Yagi Hisashi 八木寿梓

… Alternative Names

YAGI Hisashi 八木寿梓

Less

Researcher Number	10432494
Other IDs
Affiliation (Current)	2025: 鳥取大学, 工学部, 准教授
Affiliation (based on the past Project Information) *help	2018 – 2024: 鳥取大学, 工学研究科, 准教授 2017: 鳥取大学, 工学研究科, 助教 2015 – 2016: 鳥取大学, 工学(系)研究科(研究院), 助教 2014: 鳥取大学, その他部局等, 助教 2014: 鳥取大学, 工学部, 助教 … More 2013: 鳥取大学, 工学(系)研究科(研究院), 助教 2010 – 2012: 大阪大学, 蛋白質研究所, 助教 2009: 阪大, たんぱく質研究所 2008: Osaka University, 蛋白質研究所, 特任研究員 Less
Review Section/Research Field	Principal Investigator Structural biochemistry / Living organism molecular science / Basic Section 59040:Nutrition science and health science-related Except Principal Investigator Basic Section 58060:Clinical nursing-related / Medium-sized Section 43:Biology at molecular to cellular levels, and related fields / Basic Section 38020:Applied microbiology-related / Neurology / Biophysics
Keywords	Principal Investigator アミロイド線維 / 蛋白質異常凝集検出装置 / 海藻 / リアルタイム観察 / 認知症 / 生活習慣病 / 海藻成分 / タンパク質異常凝集 / タンパク質 / 蛋白質異常凝集装置 … More / 多糖 / ヒトIselet amyloid polypeptide / ヒトIslet amyloid polypeptide / HFIP / アルコール / 全反射蛍光顕微鏡 / 活性酸素 / 損傷 / 増殖機構 / レーザー照射 / Amyloidβ(1-40) / 全反射蛍光顕微 … More Except Principal Investigator アミロイド線維 / αシヌクレイン / 凝集 / 蛋白質 / 酸素徐放剤 / 細菌感染 / 創傷被覆材 / 嫌気性菌 / がん性皮膚潰瘍 / 変性 / 脳神経変性疾患 / ポリリン酸 / 相転移 / 溶解度 / 過飽和 / 蛋白質凝集 / 老化 / 生体分子 / marine bacteria / polysaccharide / fucoidan / fucoidanase / アルギン酸 / アミロイド / 脱硫酸化酵素 / 海藻多糖分解酵素 / フコイダン / 多糖分解酵素 / 神経科学 / 神経内科学 / 構造解析 / J-PARC / SPring-8 / 生物物理学 / レビー小体 / パーキンソン病 / 神経変性疾患 / β2ミクログロブリン / アミロイドβペプチド / β２ミクログロブリン / 超音波 / フォールディング Less

海藻成分が線虫の寿命・認知に及ぼすインスリンシグナル伝達脳腸相関活性化機構解析Principal Investigator
- Principal Investigator
  
  八木寿梓
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Tottori University
がん性皮膚潰瘍の悪臭除去に有用な創傷被覆材の開発
- Principal Investigator
  
  古賀敦朗
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58060:Clinical nursing-related
- Research Institution
  Tottori University
Polyphosphate-dependent protein aggregation and its biological significance
- Principal Investigator
  
  Goto Yuji
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
- Research Institution
  Osaka University
Properties of novel microorganisms and enzymes involvedin marine polysaccharide degradation for utilizing marine biomass
- Principal Investigator
  
  Ohshiro Takashi
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38020:Applied microbiology-related
- Research Institution
  Tottori University
Identification of components and elucidation of molecular mechanisms of unused seaweeds for inhibition of protein aberrant aggregationPrincipal Investigator
- Principal Investigator
  
  YAGI Hisashi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  Tottori University
Screening and characterization of chemical compound derived from marine algae: Prevention of amyloid fibril formationPrincipal Investigator
- Principal Investigator
  
  Yagi Hisashi
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  Tottori University
Structure and function analysis of alpha-synuclein in Parkinson's disease
- Principal Investigator
  
  Mochizuki Hideki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  Osaka University
Role of supersaturation in the formation of amyloid fibrils
- Principal Investigator
  
  GOTO Yuji
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biophysics
- Research Institution
  Osaka University
Visualization of molecular mechanisms of amyloid fibril formationPrincipal Investigator
- Principal Investigator
  
  YAGI Hisashi
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Living organism molecular science
- Research Institution
  Osaka University
アミロイド線維超分子複合体形成機構と関連生体内因子の探索Principal Investigator
- Principal Investigator
  
  八木寿梓
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Living organism molecular science
- Research Institution
  Osaka University

[Journal Article] Occurrence of different fucoidanase genes in Flavobacterium sp. SW and enzyme characterization2022
- Author(s)
  Yoshihito Arai, Yunako Shingu, Hisashi Yagi, Hirokazu Suzuki, and Takashi Ohshiro
- Journal Title
  
  J. Biosci. Bioeng.
  
  Volume: 134 Issue: 3 Pages: 187-194
- DOI
  10.1016/j.jbiosc.2022.06.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K05392
[Journal Article] Limited spread of pathology within the brainstem of α-synuclein BAC transgenic mice inoculated with preformed fibrils into the gastrointestinal tract.2020
- Author(s)
  Uemura N, Yagi H, Uemura MT, Yamakado H, Takahashi R.
- Journal Title
  
  Neurosci Lett.
  
  Volume: 716 Pages: 134651-134651
- DOI
  10.1016/j.neulet.2019.134651
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K07308, KAKENHI-PROJECT-18H04041, KAKENHI-PROJECT-16K09672
[Journal Article] Inoculation of α-synuclein preformed fibrils into the mouse gastrointestinal tract induces Lewy body-like aggregates in the brainstem via the vagus nerve.2019
- Author(s)
  Uemura N, Yagi H, Uemura MT, Hatanaka Y, Yamakado H, Takahashi R.
- Journal Title
  
  Mol Neurodegener
  
  Volume: 14 Issue: 1 Pages: 31-31
- DOI
  10.1186/s13024-019-0331-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K07308
[Journal Article] Identification and characterization of the fucoidanase gene from Luteolibacter algae H182018
- Author(s)
  Nagao Tatsuhiko、Arai Yoshihito、Yamaoka Mika、Komatsu Fumika、Yagi Hisashi、Suzuki Hirokazu、Ohshiro Takashi
- Journal Title
  
  Journal of Bioscience and Bioengineering
  
  Volume: 126 Issue: 5 Pages: 567-572
- DOI
  10.1016/j.jbiosc.2018.05.016
- NAID
  40021726311
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K05392
[Journal Article] Microbial and genomic characterization of Geobacillus thermodenitrificans OS27, a marine thermophile that degrades diverse raw seaweeds2018
- Author(s)
  Fujii Kenta、Tominaga Yurie、Okunaka Jyumpei、Yagi Hisashi、Ohshiro Takashi、Suzuki Hirokazu
- Journal Title
  
  Applied Microbiology and Biotechnology
  
  Volume: 102 Issue: 11 Pages: 4901-4913
- DOI
  10.1007/s00253-018-8958-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K05392
[Journal Article] Characterization of a novel endo-type alginate lyase derived from Shewanella sp. YH12018
- Author(s)
  Yagi H, Fujise A, Itabashi N, Ohshiro T.
- Journal Title
  
  Journal of Biochemistry
  
  Volume: 163 Issue: 4 Pages: 341-350
- DOI
  10.1093/jb/mvy001
- NAID
  40021524088
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07308, KAKENHI-PROJECT-18K05392
[Journal Article] 未利用海藻から次世代機能性食品開発へ2017
- Author(s)
  八木寿梓
- Journal Title
  
  アグリバイオ
  
  Volume: 1(9) Pages: 80-83
- NAID
  40021807299
- Data Source
  KAKENHI-PROJECT-17K07308
[Journal Article] 未利用海藻を新たな資源として - 機能性食品・医薬品開発へ-2017
- Author(s)
  八木寿梓
- Journal Title
  
  アグリバイオ
  
  Volume: 1(4) Pages: 53-55
- NAID
  40021807211
- Data Source
  KAKENHI-PROJECT-17K07308
[Journal Article] Characterization of a Long-Lived Alginate Lyase Derived from Shewanella Species YH12017
- Author(s)
  Yagi H, Isobe N, Itabashi N, Fujise A, Ohshiro T.
- Journal Title
  
  Marine Drugs
  
  Volume: 16 Issue: 1 Pages: 4-4
- DOI
  10.3390/md16010004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07308, KAKENHI-PROJECT-18K05392
[Journal Article] Purification and characterization of a novel alginate lyase from the marine bacterium Cobetia sp. NAP1 isolated from brown algae.2016
- Author(s)
  Hisashi Yagi, Asako Fujise, Narumi Itabashi, Takashi Ohshiro
- Journal Title
  
  Biosci. Biotechnol. Biochem.
  
  Volume: 80 Issue: 12 Pages: 2338-2346
- DOI
  10.1080/09168451.2016.1232154
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K18490
[Journal Article] “Dynamical Behavior of Human α-Synuclein Studied by Quasielastic Neutron Scattering”2016
- Author(s)
  Satoru Fujiwara , Katsuya Araki, Tatsuhito Matsuo, Hisashi Yagi, Takeshi Yamada, Kaoru Shibata, Hideki Mochizuki
- Journal Title
  
  PLoS ONE
  
  Volume: 11 Issue: 4 Pages: e0151447-e0151447
- DOI
  10.1371/journal.pone.0151447
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25790005, KAKENHI-PUBLICLY-15H01558, KAKENHI-PROJECT-26293210, KAKENHI-PROJECT-16K13730
[Journal Article] A small-angle X-ray scattering study of alpha-synuclein from human red blood cells.2016
- Author(s)
  Araki K, Yagi N, Nakatani R, Sekiguchi H, So M, Yagi H, Ohta N, Nagai Y, Goto Y, Mochizuki H.
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Issue: 1 Pages: 30473-30473
- DOI
  10.1038/srep30473
- NAID
  120006557626
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01558, KAKENHI-ORGANIZER-26105001, KAKENHI-PROJECT-26293210, KAKENHI-PROJECT-16K09716, KAKENHI-INTERNATIONAL-15K21719, KAKENHI-PROJECT-16H05325
[Journal Article] Small Liposomes Accelerate the Fibrillation of Amyloid β2015
- Author(s)
  Mayu S. Terakawa, Hisashi Yagi, Masayuki Adachi, Young-Ho Lee, Yuji Goto
- Journal Title
  
  The Journal of Biological Chemistry
  
  Volume: 290 Issue: 2 Pages: 815-826
- DOI
  10.1074/jbc.m114.592527
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-13J03790, KAKENHI-PROJECT-24370067, KAKENHI-PROJECT-25870407
[Journal Article] Synchrotron FTIR Micro-Spectroscopy for Structural Analysis of Lewy Bodies in the Brain of Parkinson’s Disease Patients2015
- Author(s)
  K. Araki, N. Yagi, Y. Ikemoto, S. Choong, H. Hayakawa, G. Beck, H. Sumi, H. Fujimura, T. Moriwaki, Y. Nagai, Y. Goto and H. Mochizuki
- Journal Title
  
  Scientific Reports
  
  Volume: 5 Issue: 1 Pages: 17625-17625
- DOI
  10.1038/srep17625
- NAID
  120006557628
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K05142, KAKENHI-PUBLICLY-15H01558, KAKENHI-PROJECT-15H04362, KAKENHI-PROJECT-15K14339, KAKENHI-PROJECT-26670446, KAKENHI-PROJECT-26293210
[Journal Article] 超音波による蛋白質のアミロイド形成・結晶化の促進2014
- Author(s)
  宗正智、八木寿梓、後藤祐児
- Journal Title
  
  生物物理
  
  Volume: 6 Pages: 297-302
- NAID
  130004713028
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24370067
[Journal Article] Solubility and supersaturation-dependent protein misfolding revealed by ultrasonication.2014
- Author(s)
  Lin, Y., Lee, Y.-H., Yoshimura, Y., Yagi, Y. and Goto, Y.
- Journal Title
  
  Langmuir
  
  Volume: 30 Issue: 7 Pages: 1845-1854
- DOI
  10.1021/la403100h
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24370067, KAKENHI-PROJECT-25870407
[Journal Article] Supersaturation-limited Amyloid Fibrillation of Insulin Revealed by Ultrasonication2014
- Author(s)
  Hiroya Muta, Young-Ho Lee, Jozsef Kardos, Yuxi Lin, Hisashi Yagi, Yuji Goto
- Journal Title
  
  The Journal of Biological Chemistry
  
  Volume: 289 Issue: 26 Pages: 18228-18238
- DOI
  10.1074/jbc.m114.566950
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-14J04433, KAKENHI-PROJECT-24370067, KAKENHI-PROJECT-25870407
[Journal Article] Elongation of amyloid fibrils through lateral binding of monomers revealed by total internal reflection fluorescence microscopy.2014
- Author(s)
  Yagi, H., Abe, Y., Takayanagi, N. and Goto, Y.
- Journal Title
  
  Biochim. Biophys. Acta
  
  Volume: 1844 Issue: 10 Pages: 1881-1888
- DOI
  10.1016/j.bbapap.2014.06.014
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24370067
[Journal Article] Cold denaturation of alpha-synuclein amyloid fibrils.2014
- Author(s)
  Ikenoue, T. , Lee, Y.-H. , Kardos, J., Sakai, M., Yagi, H., Kawata, Y. and Goto, Y.
- Journal Title
  
  Angew. Chem. Int. Ed.
  
  Volume: 53 Issue: 30 Pages: 7799-7804
- DOI
  10.1002/anie.201403815
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24370067, KAKENHI-PROJECT-25440027, KAKENHI-PROJECT-25870407
[Journal Article] Heat of supersaturation-limited amyloid burst directly monitored by isothermal titration calorimetry.2014
- Author(s)
  Ikenoue, T., Lee, Y.-H., Kardos, J., Yagi, H., Ikegami, T., Naiki, H. and Goto, Y.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA
  
  Volume: 111 Issue: 18 Pages: 6654-6659
- DOI
  10.1073/pnas.1322602111
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24370067, KAKENHI-PROJECT-25293094, KAKENHI-PROJECT-25870407
[Journal Article] High-throughput analysis of the ultrasonication-forced amyloid fibrillation reveals underlying mechanism of the large fluctuation in the lag time2014
- Author(s)
  Ayaka Umemoto, Hisashi Yagi, Masatomo So, and Yuji Goto
- Journal Title
  
  The Journal of Biological Chemistry
  
  Volume: 289 Issue: 39 Pages: 27290-27299
- DOI
  10.1074/jbc.m114.569814
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13J01079, KAKENHI-PROJECT-24370067
[Journal Article] Acceleration of the depolymerization of amyloid  fibrils by ultrasonication.2013
- Author(s)
  Yagi , H., Hasegawa , K., Yoshimura, Y. and Goto, Y.
- Journal Title
  
  Biochim. Biophys. Acta.
  
  Volume: 1834 Issue: 12 Pages: 2480-2485
- DOI
  10.1016/j.bbapap.2013.08.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24370067
[Journal Article] Ultrasonication : An Efficient Agitation for Accelerating the Supersaturation- Limited Amyloid Fibrillation of Proteins2013
- Author(s)
  Yuichi Yoshimura, Masatomo So, Hisashi Yagi, and Yuji Goto
- Journal Title
  
  Japanese Journal of Applied Physics
  
  Volume: 52 Issue: 7S Pages: 07HA01-07HA01
- DOI
  10.7567/jjap.52.07ha01
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13J01079, KAKENHI-PROJECT-24370067
[Journal Article] Benzalkonium chloride accelerates the formation of the amyloid fibrils of corneal dystrophy-associated peptides.2013
- Author(s)
  Kato, Y., Yagi, H., Kaji, Y., Oshika, T. and Goto, Y.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 288 Issue: 35 Pages: 25109-25118
- DOI
  10.1074/jbc.m113.477695
- NAID
  120006557640
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24370067, KAKENHI-PROJECT-24592618, KAKENHI-PROJECT-25293353
[Journal Article] Structure, folding dynamics and amyloidogenesis of Asp76Asn β2-microglobulin: roles of shear flow, hydrophobic surfaces and α crystallin.2013
- Author(s)
  Mangione PP, Esposito G, Relini A, Raimondi S, Porcari R, Giorgetti S, Corazza A, Fogolari F, Penco A, Goto Y, Lee YH, Yagi H, Cecconi C, Naqvi MM, Gillmore JD, Hawkins PN, Chiti F, Rolandi R, Taylor GW, Pepys MB, Stoppini M, Bellotti V.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 288 Issue: 43 Pages: 30917-30930
- DOI
  10.1074/jbc.m113.498857
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24370067, KAKENHI-PROJECT-25870407
[Journal Article] Polymorphism ofβ2-Microglobulin amyloid fibrils manifested by ultrasonication-enhanced fibril formation in trifluoroethanol2012
- Author(s)
  Eri Chatani、Hisashi Yagi、Hironobu Naiki and Yuji Goto
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: (in press)
- URL
  http://www.jbc.org/content/early/2012/05/07/jbc.M111.333310.long
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22810014
[Journal Article] 蛍光顕微鏡観察によるアミロイド線維形成の分子機構2011
- Author(s)
  八木寿梓、後藤祐児
- Journal Title
  
  タンパク質の異常凝集とその防御・修復機構に関する研究会報告(III)
  
  Pages: 1-5
- Data Source
  KAKENHI-PROJECT-22810014
[Patent] フコイダンを有効成分とした認知症予防飲食物及び予防剤2016
- Inventor(s)
  八木寿梓、川本仁志、三木康成、大城隆
- Industrial Property Rights Holder
  八木寿梓、川本仁志、三木康成、大城隆
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2016-109105
- Filing Date
  2016-05-31
- Data Source
  KAKENHI-PROJECT-15K18490
[Presentation] 2種のフコイダン資化性微生物が有するフコイダン低分子化酵素の特性解明2023
- Author(s)
  高橋陽太，荒井良仁，新宮由奈子，八木寿梓，鈴木宏和，大城　隆
- Organizer
  日本農芸化学会中四国支部第64回講演会
- Data Source
  KAKENHI-PROJECT-18K05392
[Presentation] 海洋性細菌が持つ様々な海藻多糖に対する分解能検討2022
- Author(s)
  荒井良仁，新宮由奈子，八木寿梓，鈴木宏和，大城　隆
- Organizer
  日本農芸化学会2022年度中四国支部大会
- Data Source
  KAKENHI-PROJECT-18K05392
[Presentation] Flavobacterium sp. SW由来の特性の異なる2つのフコイダン低分子化酵素2022
- Author(s)
  新宮由奈子，荒井良仁，八木寿梓，鈴木宏和，大城　隆
- Organizer
  日本農芸化学会中四国支部第61回講演会
- Data Source
  KAKENHI-PROJECT-18K05392
[Presentation] アカモクフコイダン資化性菌の単離と特性解明2022
- Author(s)
  吉田優里，高橋陽太，荒井良仁，八木寿梓，鈴木宏和，大城　隆
- Organizer
  日本農芸化学会2022年度中四国支部大会
- Data Source
  KAKENHI-PROJECT-18K05392
[Presentation] Luteolibacter algae H18フコイダン低分子化酵素遺伝子の探索と異種発現2022
- Author(s)
  高橋陽太，荒井良仁，八木寿梓，鈴木宏和，大城　隆
- Organizer
  日本農芸化学会2022年度中四国支部大会
- Data Source
  KAKENHI-PROJECT-18K05392
[Presentation] Luteolibacter algae H18フコイダンスルファターゼの酵素化学的性質の解明2021
- Author(s)
  荒井良仁，倉本弥栄, 八木寿梓, 鈴木宏和, 大城隆
- Organizer
  日本農芸化学会２０２１年中四国支部大会
- Data Source
  KAKENHI-PROJECT-18K05392
[Presentation] PhoDファミリーに属するフコイダン脱硫酸化酵素の発見と分析2021
- Author(s)
  倉本弥栄、荒井良仁、八木寿梓、鈴木宏和、大城隆
- Organizer
  日本農芸化学会中四国支部第58回講演会
- Data Source
  KAKENHI-PROJECT-18K05392
[Presentation] Luteolibacter algae SWフコイダン低分子化酵素遺伝子の高発現と酵素の特性2020
- Author(s)
  新宮由奈子、小谷健太、藤原卓人、八木寿梓、鈴木宏和、大城隆
- Organizer
  日本農芸化学会2020年度中四国支部大会
- Data Source
  KAKENHI-PROJECT-18K05392
[Presentation] Luteolibacter algae SW由来フコイダン低分子化酵素の酵素化学的性質の解明2020
- Author(s)
  新宮由奈子、八木寿梓、鈴木宏和、大城隆
- Organizer
  日本生物工学会西日本支部大会2020
- Data Source
  KAKENHI-PROJECT-18K05392
[Presentation] タンパク質異常凝集形成を阻害する未利用海藻の有用性2019
- Author(s)
  伊藤佑夏、橋本日和、大城　隆、八木寿梓
- Organizer
  日本農芸化学会2019年度西日本・中四国支部合同大会
- Data Source
  KAKENHI-PROJECT-18K05392
[Presentation] Luteolibacter algae H18 由来フコイダン低分子化酵素によって生成するフコイダン分解産物の解析2019
- Author(s)
  荒井良仁、長尾達彦、八木寿梓、鈴木宏和、大城　隆
- Organizer
  日本農芸化学会2019年度大会
- Data Source
  KAKENHI-PROJECT-18K05392
[Presentation] 海藻アカモク抽出物によるアミロイド線維形成阻害効果と毒性評価2019
- Author(s)
  三輪明日香，矢崎幸拓，亀山春稀，三木康成，大城隆，八木寿梓
- Organizer
  日本農芸化学会西日本・中四国支部合同大会（第55回講演会）
- Data Source
  KAKENHI-PROJECT-17K07308
[Presentation] 海洋由来Luteolibacter algae H18 のフコイダン脱硫酸化酵素の精製とクローニング2019
- Author(s)
  倉本弥栄、小谷悠輔、山岡美花、長尾達彦、八木寿梓、鈴木宏和、大城　隆
- Organizer
  日本農芸化学会中四国支部第54回講演会
- Data Source
  KAKENHI-PROJECT-18K05392
[Presentation] 海洋由来Luteolibacter algae H18 のフコイダン脱硫酸化酵素の一次構造2019
- Author(s)
  倉本弥栄、小谷悠輔、山岡美花、八木寿梓、鈴木宏和、大城　隆
- Organizer
  日本農芸化学会2019年度西日本・中四国支部合同大会
- Data Source
  KAKENHI-PROJECT-18K05392
[Presentation] 海藻アカモク抽出物によるアミロイド線維形成阻害効果と毒性評価2019
- Author(s)
  三輪明日香、矢崎幸拓、亀山春稀、川本仁志、三木康成、大城　隆、八木寿梓
- Organizer
  日本農芸化学会2019年度西日本・中四国支部合同大会
- Data Source
  KAKENHI-PROJECT-18K05392
[Presentation] 「ゴミ・未利用」を「有用資源」へ─地域資源の魅力・再発見─2019
- Author(s)
  八木寿梓
- Organizer
  第8回超異分野学会
- Invited
- Data Source
  KAKENHI-PROJECT-17K07308
[Presentation] タンパク質異常凝集形成を阻害する未利用海藻の有用性2019
- Author(s)
  伊藤佑夏、橋本日和、大城隆、八木寿梓
- Organizer
  日本農芸化学会西日本・中四国支部合同大会（第55回講演会）
- Data Source
  KAKENHI-PROJECT-17K07308
[Presentation] 海洋由来Luteolibacter algae H18のフコイダン低分子化酵素：異種発現と諸性質検討2018
- Author(s)
  荒井良仁，長尾達彦，小松史佳，八木寿梓，鈴木宏和，大城隆
- Organizer
  2018年度日本農芸化学会大会
- Data Source
  KAKENHI-PROJECT-18K05392
[Presentation] 海藻成分を用いたアミロイド線維形成阻害2018
- Author(s)
  八木寿梓, 矢崎幸拓, 木下竣貴, 柏原直樹, 川本仁志, 三木康成, 大城隆
- Organizer
  第10回タンパク質の異常凝集とその防御・修復機構に関する研究会
- Invited
- Data Source
  KAKENHI-PROJECT-17K07308
[Presentation] フコイダン分解細菌Luteolibacter algae H18のスルファターゼについて2018
- Author(s)
  長尾達彦，小松史佳，八木寿梓，鈴木宏和，大城隆
- Organizer
  2018年度日本生物工学会西日本支部講演会
- Data Source
  KAKENHI-PROJECT-18K05392
[Presentation] 海洋由来Luteolibacter algae SW由来フコイダナーゼ遺伝子のクローニングと異種発現2018
- Author(s)
  荒井良仁，長尾達彦，小松史佳，八木寿梓，鈴木宏和，大城隆
- Organizer
  2018年度日本生物工学会大会
- Data Source
  KAKENHI-PROJECT-18K05392
[Presentation] 海藻多糖によるアミロイド線維形成阻害2018
- Author(s)
  矢崎幸拓, 木下竣貴, 柏原直樹, 川本仁志, 三木康成, 鈴木宏和, 大城隆, 八木寿梓
- Organizer
  第18回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-17K07308
[Presentation] 海藻分解性好熱菌に由来する新奇糖加水分解酵素の酵素学的研究2018
- Author(s)
  李原圭，藤井健太，八木寿梓，大城隆，鈴木宏和
- Organizer
  2018年度日本生物工学会西日本支部講演会
- Data Source
  KAKENHI-PROJECT-18K05392
[Presentation] 海藻多糖フコイダンによるアミロイド線維形成阻害2018
- Author(s)
  矢崎幸拓, 木下竣貴, 柏原直樹, 川本仁志, 三木康成, 大城隆, 八木寿梓
- Organizer
  生物工学会西日本支部講演会
- Data Source
  KAKENHI-PROJECT-17K07308
[Presentation] 未利用海藻を用いた次世代機能性食品開発に向けて2018
- Author(s)
  八木寿梓
- Organizer
  メディカルジャパン2018 関西広域連合　研究成果企業化促進セミナーアカデミックフォーラム
- Invited
- Data Source
  KAKENHI-PROJECT-17K07308
[Presentation] Gene identification and characterization of fucoidan deacetylase and fucoidanase for potential application to fucoidan degradation and diversification2018
- Author(s)
  Tatsuhiko Nagao, Yoshihito Arai, Fumika Komatsu, Ayako Kumabe, Mika Yamaoka, Hisashi Yagi, Hirokazu Suzuki, Takashi Ohshiro
- Organizer
  The 15th Japan-China-Korea Joint Symposium on Enzyme Engineering
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05392
[Presentation] 未利用海藻を新たな資源として2018
- Author(s)
  八木寿梓、大城隆
- Organizer
  第７回超異分野学会
- Data Source
  KAKENHI-PROJECT-17K07308
[Presentation] 海藻多糖によるアミロイド線維形成阻害2018
- Author(s)
  矢崎幸拓，木下竣貴，柏原直樹，川本仁志，三木康成，鈴木宏和，大城隆，八木寿梓
- Organizer
  第18回日本蛋白質科学会
- Data Source
  KAKENHI-PROJECT-18K05392
[Presentation] 海藻多糖フコイダンによるアミロイド線維形成阻害2018
- Author(s)
  矢崎幸拓，木下竣貴，柏原直樹，川本仁志，三木康成，大城隆，八木寿梓
- Organizer
  2018年度日本生物工学会西日本支部講演会
- Data Source
  KAKENHI-PROJECT-18K05392
[Presentation] 鳥取県の地域資源を活かしたマリンバイオロジーの展開2018
- Author(s)
  八木寿梓
- Organizer
  広島大学研究セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-17K07308
[Presentation] 鳥取の海から地域資源の発掘:「ゴミ・未利用物」を用いたマリンバイオロジーの展開2018
- Author(s)
  八木寿梓
- Organizer
  内外環境・代謝酵素研究会
- Invited
- Data Source
  KAKENHI-PROJECT-17K07308
[Presentation] フコイダン分解細菌Luteolibacter algae H18のフコシダーゼについて2018
- Author(s)
  長尾達彦，山岡美花，荒井良仁，八木寿梓，鈴木宏和，大城隆
- Organizer
  2018年度日本農芸化学会大会
- Data Source
  KAKENHI-PROJECT-18K05392
[Presentation] 「ゴミ・未利用」を「有用資源」へ ─地域創生を目指した海藻の底力─2017
- Author(s)
  八木寿梓
- Organizer
  第 1 回マリンテックグランプリ
- Data Source
  KAKENHI-PROJECT-17K07308
[Presentation] 海藻多糖によるアミロイド線維形成阻害2017
- Author(s)
  八木寿梓、木下竣貴、柏原直樹、川本仁志、三木康成、鈴木宏和、大城隆
- Organizer
  日本農芸化学会 2017年大会
- Place of Presentation
  京都女子大学
- Year and Date
  2017-03-19
- Data Source
  KAKENHI-PROJECT-15K18490
[Presentation] Shewanella sp. YH1 株が有するアルギン酸リアーゼの特性評価2017
- Author(s)
  八木寿梓、藤瀬麻紗子、板橋成美、礒部菜月、鈴木宏和、大城隆
- Organizer
  日本農芸化学会３支部合同大会
- Data Source
  KAKENHI-PROJECT-17K07308
[Presentation] Polysaccharide lyase family 7 に分類される Shewanella sp. YH1 株由来アルギン酸リアーゼの特性評価2016
- Author(s)
  八木寿梓、藤瀬麻紗子、板橋成美、鈴木宏和、大城隆
- Organizer
  日本農芸化学会中四国支部第 44 回講演会（例会）
- Place of Presentation
  岡山県立大学、岡山
- Year and Date
  2016-01-23
- Data Source
  KAKENHI-PROJECT-15K18490
[Presentation] Polysaccharide lyase 7 に分類される新規アルギン酸リアーゼの特性評価2016
- Author(s)
  八木寿梓、藤瀬麻紗子、板橋成美、鈴木宏和、大城隆
- Organizer
  日本農芸化学会2016
- Place of Presentation
  札幌コンベンションセンター、北海道
- Year and Date
  2016-03-29
- Data Source
  KAKENHI-PROJECT-15K18490
[Presentation] The structure analysis for alpha-synuclein and Lewy bodies with synchrotron radiation.2016
- Author(s)
  Katsuya Araki, Naoto Yagi, Rie Nakatani, Hideki Hayakawa, Kousuke Baba, Yuji Goto, Hideki Mochizuki.
- Organizer
  第57回日本神経学会学術大会
- Place of Presentation
  神戸コンベンションセンター
- Data Source
  KAKENHI-PROJECT-26293210
[Presentation] 放射光顕微赤外分光法を用いた剖検脳のグリア細胞内嗜銀性封入体の構造解析．2016
- Author(s)
  荒木克哉，八木直人，池中健介，早川英規，永井義隆，藤村晴俊，望月秀樹．
- Organizer
  第10回パーキンソン病・運動障害疾患コングレス
- Place of Presentation
  京都ホテルオークラ
- Data Source
  KAKENHI-PROJECT-26293210
[Presentation] The structure analysis for alpha-synuclein and Lewy bodies of Parkinson's disease patients with synchrotron radiation.2016
- Author(s)
  Katsuya Araki, Naoto Yagi, Rie Nakatani, Hideki Hayakawa, Kousuke Baba, Yuji Goto, Hideki Mochizuki.
- Organizer
  5th Asian and Oceanian Parkinson’s Disease and Movement Disorders Congress (AOPMC)
- Place of Presentation
  Manila, Philippines
- Year and Date
  2016-03-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293210
[Presentation] How should we understand the protein world2015
- Author(s)
  Hisashi Yagi
- Organizer
  NTU seminar
- Place of Presentation
  National Taiwan University , Taiwan
- Year and Date
  2015-11-26
- Invited
- Data Source
  KAKENHI-PROJECT-15K18490
[Presentation] Understanding the molecular mechanisms of amyloid fibrillation by using biophysical methods2015
- Author(s)
  Hisashi Yagi
- Organizer
  IBC seminar
- Place of Presentation
  Academia Sinica, Taiwan
- Year and Date
  2015-11-27
- Invited
- Data Source
  KAKENHI-PROJECT-15K18490
[Presentation] The structure analysis for alpha-synuclein and Lewy bodies with synchrotron radiation.2015
- Author(s)
  Katsuya Araki, Naoto Yagi, Rie Nakatani, Hideki Hayakawa, Kousuke Baba, Yuji Goto, Hideki Mochizuki.
- Organizer
  第56回　日本神経学会学術大会
- Place of Presentation
  新潟
- Year and Date
  2015-05-20
- Data Source
  KAKENHI-PROJECT-26293210
[Presentation] 全反射蛍光顕微鏡を用いたアミロイド線維形成反応の可視化2012
- Author(s)
  八木寿梓
- Organizer
  先端融合科学シンポジウムタンパク質アセンブリ-会合、超分子化、凝集-
- Place of Presentation
  神戸大学
- Data Source
  KAKENHI-PROJECT-22810014
[Presentation] 全反射蛍光顕微鏡を用いたアミロイド線維形成反応の可視化2012
- Author(s)
  八木寿梓
- Organizer
  先端融合科学シンポジウムタンパク質アセンブリ-会合、超分子化、凝集-
- Place of Presentation
  神戸大学(招待講演)
- Data Source
  KAKENHI-PROJECT-22810014
[Presentation] ケラトエピセリンペプチドのアミロイド線維形成に対する超音波と界面活性剤の効果2011
- Author(s)
  八木寿梓
- Organizer
  第4回タンパク質の異常凝集とその防御・修復機構に関する研究会
- Place of Presentation
  京都大学原子炉研究所
- Year and Date
  2011-11-11
- Data Source
  KAKENHI-PROJECT-22810014
[Presentation] The amyloid fibril growth of human islet amyloid polypeptide revealed by total internal reflection fluorescence microscopy2011
- Author(s)
  Hisashi Yagi
- Organizer
  The 3^<rd> Asia Pacific Protein Association Conference in conjunction with the 3^<rd> Symposium of the Chinese Protein Society
- Place of Presentation
  Shanghai, China
- Data Source
  KAKENHI-PROJECT-22810014
[Presentation] 超音波によるアミロイド線維形成2011
- Author(s)
  八木寿梓
- Organizer
  大阪大学蛋白質研究所セミナー
- Place of Presentation
  大阪大学蛋白質研究所
- Data Source
  KAKENHI-PROJECT-22810014
[Presentation] 天然変性蛋白質α-synucleinのアミロイド線維伸長直接観察2011
- Author(s)
  八木寿梓
- Organizer
  第11回日本蛋白質科学会年会
- Place of Presentation
  ホテル阪急エキスポパーク(大阪)(招待講演)
- Year and Date
  2011-06-08
- Data Source
  KAKENHI-PROJECT-22810014
[Presentation] 超音波によるアミロイド線維形成2011
- Author(s)
  八木寿梓
- Organizer
  大阪大学蛋白質研究所セミナー
- Place of Presentation
  大阪大学蛋白質研究所(招待講演)
- Data Source
  KAKENHI-PROJECT-22810014
[Presentation] ケラトエピセリンペプチドのアミロイド線維形成に対する超音波と界面活性剤の効果2011
- Author(s)
  八木寿梓
- Organizer
  第4回タンパク質の異常凝集とその防御・修復機構に関する研究会
- Place of Presentation
  京都大学原子炉研究所(招待講演)
- Year and Date
  2011-11-11
- Data Source
  KAKENHI-PROJECT-22810014
[Presentation] 天然変性蛋白質.-synucleinのアミロイド線維伸長直接観察2011
- Author(s)
  八木寿梓
- Organizer
  第11回日本蛋白質科学会年会
- Place of Presentation
  ホテル阪急エキスポパーク(大阪)
- Year and Date
  2011-06-08
- Data Source
  KAKENHI-PROJECT-22810014
[Presentation] 蛍光顕微鏡観察によるアミロイド線維形成の分子機構2010
- Author(s)
  八木寿梓
- Organizer
  第3回タンパク質の異常凝集とその防御・修復機構に関する研究会
- Place of Presentation
  京都大学原子炉研究所(招待講演)
- Year and Date
  2010-11-11
- Data Source
  KAKENHI-PROJECT-22810014
[Presentation] 蛍光顕微鏡観察によるアミロイド線維形成の分子機構2010
- Author(s)
  八木寿梓
- Organizer
  第3回タンパク質の異常凝集とその防御・修復機構に関する研究会
- Place of Presentation
  京都大学原子炉研究所
- Year and Date
  2010-11-11
- Data Source
  KAKENHI-PROJECT-22810014
[Presentation] 全反射蛍光顕微鏡によるα-synucleinのアミロイド線維伸長直接観察2008
- Author(s)
  八木寿梓
- Organizer
  BMB 2008
- Place of Presentation
  神戸, 兵庫, 日本
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-20710166
[Presentation] Real-time observation of the amyloid β (1-40) fibril propagation revealed by total internal reflection fluorescence microscopy2008
- Author(s)
  八木寿梓
- Organizer
  Protein Society
- Place of Presentation
  San Diego, CA, USA
- Year and Date
  2008-07-22
- Data Source
  KAKENHI-PROJECT-20710166

1. GOTO Yuji (40153770)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
2. SAKURAI Kazumasa (10403015)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. KAJI Yuichi (50361332)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. Mochizuki Hideki (90230044)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
5. Ohshiro Takashi (00233106)

# of Collaborated Projects: 1 results

# of Collaborated Products: 25 results
6. 藤原悟 (10354888)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 八木直人 (80133940)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
8. 荒木克哉 (50649431)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
9. 鈴木宏和 (80462696)

# of Collaborated Projects: 1 results

# of Collaborated Products: 22 results
10. 古賀敦朗 (90563891)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 伊福伸介 (70402980)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 大林徹也 (80348804)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 福原隆宏 (80403418)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 薮田行哲 (00379562)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 山田武

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 池本夕佳

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yagi Hisashi 八木 寿梓

YAGI Hisashi 八木 寿梓

Research Projects

Research Products

Co-Researchers

海藻成分が線虫の寿命・認知に及ぼすインスリンシグナル伝達脳腸相関活性化機構解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

がん性皮膚潰瘍の悪臭除去に有用な創傷被覆材の開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Polyphosphate-dependent protein aggregation and its biological significance

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Properties of novel microorganisms and enzymes involvedin marine polysaccharide degradation for utilizing marine biomass

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of components and elucidation of molecular mechanisms of unused seaweeds for inhibition of protein aberrant aggregationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Screening and characterization of chemical compound derived from marine algae: Prevention of amyloid fibril formationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Structure and function analysis of alpha-synuclein in Parkinson's disease

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Role of supersaturation in the formation of amyloid fibrils

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Visualization of molecular mechanisms of amyloid fibril formationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

アミロイド線維超分子複合体形成機構と関連生体内因子の探索Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Occurrence of different fucoidanase genes in Flavobacterium sp. SW and enzyme characterization2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Limited spread of pathology within the brainstem of α-synuclein BAC transgenic mice inoculated with preformed fibrils into the gastrointestinal tract.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Inoculation of α-synuclein preformed fibrils into the mouse gastrointestinal tract induces Lewy body-like aggregates in the brainstem via the vagus nerve.2019

Author(s)

Journal Title

DOI

Data Source

Yagi Hisashi 八木寿梓

YAGI Hisashi 八木寿梓