SHIMADA Naohiko 嶋田直彦

… Alternative Names

嶋田直彦シマダナオヒコ

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Researcher Number	10423972
Other IDs
Affiliation (Current)	2025: 東京科学大学, 生命理工学院, 助教
Affiliation (based on the past Project Information) *help	2020 – 2024: 東京工業大学, 生命理工学院, 助教 2016 – 2018: 東京工業大学, 生命理工学院, 助教 2015: 東京工業大学, 大学院生命理工学研究科, 助教 2013 – 2015: 東京工業大学, 生命理工学研究科, 助教 2008 – 2012: Kyushu University, 先導物質化学研究所, 学術研究員 2011: 九州大学, 先導物質化学研究所, 特任助教
Review Section/Research Field	Principal Investigator Biomedical engineering/Biomaterial science and engineering / Science and Engineering / Chemistry related to living body / Basic Section 90120:Biomaterials-related Except Principal Investigator Transformative Research Areas, Section (IV) / Science and Engineering
Keywords	Principal Investigator UCST / カチオン性高分子 / 温度応答性高分子 / 分子ブースター / DNA鎖交換反応 / 高分子 / 液液相分離 / 相分離 / 酵素 / 細胞 … More / 光応答 / 光応答性 / ウレイド高分子 / UCST型高分子 / DNAロジックゲート / DNA論理ゲート / 生分解 / ポリペプチド / ペプチド / ウレイド基 / 分子ロボット / カチオン性共重合 / 生理的条件下 / CDスペクトル / カチオン性共重合体 / B-Z転移 / B-Z DNA転移 / 高分子構造・物性 / 核酸 / 生体関連高分子化学 … More Except Principal Investigator 可塑性 / 記憶と学習 / 分子コンピューティング / DNAコンピューティング / 両親媒性ペプチド / くし型共重合体 / DNA鎖交換 / DDS / 細胞内デリバリー / 核酸シャペロン / ハイブリダイゼーション / カチオン性くし型共重合体 / 遺伝子解析 / デオキシリボザイム / 薬物送達 / ベシクル-シート転移 / 生体膜 / リポソーム / カチオン性共重合体 / ターンオーバー / 酵素 / DNA / グラフト共重合体」 / 核酸検出 / 高分子電解質複合体 / グラフト共重合体 / 脂質膜 / ペプチド / 核酸酵素 / ＤＮＡ / カチオン性高分子 Less

液液相分離を惹起する酵素応答性ウレイド高分子の設計Principal Investigator
- Principal Investigator
  
  嶋田直彦
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 90120:Biomaterials-related
- Research Institution
  Tokyo Institute of Technology
Development of Molecular Memory / Molecular Learning Circuits for Minimal Artificial Brain
- Principal Investigator
  
  中茎隆
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (IV)
- Research Institution
  Kyushu Institute of Technology
Design of photo-responsive ureido polymersPrincipal Investigator
- Principal Investigator
  
  Shimada Naohiko
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  Tokyo Institute of Technology
超高速演算分子ブースターシステムの構築Principal Investigator
- Principal Investigator
  
  嶋田直彦
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Tokyo Institute of Technology
瞬速生体分子ロボットのための分子ブースター創製Principal Investigator
- Principal Investigator
  
  嶋田直彦
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Tokyo Institute of Technology
Design of polypeptide showing UCST-type phase transition behaviorPrincipal Investigator
- Principal Investigator
  
  Shimada Naohiko
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  Tokyo Institute of Technology
Evaluation of cellular functions by imaging cellular nucleic acids
- Principal Investigator
  
  Maruyama Atsushi
- Project Period (FY)
  2011 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Tokyo Institute of Technology
  Kyushu University
Development of DNA B-Z inducer as expression of cancer suppressor genePrincipal Investigator
- Principal Investigator
  
  SHIMADA Naohiko
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Chemistry related to living body
- Research Institution
  Kyushu University
Design of cationic molecule as a potential B-Z transition inducerPrincipal Investigator
- Principal Investigator
  
  SHIMADA Naohiko
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Chemistry related to living body
- Research Institution
  Kyushu University

[Book] 参画研究者紹介 "C01 分担者嶋田直彦"（学術変革領域（A) Molecular Cybernetics News Letter 分子サイバネティクスニュースレターVol.4）2021
- Author(s)
  嶋田直彦
- Total Pages
  52
- Publisher
  学術変革領域（A)「分子サイバネティクス」
- Data Source
  KAKENHI-PLANNED-20H05971
[Book] 刺激応答性高分子ハンドブック2018
- Author(s)
  嶋田直彦　丸山厚
- Total Pages
  864
- Publisher
  エヌ・ティーエス
- ISBN
- Data Source
  KAKENHI-PROJECT-16K01389
[Journal Article] Spontaneous Liquid Droplet-to-Gel Transition of Citrulline Polypeptide Complexed with Nucleic Acids2024
- Author(s)
  Nomura Shouhei、Miyasaka Ayano、Maruyama Atsushi、Shimada Naohiko
- Journal Title
  
  ACS Biomaterials Science & Engineering
  
  Volume: 10 Issue: 3 Pages: 1473-1480
- DOI
  10.1021/acsbiomaterials.3c01716
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K11846, KAKENHI-PLANNED-20H05971, KAKENHI-PROJECT-21H03816
[Journal Article] Malachite green-derivatized cationic comb-type copolymer acts as a photoresponsive artificial chaperone2023
- Author(s)
  Takemura Seiya、Shimada Naohiko、Maruyama Atsushi
- Journal Title
  
  Journal of Biomaterials Science, Polymer Edition
  
  Volume: 34 Issue: 18 Pages: 2463-2482
- DOI
  10.1080/09205063.2023.2265127
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-20H05971, KAKENHI-PROJECT-21H03816
[Journal Article] Encapsulation in cooling-induced coacervates augments DNA enzyme activity2023
- Author(s)
  Komachi Takuya、Kawai Shunya、Hirayama Yuki、Maruyama Atsushi、Shimada Naohiko
- Journal Title
  
  Polymer Chemistry
  
  Volume: 14 Issue: 41 Pages: 4743-4747
- DOI
  10.1039/d3py00923h
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K11846, KAKENHI-PLANNED-20H05971, KAKENHI-PROJECT-21H03816
[Journal Article] Cationic copolymer and crowding agent have a cooperative effect on a Na<sup>+</sup>-dependent DNAzyme2023
- Author(s)
  Wang Jun、Huang He、Hanpanich Orakan、Shimada Naohiko、Maruyama Atsushi
- Journal Title
  
  Biomaterials Science
  
  Volume: 11 Issue: 21 Pages: 7062-7066
- DOI
  10.1039/d3bm01119d
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-20H05971, KAKENHI-PROJECT-21H03816
[Journal Article] 2D?3D‐Convertible, pH‐Responsive Lipid Nanosheets2023
- Author(s)
  Zhang Wancheng、Takahashi Shutaro、Shimada Naohiko、Maruyama Atsushi
- Journal Title
  
  Small
  
  Volume: 19 Issue: 43 Pages: 2301219-2301219
- DOI
  10.1002/smll.202301219
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-20H05971, KAKENHI-PROJECT-21H03816
[Journal Article] Smart Protein Refolding System Based on UCST-Type Ureido Polymers2022
- Author(s)
  Tanaka Yamato、Niu Chun Hao、Sasaki Taira、Nomura Shouhei、Maruyama Atsushi、Shimada Naohiko
- Journal Title
  
  Biomacromolecules
  
  Volume: 23 Issue: 9 Pages: 3860-3865
- DOI
  10.1021/acs.biomac.2c00694
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20H05971, KAKENHI-PROJECT-21H03816
[Journal Article] Cationic Copolymer-Augmented DNA Hybridization Chain Reaction2022
- Author(s)
  Wang Jun、Shimada Naohiko、Maruyama Atsushi
- Journal Title
  
  ACS Applied Materials & Interfaces
  
  Volume: 14 Issue: 34 Pages: 39396-39403
- DOI
  10.1021/acsami.2c11548
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20H05971, KAKENHI-PROJECT-21H03816
[Journal Article] Simple and rapid RNA detection using cationic copolymer-chaperoned MNAzyme (ACEzyme)2021
- Author(s)
  YOSHIDA Naoki、HANPANICH Orakan、HAYASHI Raito、SHIMADA Naohiko、MARUYAMA Atsushi
- Journal Title
  
  Translational and Regulatory Sciences
  
  Volume: 3 Issue: 3 Pages: 102-105
- DOI
  10.33611/trs.2021-026
- NAID
  130008133945
- ISSN
  2434-4974
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H03816, KAKENHI-PLANNED-20H05971
[Journal Article] Light-Regulated Liquid?Liquid Phase Separation for Spatiotemporal Protein Recruitment and Cell Aggregation2021
- Author(s)
  Ikeuchi Nao、Komachi Takuya、Murayama Keiji、Asanuma Hiroyuki、Maruyama Atsushi、Shimada Naohiko
- Journal Title
  
  ACS Applied Materials & Interfaces
  
  Volume: 13 Issue: 4 Pages: 5652-5659
- DOI
  10.1021/acsami.0c22314
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K15399, KAKENHI-PLANNED-20H05971, KAKENHI-PROJECT-18H03933, KAKENHI-PLANNED-20H05970
[Journal Article] Rational Design of UCST-type Ureido Copolymers Based on a Hydrophobic Parameter2018
- Author(s)
  Shimada Naohiko、Sasaki Taira、Kawano Takakuni、Maruyama Atsushi
- Journal Title
  
  Biomacromolecules
  
  Volume: 19 Issue: 10 Pages: 4133-4138
- DOI
  10.1021/acs.biomac.8b01152
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H01807, KAKENHI-PROJECT-16K01389
[Journal Article] Highly Ordered Polypeptide with UCST Phase Separation Behavior2018
- Author(s)
  Kuroyanagi Sotaro、Shimada Naohiko、Fujii Shota、Furuta Tadaomi、Harada Atsushi、Sakurai Kazuo、Maruyama Atsushi
- Journal Title
  
  Journal of the American Chemical Society
  
  Volume: 141 Issue: 3 Pages: 1261-1268
- DOI
  10.1021/jacs.8b10168
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H01807, KAKENHI-PROJECT-16K01389
[Journal Article] Cooperative enhancement of deoxyribozyme activity by chemical modification and added cationic copolymer2016
- Author(s)
  Ken Saito, Naohiko Shimada, Atushi Maruyama
- Journal Title
  
  Science and Technology of Advanced Materials
  
  Volume: 17 Issue: 1 Pages: 437-442
- DOI
  10.1080/14686996.2016.1208627
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H00804, KAKENHI-WRAPUP-16H01692, KAKENHI-PROJECT-15H01807
[Journal Article] A reversible B-A transition of DNA duplexes induced by synthetic cationic copolymers†2016
- Author(s)
  Nonoka Yamaguchi, Yu-ki Zouzumi, Naohiko Shimada, Shu-ichi Nakano, Naoki Sugimoto, Atsushi Maruyama and Daisuke Miyoshi
- Journal Title
  
  Chem. Commun.,
  
  Volume: 52 Issue: 47 Pages: 7446-7449
- DOI
  10.1039/c6cc02237e
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-15H00804, KAKENHI-PROJECT-15H01807, KAKENHI-PROJECT-15H03840, KAKENHI-PROJECT-16K14042
[Journal Article] Preparation of upper critical solution temperature (UCST) responsive diblock copolymers bearing pendant ureido groups and their micelle formation behavior in water2016
- Author(s)
  A. Fujihara, N. Shimada, A. Maruyama, K. Ishihara, S. Yusa
- Journal Title
  
  Soft Matter
  
  Volume: - Issue: 26 Pages: 5204-5213
- DOI
  10.1039/c5sm00499c
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-23107007, KAKENHI-PROJECT-15J07540, KAKENHI-PROJECT-25350552, KAKENHI-PROJECT-25288101
[Journal Article] MNAzyme-catalysed nucleic acid detection enhanced by a cationic copolymer2015
- Author(s)
  J. Gao, N. Shimada, A. Maruyama
- Journal Title
  
  Biomater. Sci.
  
  Volume: 3 Issue: 5 Pages: 716-720
- DOI
  10.1039/c4bm00449c
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23240074, KAKENHI-PLANNED-23107007, KAKENHI-PROJECT-15H01807
[Journal Article] Inter-polyelectrolyte nano-assembly induces folding and activation of functional peptides2015
- Author(s)
  N. Shimada, H. Kinoshita, S, Tokunaga, T. Umegae, N. Kume, W. Sakamoto, A. Maruyama
- Journal Title
  
  J. Controlled Rel.
  
  Volume: 218 Pages: 45-52
- DOI
  10.1016/j.jconrel.2015.10.001
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-23107007, KAKENHI-PROJECT-15H01807
[Journal Article] DNA strand exchange reaction activated by cationic comb-type copolymers having ureido groups2014
- Author(s)
  Naohiko Shimada, Wei Song and Atsushi Maruyama
- Journal Title
  
  Biomater. Sci.
  
  Volume: 2 Issue: 10 Pages: 1480-1485
- DOI
  10.1039/c4bm00207e
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-25104520
[Journal Article] Smart hydrogels exhibiting UCST-type volume changes under physiologically relevant conditions2014
- Author(s)
  N. Shimada, S. Kidoaki, A. Maruyama
- Journal Title
  
  RSC Advances
  
  Volume: 4 Issue: 94 Pages: 1480-1485
- DOI
  10.1039/c4ra10612a
- NAID
  120006582365
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-23107007, KAKENHI-PROJECT-24300173, KAKENHI-PROJECT-25350552
[Journal Article] Lock-and-key mechanism for the controllable fabrication of DNA origami structures2014
- Author(s)
  R. Arivazhagan, M.Endo, K. Hidaka, N. Shimada, A. Maruyama, H. Sugiyama
- Journal Title
  
  Chem. Commun.
  
  Volume: 59 Issue: 63 Pages: 8743-8746
- DOI
  10.1039/c4cc02244k
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-23107007, KAKENHI-PROJECT-24310097, KAKENHI-PROJECT-26620133, KAKENHI-PLANNED-24104002
[Journal Article] Cationic comb-type copolymer excludes intercalating dye from DNA without inducing DNA condensation2014
- Author(s)
  A. Maruyama, N. Sonda, K. Yamasaki, S. Kidoaki, N. Shimada, M. Maeshiro, M. Miyazaki
- Journal Title
  
  Curr. Nanosci.
  
  Volume: 10 Issue: 2 Pages: 185-188
- DOI
  10.2174/1573413709666131129000024
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23107007
[Journal Article] Drastic stabilization of parallel DNA hybridizations by a polylysine omb-type copolymer with hydrophilic graft chain2014
- Author(s)
  D. Miyoshi, Y. M. Ueda, N. Shimada, S. I. Nakano, N. Sugimoto, A. Maruyama
- Journal Title
  
  ChemMedChem
  
  Volume: 9 Issue: 9 Pages: 2156-2163
- DOI
  10.1002/cmdc.201402157
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-23107007, KAKENHI-PROJECT-24245033, KAKENHI-PROJECT-24350089, KAKENHI-PUBLICLY-26107720
[Journal Article] Polycation-assisted DNA detection by reduction triggered fluorescence probe towards point-of-care testing2013
- Author(s)
  H. Saneyoshi, N. Yoshida, N. Shimada, A. Maruyama, Y. Ito, H. Abe
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 23 Issue: 24 Pages: 6851-6853
- DOI
  10.1016/j.bmcl.2013.10.005
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23107007, KAKENHI-PROJECT-24710266
[Journal Article] Polyelectrolyte-Assisted Transconformation of Stem-loop DNA2013
- Author(s)
  J. Du, L. Wu, N. Shimada, A. Kano, A. Maruyama
- Journal Title
  
  Chem. Commun.
  
  Volume: 49 Issue: 5 Pages: 475-477
- DOI
  10.1039/c2cc37139a
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23240074, KAKENHI-PLANNED-23107007
[Journal Article] Thermoresponsive Polymers with Functional Groups Selected for Pharmaceutical and Biomedical Applications2013
- Author(s)
  Naohiko Shimada, Atsushi Maruyama
- Journal Title
  
  ACS Symposium Series
  
  Volume: 1135 Pages: 235-241
- DOI
  10.1021/bk-2013-1135.ch014
- ISBN
  9780841227989, 9780841227996
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25350552
[Journal Article] Ureido-derivatized polymers based on both poly(allylurea) and poly(L-citrulline) exhibit UCST-type phase transition behavior under physiologically relevant conditions2011
- Author(s)
  Shimada, N.; Ino, H.; Maie, K.; Nakayama, M.; Kano, A.; Maruyama, A.
- Journal Title
  
  Biomacromolecules
  
  Volume: 12,(10) Issue: 10 Pages: 3418-22
- DOI
  10.1021/bm2010752
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22750157, KAKENHI-PLANNED-23107007
[Journal Article] Grafting of poly(ethylene glycol) to poly-lysine augments its lifetime in blood circulation and accumulation in tumors without loss of the ability to associate with siRNA2011
- Author(s)
  Kano, A.; Moriyama, K.; Yamano, T.; Nakamura, I.; Shimada, N.; Maruyama, A.
- Journal Title
  
  J Control Release
  
  Volume: 149,(1) Pages: 2-7
- NAID
  120004951559
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22750157
[Journal Article] DNA assembly and re-assembly activated by cationic comb-type copolymer2011
- Author(s)
  Moriyama, R.; Shimada, N.; Kano, A.; Maruyama, A.
- Journal Title
  
  Biomaterials
  
  Volume: 32,(9) Pages: 2351-2358
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22750157
[Journal Article] Cationic Graft Copolymer as a DNA B-Z Transition Inducer : Effect of Copolymer Structure2010
- Author(s)
  Shimada, N.; Yamamoto, M.; Kano, A.; Maruyama, A.
- Journal Title
  
  Biomacromolecules
  
  Volume: 11,(11) Issue: 11 Pages: 3043-3048
- DOI
  10.1021/bm100870b
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22750157
[Journal Article] Cationic Graft Copolymer as a DNA B-Z Transition Inducer : Effect of Copolymer Structure2010
- Author(s)
  N.Shimada, et al.
- Journal Title
  
  Biomacromolecules
  
  Volume: 11 Pages: 3043-3048
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22750157
[Journal Article] B-Z DNA Transition Triggered by a Cationic Comb-Type Copolymer2009
- Author(s)
  N. Shimada, A. Kano, A. Maruyama
- Journal Title
  
  Adv. Funct. Mater. 19
  
  Pages: 3590-3595
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20750140
[Journal Article] Design of cationic graft copolymers as a potential inducer of B-Z transition2009
- Author(s)
  N.Shimada, et al.
- Journal Title
  
  Nucleic Acids Symposium Series 53
  
  Pages: 251-252
- Data Source
  KAKENHI-PROJECT-20750140
[Journal Article] B-Z DNA Transition Triggered by a Cationic Comb-Type Copolymer2009
- Author(s)
  N.Shimada, et al.
- Journal Title
  
  Adv. Funct. Mater. 19
  
  Pages: 3590-3595
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20750140
[Journal Article] Design of cationic graft copolymers as a potential inducer of B-Z transition2009
- Author(s)
  N. Shimada, A. Kano, A. Maruyama
- Journal Title
  
  Nucleic Acids Symposium Series 53
  
  Pages: 251-252
- Data Source
  KAKENHI-PROJECT-20750140
[Journal Article] Effect of cationic comb-type copolymer on the B-Z transition of poly(dG-dC) poly(dG-dC)2008
- Author(s)
  N. Shimada, A. Kano, A. Maruyama
- Journal Title
  
  Nucleic Acids Symposium Series 52
  
  Pages: 113-114
- Data Source
  KAKENHI-PROJECT-20750140
[Journal Article] Effect of cationic comb-type copolymer on the B-Z transition of poly(dG-dC)-poly(dG-dC)2008
- Author(s)
  N. Shimada, et.al.
- Journal Title
  
  Nucleic Acids Symposium Series 52
  
  Pages: 113-114
- Data Source
  KAKENHI-PROJECT-20750140
[Patent] 温度応答性細胞塊作製方法2014
- Inventor(s)
  丸山厚、嶋田直彦
- Industrial Property Rights Holder
  丸山厚、嶋田直彦
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2014-228156
- Filing Date
  2014-11-10
- Data Source
  KAKENHI-PROJECT-25350552
[Patent] ポリ（２－メタクリロイルオキシエチルホスホリルコリン－ｂ－２－ウレイドエチルメタクリレート）共重合体及びそれにより形成される高分子ミセル2014
- Inventor(s)
  丸山厚、嶋田直彦、遊佐真一
- Industrial Property Rights Holder
  東京工業大学、兵庫県立大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2014-053966
- Filing Date
  2014-03-17
- Data Source
  KAKENHI-PROJECT-25350552
[Presentation] 光応答性高分子によるDNAコンピューティングの光スイッチ2023
- Author(s)
  平山裕基 , 嶋田直彦 , 丸山厚
- Organizer
  第73回高分子学会年次大会
- Data Source
  KAKENHI-PLANNED-20H05971
[Presentation] DNA-カチオン性くし型共重合体コンジュゲートの調製とDNA三重鎖形成能の評価2023
- Author(s)
  林来翔 , 斎藤美奈子 , 嶋田直彦 , 丸山厚
- Organizer
  第73回高分子学会年次大会
- Data Source
  KAKENHI-PLANNED-20H05971
[Presentation] ミニマル人工脳のための記憶・学習分子回路の開発2022
- Author(s)
  中茎隆，小宮健，川又生吹，嶋田直彦
- Organizer
  学術変革領域研究(A)「分子サイバネティクス」第２回領域会議
- Data Source
  KAKENHI-PLANNED-20H05971
[Presentation] 光応答性高分子によるDNA鎖置換反応の光スイッチ2022
- Author(s)
  平山裕基、嶋田直彦、丸山厚
- Organizer
  第71回高分子学会年次大会
- Data Source
  KAKENHI-PLANNED-20H05971
[Presentation] 分子ブースターによる DNA 鎖置換反応の加速効果の定量評価2022
- Author(s)
  川野隆宏，麻生かおり，嶋田直彦，丸山厚，中茎隆
- Organizer
  計測自動制御学会システム・情報部門学術講演会 2022 (SSI2022)
- Data Source
  KAKENHI-PLANNED-20H05971
[Presentation] Highly active DNAzyme nanowire cooperated with cationic copolymers2022
- Author(s)
  Naoki Yoshida, Jun Wang, Naohiko Shimada, Atsushi Maruyama
- Organizer
  第49回国際核酸化学シンポジウム
- Data Source
  KAKENHI-PLANNED-20H05971
[Presentation] 液相分離を示す温度応答性高分子と生体応用2022
- Author(s)
  嶋田直彦
- Organizer
  Future Trend in Polymer Science 2022
- Invited
- Data Source
  KAKENHI-PLANNED-20H05971
[Presentation] Preparation of Cationic Copolymer-Peptide Nucleic Acid Conjugates as DNA-responsive Chaperones2022
- Author(s)
  Wancheng ZHANG, Naohiko Shimada, Atsushi Maruyama
- Organizer
  第71回高分子討論会
- Data Source
  KAKENHI-PLANNED-20H05971
[Presentation] 光応答性ウレイド高分子による時空間的細胞形態制御とタンパク質リクルートメント2021
- Author(s)
  嶋田直彦 , 池内尚 , 小町卓也 , 村山恵司 , 浅沼浩之 , 丸山厚
- Organizer
  第70回高分子討論会
- Data Source
  KAKENHI-PLANNED-20H05971
[Presentation] Synthesis of cationic comb-type copolymer with photo-responsive molecule2021
- Author(s)
  Naoki Yoshida, Orakan Hanpanich, Naohiko Shimada, Atsushi Maruyama
- Organizer
  第70回高分子学会年次大会
- Data Source
  KAKENHI-PLANNED-20H05971
[Presentation] Synthesis of cationic comb-type copolymer with photo-responsive molecule2021
- Author(s)
  Seiya Takemura, Naohiko Shimada, Atsushi Maruyama
- Organizer
  第70回高分子学会年次大会
- Data Source
  KAKENHI-PLANNED-20H05971
[Presentation] ミニマル人工脳のための記憶・学習分子回路の開発2021
- Author(s)
  中茎隆，小宮健，川又生吹，嶋田直彦
- Organizer
  第1回分子サイバネティクス領域会議
- Data Source
  KAKENHI-PLANNED-20H05971
[Presentation] UCST型ウレイド高分子へのアゾベンゼン基導入による相転移の光制御2018
- Author(s)
  池内尚、嶋田直彦、村山恵司、浅沼浩之、丸山厚
- Organizer
  第67回高分子学会年次大会
- Data Source
  KAKENHI-PROJECT-16K01389
[Presentation] UCST型挙動を示すシトルリン共重合体の高次構造評価2018
- Author(s)
  畔柳奏太郎、嶋田直彦、藤井翔太、櫻井和朗、丸山厚
- Organizer
  第67回高分子学会年次大会
- Data Source
  KAKENHI-PROJECT-16K01389
[Presentation] アゾベンゼン基導入UCST型ウレイド高分子の相分離挙動の光制御2018
- Author(s)
  嶋田直彦, 池内尚, 村山恵司, 浅沼浩之, 丸山厚
- Organizer
  第40回バイオマテリアル学会大会
- Data Source
  KAKENHI-PROJECT-16K01389
[Presentation] アシル基導入ウレイド高分子のUCST 型挙動2018
- Author(s)
  嶋田直彦・佐々木泰・丸山厚
- Organizer
  第48回医用高分子シンポジウム
- Data Source
  KAKENHI-PROJECT-16K01389
[Presentation] UCST-Type Ureido Polymers as Biomaterials2018
- Author(s)
  Naohiko Shimada
- Organizer
  China-Japan Joint Symposium on Biomaterials 2018
- Invited
- Data Source
  KAKENHI-PROJECT-16K01389
[Presentation] アゾベンゼンを有するUCST型ウレイド高分子の設計と光応答性の評価2017
- Author(s)
  池内尚、嶋田直彦、丸山厚
- Organizer
  第66回高分子討論会
- Data Source
  KAKENHI-PROJECT-16K01389
[Presentation] 親疎水基を有するウレイド高分子のUCST挙動とバイオマテリアルへの応用2017
- Author(s)
  嶋田直彦・佐々木泰・丸山厚
- Organizer
  第66回高分子討論会
- Data Source
  KAKENHI-PROJECT-16K01389
[Presentation] アゾベンゼンを有するUCST型ウレイド高分子の合成と相転移の光制御評価2017
- Author(s)
  池内尚、嶋田直彦、丸山厚
- Organizer
  第39回日本バイオマテリアル学会大会
- Data Source
  KAKENHI-PROJECT-16K01389
[Presentation] 温度応答性ウレイド高分子による細胞培養形態制御2017
- Author(s)
  嶋田直彦　斉藤美奈子　丸山厚
- Organizer
  第46回医用高分子シンポジウム
- Data Source
  KAKENHI-PROJECT-16K01389
[Presentation] 尿素側鎖高分子の温度応答に親水性および疎水性が与える影響2017
- Author(s)
  佐々木泰、嶋田直彦、丸山厚
- Organizer
  第12回相模ケイ素・材料フォーラム
- Data Source
  KAKENHI-PROJECT-16K01389
[Presentation] カチオン性くし型共重合体によるDNA論理ゲートの高速化2016
- Author(s)
  齋藤健、嶋田直彦、丸山厚
- Organizer
  第65回高分子学会年次大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PUBLICLY-15H00804
[Presentation] カチオン性くし型共重合体による種々のDNAzyme活性の向上2016
- Author(s)
  齋藤健、嶋田直彦、丸山厚
- Organizer
  第65回高分子討論会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PUBLICLY-15H00804
[Presentation] UCST型温度応答性高分子を使った細胞培養形態スイッチング2016
- Author(s)
  嶋田直彦、齋藤美奈子、丸山厚
- Organizer
  日本バイオマテリアル学会シンポジウム 2016
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-16K01389
[Presentation] 疎水基導入によるウレイド高分子の合理的な感温性設計2016
- Author(s)
  佐々木泰、嶋田直彦、丸山厚
- Organizer
  第45回医用高分子シンポジウム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-16K01389
[Presentation] ウウレイドポリペプチドの二次構造がUCST型相転移挙動に与える影響2016
- Author(s)
  畔柳奏太郎、嶋田直彦、丸山厚
- Organizer
  第65回高分子討論会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-16K01389
[Presentation] UCST型挙動を示すポリペプチドの合成と評価2015
- Author(s)
  嶋田直彦，畔柳奏太郎，原田敦史，丸山厚
- Organizer
  第37回日本バイオマテリアル学会大会
- Place of Presentation
  京都テルサ
- Year and Date
  2015-11-09
- Data Source
  KAKENHI-PROJECT-25350552
[Presentation] 生理的バッファー中でUCST挙動を示すシトルリンポリペプチドの合成と評価2015
- Author(s)
  畔柳奏太郎、嶋田直彦、丸山厚
- Organizer
  第64回高分子討論会
- Place of Presentation
  東北大学
- Year and Date
  2015-09-16
- Data Source
  KAKENHI-PROJECT-25350552
[Presentation] Ureido-functionalized Polymers Exhibiting UCST-type Phase Separation Under Physiological Conditions2015
- Author(s)
  Naohiko Shimada, Minako Saito, Atsushi Maruyama
- Organizer
  2015 International Chemical Congress of Pacific Basin Societies
- Place of Presentation
  Hawai convention center
- Year and Date
  2015-12-15
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25350552
[Presentation] フローストレッチング法によるカチオン性共重合体とDNAの相互作用解析2015
- Author(s)
  高田朋繁、尊田尚孝、嶋田直彦、丸山厚
- Organizer
  第24回インテリジェント材料・システムシンポジウム
- Place of Presentation
  東京女子医大
- Year and Date
  2015-01-19
- Data Source
  KAKENHI-PUBLICLY-25104520
[Presentation] 感温性ウレイドポリペプチドの合成と評価2015
- Author(s)
  畔柳奏太郎、嶋田直彦、丸山厚
- Organizer
  第44回医用高分子シンポジウム
- Place of Presentation
  産業技術総合研究所臨海副都心センター別館11階会議室
- Year and Date
  2015-07-27
- Data Source
  KAKENHI-PROJECT-25350552
[Presentation] 新たな生命工学を拓く感温性高分子2015
- Author(s)
  嶋田直彦
- Organizer
  第65回医用高分子研究会
- Place of Presentation
  東京理科大学森戸記念館
- Year and Date
  2015-03-09
- Invited
- Data Source
  KAKENHI-PROJECT-25350552
[Presentation] DNA strand exchange reaction activated by cationic comb-type copolymers modified with ureido group2015
- Author(s)
  Naohiko Shimada, Song Wei, Atsushi Maruyama
- Organizer
  CBI学会
- Place of Presentation
  タワーホール船堀
- Year and Date
  2015-10-27
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H00804
[Presentation] バイオマテリアルとしてのUCST型ウレイド高分子の設計2013
- Author(s)
  嶋田直彦
- Organizer
  第35回日本バイオマテリアル学会
- Place of Presentation
  タワーホール船堀
- Data Source
  KAKENHI-PROJECT-25350552
[Presentation] 生体高分子の高次構造制御と温度応答性高分子2013
- Author(s)
  嶋田直彦
- Organizer
  バイオマテリアル若手研究会
- Place of Presentation
  八王子セミナーハウス
- Invited
- Data Source
  KAKENHI-PROJECT-25350552
[Presentation] 尿素基を有したカチオン性グラフト共重合体がDNA鎖交換反応に与える影響2013
- Author(s)
  嶋田直彦
- Organizer
  第62回高分子討論会
- Place of Presentation
  金沢大学
- Data Source
  KAKENHI-PUBLICLY-25104520
[Presentation] UREIDO-POLYMERS EXHIBITING UCST-TYPE PHASE SEPARATION BEHAVIOR UNDER PHYSIOLOGICALLY RELEVANT CONDITION2012
- Author(s)
  Shimada, N. et al
- Organizer
  43rd ACS National Meeting
- Place of Presentation
  Sandiego USA
- Year and Date
  2012-03-27
- Data Source
  KAKENHI-PROJECT-22750157
[Presentation] UREIDO-POLYMEES EXHIBITING UCST-TYPE PHASE SEPAEATION BEHAVIOR UNDER PHYSIOLOGICALLY RELEVANT CONDITION2012
- Author(s)
  N.Shimada, et al
- Organizer
  243rd ACS National Meeting
- Place of Presentation
  サンディエゴ、USA
- Year and Date
  2012-03-27
- Data Source
  KAKENHI-PROJECT-22750157
[Presentation] B-Z DNA transition induced by cationic comb-type copolymers2010
- Author(s)
  1. Shimada, N. et al
- Organizer
  Pacifichem 2010
- Place of Presentation
  Honolulu USA
- Year and Date
  2010-12-16
- Data Source
  KAKENHI-PROJECT-22750157
[Presentation] B-Z DNA transition induced by cationic comb-type copolymers2010
- Author(s)
  N.Shimada, et al.
- Organizer
  Pacifichem 2010
- Place of Presentation
  ホノルルコンベンショナルセンター(米国)
- Year and Date
  2010-12-16
- Data Source
  KAKENHI-PROJECT-22750157
[Presentation] DNAのB-Z転移に与えるカチオン性くし型共重合体の効果2009
- Author(s)
  嶋田直彦
- Organizer
  第19回バイオ・高分子シンポジウム
- Place of Presentation
  東京大学
- Year and Date
  2009-07-29
- Data Source
  KAKENHI-PROJECT-20750140
[Presentation] カチオン性くし型共重合体がDNAのB-Z転移に与える影響2009
- Author(s)
  嶋田直彦
- Organizer
  平成20年度九州支部有機材料研究会
- Place of Presentation
  九州工業大学
- Year and Date
  2009-02-28
- Data Source
  KAKENHI-PROJECT-20750140
[Presentation] カチオン性くし型共重合体による生体分子の二次構造制御2009
- Author(s)
  嶋田直彦
- Organizer
  大学間連携第5回物質合成シンポジウム
- Place of Presentation
  京都大学
- Year and Date
  2009-11-19
- Data Source
  KAKENHI-PROJECT-20750140
[Presentation] DNAのB-Z転移を誘起するカチオン性くし型共重合体の設計2009
- Author(s)
  嶋田直彦
- Organizer
  第58回高分子討論会
- Place of Presentation
  熊本大学
- Year and Date
  2009-09-16
- Data Source
  KAKENHI-PROJECT-20750140
[Presentation] DNAのB-Z転移に与えるカチオン性くし型共重合体の効果2008
- Author(s)
  嶋田直彦
- Organizer
  第57回高分子討論会
- Place of Presentation
  大阪府立大学
- Year and Date
  2008-09-24
- Data Source
  KAKENHI-PROJECT-20750140
[Presentation] ウレイド高分子が培養細胞に与える影響
- Author(s)
  嶋田直彦、斎藤美奈子、丸山厚
- Organizer
  第36回バイオマテリアル学会大会
- Place of Presentation
  タワーホール船堀
- Year and Date
  2014-11-17 – 2014-11-18
- Data Source
  KAKENHI-PROJECT-25350552
[Presentation] UCST型感温性高分子を利用したタンパク質の迅速かつ選択的な捕獲
- Author(s)
  河野貴国、嶋田直彦、丸山厚
- Organizer
  第36回バイオマテリアル学会大会
- Place of Presentation
  タワーホール船堀
- Year and Date
  2014-11-17 – 2014-11-18
- Data Source
  KAKENHI-PROJECT-25350552
[Presentation] ウレイド高分子からなるハイドロゲルの体積相転移
- Author(s)
  嶋田　直彦、三宅　大翔、斎藤　美奈子、丸山　厚
- Organizer
  第63回高分子討論会
- Place of Presentation
  長崎大学
- Year and Date
  2014-09-24 – 2014-09-26
- Data Source
  KAKENHI-PROJECT-25350552

1. Maruyama Atsushi (40190566)

# of Collaborated Projects: 3 results

# of Collaborated Products: 32 results
2. 狩野有宏 (30403950)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. 中茎隆 (30435664)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
4. 小宮健 (20396790)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. 川又生吹 (30733977)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. 村山恵司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

SHIMADA Naohiko 嶋田 直彦

嶋田 直彦 シマダ ナオヒコ

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液液相分離を惹起する酵素応答性ウレイド高分子の設計Principal Investigator

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Development of Molecular Memory / Molecular Learning Circuits for Minimal Artificial Brain

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Design of photo-responsive ureido polymersPrincipal Investigator

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超高速演算分子ブースターシステムの構築Principal Investigator

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瞬速生体分子ロボットのための分子ブースター創製Principal Investigator

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Design of polypeptide showing UCST-type phase transition behaviorPrincipal Investigator

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Evaluation of cellular functions by imaging cellular nucleic acids

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Development of DNA B-Z inducer as expression of cancer suppressor genePrincipal Investigator

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Design of cationic molecule as a potential B-Z transition inducerPrincipal Investigator

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[Book] 参画研究者紹介 "C01 分担者 嶋田直彦"（学術変革領域（A) Molecular Cybernetics News Letter 分子サイバネティクスニュースレターVol.4）2021

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[Book] 刺激応答性高分子ハンドブック2018

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[Journal Article] Spontaneous Liquid Droplet-to-Gel Transition of Citrulline Polypeptide Complexed with Nucleic Acids2024

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[Journal Article] Malachite green-derivatized cationic comb-type copolymer acts as a photoresponsive artificial chaperone2023

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SHIMADA Naohiko 嶋田直彦

嶋田直彦シマダナオヒコ

[Book] 参画研究者紹介 "C01 分担者嶋田直彦"（学術変革領域（A) Molecular Cybernetics News Letter 分子サイバネティクスニュースレターVol.4）2021