M.
    • Journal Title

      Hepatology

      Volume: 50 Pages: 1851-60

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390205
  • [Journal Article] Constitutive NF-κB activation in colorectal carcinoma plays a key role in angiogenesis, promoting tumor growth.2009

    • Author(s)
      Sakamoto K, Maeda S, Hikiba Y, Nakagawa H, Hayakawa Y, Shibata W, Yanai A, Ogura K, Omata M.
    • Journal Title

      Clin Cancer Res 15

      Pages: 2248-2258

    • Data Source
      KAKENHI-PROJECT-19390205
  • [Journal Article] Constitutive NF-κB activation in colorectal carcinoma plays a key role in angiogenesis, promoting tumor growth2009

    • Author(s)
      Sakamoto K, Maeda S, Hikiba Y, Nakagawa H, Hayakawa Y, Shibata Y, Yanai A, Ogura K, Omata M.
    • Journal Title

      Clinical Cancer Research 15

      Pages: 2248-58

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390205
  • [Journal Article] Effectiveness of IkappaB kinase inhibitors in murine colitis-associated tumorigenesis.2009

    • Author(s)
      Hayakawa Y, Maeda S, Nakagawa H, Hikiba Y, Shibata W, Sakamoto K, Yanai A, Hirata Y, Ogura K, Muto S, Itai A, Omata M.
    • Journal Title

      J Gastroenterol

      Volume: 44 Pages: 935-943

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390205
  • [Journal Article] Effectiveness of IkappaB kinase inhibitors in murine colitis-associated tumorigenesis.2009

    • Author(s)
      Hayakawa Y, Maeda S, Nakagawa H, Hikiba Y, Shibata W, Sakamoto K, Yanai A, Hirata Y, Ogura K, Muto S, Itai A, Omata M.
    • Journal Title

      J Gastroenterol 44

      Pages: 935-943

    • Data Source
      KAKENHI-PROJECT-19390205
  • [Journal Article] IKKβ/NF-κB Activation Controls the Development of Liver Metastasis via IL-6 Expression.2009

    • Author(s)
      Maeda S, Hikiba Y, Sakamoto K, Nakagawa H, Hirata Y, Hayakawa Y, Yanai A, Ogura K, Karin M, Omata M.
    • Journal Title

      Hepatology 50

      Pages: 1851-1860

    • Data Source
      KAKENHI-PROJECT-19390205
  • [Journal Article] c-Jun NH2-terminal kinase 1 is a critical regulator for the development of gastric cancer in mice.2008

    • Author(s)
      Shibata W, Maeda S, Hikiba Y, Yanai A, Sakamoto K, Nakagawa H, Ogura K, Karin M, Omata M.
    • Journal Title

      Cancer Res 68

      Pages: 5031-5039

    • Data Source
      KAKENHI-PROJECT-19390205
  • [Journal Article] Activation of IkappaB kinase and NF-kappaB is essential for Helicobacter pylori-induced chronic gastritis in Mongolian gerbils.2008

    • Author(s)
      Yanai A, Maeda S, Shibata W, Hikiba Y, Sakamoto K, Nakagawa H, Ohmae T, Hirata Y, Ogura K, Muto S, Itai A, Omata M.
    • Journal Title

      Infect Immun 76

      Pages: 781-787

    • Data Source
      KAKENHI-PROJECT-19390205
  • [Journal Article] c-Jun NH2-terminal kinase 1 is a critical regulator for the development of gastric cancer in mice2008

    • Author(s)
      Shibata W, Maeda S, Hikiba Y, Yanai A, Sakamoto K, Nakagawa H, Ogura K, Karin M, Omata M.
    • Journal Title

      Cancer Research 68

      Pages: 5031-39

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390205
  • [Journal Article] Activation of Ikappa B kinase and NF-kappaB is essential for Helicobacter pylori-induced chronic gastritis in Mongolian gerbils2008

    • Author(s)
      Yanai A, Maeda S, Shibata W, Hikiba Y, Sakamoto K, Nakagawa H, ohmae T, Hirata Y, Ogura K, Muto S, Itai A, Omata M
    • Journal Title

      Infect Immun 76

      Pages: 781-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390205
  • [Journal Article] Deletion of ASK1 attenuates acetaminophen-induced liver injury by inhibiting JNK activation2008

    • Author(s)
      Nakagawa H, Maeda S, Hikiba Y, Ohmae T, Shibata W, Yanai A, Sakamoto K, Ogura K, Noguchi T, Karin M, Ichijo H, Omata M.
    • Journal Title

      Gastroenterology 135

      Pages: 1311-21

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390205
  • [Journal Article] Cutting edge:The IkappaB kinase(IKK)inhibitor, NEMO-binding domain peptide, bloks inflammatory injury in murine colitis2007

    • Author(s)
      Shibata W, Maeda S, Hikiba Y, Yanai A, Ohmae T, Sakamoto K, Nakagawa H, Ogura K, Omata M
    • Journal Title

      J Immunol 179

      Pages: 2681-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390205
  • [Journal Article] Cutting Edge : The I{kappa}B Kinase (IKK) Inhibitor, NEMO-Binding Domain Peptide, Blocks Inflammatory Injury in Murine Colitis.2007

    • Author(s)
      Shibata W, Maeda S, Hikiba Y, Yanai A, Ohmae T, Sakamoto K, Nakagawa H, Ogura K, Omata M.
    • Journal Title

      J Immunol 179

      Pages: 2681-2685

    • Data Source
      KAKENHI-PROJECT-19390205
  • [Journal Article] Essential roles of high mobility group box 1 in the development of marine colitis and colitis-associated cancer2007

    • Author(s)
      Maeda S, Hikiba Y, Shibata W, Ohmae T, Yanai A, Ogura K, Yamada S, Omata M
    • Journal Title

      Siochem Biophys Res Commun 360

      Pages: 394-400

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390205
  • [Presentation] c-Jun NH2-terminal kinase 1 is a criticalregulator for the development of chemical-induced gastric cancer in mice2008

    • Author(s)
      Maeda S, Shibata W, Hikiba Y, Yanai A, Sakamoto 1 K, Nakagawa H, Ogura K, Karin M, Omata M.
    • Organizer
      Digestive Disease Week
    • Place of Presentation
      San Diego
    • Data Source
      KAKENHI-PROJECT-19390205
  • [Presentation] c-Jun NH2-terminal kinase 1 is a criticalregulator for the development of chemical-induced gastric cancer in mice.2008

    • Author(s)
      Maeda S, Shibata W, Hikiba Y, Yanai A, Sakamotol K, Nakagawa H, Ogura K, Karin M, Omata M.
    • Organizer
      Digestive Disease Week
    • Data Source
      KAKENHI-PROJECT-19390205
  • 1.  MAEDA Shin (40415956)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 17 results
  • 2.  OGURA Keiji (50376456)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 17 results
  • 3.  SHIBATA Wataru (00435819)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 14 results

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