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Tanaka Yasuo  田中 康雄

… Alternative Names

TANAKA YASUO  田中 康雄

TANAKA Yasuo  田中 康雄

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Researcher Number 40422290
Other IDs
  • ORCIDhttps://orcid.org/0000-0002-2917-3365
Affiliation (Current) 2022: 東京大学, 医学部附属病院, 届出研究員
Affiliation (based on the past Project Information) *help 2018 – 2021: 東京大学, 医学部附属病院, 助教
2017: 東京大学, 医学部附属病院, 特任講師
2012 – 2016: 東京大学, 医学部附属病院, 助教
2009: 東京大学, 医学部附属病院, 寄附講座教員
2008: 東大, 医学部附属病院 … More
2007 – 2008: The University of Tokyo, 医学部附属病院, 寄付講座教員
2007: 東京大学, 医学部・附属病院, 寄付講座教員(助教担当)
2007: 東京大学, 医学部附属病院, 寄附講座教員
2006 – 2007: 東京大学, 医学部附属病院, 寄付講座教員(助教担当)
2006: 東京大学, 医学部附属病院, 寄付講座教員(助教相当) Less
Review Section/Research Field
Principal Investigator
Gastroenterology / Basic Section 53010:Gastroenterology-related
Except Principal Investigator
Gastroenterology / Biological Sciences / Basic Section 53010:Gastroenterology-related
Keywords
Principal Investigator
HBV / HBx / HBV Xタンパク / ユビキチン・プロテアソーム系 / ユビキチンリガーゼ / CUL4-DDB1 / PI3K / PIK3CA / Akt / トランスジェニックマウス … More / 肝癌 / 脂肪性肝炎 / 変異解析 / B型肝炎ウイルス / 自然免疫 / DNAセンサー / エピジェネティクス / cccDNA / ヒストンアセチル化 / HBV再活性化 / 再活性化 / Xタンパク / ユビキチン化 … More
Except Principal Investigator
肝細胞癌 / ゲノム / ゲノム異常 / Sharpin / 癌関連遺伝子 / バイオマーカー / 癌 / 遺伝子 / 炎症 / プロテオミクス / 臨床 / プロオミクス / 生体マーカー / 肝癌 / マイクロアレイ / ダノム / SNP / 胃癌 / 高密度オリゴヌクレオチドアレイ / 癌遺伝子 / 癌抑制遺伝子 / 肝臓 / 浸潤能 / ユビキチン / 直鎖型ポリユビキチン鎖 / SHARPIN / 細胞外マトリックス / 浸潤 / 転移 / Versican / 細胞外マトリックスプロテオグリカン / 糖タンパク質 / 個別化医療 / 血中循環腫瘍DNA Less
  • Research Projects

    (11 results)
  • Research Products

    (65 results)
  • Co-Researchers

    (33 People)
  •  B型肝炎ウイルス増殖抑制因子を標的とした新規治療法の開発Principal Investigator

    • Principal Investigator
      田中 康雄
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      The University of Tokyo
  •  血中循環腫瘍デオキシリボ核酸を用いた進行肝癌の個別化治療

    • Principal Investigator
      建石 良介
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      The University of Tokyo
  •  The role of ubiquitin-proteasome system in hepatitis B virus replicationPrincipal Investigator

    • Principal Investigator
      TANAKA YASUO
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      The University of Tokyo
  •  Targeting extracellular matrix proteoglycan Versican for diagnosis and therapy of hepatocellular carcinoma

    • Principal Investigator
      TATEISHI RYOSUKE
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      The University of Tokyo
  •  Elucidation of epigenetic regulation of hepatitis B virus replication and its therapeutic applicationPrincipal Investigator

    • Principal Investigator
      TANAKA YASUO
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      The University of Tokyo
  •  Analysis of the roles of linear polyubiquitin chains and Sharpin in hepatocellular carcinoma

    • Principal Investigator
      Tateishi Ryosuke
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      The University of Tokyo
  •  Hepatitis B virus evades DNA sensor-mediated IFN signaling pathways through interacting with STINGPrincipal Investigator

    • Principal Investigator
      TANAKA YASUO
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Research Field
      Gastroenterology
    • Research Institution
      The University of Tokyo
  •  包括的ゲノム解析による胃癌の発生・進展機構の解明

    • Principal Investigator
      岡本 真
    • Project Period (FY)
      2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      The University of Tokyo
  •  肝発癌におけるホスファチジルイノシトール3ーキナーゼの役割の解明Principal Investigator

    • Principal Investigator
      田中 康雄
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Gastroenterology
    • Research Institution
      The University of Tokyo
  •  Comprehensive analysis of allelic imbalance by using high-densitysingle nucleotide polymorphism array in hepatocellular carcinoma

    • Principal Investigator
      KANAI Fumihiko
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Chiba University
      The University of Tokyo
  •  Treatment of advanced liver cancer targeting tumor and tumor-related markers

    • Principal Investigator
      MAEDA Shin, 小俣 政男
    • Project Period (FY)
      2005 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo

All 2021 2020 2019 2018 2017 2016 2015 2013 2009 2008 2007 2006 2005 Other

All Journal Article Presentation

  • [Journal Article] Impact of Obesity and Heavy Alcohol Consumption on Hepatocellular Carcinoma Development after HCV Eradication with Antivirals2021

    • Author(s)
      Minami Tatsuya、Tateishi Ryosuke、Nakatsuka Takuma、Nakagawa Hayato、et al.
    • Journal Title

      Liver Cancer

      Volume: 10 Pages: 309-319

    • DOI

      10.1159/000513705

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K08352, KAKENHI-PROJECT-21K07906
  • [Journal Article] Inhibition of histone methyltransferase G9a attenuates liver cancer initiation by sensitizing DNA-damaged hepatocytes to p53-induced apoptosis2021

    • Author(s)
      Takuma Nakatsuka, Keisuke Tateishi*, Hiroyuki Kato, Hiroaki Fujiwara, Keisuke Yamamoto, Yotaro Kudo, Hayato Nakagawa, Yasuo Tanaka, Hideaki Ijichi, Tsuneo Ikenoue, Takeaki Ishizawa, Kiyoshi Hasegawa, Makoto Tachibana, Yoichi Shinkai, Kazuhiko Koike
    • Journal Title

      Cell Death & Disease

      Volume: 12 Pages: 99-111

    • DOI

      10.1038/s41419-020-03381-1

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H02419, KAKENHI-PROJECT-18K07961, KAKENHI-PROJECT-19K22388, KAKENHI-PROJECT-18K15741, KAKENHI-ORGANIZER-17H06423, KAKENHI-PLANNED-17H06424
  • [Journal Article] Cell fate analysis of zone 3 hepatocytes in liver injury and tumorigenesis2021

    • Author(s)
      Kurosaki Shigeyuki、Nakagawa Hayato、Hayata Yuki、Kawamura Satoshi、Matsushita Yuki、Yamada Tomoharu、Uchino Koji、Hayakawa Yoku、Suzuki Nobumi、Hata Masahiro、Tsuboi Mayo、Kinoshita Hiroto、Tanaka Yasuo、Nakatsuka Takuma、Hirata Yoshihiro、Tateishi Keisuke、Koike Kazuhiko
    • Journal Title

      JHEP Reports

      Volume: 3 Pages: 100315-100315

    • DOI

      10.1016/j.jhepr.2021.100315

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K07906, KAKENHI-PROJECT-21K19474
  • [Journal Article] Post-treatment cell-free DNA as a predictive biomarker in molecular-targeted therapy of hepatocellular carcinoma.2021

    • Author(s)
      Nakatsuka T、Nakagawa H、Hayata Y、Wake T、Yamada T、Nishibatake Kinoshita M、Nakagmi R、Sato M、Minami T、Uchino K、Enooku K、Kudo Y、Tanaka Y、Kishikawa T、Otsuka M、Tateishi R、Koike K
    • Journal Title

      J Gastroenterol.

      Volume: - Pages: 01773-4

    • DOI

      10.1007/s00535-021-01773-4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K08352, KAKENHI-PROJECT-18H02789, KAKENHI-PROJECT-18K07900, KAKENHI-PROJECT-21K07906
  • [Journal Article] Hepatocellular carcinoma development in diabetic patients: a nationwide survey in Japan.2021

    • Author(s)
      Tateishi R、Matsumura T、Okanoue T、Shima T、Uchino K、Fujiwara N、Senokuchi T、Kon K、Sasako T、Taniai M、Kawaguchi T、Inoue H、Watada H、Kubota N、Shimano H、Kaneko S、Hashimoto E、Watanabe S、Shiota G、Ueki K、Kashiwabara K、Matsuyama Y、Tanaka H、Kasuga M、Araki E、Koike K
    • Journal Title

      J Gastroenterol.

      Volume: 56 Pages: 261-273

    • DOI

      10.1007/s00535-020-01754-z

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K08352, KAKENHI-PROJECT-20K21611, KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-18H04051, KAKENHI-PROJECT-18K08482
  • [Journal Article] Improved liver function in patients with cirrhosis due to chronic hepatitis C virus who achieve sustained virologic response is not accompanied by increased liver volume2020

    • Author(s)
      Wake Taijiro、Tateishi Ryosuke、Fukumoto Tsuyoshi、Nakagomi Ryo、Kinoshita Mizuki Nishibatake、Nakatsuka Takuma、Sato Masaya、Minami Tatsuya、Uchino Koji、Enooku Kenichiro、Nakagawa Hayato、Fujinaga Hidetaka、Asaoka Yoshinari、Tanaka Yasuo、Otsuka Motoyuki、Koike Kazuhiko
    • Journal Title

      PLOS ONE

      Volume: 15

    • DOI

      10.1371/journal.pone.0231836

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K08352, KAKENHI-PROJECT-18K07961
  • [Journal Article] Soluble VCAM-1 promotes gemcitabine resistance via macrophage infiltration and predicts therapeutic response in pancreatic cancer2020

    • Author(s)
      Takahashi Ryota、Ijichi Hideaki、Sano Makoto、Miyabayashi Koji、Mohri Dai、Kim Jinsuk、Kimura Gen、Nakatsuka Takuma、Fujiwara Hiroaki、Yamamoto Keisuke、Kudo Yotaro、Tanaka Yasuo、Tateishi Keisuke、Nakai Yousuke、Morishita Yasuyuki、Soma Katsura、Takeda Norihiko、Moses Harold L.、Isayama Hiroyuki、Koike Kazuhiko
    • Journal Title

      Scientific Reports

      Volume: 10 Pages: 1-13

    • DOI

      10.1038/s41598-020-78320-3

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K07584, KAKENHI-PROJECT-20K08398, KAKENHI-PROJECT-18K07961, KAKENHI-PROJECT-18K07962, KAKENHI-PROJECT-18K15880
  • [Journal Article] Deletion of Histone Methyltransferase G9a Suppresses Mutant Kras-driven Pancreatic Carcinogenesis2020

    • Author(s)
      Hiroyuki Kato, Keisuke Tateishi*, Hiroaki Fujiwara, Hideaki Ijichi, Keisuke Yamamoto, Takuma Nakatsuka, Miwako Kakiuchi, Makoto Sano, Yotaro Kudo, Yoku Hayakawa, Hayato Nakagawa, Yasuo Tanaka, Motoyuki Otsuka, Yoshihiro Hirata, Makoto Tachibana, Yoichi Shinkai, Kazuhiko Koike
    • Journal Title

      Cancer Genomics - Proteomics

      Volume: 17 Pages: 695705-695705

    • DOI

      10.21873/cgp.20224

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H02419, KAKENHI-PROJECT-18K07961, KAKENHI-PROJECT-18K07962, KAKENHI-PROJECT-19K22388, KAKENHI-ORGANIZER-17H06423, KAKENHI-PLANNED-17H06424
  • [Journal Article] Mutant IDH1 confers resistance to energy stress in normal biliary cells through PFKP-induced aerobic glycolysis and AMPK activation.2019

    • Author(s)
      Fujiwara H、Tateishi K、Misumi K、Hayashi A、Igarashi K、Kato H、Nakatsuka T、Suzuki N、Yamamoto K、Kudo Y、Hayakawa Y、Nakagawa 、Tanaka Y、Ijichi H、Kogure H、Nakai Y、Isayama H、Hasegawa K、Fukayama M、Soga T、Koike K
    • Journal Title

      Sci Rep.

      Volume: 9 Pages: 18859-18859

    • DOI

      10.1038/s41598-019-55211-w

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07961, KAKENHI-PROJECT-19K17391, KAKENHI-PROJECT-19K17478, KAKENHI-PROJECT-17K09454, KAKENHI-PROJECT-18K07899, KAKENHI-PROJECT-18K07900
  • [Journal Article] A Novel Non-invasive Method for Predicting Liver Fibrosis by Quantifying the Hepatic Vein Waveform2019

    • Author(s)
      Soroida Y, Nakatsuka T, Sato M, Nakagawa H, Tanaka M, Yamauchi N, Wake T, Nakagomi R, Kinoshita MN, Minami T, Uchino K, Enooku K, Asaoka Y, Tanaka Y, Endo M, Nakamura A, Kobayashi T, Kurihara M, Hikita H, Sato M, Gotoh H, Iwai T, Fukayama M, Ikeda H, Tateishi R, Yatomi Y, Koike K.
    • Journal Title

      Ultrasound in Medicine & Biology

      Volume: 45 Pages: 2363-2371

    • DOI

      10.1016/j.ultrasmedbio.2019.05.028

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K06982, KAKENHI-PROJECT-18K07961
  • [Journal Article] Ischemic complications after percutaneous radiofrequency ablation of liver tumors: Liver volume loss and recovery2019

    • Author(s)
      Wake T、Tateishi R、Nakagomi R、Fujiwara N、Kinoshita MN、Nakatsuka T、Sato M、Minami T、Uchino K、Enooku K、Nakagawa H、Asaoka Y、Tanaka Y、Shiina S、Koike K
    • Journal Title

      Hepatology Research

      Volume: 49 Pages: 453-461

    • DOI

      10.1111/hepr.13302

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K07961
  • [Journal Article] Blocking CXCLs-CXCR2 axis in tumor-stromal interactions contributes to survival in a mouse model of pancreatic ductal adenocarcinoma through reduced cell invasion/migration and a shift of immune-inflammatory microenvironment.2019

    • Author(s)
      Sano Makoto、Ijichi Hideaki、Takahashi Ryota、Miyabayashi Koji、Fujiwara Hiroaki、Yamada Tomoharu、Kato Hiroyuki、Nakatsuka Takuma、Tanaka Yasuo、Tateishi Keisuke、Morishita Yasuyuki、Moses Harold L.、Isayama Hiroyuki、Koike Kazuhiko
    • Journal Title

      Oncogenesis.

      Volume: 8 Pages: 8-8

    • DOI

      10.1038/s41389-018-0117-8

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K09390, KAKENHI-PROJECT-18K07961, KAKENHI-PROJECT-17K09454, KAKENHI-PROJECT-18K07962, KAKENHI-PROJECT-19K08435
  • [Journal Article] Successful treatment of chronic hepatitis C virus infection with crushed glecaprevir/pibrentasvir administered via a percutaneous endoscopic gastrostomy tube: case report and review of the literature.2019

    • Author(s)
      Tanaka Y、Tateishi R、Koike K
    • Journal Title

      Clinical Journal of Gastroenterology

      Volume: 12 Pages: 588-591

    • DOI

      10.1007/s12328-019-00997-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K07961
  • [Journal Article] Isocitrate dehydrogenase 1 mutation sensitizes intrahepatic cholangiocarcinoma to the BET inhibitor JQ1.2018

    • Author(s)
      Fujiwara Hiroaki、Tateishi Keisuke、Kato Hiroyuki、Nakatsuka Takuma、Yamamoto Keisuke、Tanaka Yasuo、Ijichi Hideaki、Takahara Naminatsu、Mizuno Suguru、Kogure Hirofumi、Matsubara Saburo、Nakai Yousuke、Koike Kazuhiko
    • Journal Title

      Cancer Sci.

      Volume: 109 Pages: 3602-3610

    • DOI

      10.1111/cas.13784

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K07899, KAKENHI-PROJECT-18K07961, KAKENHI-PROJECT-18K07962, KAKENHI-PROJECT-16K09342, KAKENHI-PROJECT-16K09390, KAKENHI-PROJECT-16K09391
  • [Journal Article] Proteoglycans Are Attractive Biomarkers and Therapeutic Targets in Hepatocellular Carcinoma2018

    • Author(s)
      Tanaka Y, Tateishi R, Koike K.
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 19 Pages: 3070-3070

    • DOI

      10.3390/ijms19103070

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07961, KAKENHI-PROJECT-16K09342
  • [Journal Article] CPT2 downregulation adapts HCC to lipid-rich environment and promotes carcinogenesis via acylcarnitine accumulation in obesity.2018

    • Author(s)
      Fujiwara Naoto、Nakagawa Hayato、Enooku Kenichiro、Otsuka Motoyuki、Tateishi Keisuke、Koike Kazuhiko
    • Journal Title

      Gut.

      Volume: 67 Pages: 1493-1504

    • DOI

      10.1136/gutjnl-2017-315193

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04807, KAKENHI-PROJECT-15K19313, KAKENHI-PROJECT-16K19075, KAKENHI-PROJECT-18K07961, KAKENHI-PROJECT-16K09342
  • [Journal Article] Emerging role of SHARPIN in hepatocellular carcinoma progression2017

    • Author(s)
      Tanaka Y, Tateishi R, Koike K
    • Journal Title

      Cancer Cell Microenviron.

      Volume: 4

    • DOI

      10.14800/ccm.1540

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K09342
  • [Journal Article] Sharpin promotes hepatocellular carcinoma progression via transactivation of Versican expression.2016

    • Author(s)
      Tanaka Y, Tateishi K, Nakatsuka T, Kudo Y, Takahashi R, Miyabayashi K, Yamamoto K, Asaoka Y, Ijichi H, Tateishi R, Shibahara J, Fukayama M, Ishizawa T, Hasegawa K, Kokudo N, Koike K.
    • Journal Title

      Oncogenesis

      Volume: 5

    • DOI

      10.1038/oncsis.2016.76

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26460985, KAKENHI-PROJECT-16K09342
  • [Journal Article] Stromal remodeling by the BET bromodomain inhibitor JQ1 suppresses the progression of human pancreatic cancer.2016

    • Author(s)
      Yamamoto K, Tateishi K, Kudo Y, Hoshikawa M, Tanaka M, Nakatsuka T, Fujiwara H, Miyabayashi K, Takahashi R, Tanaka Y, Ijichi H, Nakai Y,Isayama H, Morishita Y, Aoki T, Sakamoto Y, Hasegawa K, Kokudo N, Fukayama M, Koike K.
    • Journal Title

      Oncotarget.

      Volume: 7 Pages: 61469-61484

    • DOI

      10.18632/oncotarget.11129

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K09040, KAKENHI-PROJECT-26460985
  • [Journal Article] A potent therapeutics for gallbladder cancer by combinatorial inhibition of the MAPK and mTOR signaling networks.2016

    • Author(s)
      Mohri D, Ijichi H, Miyabayashi K, Takahashi R, Kudo Y, Sasaki T, Asaoka Y, Tanaka Y, Ikenoue T, Tateishi K, Tada M, Isayama H, Koike K.
    • Journal Title

      J Gastroenterol.

      Volume: 印刷中 Pages: 711-21

    • DOI

      10.1007/s00535-015-1145-1

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26461031, KAKENHI-PROJECT-26460985
  • [Journal Article] Sarcopenia, Intramuscular Fat Deposition, and Visceral Adiposity Independently Predict the Outcomes of Hepatocellular Carcinoma.2015

    • Author(s)
      Fujiwara N, Nakagawa H, Kudo Y, Tateishi R, Taguri M, Watadani T, Nakagomi R, Kondo M, Nakatsuka T, Minami T, Sato M, Uchino K, Enooku K, Kondo Y, Asaoka Y, Tanaka Y, Ohtomo K, Shiina S, Koike K
    • Journal Title

      J Hepatol.

      Volume: 62 Pages: 131-140

    • DOI

      10.1016/j.jhep.2015.02.031

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24390183, KAKENHI-PROJECT-26460985, KAKENHI-PROJECT-15H04806, KAKENHI-PROJECT-15H04807, KAKENHI-PROJECT-25460979
  • [Journal Article] Absence of the AKT1 pleckstrin homology domain mutation in Japanese gastrointestinal and liver cancer patients2008

    • Author(s)
      Li Y, Tanaka Y, Tada M, Hua R, Seto M, Asaoka Y, Ohta M, Kanai F, Yoshida H, Kawabe T, Sano T, Motojima T, Yokosuka O, Omata M.
    • Journal Title

      APMIS 116

      Pages: 931-933

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016016
  • [Journal Article] Gain of GRHL2 isassociated with early recurrence of hepatocellular carcinoma2008

    • Author(s)
      Tanaka Y et.al.
    • Journal Title

      Journal of Hepatology 49

      Pages: 746-757

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590717
  • [Journal Article] Hepatocyte-specific PIK3CA transgenic mice develop steatohepatitis and hepatocellular carcinomas2008

    • Author(s)
      Yotaro Kudo, Yasuo Tanaka, et. al.
    • Journal Title

      In submission (掲載確定)

    • Data Source
      KAKENHI-PROJECT-19790470
  • [Journal Article] Potential relevance of cytoplasmic viral sensors and related regulators involving innate immunity in antiviral response.2008

    • Author(s)
      Asahina Y, Izumi N, Hirayama I, Tanaka T, Sato M, Yasui Y, Komatsu N, Umeda N, Hosokawa T, Ueda K, Tsuchiya K, Nakanishi H, Itakura J, Kurosaki M, Enomoto N, Tasaka M, Sakamoto N, Miyake S.
    • Journal Title

      Gastroenterology 134

      Pages: 1396-1405

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016016
  • [Journal Article] Down-regulation of hedgehog-interacting protein through genetic and epigenetic alterations in human hepatocellular carcinoma2008

    • Author(s)
      Tada M, Kanai F, Tanaka Y, Tateishi K, Ohta M, Asaoka Y, Seto M, Muroyama R, Fukai K, Imazeki F, Kawabe T, Yokosuka O, Omata M.
    • Journal Title

      Clin Cancer Res 14

      Pages: 3768-3776

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016016
  • [Journal Article] The presence of steatosis and elevation of alanine aminotransferase levels are associated with fibrosis progression in chronic hepatitis C with non-response to interferon therapy2008

    • Author(s)
      Kurosaki M, Matsunaga K, Hirayama I, Tanaka T, Sato M, Komatsu N, Umeda N, Hosokawa T, Ueda K, Tsuchiya K, Nakanishi H, Itakura J, Asahina Y, Miyake S, Enomoto N, Izumi N.
    • Journal Title

      J Hepatol 48

      Pages: 736-742

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016016
  • [Journal Article] Absence of the AKT1 pleckstrin homology domain mutation in Japanese gastrnintestinal and liver cancer patients2008

    • Author(s)
      Yuqin Li, Yasuo Tanaka, et. al.
    • Journal Title

      APMIS (掲載確定)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790470
  • [Journal Article] Rapid detection of the hepatitis B virus YMDD mutant using TaqMan-minor groove binder probes2008

    • Author(s)
      Hua R, Tanaka Y, Fukai K, Tada M, Seto M, Asaoka Y, Ohta M, Goto T, Kanai F, Kato N, Yoshida H, Kawabe T, Yokosuka O, Omata M.
    • Journal Title

      Clin Chim Acta 395

      Pages: 151-154

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016016
  • [Journal Article] Gain of GRHL2 is associated with early recurrence of hepatocellular carcinoma2008

    • Author(s)
      Tanaka Y, et al.,
    • Journal Title

      Journal of Hepatology 49

      Pages: 746-757

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590717
  • [Journal Article] Absence of PIK3CA hotspot mutations in hepatocellular carcinoma in Japanese patients2006

    • Author(s)
      Tanaka Y, Kanai F, Tada M, Asaoka Y, Guleng B, Jazag A, Ohta M, Ikenoue T, Tateishi K, Obi S, Kawabe T, Yokosuka O, Omata M.
    • Journal Title

      Oncogene 25

      Pages: 2950-2952

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016016
  • [Journal Article] Nucleotide change of codon 38 in the X gene of hepatitis B virus genotype C is associated with an increased risk of hepatocellular carcinoma2006

    • Author(s)
      Muroyama R, Kato N, Yoshida H, Otsuka M, Moriyama M, Wang Y, Shao RX, Dharel N, Tanaka Y, Ohta M, Tateishi R, Shiina S, Tatsukawa M, Fukai K, Imazeki F, Yokosuka O, Shiratori Y, Omata M.
    • Journal Title

      J Hepatol 45

      Pages: 805-812

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016016
  • [Journal Article] The hepatitis B virus X protein enhances AP-1 activation through interaction with Jab12006

    • Author(s)
      Tanaka Y, Kanai F, Ichimura T, Tateishi K, Asaoka Y, Guleng B, Jazag A, Ohta M, Imamura J, Ikenoue T, Ijichi H, Kawabe T, Isobe T, Omata M.
    • Journal Title

      Oncogene 25

      Pages: 633-642

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016016
  • [Journal Article] Absence of PIK3CA hotspot mutations in hepatocellular carcinoma in Japanese patients.2006

    • Author(s)
      Tanaka Y
    • Journal Title

      Oncogene 25

      Pages: 2950-2952

    • Data Source
      KAKENHI-PROJECT-17016016
  • [Journal Article] TRAIL-induced cell death cooperates with IFN-gamma activation in the graft-versus-tumor effect against colon tumors2006

    • Author(s)
      Tateishi K, Ohta M, Guleng B, Kanai F, Tanaka Y, Asaoka Y, Jazag A, Imamura J, Imamura T, Ijichi H, Ikenoue T, Kawakami T, Fukushima Y, Washida M, Sata M, Miyagishi M, Taira K, Yoshida H, Kawabe T, Omata M.
    • Journal Title

      Int J Cancer 118

      Pages: 2237-2246

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016016
  • [Journal Article] The hepatitis B virus X protein enhances Ap-1 activation through interaction with Jab1.2006

    • Author(s)
      Tanaka Y
    • Journal Title

      Oncogene 25

      Pages: 633-642

    • Data Source
      KAKENHI-PROJECT-17016016
  • [Journal Article] Proteomic analysis of sera from hepatocellular carcinoma patients after radiofrequency ablation treatment2005

    • Author(s)
      Kawakami T, Hoshida Y, Kanai F, Tanaka Y, Tateishi K, Ikenoue T, Obi S, Sato S, Teratani T, Shiina S, Kawabe T, Suzuki T, Hatano N, Taniguchi H, Omata M.
    • Journal Title

      Proteomics 5

      Pages: 4287-4295

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016016
  • [Presentation] ユビキチンリガーゼCHIPのHBxの安定性に与える影響の検討2021

    • Author(s)
      田中康雄、小池和彦
    • Organizer
      第57回日本肝臓学会総会
    • Data Source
      KAKENHI-PROJECT-21K07906
  • [Presentation] Post-treatment cell-free DNA as a predictive biomarker in molecular-targeted therapy of hepatocellular carcinoma2021

    • Author(s)
      Takuma Nakatsuka, Hayato Nakagawa, Yuki Hayata, Taijiro Wake, Tomoharu Yamada, Ryo Nakagomi, Masaya Sato, Tatsuya Minami, Koji Uchino, Kenichiro Enooku, Yotaro Kudo, Yasuo Tanaka, Motoyuki Otsuka, Ryosuke Tateishi, Kazuhiko Koike
    • Organizer
      JSH International Liver Conference 2021
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08352
  • [Presentation] Post-treatment cell-free DNA as a predictive biomarker in systemic therapy for HCC2021

    • Author(s)
      Takuma Nakatsuka, Hayato Nakagawa, Taijiro Wake, Tomoharu Yamada, Masaya Sato, Tatsuya Minami, Yotaro Kudo, Yasuo Tanaka, Motoyuki Otsuka, Ryosuke Tateishi, Kazuhiko Koike
    • Organizer
      APASL Oncology 2021
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08352
  • [Presentation] 治療後 cell-free DNA 解析による分子標的薬の治療効果予測2020

    • Author(s)
      中塚拓馬、中川勇人、早田有希、和気泰次郎、山田友春、木下瑞希、中込良、 佐藤雅哉、南達也、榎奥健一郎、工藤洋太郎、田中康雄、 大塚基之、建石良介、小池和彦
    • Organizer
      第23回日本肝がん分子標的治療研究会
    • Data Source
      KAKENHI-PROJECT-18K07961
  • [Presentation] 治療後 cell-free DNA 解析による分子標的薬の治療効果予測2020

    • Author(s)
      中塚拓馬、中川勇人、早田有希、和気泰次郎、山田友春、木下瑞希、中込良、 佐藤雅哉、南達也、榎奥健一郎、工藤洋太郎、田中康雄、大塚基之、建石良介、小池和彦
    • Organizer
      第23回日本肝がん分子標的治療研究会
    • Data Source
      KAKENHI-PROJECT-20K08352
  • [Presentation] 肝癌前駆細胞を制御するヒストンメチル化修飾機構2018

    • Author(s)
      中塚拓馬,立石敬介,工藤洋太郎,山本恵介,中川勇人,藤原弘明,田中康雄,酒井寿郎,油谷浩幸,眞貝洋一,小池和彦.
    • Organizer
      第55 回日本臨床分子医学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K07961
  • [Presentation] 肝癌前駆細胞を制御するヒストンメチル化修飾機構2018

    • Author(s)
      中塚拓馬,立石敬介,工藤洋太郎,山本恵介,中川勇人,藤原弘明,田中康雄,酒井寿郎,油谷浩幸,眞貝洋一,小池和彦.
    • Organizer
      第25 回肝細胞研究会
    • Data Source
      KAKENHI-PROJECT-18K07961
  • [Presentation] ATP 依存性RNA ヘリカーゼDDX1 のHBV 複製における役割の検討2018

    • Author(s)
      田中康雄,立石敬介,小池和彦.
    • Organizer
      第104 回日本消化器病学会総会
    • Data Source
      KAKENHI-PROJECT-18K07961
  • [Presentation] 新規癌関連遺伝子 Sharpin は細胞外マトリックスプロテオグリカン Versican の発現を介して肝癌進展に寄与する2017

    • Author(s)
      田中 康雄、立石敬介、建石良介、小池和彦
    • Organizer
      第54回日本臨床分子医学会学術集会
    • Data Source
      KAKENHI-PROJECT-16K09342
  • [Presentation] Sharpin cooperates with Wnt pathway to transactivate Versican expression to promote HCC invasion2016

    • Author(s)
      Yasuo Tanaka, Keisuke Tateishi, Takuma Nakatsuka , Yotaro Kudo, Yoshinari Asaoka, Ryosuke Tateishi, Kazuhiko Koike.
    • Organizer
      APASL(Asian Pacific Association for the Study of the Liver) 2016
    • Place of Presentation
      グランドプリンスホテル新高輪(東京都品川区)
    • Year and Date
      2016-02-20
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25460981
  • [Presentation] 新規がん遺伝子候補 Sharpinの 肝癌進展における役割の解明2015

    • Author(s)
      田中 康雄、立石 敬介、中塚 拓馬、宮林 弘至、高橋 良太、山本 恵介、工藤 洋太郎、浅岡 良成、伊地知 秀明、建石 良介、小池 和彦
    • Organizer
      日本消化器関連学会機構 JDDW 2015
    • Place of Presentation
      グランドプリンスホテル新高輪(東京都品川区)
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-25460981
  • [Presentation] グルココルチコイドによるエピジェネティクスを介したHBV複製制御メカニズムの解析2015

    • Author(s)
      田中康雄、立石敬介、中塚拓馬、工藤洋太郎、浅岡良成、堤武也、小池和彦
    • Organizer
      第51回日本肝臓学会総会
    • Place of Presentation
      ホテル日航熊本(熊本県・熊本市)
    • Year and Date
      2015-05-21
    • Data Source
      KAKENHI-PROJECT-26460985
  • [Presentation] 試験管内再構成系を用いたSTINGによるI型インターフェロン 誘導メカニズムの解析2013

    • Author(s)
      田中 康雄
    • Organizer
      第50回日本臨床分子医学会学術集会
    • Place of Presentation
      東京国際フォーラム
    • Data Source
      KAKENHI-PROJECT-24890042
  • [Presentation] Diagnosis of intrahepatic metastasis and multicentric carcinogenesis in the patients with hepatocellular carcinoma by Loss of heterozygosity analysis using taqman SNP genotyping assays2009

    • Author(s)
      Asaoka Y, Tanaka Y, Nakagawa H, Masuzaki R, Tada M, Tateishi R, Ijichi H, Ikenoue T, Maeda S, Yoshida H, Kawabe T, Omata M.
    • Organizer
      DDW
    • Place of Presentation
      Chicago
    • Year and Date
      2009-06-01
    • Data Source
      KAKENHI-PROJECT-17016016
  • [Presentation] Taqmanプローブを用いたLOH解析による再発肝癌のクロナリティーに関する検討2009

    • Author(s)
      浅岡良成、田中康雄、中川勇人、増崎亮太、多田素久、建石良介、伊地知秀明、池上恒雄、前田愼、吉田晴彦、小俣政男
    • Organizer
      JDDW 2009
    • Place of Presentation
      京都
    • Year and Date
      2009-10-15
    • Data Source
      KAKENHI-PROJECT-17016016
  • [Presentation] 高密度オリゴヌクレオチドアレイによる肝細胞癌の生物学的特性・再発に関連するゲノム異常解析2008

    • Author(s)
      田中康雄
    • Organizer
      日本肝臓学会
    • Place of Presentation
      愛媛県県民文化会館
    • Year and Date
      2008-06-05
    • Data Source
      KAKENHI-PROJECT-18590717
  • [Presentation] 高密度オリゴヌクレオチドアレイによる肝細胞癌の生物学的特性・再発に関連するゲノム異常解析2008

    • Author(s)
      田中康雄, ら
    • Organizer
      日本肝臓学会
    • Place of Presentation
      愛媛県県民会館
    • Year and Date
      2008-06-05
    • Data Source
      KAKENHI-PROJECT-18590717
  • [Presentation] 肝臓癌及び消化器癌の日本人患者におけるAKT1のpleckstrinホモロジードメイン変異の欠落2008

    • Author(s)
      Li Y、田中康雄、多田素久、華瑞、瀬戸元子、浅岡良成、大田幹、金井文彦、吉田晴彦、川邊隆夫、横須賀収、小俣政男
    • Organizer
      第44回日本肝臓学会総会
    • Place of Presentation
      愛媛
    • Year and Date
      2008-06-06
    • Data Source
      KAKENHI-PROJECT-17016016
  • [Presentation] Copy Number Analysis of Hepatocellular Carcinoma Using Ten Genes Derived from GeneChip Data Set of Hepatoma Cell Lines2007

    • Author(s)
      Tanaka Y, Kanai F, Tada M, Tateishi R, Shiina S, Kobashi H, Kawabe T, Yokosuka O, Ogawa S, Omata M
    • Organizer
      AASLD2007
    • Place of Presentation
      Boston, Massachusetts
    • Year and Date
      2007-11-03
    • Data Source
      KAKENHI-PROJECT-18590717
  • [Presentation] GeneChip Mapping 100K setから抽出した遺伝子を用いた肝癌臨床検体のコピー数解析2007

    • Author(s)
      田中康雄
    • Organizer
      第18回日本消化器癌発生学会総会
    • Place of Presentation
      ウエルシティ札幌
    • Year and Date
      2007-11-09
    • Data Source
      KAKENHI-PROJECT-17016016
  • [Presentation] 肝発癌によるHedgehog-interacting protein (HHIP)の関与2007

    • Author(s)
      多田素久、金井文彦、田中康雄、立石敬介、大田幹、浅岡良成、瀬戸元子、今関文夫、川邊隆夫、横須賀収、小俣政男
    • Organizer
      第43回日本肝癌研究会
    • Place of Presentation
      東京
    • Year and Date
      2007-06-01
    • Data Source
      KAKENHI-PROJECT-17016016
  • [Presentation] 高密度オリゴヌクレオチドアレイから抽出した遺伝子を用いた肝癌臨床検体のコピー数解析2007

    • Author(s)
      田中康雄、金井文彦、多田素久、建石良介、浅岡良成、瀬戸元子、大田幹、立石敬介、椎名秀一朗、吉田晴彦、川邊隆夫、横須賀収、小俣政男
    • Organizer
      JDDW
    • Place of Presentation
      神戸
    • Year and Date
      2007-10-19
    • Data Source
      KAKENHI-PROJECT-17016016
  • [Presentation] 高密度オリゴヌクレオチドアレイから抽出した遺伝子を用いた肝癌臨床検体のコピー数解析2007

    • Author(s)
      田中康雄
    • Organizer
      Japan Digestive Disease Week 2007
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2007-10-05
    • Data Source
      KAKENHI-PROJECT-17016016
  • [Presentation] グルココルチコイドによるエピジェネティクスを介したHBV複製制御メカニズムの解析

    • Author(s)
      田中 康雄、立石 敬介、中塚 拓馬、工藤 洋太郎、浅岡 良成、堤 武也、小池 和彦
    • Organizer
      第51回日本肝臓学会総会
    • Place of Presentation
      熊本
    • Year and Date
      2015-05-21 – 2015-05-22
    • Data Source
      KAKENHI-PROJECT-24890042
  • [Presentation] Hepatitis B virus transcription is enhanced with glucocorticoid through the acetylation of covalently closed circular DNA bound histones

    • Author(s)
      Yasuo Tanaka, Keisuke Tateishi, Takeya Tsutsumi, Kazuhiko Koike.
    • Organizer
      The 11th JSH Single Topic Conference
    • Place of Presentation
      Hiroshima, JAPAN
    • Year and Date
      2014-11-20 – 2014-11-21
    • Data Source
      KAKENHI-PROJECT-26460985
  • [Presentation] Sharpin promotes invasion of hepatocellular carcinoma through trans-activating Versican expressi

    • Author(s)
      Yasuo Tanaka, Keisuke Tateishi, Takuma Nakatsuka , Yotaro Kudo, Yoshinari Asaoka, Ryosuke Tateishi, Kazuhiko Koike
    • Organizer
      AASLD 2014 Annual Meeting
    • Place of Presentation
      Boston, USA
    • Year and Date
      2014-11-07 – 2014-11-11
    • Data Source
      KAKENHI-PROJECT-25460981
  • [Presentation] グルココルチコイドによるエピジェネティクスを介したHBV複製制御メカニズムの解 析

    • Author(s)
      田中 康雄、立石 敬介、中塚 拓馬、工藤 洋太郎、浅岡 良成、堤 武也、小池 和彦
    • Organizer
      第51回日本肝臓学会総会
    • Place of Presentation
      熊本
    • Year and Date
      2015-05-21 – 2015-05-22
    • Data Source
      KAKENHI-PROJECT-26460985
  • [Presentation] Hepatitis B virus transcription is enhanced with glucocorticoid through the acetylation of covalently closed circular DNA bound histones

    • Author(s)
      Yasuo Tanaka, Keisuke Tateishi, Takeya Tsutsumi, Kazuhiko Koike
    • Organizer
      11th JSH Single Topic Conference
    • Place of Presentation
      Hiroshima, JAPAN
    • Year and Date
      2014-11-20 – 2014-11-21
    • Data Source
      KAKENHI-PROJECT-24890042
  • 1.  Tateishi Ryosuke (50444089)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 30 results
  • 2.  KANAI Fumihiko (70334399)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 11 results
  • 3.  TATEISHI Keisuke (20396948)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 22 results
  • 4.  MAEDA Shin (40415956)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 5.  ENOMOTO Nobuyuki (20251530)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 6.  SASAKI Shigeru (10305229)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  小俣 政男 (90125914)
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    # of Collaborated Products: 13 results
  • 8.  吉田 晴彦 (60240305)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 8 results
  • 9.  岡本 真 (60334398)
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    # of Collaborated Products: 7 results
  • 11.  中塚 拓馬 (50772042)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 8 results
  • 12.  工藤 洋太郎 (90608358)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 13.  ASAOKA Yoshinari
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 14.  KONDO Yuuji
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 15.  FUJIWARA hiroaki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 4 results
  • 16.  IKENOUE Tsuneo
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 17.  鈴木 伸三
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    # of Collaborated Products: 1 results
  • 18.  木暮 宏史
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    # of Collaborated Products: 2 results
  • 19.  立花 誠
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    # of Collaborated Products: 2 results
  • 20.  田中 実
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    # of Collaborated Products: 2 results
  • 21.  伊地知 秀明
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  • 22.  山本 恵介
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 23.  小池 和彦
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 24.  田中 麻理子
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    # of Collaborated Products: 1 results
  • 25.  中井 陽介
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  • 26.  水野 卓
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  • 27.  松原 三郎
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  • 28.  早河 翼
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  • 29.  相馬 桂
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  • 30.  南 達也
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  • 31.  林 玲匡
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  • 32.  島野 仁
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  • 33.  荒木 栄一
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