Takata Kazuyuki 高田和幸

… Alternative Names

TAKATA Kazuyuki 高田和幸

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Researcher Number	10434664
Other IDs
Affiliation (Current)	2025: 京都薬科大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2020 – 2023: 京都薬科大学, 薬学部, 教授 2018: 京都薬科大学, 薬学部, 教授 2015 – 2017: 京都薬科大学, 薬学部, 准教授 2007 – 2014: Kyoto Pharmaceutical University, 薬学部, 助教 2006: 京都薬科大学, 薬学部, 助手
Review Section/Research Field	Principal Investigator Biological pharmacy / Basic Section 51030:Pathophysiologic neuroscience-related / Pharmacology in pharmacy / Medical pharmacy / Applied pharmacology Except Principal Investigator Basic Section 49030:Experimental pathology-related / Neurochemistry/Neuropharmacology
Keywords	Principal Investigator アルツハイマー病 / ミクログリア / アミロイドβ / 貪食 / 神経保護 / 移植 / iPS細胞 / 骨髄幹細胞 / 骨髄細胞 / トランスジェニックマウス … More / DJ-1 / Smad2/3 / 造血幹細胞 / TGF-β1 / 線条体 / ヒト人工多能性幹細胞 / 多様性 / イメージング / 化合物 / 生薬成分 / 病態 / 老化 / 脳内免疫環境 / ヒトiPS細胞 / ホットスポット / 疾患関連ミクログリア / 神経細胞死 / オルガノイド / 脳免疫 / 幹細胞 / iPS / シナプス / 認知機能 / クリアランス / 分化誘導 / ミクログリア様細胞 / 末梢血造血幹細胞 / 細胞移植療法 / transplantation / bone marrow cells / stem cells / clearance / amyloid-beta / phagocytosis / microglia / Alzheimer's disease / 脳神経疾患 / トランスレーショナルリサーチ / 痴呆 / 神経科学 / 移植・再生医療 / allosterically potentiating ligand / 再生医療 / macrophage-colony stimulating factor / アロステリック活性化リガンド / ガランタミン / ニコチン性アセチルコリン受容体 / 剖検脳 / 細胞骨格タンパク質 / 神経原線維変化 / ペナンブラ / 中大脳動脈閉塞モデル / electron spin resonance / 抗酸化作用 / パーキンソン病 / アストロサイト / アクチン重合 / シナプス破綻 / 脳梗塞 / 神経障害部位 / ラット / MRI / 抗アミロイドβ抗体 / サイトカイン / 糖鎖 / 免疫療法 … More Except Principal Investigator 炎症性細胞 / 記憶学習障害 / 炎症関連遺伝子 / 脳発達 / ミクログリア / ダウン症候群 / ノックアウトマウス / 質量分析 / HRD1 / Dorfin / RNF1９B / 神経細胞 / EDAD / 小胞体ストレス / 小胞体 / エンドソーム / RNF19B / 膜輸送 / γ-セクレターゼ / 酸化ストレス / ERAD / アミロイドβ / APP / ユビキチンリガーゼ / アルツハイマー病 Less

Understanding the mechanisms underlying bran developmental retardation in Down syndrome
- Principal Investigator
  
  石原慶一
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  Kyoto Pharmaceutical University
Elucidation of the pathophysiology of Alzheimer's disease by analysis of changes in the immune environment in the brain and its application to the treatmentPrincipal Investigator
- Principal Investigator
  
  Takata Kazuyuki
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Kyoto Pharmaceutical University
Functional analysis of stem cell derived-Abeta phagocytic cells for the development of cell therapeutic strategies in Alzheimer's diseasePrincipal Investigator
- Principal Investigator
  
  Takata Kazuyuki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pharmacology in pharmacy
- Research Institution
  Kyoto Pharmaceutical University
Transplantation of bone marrow-derived microglia-like cells for the new cell therapy against Alzheimer's diseasePrincipal Investigator
- Principal Investigator
  
  TAKATA Kazuyuki
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Kyoto Pharmaceutical University
Involvement of novel ubiquitin ligases in the pathogenic mechanism of Alzheimer's disease and drug discovery for fundamental therapeutic agent
- Principal Investigator
  
  Nomura Yasuyuki
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Kurume University
  Yokohama College of Pharmacy
Development of a novel therapeutic strategy for Alzheimer's disease targeting on nicotinic acetylcholine receptors on microgliaPrincipal Investigator
- Principal Investigator
  
  TAKATA Kazuyuki
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Kyoto Pharmaceutical University
Developmental challenges for drug delivery system targetin g to neurodegenerative areaPrincipal Investigator
- Principal Investigator
  
  TAKATA Kazuyuki
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Applied pharmacology
- Research Institution
  Kyoto Pharmaceutical University
アルツハイマー病新規治療戦略を指向したミクログリア機能制御の研究Principal Investigator
- Principal Investigator
  
  高田和幸
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (Start-up)
- Research Field
  
  Biological pharmacy
- Research Institution
  Kyoto Pharmaceutical University

[Book] 認知症の早期診断技術と進行抑制/予防薬・機能性食品の開発2019
- Author(s)
  濱進, 高田和幸
- Total Pages
  518
- Publisher
  技術情報協会
- ISBN
  9784861047442
- Data Source
  KAKENHI-PROJECT-16K08286
[Book] Development of Cell Therapeutic Strategies for Alzheimer’s Disease Using Animal Models. Animal Models in Human Disease: Applications, Outcomes and Controversies2013
- Author(s)
  Kazuyuki Takata et al.
- Total Pages
  162
- Publisher
  NOVA Science Publishers
- Data Source
  KAKENHI-PROJECT-24590222
[Book] Chapter 8 : Microglial functions against amyloid-β accumulation in brains of Alzheimer's disease. Microglia : Biology, Functions and Roles in Disease, Edited by Charanjit Kaur and Ling Eng-Ang2012
- Author(s)
  Kazuyuki Takata and Yoshihisa Kitamura
- Publisher
  NOVA Science Publishers(in press)
- Data Source
  KAKENHI-PROJECT-22790090
[Book] Chapter 8 : Microglial functions against amyloid-β accumulation in brains of Alzheimer's disease. Microglia : Biology, Functions and Roles in Disease2012
- Author(s)
  Kazuyuki Takata, et al
- Publisher
  NOVA Science Publishers(In press)
- Data Source
  KAKENHI-PROJECT-22790090
[Book] Microglia: Biology, Functions and Roles in Disease2012
- Author(s)
  Kazuyuki Takata et al.
- Total Pages
  321
- Publisher
  NOVA Science Publishers
- Data Source
  KAKENHI-PROJECT-24590222
[Journal Article] Suppression ofSleeping Beauty-induced Gliomagenicity in Ts1Cje Mice, a Model of Down Syndrome2024
- Author(s)
 ISHIHARA KEIICHI、SAKODA RYUTO、MIZOGUCHI MASAKO、FUJITA MITSUGU、MOYAMA CHIAMI、OKUTANI YURI、TAKATA KAZUYUKI、TANAKA MIWA、MINAMI TAKASHI、SAGO HARUHIKO、YAMAKAWA KAZUHIRO、NAKAMURA TAKURO、KAWASHITA ERI、AKIBA SATOSHI、NAKATA SUSUMU
- Journal Title
 
 Anticancer Research
 
 Volume: 44 Issue: 2 Pages: 489-495
- DOI
 10.21873/anticanres.16836
- Peer Reviewed
- Data Source
 KAKENHI-PROJECT-22K07033, KAKENHI-PROJECT-22K07653, KAKENHI-PROJECT-23K06642, KAKENHI-PROJECT-23K08554, KAKENHI-PROJECT-21K09167, KAKENHI-PUBLICLY-22H04822
[Journal Article] Host-to-graft propagation of inoculated α-synuclein into transplanted human induced pluripotent stem cell-derived midbrain dopaminergic neurons2024
- Author(s)
  Gima Serina、Oe Kazuya、Nishimura Kaneyasu、Ohgita Takashi、Ito Haruka、Kimura Hiroyuki、Saito Hiroyuki、Takata Kazuyuki
- Journal Title
  
  Regenerative Therapy
  
  Volume: 25 Pages: 229-237
- DOI
  10.1016/j.reth.2023.12.019
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06556, KAKENHI-PROJECT-22K07382, KAKENHI-PROJECT-21K15245, KAKENHI-PROJECT-20H03569
[Journal Article] CRISPR-Cas9-Edited SNCA Knockout Human Induced Pluripotent Stem Cell-Derived Dopaminergic Neurons and Their Vulnerability to Neurotoxicity2023
- Author(s)
 Inoue Shizen、Nishimura Kaneyasu、Gima Serina、Nakano Mai、Takata Kazuyuki
- Journal Title
 
 Biological and Pharmaceutical Bulletin
 
 Volume: 46 Issue: 3 Pages: 517-522
- DOI
 10.1248/bpb.b22-00839
- ISSN
 0918-6158, 1347-5215
- Year and Date
 2023-03-01
- Language
 English
- Peer Reviewed
- Data Source
 KAKENHI-PROJECT-22K07382, KAKENHI-PROJECT-20H03569
[Journal Article] Expression and role of nicotinic acetylcholine receptors during midbrain dopaminergic neuron differentiation from human induced pluripotent stem cells2023
- Author(s)
  Kato Takeshi、Nishimura Kaneyasu、Hirao Masahiro、Shimohama Shun、Takata Kazuyuki
- Journal Title
  
  Neuropsychopharmacology Reports
  
  Volume: 43 Issue: 3 Pages: 440-445
- DOI
  10.1002/npr2.12361
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07382, KAKENHI-PROJECT-20H03569
[Journal Article] Plantainoside B in Bacopa monniera Binds to Aβ Aggregates Attenuating Neuronal Damage and Memory Deficits Induced by Aβ2023
- Author(s)
 Fukuda Aina、Nakashima Souichi、Oda Yoshimi、Nishimura Kaneyasu、Kawashima Hidekazu、Kimura Hiroyuki、Ohgita Takashi、Kawashita Eri、Ishihara Keiichi、Hanaki Aoi、Okazaki Mizuki、Matsuda Erika、Tanaka Yui、Nakamura Seikou、Matsumoto Takahiro、Akiba Satoshi、Saito Hiroyuki、Matsuda Hisashi、Takata Kazuyuki
- Journal Title
 
 Biological and Pharmaceutical Bulletin
 
 Volume: 46 Issue: 2 Pages: 320-333
- DOI
 10.1248/bpb.b22-00797
- ISSN
 0918-6158, 1347-5215
- Year and Date
 2023-02-01
- Language
 English
- Peer Reviewed / Open Access
- Data Source
 KAKENHI-PROJECT-21K06637, KAKENHI-PROJECT-22K06556, KAKENHI-PROJECT-22K07382, KAKENHI-PROJECT-21K15245, KAKENHI-PROJECT-20H03569
[Journal Article] Involvement of an Aberrant Vascular System in Neurodevelopmental, Neuropsychiatric, and Neuro-Degenerative Diseases2023
- Author(s)
  Ishihara K., Takata K. & Mizutani K.
- Journal Title
  
  Life
  
  Volume: 13 Issue: 1 Pages: 221-221
- DOI
  10.3390/life13010221
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06802, KAKENHI-PROJECT-22K07033, KAKENHI-PUBLICLY-22H04822
[Journal Article] Analysis of Aβ-induced neurotoxicity and microglial responses in simple two- and three-dimensional human iPSC-derived cortical culture systems2023
- Author(s)
  Takata Mayuko、Nishimura Kaneyasu、Harada Koki、Iwasaki Ryota、Ando Momona、Yamada Shiho、Ginhoux Florent、Takata Kazuyuki
- Journal Title
  
  Tissue and Cell
  
  Volume: 81 Pages: 102023-102023
- DOI
  10.1016/j.tice.2023.102023
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07382, KAKENHI-PROJECT-20H03569
[Journal Article] Rapid conversion of human induced pluripotent stem cells into dopaminergic neurons by inducible expression of two transcription factors2022
- Author(s)
  Nishimura Kaneyasu、Nitta Tatsumi、Doi Keisuke、Takata Kazuyuki
- Journal Title
  
  Stem Cells and Development
  
  Volume: 印刷中 Issue: 11-12 Pages: 269-277
- DOI
  10.1089/scd.2021.0363
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07854, KAKENHI-PROJECT-22K07382, KAKENHI-PROJECT-20H03569
[Journal Article] Nicotinic Acetylcholine Receptors and Microglia as Therapeutic and Imaging Targets in Alzheimer’s Disease2022
- Author(s)
  Takata Kazuyuki、Kimura Hiroyuki、Yanagisawa Daijiro、Harada Koki、Nishimura Kaneyasu、Kitamura Yoshihisa、Shimohama Shun、Tooyama Ikuo
- Journal Title
  
  Molecules
  
  Volume: 27 Issue: 9 Pages: 2780-2780
- DOI
  10.3390/molecules27092780
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07854, KAKENHI-PROJECT-21K06586, KAKENHI-PROJECT-22K07382, KAKENHI-PROJECT-20H03569
[Journal Article] Generation of striatal neurons from human induced pluripotent stem cells by controlling extrinsic signals with small molecules2021
- Author(s)
  Amimoto Naoya、Nishimura Kaneyasu、Shimohama Shun、Takata Kazuyuki
- Journal Title
  
  Stem Cell Research
  
  Volume: 55 Pages: 102486-102486
- DOI
  10.1016/j.scr.2021.102486
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07854, KAKENHI-PROJECT-20H03569
[Journal Article] Roles of microglia in Alzheimer’s disease and impact of new findings on microglial heterogeneity as a target for therapeutic intervention2021
- Author(s)
  Takata Kazuyuki、Ginhoux Florent、Shimohama Shun
- Journal Title
  
  Biochemical Pharmacology
  
  Volume: 192 Pages: 114754-114754
- DOI
  10.1016/j.bcp.2021.114754
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03569
[Journal Article] Combination of Drugs and Cell Transplantation: More Beneficial Stem Cell-Based Regenerative Therapies Targeting Neurological Disorders2021
- Author(s)
  Nishimura Kaneyasu、Takata Kazuyuki
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 16 Pages: 9047-9047
- DOI
  10.3390/ijms22169047
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07854, KAKENHI-PROJECT-20H03569
[Journal Article] Mouse Bone Marrow-derived Microglia-like Cells Secrete Transforming Growth Factor-β1 and Promote Microglial Aβ Phagocytosis and Reduction of Brain Aβ2020
- Author(s)
  Kuroda E, Nishimura K, Kawanishi S, Sueyoshi M, Ueno F, Toji Y, Abo N, Konishi T, Harada K, Satake S, Shima C, Toda Y, Kitamura Y, Shimohama S, Ashihara E, Takata K.
- Journal Title
  
  Neuroscience
  
  Volume: 438 Pages: 217-228
- DOI
  10.1016/j.neuroscience.2020.05.004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K17388, KAKENHI-PROJECT-20H03569, KAKENHI-PROJECT-18K06904
[Journal Article] Bone-marrow-derived microglia-like cells ameliorate brain amyloid pathology and cognitive impairment in a mouse model of Alzheimer's disease.2018
- Author(s)
  Kawanishi S., Takata K., Itezono S., Nagayama H., Konoya S., Chisaki Y., Toda Y., Nakata S., Yano Y., Kitamura Y., Ashihara E.
- Journal Title
  
  J. Alzheimer’s Dis.
  
  Volume: 64 Issue: 2 Pages: 563-585
- DOI
  10.3233/jad-170994
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06904, KAKENHI-PROJECT-16K08286, KAKENHI-PROJECT-16K08722
[Journal Article] 脳老化タンパク質除去と幹細胞の応用2018
- Author(s)
  河西翔平、高田和幸
- Journal Title
  
  月刊「細胞」
  
  Volume: 50 Pages: 327-330
- Data Source
  KAKENHI-PROJECT-16K08286
[Journal Article] 認知症の克服に向けた幹細胞の応用2018
- Author(s)
  河西翔平、高田和幸
- Journal Title
  
  アグリバイオ
  
  Volume: 2 Pages: 79-83
- NAID
  40021808102
- Data Source
  KAKENHI-PROJECT-16K08286
[Journal Article] Bone-marrow-derived microglia-like cells ameliorate brain amyloid pathology and cognitive impairment in a mouse model of Alzheimer's disease2018
- Author(s)
  Kawanishi S., Takata K., et al.
- Journal Title
  
  Journal of Alzheimer’s Disease
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08286
[Journal Article] Alpha7 nicotinic acetylcholine receptor-specific agonist DMXBA (GTS-21) attenuates Aβ accumulation through suppression of neuronal γ-secretase activity and promotion of microglial amyloid-β phagocytosis and ameliorates cognitive impairment in a mouse model of Alzheimer's disease.2018
- Author(s)
  Takata K., et al.
- Journal Title
  
  Neurobiol Aging
  
  Volume: 62 Pages: 197-209
- DOI
  10.1016/j.neurobiolaging.2017.10.021
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08286, KAKENHI-PROJECT-16H05279
[Journal Article] Effects of a DJ-1-binding compound on spatial learning and memory impairment in a mouse model of Alzheimer's disease2017
- Author(s)
  Kitamura Y, Inden M, Kimoto K, Takata K, Yanagisawa D, Hijioka M, Ashihara K, Tooyama I, Shimohama S, Ariga H
- Journal Title
  
  Journal of Alzheimer’s Disease
  
  Volume: 55 Issue: 1 Pages: 67-72
- DOI
  10.3233/jad-160574
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K16321, KAKENHI-PROJECT-16K08286, KAKENHI-PROJECT-16H05279
[Journal Article] Poised for action: USP18 restrains microglial activation in the white matter2015
- Author(s)
  Kazuyuki Takata and Florent Ginhoux
- Journal Title
  
  The EMBO Journal
  
  Volume: 未定 Issue: 12 Pages: 1603-1605
- DOI
  10.15252/embj.201591899
- Data Source
  KAKENHI-PROJECT-24590222
[Journal Article] Effective internalization of U251-MG-secreted exosomes into cancer cells and characterization of their lipid components2015
- Author(s)
  Toda, Y., Takata, K., Nakagawa, Y., Kawakami, H., Fujioka, S., Kobayashi, K., Hattori Y., Kitamura, Y., Akaji, K., Ashihara, E.
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 456 Issue: 3 Pages: 768-773
- DOI
  10.1016/j.bbrc.2014.12.015
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-14J02568, KAKENHI-PROJECT-24590222
[Journal Article] Effects of oxidative stress on the solubility of HRD1, a ubiquitin ligaseimplicated in Alzheimer's disease2014
- Author(s)
  Saito R., Kaneko M., Kitamura Y., et al.
- Journal Title
  
  PLoS ONE
  
  Volume: 9巻 Issue: 5 Pages: 94576-94576
- DOI
  10.1371/journal.pone.0094576
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-13J09807, KAKENHI-PROJECT-23790095, KAKENHI-PROJECT-24300135, KAKENHI-PROJECT-24590119, KAKENHI-PROJECT-24790085, KAKENHI-PROJECT-26460099
[Journal Article] Effects of oxidative stress on the solubility of HRD1, a ubiquitin ligase implicated in Alzheimer's disease2014
- Author(s)
  Saito R., Kaneko M., Kitamura Y.,Takata K., Kawada K., Okuma Y. and Nomura Y.
- Journal Title
  
  PLos One
  
  Volume: 9
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24300135
[Journal Article] Therapeutic effects of human mesenchymal and hematopoietic stem cells on rotenone-treated parkinsonian mice2013
- Author(s)
  Inden M, Takata K, Nishimura K, Kitamura Y, Ashihara E, Yoshimoto K, Ariga H, Honmou O, Shimohama S
- Journal Title
  
  Journal of Neuroscience Research
  
  Volume: 91 Issue: 1 Pages: 62-72
- DOI
  10.1002/jnr.23128
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390180, KAKENHI-PROJECT-23591404, KAKENHI-PROJECT-23659460, KAKENHI-PROJECT-24590222, KAKENHI-PROJECT-25460109
[Journal Article] Molecular approaches to the treatment, prophylaxis, and diagnosis of Alzheimer's disease : tangle formation, amyloid-β, and microglia in Alzheimer's disease2012
- Author(s)
  Kazuyuki Takata and Yoshihisa Kitamura
- Journal Title
  
  J. Pharmacol Sci
  
  Volume: 188 Pages: 338-344
- NAID
  10030455494
- Data Source
  KAKENHI-PROJECT-22790090
[Journal Article] Molecular Approaches to the Treatment, Prophylaxis, and Diagnosis of Alzheimer’s Disease: Tangle Formation, Amyloid-β, and Microglia in Alzheimer’s Disease2012
- Author(s)
 Kazuyuki Takata, et al
- Journal Title
 
 J Pharmacol Sci
 
 Volume: 118 Issue: 3 Pages: 331-337
- DOI
 10.1254/jphs.11R10FM
- NAID
 10030455494
- ISSN
 1347-8613, 1347-8648
- Language
 English
- Peer Reviewed
- Data Source
 KAKENHI-PROJECT-22790090
[Journal Article] Microglial Amyloid-β1-40 Phagocytosis Dysfunction Is Caused by High-Mobility Group Box Protein-1: Implications for the Pathological Progression of Alzheimer's Disease.2012
- Author(s)
  Kazuyuki Takata et al.
- Journal Title
  
  International Journal of Alzheimer's Disease
  
  Volume: 2012 Pages: 1-11
- DOI
  10.1155/2012/685739
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590222
[Journal Article] Preparation and characterization of microglia-like cells derived from rat, mouse, and human bone marrow cells for therapeutic strategy of Alzheimer's disease2011
- Author(s)
  Kazuyuki Takata, Tetsuya Takada, Hironori Tatsuda, Tomomi Tsuruno, Kaneyasu Nishimura, Shun Shimohama, and Yoshihisa Kitamura
- Journal Title
  
  J. Addict. Res. Ther
  
  Volume: S5 Pages: 1-5
- DOI
  10.4172/2155-6105.s5-001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790090
[Journal Article] Galantamine-induced amyloid-β clearance mediated via stimulation of microglial nicotinic acetylcholine receptors2010
- Author(s)
  Kazuyuki Takata, Yoshihisa Kitamura, Mana Saeki, Maki Terada, Sachiko Kagitani, Risa Kitamura, Yasuhiro Fujikawa, Alfred Maelicke, Hidekazu Tomimoto, Takashi Taniguchi, and Shun Shimohama
- Journal Title
  
  J. Biol. Chem
  
  Volume: 285 Pages: 40180-40191
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790090
[Journal Article] Galantamine-induced amyloid-β clearance mediated via stimulation of microglial nicotinic acetylcholine receptors.2010
- Author(s)
  Kazuyuki Takata, et al.
- Journal Title
  
  J.Biol.Chem.
  
  Volume: 285 Pages: 40180-40191
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790090
[Journal Article] Involvement of WAVE Accumulation in A β/APP Pathology-Dependent Tangle Modification in Alzheimer's Disease2009
- Author(s)
  Kazuyuki Takata, et.al.
- Journal Title
  
  Am. J. Pathol (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790403
[Journal Article] Involvement of WAVE Accumulation in Aβ/APP Pathology- Dependent Tangle Modification in Alzheimer's Disease.2009
- Author(s)
  Kazuyuki Takata, Yoshihisa Kitamura, Yukinori Nakata, Yasuji Matsuoka, Hidekazu Tomimoto, Takashi Taniguchi, Shun Shimohama
- Journal Title
  
  Am. J. Pathol. 175
  
  Pages: 17-24
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790403
[Journal Article] Oxidative stress induction of DJ-1 protein in reactive astrocytes scavenges free radicals and reduces cell injury.2009
- Author(s)
  Takashi Yanagida, Jun Tsushima, Yoshihisa Kitamura, Daijiro Yanagisawa, Kazuyuki Takata, Tomonori Shibaike, Atsuko Yamamoto, Takashi Taniguchi, Hiroyuki Yasui, Takahiro Taira, Shigehiro Morikawa, Toshiro Inubushi, Ikuo Tooyama, Hiroyoshi Ariga
- Journal Title
  
  Oxi. Med. Cell. Long. 2
  
  Pages: 36-42
- NAID
  120005350101
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790403
[Journal Article] Deglycosylated anti-amyloid beta antibodies reduce microglial phagocytosis and cytokine production while retaining the capacity to induce amyloid beta sequestration2007
- Author(s)
  Kazuyuki Takata, et. al.
- Journal Title
  
  Eur.J.Neurosci. 26
  
  Pages: 2458-2674
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18890218
[Journal Article] Microglial transplantation increases amyloid-beta clearance in Alzheimer model rats.2007
- Author(s)
  Kazuyuki Takata et al.
- Journal Title
  
  FEBS Letters 581・3
  
  Pages: 475-478
- Data Source
  KAKENHI-PROJECT-18890218
[Presentation] ヒトiPS細胞由来ミクログリア前駆細胞と大脳皮質神経または脳オルガノイドの共培養系におけるAβ誘発細胞応答性の解析2024
- Author(s)
  安藤ももな, 西村周泰, 原田考輝, 山田志歩, 岩崎良太, 高田和幸
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-20H03569
[Presentation] アルツハイマー病の脳病態を再現する大脳皮質オルガノイド作製の試み2024
- Author(s)
  高田和幸, 西村周泰
- Organizer
  MPS実用化推進協議会第1回学術シンポジウム
- Data Source
  KAKENHI-PROJECT-20H03569
[Presentation] Bacopa monnieraに含有されるAβ結合物質plantainoside BによるAβ凝集体の検出と神経保護作用2023
- Author(s)
  福田愛菜, 中嶋聡一, 尾田好美, 西村周泰, 河嶋秀和, 木村寛之, 扇田隆司, 河下映里, 石原慶一, 花木葵, 岡崎瑞紀, 松田英里香, 田中雪衣, 中村誠宏, 松本崇宏, 秋葉聡, 斎藤博幸, 松田久司, 高田和幸
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-20H03569
[Presentation] ミクログリア・原始マクロファージ発生におけるニコチン性アセチルコリン受容体の機能解析2023
- Author(s)
  原田考輝、高田和幸
- Organizer
  第6回Neuro-Vascular研究会
- Data Source
  KAKENHI-PROJECT-20H03569
[Presentation] ミクログリア含有脳オルガノイドの作製と神経変性疾患研究への応用2023
- Author(s)
  高田和幸
- Organizer
  第97回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-20H03569
[Presentation] ヒトiPS細胞由来ミクログリア前駆細胞と大脳皮質神経または脳オルガノイドの共培養系におけるアミロイドβストレス負荷の解析2023
- Author(s)
  原田考輝, 西村周泰, 岩崎良太, 安藤ももな, 山田志歩, 高田和幸
- Organizer
  第66回日本神経化学会大会
- Data Source
  KAKENHI-PROJECT-20H03569
[Presentation] ミクログリア様細胞を含む脳オルガノイド作製とアルツハイマー病病態解析への応用2023
- Author(s)
  原田考輝, 西村周泰, 山田志歩, 岩崎良太, 安藤ももな, 高田和幸
- Organizer
  第64回日本組織細胞化学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-20H03569
[Presentation] ミクログリアを含有するヒトiPS細胞由来脳オルガノイドにおけるアミロイドβオリゴマーに対する細胞反応性の解析2023
- Author(s)
  原田考輝, 西村周泰, 山田志歩, 岩崎良太, 安藤ももな, 高田和幸
- Organizer
  生体機能と創薬シンポジウム2023
- Data Source
  KAKENHI-PROJECT-20H03569
[Presentation] 多様性が織りなすシナジー研究に向けて2023
- Author(s)
  高田和幸
- Organizer
  第4回和漢医薬学会若手研究者フォーラム
- Invited
- Data Source
  KAKENHI-PROJECT-20H03569
[Presentation] 脳に移植したヒトiPS細胞由来ドパミン神経へのα-シヌクレイン伝播の評価2023
- Author(s)
  儀間芹菜, 西村周泰, 扇田隆司, 斎藤博幸, 高田和幸
- Organizer
  次世代を担う若手のための創薬・医療薬理シンポジウム2023
- Data Source
  KAKENHI-PROJECT-20H03569
[Presentation] ヒトiPS細胞由来ミクログリア含有脳オルガノイドのアルツハイマー病研究への応用例2023
- Author(s)
  高田和幸, 原田考輝, 山田志歩, 岩崎良太, 安藤ももな, 西村周泰
- Organizer
  第9回細胞凝集研究会
- Data Source
  KAKENHI-PROJECT-20H03569
[Presentation] ミクログリア含有ヒトiPS細胞由来脳オルガノイドを用いたAβ誘発細胞応答性の解析2023
- Author(s)
  安藤ももな, 原田考輝, 西村周泰, 山田志歩, 岩崎良太, 高田和幸
- Organizer
  第42回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-20H03569
[Presentation] 生薬由来Aβ結合性低分子化合物の神経保護作用の解析2022
- Author(s)
  松田英里香、福田愛菜、中嶋聡一、尾田好美、花木葵、河嶋秀和、木村寛之、岡崎瑞紀、田中雪衣、中村誠宏、松田久司、西村周泰、高田和幸
- Organizer
  第41回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-20H03569
[Presentation] Effects of Down syndrome genes on amyloid-β aggregation in mice2022
- Author(s)
  Keiichi Ishihara, Eri Kawashita, Kaneyasu Nishimura, Michiko Saito, Haruhiko Sago, Kazuhiro Yamakawa, Satoshi Akiba, Kazuyuki Takata
- Organizer
  The 65th Annual Meeting of the Japanese Society for Neurochemistry
- Data Source
  KAKENHI-PROJECT-20H03569
[Presentation] Roles of nicotinic acetylcholine receptors on the differentiation of pluripotent stem cell-derived primitive macrophages and dopaminergic neurons2022
- Author(s)
  Koki Harada, Takeshi Kato, Masahiro Hirao, Kaneyasu Nishimura, Shun Shimohama, Kazuyuki Takata
- Organizer
  The 65th Annual Meeting of the Japanese Society for Neurochemistry
- Data Source
  KAKENHI-PROJECT-20H03569
[Presentation] Stem cell-derived microglia and Alzheimer’s disease2022
- Author(s)
  Kazuyuki Takata
- Organizer
  Joint symposium: Novel Approaches On PET Research-Total-Body Imaging, Radiopharmaceuticals, And Machine Learning.
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03569
[Presentation] Bacopa monniera由来Aβ結合性低分子化合物によるAβの検出と神経保護作用の解析2022
- Author(s)
  福田愛菜、中嶋聡一、尾田好美、西村周泰、花木葵、河嶋秀和、木村寛之、中村誠宏、松本崇宏、岡崎瑞紀、松田英里香、田中雪衣、松田久司、高田和幸
- Organizer
  日本生薬学会第68回年会
- Data Source
  KAKENHI-PROJECT-20H03569
[Presentation] 黒質線条体経路を再現する多領域性を持つ脳モデルの作製2022
- Author(s)
  西村周泰、網本直弥、中野舞、高田和幸
- Organizer
  第21回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-20H03569
[Presentation] 生薬由来低分子化合物のAβ神経毒性に対する保護作用とAβイメージングに向けた解析2022
- Author(s)
  福田愛菜、中嶋聡一、尾田好美、西村周泰、花木葵、河嶋秀和、木村寛之、中村誠宏、松本崇宏、高田和幸
- Organizer
  第96回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-20H03569
[Presentation] Suppressive effects of Down syndrome genes on amyloid-β aggregation and mortality in a mouse model of Alzheimer’s disease2022
- Author(s)
  Keiichi Ishihara, Eri Kawashita, Mizuki Katsuda, Michiko Saito, Haruhiko Sago, Kazuhiro Yamakawa, Satoshi Akiba1, Kazuyuki Takata
- Organizer
  The 67th Annual Meeting of the Japan Society of Human Genetics
- Data Source
  KAKENHI-PROJECT-20H03569
[Presentation] 脳発生と老化における神経細胞と脳内移住細胞との相互作用2021
- Author(s)
  高田和幸
- Organizer
  第44回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03569
[Presentation] iPS細胞由来マクロファージおよびドパミン神経の分化におけるアセチルコリン受容体の役割2021
- Author(s)
  原田考輝、加藤丈使、西村周泰、平尾真大、下濱俊、高田和幸
- Organizer
  第94回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-20H03569
[Presentation] アルツハイマー病と脳内微量金属元素2021
- Author(s)
  高田和幸
- Organizer
  第21回日本抗加齢医学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03569
[Presentation] 脳オルガノイドを活用した脳内免疫環境変化の解析と認知症の病態解明への応用2021
- Author(s)
  高田和幸、高田真優子、西村周泰
- Organizer
  第40回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-20H03569
[Presentation] 脳内免疫環境の構築におけるミクログリアの役割と脳疾患との関連性の解明とiPS細胞由来ミクログリア様細胞の応用2021
- Author(s)
  高田和幸
- Organizer
  第62回日本組織細胞化学会総会・学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03569
[Presentation] 骨髄細胞由来ミクログリア様細胞のミクログリアとの相互作用ならびにニコチン受容体刺激による機能制御の解析2020
- Author(s)
  末吉真梨、西村周秦、北村佳久、芦原英司、下濱俊、高田和幸
- Organizer
  第70回日本薬学会関西支部大会
- Data Source
  KAKENHI-PROJECT-20H03569
[Presentation] 脳内免疫細胞ミクログリアとアルツハイマー病の細胞治療戦略2020
- Author(s)
  高田和幸
- Organizer
  第14回次世代を担う若手医療薬科学シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-20H03569
[Presentation] 認知症の細胞治療戦略開発に向けた幹細胞由来ミクログリア様細胞の機能解析とその制御2020
- Author(s)
  末吉真梨、西村周泰、芦原英司、下濱俊、高田和幸
- Organizer
  第39回日本認知症学会
- Data Source
  KAKENHI-PROJECT-20H03569
[Presentation] アルツハイマー病病理におけるミクログリアの意義と治療を指向した機能制御2020
- Author(s)
  高田和幸
- Organizer
  第52回日本動脈硬化化学会総会・学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03569
[Presentation] ミクログリアの発生過程から迫る認知症治療戦略の開発2019
- Author(s)
  高田和幸
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-16K08286
[Presentation] 幹細胞由来免疫細胞を用いた認知症の治療戦略2018
- Author(s)
  高田和幸
- Organizer
  第61回日本神経化学会大会
- Data Source
  KAKENHI-PROJECT-16K08286
[Presentation] 幹細胞由来ミクログリア様細胞を用いた認知症細胞治療戦略2018
- Author(s)
  高田和幸
- Organizer
  第37回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-16K08286
[Presentation] 認知症克服へ向けた脳の基礎研究とその展望「脳の免疫がアルツハイマー病克服のカギを握る！？」2018
- Author(s)
  高田和幸
- Organizer
  京都産業21・けいはんなオープンイノベーションセンター（KICK）第13回大学リレーセミナー
- Invited
- Data Source
  KAKENHI-PROJECT-16K08286
[Presentation] γ-セクレターゼ活性およびミクログリアの貪食機能を介したα７ニコチン受容体特異的刺激薬DMXBAのアミロイドβ蓄積抑制作用の解析2018
- Author(s)
  高田和幸、黒田絵莉子、河西翔平、戸田侑紀、下濱　俊、芦原英司
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-16K08286
[Presentation] 髄由来アミロイドβ貪食細胞の機能解析およびアルツハイマー病モデルマウスへの脳内移植2017
- Author(s)
  河西翔平、高田和幸、射手園将真、長山紘子、黒田絵莉子、戸田侑紀、芦原英司
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台国際センター
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-16K08286
[Presentation] マウス末梢血由来造血幹細胞からミクログリア様細胞への分化誘導とその機能解析2017
- Author(s)
  黒田絵莉子、高田和幸、河西翔平、戸田侑紀、芦原英司
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台国際センター
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-16K08286
[Presentation] iPS細胞を用いたアルツハイマー病細胞治療の可能性2017
- Author(s)
  高田和幸
- Organizer
  第21回大文字クラブ
- Place of Presentation
  ベーコンラボ京都駅3階
- Invited
- Data Source
  KAKENHI-PROJECT-16K08286
[Presentation] Microglia as a therapeutic target for Alzheimer's disease2014
- Author(s)
  Kazuyuki Takata, Yoshihisa Kitamura, Florent Ginhoux and Eishi Ahishira
- Organizer
  Monthly Neuroscience Seminar in Faculty of Medicine & Health Science, University Putra Malaysia
- Place of Presentation
  Faculty of Medicine & Health Science, University Putra Malaysia　(Serdang, Malaysia)
- Year and Date
  2014-10-15
- Invited
- Data Source
  KAKENHI-PROJECT-24590222
[Presentation] A novel therapeutic target against Alzheimer's disease: HRD1 as endolplasmic reticulum stress-related ubiquitin ligase2014
- Author(s)
  Nomura Y, Kaneko M, Okuma Y, Kitamura Y, Takata Y, Nishi A
- Organizer
  13th International Geneva/Springfield Symposium on Advances in Alzheimer Therapy
- Place of Presentation
  Geneve, Switzerland
- Invited
- Data Source
  KAKENHI-PROJECT-24300135
[Presentation] アルツハイマー病の細胞治療法開発に向けた骨髄由来細胞のAβ貪食細胞と内在性ミクログリアへの作用解析.2014
- Author(s)
  杜氏裕美子、高田和幸ら
- Organizer
  日本薬学会第134年会
- Place of Presentation
  ホテル日航熊本ほか（熊本県）
- Data Source
  KAKENHI-PROJECT-24590222
[Presentation] アルツハイマー病の根本的治療を目指した治療標的の探索と双方向性橋渡し研究2013
- Author(s)
  高田和幸
- Organizer
  日本薬学会第133年会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Invited
- Data Source
  KAKENHI-PROJECT-24590222
[Presentation] アルツハイマー病克服に向けたトランスレーショナルリサーチ2013
- Author(s)
  高田和幸ら
- Organizer
  第86回日本薬理学会
- Place of Presentation
  福岡国際会議場（福岡県）
- Data Source
  KAKENHI-PROJECT-24590222
[Presentation] Microglia-like monocytic cells derived from bone marrow cells phagocytose amyloid-β and facilitate phagocytosis of amyloid-β by resident microglia.2013
- Author(s)
  Kazuyuki Takata et al.
- Organizer
  American Society of Hematology 55th annual meeting
- Place of Presentation
  New Orleans Ernest N. Morial Convention Center (New Orleans, USA)
- Data Source
  KAKENHI-PROJECT-24590222
[Presentation] M-CSF刺激による造血幹細胞からのアミロイドβ貪食細胞への分化誘導.2013
- Author(s)
  高田和幸ら
- Organizer
  第７５回日本血液学会学術総会
- Place of Presentation
  ロイトン札幌ほか（北海道）
- Data Source
  KAKENHI-PROJECT-24590222
[Presentation] Monocytes derived from bone marrow cells by macrophage colony-stimulating factor treatment effectively phagocytose amyloid-β.2012
- Author(s)
  Kazuyuki Takata et al.
- Organizer
  ISEH-Society for Hematology and Stem Cells-41st Annual Scientific Meeting
- Place of Presentation
  Hotel OKura (Amsterdam, Netherlands)
- Data Source
  KAKENHI-PROJECT-24590222
[Presentation] Translational research on compensatory microglial function for therapeutic strategy of Alzheimer's disease2011
- Author(s)
  Kazuyuki Takata and Yoshihisa Kitamura
- Organizer
  第5回次世代を担う若手医療薬科学シンポジウム
- Place of Presentation
  名古屋大学医学部附属病院(愛知県)
- Year and Date
  2011-11-27
- Data Source
  KAKENHI-PROJECT-22790090
[Presentation] ガランタミンによるミクログリアのアミロイドβ貪食促進作用2011
- Author(s)
  高田和幸, 他
- Organizer
  日本薬学会第131年会
- Place of Presentation
  ツインメッセ静岡(静岡県)
- Year and Date
  2011-03-30
- Data Source
  KAKENHI-PROJECT-22790090
[Presentation] ニコチン性アセチルコリン受容体のアロステリック制御によるミクログリアのアミロイドβ貪食促進作用の解析2011
- Author(s)
  高田和幸、北村佳久、下濱俊、谷口隆之
- Organizer
  第84回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2011-03-23
- Data Source
  KAKENHI-PROJECT-22790090
[Presentation] ガランタミンによるミクログリアのアミロイドβ貪食促進作用2011
- Author(s)
  高田和幸、北村佳久、谷口隆之
- Organizer
  日本薬学会第131年会
- Place of Presentation
  ツインメッセ静岡(静岡県)
- Year and Date
  2011-03-30
- Data Source
  KAKENHI-PROJECT-22790090
[Presentation] アミロイドβ蛋白質依存性アルツハイマー病病変の研究2010
- Author(s)
  高田和幸, 他
- Organizer
  日本薬学会第130年会
- Place of Presentation
  就実大学(岡山)
- Year and Date
  2010-03-29
- Data Source
  KAKENHI-PROJECT-20790403
[Presentation] アミロイドβ蛋白質依存性アルツハイマー病病変の研究2010
- Author(s)
  高田和幸, 他
- Organizer
  日本薬学会第130年会
- Place of Presentation
  就実大学(岡山)
- Year and Date
  2010-03-29
- Data Source
  KAKENHI-PROJECT-20790403
[Presentation] アルツハイマー病におけるアミロイドβ依存性の神経原線維変化成熟化に関する解析2010
- Author(s)
  高田和幸, 他
- Organizer
  第83回日本薬理学会年会
- Place of Presentation
  大阪国際会議場(大阪)
- Year and Date
  2010-03-17
- Data Source
  KAKENHI-PROJECT-20790403
[Presentation] 抗アミロイドβ抗体によるミクログリアのアミロイドβ貪食機能制御2009
- Author(s)
  高田和幸, 他
- Organizer
  第82回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜(神奈川)
- Year and Date
  2009-03-16
- Data Source
  KAKENHI-PROJECT-20790403
[Presentation] 抗アミロイドβ抗体によるミクログリアのアミロイドβ貪食機能制御2009
- Author(s)
  高田和幸, 他
- Organizer
  第82回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2009-03-16
- Data Source
  KAKENHI-PROJECT-20790403
[Presentation] アルツハイマー病ワクチン療法戦略における抗Aβ抗体のミクログリアに対する作用2009
- Author(s)
  高田和幸, 他
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都国際会議場
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-20790403
[Presentation] アルツハイマー病ワクチン療法戦略における抗Aβ抗体のミクログリアに対する作用2009
- Author(s)
  高田和幸, 他
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都国際会議場(京都)
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-20790403
[Presentation] アルツハイマー病モデルラットを用いたミクログリア移植によるアミロイドβの分解促進2008
- Author(s)
  高田和幸, 他
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜会議センターG会場
- Year and Date
  2008-03-19
- Data Source
  KAKENHI-PROJECT-18890218
[Presentation] M-CSFを処置した骨髄由来アミロイドβ貪食細胞の加齢に伴う機能変化の解析.
- Author(s)
  河西　翔平、高田　和幸ら
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸学院大学ほか（兵庫県）
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-24590222

1. KITAMURA Yoshihisa (60195295)

# of Collaborated Projects: 5 results

# of Collaborated Products: 6 results
2. Shimohama Shun

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
3. 石原慶一 (80340446)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
4. 西村周泰 (90527889)

# of Collaborated Projects: 2 results

# of Collaborated Products: 25 results
5. 谷口隆之

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
6. 富本秀和

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. Nomura Yasuyuki (00034041)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. Sobue Gen (20148315)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. Okuma Yasunobu (20127939)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
10. Tomobe Koji (80460286)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. Kaneko Masayuki (10322827)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
12. Ishigaki Shinsuke (40378170)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. Kawada Koichi (30581631)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
14. Ashihara Eishi

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
15. Chisaki Yugo

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. Toda Yuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
17. Nakata Susumu

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. Yano Yoshitaka

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 遠山育夫

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 有賀寛芳

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 平敬宏

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 犬伏俊郎

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 森川茂廣

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 安井裕之

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 松岡康治

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 柳沢大治郎

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
27. 柳田孝志

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 中田行紀

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 芝池知徳

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 津島純

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. 山本温子

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. ALFRED Maelicke

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
33. 佐伯真菜

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. 寺田真希

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. 鍵谷沙智子

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. 北村理紗

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
37. 辰田博則

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
38. 高田哲也

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
39. 藤川靖浩

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
40. 鶴野友美

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
41. MIZUTANI Kenichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
42. 本望修

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
43. 斎藤博幸

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Takata Kazuyuki 高田 和幸

TAKATA Kazuyuki 高田 和幸

Research Projects

Research Products

Co-Researchers

Understanding the mechanisms underlying bran developmental retardation in Down syndrome

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Elucidation of the pathophysiology of Alzheimer's disease by analysis of changes in the immune environment in the brain and its application to the treatmentPrincipal Investigator

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Functional analysis of stem cell derived-Abeta phagocytic cells for the development of cell therapeutic strategies in Alzheimer's diseasePrincipal Investigator

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Transplantation of bone marrow-derived microglia-like cells for the new cell therapy against Alzheimer's diseasePrincipal Investigator

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Involvement of novel ubiquitin ligases in the pathogenic mechanism of Alzheimer's disease and drug discovery for fundamental therapeutic agent

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Development of a novel therapeutic strategy for Alzheimer's disease targeting on nicotinic acetylcholine receptors on microgliaPrincipal Investigator

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Developmental challenges for drug delivery system targetin g to neurodegenerative areaPrincipal Investigator

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アルツハイマー病新規治療戦略を指向したミクログリア機能制御の研究Principal Investigator

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[Book] 認知症の早期診断技術と進行抑制/予防薬・機能性食品の開発2019

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[Book] Development of Cell Therapeutic Strategies for Alzheimer’s Disease Using Animal Models. Animal Models in Human Disease: Applications, Outcomes and Controversies2013

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[Book] Chapter 8 : Microglial functions against amyloid-β accumulation in brains of Alzheimer's disease. Microglia : Biology, Functions and Roles in Disease, Edited by Charanjit Kaur and Ling Eng-Ang2012

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[Book] Chapter 8 : Microglial functions against amyloid-β accumulation in brains of Alzheimer's disease. Microglia : Biology, Functions and Roles in Disease2012

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[Book] Microglia: Biology, Functions and Roles in Disease2012

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[Journal Article] Suppression of<i>Sleeping Beauty</i>-induced Gliomagenicity in Ts1Cje Mice, a Model of Down Syndrome2024

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Takata Kazuyuki 高田和幸

TAKATA Kazuyuki 高田和幸