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arai chihiro  新井 千博

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ARAI Chihiro  新井 千博

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Researcher Number 10460221
Affiliation (Current) 2025: 鶴見大学, 歯学部, 臨床教授
Affiliation (based on the past Project Information) *help 2020 – 2023: 鶴見大学, 歯学部, 非常勤講師
2019: 鶴見大学, 歯学部, 学内講師
2010 – 2018: 鶴見大学, 歯学部, 助教
Review Section/Research Field
Principal Investigator
Basic Section 57070:Developmental dentistry-related / Orthodontic/Pediatric dentistry / Orthodontics/Pediatric dentistry
Except Principal Investigator
Orthodontic/Pediatric dentistry / Orthodontics/Pediatric dentistry
Keywords
Principal Investigator
歯科矯正学 / 歯の移動 / 矯正学的歯の移動 / Heat Shock Protein / 歯根膜線維芽細胞 / 歯周組織 / 骨代謝 / 歯根膜 / 分泌 / エクソソーム … More / エピゲノム / miRNA / メカニカルストレス / 歯根吸収 / HSP72 / HSPA1A / 歯骨細胞 / 破骨細胞 / Heat shock protein … More
Except Principal Investigator
歯根膜 / 歯の移動 / H3k9me3 / H3k9me2 / H3k9me1 / H3K9 metyltransferases / H3K9 / Glp / 歯肉 / G9a / エピジェネティクス / 遺伝子発現 / 免疫関連因子 / コラーゲン線維 / エラスチン / アルカリフォスファターゼ / osterix / MMP12 / 単球、マクロファージ / 免疫系細胞 / 初期変化 / 牽引側歯根膜 / FGF-2 / ICAM-1 / SAPK/JNK / bFGF / VEGF / 血管組織 / 網羅的遺伝子解析 / 免疫組織化学 / 血管関連遺伝子 / 弱い圧迫 / 強い圧迫 / 断続的矯正力 Less
  • Research Projects

    (8 results)
  • Research Products

    (40 results)
  • Co-Researchers

    (12 People)
  •  Exploration for exosome-borne signal transduction during alveolar bone remodeling under orthodontic force applicationPrincipal Investigator

    • Principal Investigator
      新井 千博
    • Project Period (FY)
      2022 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57070:Developmental dentistry-related
    • Research Institution
      Tsurumi University
  •  Study of prevention of orthodontically induced root resorption; focusing on the role of HSP72.Principal Investigator

    • Principal Investigator
      Arai Chihiro
    • Project Period (FY)
      2018 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57070:Developmental dentistry-related
    • Research Institution
      Tsurumi University
  •  Elucidation of the epigenetically regulation of the phenotype of the periodontal ligament fibroblast

    • Principal Investigator
      Yoshiki Nakamura
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthodontics/Pediatric dentistry
    • Research Institution
      Tsurumi University
  •  The effect of HSPA1A on the rate of orthodontic tooth movement.Principal Investigator

    • Principal Investigator
      Arai Chihiro
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthodontics/Pediatric dentistry
    • Research Institution
      Tsurumi University
  •  The effect of HSPA1A on the osteoclastgenesis during pressure zone of orthodontic tooth movementPrincipal Investigator

    • Principal Investigator
      ARAI Chihiro
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Orthodontic/Pediatric dentistry
    • Research Institution
      Tsurumi University
  •  Function of immunocompetent cells in the tension zone of periodontal ligament in tooth movement

    • Principal Investigator
      NAKAMURA Yoshiki
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthodontic/Pediatric dentistry
    • Research Institution
      Tsurumi University
  •  A study evaluating efficient tooth movement from comprehensive gene

    • Principal Investigator
      NODA Koji
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthodontic/Pediatric dentistry
    • Research Institution
      Tsurumi University
  •  The elucidation of the new osteoclast differentiation factor revealed from the pressure zone of periodontal ligament cells during tooth movementPrincipal Investigator

    • Principal Investigator
      ARAI Chihiro
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Orthodontic/Pediatric dentistry
    • Research Institution
      Tsurumi University

All 2024 2015 2013 2012 2011 2010

All Journal Article Presentation

  • [Journal Article] Mandibular Endochondral Growth Is Specifically Augmented by Nutritional Supplementation with Myo-Inositol Even in Rabbits2024

    • Author(s)
      Shimoyama Miho、Kanzaki Hiroyuki、Tohyama Syunnosuke、Ida Tomomi、Ishikawa Misao、Katsumata Yuta、Arai Chihiro、Wada Satoshi、Manase Shugo、Tomonari Hiroshi
    • Journal Title

      Dentistry Journal

      Volume: 12 Issue: 3 Pages: 49-49

    • DOI

      10.3390/dj12030049

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K10197, KAKENHI-PROJECT-22K10256, KAKENHI-PROJECT-22K10257, KAKENHI-PROJECT-22K10281, KAKENHI-PROJECT-23K09427
  • [Journal Article] Periostin of human periodontal ligament fibroblasts promotes migration of human mesenchymal stem cell through the αvβ3 integrin/FAK/PI3K/Akt pathway.2015

    • Author(s)
      Matsuzawa M, Arai C, Nomura Y, Murata T, Yamakoshi Y, Oida S, Hanada N, Nakamura Y.
    • Journal Title

      Journal of periodontal research

      Volume: 印刷中 Issue: 6 Pages: 855-863

    • DOI

      10.1111/jre.12277

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26462983, KAKENHI-PROJECT-15K11356
  • [Journal Article] Human periodontal ligament fibroblasts are the optimal cell source for induced pluripotent stem cells2012

    • Author(s)
      Nomura Y, Ishikawa M, Yashiro Y, Sanggarnjanavanich S, Yamaguchi T, Arai C, Noda K, Takano Y, Nakamura Y, Hanada N
    • Journal Title

      Histochem Cell Biol

      Volume: 137(6) Pages: 719-732

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24792314
  • [Journal Article] Human periodontal ligament fibroblasts are the optimal cell source for induced pluripotent stem cells2012

    • Author(s)
      Nomura Y, Ishikawa M, Arai C, Noda K, Nakamura Y et al
    • Journal Title

      Histochem CellBiol

      Volume: 137 Pages: 719-732

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23593052
  • [Journal Article] Human periodontal ligament fibroblasts are the optimal cell source for induced pluripotent stem cells2012

    • Author(s)
      Nomura Y, Ishikawa M, Yashiro Y, Sanggarnjanavanich S, Yamaguchi T, Arai C, Noda K, Takano Y, Nakamura Y, Hanada N
    • Journal Title

      Histochem Cell Biol.2012

      Volume: (Epub ahead of print) Issue: 6 Pages: 719-732

    • DOI

      10.1007/s00418-012-0923-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390563, KAKENHI-PROJECT-21659490, KAKENHI-PROJECT-23593052, KAKENHI-PROJECT-24593174
  • [Journal Article] Human periodontal ligament fibroblasts are the optimal source for induced pluripotent stem cells2012

    • Author(s)
      Nomura Y, Arai C, et al
    • Journal Title

      Histochem Cell Biol

      Volume: (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22792072
  • [Journal Article] Fiber system degradation, and periostin and connective tissue growth factor level reduction, in the periodontal ligament of teeth in the absence of masticatory load2011

    • Author(s)
      Choi J W, Arai C, Ishikawa M, Shimoda S, Nakamura Y
    • Journal Title

      J PeriodontalRes

      Volume: 46(5) Pages: 513-521

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23593052
  • [Journal Article] Mechanism of active eruption of molars in adolescent rats2011

    • Author(s)
      Oikawa T, Nomura Y, Arai C, Noda K, Hanada N, Nakamura Y
    • Journal Title

      Eur J Orthod

      Volume: 33(3) Issue: 3 Pages: 221-227

    • DOI

      10.1093/ejo/cjq053

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390563, KAKENHI-PROJECT-23593052
  • [Journal Article] Immunocompetent cells and cytokine expression in the rat periodontal ligament at the initial stage of orthodontic tooth movement2011

    • Author(s)
      Baba S, Kuroda N, Arai C, Nakamura Y, Sato T
    • Journal Title

      Arch OralBiol

      Volume: 56(5) Pages: 466-473

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23593052
  • [Journal Article] Fiber system degradation, and periostin and connective tissue growth factor level reduction, in the periodontal ligament of teeth in the absence of masticatory load2011

    • Author(s)
      Choi J W, Arai C, Ishikawa M, Shimoda S, Nakamura Y
    • Journal Title

      J Periodontal Res

      Volume: 46(5) Pages: 513-521

    • Data Source
      KAKENHI-PROJECT-22792072
  • [Journal Article] Immunocompetent cells and cytokine expression in the rat periodontal ligament at the initial stage of orthodontic tooth movement2011

    • Author(s)
      Baba S, Kuroda N, Arai C, Nakamura Y, Sato T
    • Journal Title

      Arch Oral Biol

      Volume: 56(5) Pages: 466-473

    • Data Source
      KAKENHI-PROJECT-22792072
  • [Journal Article] Mechanism of active eruption of molars in adolescent rats2011

    • Author(s)
      Oikawa T, Nomura Y, Arai C, Noda K, Hanada N and Nakamura Y
    • Journal Title

      Eur J Orthod

      Volume: 33(3) Pages: 221-227

    • Data Source
      KAKENHI-PROJECT-22792072
  • [Journal Article] HSPA1A is upregulated in periodontal ligament at early stage of tooth movement in rats.2010

    • Author(s)
      Arai Chihiro, et al
    • Journal Title

      Histochem Cell Biol.

      Volume: 134 Pages: 337-343

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22792072
  • [Journal Article] Immunocompetent cells and cytokine expression in the rat periodontal ligament at the initial stage of orthodontic tooth movement.2010

    • Author(s)
      Baba S, Kuroda N, Arai C, Nakamura Y, Sato T.
    • Journal Title

      Arch Oral Biol.

      Volume: (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22792072
  • [Journal Article] Mechanism of active eruption of molars in adolescent rats.2010

    • Author(s)
      Oikawa T, Nomura Y, Arai C, et al.
    • Journal Title

      Eur J Orthod

      Volume: (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22792072
  • [Journal Article] Root resorption after experimental tooth movement using superelastic forces in the rat.2010

    • Author(s)
      Noda K, Arai C, Nakamura Y
    • Journal Title

      Eur J Orthod.

      Volume: 32 Pages: 681-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22792072
  • [Journal Article] HSPA1A is upregulated in periodontal ligament at early stageof tooth movement in rats2010

    • Author(s)
      Arai C・Nomura Y・Ishikawa M・Noda K Choi J W・Yashiro Y・Hanada N・NakamuraY
    • Journal Title

      Histochem Cell Biol

      Volume: 134(4) Pages: 337-343

    • Data Source
      KAKENHI-PROJECT-22792072
  • [Journal Article] Root resorption after experimental tooth movement using superelastic forces in the rat2010

    • Author(s)
      Noda K, Arai C, Nakamura Y
    • Journal Title

      Eur J Orthod

      Volume: 32(6) Pages: 681-7

    • Data Source
      KAKENHI-PROJECT-22792072
  • [Presentation] 細胞外のHSPA1Aは歯根膜線維芽細胞に作用してIL6およびIL8の発現を誘導する2015

    • Author(s)
      新井千博 松澤匡純 中村芳樹
    • Organizer
      第74回 日本矯正歯科学会大会
    • Place of Presentation
      マリンメッセ福岡 (福岡県 福岡市)
    • Year and Date
      2015-11-18
    • Data Source
      KAKENHI-PROJECT-26463102
  • [Presentation] 歯根膜線維芽細胞に高発現するCXCL12の機能について2013

    • Author(s)
      八城 祐一、野村 義明、石川美佐緒、新井 千博、野田晃司、花田 信弘、中村 芳樹
    • Organizer
      第55回歯科基礎医学会学術大会・総会
    • Place of Presentation
      岡山コンベンションセンター 岡山県
    • Data Source
      KAKENHI-PROJECT-23593052
  • [Presentation] Function of CXCL12 in Periodontal ligament fibroblasts2013

    • Author(s)
      Y. YASHIRO, C. ARAI, S. WADA, Y. MIYAMOTO Y. NAKAMURA
    • Organizer
      国際骨代謝学会(IBMS)・日本骨代謝学会(JSBMR)第2回合同国際会議
    • Place of Presentation
      神戸国際会議場
    • Year and Date
      2013-05-28
    • Data Source
      KAKENHI-PROJECT-23593052
  • [Presentation] Function of CXCL12 in Periodontal Ligament Fibroblasts2013

    • Author(s)
      Yashiro Y, Arai C, Wada S, Miyamoto Y, Nakamura Y
    • Organizer
      2nd Joint Meeting of the International Bone and Mineral Society and The Japanese Society for Bone and Mineral Research
    • Place of Presentation
      Kobe, Japan
    • Data Source
      KAKENHI-PROJECT-24792314
  • [Presentation] HSPA1Aのヒト歯根膜線維芽細胞に対する影響について2013

    • Author(s)
      新井 千博、松澤 匡純、八城 祐一、中村 芳樹
    • Organizer
      日本矯正歯科学会学術大会
    • Place of Presentation
      長野
    • Data Source
      KAKENHI-PROJECT-24792314
  • [Presentation] Function of CXCL12 in Periodontal ligament fibroblasts2013

    • Author(s)
      Y. YASHIRO, C. ARAI, S. WADA, Y. MIYAMOTO Y. NAKAMURA
    • Organizer
      国際骨代謝学会(IBMS)・日本骨代謝学会(JSBMR)第2回合同国際会議
    • Place of Presentation
      神戸国際会議場 兵庫県
    • Data Source
      KAKENHI-PROJECT-23593052
  • [Presentation] 歯根膜線維芽細胞におけるCXCL12産生およびその機能の検討2013

    • Author(s)
      八城 祐一、野村 義明、石川美佐緒、新井 千博、野田晃司、花田 信弘、中村 芳樹
    • Organizer
      第72回日本矯正歯科学会大会
    • Place of Presentation
      キッセイ文化ホール(長野県松本文化会館)長野県
    • Data Source
      KAKENHI-PROJECT-23593052
  • [Presentation] HSPA1A のヒト歯根膜線維芽細胞に対する影響について2013

    • Author(s)
      新井 千博, 松澤 匡純, 八城 祐一, 中村 芳樹
    • Organizer
      第72回日本矯正歯科学会学術大会
    • Place of Presentation
      松本
    • Data Source
      KAKENHI-PROJECT-24792314
  • [Presentation] 歯の移動時に発現するICAM-1の免疫組織化学的研究2012

    • Author(s)
      野田晃司、八城祐一、宮本 豊、馬場俊輔、石川美佐緒、木暮杏太郎、和田悟史、新井千博、中村芳樹
    • Organizer
      第71回日本矯正歯科学会大会
    • Place of Presentation
      盛岡市アイスアリーナ(岩手県)
    • Data Source
      KAKENHI-PROJECT-23593052
  • [Presentation] 歯の移動時に発現するICAM-1の免疫組織化学的研究2012

    • Author(s)
      野田晃司、八城祐一、宮本豊、馬場俊輔、石川美佐緒、木暮杏太郎、和田悟史、新井千博、中村芳樹
    • Organizer
      第71回日本矯正歯科学会大会
    • Place of Presentation
      盛岡市アイスアリーナ
    • Year and Date
      2012-09-26
    • Data Source
      KAKENHI-PROJECT-23593052
  • [Presentation] レトロウイルスペクターによる歯根膜細胞由来のiPS細胞の樹立とその安全性の検討2012

    • Author(s)
      花田信弘、野村義明、石川美佐緒、八城祐一、新井千博、山口貴央、村田貴俊、野田晃司、高野吉郎、中村芳樹
    • Organizer
      第54回歯科基礎医学会
    • Place of Presentation
      奥羽大学、ビッグアイ
    • Year and Date
      2012-09-14
    • Data Source
      KAKENHI-PROJECT-23593052
  • [Presentation] レトロウイルススペクターによる歯根膜細胞由来のiPS細胞の樹立とその安全性の検討2012

    • Author(s)
      花田信弘、野村義明、石川美佐緒、八城祐一、新井千博、山口貴央、村田貴俊、野田晃司、高野芳郎、中村芳樹
    • Organizer
      第54回歯科基礎医学会大会
    • Place of Presentation
      奥羽大学(福島県)
    • Data Source
      KAKENHI-PROJECT-23593052
  • [Presentation] 歯の移動時に発現するbFGFの免疫組織化学的研究2012

    • Author(s)
      石川美佐緒、野田晃司、八城祐一、宮本豊、馬場俊輔、木暮杏太郎、和田悟史、新井千博、中村芳樹
    • Organizer
      第71回日本矯正歯科学会大会
    • Place of Presentation
      盛岡市アイスアリーナ
    • Year and Date
      2012-09-26
    • Data Source
      KAKENHI-PROJECT-23593052
  • [Presentation] 歯の移動時に発現するbFGFの免疫組織化学的研究2012

    • Author(s)
      石川美佐緒、野田晃司、八城祐一、宮本 豊、馬場俊輔、木暮杏太郎、和田悟史、新井千博、中村芳樹
    • Organizer
      第71回日本矯正歯科学会大会
    • Place of Presentation
      盛岡市アイスアリーナ(岩手県)
    • Data Source
      KAKENHI-PROJECT-23593052
  • [Presentation] ヒト歯根膜線維芽細胞からのiPS細胞の樹立2011

    • Author(s)
      石川美佐緒、野村義明、八城祐一、Seetala Sanggarnjanavanjch、山口貴央、新井千博、野田晃司、花田信弘、中村芳樹
    • Organizer
      第53回歯科基礎医学会学術大会
    • Place of Presentation
      岐阜
    • Year and Date
      2011-09-30
    • Data Source
      KAKENHI-PROJECT-23593052
  • [Presentation] ヒト歯根膜線維芽細胞からのiPS細胞の樹立2011

    • Author(s)
      石川美佐緒、新井千博, 他
    • Organizer
      日本矯正科歯科学会大会
    • Place of Presentation
      愛知県名古屋国際会議場
    • Data Source
      KAKENHI-PROJECT-22792072
  • [Presentation] ヒト歯根膜線維芽細胞からのiPS細胞の樹立2011

    • Author(s)
      石川美佐緒、八城祐一、新井千博、野田晃司、中村芳樹
    • Organizer
      第53回歯科基礎医学会学術大会ならびに総会
    • Place of Presentation
      長良川国際会議場
    • Data Source
      KAKENHI-PROJECT-23593052
  • [Presentation] β2アゴニストによるラット咬筋の肥大と速筋化に対する糖質コルチコイドの拮抗作用2011

    • Author(s)
      梅木大輔、新井千博、中村芳樹他
    • Organizer
      第53回歯科基礎医学会学術大会ならびに総会
    • Place of Presentation
      長良川国際会議場
    • Data Source
      KAKENHI-PROJECT-23593052
  • [Presentation] β2アゴニストによるラット咬筋の肥大と速筋化に対する糖質コルチコイドの拮抗作用2011

    • Author(s)
      梅木大輔、大貫芳樹、新井千博、中村芳樹
    • Organizer
      第53回歯科基礎医学会学術大会
    • Place of Presentation
      長良川国際会議場
    • Year and Date
      2011-09-30
    • Data Source
      KAKENHI-PROJECT-23593052
  • [Presentation] HSP70 is Highly Expressed in PDL During the Tooth Movement2010

    • Author(s)
      C. Arai, Y. Nomura, M. Ishikawa, J-W. Choi, K. Noda, S. Imai, N. Hanada, Y. Nakamura
    • Organizer
      88^<th> General Session & Exhibition of the IADR
    • Place of Presentation
      Barcelona
    • Data Source
      KAKENHI-PROJECT-22792072
  • [Presentation] 圧迫側歯根膜に発現する熱ショックタンパク質について2010

    • Author(s)
      新井千博, 他
    • Organizer
      第69回日本矯正歯科学会大会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-22792072
  • [Presentation] 圧迫側歯根膜に発現する熱ショックタンパク質について2010

    • Author(s)
      新井千博、野村義明、野田晃司、石川美佐緒、崔齊原、八城祐一、花田信弘、中村芳樹
    • Organizer
      第69回日本矯正歯科学会学術大会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-22792072
  • 1.  NAKAMURA Yoshiki (10097321)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 20 results
  • 2.  NODA Koji (10148059)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 11 results
  • 3.  HANADA Nobuhiro (70180916)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 7 results
  • 4.  NOMURA Yoshiaki (90350587)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 8 results
  • 5.  WADA Satoshi (20581119)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 7 results
  • 6.  菅崎 弘幸 (30333826)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 7.  石川 美佐緒 (90582445)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 8.  高野 吉郎 (90126425)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  遠山 俊之介 (10908940)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  勝又 裕太 (70886423)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 11.  大井田 新一郎
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 12.  山越 康雄
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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