TAKEYA Hiroyuki 武谷浩之

… Alternative Names

Researcher Number	60222105
Other IDs
External Links
Affiliation (Current)	2020: 崇城大学, 生物生命学部, 教授
Affiliation (based on the past Project Information) *help	2010 – 2014: 崇城大学, 生物生命学部, 教授 2007 – 2010: Tottori University, 医学部, 准教授 2006: 鳥取大学, 医学部, 助教授 2002 – 2003: School of Medicine, Lecturer, 医学部, 講師 2000 – 2001: 三重大学, 医学部, 講師 … More
Review Section/Research Field	Principal Investigator Structural biochemistry / Hematology / Hematology Except Principal Investigator Structural biochemistry / Laboratory medicine / Hematology / Pathological medical chemistry / Applied genomics / Circulatory organs internal medicine
Keywords	Principal Investigator 血液凝固 / アンチトロンビン / トロンビン / レセプター / セルピン / 炎症 / プロテアーゼ / 単球 / 血小板 / 細胞膜 … More Except Principal Investigator プロテインS / トロンボモジュリン / 血管内皮細胞 / プロテインC / プロテインC凝固制御系 / 組織因子 / 血栓症 / 先天性血栓性素因 / プロテインS欠損症 / アデノシン / アデノシン受容体 / トロンビン / EGF様ドメイン / 機能ドメイン / 分子間相互作用 / ELISA / プロテインCインヒビター / プロテインC受容体 / プロテインC欠損症 / APCレジスタンス / トロンボモジュリン欠損症 / プロテインC受容体欠損症 / 動脈硬化 / 血液凝固 / アデノシントランスポータ / NO産生酵素 / Gla-EGF1 / 血液凝固因子 / Factor VII / Factor IX / 血栓形成阻止 / EGFドメイン / 組換え蛋白質 / Protein S / 血液流動性維持機構 / protein C pathway / protein C / protein S / thrombomodulin / プロテインS受容体 / 活性化プロテインC / Protein S deficiency / 抗血栓性因子 / 細胞膜受容体 / protein C receptor / 炎症 / inflammation / 血液凝固制御系異常症 / プロテインC異常症 / プロテインS異常症 / 第V因子異常症 / 血液凝固制御 / NO / 内皮障害 / 内皮保護作用 / Scramblase / Amino-phospholipid translocase / 遺伝子治療 / 癌細胞 / アポトーシス / 細胞膜リン脂質二重層 / アデノウィルスベクター / アンチセンス法 / 細胞膜 / リン脂質 / ホスファチジルセリン / 癌 / カルシウム / 分子生物学 / ゲノムコピー数多型 / 人工染色体 / 人工染色体ベクター / コピー数多型 / VII因子 / 血液凝固反応 / Glaドメイン / VIIa因子 / IX因子 / VII-TF分子複合体 / Gla-EGF-1 / 外因系血液凝固反応 / 外因系凝固反応 / セレクチン / Tissue factor / Extrinsic blood coagulation / Gla-domain / Factor VIIa / VII-TF molecular complex / ホモシステイン / 遺伝子発現機構 / Anticoagulant protein C pathway / Thrombomodulin / Protein C / Factor X / Functional domain / EGF domain / 血管内皮傷害 / 傷害内皮分子マーカー / 可溶性トロンボモジュリン / 可溶性E-セレクチン / 活性化プロテインC-プロテインCインヒビター複合体 / 糖尿病 / 活性化プロテインC-プロテインCインヒビター複合体 / α_1アンチトリプシン / APC-PCI複合体 / APC-α_1-AT複合体 / 分子マーカー / 凝固亢進状態 / 血管内凝固 / Endothelium injury / Molecular marker for injured endothelim / Soluble thrombomodulin / Soluble E-selectin / Activated protein C-protein C inhibitor complex / Enzume-linked immunosorbent assay (ELISA) / Diabetes mellitus / Thrombotic disease / 血液凝固制御機構 / 先天性プロテインS異常症 / factor V / prothrombin / prothrombinase complex / molecular interaction / C4b結合蛋白質 / 抗凝固物質 / 抗炎症 / 肝類洞内皮細胞 / 抗血栓薬 / 抗炎症薬 / 肝障害動物実験モデル / 肝類洞内皮 / 活性評価法の開発 / C4b結合蛋白質(C4BP) / モノクローナル抗体 / Protein S receptor / C4b-binding protein / Activated protein C / Anticoagulants / Anti-inflammation / Sinusoid endothelial cells / プロテインC制御系 / 抗凝固系の異常症 / 遺伝子診断 / 人種別頻度差 / 人種 / Hereditary thrombophilia / Protein C deficiency / APC resistance / Thrombomodulin deficiency / Protein C receptor deficiency / Protein C pathway / Abnormality in the natural anticoagulant systems / 抗血栓性機構 / 血液流動性機構 / 遺伝子発現調節 / トロンボモジュリン異常症 / プロテインC受容体異常症 / protein C inibitor / blood fluidity mechanism / endothelial cells / protein S receptor / 臓器再生 / 臓器移植 / 再生分子マーカー / HGFアクチベーター / HGFA-PCI複合体 / ゲノミクス / DNAマイクロアレイ / 治療・診断法 / 肝細胞増殖因子 / 肝細胞増殖因子活性化因子 / プロテインチップ法 / SAGE法 / liver regeneration / protein C inhibitor / Hepatocyte growth factor activator / hepatocyte growth factor / activated protein C / protein chip-ELISA / molecular markers for tissue regeneration / 血管内皮 / 蛋白質構造・機能相関 / アスピリン / cGMP / cAMP / endothelium / anti-thrombotic property / protein structure-function relationship / aspirin / adenosine receptor / tissue factor / 障害血管 / RAF-AH / 酸化脂質 / アンギオポイエチン-1 / 遺伝子導入 / 骨髄由来前駆細胞 / 血小板活性化因子水解酵素(PAF-AH) / Angiopoietin-1 / 血栓 / 腫瘍血管新生 / 可溶型受容体 / 酸化LDL / 傷害 / 血管 / アデノウイルス / thrombosis / injured arteries / PAF-AH / oxidized lipoproteins / angiopoietin-1 / gene transfer / bone marrow-derived progenitor cell / 血液凝固IX因子 / 血友病B / 分子異常症 / 血液凝固VII因子 / エステル基質 / セリンプロテア-ゼ / IX因子Fukuoka / EGF-like domain / Oligosaccharide / Protein Z / Serine protease / cDNA cloning / gamma-Carboxyglutamic acid residue Less

Sphingolipid metabolism in thrombosis and hemostasisPrincipal Investigator
- Principal Investigator
  
  TAKEYA Hiroyuki
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Hematology
- Research Institution
  Sojo University
Human arterial chromosomes for new hemophilia therapyPrincipal Investigator
- Principal Investigator
  
  TAKETA Hiroyuki
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Hematology
- Research Institution
  Sojo University
  Tottori University
Generation of human artificial vector to allow the reproduction of gene copy number variation
- Principal Investigator
  
  INOUE Toshiaki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied genomics
- Research Institution
  Tottori University
組織因子による血管・リンパ管形成作用のオタマジャクシを用いた解析Principal Investigator
- Principal Investigator
  
  武谷浩之
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Hematology
- Research Institution
  Tottori University
Gene transfer-mediated molecular analysis of pathophysiology in injured arteries and development of local anti-inflammatory and anti-thrombotic therapy
- Principal Investigator
  
  UENO Hikaru
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  University of Occupational and Environmental Health
アポトーシス細胞のクリアランス機構を応用した新規な遺伝子治療法の開発研究
- Principal Investigator
  
  鈴木宏治
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Mie University
The structure and function of molecules which regulate the cell membrane phospholipid bi-layer.Principal Investigator
- Principal Investigator
  
  TAKEYA Hiroyuki
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  University of Occupational and Environmental Health
  Mie University
Development of high sensitive assay method to detect tissue specific regeneration markers -Protein chip -ELISA specific for liver regeneration
- Principal Investigator
  
  SUZUKI Koji
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Laboratory medicine
- Research Institution
  Mie University
Structure-function relationship of the endothelial cell membrane receptors playing in the anti-thrombotic properties.
- Principal Investigator
  
  SUZUKI Koji
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  Mie University
アデノシン受容体を介する血管内皮障害の保護機構に関する分子細胞生物学的研究
- Principal Investigator
  
  鈴木宏治
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Mie University
抗リン脂質抗体による血栓形成機序の分子病態学的解析Principal Investigator
- Principal Investigator
  
  武谷浩之
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Hematology
- Research Institution
  Mie University
アデノシンは血管内皮細胞の保護因子として機能するか?
- Principal Investigator
  
  鈴木宏治
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Hematology
- Research Institution
  Mie University
Molecular Genetic Studies on Protein C Pathway Abnormality
- Principal Investigator
  
  SUZUKI Koji
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Field
  
  Laboratory medicine
- Research Institution
  Mie University
Molecular biological studies on the blood fluidity - Structure-function relationship of the endothelial receptors playing in the anticoagulant protein C pathway
- Principal Investigator
  
  SUZUKI Koji
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  Mie University
トロンビンおよびアンチトロンビンIIIによる細胞機能変換の分子機構Principal Investigator
- Principal Investigator
  
  武谷浩之
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Structural biochemistry
- Research Institution
  Mie University
Studies on protein S to develop the drugs for anti-coagulation and anti-inflammation
- Principal Investigator
  
  SUZUKI Koji
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Hematology
- Research Institution
  Mie University
プロテインC凝固制御系異常症の分子病態学的研究
- Principal Investigator
  
  SUZUKI Koji
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Mie University
セルピン・エンザイム複合体(SEC)レセプターの構造と機能の研究Principal Investigator
- Principal Investigator
  
  武谷浩之
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Structural biochemistry
- Research Institution
  Mie University
Molecular bilogical studies on the assembly of the anticoagulant protein C pathway-Strucure-function relationship of the functional domains in the related molecules.
- Principal Investigator
  
  SUZUKI Koji
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  Mie University
セルピン・エンザイム複合体(SEC)レセプターの構造と機能の研究Principal Investigator
- Principal Investigator
  
  武谷浩之
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Structural biochemistry
- Research Institution
  Mie University
Development of Molecular Markers for Injured Endothelial Cells and Its Clinical Application
- Principal Investigator
  
  SUZUKI Koji
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  Laboratory medicine
- Research Institution
  Mie University
SECレセプターの単離、構造解析および機能発現機序の解明Principal Investigator
- Principal Investigator
  
  武谷浩之
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Structural biochemistry
- Research Institution
  Mie University
Studies on The Role of Functional Domains in Factors Playing in The Regulation of Thrombus Formation
- Principal Investigator
  
  SUZUKI Koji
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  Mie University
Molecular Mechanism of Extrinsic Blood Coagulation Pathway
- Principal Investigator
  
  IWANAGA Sadaaki
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Faculty of Science, Kyushu University
Initiation Mechanism of Extrinsic Blood Coagulation System
- Principal Investigator
  
  IWANAGA Sadaaki
- Project Period (FY)
  1988 – 1990
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Kyushu University

All 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2003 Other

All Journal Article Presentation Book Patent

[Book] Recent advances in Thrombosis and Hemostasis 20082008
- Author(s)
  Takeya, H., & Suzuki, K.
- Total Pages
  643
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-18659282
[Book] 図説分子病態学第4版2008
- Author(s)
  鈴木宏治、武谷浩之
- Total Pages
  472
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-18659282
[Book] 内皮細胞 in 血栓症ナビゲーター2006
- Author(s)
  武谷浩之
- Total Pages
  318
- Publisher
  メディカルビュー社
- Data Source
  KAKENHI-PROJECT-18659282
[Journal Article] Three dimensional structure of platelet ADP receptor P2Y122014
- Author(s)
  大野耕作、武谷浩之
- Journal Title
  
  Japanese Journal of Thrombosis and Hemostasis
  
  Volume: 25 Issue: 6 Pages: 472-477
- DOI
  10.2491/jjsth.25.742
- NAID
  130004847355
- ISSN
  0915-7441, 1880-8808
- Language
  Japanese
- Data Source
  KAKENHI-PROJECT-24659469
[Journal Article] Three dimensional structure of thrombin receptor PAR12013
- Author(s)
  千々岩崇仁、　武谷浩之
- Journal Title
  
  Japanese Journal of Thrombosis and Hemostasis
  
  Volume: 第24巻 Issue: 4 Pages: 454-459
- DOI
  10.2491/jjsth.24.454
- NAID
  130003367371
- ISSN
  0915-7441, 1880-8808
- Language
  Japanese
- Data Source
  KAKENHI-PROJECT-24659469
[Journal Article] Hot Topics 20122013
- Author(s)
  武谷浩之
- Journal Title
  
  Japanese Journal of Thrombosis and Hemostasis
  
  Volume: 24巻 Issue: 1 Pages: 62-63
- DOI
  10.2491/jjsth.24.60
- NAID
  130004847306
- ISSN
  0915-7441, 1880-8808
- Language
  Japanese
- Data Source
  KAKENHI-PROJECT-24659469
[Journal Article] Snake venom metalloproteinases: structure, function and relevance to the mammalian ADAM/ADAMTS family proteins2012
- Author(s)
  Takeda S, Takeya H, Iwanaga S
- Journal Title
  
  Biochim Biophys Acta: Proteins and Proteomics
  
  Volume: 1824 Pages: 164-176
- DOI
  10.1016/j.bbapap.2011.04.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659238, KAKENHI-PUBLICLY-23121536, KAKENHI-PROJECT-23570156
[Journal Article] リン脂質膜による凝固制御2012
- Author(s)
  武谷浩之
- Journal Title
  
  Thrombosis Medicine
  
  Volume: 2巻 Pages: 379-382
- Data Source
  KAKENHI-PROJECT-24659469
[Journal Article] 血栓症に関するQ&A:流血中の組織因子は血栓症の病態にどの程度関与しているのですか?2011
- Author(s)
  武谷浩之
- Journal Title
  
  血栓と循環
  
  Volume: 19 Pages: 53-55
- Data Source
  KAKENHI-PROJECT-21659238
[Journal Article] Effect of dibutyryl cyclic adenosine monophosphate on the gene expression of plasminogen activator inhibitor-1 and tissue factor in adipocytes2011
- Author(s)
  Taniguchi M, Ono N, Hayashi A, Yakura Y, Takeya H.
- Journal Title
  
  Thromb Res
  
  Volume: 128 Pages: 375-80
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659238
[Journal Article] Integration-free and stable expression of FVIII using a human artificial chromosome2011
- Author(s)
  Kurosaki H, et.al.
- Journal Title
  
  J.Hum.Genet.
  
  Volume: 56 Pages: 727-33
- DOI
  10.1038/jhg.2011.88
- NAID
  10030661356
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J00264, KAKENHI-PROJECT-21659238, KAKENHI-PROJECT-22590301, KAKENHI-PROJECT-23591426
[Journal Article] Sphingomyelin synthase 1-generated sphingomyelin plays an important role in transferrin trafficking and cell proliferation2011
- Author(s)
  Shakor AB, Taniguchi M, Kitatani K, Hashimoto M, Asano S, Hayashi A, Nomura K, Bielawski J, Bielawska A, Watanabe K, Kobayashi T, Igarashi Y, Umehara H, Takeya H, Okazaki T.
- Journal Title
  
  J Biol Chem
  
  Volume: 286 Pages: 36053-62
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659238
[Journal Article] 生物毒:血液毒-血栓・抗血栓性因子および出血因子2009
- Author(s)
  武谷浩之
- Journal Title
  
  生物の科学遺伝 Vol.63
  
  Pages: 14-18
- Data Source
  KAKENHI-PROJECT-21659238
[Journal Article] 細胞による凝固制御2009
- Author(s)
  武谷浩之
- Journal Title
  
  International Review of Thrombosis Vol.4
  
  Pages: 22-28
- Data Source
  KAKENHI-PROJECT-21659238
[Journal Article] 血液凝固抑制因子が出血リスクを軽減する2007
- Author(s)
  武谷浩之
- Journal Title
  
  蛋白質核酸酵素 52巻・2号
  
  Pages: 169-169
- Data Source
  KAKENHI-PROJECT-18659282
[Journal Article] 血中組織因子の産生細胞2007
- Author(s)
  武谷浩之
- Journal Title
  
  日本血栓止血学会誌 18
  
  Pages: 351-355
- NAID
  10026115112
- Data Source
  KAKENHI-PROJECT-18659282
[Journal Article] Synergistic effect of sphingosine 1-phosphage on thrombin-induced tissue factor expression in endothelial cells.2003
- Author(s)
  Takeya H, Gabazza EC, Aoki S, Ueno H, Suzuki K
- Journal Title
  
  Blood 102
  
  Pages: 1693-1700
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390255
[Patent] 内因系血液凝固反応のみを特異的に阻害する抗血栓剤2015
- Inventor(s)
  武谷浩之、田尻裕也、金子慎一郎
- Industrial Property Rights Holder
  武谷浩之、田尻裕也、金子慎一郎
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2015-034482
- Filing Date
  2015-02-14
- Data Source
  KAKENHI-PROJECT-24659469
[Patent] 線溶賦活剤2009
- Inventor(s)
  武谷浩之
- Industrial Property Rights Holder
  鳥取大学
- Acquisition Date
  2009-12-25
- Data Source
  KAKENHI-PROJECT-21659238
[Patent] 線溶賦活剤2009
- Inventor(s)
  武谷浩之
- Industrial Property Rights Holder
  鳥取大学
- Industrial Property Number
  2009-115734
- Filing Date
  2009-05-12
- Data Source
  KAKENHI-PROJECT-21659238
[Presentation] スフィンゴ脂質の代謝と機能2014
- Author(s)
  武谷浩之
- Organizer
  岡山県医用工学研究会シンポジウム
- Place of Presentation
  岡山大学鹿田キャンパス（岡山県岡山市）
- Year and Date
  2014-10-10
- Invited
- Data Source
  KAKENHI-PROJECT-24659469
[Presentation] 線虫のグルコース誘発性成長停止の分子機序2013
- Author(s)
  手柴衣理、宮原浩二、本山彩霞、武谷浩之
- Organizer
  第86回　日本生化学会大会
- Place of Presentation
  神奈川県横浜市パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-24659469
[Presentation] スフィンゴミエリン合成酵素機能の線虫を用いた解析2013
- Author(s)
  宮原浩二、田尻裕也、南條健太、武谷浩之
- Organizer
  第35回　日本血栓止血学会学術集会
- Place of Presentation
  山形県山形市山形国際ホテル
- Data Source
  KAKENHI-PROJECT-24659469
[Presentation] 線虫インスリン相同遺伝子ins-7の欠失変異体におけるグルコース誘発性成長停止の分子機序の解析2013
- Author(s)
  手柴衣理、宮原浩二、本山彩霞、武谷浩之
- Organizer
  第36回　日本分子生物学会年会
- Place of Presentation
  兵庫県神戸市神戸ポートアイランド
- Data Source
  KAKENHI-PROJECT-24659469
[Presentation] 線虫のインスリン相同遺伝子欠失変異体を用いた新規糖尿病治療薬スクリーニング系の開発2013
- Author(s)
  手柴衣理、宮原浩二、本山彩霞、武谷浩之
- Organizer
  平成25年度日本生化学会九州支部例会
- Place of Presentation
  佐賀県佐賀市佐賀大学
- Data Source
  KAKENHI-PROJECT-24659469
[Presentation] A loss-of-function mutant of the sphingomyelin synthase homologue SMS-1 in Caenorhabditis elegans.2013
- Author(s)
  K. Miyahara, K. Nanjo, Y. Tajiri, & H. Takeya
- Organizer
  8th AIM (Aso International Meeting)
- Place of Presentation
  熊本県阿蘇市ホテルグリーンピア南阿蘇
- Data Source
  KAKENHI-PROJECT-24659469
[Presentation] 人工染色体ベクターを用いた新規血友病A遺伝子治療法の開発2012
- Author(s)
  矢倉裕奈、黒崎創、石原千恵、香月康宏、土井健史、松下正、武谷浩之、押村光雄
- Organizer
  第11回日本再生医療学会総会
- Place of Presentation
  横浜
- Year and Date
  2012-06-14
- Data Source
  KAKENHI-PROJECT-21659238
[Presentation] ヒト人工染色体を用いた血小板特異的FVIII発現iPS細胞の作製-新規治療法確立へ向けて2012
- Author(s)
  矢倉裕奈、黒崎創、石原千恵、香月康宏、土井健史、武谷浩之、押村光雄
- Organizer
  第34回日本血栓止血学会学術集会
- Place of Presentation
  東京
- Year and Date
  2012-06-09
- Data Source
  KAKENHI-PROJECT-21659238
[Presentation] Transcription factor NFAT but not NF-KB is essential for thrombin-induced tissue factor expression2011
- Author(s)
  Yakura Y, Taniguchi M, Morimoto K, Hayashi A, Takeya H
- Organizer
  XXIII Congress of the International Society on Thrombosis and Haemostasis
- Place of Presentation
  京都
- Year and Date
  2011-07-28
- Data Source
  KAKENHI-PROJECT-21659238
[Presentation] Suppressive actions of fucoidan on lipid droplet formation and plasminogen activator inhibitor-1 expression in adipocytes2011
- Author(s)
  Hayashi A, Yakura Y, Taniguchi M, Tomita A, Takeya H
- Organizer
  XXIII Congress of the International Society on Thrombosis and Haemostasis
- Place of Presentation
  京都
- Year and Date
  2011-07-26
- Data Source
  KAKENHI-PROJECT-21659238
[Presentation] Regulation of leukotriene production and plasimonen activator inhibitor-1 expression in adipose tissue2011
- Author(s)
  Hayashi A, Taniguchi M, Yakura Y, Miyabara J, Yamamoto H, Kozutsumi Y, Okazaki T, Takeya H
- Organizer
  XXIII Congress of the International Society on Thrombosis and Haemostasis
- Place of Presentation
  京都
- Year and Date
  2011-07-26
- Data Source
  KAKENHI-PROJECT-21659238
[Presentation] ヒト人工染色体とiPS細胞を用いた新規血友病遺伝子治療法2011
- Author(s)
  矢倉裕奈、石原千恵、藤井昂洸、香月康宏、黒崎創、土井健史、小松則夫、押村光雄、武谷浩之
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2011-09-22
- Data Source
  KAKENHI-PROJECT-21659238
[Presentation] Thrombocytopenia in mice lacking sphingomyelin synthase 12011
- Author(s)
  Fujii, T, Hayashi A, Yakura Y, Taniguchi M, Watanabe K, Kitatani K, Okazaki T, Takeya H
- Organizer
  XXIII Congress of the International Society on Thrombosis and Haemostasis
- Place of Presentation
  京都
- Year and Date
  2011-07-25
- Data Source
  KAKENHI-PROJECT-21659238
[Presentation] Pathophysiology of thrombocytopenia in mice lacking sphingomyelin synthase 12010
- Author(s)
  武谷浩之
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  ポートアイランド(神戸)
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-21659238
[Presentation] トロンビンによる組織因子発現誘導にNF-κBの活性化は必須ではない2010
- Author(s)
  武谷浩之
- Organizer
  第33回日本血栓止血学会学術集会
- Place of Presentation
  城山観光ホテル(鹿児島)
- Year and Date
  2010-04-24
- Data Source
  KAKENHI-PROJECT-21659238
[Presentation] Mice lacking sphingomyelin synthase 1 exhibit thrombocytopenia2010
- Author(s)
  Hiroyuki Takeya
- Organizer
  2010 Keystone Symposia : Bioactive lipids
- Place of Presentation
  ウェスチン都(京都)
- Year and Date
  2010-06-07
- Data Source
  KAKENHI-PROJECT-21659238
[Presentation] スフィンゴミエリン合成酵素1の遺伝子欠損マウスは血小板数減少を来す2010
- Author(s)
  武谷浩之
- Organizer
  第33回日本血栓止血学会学術集会
- Place of Presentation
  城山観光ホテル(鹿児島)
- Year and Date
  2010-04-24
- Data Source
  KAKENHI-PROJECT-21659238
[Presentation] 血栓形成の分子機構2010
- Author(s)
  武谷浩之
- Organizer
  心臓血管フォーラム2010
- Place of Presentation
  モントレグラスミア(大阪)
- Year and Date
  2010-10-28
- Data Source
  KAKENHI-PROJECT-21659238
[Presentation] トロンビンによる組織因子の遺伝子発現誘導における転写因子の解析2010
- Author(s)
  武谷浩之
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  ポートアイランド(神戸)
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-21659238
[Presentation] スフィンゴミエリン合成酵素1-KOマウスの解析:血小板減少について2010
- Author(s)
  武谷浩之
- Organizer
  セラミド研究会第3回学術集会
- Place of Presentation
  東大弥生講堂(東京)
- Year and Date
  2010-10-28
- Data Source
  KAKENHI-PROJECT-21659238
[Presentation] スフィンゴシン1-リン酸によるMonocyte chemoattractant protein-1(MCP-1)の遺伝子発現誘導経路の解析2010
- Author(s)
  武谷浩之
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  ポートアイランド(神戸)
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-21659238
[Presentation] Development of human artificial chromosome vectors for gene therapy of hemophilia A2009
- Author(s)
  Yakura Y, Ishihara C, Hayashi A, Matsui T, Matsumoto S, Kurosaki H, Oshimura M, Doi T, Komatsu N, and Takeya H
- Organizer
  XXIIst Congress of the International Society on Thrombosis and Haemostasis
- Place of Presentation
  Boston
- Year and Date
  2009-07-16
- Data Source
  KAKENHI-PROJECT-21659238
[Presentation] ヒト人工染色体を用いた血小板特異的な第VIII因子発現系の確立2009
- Author(s)
  矢倉裕奈、石原千恵、林輝、松井俊樹、松本幸子、黒崎創、押村光雄、土井健史、小松則夫、武谷浩之
- Organizer
  第32回日本血栓止血学会学術集会
- Place of Presentation
  北九州
- Year and Date
  2009-06-04
- Data Source
  KAKENHI-PROJECT-21659238
[Presentation] ヒト人工染色体を用いた血小板特異的な第VIII因子発現系の確立2009
- Author(s)
  武谷浩之
- Organizer
  第32回日本血栓止血学会学術集会
- Place of Presentation
  北九州国際会議場(小倉)
- Year and Date
  2009-06-05
- Data Source
  KAKENHI-PROJECT-21659238
[Presentation] The ability of mature adipocytes to produce cysteinyl leukotrienes2009
- Author(s)
  Hiroyuki Takeya
- Organizer
  4^<th> International Conference on Phospholipase A2 and Lipid Madiators (PLM2009)
- Place of Presentation
  National Center of Sciences (Tokyo)
- Year and Date
  2009-05-27
- Data Source
  KAKENHI-PROJECT-21659238
[Presentation] The role of cAMP in the gene expression of plasminogen activator inhibitor-1 and tissue factor in adipocytes2009
- Author(s)
  Hiroyuki Takeya
- Organizer
  XXII Congress of the International Society on Thrombosis and Haemostasis
- Place of Presentation
  Boston, USA
- Year and Date
  2009-07-13
- Data Source
  KAKENHI-PROJECT-21659238
[Presentation] Development of human artificial chromosome vectors for gene therapy of hemophilia A2009
- Author(s)
  Hiroyuki Takeya
- Organizer
  XXII Congress of the International Society on Thrombosis and Haemostasis
- Place of Presentation
  Boston, USA
- Year and Date
  2009-07-16
- Data Source
  KAKENHI-PROJECT-21659238
[Presentation] Covalently associated dimers and multimers of β2-glycoprotein I2009
- Author(s)
  Hiroyuki Takeya
- Organizer
  XXII Congress of the International Society on Thrombosis and Haemostasis
- Place of Presentation
  Boston, USA
- Year and Date
  2009-07-14
- Data Source
  KAKENHI-PROJECT-21659238
[Presentation] 脂質ダイナミズムによる血栓止血反応の制御2007
- Author(s)
  武谷浩之
- Organizer
  第30回日本血栓止血学会学術集会
- Place of Presentation
  志摩市
- Year and Date
  2007-11-15
- Data Source
  KAKENHI-PROJECT-18659282
[Presentation] 線虫スフィンゴ脂質代謝系酵素遺伝子の欠失変異体の解析
- Author(s)
  林　知成、宮原浩二、田尻裕也、武谷浩之
- Organizer
  平成26年度日本生化学会九州支部例会
- Place of Presentation
  九州大学病院キャンパス（福岡県福岡市）
- Year and Date
  2014-05-17 – 2014-05-18
- Data Source
  KAKENHI-PROJECT-24659469
[Presentation] スフィンゴ脂質代謝系酵素遺伝子の欠失変異体の解析
- Author(s)
  林　知成、宮原浩二、田尻裕也、武谷浩之
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  国立京都国際会館（京都府京都市）
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-24659469
[Presentation] ハブ毒新規セリンプロテアーゼ様タンパク質の同定
- Author(s)
  清水安奈、千々岩崇仁、大栗誉敏、中村仁美、上田直子、武谷浩之
- Organizer
  平成26年度日本生化学会九州支部例会
- Place of Presentation
  九州大学病院キャンパス（福岡県福岡市）
- Year and Date
  2014-05-17 – 2014-05-18
- Data Source
  KAKENHI-PROJECT-24659469
[Presentation] 触媒三残基のHisがArgに置換したハブ毒新規セリンプロテアーゼ様タンパク質
- Author(s)
  清水安奈、千々岩崇仁、大栗誉敏、中村仁美、上田直子、武谷浩之
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  国立京都国際会館（京都府京都市）
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-24659469
[Presentation] グルコース誘発性成長停止に関与する遺伝子の線虫変異体の取得と解析
- Author(s)
  手柴衣理、宮原浩二、武谷浩之
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  国立京都国際会館（京都府京都市）
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-24659469
[Presentation] 線虫のグルコース誘発性成長停止に関与する遺伝子の変異体取得
- Author(s)
  手柴衣理、宮原浩二、武谷浩之
- Organizer
  平成26年度日本生化学会九州支部例会
- Place of Presentation
  九州大学病院キャンパス（福岡県福岡市）
- Year and Date
  2014-05-17 – 2014-05-18
- Data Source
  KAKENHI-PROJECT-24659469
[Presentation] 脂肪細胞によるβ2-glycoproteinⅠの共有結合性多量体化
- Author(s)
  栗山嵩史、武谷浩之
- Organizer
  第36回日本血栓止血学会学術集会
- Place of Presentation
  大阪国際交流センター（大阪府大阪市）
- Year and Date
  2014-05-29 – 2014-05-31
- Data Source
  KAKENHI-PROJECT-24659469

1. SUZUKI Koji (70077808)

# of Collaborated Projects: 13 results

# of Collaborated Products: 0 results
2. HAYASHI Tatsuya (00242959)

# of Collaborated Projects: 10 results

# of Collaborated Products: 0 results
3. IDO Masaru (90167263)

# of Collaborated Projects: 7 results

# of Collaborated Products: 0 results
4. IWANAGA Sadaaki (90029942)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. KAWABATA Shun-ichiro (90183037)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. SUEISHI Katsuo (70108710)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. ICHINOSE Akitada (10241689)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. KAMADA Haruhiko (00324509)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. DAVIE Earl . W

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. STENFLO Joha

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. DAHLBACK Bjo

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. INOUE Toshiaki (80305573)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. KATOH Motonobu (00273904)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. OHBAYASHI Tetsuya (80348804)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. NANBA Eiji (40237631)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. KUROSAKI Hajime (70464295)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
17. MIYAHARA Kohji (40325155)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
18. HIGASHI Shouichi (10275076)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. NAKAGAWA Kazunori (50217668)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. MUTA Tatsushi (60222337)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. UENO Hikaru (50260378)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
22. SASAGURI Yasuyuki (60140646)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. ASADA Yujiro (70202588)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. NISHIDA Takahiro (50284500)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. TOKUNAGA Fuminori (00212069)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. MIYATA Toshiyuki (90183970)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 吉留賢 (30325790)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 西村仁 (80241347)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 種田寛 (00236712)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. FUJIKAWA Kazuo

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. TAMEI Hironori

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. IWATA Kazushi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. TANABE Masataka

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. HONJO Eijiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. DAHLBACK Bjorn

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. STENFLO Johan

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. YAMAGISHI Toshiya

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
38. NAKA Daichi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
39. EARL W.Davie

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
40. 武田壮一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
41. 平塚正治

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
42. 三室淳

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

TAKEYA Hiroyuki 武谷 浩之

武谷 宏之 タケヤ ヒロユキ

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Sphingolipid metabolism in thrombosis and hemostasisPrincipal Investigator

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Human arterial chromosomes for new hemophilia therapyPrincipal Investigator

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組織因子による血管・リンパ管形成作用のオタマジャクシを用いた解析Principal Investigator

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The structure and function of molecules which regulate the cell membrane phospholipid bi-layer.Principal Investigator

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抗リン脂質抗体による血栓形成機序の分子病態学的解析Principal Investigator

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トロンビンおよびアンチトロンビンIIIによる細胞機能変換の分子機構Principal Investigator

TAKEYA Hiroyuki 武谷浩之

武谷宏之タケヤヒロユキ