OOBAYASHI Tetsuya 大林徹也

… Alternative Names

Researcher Number	80348804
Other IDs
Affiliation (Current)	2020: 鳥取大学, 研究推進機構, 准教授
Affiliation (based on the past Project Information) *help	2018: 鳥取大学, 研究推進機構, 准教授 2013 – 2017: 鳥取大学, 生命機能研究支援センター, 准教授 2015: 鳥取大学, 生命機能研究支援センター動物資源開発分野, 分野長(准教授) 2011: 鳥取大学, 生命機能研究支援センタ, 准教授 2008 – 2010: Tottori University, 生命機能研究支援センター, 准教授 … More
Review Section/Research Field	Principal Investigator Life / Health / Medical informatics / Biological Sciences / Laboratory animal science Except Principal Investigator Applied genomics / Drug development chemistry / Pediatrics / Integrative animal science / General pharmacology / Kidney internal medicine / Pathological medical chemistry
Keywords	Principal Investigator 人工染色体ベクター / インテグレース / ゲノム編集 / 幹細胞 / ES細胞 / ヘテルクロマチン / リプログラミング / エピジェネティックス / 再生医療 / 遺伝子改変マウス … More Except Principal Investigator 人工染色体 / 人工染色体ベクター / ゲノムコピー数多型 / コピー数多型 / 抗体医薬 / 抗体医薬産生 / HOX遺伝子 / ヒスチジンリピート / 知的障害 / 遺伝子変異 / ニワトリ / 遺伝子改変 / トランスジェニックニワトリ / ゲノム編集 / ノックイン / ノックアウト / 始原生殖細胞 / 遺伝子組換え / オボムコイド / オボアルブミン / 遺伝子発現 / トランスポゾン / 微小核融合 / 腎毒性試験 / レポーター遺伝子 / 転写制御 / ヒト腎臓培養細胞株 / 培養細胞 / 腎毒性 / IL-6遺伝子レポーター / IL-8遺伝子レポーター / 尿酸 / 高尿酸血症 / 膜輸送 / トランスポーター / 創薬 / がん / SASP / 細胞老化 / 個体老化 / 炎症 / PITX1 / テロメレース / OIS / テロメア / ＰＩＴＸ１ / がん抑制遺伝子 / IL-6 / 炎症反応 / TERT / IL-8 Less

Rapid and easy detection of nephrotoxicity using human cultured cell lines; application of IL-6/IL-8 reporter gene
- Principal Investigator
  
  KOKURA Kenji
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Tottori University
A gene expression control system using a genome exchange technology on a mammalian artificial chromosome vectorPrincipal Investigator
- Principal Investigator
  
  Tetsuya Ohbayashi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Life / Health / Medical informatics
- Research Institution
  Tottori University
Elucidation of cellular senescence molecular mechanism through function analysis of tumor suppressor gene (PITX1) .
- Principal Investigator
  
  KUGOH Hiroyuki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Tottori University
Evaluation of 3-factor model (3F) of renal urate transport that may avoid less side-effect of druf-induced hyperuricemia.
- Principal Investigator
  
  Anzai Naohiko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Chiba University
  Dokkyo Medical University
A multiple gene expression switch using a multi-integrase system on a mammalian artificial chromosome vector.Principal Investigator
- Principal Investigator
  
  Ohbayashi Tetsuya
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Life / Health / Medical informatics
- Research Institution
  Tottori University
The world's first establishment of disease concept and mouse model creation about histidine repeat disease
- Principal Investigator
  
  NANBA EIJI
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Pediatrics
- Research Institution
  Tottori University
Methods for the establishment of genetically modified chicken which stably express foreign genes.
- Principal Investigator
  
  Oishi Isao
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Integrative animal science
- Research Institution
  National Institute of Advanced Industrial Science and Technology
Development of the antibody drug production system using a highly efficient artificial chromosome vector.
- Principal Investigator
  
  NISHIDA Tadashi
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Research Activity start-up
- Research Field
  
  Drug development chemistry
- Research Institution
  Tottori University
Generation of human artificial vector to allow the reproduction of gene copy number variation
- Principal Investigator
  
  INOUE Toshiaki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied genomics
- Research Institution
  Tottori University
The mechanism of developing age-dependent disease by loss of elasticity.Principal Investigator
- Principal Investigator
  
  OOBAYASHI Tetsuya
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Laboratory animal science
- Research Institution
  Tottori University
染体体構造を網羅的に検定する新技術による初期化に適したドナー細胞の同定Principal Investigator
- Principal Investigator
  
  大林徹也
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University

All 2018 2017 2016 2015 2014 2013 2012 2011 2009 2008 2007 Other

All Journal Article Presentation Patent

[Journal Article] Development of a multiple-gene-loading method by combining multi-integration system-equipped mouse artificial chromosome vector and CRISPR-Cas9.2018
- Author(s)
  Honma Kazuhisa、Abe Satoshi、Endo Takeshi、Uno Narumi、Oshimura Mitsuo、Ohbayashi Tetsuya、Kazuki Yasuhiro
- Journal Title
  
  PLoS One
  
  Volume: 13
- DOI
  10.1371/journal.pone.0193642
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25221308, KAKENHI-PROJECT-15K12141
[Journal Article] Multiple expression cassette exchange via TP901-1, R4, and Bxb1 integrase systems on a mouse artificial chromosome2017
- Author(s)
  Tomimatsu K, Kokura K, Nishida T, Yoshimura Y, Kazuki Y, Narita M, Oshimura M, Ohbayashi T.
- Journal Title
  
  FEBS Open Bio.
  
  Volume: 7 Pages: 306-317
- DOI
  10.1002/2211-5463.12169
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25221308, KAKENHI-PROJECT-16K08548, KAKENHI-PROJECT-15K12141
[Journal Article] A kidney injury molecule-1 (Kim-1) gene reporter in a mouse artificial chromosome: the responsiveness to cisplatin toxicity in immortalized mouse kidney S3 cells.2016
- Author(s)
  Kokura K, Kuromi Y, Endo T, Anzai N, Kazuki Y, Oshimura M, Ohbayashi T.
- Journal Title
  
  J Gene Med
  
  Volume: 18 Pages: 273-281
- DOI
  10.1002/jgm.2925
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25221308, KAKENHI-PROJECT-26461258, KAKENHI-PROJECT-16K08548
[Journal Article] Evaluation of an Hprt-Luciferase Reporter Gene on a Mammalian Artificial Chromosome in Response to Cytotoxicity.2016
- Author(s)
  Endo T, Noda N, Kuromi Y, Kokura K, Kazuki Y, Oshimura M, Ohbayashi T.
- Journal Title
  
  Yonago Acta Med.
  
  Volume: 59 Pages: 174-182
- NAID
  120005775326
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08548
[Journal Article] Human Artificial Chromosome for Delivering Trophic Factors in a Rodent Model of Amyotrophic Lateral Sclerosis2015
- Author(s)
  Watanabe Y, Kazuki Y, Kazuki K, Ebiki M, Nakanishi M, Nakamura K, Yoshida Yamakawa M, Hosokawa H, Ohbayashi T, Oshimura M, Nakashima K.
- Journal Title
  
  Mol Ther Nucleic Acids
  
  Volume: 4
- DOI
  10.1038/mtna.2015.28
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K12141, KAKENHI-PROJECT-25461315, KAKENHI-PROJECT-25540134
[Journal Article] Phenotype specific analyses reveal distinct regulatory mechanism for chronically activated p53.2015
- Author(s)
  Kirschner K, Samarajiwa SA, Cairns JM, Menon S, Pérez-Mancera PA, Tomimatsu K, Bermejo-Rodriguez C, Ito Y, Chandra T, Narita M, Lyons SK, Lynch AG, Kimura H, Ohbayashi T, Tavaré S, Narita M.
- Journal Title
  
  PLoS Genet
  
  Volume: 11
- DOI
  10.1371/journal.pgen.1005053
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-25116005, KAKENHI-PROJECT-15K12141
[Journal Article] Exploring the origin and limitations of kidney regeneration2015
- Author(s)
  Endo T, Nakamura J, Sato Y, Asada M, Yamada R, Takase M, Takaori K, Oguchi A, Iguchi T, Higashi AY, Ohbayashi T, Nakamura T, Muso E, Kimura T, Yanagita M.
- Journal Title
  
  Journal of Pathology
  
  Volume: 236(2) Pages: 251-263
- DOI
  10.1002/path.4514
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K12141, KAKENHI-PROJECT-25540134, KAKENHI-PROJECT-26670147, KAKENHI-PROJECT-26293202
[Journal Article] Phenotype specific analyses reveal distinct regulatory mechanism for chronically activated p53.2015
- Author(s)
  Kirschner K, Samarajiwa SA, Cairns JM, Menon S, Pérez-Mancera PA, Tomimatsu K, Bermejo-Rodriguez C, Ito Y, Chandra T, Narita M, Lyons SK, Lynch AG, Kimura H, Ohbayashi T, Tavaré S, Narita M.
- Journal Title
  
  PLoS Genet
  
  Volume: 11(3)
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25540134
[Journal Article] Exploring new gene integration sites for gene knock-in by gene-trapping strategy.2015
- Author(s)
  Nanchi I, Yoshimura Y, Nakamura K, Masago Y, Ohbayashi T, Okuda T.
- Journal Title
  
  Transgenic Res
  
  Volume: 24(3) Pages: 549-59
- DOI
  10.1007/s11248-015-9872-x
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K12141, KAKENHI-PROJECT-25540134
[Journal Article] Dual-color fluorescence imaging to monitor CYP3A4 and CYP3A7 expression in human hepatic carcinoma HepG2 and HepaRG cells.2014
- Author(s)
  Tsuji S, Kawamura F, Kubiura M, Hayashi A, Ohbayashi T, Kazuki Y, Chesné C, Oshimura M, Tada M.
- Journal Title
  
  PLoS One.
  
  Volume: 9(8)
- DOI
  10.1371/journal.pone.0104123
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25540134
[Journal Article] A novel and stable mouse artificial chromosome vector.2014
- Author(s)
  Takiguchi M, Kazuki Y, Hiramatsu K, Abe S, Iida Y, Takehara S, Nishida T, Ohbayashi T, Wakayama T, Oshimura M.
- Journal Title
  
  ACS Synth Biol
  
  Volume: 3(12) Pages: 903-14
- DOI
  10.1021/sb3000723
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25540134
[Journal Article] Fibulin-4 Conducts Proper Elastogenesis via Interaction with Cross-linking Enzyme Lysyl Oxidase2009
- Author(s)
  Horiguchi M, Inoue T, Ohbayashi T, Hirai M, Noda K, Marmorstein LY, Yabe D, Takagi K, Akama TO, Kita T, Kimura T, Nakamura T
- Journal Title
  
  Proc Natl Acad Sci U S A. 106
  
  Pages: 19029-19034
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20700365
[Journal Article] Fibulin-4 conducts proper elastogenesis via interaction with cross-linking enzyme lysyl oxidase2009
- Author(s)
  Horiguchi M, Inoue T, Ohbayashi T, Hirai M, Noda K, Marmorstein LY, Yabe D, Takagi K, Akama T O, Kita T, Kimura T, Nakamura T.
- Journal Title
  
  Proc Natl Acad Sci USA 106
  
  Pages: 19029-19034
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20700365
[Journal Article] Immunohistochemical investigation of mid-dermal elastolysis with a history of erythema.2008
- Author(s)
  Suda T, Hara H, Yoshitake M, Ohbayashi T,, Nakamura T, Terui T.
- Journal Title
  
  Am J Dermatopathol. 30(5)
  
  Pages: 477-80
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20700365
[Journal Article] Immunohistochemical investigation of mid-dermal elastolysis with a history of erythema2008
- Author(s)
  Suda T, Hara H, Yoshitake M, Ohbayashi T, Nakamura T, Terui T.
- Journal Title
  
  American Jurnal of Dermatopathol 30
  
  Pages: 477-480
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20700365
[Journal Article] Unscheduled overexpression of human WAPL promotes chromosomal instability2007
- Author(s)
  OHBAYASHI T.et al.
- Journal Title
  
  Biochemical and Biophysical Research Communications (in press)
- Data Source
  KAKENHI-PROJECT-17045015
[Patent] 人工染色体ベクター及び形質転換哺乳類細胞2013
- Inventor(s)
  中島芳浩、室冨和俊、安永茉由、大林徹也、押村光雄
- Industrial Property Rights Holder
  中島芳浩、室冨和俊、安永茉由、大林徹也、押村光雄
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2013-263910
- Filing Date
  2013-12-20
- Data Source
  KAKENHI-PROJECT-25540134
[Presentation] マウス・ヒト細胞株を用いた簡便なin vitro腎毒性応答の検出2018
- Author(s)
  古倉健嗣、井上敏昭、安西尚彦、大林徹也
- Organizer
  第59回日本生化学会　中国・四国支部例会
- Data Source
  KAKENHI-PROJECT-16K08548
[Presentation] 腎幹前駆細胞による再構成ネフロン様構造体を用いたin vitro 腎毒性試験法2018
- Author(s)
  大林徹也、古倉健嗣、喜多村真治
- Organizer
  第45回日本毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-16K08548
[Presentation] ゲノムプログラム&コントロールによる新しい遺伝子改変マウス2015
- Author(s)
  大林徹也
- Organizer
  第5回合成生物工学シンポジウム
- Place of Presentation
  神戸大学統合研究拠点コンベンションホール
- Year and Date
  2015-08-05
- Invited
- Data Source
  KAKENHI-PROJECT-25540134
[Presentation] ゲノムプログラム&コントロールによる新しい遺伝子改変マウス2015
- Author(s)
  大林徹也
- Organizer
  第5回合成生物工学シンポジウム
- Place of Presentation
  神戸大学統合研究拠点コンベンションホール
- Year and Date
  2015-08-05
- Invited
- Data Source
  KAKENHI-PROJECT-15K12141
[Presentation] 人工染色体ベクターを用いた好感度毒性評価の作成2012
- Author(s)
  西田直史、吉村裕貴、佐々木勝崇、中島芳浩、押村光雄、大林徹也
- Organizer
  第39回日本毒性学会学術年会
- Place of Presentation
  仙台国際センター(宮城)
- Data Source
  KAKENHI-PROJECT-22890114
[Presentation] APPLYING A HUMAN ARTIFICIAL CHROMOSOME VECTOR TO DE VELOP A HIGH-SENSITIVE BIOSENSOR CELL AS IN VITRO RISK ASSESSMENT METHOD2012
- Author(s)
  T. Nishida, Y. Yoshimura, Y. Nakajima, Y. Ohmiya, T. Ohbayashi, N. Tanaka and M. Oshimura
- Organizer
  2012Society of Toxicology Annual Meeting
- Place of Presentation
  Moscone convention center, San Francisco(USA)
- Year and Date
  2012-03-15
- Data Source
  KAKENHI-PROJECT-22890114
[Presentation] 任意の生命現象を制御できるバイオコントローラーとしての哺乳類人工染色体を搭載したモデル細胞をモデル動物の創出2011
- Author(s)
  大林徹也
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川)
- Year and Date
  2011-12-13
- Data Source
  KAKENHI-PROJECT-22890114
[Presentation] 人工染色体ベクターと多色・多様発光システムを融合した細胞アッセイシステムの開発2011
- Author(s)
  大林徹也
- Organizer
  日本実験動物代替法学会第24回大会
- Place of Presentation
  宮城県建設産業会館(宮城)
- Year and Date
  2011-11-11
- Data Source
  KAKENHI-PROJECT-22890114
[Presentation] Development of a high-sensitivity toxicity test system using chromosome engineering and bioluminescence technology2011
- Author(s)
  T. Nishida, Y. Yoshimura, K. Sasaki, Y. Nakajima, R. Saito, Y. Kazuki, S. Nishii, Y. Ohmiya, S. Aiba, M. Oshimura and T. Ohbayashi
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川)
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-22890114
[Presentation] 遺伝子改変動物を用いた弾性線維形成におけるDANCEプロセッシングの検討2009
- Author(s)
  堀口真仁, 大林徹也, 中邨智之
- Organizer
  第56回日本実験動物学会総会
- Place of Presentation
  大宮市
- Year and Date
  2009-05-14
- Data Source
  KAKENHI-PROJECT-20700365
[Presentation] DANCEは弾性線維形成のオーガナーザー因子であり、欠損したマウスは加齢進行性疾患の表現系を示す2009
- Author(s)
  大林徹也, 堀口真仁, 中邨智之
- Organizer
  第56回日本実験動物学会総会
- Place of Presentation
  大宮市
- Year and Date
  2009-05-14
- Data Source
  KAKENHI-PROJECT-20700365
[Presentation] 人工染色体を用いた蛍光・発光遺伝子導入マウス ES 細胞の樹立法
- Author(s)
  大林徹也、黒見靖、吉村祐貴、中村和臣、遠藤猛、中島芳、近江谷克裕、押村光雄
- Organizer
  日本実験動物代替法学会　第27回大会
- Place of Presentation
  横浜国立大学
- Year and Date
  2014-12-05 – 2014-12-07
- Data Source
  KAKENHI-PROJECT-25540134
[Presentation] 発光遺伝子によるマルチレポーターシステムの開発と創薬スクリーニングへの応用
- Author(s)
  大林徹也
- Organizer
  日本薬学会第134回年会
- Place of Presentation
  熊本　鶴屋ホール
- Invited
- Data Source
  KAKENHI-PROJECT-25540134
[Presentation] 発光・蛍光プローブ遺伝子を導入したマルチカラー細胞／マウスを迅速に作製するシステム
- Author(s)
  大林徹也
- Organizer
  光学イメージング２０１３
- Place of Presentation
  東京　秋葉原UDX Next1,2
- Data Source
  KAKENHI-PROJECT-25540134
[Presentation] 人工染色体ベクターによる遺伝子導入細胞を用いた in vitro 安全性試験法の有意性
- Author(s)
  押村光雄、中島芳浩、香月康宏、大林徹也
- Organizer
  日本実験動物代替法学会　第27回大会
- Place of Presentation
  横浜国立大学
- Year and Date
  2014-12-05 – 2014-12-07
- Data Source
  KAKENHI-PROJECT-25540134
[Presentation] 人工染色体ベクター導入発光マウス由来細胞を用いた毒性評価システム
- Author(s)
  大林徹也
- Organizer
  日本実験動物代替法学会第26回大会
- Place of Presentation
  京都　京都テレサ
- Invited
- Data Source
  KAKENHI-PROJECT-25540134
[Presentation] マルチインテグレースシステムの開発と染色体工学技術への応用
- Author(s)
  大林徹也
- Organizer
  鳥取大学染色体工学研究センター研究成果発表会
- Place of Presentation
  東京　ｷｬﾝﾊﾟｽ･ｲﾉﾍﾞｰｼｮﾝｾﾝﾀｰ東京
- Data Source
  KAKENHI-PROJECT-25540134
[Presentation] マルチインテグレースシステムを用いた遺伝子導入細胞・マウス作製技術
- Author(s)
  大林徹也
- Organizer
  第3回ゲノム編集研究会
- Place of Presentation
  広島　広島大学
- Data Source
  KAKENHI-PROJECT-25540134

1. NANBA Eiji (40237631)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. INOUE Toshiaki (80305573)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
3. Nakamura Kazuomi (90598137)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
4. KOKURA Kenji (30344039)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
5. KATOH Motonobu (00273904)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. TAKEYA Hiroyuki (60222105)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. NISHIDA Tadashi (50588556)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
8. OSHIMURA Mitsuo (20111619)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
9. KAZUKI Yasuhiro (90403401)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. HIGAKI Katsumi (90294321)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. ADACHI Kaori (50609237)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. Oishi Isao (50314472)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. TAGAMI Takahiro (60355104)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. Anzai Naohiko (70276054)

# of Collaborated Projects: 1 results

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15. SATO Motoyasu (20418891)

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# of Collaborated Products: 0 results
16. KUGOH Hiroyuki (40225131)

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17. 福村龍太郎 (90392240)

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18. JUTABHA Promsuk (90541748)

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19. 大内基司 (20409155)

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20. 大谷直由 (60711819)

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21. GOTO Yu-ichi

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22. HAYASHI Keitaro

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23. MORITA Asuka

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24. NOHARA Masakatsu

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25. WAKASHIN Hidefumi

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26. TSUCHIYA Go

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27. HORI Takayuki

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28. KANO Yuji

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29. ONIZAWA Nobuyuki

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30. OTSUKA Yusuke

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31. OHNO Yuta

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32. ENDOU Hitoshi

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33. KIMURA Toru

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34. TAMAI Ikumi

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35. OHIRA Takahito

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36. INAOKA Daigo

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37. Wempe Michael F.

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38. 渡邉保裕

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39. 木村宏

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40. 中邨智之

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41. 柳田素子

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# of Collaborated Products: 1 results

OOBAYASHI Tetsuya 大林 徹也

OHBAYASHI Tetsuya 大林 徹也

大林 徹也 オオバヤシ テツヤ

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Rapid and easy detection of nephrotoxicity using human cultured cell lines; application of IL-6/IL-8 reporter gene

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A gene expression control system using a genome exchange technology on a mammalian artificial chromosome vectorPrincipal Investigator

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Elucidation of cellular senescence molecular mechanism through function analysis of tumor suppressor gene (PITX1) .

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Evaluation of 3-factor model (3F) of renal urate transport that may avoid less side-effect of druf-induced hyperuricemia.

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A multiple gene expression switch using a multi-integrase system on a mammalian artificial chromosome vector.Principal Investigator

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The world's first establishment of disease concept and mouse model creation about histidine repeat disease

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Methods for the establishment of genetically modified chicken which stably express foreign genes.

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Development of the antibody drug production system using a highly efficient artificial chromosome vector.

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Generation of human artificial vector to allow the reproduction of gene copy number variation

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The mechanism of developing age-dependent disease by loss of elasticity.Principal Investigator

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染体体構造を網羅的に検定する新技術による初期化に適したドナー細胞の同定Principal Investigator

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[Journal Article] Development of a multiple-gene-loading method by combining multi-integration system-equipped mouse artificial chromosome vector and CRISPR-Cas9.2018

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[Journal Article] Multiple expression cassette exchange via TP901-1, R4, and Bxb1 integrase systems on a mouse artificial chromosome2017

Author(s)

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OOBAYASHI Tetsuya 大林徹也

OHBAYASHI Tetsuya 大林徹也

大林徹也オオバヤシテツヤ