Maeda Shin 前田愼

… Alternative Names

Researcher Number	40415956
Other IDs
Affiliation (Current)	2021: 横浜市立大学, 医学研究科, 教授
Affiliation (based on the past Project Information) *help	2016 – 2020: 横浜市立大学, 医学研究科, 教授 2015: 横浜市立大学, 医学系研究科, 教授 2012 – 2015: 横浜市立大学, 医学(系)研究科(研究院), 教授 2010 – 2012: 横浜市立大学, 医学系研究科, 教授 2009 – 2012: 横浜市立大学, 医学研究科, 教授 … More
Review Section/Research Field	Principal Investigator Biological Sciences / Gastroenterology / Carcinogenesis / Tumor biology / Basic Section 53010:Gastroenterology-related Except Principal Investigator Pathological medical chemistry / Gastroenterology / Basic Section 53010:Gastroenterology-related / Biological Sciences / Obstetrics and gynecology / Complex Systems Disease Theory
Keywords	Principal Investigator 癌 / 炎症 / 肝癌 / NF-κB / 発がん / 胃癌 / 動物モデル / 動物 / 遺伝子 / ゲノム … More Except Principal Investigator 膵癌 / 癌 / 転写因子 / 免疫学 / 分子腫瘍学 / microRNA / K-ras / 癌化 / 核酸 / 胃癌 / オルガノイド / 腫瘍間質相互作用 / 遺伝子改変マウス / 血管新生阻害 / Kras / TGF-beta / CXCケモカイン / CXCR2 / 遺伝子 / 細胞・組織 / 発現制御 / 炎症発癌 / 炎症性発癌 / PAIP2 / レポーターマウス / 非コードRNA / ミトコンドリア / 非コードＲＮＡ / ＹＢ－１ / YB-1 / ウイルス / 感染症 / シグナル伝達 / インターフェロン / C型肝炎ウイルス / 自然免疫 / 持続感染 / レプリコン / PKR / p53 / Toll-like receptor 3 / RNA interference / Dicer / Virus / Infection / Immunology / Signal transduction / Interferon / 卵巣癌 / βカテニン / OGPプロモーター / Creリコンビナーゼ / モデルマウス / ovarian carcinoma / beta cathenine / OGP promoter / Cre recombinase / model mouse / 加齢 / 細胞老化 / SASP / 老化 / non-coding RNA / 発癌 / 内科 / 複雑系 / ヘテロクロマチン / RNA / 反復配列RNA / 反復配列 / トランスレーショナルリサーチ / 腫瘍バンク / ３次元初代培養 / 胃癌バンク / 次世代シークエンサー / 阻害剤ライブラリー / ３次元腫瘍バンク / 超音波内視鏡 / 胆道癌 / 3次元オルガノイド培養パネル / 網羅的遺伝子解析 / EUS-FNA / 膵臓癌 / 次世代型シークエンサー / ３次元オルガノイド培養パネル / 遺伝子変異 / 遺伝子発現 / 遺伝子変異解析 / 遺伝子発現解析 / ISX / 胃細菌叢 / 除菌 / 胃炎 / 腸上皮化生 / 肝臓癌 / 細胞死 / 幹細胞 / 肝細胞癌 / 化学療法 / 癌幹細胞化 / 不均一性 Less

ISXに着目した非H. pylori胃細菌叢除菌による胃発癌対策治療の確立Ongoing
- Principal Investigator
  
  須江聡一郎
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Yokohama City University
エピジェネティックな変化を基盤とする新規胃発癌モデルの構築Principal InvestigatorOngoing
- Principal Investigator
  
  前田愼
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Yokohama City University
肝細胞死により誘導される癌幹細胞化と癌悪性化のメカニズムOngoing
- Principal Investigator
  
  近藤正晃
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Yokohama City University
臨床検体の網羅的遺伝子解析による胃癌不均一性メカニズムの解明Ongoing
- Principal Investigator
  
  芝田渉
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Yokohama City University
Construction of a 3D tumor bank of pancreaticobiliary cancer for personalized medicine
- Principal Investigator
  
  Sugimori Kazuya
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Yokohama City University
Impairment of microRNA function and carcinogenetic risk by aging
- Principal Investigator
  
  OTSUKA MOTOYUKI
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  The University of Tokyo
Oncogenetic process by the complexed system due to heterochromatin-derived RNA
- Principal Investigator
  
  OTSUKA Motoyuki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Complex Systems Disease Theory
- Research Institution
  The University of Tokyo
Three-dimensional tumor bank for gastric cancer personalized medinine
- Principal Investigator
  
  Tamura Toshihide
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Yokohama City University
Analysis of signaling pathways for liver cancer stem cell maintenancePrincipal Investigator
- Principal Investigator
  
  MAEDA Shin
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Tumor biology
- Research Institution
  Yokohama City University
Multi-step carcinogenesis due to non-coding repetitive RNA expression
- Principal Investigator
  
  Otsuka Motoyuki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  The University of Tokyo
炎症発がんにおける腫瘍細胞および間質細胞の起源の同定と分子標的への応用Principal Investigator
- Principal Investigator
  
  前田愼
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Yokohama City University
Roles of NF-kappaB activation in gastrointestinal tumorigenesisPrincipal Investigator
- Principal Investigator
  
  MAEDA Shin
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Carcinogenesis
- Research Institution
  Yokohama City University
Chronic inflammation-induced mimRNA functional impairment may cause inflammation-associated tumorigenesis in gastroenterological organs.
- Principal Investigator
  
  OTSUKA Motoyuki
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  The University of Tokyo
The role of IRF transcription factor family in inflammation-associated tumorigenesis
- Principal Investigator
  
  TAMURA Tomohiko
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Yokohama City University
遺伝子改変マウス膵発癌モデルを用いた膵癌の腫瘍間質相互作用の解析
- Principal Investigator
  
  IJICHI Hideaki
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Mechanism of inflammation-associated gastro-intestinal carcinogenesisPrincipal Investigator
- Principal Investigator
  
  MAEDA Shin
- Project Period (FY)
  2007 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Yokohama City University
  The Institute for Adult Diseases, Asahi Life Foundation
胃炎症発がんのメカニズムの解析と分子標的治療への可能性の検討Principal Investigator
- Principal Investigator
  
  前田愼
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (Start-up)
- Research Field
  
  Gastroenterology
- Research Institution
  The Institute for Adult Diseases, Asahi Life Foundation
Study of ovarian carcinogenesis using mice models
- Principal Investigator
  
  OKUDA Tsuyoshi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Showa University
Treatment of advanced liver cancer targeting tumor and tumor-related markersPrincipal Investigator
- Principal Investigator
  
  MAEDA Shin, OMATA Masao
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Inhibition of innate immune system by hepatitis C virus
- Principal Investigator
  
  OMATA Masao
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Gastroenterology
- Research Institution
  The University of Tokyo

All 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006

All Journal Article Presentation

[Journal Article] Quantitative monitoring of circulating tumor DNA in patients with advanced pancreatic cancer undergoing chemotherapy2020
- Author(s)
  Sugimori M、Sugimori K、Tsuchiya H、Suzuki Y、Tsuyuki S, Yoshihiro、Hirotani A、Sanga K、Tozuka Y、Komiyama S、Sato T、Tezuka S、Goda Y、Irie K、Miwa H、Miura Yi、Ishii T、Kaneko T、Nagahama M、Shibata W、Nozaki A、Maeda S
- Journal Title
  
  Cancer Science
  
  Volume: 111 Pages: 266-278
- DOI
  10.1111/cas.14245
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09465
[Journal Article] Combination chemotherapy with gemcitabine and nab-paclitaxel for a metastatic pancreatic ductal adenocarcinoma patient undergoing hemodialysis2019
- Author(s)
  Kaneko Takashi、Sugimori Kazuya、Tozuka Yuichiro、Fukushima Taito、Okada Kazuya、Oka Hiroyuki、Okazaki Hiroshi、Maeda Shin
- Journal Title
  
  Clinical Journal of Gastroenterology
  
  Volume: 12 Pages: 484-489
- DOI
  10.1007/s12328-019-00976-w
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09465
[Journal Article] Helicobacter-induced gastric inflammation alters the properties of gastric tissue stem/progenitor cells2017
- Author(s)
  Wataru Shibata, Soichiro Sue, Sachiko Tsumura, Yasuaki Ishii, Takeshi Sato, Eri Kameta, Makoto Sugimori, HIroaki Yamada, Hiroaki Kaneko, Tomohiko Sasaki, Tomohiro Ishii, Toshihide Tamura, Masaaki Kondo, Shin Maeda
- Journal Title
  
  BMC Gastroenterol
  
  Volume: 17 Pages: 145-145
- DOI
  10.1186/s12876-017-0706-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09286, KAKENHI-PROJECT-16K19355
[Journal Article] A novel mouse model of intrahepatic cholangiocarcinoma induced by liver-specific Kras activation and Pten deletion.2016
- Author(s)
  Ikenoue T, Terakado Y, Nakagawa H, Hikiba Y, Fujii T, Matsubara D, Noguchi R, Zhu C, Yamamoto K, Kudo Y, Asaoka Y, Yamaguchi K, Ijichi H, Tateishi K, Fukushima N, Maeda S, Koike K, Furukawa Y.
- Journal Title
  
  Sci Rep
  
  Volume: 6 Pages: 23899-23899
- DOI
  10.1007/s10396-015-0685-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25290045
[Journal Article] Smyd5 plays pivotal roles in both primitive and definitive hematopoiesis during zebrafish embryogenesis.2016
- Author(s)
  Ikenoue T, Terakado Y, Nakagawa H, Hikiba Y, Fujii T, Matsubara D, Noguchi R, Zhu C, Yamamoto K, Kudo Y, Asaoka Y, Yamaguchi K, Ijichi H, Tateishi K, Fukushima N, Maeda S, Koike K, Furukawa Y
- Journal Title
  
  Scientific Report
  
  Volume: 印刷中 Pages: 1-11
- DOI
  10.1038/srep23899
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860206, KAKENHI-PROJECT-25280105, KAKENHI-PROJECT-25290045, KAKENHI-PROJECT-25460432, KAKENHI-PROJECT-26460425, KAKENHI-PROJECT-26461031, KAKENHI-PROJECT-26462136, KAKENHI-PROJECT-16K15422, KAKENHI-PROJECT-16K08672, KAKENHI-PROJECT-16K10558, KAKENHI-PROJECT-26860227, KAKENHI-PROJECT-15H04806
[Journal Article] Inhibition of autophagy exerts anti-colon cancer effects via apoptosis induced by p53 activation and ER stress.2015
- Author(s)
  Sakitani K, Hirata Y, Hikiba Y, Hayakawa Y, Ihara S, Suzuki H, Suzuki N, Serizawa T, Kinoshita H, Sakamoto K, Nakagawa H, Tateishi K, Maeda S, Ikenoue T, Kawazu S, Koike K.
- Journal Title
  
  BMC Cancer
  
  Volume: １５ Pages: 795-795
- DOI
  10.1186/s12885-015-1789-5
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26860538, KAKENHI-PROJECT-25290045
[Journal Article] Loss of liver E-cadherin induces sclerosing cholangitis and promotes carcinogenesis2014
- Author(s)
  Nakagawa H, Hikiba Y, Hirata Y, Font-Burgada J, Sakamoto K, Hayakawa Y, Taniguchi K, Umemura A, Kinoshita H, Sakitani K, Nishikawa Y, Hirano K, Ikenoue T, Ijichi H, Dhar D, Shibata W, Akanuma M, Koike K, Karin M, Maeda S.
- Journal Title
  
  Proc Natl Acad Sci USA
  
  Volume: 111 Pages: 1090-1090
- DOI
  10.1073/pnas.1322731111
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390092, KAKENHI-PROJECT-24390183, KAKENHI-PROJECT-25290045, KAKENHI-PROJECT-25670186, KAKENHI-PROJECT-25893042
[Journal Article] Promotion of DNA repair by nuclear IKKβ phosphorylation of ATM in response to genotoxic stimuli2013
- Author(s)
  Kei Sakamoto, et al.
- Journal Title
  
  Oncogene
  
  Volume: 32 Pages: 1854-1862
- DOI
  10.1038/onc.2012.192
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J11187, KAKENHI-PROJECT-22300317, KAKENHI-PROJECT-23370062, KAKENHI-PROJECT-24657092
[Journal Article] Promotion of DNA repair bynuclear IKKβ phosphorylation of ATM in response togenotoxic stimuli2013
- Author(s)
  Sakamoto K, Hikiba Y, Nakagawa H, Hirata Y, Hayakawa Y, Kinoshita H, Nakata W,Sakitani K, Takahashi R, Akanuma M, Kamata H, Maeda S
- Journal Title
  
  Oncogene
  
  Volume: 32 Pages: 1854-62
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300317
[Journal Article] Interleukin-6 mediates epithelial-stromal interactions and promotes gastric tumorigenesis2013
- Author(s)
  Kinoshita H, et al.
- Journal Title
  
  PLos One
  
  Volume: 12 Pages: 1-10
- DOI
  10.1371/journal.pone.0060914
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J11187, KAKENHI-PROJECT-22300317, KAKENHI-PROJECT-22590679, KAKENHI-PUBLICLY-23114508
[Journal Article] Apoptosis signal-regulating kinase-1inhibitor as a potent therapeutic drug for the treatment of gastric cancer2012
- Author(s)
  Hayakawa Y, Hirata Y, Sakitani K, Nakagawa H, Nakata W, Kinoshita H, Takahashi R, Takeda K, Ichijo H, Maeda S, Koike K
- Journal Title
  
  Cancer Sci
  
  Volume: 103 Pages: 2181-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300317
[Journal Article] Anti-tumor activity of the proteasome inhibitor bortezomibin gastric cancer2012
- Author(s)
  Nakata W, Hayakawa Y, Nakagawa H, Sakamoto K, Kinoshita H, Takahashi R,HirataY, Maeda S, Koike K
- Journal Title
  
  Int J Oncol
  
  Volume: 39 Pages: 1529-36
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300317
[Journal Article] Colon cancer-derived factors activate NF-κB in myeloid cells viaTLR2 to linkinflammation and tumorigenesis2012
- Author(s)
  Maeda S, Hikiba Y, Sakamoto K, Nakagawa H, Hirata Y, Hayakawa Y, Akanuma M
- Journal Title
  
  Mol Med Report
  
  Volume: 4 Pages: 1083-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300317
[Journal Article] Inhibiting Cxcr2 disrupts tumor-stromal interactions and improves survival in a mouse model of pancreatic ductal adenocarcinoma2011
- Author(s)
  Ijichi H, Chytil A, Gorska AE, Aakre ME, Bierie B, Tada M, Mohri D, Miyabayashi K, Asaoka Y, Maeda S, Ikenoue T, Tateishi K, Wright CV, Koike K, Omata M, Moses HL
- Journal Title
  
  J Clin Invest
  
  Volume: 121 Pages: 4106-17
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300317
[Journal Article] Colon cancer-derived factors activate NF-kB in myeloid cells via TLR2 to linkinflammation and tumorigenesis2011
- Author(s)
  Maeda S, Hikiba Y, Sakamoto K, Nakagawa H, Hirata Y, Hayakawa Y, Akanuma M
- Journal Title
  
  Mol Med Report
  
  Volume: 4 Pages: 1083-88
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300317
[Journal Article] Altered Composition of Fatty Acids Exacerbates Hepatotumorigenesis duringActivation of the Phosphatidylinositol 3-kinase Pathway2011
- Author(s)
  Kudo Y, Tanaka Y, Tateishi K, Yamamoto K, Yamamoto S, Mohri D, IsomuraY,Seto M, Nakagawa H, Asaoka Y, Tada M, Ohta M, Ijichi H, Hirata Y, Otsuka M,Ikenoue T, Maeda S, Shiina S, Yoshida H, Nakajima O, Kanai F, Omata M, Koike K
- Journal Title
  
  J Hepatol. J Hepatol
  
  Volume: 55 Pages: 1400-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300317
[Journal Article] Gastric Cancer Risk According to the Distribution of Intestinal Metaplasia and Neutrophil Infiltration2011
- Author(s)
  Sakitani K, Hirata Y, Watabe H, Yamada A, Sugimoto T, Yamaji Y, Yoshida H, Maeda S, Omata M, Koike K
- Journal Title
  
  J Gastroenterol Hepatol
  
  Volume: 26 Pages: 1570-75
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300317
[Journal Article] Colon cancer-derived factors activate NF-κB in myeloid cells via TLR2 to linkinflammation and tumorigenesis2011
- Author(s)
  Maeda S, Hikiba Y, Sakamoto K, Nakagawa H, Hirata Y, Hayakawa Y, Akanuma M
- Journal Title
  
  Mol Med Report
  
  Volume: 4 Pages: 1083-88
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23114508
[Journal Article] Anti-tumor activity of the proteasome inhibitor bortezomibin gastric cancer2011
- Author(s)
  Nakata W, Hayakawa Y, Nakagawa H, Sakamoto K, Kinoshita H, Takahashi R, Hirata Y, Maeda S, Koike K
- Journal Title
  
  Int J Oncol
  
  Volume: 39 Pages: 1529-36
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23114508
[Journal Article] Reducedexpression of RAS protein activator like-1 in gastric cancer2011
- Author(s)
  Seto M, Ohta M, Ikenoue T, Sugimoto T, Asaoka Y, Tada M, Mohri D, Kudo Y,Ijichi H, Tateishi K, Otsuka M, Hirata Y, Maeda S, Koike K, Omata M
- Journal Title
  
  Int J Cancer
  
  Volume: 128 Pages: 1293-302
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300317
[Journal Article] Gastric Cancer Risk According to the Distribution ofIntestinal Metaplasia and Neutrophil Infiltration2011
- Author(s)
  Sakitani K, Hirata Y, Watabe H, Yamada A, Sugimoto T, Yamaji Y, Yoshida H,Maeda S, Omata M, Koike K
- Journal Title
  
  J Gastroenterol Hepatol
  
  Volume: 26 Pages: 1570-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300317
[Journal Article] Apoptosis signal-regulating kinase 1 and cyclin D1 compose apositive feedback loop contributing to tumor growth in gastric cancer2011
- Author(s)
  Hayakawa Y, Hirata Y, Nakagawa H, Sakamoto K, Hikiba Y, Kinoshita H, Nakata W, Takahashi R, Tateishi K, Tada M, Akanuma M, Yoshida H, Takeda K, Ichijo H, Omata M, Maeda S, Koike K.
- Journal Title
  
  Proc Natl Acad Sci U S A
  
  Volume: 108 Pages: 780-785
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300317
[Journal Article] Apoptosissignal-regulating kinase 1 inhibits hepatocarcinogenesis by controlling thetumor-suppressing function of stress-activated mitogen-activated protein kinase2011
- Author(s)
  Nakagawa H, Hirata Y, Takeda K, Hayakawa Y, Sato T, Kinoshita H, Sakamoto K, Nakata W, Hikiba Y, Omata M, Yoshida H, Koike K, Ichijo H, Maeda S
- Journal Title
  
  Hepatology
  
  Volume: 54 Pages: 185-95
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300317
[Journal Article] Apoptosissignal-regulating kinase 1 inhibits hepatocarcinogenesisby controlling thetumor-suppressing function of stress-activated mitogen-activated protein kinase2011
- Author(s)
  Nakagawa H, Hirata Y, Takeda K, Hayakawa Y, Sato T, Kinoshita H, Sakamoto K, Nakata W, Hikiba Y, Omata M,Yoshida H, Koike K, Ichijo H, Maeda S
- Journal Title
  
  Hepatology
  
  Volume: 54 Pages: 185-95
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300317
[Journal Article] Gastric cancer risk according to the distribution ofintestinal metaplasia and neutrophil infiltration2011
- Author(s)
  Sakitani K, Hirata Y, Watabe H, Yamada A, Sugimoto T, Yamaji Y, Yoshida H, Maeda S, Omata M, Koike K
- Journal Title
  
  J Gastroenterol Hepatol
  
  Volume: 26 Pages: 1570-75
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23114508
[Journal Article] Altered composition of fatty acids exacerbates hepatotumorigenesis during activation ofthe phosphatidylinositol 3-kinase pathway2011
- Author(s)
  Kudo Y, Tanaka Y, Tateishi K, Yamamoto K, Yamamoto S, Mohri D, Isomura Y, SetoM, Nakagawa H, Asaoka Y, Tada M, Ohta M, Ijichi H, Hirata Y, Otsuka M, Ikenoue T, Maeda S, Shiina S, Yoshida H, Nakajima O, Kanai F, Omata M, Koike K
- Journal Title
  
  J Hepatol
  
  Volume: 55 Pages: 1400-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300317
[Journal Article] Anti-tumor activity of the proteasome inhibitor bortezomibin gastric cancer2011
- Author(s)
  Nakata W, Hayakawa Y, Nakagawa H, Sakamoto K, Kinoshita H, Takahashi R, Hirata Y, Maeda S, Koike K
- Journal Title
  
  Int J Oncol
  
  Volume: 39 Pages: 1529-36
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300317
[Journal Article] Apoptosis signal-regulating kinase 1 and cyclin D1compose a positive feedback loop contributing to tumor growth in gastric cancer.2011
- Author(s)
  Hayakawa Y, Hirata Y, Nakagawa H, Sakamoto K, Hikiba Y, Kinoshita H, NakataW, Takahashi R, Tateishi K, Tada M, Akanuma M, Yoshida H, Takeda K, Ichijo H,Omata M, Maeda S, KoikeK
- Journal Title
  
  Proc Natl Acad Sci U S A
  
  Volume: 8 Pages: 780-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300317
[Journal Article] IkappaB kinase beta regulates gastric carcinogenesis via IL-1α expression.2010
- Author(s)
  Sakamoto K, Hikiba Y, Nakagawa H, Hayakawa Y, Yanai A, Akanuma M, Ogura K, Yoshida H, Hirata Y, Kaestner KH, Omata M, Maeda S.
- Journal Title
  
  Gastroenterology 139
  
  Pages: 226-38
- Data Source
  KAKENHI-PROJECT-19390205
[Journal Article] Apoptosis Signal-Regulating Kinase 1 regulates colitis and colitis-associated tumorigenesis via the innate immune responses.2010
- Author(s)
  Hayakawa Y, Hirata Y, Nakagawa H, Sakamoto K, Hikiba Y, Otsuka M, Ijichi H, Ikenoue T, Tateishi K, Akanuma M, Ogura K, Yoshida H, Ichijo H, Omata M, Maeda S.
- Journal Title
  
  Gastroenterology
  
  Volume: 138 Pages: 1055-67
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390205
[Journal Article] Apoptosis Signal-Regulating Kinase 1 regulates colitis and colitis-associated tumorigenesis via the innate immune responses.2010
- Author(s)
  Hayakawa Y, Hirata Y, Nakagawa H, Sakamoto K, Hikiba Y, Otsuka M, Ijichi H, Ikenoue T, Tateishi K, Akanuma M, Ogura K, Yoshida H, Ichijo H, Omata M, Maeda S.
- Journal Title
  
  Gastroenterology 138
  
  Pages: 1055-1067
- Data Source
  KAKENHI-PROJECT-19390205
[Journal Article] IkappaB kinase beta regulates gastric carcinogenesis via IL-1α expression2010
- Author(s)
  Sakamoto K, Hikiba Y, Nakagawa H, Hayakawa Y, Yanai A, Akanuma M, Ogura K, Yoshida H, Hirata Y, Kaestner KH, Omata M, Maeda S
- Journal Title
  
  Gastroenterology
  
  Volume: 139 Pages: 226-38
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300317
[Journal Article] Constitutive NF-κB activation in colorectal carcinoma plays a key role in angiogenesis, promoting tumor growth.2009
- Author(s)
  Sakamoto K, Maeda S, Hikiba Y, Nakagawa H, Hayakawa Y, Shibata W, Yanai A, Ogura K, Omata M.
- Journal Title
  
  Clin Cancer Res 15
  
  Pages: 2248-2258
- Data Source
  KAKENHI-PROJECT-19390205
[Journal Article] Effectiveness of IkappaB kinase inhibitors in murine colitis-associated tumorigenesis.2009
- Author(s)
  Hayakawa Y, Maeda S, Nakagawa H, Hikiba Y, Shibata W, Sakamoto K, Yanai A, Hirata Y, Ogura K, Muto S, Itai A, Omata M.
- Journal Title
  
  J Gastroenterol 44
  
  Pages: 935-943
- Data Source
  KAKENHI-PROJECT-19390205
[Journal Article] Ikappa B kinasebeta/ nuclear factor-kappaB activation controls the development of liver metastasis by way of interleukin-6 expression2009
- Author(s)
  Maeda S, Hikiba Y, Sakamoto K, Nakagawa H, Hirata Y, Hayakawa Y, Yanai A, Ogura K, Karin M, Omata M.
- Journal Title
  
  Hepatology 50
  
  Pages: 1851-1860
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016016
[Journal Article] Constitutive NF-κB activation in colorectal carcinoma plays a key role in angiogenesis, promoting tumor growth2009
- Author(s)
  Sakamoto K, Maeda S, Hikiba Y, Nakagawa H, Hayakawa Y, Shibata Y, Yanai A, Ogura K, Omata M.
- Journal Title
  
  Clinical Cancer Research 15
  
  Pages: 2248-58
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390205
[Journal Article] Effectiveness of IkappaB kinase inhibitors in murine colitis-associated tumorigenesis.2009
- Author(s)
  Hayakawa Y, Maeda S, Nakagawa H, Hikiba Y, Shibata W, Sakamoto K, Yanai A, Hirata Y, Ogura K, Muto S, Itai A, Omata M.
- Journal Title
  
  J Gastroenterol
  
  Volume: 44 Pages: 935-943
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390205
[Journal Article] Serum IL-6 levels and the risk for hepatocarcinogenesis in chronic hepatitis C patients: An analysis based on gender differences.2009
- Author(s)
  Nakagawa H, Maeda S, Yoshida H, Tateishi R, Masuzaki R, Ohki T, Hayakawa Y, Kinoshita H, Yamakado M, Kato N, Shiina S, Omata M.
- Journal Title
  
  Int J Cancer 125
  
  Pages: 2264-2269
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016016
[Journal Article] IKKβ/NF-κB Activation Controls the Development of Liver Metastasis via IL-6 Expression.2009
- Author(s)
  Maeda S, Hikiba Y, Sakamoto K, Nakagawa H, Hirata Y, Hayakawa Y, Yanai A, Ogura K, Karin M, Omata M.
- Journal Title
  
  Hepatology 50
  
  Pages: 1851-1860
- Data Source
  KAKENHI-PROJECT-19390205
[Journal Article] IKKβ/NF-κB Activation Controls the Development of Liver Metastasis via IL-6 Expression.2009
- Author(s)
  Maeda S, Hikiba Y, Sakamoto K, Nakagawa H, Hirata Y, Hayakawa Y, Yanai A, Ogura K, Karin M, Omata M.
- Journal Title
  
  Hepatology
  
  Volume: 50 Pages: 1851-60
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390205
[Journal Article] Ikappa B kinasebeta/nuclear factor-kappaB activation controls the development of liver metastasis by way of interleukin-6 expression2009
- Author(s)
  Maeda S
- Journal Title
  
  Hepatology 50
  
  Pages: 1851-60
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016016
[Journal Article] c-Jun NH2-terminal kinase 1 is a critical regulator for the development of gastric cancer in mice.2008
- Author(s)
  Shibata W, Maeda S, Hikiba Y, Yanai A, Sakamoto K, Nakagawa H, Ogura K, Karin M, Omata M.
- Journal Title
  
  Cancer Res 68
  
  Pages: 5031-5039
- Data Source
  KAKENHI-PROJECT-19390205
[Journal Article] Activation of IkappaB kinase and NF-kappaB is essential for Helicobacter pylori-induced chronic gastritis in Mongolian gerbils.2008
- Author(s)
  Yanai A, Maeda S, Shibata W, Hikiba Y, Sakamoto K, Nakagawa H, Ohmae T, Hirata Y, Ogura K, Muto S, Itai A, Omata M.
- Journal Title
  
  Infect Immun 76
  
  Pages: 781-787
- Data Source
  KAKENHI-PROJECT-19390205
[Journal Article] c-Jun NH2-terminal kinase 1 is a critical regulator for the development of gastric cancer in mice2008
- Author(s)
  Shibata W, Maeda S, Hikiba Y, Yanai A, Sakamoto K, Nakagawa H, Ogura K, Karin M, Omata M.
- Journal Title
  
  Cancer Research 68
  
  Pages: 5031-39
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390205
[Journal Article] Deletion of apoptosis signal-regulating kinase 1 attenuates acetaminophen-induced liver injury by inhibiting C-Jun N-terminal kinase activation.2008
- Author(s)
  Nakagawa H, Maeda S, Hikiba Y, Ohmae T, Shibata W, Yanai A, Sakamoto K, Ogura K, Noguchi T, Karin M, Ichijo H, Omata M.
- Journal Title
  
  Gastroenterology 135
  
  Pages: 1311-1321
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016016
[Journal Article] Activation of Ikappa B kinase and NF-kappaB is essential for Helicobacter pylori-induced chronic gastritis in Mongolian gerbils2008
- Author(s)
  Yanai A, Maeda S, Shibata W, Hikiba Y, Sakamoto K, Nakagawa H, ohmae T, Hirata Y, Ogura K, Muto S, Itai A, Omata M
- Journal Title
  
  Infect Immun 76
  
  Pages: 781-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390205
[Journal Article] Deletion of ASK1 attenuates acetaminophen-induced liver injury by inhibiting JNK activation2008
- Author(s)
  Nakagawa H, Maeda S, Hikiba Y, Ohmae T, Shibata W, Yanai A, Sakamoto K, Ogura K, Noguchi T, Karin M, Ichijo H, Omata M.
- Journal Title
  
  Gastroenterology 135
  
  Pages: 1311-21
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390205
[Journal Article] Cutting edge:The IkappaB kinase(IKK)inhibitor, NEMO-binding domain peptide, bloks inflammatory injury in murine colitis2007
- Author(s)
  Shibata W, Maeda S, Hikiba Y, Yanai A, Ohmae T, Sakamoto K, Nakagawa H, Ogura K, Omata M
- Journal Title
  
  J Immunol 179
  
  Pages: 2681-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390205
[Journal Article] Cutting Edge : The I{kappa}B Kinase (IKK) Inhibitor, NEMO-Binding Domain Peptide, Blocks Inflammatory Injury in Murine Colitis.2007
- Author(s)
  Shibata W, Maeda S, Hikiba Y, Yanai A, Ohmae T, Sakamoto K, Nakagawa H, Ogura K, Omata M.
- Journal Title
  
  J Immunol 179
  
  Pages: 2681-2685
- Data Source
  KAKENHI-PROJECT-19390205
[Journal Article] Essential roles of high mobility group box 1 in the development of marine colitis and colitis-associated cancer2007
- Author(s)
  Maeda S, Hikiba Y, Shibata W, Ohmae T, Yanai A, Ogura K, Yamada S, Omata M
- Journal Title
  
  Siochem Biophys Res Commun 360
  
  Pages: 394-400
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390205
[Journal Article] Gender disparity in liver cancer due to sex differences in MyD88-dependent IL-6 production2007
- Author(s)
  Naugler WE, Sakurai T, Kim S, Maeda S, Kim K, Elsharkawy AM, Karin M
- Journal Title
  
  Science 317・5834
  
  Pages: 121-124
- Data Source
  KAKENHI-PROJECT-18591847
[Journal Article] A large noncoding RNA is a marker for murine hepatocellular carcinomas and a spectrum of human carcinomas2007
- Author(s)
  Lin R, Maeda S, Liu C, Karin M, Edgington TS
- Journal Title
  
  Oncogene 26・6
  
  Pages: 851-8
- Data Source
  KAKENHI-PROJECT-18591847
[Journal Article] A large noncoding RNA is a marker for murine hepatocellularcarcinomas and a spectrum of human carcinomas2007
- Author(s)
  Lin R, Maeda S, Liu C, Karin M, Edgington TS
- Journal Title
  
  Oncogene 26・6
  
  Pages: 851-858
- Data Source
  KAKENHI-PROJECT-18591847
[Journal Article] Loss of hepatic NF-kappa B activity enhances chemical hepatocarcinoge nesis through sustained c-Jun N-terminal kinase 1 activation2006
- Author(s)
  Sakurai T, Maeda S, Chang L, Karin M
- Journal Title
  
  Proc Natl Acad Sci U S A 103
  
  Pages: 10544-51
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591847
[Journal Article] Loss of hepatic NF-kappa B activity enhances chemical hepatocarcinogenesis through sustained c-Jun N-terminal kinase 1 activation2006
- Author(s)
  Sakurai T, Maeda S, Chang L, Karin M
- Journal Title
  
  Proc Natl Acad Sci U S A 103・28
  
  Pages: 10544-51
- Data Source
  KAKENHI-PROJECT-18591847
[Journal Article] Loss of hepatic NP-kappa B activity enhances chemical hepatocarcinogenesis through sustained c-Jun N-terminal kinase 1 activation2006
- Author(s)
  Sakurai, T, Maeda, S, Chang, L, Karin, M
- Journal Title
  
  Proc Natl Acad Sci U S A 103-28
  
  Pages: 10544-51
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591847
[Journal Article] The E3 ubiquitin ligase itch couples JNK activation to TNFalpha-induced cell death by inducing c-FLIP(L) turnover2006
- Author(s)
  Chang L, Kamata H, Solinas G, Luo JL, Maeda S, Venuprasad K, Liu YC, Karin M
- Journal Title
  
  Cell 124・3
  
  Pages: 601-13
- Data Source
  KAKENHI-PROJECT-18591847
[Presentation] 進行膵癌における腫瘍由来血中遊離遺伝子の定量的モニタリングの有用性の検討2019
- Author(s)
  杉森　慎，杉森　一哉，前田　愼ら．
- Organizer
  第105回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-17K09465
[Presentation] The quantitative monitoring of ct-DNA in patients with advanced PDAC undergoing chemotherapy．2019
- Author(s)
  Sugimori M, Sugimori K, Maeda S
- Organizer
  第27回日本消化器関連学会JDDW2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09465
[Presentation] CLINICAL UTILITY OF THE QUANTITATIVE MONITORING OF CIRCULATING TUMOR DNA IN PATIENTS WITH ADVANCED PDAC UNDERGOING CHEMOTHERAPY.2019
- Author(s)
  Sugimori M, Sugimori K, Jimbo C, Tsuyuki S, Kaneta Y, Hirotani A, Sanga K, Komiyama S, Sato T, Tezuka S, Goda Y, Irie K, Miwa H, Miura Y, Ishii T, Shibata W, Nozaki A, Maeda S
- Organizer
  Digestive Disease Week 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09465
[Presentation] CLINICAL UTILITY OF THE QUANTITATIVE MONITORING OF CIRCULATING TUMOR DNA IN PATIENTS WITH ADVANCED PDAC UNDERGOING CHEMOTHERAPY2019
- Author(s)
  Makoto Sugimori, Kazuya Sugimori, Shin Maeda, et al.
- Organizer
  DIGESTIVE DISEASE WEEK, Poster session, 2019.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09465
[Presentation] 進行膵癌における化学療法施行中の血中遊離遺伝子中KRAS変異遺伝子モニタリングの有用性の検討．2019
- Author(s)
  杉森慎，杉森一哉，露木翔，廣谷あかね，三箇克幸，佐藤健，手塚瞬，合田賢弘，入江邦泰，三輪治生，芝田渉，野﨑昭人，前田愼
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K09465
[Presentation] 進行膵癌における腫瘍由来血中遊離遺伝子の定量的モニタリングの有用性の検討．2019
- Author(s)
  杉森慎, 杉森一哉, 神保智彩, 中森義典, 露木翔, 金田義弘, 廣谷あかね, 三箇克幸, 戸塚雄一朗, 小宮山哲史, 佐藤健, 手塚瞬, 合田賢弘, 入江邦泰, 三輪治生, 三浦雄輝, 石井寛裕, 芝田渉, 野﨑昭人, 前田愼
- Organizer
  第105回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-17K09465
[Presentation] 膵腫瘍におけるゲノム解析-病態解明と臨床的意義 Digital PCRと次世代型シークエンサーを用いた膵腫瘍におけるゲノム診療の実践2018
- Author(s)
  杉森　慎，杉森　一哉，前田　愼ら．
- Organizer
  第49回日本膵臓学会大会
- Data Source
  KAKENHI-PROJECT-17K09465
[Presentation] 膵腫瘤に対するEUS-FNA　液状化検体細胞診を用いた効率的な検体処理法の検討2018
- Author(s)
  杉森一哉, 合田賢弘, 三箇克幸, 廣谷あかね, 手塚瞬, 入江邦泰, 三輪治生, 沼田和司, 小寺輝明, 稲山嘉明, 前田愼
- Organizer
  第49回日本膵臓学会大会
- Data Source
  KAKENHI-PROJECT-17K09465
[Presentation] Practice of Genome Diagnosis in Pancreatic Tumor2018
- Author(s)
  杉森　慎，杉森　一哉，前田　愼ら．
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K09465
[Presentation] 膵癌診断におけるdigital PCRを用いたKRAS変異スクリーニングの有効性の検討2018
- Author(s)
  杉森慎、前田愼
- Organizer
  第104回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-17K09465
[Presentation] Targeting DNA sequencing for advanced gastric carcinoma using next generation sequencing2017
- Author(s)
  Shibata W, Tsumura S, Sue S, Sato T, Kameta E, Sugimori M, Ishii Y, Yamada H, Kaneko H, Sasaki T, Ishii T, Tamura T, Kirikoshi H, Kondo M, Maeda S
- Organizer
  第89回　日本胃癌学会総会総会 oral presentation
- Data Source
  KAKENHI-PROJECT-16K09286
[Presentation] Targeted DNA sequencing for advanced gastric carcinoma using next generation sequencing2017
- Author(s)
  芝田渉、津村祥子、須江聡一郎、佐藤健、亀田英里、杉森慎、石井泰明、山田博昭、金子裕明、佐々木智彦、石井寛裕、田村寿英、桐越博之、近藤正晃、前田愼
- Organizer
  第８９回日本胃癌学会
- Place of Presentation
  広島国際会議場、広島県広島市
- Data Source
  KAKENHI-PROJECT-16K09286
[Presentation] 次世代シークエンサーを用いた胃癌クリニカルシークエンスの試み2017
- Author(s)
  芝田渉、須江聡一郎、佐藤健、亀田英里、杉森慎、石井泰明、山田博昭、金子裕明、佐々木智彦、石井寛裕、田村寿英、近藤正晃、前田愼
- Organizer
  JDDW 2017
- Data Source
  KAKENHI-PROJECT-16K09286
[Presentation] 高脂肪食負荷は肝臓癌発生の強力なプロモーターとして機能する2016
- Author(s)
  中馬誠、前田愼
- Organizer
  第１０２回日本消化器病学会総会
- Place of Presentation
  京王プラザホテル（東京）
- Year and Date
  2016-04-20
- Data Source
  KAKENHI-PROJECT-25290045
[Presentation] STAT3の活性化がHelicobacter属による胃上皮の増殖と炎症に寄与する2015
- Author(s)
  石井泰明,芝田渉,佐藤健,亀田英里,須江聡一郎,前田愼
- Organizer
  JDDW 2015　第23回日本消化器関連学会週間
- Place of Presentation
  グランドプリンスホテル新高輪（東京）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-25290045
[Presentation] 次世代シーケンサーを用いた非B非C肝細胞癌の網羅的遺伝子解析2015
- Author(s)
  守屋聡,沼田和司,中馬誠,福田浩之,近藤正晃,野崎昭人,前田愼
- Organizer
  JDDW 2015　第23回日本消化器関連学会週間
- Place of Presentation
  グランドプリンスホテル新高輪（東京）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-25290045
[Presentation] Nuclear IKK β Phosphorylates ATM in Response to Genotoxic Stimuli2012
- Author(s)
  Sakamoto K,Hikiba Y, Hayakawa Y,Hirata Y, Akanuma M, Maeda S
- Organizer
  Which Helps Cancer Cell to Survive DNA Damage
- Place of Presentation
  San Diego.USA.
- Year and Date
  2012-05-19
- Data Source
  KAKENHI-PROJECT-22300317
[Presentation] Ask1 Plays a Critical Role in H.pylori-induced Gastric Inflammation and Metaplasia2012
- Author(s)
  Hayakawa Y,Hirata Y, Nakagawa H, Sakitani K , Kinoshita H, Takahashi R,Nakata W, Sakamoto K, Akanuma M, Maeda S, Koike K
- Organizer
  DIGESTIVE DISEASE WEEK (DDW)
- Place of Presentation
  San Diego.USA
- Year and Date
  2012-05-20
- Data Source
  KAKENHI-PROJECT-22300317
[Presentation] KRAS もしくは BRAF 変異がもたらす抗癌剤負可時の大腸癌細胞のシグナル伝達の解析2012
- Author(s)
  坂本啓,平田喜裕,前田愼
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  ロイトン札幌(北海道)
- Year and Date
  2012-09-19
- Data Source
  KAKENHI-PROJECT-22300317
[Presentation] Loss ofIRF Signaling Contributes to the Development of Helicobacter Associated Gastric Carcinogenesis in Vivo2012
- Author(s)
  Shibata W, Yasuzaki H, Kubushiro Y,Hotta C, Tamura T, Maeda S
- Organizer
  DIGESTIVE DISEASE WEEK (DDW)
- Place of Presentation
  San Diego.USA
- Year and Date
  2012-05-19
- Data Source
  KAKENHI-PROJECT-22300317
[Presentation] Nuclear IKKβ phosphorylates ATM in response to genotoxic stimuli2012
- Author(s)
  Sakamoto K, Hikiba Y, Hirata Y, Akanuma M, Kamata H, Maeda S
- Organizer
  第34回日本分子生物学会年会, ワークショップ
- Place of Presentation
  パシフィコ横浜(神奈川県
- Year and Date
  2012-12-15
- Data Source
  KAKENHI-PROJECT-22300317
[Presentation] IRF1 欠損はヘリコバクター関連胃発癌に促進的に関与する2012
- Author(s)
  芝田渉,安崎弘晃,前田愼
- Organizer
  第54回日本消化器病学会大会
- Place of Presentation
  神戸国際展示場(兵庫県)
- Year and Date
  2012-10-10
- Data Source
  KAKENHI-PROJECT-22300317
[Presentation] Inflammation-and stress-related signaling pathways in gastric carciogenesis2011
- Author(s)
  Maeda S
- Organizer
  International Scientific Coordination Network(ISCN)Groupement de Recherche(GDRI)
- Place of Presentation
  フランス:Montpellier(招待講演)
- Year and Date
  2011-11-24
- Data Source
  KAKENHI-PROJECT-22300317
[Presentation] ヘリコバクターピロリ感染による発癌と炎症の役割2011
- Author(s)
  前田愼
- Organizer
  第97回日本消化器病学会総会
- Place of Presentation
  京王プラザホテル(東京都)
- Year and Date
  2011-05-14
- Data Source
  KAKENHI-PROJECT-22300317
[Presentation] Analysis of the Role of JNK and Therapeutic Effect of JNK Inhibition in Pancreatic Cancer2011
- Author(s)
  Takahashi R, Nakata W, Kinoshita H, Hayakawa Y, Nakagawa H, Ijichi H, Hirata Y, Maeda S, Koike K
- Organizer
  Digestive Disease Week 2011
- Place of Presentation
  アメリカ:Chicago
- Year and Date
  2011-05-07
- Data Source
  KAKENHI-PROJECT-22300317
[Presentation] ヘリコバクターピロリ感染による発癌と炎症の役割2011
- Author(s)
  前田愼
- Organizer
  第97回日本消化器病学会総会シンポジウム 7 (ヘリコバクターピロリ感染症の徹底検証)
- Place of Presentation
  京王プラザホテル(東京都).
- Year and Date
  2011-05-14
- Data Source
  KAKENHI-PROJECT-22300317
[Presentation] DNA 損傷により惹起される核内 IKKβ による ATM リン酸化と DNA 修復促進2011
- Author(s)
  坂本啓, 早河翼, 中田和智子, 平田喜裕, 前田愼
- Organizer
  第70回日本癌学会学術総
- Place of Presentation
  名古屋国際会議場(愛知県)
- Year and Date
  2011-10-05
- Data Source
  KAKENHI-PROJECT-22300317
[Presentation] Interleukin-6(IL-6)Plays an Important Role in Epithelial-Stromal Interactionand Promotes Gastric Tumorigenesis2011
- Author(s)
  Kinoshita H, Hirata Y, Nakagawa H, Sakamoto K, Hayakawa Y, Takahashi R, Nakata W, Sakitani K, Hikiba Akanuma M, Maeda S, Koike K
- Organizer
  Digestive Disease Week 2011
- Place of Presentation
  アメリカ:Chicago
- Year and Date
  2011-11-19
- Data Source
  KAKENHI-PROJECT-22300317
[Presentation] 胃発癌におけるSDF-1/CXCR4シグナル経路の役割2011
- Author(s)
  芝田渉, 前田愼
- Organizer
  第19回浜名湖シンポジウム
- Place of Presentation
  アクトシティー浜松コングレスセンター(静岡県)
- Year and Date
  2011-12-24
- Data Source
  KAKENHI-PUBLICLY-23114508
[Presentation] 炎症と胃発癌2011
- Author(s)
  前田愼
- Organizer
  第100回日本病理学会総会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2011-04-29
- Data Source
  KAKENHI-PROJECT-22300317
[Presentation] Nuclear IKK β phosphorylates ATM in response to genotoxic stimuli, which promotes DNA reqair2011
- Author(s)
  Sakamoto K, Hikiba Y, Hirata Y, Akanuma M, Kamata H, Maeda S
- Organizer
  The 34^<th> Annual Meeting of the Molecular Biology Society of Japan
- Place of Presentation
  パシフィコ横浜(横浜市)
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PROJECT-22300317
[Presentation] Analysis of the role of JNK and therapeutic effect of JNK inhibition in pancreatic cancer2011
- Author(s)
  Takahashi R, Nakata W, Kinoshita H, Hayakawa Y, Nakagawa H, Ijichi H, Hirata Y, Maeda S, Koike K
- Organizer
  DIGESTIVE DISEASE WEEK (DDW)
- Place of Presentation
  Chicago. USA.
- Year and Date
  2011-05-07
- Data Source
  KAKENHI-PROJECT-22300317
[Presentation] Inflammation-and stress-related signaling pathways in gastriccarcinogenesis2011
- Author(s)
  Maeda S
- Organizer
  International Scientific Coordination Network (ISCN) Groupement de Recherche (GDRI)
- Place of Presentation
  Montpellier.FRANCE
- Year and Date
  2011-11-24
- Data Source
  KAKENHI-PROJECT-22300317
[Presentation] 炎症と胃発癌2011
- Author(s)
  前田愼
- Organizer
  第100回日本病理学会総会シンポジウム 3 (感染・炎症と胃癌)
- Place of Presentation
  パシフィコ横浜(神奈川県).
- Year and Date
  2011-04-29
- Data Source
  KAKENHI-PROJECT-22300317
[Presentation] Interleukin-6 (IL-6) plays an important role in epithelial-stromal interactionand promotes gastric tumorigenesis2011
- Author(s)
  Kinoshita H, Hirata Y, Nakagawa H, Sakamoto K, Hayakawa Y, Takahashi R,Nakata W, Sakitani K, Hikiba Y, Akanuma M, Maeda S, Koike K
- Organizer
  DIGESTIVE DISEASE WEEK (DDW)
- Place of Presentation
  Chicago.USA
- Year and Date
  2011-05-10
- Data Source
  KAKENHI-PROJECT-22300317
[Presentation] 胃癌に対するプロテアソーム阻害薬(bortezomib)の効果に関する検討.2010
- Author(s)
  中田和智子,早河翼,中川勇人,平田喜裕,小池和彦,前田愼
- Organizer
  第18回日本消化器関連学会週間(JDDW 2010)
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2010-10-13
- Data Source
  KAKENHI-PROJECT-22300317
[Presentation] Apoptosis Signal-Regulating kinase 1(ASK1)Regulates Colitis andColitis-Associated Tumorigenesis via the lnnate lmmune Responses2010
- Author(s)
  Hayakawa Y, Hirata Y, Nakagawa H, Sakamoto K, Hikiba Y,Yanai A, Akanuma M, Ogura K, Yoshida H, Omata M, Maeda S.
- Organizer
  DIGESTIVE DISEASE WEEK 2010
- Place of Presentation
  New Orleans.USA.
- Year and Date
  2010-05-04
- Data Source
  KAKENHI-PROJECT-22300317
[Presentation] Requirement for IKKB in a Mouse Model of Pancreatic Ductal Adenocarcinoma2010
- Author(s)
  Maeda S, Hikiba Y, Sakamoto K, Okamoto M Nakagawa H, Hirata Y, Hayakawa Y, Nakata W, Ijichi H, Omata M
- Organizer
  Digestive Disease Week
- Place of Presentation
  New Orleans, USA
- Year and Date
  2010-05-07
- Data Source
  KAKENHI-PROJECT-22300317
[Presentation] Requirement for IKKB in a Mouse Modelof Pancreatic Ductal Adenocarcinoma2010
- Author(s)
  Maeda S, Hikiba Y, Sakamoto K, Okamoto M Nakagawa H, Hirata Y, Hayakawa Y, Nakata W, Ijichi H, Omata M
- Organizer
  DIGESTIVE DISEASE WEEK 2010
- Place of Presentation
  New Orleans. USA
- Year and Date
  2010-05-03
- Data Source
  KAKENHI-PROJECT-22300317
[Presentation] microRNA maychinery構成因子DDX20の発現低下に伴う microRNA機能の減弱によって惹起される肝発癌経路の同定2010
- Author(s)
  大塚基之、高田朱弥、小島健太郎、前田愼、立石敬介、池上恒雄、平田善裕、建石良介、椎名秀一朗、吉田晴彦、小池和彦
- Organizer
  臨床分子医学会
- Place of Presentation
  東京国際フォーラム(東京都)
- Year and Date
  2010-04-10
- Data Source
  KAKENHI-PROJECT-22390058
[Presentation] Role of NF-kB in Controlling Citrobacter rodentium-Induced Colitis2010
- Author(s)
  Hirata Y, Hayakawa Y, Nakagawa H, Nakata W, Sakamoto K, Omata M, MaedaS
- Organizer
  DIGESTIVE DISEASE WEEK
- Place of Presentation
  New Orleans.USA
- Year and Date
  2010-05-04
- Data Source
  KAKENHI-PROJECT-22300317
[Presentation] 胃癌に対するプロテアソーム阻害薬(bortezomib) の効果に関する検討2010
- Author(s)
  中田和智子,早河翼,中川勇人,平田喜裕,小池和彦,前田愼
- Organizer
  第69回日本癌学会学術総会がん征圧へ向けての知の統合(新規分子標的薬(3))
- Place of Presentation
  大阪国際会議場(大阪府).
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-22300317
[Presentation] 肝発がんにおける IKK/NF-KBシグナル伝達経路の働き2010
- Author(s)
  前田愼
- Organizer
  第69回日本癌学会学術総会がん征圧へ向けての知の統合(MV2 JCA ・モヴェルネ賞)
- Place of Presentation
  大阪国際会議場(大阪府)
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-22300317
[Presentation] Apoptosis signal-regulating kinase 1(ASK1)は JNK-Bim 経路を介したアポトーシスを誘導し肝発癌を抑制する2010
- Author(s)
  中川勇人,平田喜裕,早河翼,木下裕人,坂本啓,引場陽子,高橋良太,中田和智子,崎谷康介,小池和彦,小俣政男,前田愼
- Organizer
  国際科学振興財団フォーラム第18回浜名湖シンポジウム
- Place of Presentation
  アクトシティ浜松コングレスセンター (静岡県)
- Year and Date
  2010-12-25
- Data Source
  KAKENHI-PROJECT-22300317
[Presentation] 膵がん発生における IKKbeta の役割の検討2010
- Author(s)
  前田愼,坂本啓,中川勇人,早河翼,平田喜裕
- Organizer
  第69回日本癌学会学術総会がん征圧へ向けての知の統合(動物発がんモデル(1))
- Place of Presentation
  大阪国際会議場(大阪府)
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-22300317
[Presentation] The Impact of IkappaB Kinase Beta in Gastric Carcinogenesis2010
- Author(s)
  Sakamoto K, Hikiba Y, Nakagawa H, Hayakawa Y, Yanai A, Hirata Y, OguraK, Akanuma M, Maeda S
- Organizer
  DIGESTIVE DISEASE WEEK 2010
- Place of Presentation
  New Orleans. USA.
- Year and Date
  2010-05-04
- Data Source
  KAKENHI-PROJECT-22300317
[Presentation] Serum IL-6 levels and the risk of hepatocarcinogenesis in chronic hepatitis C patients2009
- Author(s)
  Nakagawa H, Maeda S, Yoshida H, Tateishi R, Masuzaki R, Ohki T, Hayakawa Y, Kinoshita H, Yamakado M, Kato N, Shiina S, Omata M.
- Organizer
  DDW 2009
- Place of Presentation
  Chicago
- Year and Date
  2009-06-01
- Data Source
  KAKENHI-PROJECT-17016016
[Presentation] Colon cancer-derived factors activate NF-κB in myeloid cells via TLR2 to link inflammation and tumorigenesis2009
- Author(s)
  Shin Maeda, Yohko Hikiba, Kei Sakamoto, Hayato Nakagawa, Yoku Hayakawa, Yoshihiro Hirata, Keiji Ogura, Masao Omata
- Organizer
  Digestive Disease Week
- Place of Presentation
  Chicago
- Year and Date
  2009-05-05
- Data Source
  KAKENHI-PROJECT-19390205
[Presentation] Diagnosis of intrahepatic metastasis and multicentric carcinogenesis in the patients with hepatocellular carcinoma by Loss of heterozygosity analysis using taqman SNP genotyping assays2009
- Author(s)
  Asaoka Y, Tanaka Y, Nakagawa H, Masuzaki R, Tada M, Tateishi R, Ijichi H, Ikenoue T, Maeda S, Yoshida H, Kawabe T, Omata M.
- Organizer
  DDW
- Place of Presentation
  Chicago
- Year and Date
  2009-06-01
- Data Source
  KAKENHI-PROJECT-17016016
[Presentation] Masao Omata Colon cancer-derived factors activate NF-κB in myeloid cells via TLR2 to link inflammation and tumorigenesis2009
- Author(s)
  Shin Maeda, Yohko Hikiba, Kei Sakamoto, Hayato Nakagawa, Yoku Hayakawa, Yoshihiro Hirata, Keiji Ogura
- Organizer
  Digestive Disease Week
- Place of Presentation
  Chicago
- Year and Date
  2009-05-05
- Data Source
  KAKENHI-PROJECT-19390205
[Presentation] Taqmanプローブを用いたLOH解析による再発肝癌のクロナリティーに関する検討2009
- Author(s)
  浅岡良成、田中康雄、中川勇人、増崎亮太、多田素久、建石良介、伊地知秀明、池上恒雄、前田愼、吉田晴彦、小俣政男
- Organizer
  JDDW 2009
- Place of Presentation
  京都
- Year and Date
  2009-10-15
- Data Source
  KAKENHI-PROJECT-17016016
[Presentation] c-Jun NH2-terminal kinase 1 is a criticalregulator for the development of chemical-induced gastric cancer in mice2008
- Author(s)
  Maeda S, Shibata W, Hikiba Y, Yanai A, Sakamoto 1 K, Nakagawa H, Ogura K, Karin M, Omata M.
- Organizer
  Digestive Disease Week
- Place of Presentation
  San Diego
- Data Source
  KAKENHI-PROJECT-19390205
[Presentation] c-Jun NH2-terminal kinase 1 is a criticalregulator for the development of chemical-induced gastric cancer in mice.2008
- Author(s)
  Maeda S, Shibata W, Hikiba Y, Yanai A, Sakamotol K, Nakagawa H, Ogura K, Karin M, Omata M.
- Organizer
  Digestive Disease Week
- Data Source
  KAKENHI-PROJECT-19390205
[Presentation] アセトアミノフェン肝障害におけるApotosis signal-regulating kinase1(ASK1)-JNK2008
- Author(s)
  中川勇人、前田愼、小俣政男
- Organizer
  経路の関与JDDW
- Place of Presentation
  東京
- Year and Date
  2008-10-03
- Data Source
  KAKENHI-PROJECT-17016016
[Presentation] Deletion of apoptosis signal-regulating kinase 1 (ASK1) attenuates acetaminophen-induced liver injury by inhibiting prolonged JNK activation2008
- Author(s)
  Nakagawa H, Maeda S, Sakamoto K, Hayakawa Y, Ogura K, Omata M.
- Organizer
  DDW
- Place of Presentation
  San Diego
- Year and Date
  2008-05-20
- Data Source
  KAKENHI-PROJECT-17016016
[Presentation] 消化管癌発生、増殖におけるC-Jun N-terminal kinaseの役割2007
- Author(s)
  前田愼、芝田渉、小俣政男
- Organizer
  Japan Digestive Disease Week(JDDW)
- Place of Presentation
  神戸
- Year and Date
  2007-10-20
- Data Source
  KAKENHI-PROJECT-19390205
[Presentation] 消化管癌発生2007
- Author(s)
  前田愼、芝田渉、小俣政男
- Organizer
  増殖におけるC-Jun N-terminal kinaseの役割 Japan Digestive Disease Week (JDDW)
- Place of Presentation
  神戸
- Year and Date
  2007-10-20
- Data Source
  KAKENHI-PROJECT-19390205

1. OTSUKA Motoyuki (90518945)

# of Collaborated Projects: 6 results

# of Collaborated Products: 4 results
2. SHIBATA Wataru (00435819)

# of Collaborated Projects: 5 results

# of Collaborated Products: 27 results
3. IJICHI Hideaki (70463841)

# of Collaborated Projects: 4 results

# of Collaborated Products: 9 results
4. TATEISHI Keisuke (20396948)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
5. OMATA Masao (90125914)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
6. KANAI Fumihiko (70334399)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 須江聡一郎 (00738619)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
8. ENOMOTO Nobuyuki (20251530)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. SASAKI Shigeru (10305229)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. TANAKA Yasuo (40422290)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
11. OGURA Keiji (50376456)

# of Collaborated Projects: 1 results

# of Collaborated Products: 21 results
12. YANAI Ayako (10415961)

# of Collaborated Projects: 1 results

# of Collaborated Products: 17 results
13. TAMURA Tomohiko (50285144)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. YANAI Hideyuki (70431765)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. HOTTA Chie (80363810)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. KUROTAKI Daisuke (10568455)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. KATO Naoya (90313220)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. OKUDA Tsuyoshi (60407434)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. SASAKI Nobuya (20302614)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. Tamura Toshihide (70760065)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
21. Sugimori Kazuya (20448666)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
22. 吉田晴彦 (60240305)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
23. 近藤正晃 (60511615)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 金子裕明 (20760078)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. YAMAGUCHI Kiyoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. YAMAGUCHI Rui

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. MATSYBARA Daisuk

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. FUKUSHIMA Noriyoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. IKENOUE Tsuneo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. ASAOKA Yoshinari

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. HIRATA Yoshihiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
32. 西川祐司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
33. 小池和彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
34. 中川勇人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
35. 古川洋一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
36. 藤井智明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
37. 関谷剛男

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
38. 鎌田英明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Maeda Shin 前田 愼

MAEDA Shin 前田 愼

前田 慎 マエダ シン

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ISXに着目した非H. pylori胃細菌叢除菌による胃発癌対策治療の確立Ongoing

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エピジェネティックな変化を基盤とする新規胃発癌モデルの構築Principal InvestigatorOngoing

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肝細胞死により誘導される癌幹細胞化と癌悪性化のメカニズムOngoing

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臨床検体の網羅的遺伝子解析による胃癌不均一性メカニズムの解明Ongoing

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Analysis of signaling pathways for liver cancer stem cell maintenancePrincipal Investigator

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炎症発がんにおける腫瘍細胞および間質細胞の起源の同定と分子標的への応用Principal Investigator

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Roles of NF-kappaB activation in gastrointestinal tumorigenesisPrincipal Investigator

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Maeda Shin 前田愼

MAEDA Shin 前田愼

前田慎マエダシン