Ando Kiyohiro 安藤清宏

… Alternative Names

安藤清宏アンドウキヨヒロ

ANDO KIYOHIRO 安藤清宏

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Researcher Number	10455389
Other IDs
Affiliation (Current)	2025: 地方独立行政法人埼玉県立病院機構埼玉県立がんセンター(臨床腫瘍研究所), 臨床腫瘍研究所, 副部長 2025: 千葉県がんセンター(研究所), 研究所, 客員研究員
Affiliation (based on the past Project Information) *help	2021 – 2023: 地方独立行政法人埼玉県立病院機構埼玉県立がんセンター(臨床腫瘍研究所), 臨床腫瘍研究所, 副部長 2020: 埼玉県立がんセンター(臨床腫瘍研究所), 臨床腫瘍研究所, 副部長 2018 – 2019: 昭和大学, 大学共同利用機関等の部局等, 講師 2018 – 2019: 日本大学, 医学部, 兼任講師 2017: 日本大学, 医学部, 助教 2014: 千葉県がんセンター(研究所), がん治療開発グループ, 客員研究員 2013: 千葉県がんセンター(研究所), がん先進治療開発研究室, 客員研究員
Review Section/Research Field	Principal Investigator Basic Section 50010:Tumor biology-related / General medical chemistry Except Principal Investigator Pediatric surgery / Basic Section 55010:General surgery and pediatric surgery-related
Keywords	Principal Investigator CHK1 / neuroblastoma / checkpoint kinase 1 / 10q loss / CHP134 / p63 / DNA-PK / ATM / FGFR２ / kinase inhibitor … More / ERK / MEK / DNA損傷修復 / MYCN / DNA-PK阻害剤 / MEK阻害剤 / FGFR2 / CEP131 / DNA損傷応答 / 神経芽腫 / CHK1阻害剤 / ICRF-193 / TOPOIIalpha / アポトーシス / キナーゼ阻害 / 遺伝子 / 癌 / TP53 / decatenation checkpoint / topoisomerase / PLK1 / MDC1 / NFBD1 … More Except Principal Investigator 腎芽腫 / バイオマーカー / Caspase-2 / 分裂期崩壊 / 分裂期チェックポイント / VUVCD / SNP / Myc-nick / ORFドミナンス / 細胞死 / 分裂期 / MYCN / NCYM / 神経芽腫 / 小児腫瘍学 / リスク分類 / 小児腎腫瘍 / 腎腫瘍 / 小児がん / 癌 / 外科 / miRNA / リキッドバイオプシー / microRNA / エキソソーム / 腎ラブドイド腫瘍 Less

Elucidation of the mechanism of mitotic regulation by NCYM and its contribution to neuroblastoma tumorigenesis
- Principal Investigator
  
  Suenaga Yusuke
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Chiba Cancer Center (Research Institute)
Clinical application and biomarker of CHK1 inhibitor-mediated cell deathPrincipal Investigator
- Principal Investigator
  
  Ando Kiyohiro
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Research Institute for Clinical Oncology Saitama Cancer Center
  Showa University
A study of liquid biopsy using exosomes for neuroblastoma and pediatric renal tumors.
- Principal Investigator
  
  UEHARA Shuichiro
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatric surgery
- Research Institution
  Nihon University
A novel strategy for pediatric renal tumors using biomarkers as indicators
- Principal Investigator
  
  KOSHINAGA Tsugumichi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatric surgery
- Research Institution
  Nihon University
Potential anticancer effect by inhibiting NFBD1/MDC1Principal Investigator
- Principal Investigator
  
  ANDO KIYOHIRO
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  General medical chemistry
- Research Institution
  Chiba Cancer Center (Research Institute)

All 2021 2020 2019 2018 2017 2013 Other

All Journal Article Presentation

[Journal Article] Acceleration or Brakes: Which Is Rational for Cell Cycle-Targeting Neuroblastoma Therapy?2021
- Author(s)
  Ando Kiyohiro、Nakagawara Akira
- Journal Title
  
  Biomolecules
  
  Volume: 11 Issue: 5 Pages: 750-750
- DOI
  10.3390/biom11050750
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07246
[Journal Article] FGFR2 loss sensitizes MYCN‐amplified neuroblastoma CHP134 cells to CHK1 inhibitor?induced apoptosis2021
- Author(s)
  Ando Kiyohiro、Ohira Miki、Takada Ichiro、Cazares‐Ordonez Verna、Suenaga Yusuke、Nagase Hiroki、Kobayashi Shinichi、Koshinaga Tsugumichi、Kamijo Takehiko、Makishima Makoto、Wada Satoshi
- Journal Title
  
  Cancer Science
  
  Volume: 113 Issue: 2 Pages: 587-596
- DOI
  10.1111/cas.15205
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07246, KAKENHI-PROJECT-20K08269, KAKENHI-PROJECT-19H03625
[Journal Article] TAp63 represses transcription of MYCN/NCYM gene and its high levels of expression are associated with favorable outcome in neuroblastoma2019
- Author(s)
  Suenaga Yusuke、Yamamoto Mami、Sakuma Tetsushi、Sasada Manabu、Fukai Fumio、Ohira Miki、Yamaguchi Yohko、Yamamoto Takashi、Ando Kiyohiro、Ozaki Toshinori、Nakagawara Akira
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 518 Issue: 2 Pages: 311-318
- DOI
  10.1016/j.bbrc.2019.08.052
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07246, KAKENHI-PROJECT-19K16111, KAKENHI-PROJECT-17K10131
[Journal Article] Co-Inhibition of the DNA Damage Response and CHK1 Enhances Apoptosis of Neuroblastoma Cells2019
- Author(s)
  Ando Kiyohiro、Nakamura Yohko、Nagase Hiroki、Nakagawara Akira、Koshinaga Tsugumichi、Wada Satoshi、Makishima Makoto
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 20 Issue: 15 Pages: 3700-3700
- DOI
  10.3390/ijms20153700
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07246
[Journal Article] NFBD1/MDC1 is phosphorylated by PLK1 and controls G2/M transition through the regulation of a TOPOIIα-mediated decatenation checkpoint.2013
- Author(s)
  Ando K, Ozaki T, Hirota T, Nakagawara A.
- Journal Title
  
  PLoS One
  
  Volume: e82744 Issue: 12 Pages: 0-0
- DOI
  10.1371/journal.pone.0082744
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23501278, KAKENHI-PUBLICLY-24114517, KAKENHI-PROJECT-24249061, KAKENHI-PROJECT-24370076, KAKENHI-PROJECT-25893292
[Presentation] CHK1阻害剤はFGFR2-MEK-ERK経路の抑制に相乗的に神経芽腫の増殖を抑制する2021
- Author(s)
  安藤清宏
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K07246
[Presentation] FGFR2の欠失はCHK1阻害剤が誘導する細胞死の感受性を増強する2020
- Author(s)
  安藤清宏、大平美紀、末永雄介、上條岳彦、永瀬浩喜、小林真一、和田聡
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K07246
[Presentation] MDM2はp53とcentrosome-associated family proteinとの結合によりCHK1阻害剤感受性を増強する2019
- Author(s)
  安藤清宏
- Organizer
  第61回　日本小児血液・がん学会
- Data Source
  KAKENHI-PROJECT-18K07246
[Presentation] checkpoint abrogationを応用した神経芽腫治療の可能性2018
- Author(s)
  安藤清宏
- Organizer
  第60回　日本小児血液・がん学会学術総会
- Data Source
  KAKENHI-PROJECT-18K07246
[Presentation] 日本ウィルムス腫瘍スタディグループの臨床試験結果からみた小児腎腫瘍に対する外科的アプローチと治療戦略験2017
- Author(s)
  大植孝治、佐々木隆士、安藤清宏、越永従道
- Organizer
  第79回臨床外科学会総会
- Data Source
  KAKENHI-PROJECT-17H04356
[Presentation] NFBD1/MDC1 はPlk1 によるリン酸化を介してDecatenation Checkpoint に関連したG2/M 期進行を制御する
- Author(s)
  安藤清宏
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-25893292
[Presentation] CHK１阻害剤はMYCN増幅神経芽腫のp53非依存的アポトーシスを誘導する
- Author(s)
  安藤清宏、佐藤勉、小林修三
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-25893292

1. KOSHINAGA Tsugumichi (70205376)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
2. Suenaga Yusuke (80581793)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
3. UEHARA Shuichiro (00448060)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 川島弘之 (60645703)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 野崎美和子 (10175523)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 瀧本哲也 (40393178)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 陳基明 (50277422)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 大植孝治 (50314315)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. 大喜多肇 (50317260)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 井上永介 (50528338)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 春田雅之 (80392190)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 谷ヶ崎博 (90378141)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 筆宝義隆 (30359632)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 尾崎俊文

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ando Kiyohiro 安藤 清宏

安藤 清宏 アンドウ キヨヒロ

ANDO KIYOHIRO 安藤 清宏

Research Projects

Research Products

Co-Researchers

Elucidation of the mechanism of mitotic regulation by NCYM and its contribution to neuroblastoma tumorigenesis

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Clinical application and biomarker of CHK1 inhibitor-mediated cell deathPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

A study of liquid biopsy using exosomes for neuroblastoma and pediatric renal tumors.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A novel strategy for pediatric renal tumors using biomarkers as indicators

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Potential anticancer effect by inhibiting NFBD1/MDC1Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Acceleration or Brakes: Which Is Rational for Cell Cycle-Targeting Neuroblastoma Therapy?2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] FGFR2 loss sensitizes MYCN‐amplified neuroblastoma CHP134 cells to CHK1 inhibitor?induced apoptosis2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] TAp63 represses transcription of MYCN/NCYM gene and its high levels of expression are associated with favorable outcome in neuroblastoma2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Co-Inhibition of the DNA Damage Response and CHK1 Enhances Apoptosis of Neuroblastoma Cells2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] NFBD1/MDC1 is phosphorylated by PLK1 and controls G2/M transition through the regulation of a TOPOIIα-mediated decatenation checkpoint.2013

Author(s)

Journal Title

DOI

Data Source

[Presentation] CHK1阻害剤はFGFR2-MEK-ERK経路の抑制に相乗的に神経芽腫の増殖を抑制する2021

Author(s)

Organizer

Data Source

[Presentation] FGFR2の欠失はCHK1阻害剤が誘導する細胞死の感受性を増強する2020

Author(s)

Organizer

Data Source

[Presentation] MDM2はp53とcentrosome-associated family proteinとの結合によりCHK1阻害剤感受性を増強する2019

Author(s)

Organizer

Data Source

[Presentation] checkpoint abrogationを応用した神経芽腫治療の可能性2018

Author(s)

Organizer

Data Source

[Presentation] 日本ウィルムス腫瘍スタディグループの臨床試験結果からみた小児腎腫瘍に対する外科的アプローチと治療戦略 験2017

Author(s)

Organizer

Ando Kiyohiro 安藤清宏

安藤清宏アンドウキヨヒロ

ANDO KIYOHIRO 安藤清宏

[Presentation] 日本ウィルムス腫瘍スタディグループの臨床試験結果からみた小児腎腫瘍に対する外科的アプローチと治療戦略験2017