Naganuma Yasushi 長沼靖

Researcher Number	10463811
Affiliation (Current)	2025: 山形大学, 医学部, 客員研究員
Affiliation (based on the past Project Information) *help	2017 – 2020: 山形大学, 医学部, 客員研究員
Review Section/Research Field	Principal Investigator Basic Section 56020:Orthopedics-related Except Principal Investigator Basic Section 56020:Orthopedics-related / Orthopaedic surgery
Keywords	Principal Investigator 関節炎 / 腸内細菌叢 / 関節リウマチ / 腸管免疫 Except Principal Investigator 自然免疫 / 関節リウマチ / インプラント感染症 / 生体反応 / 感染 / インプラント感染 … More / 選択的オートファジー / 自然免疫受容体 / 人工関節インプラント感染症 / 変形性関節症 / 人工関節 / 炎症性滑膜組織 / オートファジー / 人工関節周囲感染 / 薬剤反応性 / 免疫学 / 薬剤抵抗性 / グレード分類 / 疾患活動性 / 炎症性サイトカイン / 炎症性免疫担当細胞 / 獲得免疫 / 制御性免疫 / Toll様受容体 / 薬剤耐性 Less

Elucidation of intestinal immunoregulatory mechanism in arthritisPrincipal Investigator
- Principal Investigator
  
  Naganuma Yasushi
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Yamagata University
Innate immune receptor and alternative autophagy in pathogenesis of prosthetic joint infection
- Principal Investigator
  
  Takagi Michiaki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Yamagata University
The role of innate immunology in the patients with early rheumatoid arthritis and resistant-anti rheumatic drugs
- Principal Investigator
  
  Takakubo Yuya
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Yamagata University

All 2020 2019 2018

All Journal Article Presentation

[Journal Article] Strategy for the treatment of lateral epicondylitis of the elbow using denervation surgery2020
- Author(s)
  Satake H, Honma R, Naganuma Y**, Shibuya J**, Takagi M
- Journal Title
  
  JSES International
  
  Volume: 22 Pages: 3032-38
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02917
[Journal Article] Rapid disappearing of gouty tophi of foot due to reducing urate pool by resection of huge gouty tophi of opposite foot in the patient with hyperuricemia; a case of report.2019
- Author(s)
  Takakubo Y, Imamura Y, Tezuka H, Okada S, Naganuma Y, Ito J, Sugawara M, Yang S, Oki H, Sasaki A, Sasaki K, Takagi M
- Journal Title
  
  Modern Rheumatology Case Reports
  
  Volume: 4 Issue: 1 Pages: 1-6
- DOI
  10.1080/24725625.2019.1680135
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02917, KAKENHI-PROJECT-17K10995
[Journal Article] 生物学的製剤使用関節リウマチ患者における整形外科手術の検討.2019
- Author(s)
  高窪祐弥, 大木弘治, 長沼靖、梁秀蘭、高木理彰
- Journal Title
  
  関節の外科
  
  Volume: 45 Pages: 101-104
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10995
[Journal Article] intestinal immunity and flora in a collagen-induced mouse parthritis model: differences during arthritis progression.2019
- Author(s)
  Nemoto N, Takeda Y, Nara H, Araki A, Gazi Y, Takakubo Y, Naganuma Y, Takagi M, Asao H
- Journal Title
  
  Int Immunol.
  
  Volume: 32 Issue: 1 Pages: 49-56
- DOI
  10.1093/intimm/dxz058
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02917, KAKENHI-PROJECT-17K10995, KAKENHI-PROJECT-18K16644
[Presentation] Radiographic joint destruction in the patients with rheumatoid arthritis who have withdrawn, spaced or continued biologics after reaching remission from local biologics registry.2019
- Author(s)
  Nagai J, Takakubo Y, Yang S, Suzuki Y, Sasaki A**, Oki H**, Naganuma Y**, Sasaki K**, Takagi M
- Organizer
  The 92nd Annual Meeting of the Japanese Orthopaedic Association
- Data Source
  KAKENHI-PROJECT-17K10995
[Presentation] Utility of alpha-defesin lateral flow device for periprosthetic joint onfection and septic arthritis.2019
- Author(s)
  Narita A, Suzuki A, Nakajima, Takakubo Y, Ito J, Yuki I, Oki H, Naganuma Y, Takagi M
- Organizer
  ORS 2019 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02917
[Presentation] Distrbution of Toll-like receptors expressing immune-cells in rheumatoid synovial tissues of the patients who received CTLA4-Ig agent.2019
- Author(s)
  1.Takakubo Y, Oki H, Yang S, Sasaki A, Sasaki K, Naganuma Y, KatoY, Takagi M
- Organizer
  ORS 2019 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10995
[Presentation] Distrbution of Toll-like receptors expressing immune-cells in rheumatoid synovial tissues of the patients who received CTLA4-Ig agent.2019
- Author(s)
  Takakubo Y, Oki H, Yang S, Sasaki A, Sasaki K, Naganuma Y, KatoY, Takagi M
- Organizer
  ORS 2019 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02917
[Presentation] Radiographic joint destruction in the patients with rheumatoid arthritis who have withdrawn, spaced or continued biologics after reaching remission from local biologics registry.2019
- Author(s)
  Nagai J, Takakubo Y, Yang S, Suzuki Y, Sasaki A, Oki H, Naganuma Y**, Sasaki K**, Takagi M
- Organizer
  The 92nd Annual Meeting of the Japanese Orthopaedic Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02917
[Presentation] Distribution of immune-suppressive cells and Toll-like receptors in synovial tissues in the patients with rheumatoid arthritis which were treated by anti-TNF agents2019
- Author(s)
  Takakubo Y, Yang S, Suzuki Y, Oki H, Naganuma Y**, Sasaki A**, Sasaki K**, Orui H**, Takagi M
- Organizer
  The 63rd Annual General Assembly and Scientific Meeting of the Japan College of Rheumatology
- Data Source
  KAKENHI-PROJECT-18H02917
[Presentation] Utility of alpha-defesin lateral flow device for periprosthetic joint onfection and septic arthritis.2019
- Author(s)
  Narita A, Suzuki A, Nakajima, Takakubo Y, Ito J, Yuki I, Oki H, Naganuma Y, Takagi M
- Organizer
  ORS 2019 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10995
[Presentation] Radiographic joint destruction in the patients with rheumatoid arthritis who have withdrawn, spaced or continued biologics after reaching remission from local biologics registry2019
- Author(s)
  Nagai J, Takakubo Y, Yang S, Suzuki Y, Sasaki A**, Oki H**, Naganuma Y**, Sasaki K**, Takagi M
- Organizer
  The 92nd Annual Meeting of the Japanese Orthopaedic Association
- Data Source
  KAKENHI-PROJECT-18H02917
[Presentation] Toll-like receptors and immune-cells in rheumatoid synovial tissues treated by tocilizumab (TCZ)2018
- Author(s)
  Yuya Takakubo; Tomoto Suzuki; Hiroharu Oki; Nobuhito Nemoto; Yasushi Naganuma; Yuta Suzuki; Kan Sasaki; Michiaki Takagi
- Organizer
  第4回日本骨免疫学会
- Data Source
  KAKENHI-PROJECT-18K16644
[Presentation] Analysis of radiographic joint destruction in rheumatoid patients who have withdrawn, spaced and continued of biologics after achieving sustained remission from local biologics registry.2018
- Author(s)
  Takakubo Y, Nagai J, Naganuma Y, et al.
- Organizer
  European League Against Rheumatism 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10995

1. Takakubo Yuya (80431641)

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
2. Takagi Michiaki (40241707)

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
3. 佐々木幹 (00444034)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
4. 大木弘治 (20463812)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
5. 伊藤重治 (50764122)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results

Naganuma Yasushi 長沼 靖

Research Projects

Research Products

Co-Researchers

Elucidation of intestinal immunoregulatory mechanism in arthritisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Innate immune receptor and alternative autophagy in pathogenesis of prosthetic joint infection

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The role of innate immunology in the patients with early rheumatoid arthritis and resistant-anti rheumatic drugs

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Strategy for the treatment of lateral epicondylitis of the elbow using denervation surgery2020

Author(s)

Journal Title

Data Source

[Journal Article] Rapid disappearing of gouty tophi of foot due to reducing urate pool by resection of huge gouty tophi of opposite foot in the patient with hyperuricemia; a case of report.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 生物学的製剤使用関節リウマチ患者における整形外科手術の検討.2019

Author(s)

Journal Title

Data Source

[Journal Article] intestinal immunity and flora in a collagen-induced mouse parthritis model: differences during arthritis progression.2019

Author(s)

Journal Title

DOI

Data Source

[Presentation] Radiographic joint destruction in the patients with rheumatoid arthritis who have withdrawn, spaced or continued biologics after reaching remission from local biologics registry.2019

Author(s)

Organizer

Data Source

[Presentation] Utility of alpha-defesin lateral flow device for periprosthetic joint onfection and septic arthritis.2019

Author(s)

Organizer

Data Source

[Presentation] Distrbution of Toll-like receptors expressing immune-cells in rheumatoid synovial tissues of the patients who received CTLA4-Ig agent.2019

Author(s)

Organizer

Data Source

[Presentation] Distrbution of Toll-like receptors expressing immune-cells in rheumatoid synovial tissues of the patients who received CTLA4-Ig agent.2019

Author(s)

Organizer

Data Source

[Presentation] Radiographic joint destruction in the patients with rheumatoid arthritis who have withdrawn, spaced or continued biologics after reaching remission from local biologics registry.2019

Author(s)

Organizer

Data Source

[Presentation] Distribution of immune-suppressive cells and Toll-like receptors in synovial tissues in the patients with rheumatoid arthritis which were treated by anti-TNF agents2019

Author(s)

Organizer

Data Source

[Presentation] Utility of alpha-defesin lateral flow device for periprosthetic joint onfection and septic arthritis.2019

Author(s)

Organizer

Data Source

[Presentation] Radiographic joint destruction in the patients with rheumatoid arthritis who have withdrawn, spaced or continued biologics after reaching remission from local biologics registry2019

Author(s)

Organizer

Data Source

[Presentation] Toll-like receptors and immune-cells in rheumatoid synovial tissues treated by tocilizumab (TCZ)2018

Author(s)

Organizer

Data Source

[Presentation] Analysis of radiographic joint destruction in rheumatoid patients who have withdrawn, spaced and continued of biologics after achieving sustained remission from local biologics registry.2018

Author(s)

Organizer

Data Source

Naganuma Yasushi 長沼靖