KOKURA Kenji 古倉健嗣

… Alternative Names

古倉健嗣コクラケンジ

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Researcher Number	30344039
Other IDs
Affiliation (Current)	2025: 東邦大学, 理学部, 准教授
Affiliation (based on the past Project Information) *help	2020 – 2023: 東邦大学, 理学部, 准教授 2015 – 2018: 鳥取大学, 医学部, 助教 2003: 独立行政法人理化学研究所, 分子遺伝学研究室, 基礎科学特別研究 2002: 理化学研究所, 分子遺伝学研究室, 基礎科学特別研究員
Review Section/Research Field	Principal Investigator General pharmacology Except Principal Investigator Basic Section 45020:Evolutionary biology-related / Basic Section 44010:Cell biology-related / Genetics/Chromosome dynamics / Life / Health / Medical informatics / Biological Sciences
Keywords	Principal Investigator 人工染色体ベクター / IL-8遺伝子レポーター / IL-6遺伝子レポーター / 腎毒性 / 培養細胞 / ヒト腎臓培養細胞株 / 転写制御 / レポーター遺伝子 / 腎毒性試験 Except Principal Investigator 微小核 … More / p53 / M期停止 / 細胞死 / オートファジー / SIRT2 / 進化 / シャペロニン / 大腸菌 / 高温適応進化 / プロテオスタシス / Post-slippage cell death / Death in Mitosis / 四倍体化 / 抗がん剤 / Myc / p21 / アポトーシス / 四倍体 / 紡錘体チェックポイント / 合成生物学 / システム生物学 / インテグレース / ゲノム編集 / ゲノム改変技術 / 遺伝子改変技術 / 遺伝子工学 / 人工染色体ベクター / Structure / Drosophila / Mice / Development / Transcription factors / Transcription mediators / Transcription control / Gene expression / 立体構造 / ショウジョウバエ / マウス / 発生 / 転写因子 / 転写メディエーター / 転写制御 / 遺伝子発現 Less

Dynamics of proteostasis function during thermo-tolerant evolution of E. coli
- Principal Investigator
  
  Kishimoto Toshihiko
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 45020:Evolutionary biology-related
- Research Institution
  Toho University
Mechanism of cell death in tetraploid cells generated from mitotic slippage
- Principal Investigator
  
  井上敏昭
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 44010:Cell biology-related
- Research Institution
  Tottori University
Rapid and easy detection of nephrotoxicity using human cultured cell lines; application of IL-6/IL-8 reporter genePrincipal Investigator
- Principal Investigator
  
  KOKURA Kenji
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Tottori University
A gene expression control system using a genome exchange technology on a mammalian artificial chromosome vector
- Principal Investigator
  
  Tetsuya Ohbayashi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Life / Health / Medical informatics
- Research Institution
  Tottori University
A novel pathway of cell death in tertaploid generated after mitotic slippage
- Principal Investigator
  
  Toshiaki Inoue
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Genetics/Chromosome dynamics
- Research Institution
  Tottori University
Transcriptional control by mediators and their physiological significance
- Principal Investigator
  
  ISHII Shunsuke
- Project Period (FY)
  2002 – 2006
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Review Section
  
  Biological Sciences
- Research Institution
  The Institute of Physical and Chemical Research

All 2022 2021 2020 2019 2018 2017 2016 2003

All Journal Article Presentation

[Journal Article] Stabilization of P/CAF, as a ubiquitin ligase toward MDM2, suppresses mitotic cell death through p53-p21 activation in HCT116 cells with SIRT2 suppression.2019
- Author(s)
  Li Y, Kokura K, Inoue T.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 508 Issue: 1 Pages: 208-236
- DOI
  10.1016/j.bbrc.2018.11.136
- NAID
  120006776189
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06221, KAKENHI-PROJECT-16K08548
[Journal Article] Multiple expression cassette exchange via TP901-1, R4, and Bxb1 integrase systems on a mouse artificial chromosome.2017
- Author(s)
  Tomimatsu K, Kokura K, Nishida T, Yoshimura Y, Kazuki Y, Narita M, Oshimura M, Ohbayashi T.
- Journal Title
  
  FEBS Open Bio.
  
  Volume: 7 Issue: 3 Pages: 306-317
- DOI
  10.1002/2211-5463.12169
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25221308, KAKENHI-PROJECT-16K08548, KAKENHI-PROJECT-15K12141
[Journal Article] Evaluation of an Hprt-Luciferase Reporter Gene on a Mammalian Artificial Chromosome in Response to Cytotoxicity.2016
- Author(s)
  Endo T, Noda N, Kuromi Y, Kokura K, Kazuki Y, Oshimura M, Ohbayashi T.
- Journal Title
  
  Yonago Acta Med.
  
  Volume: 59 Pages: 174-182
- NAID
  120005775326
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08548
[Journal Article] 4.Kokura K, Kuromi Y, Endo T, Anzai N, Kazuki Y, Oshimura M, Ohbayashi T.2016
- Author(s)
  Kokura K, Kuromi Y, Endo T, Anzai N, Kazuki Y, Oshimura M, Ohbayashi T.
- Journal Title
  
  J Gene Med.
  
  Volume: 18 Issue: 10 Pages: 273-281
- DOI
  10.1002/jgm.2925
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25221308, KAKENHI-PROJECT-26461258, KAKENHI-PROJECT-16K08548
[Journal Article] The Ski-binding protein C184M negatively regulate TGF- β signaling by sequestering the Smad proteins to cytoplasm.2003
- Author(s)
  Kokura, K. et al.
- Journal Title
  
  J. Biol. Chem. 278
  
  Pages: 20133-20139
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14002011
[Journal Article] The Ski-binding protein C184M negatively regulate TGF-β signaling by sequestering the Smad proteins to cytoplasm.2003
- Author(s)
  Kokura, K. et al.
- Journal Title
  
  J. Biol. Chem. 278
  
  Pages: 20133-20139
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14002011
[Presentation] EMTをモニターするレポーター細胞株の樹立2022
- Author(s)
  戸邉理佳、岡島美空、奈良井節、中山裕二、岸本利彦、古倉健嗣
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20H03302
[Presentation] 大腸菌高温適応進化過程における進化の変遷2021
- Author(s)
  西広翔, 菅野暢, 小西隆介, 松尾萌, 古倉健嗣, 山内長承, 岸本利彦
- Organizer
  第44回日本分子生物学会年会、オンライン
- Data Source
  KAKENHI-PROJECT-20H03302
[Presentation] 大腸菌の高温進化における特性解析2021
- Author(s)
  西広翔, 山内長承, 木所恵利佳, 菅野暢, 小西隆介, 松尾萌, 古倉健嗣, 岸本利彦
- Organizer
  第23回日本進化学会年大会、オンライン
- Data Source
  KAKENHI-PROJECT-20H03302
[Presentation] 高温適応進化大腸菌におけるProteostasisの変異機能解析2020
- Author(s)
  菅野暢、山本椰香、西広翔、小西隆介、松尾萌、古倉健嗣、山内長承、岸本利彦
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20H03302
[Presentation] 大腸菌の高温適応進化とシャペロニンGroELの進化の相関2020
- Author(s)
  小西隆介、菅野暢、西広翔、松尾萌、古倉健嗣、山内長承、岸本利彦
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20H03302
[Presentation] 高温適応進化大腸菌の適応戦略2020
- Author(s)
  西広翔、木所恵利佳、小西隆介、菅野暢、松尾萌、古倉健嗣、山内長承、岸本利彦
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20H03302
[Presentation] 生細胞で骨分化をモニターできるヒト不死化間葉系幹細胞株の樹立2020
- Author(s)
  奈良井節, 綿世諒平, 中山祐二, 小谷勇, 井上敏昭, 古倉健嗣
- Organizer
  第19回日本再生医療学会
- Data Source
  KAKENHI-PROJECT-18K06221
[Presentation] 高温適応進化大腸菌におけるProteostasisの変異機能解析2020
- Author(s)
  菅野暢、西広翔、小西隆介、松尾萌、古倉健嗣、山内長承、岸本利彦
- Organizer
  第22回日本進化学会年大会
- Data Source
  KAKENHI-PROJECT-20H03302
[Presentation] 高温適応進化大腸菌の特性解析2020
- Author(s)
  西広翔、木所恵利佳、菅野暢、小西隆介、松尾萌、古倉健嗣、山内長承、岸本利彦
- Organizer
  第22回日本進化学会年大会
- Data Source
  KAKENHI-PROJECT-20H03302
[Presentation] 大腸菌の高温適応進化とシャペロニンGroELの進化の相関2020
- Author(s)
  小西隆介、西広翔、菅野暢、松尾萌、古倉健嗣、山内長承、岸本利彦
- Organizer
  第22回日本進化学会年大会
- Data Source
  KAKENHI-PROJECT-20H03302
[Presentation] CRISPR/CASを利用した新規骨分化ハイスループットスクリーニング系の樹立2019
- Author(s)
  奈良井節、綿世諒平、井上敏昭、古倉健嗣、小谷勇
- Organizer
  第18回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-16K08548
[Presentation] 骨分化の新規ハイスループットスクリーニング系樹立の試み2019
- Author(s)
  奈良井　節, 綿世諒平, 加藤基伸, 井上敏昭, 古倉健嗣, 小谷勇, 押村光雄
- Organizer
  第18回日本再生医療学会
- Data Source
  KAKENHI-PROJECT-18K06221
[Presentation] 生細胞で骨分化をモニタリングできるヒト間葉系幹細胞株の樹立2019
- Author(s)
  奈良井節, 綿世諒平, 古倉健嗣, 井上敏昭, 田村隆行, 小谷勇
- Organizer
  第48回(公社)日本口腔外科学会中国四国支部学術集会
- Data Source
  KAKENHI-PROJECT-18K06221
[Presentation] 骨分化の新規ハイスループットスクリーニング系樹立の試み2018
- Author(s)
  奈良井節、綿世諒平、加藤基伸、井上敏昭、古倉健嗣、小谷勇、押村光雄
- Organizer
  第59回日本生化学会　中国・四国支部例会
- Data Source
  KAKENHI-PROJECT-16K08548
[Presentation] 骨分化の新規ハイスループットスクリーニング系の樹立2018
- Author(s)
  奈良井節、綿世諒平、古倉健嗣、加藤基伸、押村光雄、井上敏昭、小谷勇
- Organizer
  第47回日本口腔外科学会中国四国支部学術集会
- Data Source
  KAKENHI-PROJECT-16K08548
[Presentation] 骨分化の新規ハイスループットスクリーニング系樹立2018
- Author(s)
  奈良井　節, 綿世諒平, 古倉健嗣, 加藤基伸, 押村光雄,井上敏昭, 小谷勇
- Organizer
  第47回(公社)日本口腔外科学会
- Data Source
  KAKENHI-PROJECT-18K06221
[Presentation] 腎幹前駆細胞による再構成ネフロン様構造体を用いたin vitro 腎毒性試験法2018
- Author(s)
  大林徹也、古倉健嗣、喜多村真治
- Organizer
  第45回日本毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-16K08548
[Presentation] 骨分化の新規ハイスループットスクリーニング系樹立の試み2018
- Author(s)
  奈良井節, 綿世諒平, 加藤基伸, 井上敏昭, 古倉健嗣, 小谷勇, 押村光雄
- Organizer
  第17回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-15K07158
[Presentation] マウス・ヒト細胞株を用いた簡便なin vitro腎毒性応答の検出2018
- Author(s)
  古倉健嗣、井上敏昭、安西尚彦、大林徹也
- Organizer
  第59回日本生化学会中国・四国支部例会
- Data Source
  KAKENHI-PROJECT-18K06221
[Presentation] 生細胞で骨分化をモニタリングできるヒト間葉系幹細胞株の樹立2018
- Author(s)
  奈良井　節,　綿世諒平,　古倉健嗣,　井上敏昭,　小谷勇
- Organizer
  第65回(公社)日本口腔外科学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-18K06221
[Presentation] 骨分化の新規ハイスループットスクリーニング系樹立の試み2018
- Author(s)
  奈良井節、綿世諒平、加藤基伸、井上敏昭、古倉健嗣、小谷勇、押村光雄
- Organizer
  第17回再生医療学会、横浜、2018
- Data Source
  KAKENHI-PROJECT-16K08548
[Presentation] 骨分化の新規ハイスループットスクリーニング系樹立の試み2018
- Author(s)
  奈良井節、綿世諒平、加藤基伸、井上敏昭、古倉健嗣、小谷勇、押村光雄
- Organizer
  第59回日本生化学会中国・四国支部例会
- Data Source
  KAKENHI-PROJECT-18K06221
[Presentation] マウス・ヒト細胞株を用いた簡便なin vitro腎毒性応答の検出2018
- Author(s)
  古倉健嗣、井上敏昭、安西尚彦、大林徹也
- Organizer
  第59回日本生化学会　中国・四国支部例会
- Data Source
  KAKENHI-PROJECT-16K08548

1. Toshiaki Inoue (80305573)

# of Collaborated Projects: 3 results

# of Collaborated Products: 21 results
2. Tetsuya Ohbayashi (80348804)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
3. ISHII Shunsuke (00124785)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. SHIMADA Nobukazu (80391978)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. ISHIDAO Takefumi (20391857)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. Kishimoto Toshihiko (90339200)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
7. 品川敏恵 (70344041)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 田中康範 (80311348)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 高木豪 (70300879)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 中村和臣 (90598137)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 中山祐二 (40432603)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 河野暢明 (90647356)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. Li Yanze

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 押村光雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

KOKURA Kenji 古倉 健嗣

古倉 健嗣 コクラ ケンジ

Research Projects

Research Products

Co-Researchers

Dynamics of proteostasis function during thermo-tolerant evolution of E. coli

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mechanism of cell death in tetraploid cells generated from mitotic slippage

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Rapid and easy detection of nephrotoxicity using human cultured cell lines; application of IL-6/IL-8 reporter genePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A gene expression control system using a genome exchange technology on a mammalian artificial chromosome vector

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A novel pathway of cell death in tertaploid generated after mitotic slippage

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Transcriptional control by mediators and their physiological significance

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Stabilization of P/CAF, as a ubiquitin ligase toward MDM2, suppresses mitotic cell death through p53-p21 activation in HCT116 cells with SIRT2 suppression.2019

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Multiple expression cassette exchange via TP901-1, R4, and Bxb1 integrase systems on a mouse artificial chromosome.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Evaluation of an Hprt-Luciferase Reporter Gene on a Mammalian Artificial Chromosome in Response to Cytotoxicity.2016

Author(s)

Journal Title

NAID

Data Source

[Journal Article] 4.Kokura K, Kuromi Y, Endo T, Anzai N, Kazuki Y, Oshimura M, Ohbayashi T.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The Ski-binding protein C184M negatively regulate TGF- β signaling by sequestering the Smad proteins to cytoplasm.2003

Author(s)

Journal Title

Description

Data Source

[Journal Article] The Ski-binding protein C184M negatively regulate TGF-β signaling by sequestering the Smad proteins to cytoplasm.2003

Author(s)

Journal Title

Description

Data Source

[Presentation] EMTをモニターするレポーター細胞株の樹立2022

Author(s)

Organizer

Data Source

[Presentation] 大腸菌高温適応進化過程における進化の変遷2021

Author(s)

Organizer

Data Source

KOKURA Kenji 古倉健嗣

古倉健嗣コクラケンジ